Phosphodiesterase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30032008 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783]) HSP 1 Score: 509.605 bits (1311), Expect = 9.669e-172 Identity = 262/546 (47.99%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S++I TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 44 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEFISNTFLDKQHEVE-IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 578
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783]) HSP 1 Score: 509.22 bits (1310), Expect = 1.630e-171 Identity = 262/545 (48.07%), Postives = 366/545 (67.16%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S++I TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 53 GLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEFISNTFLDKQHEVE-IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 586
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783]) HSP 1 Score: 509.22 bits (1310), Expect = 1.954e-171 Identity = 262/546 (47.99%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S++I TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 64 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEFISNTFLDKQHEVEIP-SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 598
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783]) HSP 1 Score: 508.064 bits (1307), Expect = 2.771e-171 Identity = 262/546 (47.99%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S++I TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 38 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEFISNTFLDKQHEVE-IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 572
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783]) HSP 1 Score: 508.064 bits (1307), Expect = 3.463e-171 Identity = 262/546 (47.99%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S++I TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 43 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEFISNTFLDKQHEVEIP-SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 577
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 460.685 bits (1184), Expect = 3.257e-154 Identity = 245/551 (44.46%), Postives = 355/551 (64.43%), Query Frame = 3
Query: 411 RRESFLYKYEED----SSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSD--IFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRF-GISFTEA-SYINEVFESSLNT-------------WSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
RRESFLY+ +D SS+ P SR +S+ S E + D+IVTPFAQ+LA L +R+N+ + ++ D+ H N + E D + A +++ LDWCL LE IQT RSVS +A+ KF+KMLN EL + E+ SK+ Q+S ++ TT+++ D + + + S + K ++ G+ A S+ V E +N W D+F+I E+S N LT+VT+++ + R + +TF I L+ +LL +E +Y++ YHN IHAADV Q+ +V+L S L +FTDLE+ + +FA +HDV HPG TNQ+LIN+N+ LA +YND+SVLE HHLA +F +++D N D L NL++++R FRK VIDMVLATDMS+HM+LLADLKTMVE KKV+G+ ++ +DKYND++ +LQ+++H ADLSNPTKP +Y++W RIMEE++ QGDKEKELGL++S MCDR N ++K+QVGFIDYIVHPL+E W +LV+PDA ++L+ L ENR +Y ++
Sbjct: 42 RRESFLYRASDDLREASSLRP--VSRASSIASNEHGHGD---DLIVTPFAQLLASLRNVRSNLISITNIQNSDDSR---HANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAES---SKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVRKLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSR 581
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 460.299 bits (1183), Expect = 5.297e-154 Identity = 245/551 (44.46%), Postives = 355/551 (64.43%), Query Frame = 3
Query: 411 RRESFLYKYEED----SSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSD--IFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRF-GISFTEA-SYINEVFESSLNT-------------WSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
RRESFLY+ +D SS+ P SR +S+ S E + D+IVTPFAQ+LA L +R+N+ + ++ D+ H N + E D + A +++ LDWCL LE IQT RSVS +A+ KF+KMLN EL + E+ SK+ Q+S ++ TT+++ D + + + S + K ++ G+ A S+ V E +N W D+F+I E+S N LT+VT+++ + R + +TF I L+ +LL +E +Y++ YHN IHAADV Q+ +V+L S L +FTDLE+ + +FA +HDV HPG TNQ+LIN+N+ LA +YND+SVLE HHLA +F +++D N D L NL++++R FRK VIDMVLATDMS+HM+LLADLKTMVE KKV+G+ ++ +DKYND++ +LQ+++H ADLSNPTKP +Y++W RIMEE++ QGDKEKELGL++S MCDR N ++K+QVGFIDYIVHPL+E W +LV+PDA ++L+ L ENR +Y ++
Sbjct: 55 RRESFLYRASDDLREASSLRP--VSRASSIASNEHGHGD---DLIVTPFAQLLASLRNVRSNLISITNIQNSDDSR---HANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAES---SKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVRKLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSR 594
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 462.225 bits (1188), Expect = 6.733e-154 Identity = 249/578 (43.08%), Postives = 362/578 (62.63%), Query Frame = 3
Query: 345 FSNKKIRESKSFGGLQIQNN-----SQRRESFLYKYEED----SSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSD--IFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRF-GISFTEA-SYINEVFESSLNT-------------WSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
FS + GG + + RRESFLY+ +D SS+ P SR +S+ S E + D+IVTPFAQ+LA L +R+N+ + ++ D+ H N + E D + A +++ LDWCL LE IQT RSVS +A+ KF+KMLN EL + E+ SK+ Q+S ++ TT+++ D + + + S + K ++ G+ A S+ V E +N W D+F+I E+S N LT+VT+++ + R + +TF I L+ +LL +E +Y++ YHN IHAADV Q+ +V+L S L +FTDLE+ + +FA +HDV HPG TNQ+LIN+N+ LA +YND+SVLE HHLA +F +++D N D L NL++++R FRK VIDMVLATDMS+HM+LLADLKTMVE KKV+G+ ++ +DKYND++ +LQ+++H ADLSNPTKP +Y++W RIMEE++ QGDKEKELGL++S MCDR N ++K+QVGFIDYIVHPL+E W +LV+PDA ++L+ L ENR +Y ++
Sbjct: 90 FSAGSATAADGLGGAHLTPSLSSSVHARRESFLYRASDDLREASSLRP--VSRASSIASNEHGHGD---DLIVTPFAQLLASLRNVRSNLISITNIQNSDDSR---HANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAES---SKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVRKLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSR 656
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 460.299 bits (1183), Expect = 1.042e-153 Identity = 245/551 (44.46%), Postives = 355/551 (64.43%), Query Frame = 3
Query: 411 RRESFLYKYEED----SSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSD--IFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRF-GISFTEA-SYINEVFESSLNT-------------WSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
RRESFLY+ +D SS+ P SR +S+ S E + D+IVTPFAQ+LA L +R+N+ + ++ D+ H N + E D + A +++ LDWCL LE IQT RSVS +A+ KF+KMLN EL + E+ SK+ Q+S ++ TT+++ D + + + S + K ++ G+ A S+ V E +N W D+F+I E+S N LT+VT+++ + R + +TF I L+ +LL +E +Y++ YHN IHAADV Q+ +V+L S L +FTDLE+ + +FA +HDV HPG TNQ+LIN+N+ LA +YND+SVLE HHLA +F +++D N D L NL++++R FRK VIDMVLATDMS+HM+LLADLKTMVE KKV+G+ ++ +DKYND++ +LQ+++H ADLSNPTKP +Y++W RIMEE++ QGDKEKELGL++S MCDR N ++K+QVGFIDYIVHPL+E W +LV+PDA ++L+ L ENR +Y ++
Sbjct: 69 RRESFLYRASDDLREASSLRP--VSRASSIASNEHGHGD---DLIVTPFAQLLASLRNVRSNLISITNIQNSDDSR---HANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAES---SKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVRKLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSR 608
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 459.914 bits (1182), Expect = 1.295e-153 Identity = 245/551 (44.46%), Postives = 355/551 (64.43%), Query Frame = 3
Query: 411 RRESFLYKYEED----SSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSD--IFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRF-GISFTEA-SYINEVFESSLNT-------------WSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
RRESFLY+ +D SS+ P SR +S+ S E + D+IVTPFAQ+LA L +R+N+ + ++ D+ H N + E D + A +++ LDWCL LE IQT RSVS +A+ KF+KMLN EL + E+ SK+ Q+S ++ TT+++ D + + + S + K ++ G+ A S+ V E +N W D+F+I E+S N LT+VT+++ + R + +TF I L+ +LL +E +Y++ YHN IHAADV Q+ +V+L S L +FTDLE+ + +FA +HDV HPG TNQ+LIN+N+ LA +YND+SVLE HHLA +F +++D N D L NL++++R FRK VIDMVLATDMS+HM+LLADLKTMVE KKV+G+ ++ +DKYND++ +LQ+++H ADLSNPTKP +Y++W RIMEE++ QGDKEKELGL++S MCDR N ++K+QVGFIDYIVHPL+E W +LV+PDA ++L+ L ENR +Y ++
Sbjct: 67 RRESFLYRASDDLREASSLRP--VSRASSIASNEHGHGD---DLIVTPFAQLLASLRNVRSNLISITNIQNSDDSR---HANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAES---SKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVRKLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSR 606
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333314) HSP 1 Score: 504.982 bits (1299), Expect = 4.542e-170 Identity = 266/584 (45.55%), Postives = 374/584 (64.04%), Query Frame = 3
