STAS domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031995 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of STAS domain-containing protein vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359]) HSP 1 Score: 183.726 bits (465), Expect = 2.041e-50 Identity = 119/345 (34.49%), Postives = 187/345 (54.20%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL---------EEMENTDL--------------IAKRAVFQEELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV-----RRMFYRIETSQLIHDENIFVSVHDAVINS 1301
+E IA GL N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LG++ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E++ D I ++ F EE+ + P N+H +I+D + +ID VGVK L +++EY +V I V LA V R F+ E L E +F S+HDAV+ S
Sbjct: 336 QELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF--ENPALW--ELLFHSIHDAVLGS 676 HSP 2 Score: 84.3445 bits (207), Expect = 1.190e-16 Identity = 49/122 (40.16%), Postives = 70/122 (57.38%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +L YNV VVGT+ G
Sbjct: 167 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLG 287
BLAST of STAS domain-containing protein vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359]) HSP 1 Score: 183.726 bits (465), Expect = 2.579e-50 Identity = 119/345 (34.49%), Postives = 187/345 (54.20%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL---------EEMENTDL--------------IAKRAVFQEELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV-----RRMFYRIETSQLIHDENIFVSVHDAVINS 1301
+E IA GL N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LG++ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E++ D I ++ F EE+ + P N+H +I+D + +ID VGVK L +++EY +V I V LA V R F+ E L E +F S+HDAV+ S
Sbjct: 373 QELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF--ENPALW--ELLFHSIHDAVLGS 713 HSP 2 Score: 84.3445 bits (207), Expect = 1.266e-16 Identity = 49/122 (40.16%), Postives = 70/122 (57.38%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +L YNV VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359]) HSP 1 Score: 182.956 bits (463), Expect = 5.203e-50 Identity = 119/347 (34.29%), Postives = 187/347 (53.89%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL-----------EEMENTDL--------------IAKRAVFQEELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV-----RRMFYRIETSQLIHDENIFVSVHDAVINS 1301
+E IA GL N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LG++ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E++ D I ++ F EE+ + P N+H +I+D + +ID VGVK L +++EY +V I V LA V R F+ E L E +F S+HDAV+ S
Sbjct: 373 QELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKATQDAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF--ENPALW--ELLFHSIHDAVLGS 715 HSP 2 Score: 84.3445 bits (207), Expect = 1.213e-16 Identity = 49/122 (40.16%), Postives = 70/122 (57.38%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +L YNV VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359]) HSP 1 Score: 182.956 bits (463), Expect = 5.203e-50 Identity = 119/347 (34.29%), Postives = 187/347 (53.89%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL-----------EEMENTDL--------------IAKRAVFQEELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV-----RRMFYRIETSQLIHDENIFVSVHDAVINS 1301