Query: 381 GGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLS---KESNSAECV-----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDE-----KENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIAD---GKEKNLDKKIFSR------------------------------FGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +QN QRRESFLY+ + D +SP+ SR +S+ S KE ++ V ED+IVTPFAQILA L +R N+ + + ++ + + + N E + A +++ LDWCL LE IQT RSVS +A++KFK+MLN EL + E+ S++ +QIS+YIC+TFL+ + D L S+ + NPE +A +++ + SR FG+ + + + L+TW I +F I E S N LT V Y IF++R+++ + IP +NF+ +E +Y K P+HNS+HAADV Q+ NV+L + AL+ +FT LE+ LFA IHDV HPG+TNQFL+N++ LA +YND+SVLENHHLA +F +++++ DI N+ K++R T RK VID+VL+TDMS+HM+LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WV+ +MEEFFLQGDKE+E G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL ENR +Y
Sbjct: 38 AGLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSES---SRSGNQISEYICSTFLDKQQEFD------LPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 611
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333313) HSP 1 Score: 504.982 bits (1299), Expect = 4.542e-170 Identity = 266/584 (45.55%), Postives = 374/584 (64.04%), Query Frame = 3
Query: 381 GGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLS---KESNSAECV-----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDE-----KENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIAD---GKEKNLDKKIFSR------------------------------FGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +QN QRRESFLY+ + D +SP+ SR +S+ S KE ++ V ED+IVTPFAQILA L +R N+ + + ++ + + + N E + A +++ LDWCL LE IQT RSVS +A++KFK+MLN EL + E+ S++ +QIS+YIC+TFL+ + D L S+ + NPE +A +++ + SR FG+ + + + L+TW I +F I E S N LT V Y IF++R+++ + IP +NF+ +E +Y K P+HNS+HAADV Q+ NV+L + AL+ +FT LE+ LFA IHDV HPG+TNQFL+N++ LA +YND+SVLENHHLA +F +++++ DI N+ K++R T RK VID+VL+TDMS+HM+LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WV+ +MEEFFLQGDKE+E G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL ENR +Y
Sbjct: 38 AGLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSES---SRSGNQISEYICSTFLDKQQEFD------LPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 611
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333317) HSP 1 Score: 505.368 bits (1300), Expect = 6.447e-170 Identity = 266/584 (45.55%), Postives = 374/584 (64.04%), Query Frame = 3
Query: 381 GGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLS---KESNSAECV-----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDE-----KENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIAD---GKEKNLDKKIFSR------------------------------FGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +QN QRRESFLY+ + D +SP+ SR +S+ S KE ++ V ED+IVTPFAQILA L +R N+ + + ++ + + + N E + A +++ LDWCL LE IQT RSVS +A++KFK+MLN EL + E+ S++ +QIS+YIC+TFL+ + D L S+ + NPE +A +++ + SR FG+ + + + L+TW I +F I E S N LT V Y IF++R+++ + IP +NF+ +E +Y K P+HNS+HAADV Q+ NV+L + AL+ +FT LE+ LFA IHDV HPG+TNQFL+N++ LA +YND+SVLENHHLA +F +++++ DI N+ K++R T RK VID+VL+TDMS+HM+LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WV+ +MEEFFLQGDKE+E G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL ENR +Y
Sbjct: 50 AGLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSES---SRSGNQISEYICSTFLDKQQEFD------LPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 623
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333316) HSP 1 Score: 505.368 bits (1300), Expect = 6.447e-170 Identity = 266/584 (45.55%), Postives = 374/584 (64.04%), Query Frame = 3
Query: 381 GGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLS---KESNSAECV-----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDE-----KENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIAD---GKEKNLDKKIFSR------------------------------FGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +QN QRRESFLY+ + D +SP+ SR +S+ S KE ++ V ED+IVTPFAQILA L +R N+ + + ++ + + + N E + A +++ LDWCL LE IQT RSVS +A++KFK+MLN EL + E+ S++ +QIS+YIC+TFL+ + D L S+ + NPE +A +++ + SR FG+ + + + L+TW I +F I E S N LT V Y IF++R+++ + IP +NF+ +E +Y K P+HNS+HAADV Q+ NV+L + AL+ +FT LE+ LFA IHDV HPG+TNQFL+N++ LA +YND+SVLENHHLA +F +++++ DI N+ K++R T RK VID+VL+TDMS+HM+LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WV+ +MEEFFLQGDKE+E G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL ENR +Y
Sbjct: 50 AGLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSES---SRSGNQISEYICSTFLDKQQEFD------LPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 623
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070517) HSP 1 Score: 504.597 bits (1298), Expect = 7.562e-170 Identity = 266/584 (45.55%), Postives = 374/584 (64.04%), Query Frame = 3
Query: 381 GGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLS---KESNSAECV-----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDE-----KENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIAD---GKEKNLDKKIFSR------------------------------FGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +QN QRRESFLY+ + D +SP+ SR +S+ S KE ++ V ED+IVTPFAQILA L +R N+ + + ++ + + + N E + A +++ LDWCL LE IQT RSVS +A++KFK+MLN EL + E+ S++ +QIS+YIC+TFL+ + D L S+ + NPE +A +++ + SR FG+ + + + L+TW I +F I E S N LT V Y IF++R+++ + IP +NF+ +E +Y K P+HNS+HAADV Q+ NV+L + AL+ +FT LE+ LFA IHDV HPG+TNQFL+N++ LA +YND+SVLENHHLA +F +++++ DI N+ K++R T RK VID+VL+TDMS+HM+LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WV+ +MEEFFLQGDKE+E G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL ENR +Y
Sbjct: 36 AGLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSES---SRSGNQISEYICSTFLDKQQEFD------LPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 609
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373]) HSP 1 Score: 521.546 bits (1342), Expect = 3.966e-176 Identity = 282/625 (45.12%), Postives = 396/625 (63.36%), Query Frame = 3
Query: 174 GSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIP-IPKKDHINNLKDNFSNKKIRESKSFGGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFS---DIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISK----KSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
G+ P S K+ ++ + + + M S+ R+F + P D N L S + S GL +Q N SQRRESFLY+ + D +SP+ SR +S S+ ED+IVTPFAQ+LA L +R+N + + +++ + ++ C+ S + F+ A E++ LDWCL LE ++T SVS +A+ KFK+MLN EL Q ET SK+ +Q+S+YI +TFLE D D +S+ SK K P G +K N+ RFG+S + + E + W +D+F+I E S N LT+ Y F+ R ++++F IP D IN++ +E NY+S + YHNSIHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIM EFF QGD+E++ G+++S MCD+ N++++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 1 GNSPTGSPKMSPRSSPRNSPLLFRRLMMN---RSIALQRRFTLAHTPSFDVENGLSVGRSPLDSQASPG-SGLVLQANFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELHG-----EDMIVTPFAQVLASLRTVRSNFA------VLTHQQDRVPSKKSTGNNPPSMCKTSLPEEPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSET---SKSGNQVSEYISSTFLEKQHDMD-----IMSTPSKEKEKKKRPMSQISGVKKPTHSSNIAPSSIPRFGVSTNREDLLAKELED-FDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWY 601
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4cb (phosphodiesterase 4C, cAMP-specific b [Source:ZFIN;Acc:ZDB-GENE-030131-4075]) HSP 1 Score: 519.62 bits (1337), Expect = 8.811e-176 Identity = 265/542 (48.89%), Postives = 364/542 (67.16%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q NSQRRESFLY+ + D +SP+ SR +S S+ ED+IVTPFAQ+LA L +R NV+ + ++ K N + NL+ E E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +T L+ +D + + C KK P G K +L RFG++ S + + E L+ W ID+F+I E S N LT++ Y IF+ R +++TF IP+D + FL+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+++FTDLEI + LFA IHDV HPGVTNQFLINTN LA +YND SVLENHHLA F +++++N DI NL+K++R + R+ IDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+DVS MCD+ ++++ TQVGFIDYI+HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 62 GLVLQANSQRRESFLYRSDSDFDLSPKTMSRNSSTASELHG-----EDMIVTPFAQVLASLRTVRGNVAALTHMQDRSNKRPS-GTNPQSACKTNLSDEAYQKLTV-ETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTILQKQYDVELLSAACKEE--KKRRPMSQISGVRKLSPSPSLPPTCIPRFGVNTQHESLLAKELED-LDRWGIDIFKIAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRERDKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHPDAQDILDTLEDNREWY 590
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4cb (phosphodiesterase 4C, cAMP-specific b [Source:ZFIN;Acc:ZDB-GENE-030131-4075]) HSP 1 Score: 518.85 bits (1335), Expect = 1.342e-175 Identity = 265/542 (48.89%), Postives = 364/542 (67.16%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q NSQRRESFLY+ + D +SP+ SR +S S+ ED+IVTPFAQ+LA L +R NV+ + ++ K N + NL+ E E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +T L+ +D + + C KK P G K +L RFG++ S + + E L+ W ID+F+I E S N LT++ Y IF+ R +++TF IP+D + FL+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+++FTDLEI + LFA IHDV HPGVTNQFLINTN LA +YND SVLENHHLA F +++++N DI NL+K++R + R+ IDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+DVS MCD+ ++++ TQVGFIDYI+HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 49 GLVLQANSQRRESFLYRSDSDFDLSPKTMSRNSSTASELHG-----EDMIVTPFAQVLASLRTVRGNVAALTHMQDRSNKRPS-GTNPQSACKTNLSDEAYQKLTV-ETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTILQKQYDVELLSAACKEE--KKRRPMSQISGVRKLSPSPSLPPTCIPRFGVNTQHESLLAKELED-LDRWGIDIFKIAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRERDKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHPDAQDILDTLEDNREWY 577
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4cb (phosphodiesterase 4C, cAMP-specific b [Source:ZFIN;Acc:ZDB-GENE-030131-4075]) HSP 1 Score: 518.079 bits (1333), Expect = 2.711e-175 Identity = 265/542 (48.89%), Postives = 364/542 (67.16%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q NSQRRESFLY+ + D +SP+ SR +S S+ ED+IVTPFAQ+LA L +R NV+ + ++ K N + NL+ E E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +T L+ +D + + C KK P G K +L RFG++ S + + E L+ W ID+F+I E S N LT++ Y IF+ R +++TF IP+D + FL+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+++FTDLEI + LFA IHDV HPGVTNQFLINTN LA +YND SVLENHHLA F +++++N DI NL+K++R + R+ IDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+DVS MCD+ ++++ TQVGFIDYI+HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 62 GLVLQANSQRRESFLYRSDSDFDLSPKTMSRNSSTASELHG-----EDMIVTPFAQVLASLRTVRGNVAALTHMQDRSNKRPS-GTNPQSACKTNLSDEAYQKLTV-ETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTILQKQYDVELLSAACKEE--KKRRPMSQISGVRKLSPSPSLPPTCIPRFGVNTQHESLLAKELED-LDRWGIDIFKIAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRERDKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHPDAQDILDTLEDNREWY 590
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4cb (phosphodiesterase 4C, cAMP-specific b [Source:ZFIN;Acc:ZDB-GENE-030131-4075]) HSP 1 Score: 519.235 bits (1336), Expect = 3.162e-175 Identity = 265/542 (48.89%), Postives = 364/542 (67.16%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q NSQRRESFLY+ + D +SP+ SR +S S+ ED+IVTPFAQ+LA L +R NV+ + ++ K N + NL+ E E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +T L+ +D + + C KK P G K +L RFG++ S + + E L+ W ID+F+I E S N LT++ Y IF+ R +++TF IP+D + FL+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+++FTDLEI + LFA IHDV HPGVTNQFLINTN LA +YND SVLENHHLA F +++++N DI NL+K++R + R+ IDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+DVS MCD+ ++++ TQVGFIDYI+HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 90 GLVLQANSQRRESFLYRSDSDFDLSPKTMSRNSSTASELHG-----EDMIVTPFAQVLASLRTVRGNVAALTHMQDRSNKRPS-GTNPQSACKTNLSDEAYQKLTV-ETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTILQKQYDVELLSAACKEE--KKRRPMSQISGVRKLSPSPSLPPTCIPRFGVNTQHESLLAKELED-LDRWGIDIFKIAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRERDKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHPDAQDILDTLEDNREWY 618
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: cab39l (calcium binding protein 39 like [Source:Xenbase;Acc:XB-GENE-953216]) HSP 1 Score: 514.227 bits (1323), Expect = 2.955e-172 Identity = 272/586 (46.42%), Postives = 385/586 (65.70%), Query Frame = 3
Query: 261 LTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFS-----RFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
++RNS R+F + P + N + + ++ GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S ED+IVTPFAQ+LA L +R+N + + L+ + N+ + NL+ + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL ET S++ +Q+S+YI +TFL+ + + + KK P G +K FS RFG+ + + + E+ +N W +D+F++ E S N LT++ Y+IF+ R +++TF+IP D I +++ +E +Y S + YHN+IHAADV Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R T RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RI+ EFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 48 MSRNSRMQ-RRFTVAHPPCFDVENGLSSGRSPLESQASPGSGLVLQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHG-----EDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVSNKRSSGSNQPSACKPNLSEDAVQKL-AIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSET---SRSGNQVSEYISSTFLDKQHEVEIP-TPVSKEKDKKKRPMSQISGVKKLTHSSSFSNCSIPRFGVKTEQEVPLAKEVEN-INKWGLDIFKVAEYSGNRPLTVIMYSIFQERDLLKTFHIPVDTFITYMMTLEDHYHSDVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIIVEFFHQGDREREKGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWY 621
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: cab39l (calcium binding protein 39 like [Source:Xenbase;Acc:XB-GENE-953216]) HSP 1 Score: 510.375 bits (1313), Expect = 1.947e-171 Identity = 265/545 (48.62%), Postives = 369/545 (67.71%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFS-----RFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S ED+IVTPFAQ+LA L +R+N + + L+ + N+ + NL+ + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL ET S++ +Q+S+YI +TFL+ + + + KK P G +K FS RFG+ + + + E+ +N W +D+F++ E S N LT++ Y+IF+ R +++TF+IP D I +++ +E +Y S + YHN+IHAADV Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R T RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RI+ EFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 39 GLVLQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHG-----EDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVSNKRSSGSNQPSACKPNLSEDAVQKL-AIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSET---SRSGNQVSEYISSTFLDKQHEVEIP-TPVSKEKDKKKRPMSQISGVKKLTHSSSFSNCSIPRFGVKTEQEVPLAKEVEN-INKWGLDIFKVAEYSGNRPLTVIMYSIFQERDLLKTFHIPVDTFITYMMTLEDHYHSDVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIIVEFFHQGDREREKGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWY 572
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479]) HSP 1 Score: 507.679 bits (1306), Expect = 3.909e-171 Identity = 263/545 (48.26%), Postives = 363/545 (66.61%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + + E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + E +N W +++F++ E S N LT+V + IF+ R++++TF IP D LI +L+ +E +Y + + YHN+IHAADV Q+ +V+L S AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 45 GLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKL-AGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVE-MPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSENEECLAKELED-VNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 578
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479]) HSP 1 Score: 507.679 bits (1306), Expect = 4.419e-171 Identity = 263/545 (48.26%), Postives = 363/545 (66.61%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + + E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + E +N W +++F++ E S N LT+V + IF+ R++++TF IP D LI +L+ +E +Y + + YHN+IHAADV Q+ +V+L S AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 53 GLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKL-AGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVE-MPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSENEECLAKELED-VNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 586
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: cab39l (calcium binding protein 39 like [Source:Xenbase;Acc:XB-GENE-953216]) HSP 1 Score: 509.99 bits (1312), Expect = 7.763e-171 Identity = 265/545 (48.62%), Postives = 369/545 (67.71%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFS-----RFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S ED+IVTPFAQ+LA L +R+N + + L+ + N+ + NL+ + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL ET S++ +Q+S+YI +TFL+ + + + KK P G +K FS RFG+ + + + E+ +N W +D+F++ E S N LT++ Y+IF+ R +++TF+IP D I +++ +E +Y S + YHN+IHAADV Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R T RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RI+ EFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 67 GLVLQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHG-----EDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVSNKRSSGSNQPSACKPNLSEDAVQKL-AIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSET---SRSGNQVSEYISSTFLDKQHEVEIP-TPVSKEKDKKKRPMSQISGVKKLTHSSSFSNCSIPRFGVKTEQEVPLAKEVEN-INKWGLDIFKVAEYSGNRPLTVIMYSIFQERDLLKTFHIPVDTFITYMMTLEDHYHSDVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIIVEFFHQGDREREKGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWY 600
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555]) HSP 1 Score: 511.531 bits (1316), Expect = 9.298e-173 Identity = 263/546 (48.17%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 44 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVE-IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 578