+E IA GL N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LG++ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E++ D I ++ F EE+ + P N+H +I+D + +ID VGVK L +++EY +V I V LA V R F+ E L E +F S+HDAV+ S
Sbjct: 373 QELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKATQDAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF--ENPALW--ELLFHSIHDAVLGS 715 HSP 2 Score: 84.3445 bits (207), Expect = 1.213e-16 Identity = 49/122 (40.16%), Postives = 70/122 (57.38%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +L YNV VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359]) HSP 1 Score: 178.333 bits (451), Expect = 1.241e-48 Identity = 107/313 (34.19%), Postives = 173/313 (55.27%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL---------EEMENTDL--------------IAKRAVFQEELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRR 1220
+E IA GL N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LG++ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E++ D I ++ F EE+ + P N+H +I+D + +ID VGVK L +++EY +V I V LA ++R
Sbjct: 373 QELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAFIQR 685 HSP 2 Score: 84.3445 bits (207), Expect = 1.092e-16 Identity = 49/122 (40.16%), Postives = 70/122 (57.38%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +L YNV VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. Ensembl Celegans
Match: sulp-6 (SULfate Permease family [Source:UniProtKB/TrEMBL;Acc:O45016]) HSP 1 Score: 167.162 bits (422), Expect = 1.305e-44 Identity = 108/345 (31.30%), Postives = 188/345 (54.49%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXG-PLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEE----------MENTDLIAKRAVFQEELDSLLNPN-------IHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHD---ENIFVSVHDAVINSLYDHKIQIECL 1334
+E+ A GLM+ SSFF C+ S+ R+ +Q G K+Q+++L++ I+++ + Q LP +LAS+++VA+K + ++ L S D+ ++ TF+ I L+V +GL+ GV ++++VLR+Q +S +LG+I+GT+ Y+ + +Y ++IPGIKIFR++ IY+ + F + ++ +P++V+ ++ KK + EE ++ +A +E + PN + HIIIDCST Y+D++G L V +YK + ISVL AN VR+ F ETSQ + +FVSV DAV + + + + E +
Sbjct: 399 QEWFALGLMHTTSSFFGCFAGGSSLGRTMMQVKCGTKSQLSTLITSIVLIIFVCGGAVGCIQHLPKPVLASIVVVAMKDLFIQIFTCFALRKLSFVDYLIFAATFISVIVLNVNFGLLIGVVFELLTVVLRSQWADSSLLGRITGTNHYRRLGLYETANDIPGIKIFRFDSPIYFGNSEMFVRKIHQACGLNPLIVRGELETENKKKDARKEKEEEDAEIPKETEKETKLEVTTHQAKVLDEKHAEPEPNPADQYERLTHIIIDCSTIIYVDLMGQGALKDVYNDYKTIGISVLFANTNEHVRQNF---ETSQFFEEVPRGRMFVSVSDAVDQAELEQRHKTETV 740 HSP 2 Score: 53.9138 bits (128), Expect = 1.686e-7 Identity = 36/126 (28.57%), Postives = 71/126 (56.35%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVT-IAKYYGIFSVWNTLIAVC--KQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQY-LDLHNKYNVSVVGTIIQG 366
+LSD L+ G G+A+ V ++QLK ++ + F N + +C KQ+P+ + + +++ I ++LL ++ VI+P L KK+ P+EL++VV+ T++ Y + ++ + VG + G
Sbjct: 227 WLSDQLVQGLISGAAVHVLTSQLKSMTRISNVPPTSEPFQ--NVVFYMCFFKQMPDVDYASIIISVICVVLLLISTLVIDPWLCKKVPVKFPMELVLVVSMTLTVHYTRNTAYEFQIPTVGQVTSG 350
BLAST of STAS domain-containing protein vs. Ensembl Celegans
Match: sulp-6 (SULfate Permease family [Source:UniProtKB/TrEMBL;Acc:O45016]) HSP 1 Score: 167.162 bits (422), Expect = 1.305e-44 Identity = 108/345 (31.30%), Postives = 188/345 (54.49%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXG-PLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEE----------MENTDLIAKRAVFQEELDSLLNPN-------IHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHD---ENIFVSVHDAVINSLYDHKIQIECL 1334
+E+ A GLM+ SSFF C+ S+ R+ +Q G K+Q+++L++ I+++ + Q LP +LAS+++VA+K + ++ L S D+ ++ TF+ I L+V +GL+ GV ++++VLR+Q +S +LG+I+GT+ Y+ + +Y ++IPGIKIFR++ IY+ + F + ++ +P++V+ ++ KK + EE ++ +A +E + PN + HIIIDCST Y+D++G L V +YK + ISVL AN VR+ F ETSQ + +FVSV DAV + + + + E +
Sbjct: 399 QEWFALGLMHTTSSFFGCFAGGSSLGRTMMQVKCGTKSQLSTLITSIVLIIFVCGGAVGCIQHLPKPVLASIVVVAMKDLFIQIFTCFALRKLSFVDYLIFAATFISVIVLNVNFGLLIGVVFELLTVVLRSQWADSSLLGRITGTNHYRRLGLYETANDIPGIKIFRFDSPIYFGNSEMFVRKIHQACGLNPLIVRGELETENKKKDARKEKEEEDAEIPKETEKETKLEVTTHQAKVLDEKHAEPEPNPADQYERLTHIIIDCSTIIYVDLMGQGALKDVYNDYKTIGISVLFANTNEHVRQNF---ETSQFFEEVPRGRMFVSVSDAVDQAELEQRHKTETV 740 HSP 2 Score: 53.9138 bits (128), Expect = 1.686e-7 Identity = 36/126 (28.57%), Postives = 71/126 (56.35%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVT-IAKYYGIFSVWNTLIAVC--KQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQY-LDLHNKYNVSVVGTIIQG 366
+LSD L+ G G+A+ V ++QLK ++ + F N + +C KQ+P+ + + +++ I ++LL ++ VI+P L KK+ P+EL++VV+ T++ Y + ++ + VG + G
Sbjct: 227 WLSDQLVQGLISGAAVHVLTSQLKSMTRISNVPPTSEPFQ--NVVFYMCFFKQMPDVDYASIIISVICVVLLLISTLVIDPWLCKKVPVKFPMELVLVVSMTLTVHYTRNTAYEFQIPTVGQVTSG 350
BLAST of STAS domain-containing protein vs. Ensembl Celegans
Match: sulp-4 (Anion transporter SULP-4; SULfate Permease family [Source:UniProtKB/TrEMBL;Acc:G5EEA7]) HSP 1 Score: 142.51 bits (358), Expect = 2.371e-36 Identity = 90/289 (31.14%), Postives = 153/289 (52.94%), Query Frame = 3
Query: 432 SVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSL---YTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDA 1289
S+SR+ V AG TQ++ S +++ V++F+G L + LP L+++I VAL+ M KF +L +LW S DF++W+V+ + TI LDV GLI V ++ + +LR Q P H+L + GT +++ YG+ GI IFR++ + + + FKKS+ YT+ LR ++ K++ S E ++ ++ +L+ H +IDCS + +ID++GV L ++ + + I V AN K VR MF + + EN + ++ DA
Sbjct: 430 SLSRTLVAVGAGCTTQLSIFFSSLIVFSVVIFLGTLLETLPMAALSAIICVALQGMFRKFADLIDLWKVSKIDFTIWVVSCVSTILLDVSTGLIISVCFALFTTILREQYPKWHLLASVKGTQDFRDAERYGETVYFKGICIFRFDAPLLFHNVECFKKSIEKAYTEWQKSHEFYVLREERETILNTKLDGSDESIDGKMFQTAQSTLNTHSPDILS---RHFVIDCSGFTFIDLMGVSALKEIFSDMRKRGILVYFANAKAPVREMFEKCHFFNFVSKENFYPTMRDA 715 HSP 2 Score: 59.6918 bits (143), Expect = 2.792e-9 Identity = 42/125 (33.60%), Postives = 68/125 (54.40%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVT-IAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKI--HFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSD +I+GFTVGS++ V +QLK G+ + ++ G F ++ L + + N + ++ +SII+L K INP + +K + PIP EL++V+ TV + + V VV I G
Sbjct: 234 YLSDQVIAGFTVGSSVHVLVSQLKTLLGIRGLPRHSGPFYLFRHLYDLVMSITRANPVSCGISIVSIIVLHFGKEFINPFIKRKTKSNIPIPWELVIVILSTVFVAVTGVDTEAKVQVVNKIPVG 358
BLAST of STAS domain-containing protein vs. Ensembl Celegans