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555]) HSP 1 Score: 510.375 bits (1313), Expect = 5.126e-172 Identity = 263/546 (48.17%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 66 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVEIP-SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 600
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555]) HSP 1 Score: 510.375 bits (1313), Expect = 5.194e-172 Identity = 263/546 (48.17%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 64 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVEIP-SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 598
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555]) HSP 1 Score: 511.531 bits (1316), Expect = 1.004e-171 Identity = 263/546 (48.17%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 120 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVE-IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 654
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555]) HSP 1 Score: 511.146 bits (1315), Expect = 1.333e-171 Identity = 263/546 (48.17%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 113 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVE-IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q01063|PDE4D_MOUSE (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Mus musculus OX=10090 GN=Pde4d PE=1 SV=2) HSP 1 Score: 511.146 bits (1315), Expect = 9.322e-171 Identity = 263/546 (48.17%), Postives = 366/546 (67.03%), Query Frame = 3
Query: 381 GGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 113 SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVE-IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P14270|PDE4D_RAT (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Rattus norvegicus OX=10116 GN=Pde4d PE=1 SV=4) HSP 1 Score: 510.375 bits (1313), Expect = 1.055e-169 Identity = 262/545 (48.07%), Postives = 365/545 (66.97%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S+YI TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK ID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 170 GLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEYISNTFLDKQHEVEIP-SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 703
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q08499|PDE4D_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens OX=9606 GN=PDE4D PE=1 SV=2) HSP 1 Score: 510.375 bits (1313), Expect = 1.181e-169 Identity = 262/545 (48.07%), Postives = 366/545 (67.16%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ SR +S+ S +D+IVTPFAQ+LA L +R N + + L+ + N+ + +T E A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL E +S++ +Q+S++I TFL+ + + S KK P G +K +L RFG+ + + + E +N W + +F I E+S N LT++ + IF+ R +++TF IP D LI +L+ +E +Y + + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VID+VLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ N++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 175 GLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHG-----DDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKL-ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE---MSRSGNQVSEFISNTFLDKQHEVEIP-SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 708
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q08493|PDE4C_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS=Homo sapiens OX=9606 GN=PDE4C PE=1 SV=2) HSP 1 Score: 505.368 bits (1300), Expect = 4.307e-169 Identity = 257/541 (47.50%), Postives = 361/541 (66.73%), Query Frame = 3
Query: 402 NSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIA--DG-----KEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
+SQRRESFLY+ + D +SP+ SR +SV S ED+IVTPFAQ+LA L +R+NV+ + + + + N + QL E + A E++ LDWCL LE +QT SV +A+ KFK++LN EL ET S++ +Q+S+YI TFL+ + + L ++ + P+ ++ G +L RFG+ + + + E + N W +D+F++ E+S N LT + ++IF+ R +++TF IP D L +LL +E +Y + + YHNS+HAADV Q+ +V+L + AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++ +N DI +NL+ ++R + R+ VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQNLVHCADLSNPTKP +Y +W RIM EFF QGD+E+E GLD+S MCD+ ++V+K+QVGFIDYI HPLWE W +LVHPDA +L+TL +NR +Y +K
Sbjct: 113 HSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHG-----EDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLP-PAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSET---SRSGNQVSEYISRTFLDQQTEVE------LPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDT-NKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSK 637
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q3UEI1|PDE4C_MOUSE (cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS=Mus musculus OX=10090 GN=Pde4c PE=1 SV=1) HSP 1 Score: 503.827 bits (1296), Expect = 8.321e-169 Identity = 253/538 (47.03%), Postives = 357/538 (66.36%), Query Frame = 3
Query: 408 QRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKE------KNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
QRRESFLY+ + D SP+ SR +S S ED+IVTPFAQ+LA L +R NV+ + ++ + + Q T E S + +E++ LDWCL LE +QT RSV +A+ KFK+MLN EL ET S++ +Q+S+YI TFL+ + + L + +P +A E +L RFG+ + + + E + N W +D+F++ E+S N LT V +++F+ R +++TF IP D L+ +LL +E +Y S + YHNS+HAADV+Q+A+V+L + AL+ +FTDLE+ + +FAC IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++ +N DI RNL+ ++R + R+ VIDMVLATDMS+HM+LLADLKTMVETKKV+ G+L +D Y+DR+ +LQ+LVHCADLSNP KP +Y +W RIM EFF QGD+E+E GLD+S MCD+ ++++K+QVGFIDYI PLWE W +LVHPDA +L+TL +NR +Y ++
Sbjct: 117 QRRESFLYRSDSDHEPSPKAVSRTSSAASDLHG-----EDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQVLLGTPPHSSQQAAPT-EDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSET---SRSGNQVSEYISQTFLDQQAEVE------LPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDT-NKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSR 638
BLAST of Phosphodiesterase vs. TrEMBL
Match: U5ER03 (Phosphodiesterase (Fragment) OS=Corethrella appendiculata OX=1370023 PE=2 SV=1) HSP 1 Score: 531.561 bits (1368), Expect = 1.542e-176 Identity = 280/577 (48.53%), Postives = 384/577 (66.55%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAEC----------VEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIH-------LNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRD-----DNYSDCLSSISKKSN------PEDIADGKEKNLDKK---IFSRFGISFTEASYINE--VFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPS 2009
GL +QN QRRESFLY+ + D +SP+ SR +S+ S+ AE VED+IVTPFAQILA L +R N+ + + K N+++ LN DT + L A +++ LDWCL LE +QT RSVS +A++KFK+MLN EL E+ SK+ +QIS+YIC+TFL+ + D + S+ S+ + +S P G ++ L R I E + ++ + S++TW ID+F+I +S+N LT V +AIF+ R+I+ T IP+ I + F+ +E +Y K P+HNS+HAADV Q+ NV+L + AL+N+FT LEI + LFA IHDV HPG+TNQFLIN++ LA +YND+SVLENHHLA +F ++ +++ DILRN+ K++R TFRK VIDMVL+TDMS+HM LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WVS +MEEFFLQGDKE+ G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+ L ENR +Y + PS
Sbjct: 133 GLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERIKEAEVPVVSTTERAHVEDLIVTPFAQILASLRSVRNNLYNLTNVPSQKSKRNNVNQVAQRPPLNPGDDTYVKL---------ALDTIDELDWCLDQLETVQTHRSVSDMASLKFKRMLNKELSHLSES---SKSGNQISEYICSTFLDKQQEVDIPCLREELSESHSAHTTRSRSPRMGPPMSQISGFKRPLTHTNSFTSDRLPIYGVETPHEHQLGIILGSIHTWGIDIFKIESLSNNRPLTCVAFAIFQEREILNTLMIPSKIFLAFMTTLEDHYVKDNPFHNSLHAADVAQSTNVLLNTPALENVFTSLEICAALFAACIHDVDHPGLTNQFLINSSSELAIMYNDESVLENHHLAVAFKLMSNEDCDILRNVQKKQRQTFRKMVIDMVLSTDMSKHMTLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVSLLMEEFFLQGDKERAAGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDMLEENRDYYQSLIPPS 697
BLAST of Phosphodiesterase vs. TrEMBL
Match: Q17KM9 (Phosphodiesterase OS=Aedes aegypti OX=7159 GN=AAEL001629 PE=3 SV=1) HSP 1 Score: 525.013 bits (1351), Expect = 7.217e-174 Identity = 272/565 (48.14%), Postives = 377/565 (66.73%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDN------FDRDDNYS---------------DCLSSISKKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPS 2009
GL +QN QRRESFLY+ + D +SP+ SR +S+ S+ VED+IVTPFAQILA L +R+N + + K N++ + + L E S + A +++ LDWCL LE +QT RSVS +A++KFK+MLN EL E+ SK+ +QIS+YIC+TFL+ + RDD+ S + +S IS P + ++G+ + V + ++TW ID+F I +S+N LT V +AIF+ R I+ T IP+ + + F+ +E +Y K P+HNS+HAADV Q+ +V+L + AL+N+FT LE + LFA IHDV HPG+TNQFLIN++ LA +YND+SVLENHHLA +F ++++++ DILRN+ K++R TFRK VIDMVL+TDMS+HM LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WV+R+MEEFFLQGDKE+ G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+ L ENR +Y + PS
Sbjct: 164 GLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERH-----VEDLIVTPFAQILASLRSVRSNFFNLTNVSPPKSKRNNVQVTP-VAKALTPGDE-SYVKLALDTIDELDWCLDQLETVQTHRSVSDMASLKFKRMLNKELSHLSES---SKSGNQISEYICSTFLDKQQELDIPYSRDDSDSHNPSSFSRSRSPRMGERMSQISGFKRPLQ----HTNSFTSDRLPQYGVDTPHEHQLGPVL-NQIDTWGIDIFRIETLSNNRPLTCVAFAIFQERDILNTLMIPSKVFLAFMTTLEDHYVKDNPFHNSLHAADVAQSTHVLLNTPALENVFTPLETCAALFAACIHDVDHPGLTNQFLINSSSELAIMYNDESVLENHHLAVAFKLLQNEDCDILRNIQKKQRQTFRKMVIDMVLSTDMSKHMTLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPMYKRWVARLMEEFFLQGDKERAAGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDMLEENRDYYQSLIPPS 713
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A0P6J1G4 (Phosphodiesterase OS=Aedes aegypti OX=7159 PE=2 SV=1) HSP 1 Score: 524.628 bits (1350), Expect = 1.429e-173 Identity = 272/565 (48.14%), Postives = 377/565 (66.73%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDN------FDRDDNYS---------------DCLSSISKKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPS 2009
GL +QN QRRESFLY+ + D +SP+ SR +S+ S+ VED+IVTPFAQILA L +R+N + + K N++ + + L E S + A +++ LDWCL LE +QT RSVS +A++KFK+MLN EL E+ SK+ +QIS+YIC+TFL+ + RDD+ S + +S IS P + ++G+ + V + ++TW ID+F I +S+N LT V +AIF+ R I+ T IP+ + + F+ +E +Y K P+HNS+HAADV Q+ +V+L + AL+N+FT LE + LFA IHDV HPG+TNQFLIN++ LA +YND+SVLENHHLA +F ++++++ DILRN+ K++R TFRK VIDMVL+TDMS+HM LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WV+R+MEEFFLQGDKE+ G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+ L ENR +Y + PS
Sbjct: 164 GLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERH-----VEDLIVTPFAQILASLRSVRSNFFNLTNVSPPKSKRNNVQVTP-VAKALTPGDE-SYVKLALDTIDELDWCLDQLETVQTHRSVSDMASLKFKRMLNKELSHLSES---SKSGNQISEYICSTFLDKQQELDIPYSRDDSDSHNPSSFSRSRSPRMGERMSQISGFKRPLQ----HTNSFTSDRLPQYGVDTPHEHQLGPVL-NQIDTWGIDIFRIETLSNNRPLTCVAFAIFQERDILNTLMIPSKVFLAFMTTLEDHYVKDNPFHNSLHAADVAQSTHVLLNTPALENVFTPLETCAALFAACIHDVDHPGLTNQFLINSSSELAIMYNDESVLENHHLAVAFKLLQNEDCDILRNIQKKQRQTFRKMVIDMVLSTDMSKHMTLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPMYKRWVARLMEEFFLQGDKERAAGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDMLEENRDYYQSLIPPS 713
BLAST of Phosphodiesterase vs. TrEMBL
Match: F1QR03 (Phosphodiesterase (Fragment) OS=Danio rerio OX=7955 GN=pde4ca PE=3 SV=2) HSP 1 Score: 521.546 bits (1342), Expect = 8.873e-173 Identity = 282/625 (45.12%), Postives = 396/625 (63.36%), Query Frame = 3
Query: 174 GSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIP-IPKKDHINNLKDNFSNKKIRESKSFGGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFS---DIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISK----KSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
G+ P S K+ ++ + + + M S+ R+F + P D N L S + S GL +Q N SQRRESFLY+ + D +SP+ SR +S S+ ED+IVTPFAQ+LA L +R+N + + +++ + ++ C+ S + F+ A E++ LDWCL LE ++T SVS +A+ KFK+MLN EL Q ET SK+ +Q+S+YI +TFLE D D +S+ SK K P G +K N+ RFG+S + + E + W +D+F+I E S N LT+ Y F+ R ++++F IP D IN++ +E NY+S + YHNSIHAADV+Q+ +V+L + AL+ +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NLTK++R + RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y +W RIM EFF QGD+E++ G+++S MCD+ N++++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 1 GNSPTGSPKMSPRSSPRNSPLLFRRLMMN---RSIALQRRFTLAHTPSFDVENGLSVGRSPLDSQASPG-SGLVLQANFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELHG-----EDMIVTPFAQVLASLRTVRSNFA------VLTHQQDRVPSKKSTGNNPPSMCKTSLPEEPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSET---SKSGNQVSEYISSTFLEKQHDMD-----IMSTPSKEKEKKKRPMSQISGVKKPTHSSNIAPSSIPRFGVSTNREDLLAKELED-FDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWY 601
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A034VFR6 (Phosphodiesterase OS=Bactrocera dorsalis OX=27457 GN=PDE4D PE=3 SV=1) HSP 1 Score: 519.235 bits (1336), Expect = 1.391e-172 Identity = 264/560 (47.14%), Postives = 374/560 (66.79%), Query Frame = 3
Query: 381 GGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEK---ENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLE-------------DNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLD------KKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +QN QRRESFLY+ + D +SP+ SR +S+ S+ ED+IVTPFAQILA L +R N+ + ++ +++ + + QL + + S A +++ LDWCL LE IQT RSVS +A++KFK+MLN EL + E+ S++ +QIS+YIC+TFL+ DN D+ + + S S + P G ++ L + FG+ + + + ++TW ID+F+I ++S N LT V Y IF++R+++ + IP INF+ +E +Y K P+HNS+HAADV Q+ NV+L + AL+ +FT LE+ LFA IHDV HPG+TNQFL+N++ LA +YND+SVLENHHLA +F +++++ DI N+ K++R T RK VID+VL+TDMS+HM+LLADLKTMVETKKV+GSG+L +D Y DR+ +L+NLVHCADLSNPTKP +Y++WVS +MEEFFLQGDKE+E G+D+S MCDR N+ ++K+QVGFIDYIVHPLWE W +LVHPDA +L+TL ENR +Y
Sbjct: 38 AGLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASESHG-----EDLIVTPFAQILASLRSVRNNLLSLTNVQASNKRPTQSSSVGRASTAGVQL-VQGDESYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSES---SRSGNQISEYICSTFLDKQQELDLPSMRGDDNPDQHNMLTQHQRSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETVHENALGTLL-GDVDTWGIDIFKIGDLSANRPLTCVAYTIFQSRELLTSLMIPPKTFINFMTTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTSLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVSLLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 587
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346]) HSP 1 Score: 509.99 bits (1312), Expect = 1.457e-171 Identity = 265/547 (48.45%), Postives = 367/547 (67.09%), Query Frame = 3
Query: 384 GLQIQ---NNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q +SQRRESFLY+ + D +SP+ SR +S S+ ED+IVTPFAQ+LA L +R+N + + L+ + N + +L D + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE D + S KK P G +K +L RFG+S S + + E +N W +D+F+I E S N LT++ Y+IF+ R ++++F IP D I F++ +E +Y + + YHN+IHAADV+Q+ +V+L S AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NL+K++R + RK VIDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RIM E+F QGD+E++ G+++S MCD+ ++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 91 GLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELHG-----EDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLP---DDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTFLEKQHDVE-ILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 624
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346]) HSP 1 Score: 508.834 bits (1309), Expect = 2.961e-171 Identity = 266/556 (47.84%), Postives = 369/556 (66.37%), Query Frame = 3
Query: 384 GLQIQ---NNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNS-----AECV----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q +SQRRESFLY+ + D +SP+ SR +S S+ C+ ED+IVTPFAQ+LA L +R+N + + L+ + N + +L D + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE D + S KK P G +K +L RFG+S S + + E +N W +D+F+I E S N LT++ Y+IF+ R ++++F IP D I F++ +E +Y + + YHN+IHAADV+Q+ +V+L S AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NL+K++R + RK VIDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RIM E+F QGD+E++ G+++S MCD+ ++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 65 GLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLP---DDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTFLEKQHDVE-ILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 612
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346]) HSP 1 Score: 508.064 bits (1307), Expect = 4.005e-171 Identity = 266/556 (47.84%), Postives = 369/556 (66.37%), Query Frame = 3
Query: 384 GLQIQ---NNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNS-----AECV----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q +SQRRESFLY+ + D +SP+ SR +S S+ C+ ED+IVTPFAQ+LA L +R+N + + L+ + N + +L D + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE D + S KK P G +K +L RFG+S S + + E +N W +D+F+I E S N LT++ Y+IF+ R ++++F IP D I F++ +E +Y + + YHN+IHAADV+Q+ +V+L S AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NL+K++R + RK VIDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RIM E+F QGD+E++ G+++S MCD+ ++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 49 GLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLP---DDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTFLEKQHDVE-ILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 596
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346]) HSP 1 Score: 509.605 bits (1311), Expect = 4.298e-171 Identity = 266/556 (47.84%), Postives = 369/556 (66.37%), Query Frame = 3