Match: sulp-2 (Anion transporter SULP-2; SULfate Permease family [Source:UniProtKB/TrEMBL;Acc:G5EDS5]) HSP 1 Score: 141.354 bits (355), Expect = 4.491e-36 Identity = 99/331 (29.91%), Postives = 169/331 (51.06%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENI-----FVSVHDAVINS---LYDHKIQIEC 1331
+E +A G +NI SSFF +P++ S SR+ V E +G KTQ++ + S + V+ IGP LP+CIL++++IV L+SML K L LW S DF +W++T + T+ D+ G+ AG+ +I +I +++Q P +LGQI D ++ + Y E +I R++ + +A + F ++ S K R + S + E+ + A II+DC TW Y D +G+ + Q+ EE + + I +L AN K+ +RR + + LI + NI + S+ DA+ ++ + +HK+ +C
Sbjct: 349 QELLALGFINIGSSFFSVFPTSASFSRTLVNERSGAKTQLSGITSACFMALVITTIGPYLASLPSCILSAIVIVVLESMLRKCTVLPGLWRCSKHDFWIWIITAVVTLSSDIAQGVAAGIFTAIFTIAIQSQQPTIKLLGQIRPND-FRPMNHYSLAKET-SFRIIRFDAPLIFANVEKFLDNVRDSTS---ATTKKR-----------SASCDSQEDIEWSA-------------------IILDCHTWIYTDSMGIAAVKQINEELRQIRILLLFANLKSSLRRQY---GNAGLIGEGNIGRNQMYPSIQDALDSAHELIKNHKMFFDC 641
BLAST of STAS domain-containing protein vs. Ensembl Celegans
Match: sulp-3 (Sulfate permease family protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q94225]) HSP 1 Score: 141.739 bits (356), Expect = 4.685e-36 Identity = 90/313 (28.75%), Postives = 160/313 (51.12%), Query Frame = 3
Query: 357 YTREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPG-IKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAV 1292
+ +E A G + + SSFF +P +RS V A GG TQ+T L S + +L V+L IGP + LP CIL+++II A K ML KF ELK LW DF++W+++F T+ D+ GL+ + ++++ ++RTQ P H L + T+ YK D I G + IFR + + + D F S++ + + + + + + ++ ++ L + R ++ + S N ++IDC + Y+D +G+ L V + + I K+D++++F + +++ + +F V DAV
Sbjct: 392 HGQELYALGFVGVLSSFFPVFPVTSGFARSVVGAAVGGSTQLTCLFSSLALLSVILCIGPALEYLPQCILSAMIIFAQKGMLEKFGELKSLWPVFKIDFTIWLMSFFLTVCYDMGEGLLMAIGFAVLTTIIRTQRPKWHFLSRDDDTENYKETKKR-DLERIQGNVCIFRMDAPLIFTSSDRFTMSVWQCVKK---WERCKSESFVTIEQMNSDRSADIFDSKLKSARRRWKRDQKS---ENRCKLVIDCDGFPYVDYLGLSTLKSVYVDLQAAGIQCFFVVQKSDLKKLFRATDFYEVVDESKVFNKVGDAV 697 HSP 2 Score: 67.3958 bits (163), Expect = 1.152e-11 Identity = 36/118 (30.51%), Postives = 64/118 (54.24%), Query Frame = 1
Query: 4 LSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTI 357
S+ ++SGF VG I VF Q+ G+ + + G ++ + + + L N +IPT ++ S + L K + P L ++P+P EL++VV G ++ Y +L +++V VVG I
Sbjct: 225 FSEQVMSGFVVGGGIHVFFAQIGNMLGIELPRRSGPGYLYYRIWDLVENLDNVHIPTVCISLSSFLFLVFGKEYLAPWLNSAFNYPVPFELVLVVVGITATNYAELSLRHDVKVVGNI 342
BLAST of STAS domain-containing protein vs. Ensembl Fly
Match: Prestin (gene:FBgn0036770 transcript:FBtr0075153) HSP 1 Score: 125.561 bits (314), Expect = 1.058e-49 Identity = 97/314 (30.89%), Postives = 164/314 (52.23%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQIS-GTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPI-MVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDE--NIFVSVHDAV 1292
+E A G+ N+ F C P A S+SRS +Q+ GG +QI SLVS L++ L++IGP F LP C+LA VIIVALK M M+ ELK+ + W+ TFL + +D+ GL+ G+ +S++++ ++ P S +LG + +Y ++ + + ++P ++IFRY GS+ +A F+++LY + D I + K+ K S + A +E + +++D S G+ID+ G + L + +E K +LLA+P V R++ + S + + IF ++HD V