Query: 384 GLQIQ---NNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNS-----AECV----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q +SQRRESFLY+ + D +SP+ SR +S S+ C+ ED+IVTPFAQ+LA L +R+N + + L+ + N + +L D + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE D + S KK P G +K +L RFG+S S + + E +N W +D+F+I E S N LT++ Y+IF+ R ++++F IP D I F++ +E +Y + + YHN+IHAADV+Q+ +V+L S AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NL+K++R + RK VIDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RIM E+F QGD+E++ G+++S MCD+ ++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 94 GLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLP---DDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTFLEKQHDVE-ILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 641
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346]) HSP 1 Score: 509.605 bits (1311), Expect = 5.049e-171 Identity = 266/556 (47.84%), Postives = 369/556 (66.37%), Query Frame = 3
Query: 384 GLQIQ---NNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNS-----AECV----EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK-----NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q +SQRRESFLY+ + D +SP+ SR +S S+ C+ ED+IVTPFAQ+LA L +R+N + + L+ + N + +L D + A E++ LDWCL LE +QT SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE D + S KK P G +K +L RFG+S S + + E +N W +D+F+I E S N LT++ Y+IF+ R ++++F IP D I F++ +E +Y + + YHN+IHAADV+Q+ +V+L S AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F +++++N DI +NL+K++R + RK VIDMVLATDMS+HMN LADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP IY +W RIM E+F QGD+E++ G+++S MCD+ ++V+K+QVGFIDYIVHPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 100 GLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLP---DDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFIASTFLEKQHDVE-ILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007435.1 (pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 gene:ENSPMAG00000006710.1 transcript:ENSPMAT00000007435.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 282.337 bits (721), Expect = 2.730e-91 Identity = 127/205 (61.95%), Postives = 166/205 (80.98%), Query Frame = 3
Query: 1302 SDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQ-VGFIDYIVHPLW 1913
S + Q +FTDLEI + +FA IHDV HPGV+NQFLINTN LA +YND+SVLENHHLA F +++++N DI +NL+K++R T RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ SG+L +D Y DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+++S MCD+ +++V+K+Q + ID+ +H W
Sbjct: 1 SPSPQAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLDVYRQWTERIMEEFFRQGDRERERGMEISPMCDKHSASVEKSQRINAIDFSLHCWW 205
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde4ba (phosphodiesterase 4B, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-030131-9570]) HSP 1 Score: 252.292 bits (643), Expect = 1.186e-77 Identity = 144/374 (38.50%), Postives = 218/374 (58.29%), Query Frame = 3
Query: 522 EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFR--AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRD---------DNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRFGIS--FTEASYINE--VFESSL-------NTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMV 1574
+D+IVTPFAQ+LA L +R N S + L+ + + T + ++ A E+M LDWCL LE +QT RSVS +A+ KFK+MLN EL E +S++ +Q+S++I +TF++ + + + L+S + A L + G+ A+ + +F +L N W I++F I E+S+N LT++ Y IF+ R++++TF IP D + +++ +E ++ + YHNS+HAADV Q+ +V+L S AL +FTDLEI + +FA IHDV HPGV+NQFLI+TN LA +YND+SVLENHHLA F ++++ N DI +NL K++R T RK VIDMV
Sbjct: 3 DDLIVTPFAQVLASLRSVRNNFSALTNLQGTPSRRSP----AGNQTSYPRAAPSDEGYQKLALETMEELDWCLDQLEAVQTHRSVSEMASNKFKRMLNRELSHLSE---MSRSGNQVSEFISSTFMDKQHEMEVPSAGHKEKERQRRPLASGGGVAAVGGAAPAVPSQLAAGVSHISGVQRLLHGAAILQRAMIFRDALSQELEDINKWGINIFRIAELSNNRPLTVLMYTIFQERELLKTFQIPADTFVTYMMTLEDHHAGVAYHNSLHAADVAQSTHVLLASPALDAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLGKKQRQTLRKMVIDMV 369
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007498.1 (pep scaffold:Pmarinus_7.0:GL486417:1684:4657:1 gene:ENSPMAG00000006774.1 transcript:ENSPMAT00000007498.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 218.779 bits (556), Expect = 1.010e-67 Identity = 95/139 (68.35%), Postives = 116/139 (83.45%), Query Frame = 3
Query: 1572 VLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
VLATDMS+HMNLL DLKT VETKKV+ SG+L +D Y DR+ +LQN+VHCADLSNPTKP +Y +W RIMEEFF QGD+E+E G+D+S MCDR +++V+K+QVGFIDYIVHPLWE W +LV PDA +L+TL ENR FY
Sbjct: 2 VLATDMSKHMNLLGDLKTTVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLGLYRQWTERIMEEFFQQGDRERERGIDISPMCDRHSASVEKSQVGFIDYIVHPLWETWADLVQPDAQEMLDTLEENRDFY 140
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776]) HSP 1 Score: 216.468 bits (550), Expect = 2.999e-63 Identity = 119/309 (38.51%), Postives = 177/309 (57.28%), Query Frame = 3
Query: 999 KKIFSRFGISFTEA--SYINEVFESSLNTWSIDLFEIHEIS-HNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSL--PYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIK-DKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHP 1907
++ S G+S+ A S + EV + WS D+F +HE S + L + Y +F +I F IP +++F+ +E Y PYHNS+HAADV QT + ++ + +LEI S++FA IHD H G TN F I T A LYND+SVLENHH++ ++ +++ D+ +IL NL+K + R V++ VLATDMS H + L +K LL + ++ + ++H AD+S+P K ++ +W +MEEFF QGDKE ELGL S +CDR + V ++Q+GFIDYIV P
Sbjct: 120 RRTSSMVGLSYPPAVISVLKEV-----DKWSFDVFALHEASGEHALKFIVYELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKNPYHNSVHAADVTQTVHYLMLKTGTIHWLNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFHQLKSIK-----------NLLQQPEGVEKPKAMSLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAELGLSFSPLCDRNATMVPQSQIGFIDYIVEP 412
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2]) HSP 1 Score: 213.001 bits (541), Expect = 3.837e-61 Identity = 112/314 (35.67%), Postives = 178/314 (56.69%), Query Frame = 3
Query: 1080 WSIDLFEIHEIS-HNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSL--PYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQ 2012
WS D+F ++E S + L V + + ++I + IP L++F+ +E Y PYHN HAADV QT + +L L + ++LE +V+FA IHD+ H G TN F I T +A LYND++VLENHH++ ++ +++D + +I NL+K + R V++MVLATDMS H + +K+ L + D+ + L+H D+S+PTK ++++W +MEEFF QGD+E +LGL S +CDR ++ V ++Q+GF+D+IV P + ++ A V+ LAE T P +
Sbjct: 153 WSFDVFVLNEASGEHALKFVMHELLTRYELISRYKIPVAALVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSA-----------LQQPESIDKSKAMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSPLCDRNSTMVAQSQIGFMDFIVEPTFSVLTDM----AEKVVVPLAEEAARAGTPGVPRR 451
BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887]) HSP 1 Score: 60.8474 bits (146), Expect = 4.048e-10 Identity = 48/186 (25.81%), Postives = 88/186 (47.31%), Query Frame = 3
Query: 1245 YHNSIHAADVIQT----ANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEF 1790
+HN HA DV+Q +L+ + +Q + + A + HDVGHPG NQ L N +A + + S+LEN H F + +++ L +++K++ + + +LATDM+ H + E + + + + ++T++ ++ AD+SN T+ I +W I EF
Sbjct: 264 FHNFRHAIDVMQATWRLCTYLLKDNPVQTLL-------LCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHREL-FQQLLSEHWPQLLSISKKKFDF----ISEAILATDMALH--------SQYEDRLMHENPM-------KQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO46133 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM4]) HSP 1 Score: 422.55 bits (1085), Expect = 8.679e-141 Identity = 233/548 (42.52%), Postives = 339/548 (61.86%), Query Frame = 3
Query: 408 QRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTC----EFSDIFR---AKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYS----DCLSSISKKSNPEDIADGKEKNLDKKIFS----RFGISFTEASYINEVFESSLNTWSIDLFEIHEIS--HNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVS--GSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKEL-GLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
QRRESFLYK + + ++P+ + + S+ + E +VTPFAQIL+ L +R + N D Q +C + S F A ++ LDW L LE +QT SVS +A+ KFK++LN EL + E +Q + +Q+S ++ TF + + + S DC+ + S+ + +G K FS RFG+ S + + E+ +N W D F + E + H +L V+Y I + R +++ F I IN++ +E +Y K +P+HN IHAADV QTA+V+L + A N+FTDLEI S + A +HDV HPGV N FL+ TN +A +YND+SVLENHHLA +F +++ ++ DI NL+KQER T R+ +I+MVLATD ++HM+LLA LKTMVETKKV+ GSG+L ++ Y DR+ +L++LVHCADLSNPTKP IY KWV R+MEEFF QGDKE+++ G+++S M DR N++++K+QV FID++ PLWE WGELV PDA +L+T+ +NR +Y
Sbjct: 1 QRRESFLYKSDSEFELAPKCVTSRHHSFSEGTRVEE-----LVTPFAQILSSLRNVRNTFVTLT--------------NAKKDKQFKHSCFCTSKCSHSFYSWVANSTLDELDWVLYQLETLQTHTSVSEMASNKFKRLLNRELKDFSEANQ---SGNQVSAWVYNTFTDKQLEVETAQSKTKRDCIRARSRS-----MVNGVRKLTRLHSFSGSVPRFGVEVQNESELATILEN-VNKWDFDAFALGEATNGHPMLA-VSYTILQARDLLKIFKIKPTTFINYMTLVENHYLKDVPFHNCIHAADVTQTAHVLLSAQAFDNVFTDLEILSAIIASAVHDVDHPGVNNHFLVATNSEMALMYNDESVLENHHLAVAFQLLQHEDCDIFENLSKQERQTARRMIIEMVLATDNAKHMSLLASLKTMVETKKVAGTGSGVLCLENYTDRMQVLKSLVHCADLSNPTKPLPIYRKWVDRLMEEFFRQGDKERDIDGMEISPMMDRHNASIEKSQVVFIDFVAQPLWETWGELVQPDAQDLLDTIEDNRQWY 519
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO37301 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGA1]) HSP 1 Score: 224.557 bits (571), Expect = 4.351e-67 Identity = 119/288 (41.32%), Postives = 173/288 (60.07%), Query Frame = 3
Query: 1080 WSIDLFEIHE-ISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYK--SLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELV 1934
W+ D+F + E + L + Y + R +++ F I L FL +E YK S PYHN HAADV T + L+ + +DLE+F +L + +IHD+ H G TN F IN+ LA LYND+SVLENHH++ +F I++D +IL L ++ + R +ID VLATDMS H L +K + V+GS + + + ++Q L+H AD+SNPTK I+ +W ++IMEEFF QGD E ELGLDVS +CDR + + ++Q+GFID+IV P E E++
Sbjct: 81 WTFDVFALSESCEGHPLRYIGYEVLHRRDMLRNFKIHAMTLDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIHDLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADVRSLMIDTVLATDMSSHFEQLRLMKVAL----VAGSPIENRE-------VVQLLLHVADISNPTKDWTIHRQWTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIPESQIGFIDFIVSPALEVCSEVL 357
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXZ4]) HSP 1 Score: 192.586 bits (488), Expect = 4.357e-55 Identity = 112/331 (33.84%), Postives = 167/331 (50.45%), Query Frame = 3
Query: 1080 WSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQ-----------------------------------TANVILQS-------------DALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTII-KDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWG 1925
W+ +F+ E N+L V+Y IF+N + F IP +N+ +E Y S+PYHNSIHA+DV+Q T+ V+ + AL ++ LE+ S+ A +HD HPG TN FL+ T H A LYND+SVLENHH A +FT++ D Y+ L L+ E FR I+ +LATD+ RH ++L+D + G ++ D DR+ LQ + +D+S P+K R I+ W RI+EEF+ QGD E+ G+ VS DR+ V + Q FI+++V PL+ ++
Sbjct: 26 WNFPIFDACE-HGNILVQVSYRIFQNAGFFEIFKIPERKFLNYFFALESGYHSIPYHNSIHASDVLQGVYFLTTAKIPGFCPPGTPQKLGDNESDSDSDSGITSGVLGEGEEDKKDDDGGGDYGALVDVIPLLELLSLYTAAAMHDYDHPGRTNAFLVATLSHQALLYNDRSVLENHHAAAAFTLLMSDPKYNFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNAK------TAEGGVNWDSEADRLLTLQFCIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERARGMAVSPYMDRQQPHVAQLQDSFINHLVAPLYNSYA 349
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVX8]) HSP 1 Score: 197.978 bits (502), Expect = 1.541e-53 Identity = 108/291 (37.11%), Postives = 163/291 (56.01%), Query Frame = 3
Query: 1080 WSIDLFEIHEIS-HNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTII-KDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSG------SGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLD-VSAMCDRENSAVDKTQVGFIDYIVHPLWEAW 1922
W D+ ++ + S H L + I ++ + NI D + N+L IE NY + YHNS HAADV+ V L + ++ + L+ + L A ++HDV HPG TN FL N LA LYND +VLE+HH A +F + +D +I NL +E T R+++IDMV+AT+M+RH L+ + ++ S S ++ +R I + L+ CAD++NP +PR + ++W RI EE+F Q D+EK GL V + DR V ++QV FIDY V L++AW
Sbjct: 523 WDFDILKLEKASNHRPLYFLGLKILNRFRVCEKLNISEDYVKNWLQLIEANYHRKNAYHNSTHAADVLHATAVFLAKERVKAVLEPLDEVASLIAAIVHDVDHPGYTNSFLCNAGSELAILYNDIAVLESHHAALAFKLTARDDKSNIFSNLDVEEFRTVRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSSSTPDSNTSTSTALNTPENRTLIKRMLIKCADIANPARPRYLCKEWAYRIAEEYFSQTDEEKRRGLPVVMPVFDRATCNVPRSQVWFIDYFVSDLYDAW 813
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVS5]) HSP 1 Score: 156.762 bits (395), Expect = 4.429e-41 Identity = 83/256 (32.42%), Postives = 139/256 (54.30%), Query Frame = 3
Query: 1164 IIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGEL 1931
++ F I L +FL ++ +Y P+HN HA V Q ++ + N T ++ +L + + HD+ HPG N + IN LA YND S LENHH A +F I+K +IL+N++ + R+ +I +L+TDM+RH ++L K ++++ D + ++Q ++ +D+SN +P + E W+ +++EFF+Q D EK GL V+ DR+ Q+GFI +++ PL+EA GEL
Sbjct: 197 LLDEFKIERSKLQHFLFEVYRHYNPTPFHNFRHAFCVTQMMYGLIWLTEIFNKITKQDLLIMLTSALCHDLDHPGYNNAYQINARTELALRYNDISPLENHHCAVAFDIMKQDKSNILQNVSAETFKKIREGMIKCILSTDMARHSDILNKFKELLKSG-------FKFDDEAHKSMLMQIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLEGLPVAPFMDRDKVTKPSAQIGFIKFVLVPLFEALGEL 445
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4ca (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:NCBI gene;Acc:101161266]) HSP 1 Score: 507.679 bits (1306), Expect = 9.224e-171 Identity = 265/544 (48.71%), Postives = 365/544 (67.10%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLT-CEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK---NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ +R S S S ED+IVTPFAQ+LA L +R N S + + D + + + N + + E D A E++ LDWCL LE ++T SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE + D D S K+ P G K +L RFG++ ++ + + E +N W ID+F++ E S LT+ Y+IF+ R +++TF IP DI INF++ +E +Y S + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F ++++ DI ++L+K++R + RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+++S MCD+ N++++K QVGFIDYI HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 73 GLVLQANFPHSQRRESFLYRSDSDFDLSPKGPTRNPS-----SASDLHSEDMIVTPFAQVLASLRTVRNNFSTITGQQ--DRTVSKMRSSNNPPSVSKTSLAEEPDQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFISSTFLEKSHDMD-IMSPPSKEKDKRKRPMSQISGVRKPTYSLAPSSIPRFGVNASQEGLLAKQLED-INRWGIDIFKVAEYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIHAADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQEDQCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWY 604
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4ca (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:NCBI gene;Acc:101161266]) HSP 1 Score: 504.597 bits (1298), Expect = 5.387e-170 Identity = 267/554 (48.19%), Postives = 368/554 (66.43%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSK--------ESN--SAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLT-CEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK---NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ +R S S E N S+ ED+IVTPFAQ+LA L +R N S + + D + + + N + + E D A E++ LDWCL LE ++T SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE + D D S K+ P G K +L RFG++ ++ + + E +N W ID+F++ E S LT+ Y+IF+ R +++TF IP DI INF++ +E +Y S + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F ++++ DI ++L+K++R + RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+++S MCD+ N++++K QVGFIDYI HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 29 GLVLQANFPHSQRRESFLYRSDSDFDLSPKGPTRNPSSASDLEESLKHWEVNWLSSRHSEDMIVTPFAQVLASLRTVRNNFSTITGQQ--DRTVSKMRSSNNPPSVSKTSLAEEPDQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFISSTFLEKSHDMD-IMSPPSKEKDKRKRPMSQISGVRKPTYSLAPSSIPRFGVNASQEGLLAKQLED-INRWGIDIFKVAEYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIHAADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQEDQCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWY 575
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4ca (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:NCBI gene;Acc:101161266]) HSP 1 Score: 505.753 bits (1301), Expect = 7.067e-170 Identity = 267/554 (48.19%), Postives = 368/554 (66.43%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSK--------ESN--SAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLT-CEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK---NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ +R S S E N S+ ED+IVTPFAQ+LA L +R N S + + D + + + N + + E D A E++ LDWCL LE ++T SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE + D D S K+ P G K +L RFG++ ++ + + E +N W ID+F++ E S LT+ Y+IF+ R +++TF IP DI INF++ +E +Y S + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F ++++ DI ++L+K++R + RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+++S MCD+ N++++K QVGFIDYI HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 73 GLVLQANFPHSQRRESFLYRSDSDFDLSPKGPTRNPSSASDLEESLKHWEVNWLSSRHSEDMIVTPFAQVLASLRTVRNNFSTITGQQ--DRTVSKMRSSNNPPSVSKTSLAEEPDQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFISSTFLEKSHDMD-IMSPPSKEKDKRKRPMSQISGVRKPTYSLAPSSIPRFGVNASQEGLLAKQLED-INRWGIDIFKVAEYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIHAADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQEDQCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWY 619
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4ca (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:NCBI gene;Acc:101161266]) HSP 1 Score: 504.982 bits (1299), Expect = 8.550e-170 Identity = 267/554 (48.19%), Postives = 368/554 (66.43%), Query Frame = 3