Sbjct: 428 QELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAF-----KVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASP---VDRVYDTLVHSMALSEGPFEIFPTLHDCV 733 HSP 2 Score: 91.6633 bits (226), Expect = 1.058e-49 Identity = 49/131 (37.40%), Postives = 77/131 (58.78%), Query Frame = 1
Query: 4 LSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG----NLSRLD 384
LS+PL++GFT +A V + QLK G+++ ++ G F + T+I V K +P TN+ F I + + ++ P L KK FP+P EL++V+ GT+ S++ +L+ YNV+ VG I G L RLD
Sbjct: 259 LSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLD 389
BLAST of STAS domain-containing protein vs. Ensembl Fly
Match: CG6125 (gene:FBgn0038337 transcript:FBtr0083106) HSP 1 Score: 79.337 bits (194), Expect = 2.174e-15 Identity = 53/178 (29.78%), Postives = 97/178 (54.49%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACK 893
++E + GL NI SFF P+ G+ +RSAV +A+G +T + + + +++L L + P FQ +P L++V+I A+ M+ +KELW + DF W+ +F+ + V+ GL+ G+ LS++ I+LR +P + + + Y ++ D + G+ R E + AC+
Sbjct: 382 SQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMI-DLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILLRLGNPKFEVTLKQHESTYYVHIVPQSDVYYT-GVDALRSE--LRGACR 555
BLAST of STAS domain-containing protein vs. Ensembl Fly
Match: CG6125 (gene:FBgn0038337 transcript:FBtr0346109) HSP 1 Score: 78.9518 bits (193), Expect = 2.246e-15 Identity = 53/178 (29.78%), Postives = 97/178 (54.49%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACK 893
++E + GL NI SFF P+ G+ +RSAV +A+G +T + + + +++L L + P FQ +P L++V+I A+ M+ +KELW + DF W+ +F+ + V+ GL+ G+ LS++ I+LR +P + + + Y ++ D + G+ R E + AC+
Sbjct: 353 SQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMI-DLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILLRLGNPKFEVTLKQHESTYYVHIVPQSDVYYT-GVDALRSE--LRGACR 526
BLAST of STAS domain-containing protein vs. Ensembl Fly
Match: CG6125 (gene:FBgn0038337 transcript:FBtr0083105) HSP 1 Score: 78.9518 bits (193), Expect = 2.246e-15 Identity = 53/178 (29.78%), Postives = 97/178 (54.49%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACK 893
++E + GL NI SFF P+ G+ +RSAV +A+G +T + + + +++L L + P FQ +P L++V+I A+ M+ +KELW + DF W+ +F+ + V+ GL+ G+ LS++ I+LR +P + + + Y ++ D + G+ R E + AC+
Sbjct: 353 SQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMI-DLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILLRLGNPKFEVTLKQHESTYYVHIVPQSDVYYT-GVDALRSE--LRGACR 526
BLAST of STAS domain-containing protein vs. Ensembl Fly
Match: CG6928 (gene:FBgn0036240 transcript:FBtr0076049) HSP 1 Score: 66.6254 bits (161), Expect = 2.215e-11 Identity = 46/135 (34.07%), Postives = 74/135 (54.81%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSP 764
TRE +A + NI +F P GS SRSAV A+G +T + + +L+L L + P FQ +P L++VII A+ M+ +F +K LW S + +TF+ ++ + V+ GL+ GV+ + +V R P
Sbjct: 324 TRELVALSMSNICGAFCSSMPVTGSFSRSAVNHASGVRTPLGGCYTSVLVLLALGLLAPYFQYIPKAALSAVIISAVIFMI-EFEVIKPLWRCSRRELLPGAITFVMSLAVGVEIGLLLGVSTDVAFLVYRAARP 457
BLAST of STAS domain-containing protein vs. Ensembl Zebrafish
Match: slc26a10 (solute carrier family 26 member 10 [Source:ZFIN;Acc:ZDB-GENE-030131-9845]) HSP 1 Score: 186.037 bits (471), Expect = 1.190e-51 Identity = 97/311 (31.19%), Postives = 182/311 (58.52%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVI 1295