Query: 384 GLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSK--------ESN--SAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLT-CEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK---NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
GL +Q N SQRRESFLY+ + D +SP+ +R S S E N S+ ED+IVTPFAQ+LA L +R N S + + D + + + N + + E D A E++ LDWCL LE ++T SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE + D D S K+ P G K +L RFG++ ++ + + E +N W ID+F++ E S LT+ Y+IF+ R +++TF IP DI INF++ +E +Y S + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F ++++ DI ++L+K++R + RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+++S MCD+ N++++K QVGFIDYI HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 48 GLVLQANFPHSQRRESFLYRSDSDFDLSPKGPTRNPSSASDLEESLKHWEVNWLSSRHSEDMIVTPFAQVLASLRTVRNNFSTITGQQ--DRTVSKMRSSNNPPSVSKTSLAEEPDQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFISSTFLEKSHDMD-IMSPPSKEKDKRKRPMSQISGVRKPTYSLAPSSIPRFGVNASQEGLLAKQLED-INRWGIDIFKVAEYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIHAADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQEDQCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWY 594
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4ca (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:NCBI gene;Acc:101161266]) HSP 1 Score: 506.523 bits (1303), Expect = 1.637e-169 Identity = 273/587 (46.51%), Postives = 377/587 (64.22%), Query Frame = 3
Query: 288 RKFNIP-IPKKDHINNLKDNFSNKKIRESKSFGGLQIQNN---SQRRESFLYKYEEDSSISPERYSRQTSVLSK--------ESN--SAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLT-CEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEK---NLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHN-VLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKS-LPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFY 1988
R+F + P D N L + GL +Q N SQRRESFLY+ + D +SP+ +R S S E N S+ ED+IVTPFAQ+LA L +R N S + + D + + + N + + E D A E++ LDWCL LE ++T SVS +A+ KFK+MLN EL Q ET S++ +Q+S++I +TFLE + D D S K+ P G K +L RFG++ ++ + + E +N W ID+F++ E S LT+ Y+IF+ R +++TF IP DI INF++ +E +Y S + YHN+IHAADV+Q+ +V+L + AL+ +FTDLEI + LFA IHDV HPGV+NQFLINTN LA +YND SVLENHHLA F ++++ DI ++L+K++R + RK VIDMVLATDMS+HMNLLADLKTMVETKKV+ G+L +D Y+DR+ +LQN+VHCADLSNPTKP +Y KW RIM EFF QGD+E++ G+++S MCD+ N++++K QVGFIDYI HPLWE W +LVHPDA +L+TL +NR +Y
Sbjct: 82 RRFTLAHTPSFDVENGLSAGRGGPIDAQVNPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKGPTRNPSSASDLEESLKHWEVNWLSSRHSEDMIVTPFAQVLASLRTVRNNFSTITGQQ--DRTVSKMRSSNNPPSVSKTSLAEEPDQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSET---SRSGNQVSEFISSTFLEKSHDMD-IMSPPSKEKDKRKRPMSQISGVRKPTYSLAPSSIPRFGVNASQEGLLAKQLED-INRWGIDIFKVAEYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIHAADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQEDQCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWY 661
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000056509.1 (SMESG000056509.1) HSP 1 Score: 1328.54 bits (3437), Expect = 0.000e+0 Identity = 641/643 (99.69%), Postives = 642/643 (99.84%), Query Frame = 3
Query: 93 MDSNVRVRSLSSCELFMHQMLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT 2021
MDSNVRVRSLSSCELFMHQMLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCL NLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSIS+KSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT
Sbjct: 1 MDSNVRVRSLSSCELFMHQMLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLTNLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISRKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT 643
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000056509.1 (SMESG000056509.1) HSP 1 Score: 1296.57 bits (3354), Expect = 0.000e+0 Identity = 625/627 (99.68%), Postives = 626/627 (99.84%), Query Frame = 3
Query: 141 MHQMLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT 2021
MHQMLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCL NLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSIS+KSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT
Sbjct: 1 MHQMLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLTNLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISRKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT 627
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000056509.1 (SMESG000056509.1) HSP 1 Score: 1289.25 bits (3335), Expect = 0.000e+0 Identity = 622/624 (99.68%), Postives = 623/624 (99.84%), Query Frame = 3
Query: 150 MLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISKKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT 2021
MLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCL NLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSIS+KSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT
Sbjct: 1 MLYNRKRMGSLPLTSKKVKDKNDSEMNACFIKHVPMKLTRNSLTNSRKFNIPIPKKDHINNLKDNFSNKKIRESKSFGGLQIQNNSQRRESFLYKYEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKENDIHLNENIDTQLNLTCEFSDIFRAKESMYMLDWCLTNLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLEDNFDRDDNYSDCLSSISRKSNPEDIADGKEKNLDKKIFSRFGISFTEASYINEVFESSLNTWSIDLFEIHEISHNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNYKSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTCPSQTIT 624
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000032148.1 (SMESG000032148.1) HSP 1 Score: 527.709 bits (1358), Expect = 3.143e-180 Identity = 286/590 (48.47%), Postives = 394/590 (66.78%), Query Frame = 3
Query: 384 GLQIQNNSQRRESFLYK-YEEDSSISPERYSRQTSVLSKESNSAECVEDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKE-NDIHLNENIDTQLNLTCEFSDIFRA--KESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLE----DNFDRDDNYSDC-----------LSSISKKSNPEDIADGKEKNLD-------------KKIF------SRFGISFTEASYINEVFESSLNTWSIDLFEIHEIS-HNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTKTC------PSQT 2015
GL + + QRRESFLY+ + D S SP R SR S+ E ++ +D+IVTPFAQILA L +RAN + ++ E I + + +L E D R+ E++ L+WCL LE++QT RSVS +A+ KFKK+LN EL QY DQ SK+ +QISDYICTTFL+ ++ D+ Y D L S+ E ADG + K IF S FGI+ T + E+ E++L+TW +D+F + +S +N LT++++A+F+ ++ + F+I + I ++F+ +IE Y K +PYHNS HAADV Q+ NV+L + +L+N+F+DLEI +V+FAC+IHDV HPGVTNQ+LINTND LA +YND SVLENHHL+ +FT++ N DI+ NLTK++R +FRK VIDMVLATDMS+HM+LLADLKTMVETKKV+GSG+L++D YNDR+ ILQN+VHCADLSNPTKP +Y W +IM+EFF QGDKE+E L++S MCDRE + V+K+QV FID+IVHPLWE W +LV+P+A +L+TL +NR +YF++ PS+T
Sbjct: 27 GLVLHHIPQRRESFLYRGIDTDFSPSP-RSSRHASIAFGEPHAFAHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQY--ADQ-SKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSET 612
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000032148.1 (SMESG000032148.1) HSP 1 Score: 506.138 bits (1302), Expect = 1.083e-170 Identity = 264/531 (49.72%), Postives = 364/531 (68.55%), Query Frame = 3
Query: 522 EDIIVTPFAQILAVLHRIRANVSEMPQLKLYDEKE-NDIHLNENIDTQLNLTCEFSDIFRA--KESMYMLDWCLANLENIQTDRSVSSLATVKFKKMLNFELHQYDETDQVSKADHQISDYICTTFLE----DNFDRDDNYSDC-----------LSSISKKSNPEDIADGKEKNLD-------------KKIF------SRFGISFTEASYINEVFESSLNTWSIDLFEIHEIS-HNVLTLVTYAIFKNRQIIQTFNIPNDILINFLLKIEVNY-KSLPYHNSIHAADVIQTANVILQSDALQNIFTDLEIFSVLFACVIHDVGHPGVTNQFLINTNDHLATLYNDQSVLENHHLATSFTIIKDKNYDILRNLTKQERSTFRKSVIDMVLATDMSRHMNLLADLKTMVETKKVSGSGLLDMDKYNDRVTILQNLVHCADLSNPTKPRVIYEKWVSRIMEEFFLQGDKEKELGLDVSAMCDRENSAVDKTQVGFIDYIVHPLWEAWGELVHPDAHSVLETLAENRYFYFTK 1997
+D+IVTPFAQILA L +RAN + ++ E I + + +L E D R+ E++ L+WCL LE++QT RSVS +A+ KFKK+LN EL QY DQ SK+ +QISDYICTTFL+ ++ D+ Y D L S+ E ADG + K IF S FGI+ T + E+ E++L+TW +D+F + +S +N LT++++A+F+ ++ + F+I + I ++F+ +IE Y K +PYHNS HAADV Q+ NV+L + +L+N+F+DLEI +V+FAC+IHDV HPGVTNQ+LINTND LA +YND SVLENHHL+ +FT++ N DI+ NLTK++R +FRK VIDMVLATDMS+HM+LLADLKTMVETKKV+GSG+L++D YNDR+ ILQN+VHCADLSNPTKP +Y W +IM+EFF QGDKE+E L++S MCDRE + V+K+QV FID+IVHPLWE W +LV+P+A +L+TL +NR +YF++
Sbjct: 155 DDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQY--ADQ-SKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQ 682 The following BLAST results are available for this feature:
BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30032008 ID=SMED30032008|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=2145bpback to top protein sequence of SMED30032008-orf-1 >SMED30032008-orf-1 ID=SMED30032008-orf-1|Name=SMED30032008-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=660bp MDSNVRVRSLSSCELFMHQMLYNRKRMGSLPLTSKKVKDKNDSEMNACFIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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