+E +A G+ N SS F C+P++ +++ + + E+AGG TQ+ L + +++L VLL IGPLF LP +LA + + +L+ M ++F +L ELW S DF VW+VT+L + L+V GL G+ S++++V RTQ + +LG+ + T++Y+++ + C+E+PG+KI Y G IYY + FK + + P ++ R + ++ K+ +++ +E + F + D + + ++IDCS+ ++DI G ++ Q+ E + + + + LAN V ++ ++ ++IFV++HDAV+
Sbjct: 349 QELLAHGISNTVSSLFTCFPNSATLATTNILESAGGHTQLAGLFTSLVVLIVLLLIGPLFYFLPKAVLACINVTSLRQMFLQFQDLPELWRISKIDFMVWLVTWLSVVVLNVDLGLAIGMVFSMMTVVCRTQRASCSVLGRAANTEIYRSINNHNKCYEVPGVKILTYNGPIYYGNRSFFKADMAQLLGLTPERIRSREKALKAIEKREREAISTVEQG---VADSSFSSKNDLFTSGEVQAVLIDCSSVIFVDIAGARLFIQMCMECQKIGVRIYLANCNESVLKILTSSGLMNYMNPQHIFVTIHDAVV 656 HSP 2 Score: 63.929 bits (154), Expect = 2.424e-10 Identity = 31/95 (32.63%), Postives = 58/95 (61.05%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVV 285
YLS+P++ FT +A V +QL+ G+ + +Y G FS++ TL +V + +P+TN+ V++ + + +L K V N +++ PIP+E++ V
Sbjct: 192 YLSEPIVKAFTSAAAFHVTVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNLAELVISLLCLAVLVPVKEV-NSRFRERLRTPIPVEIITV 285
BLAST of STAS domain-containing protein vs. Ensembl Zebrafish
Match: slc26a10 (solute carrier family 26 member 10 [Source:ZFIN;Acc:ZDB-GENE-030131-9845]) HSP 1 Score: 186.037 bits (471), Expect = 1.190e-51 Identity = 97/311 (31.19%), Postives = 182/311 (58.52%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVI 1295
+E +A G+ N SS F C+P++ +++ + + E+AGG TQ+ L + +++L VLL IGPLF LP +LA + + +L+ M ++F +L ELW S DF VW+VT+L + L+V GL G+ S++++V RTQ + +LG+ + T++Y+++ + C+E+PG+KI Y G IYY + FK + + P ++ R + ++ K+ +++ +E + F + D + + ++IDCS+ ++DI G ++ Q+ E + + + + LAN V ++ ++ ++IFV++HDAV+
Sbjct: 349 QELLAHGISNTVSSLFTCFPNSATLATTNILESAGGHTQLAGLFTSLVVLIVLLLIGPLFYFLPKAVLACINVTSLRQMFLQFQDLPELWRISKIDFMVWLVTWLSVVVLNVDLGLAIGMVFSMMTVVCRTQRASCSVLGRAANTEIYRSINNHNKCYEVPGVKILTYNGPIYYGNRSFFKADMAQLLGLTPERIRSREKALKAIEKREREAISTVEQG---VADSSFSSKNDLFTSGEVQAVLIDCSSVIFVDIAGARLFIQMCMECQKIGVRIYLANCNESVLKILTSSGLMNYMNPQHIFVTIHDAVV 656 HSP 2 Score: 63.929 bits (154), Expect = 2.424e-10 Identity = 31/95 (32.63%), Postives = 58/95 (61.05%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVV 285
YLS+P++ FT +A V +QL+ G+ + +Y G FS++ TL +V + +P+TN+ V++ + + +L K V N +++ PIP+E++ V
Sbjct: 192 YLSEPIVKAFTSAAAFHVTVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNLAELVISLLCLAVLVPVKEV-NSRFRERLRTPIPVEIITV 285
BLAST of STAS domain-containing protein vs. Ensembl Zebrafish
Match: slc26a10 (solute carrier family 26 member 10 [Source:ZFIN;Acc:ZDB-GENE-030131-9845]) HSP 1 Score: 185.652 bits (470), Expect = 1.906e-51 Identity = 98/315 (31.11%), Postives = 185/315 (58.73%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEME----NTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVI 1295
+E +A G+ N SS F C+P++ +++ + + E+AGG TQ+ L + +++L VLL IGPLF LP +LA + + +L+ M ++F +L ELW S DF VW+VT+L + L+V GL G+ S++++V RTQ + +LG+ + T++Y+++ + C+E+PG+KI Y G IYY + FK + + P ++ R + ++ K+ +++ +E ++ +K +F E+ + ++IDCS+ ++DI G ++ Q+ E + + + + LAN V ++ ++ ++IFV++HDAV+
Sbjct: 361 QELLAHGISNTVSSLFTCFPNSATLATTNILESAGGHTQLAGLFTSLVVLIVLLLIGPLFYFLPKAVLACINVTSLRQMFLQFQDLPELWRISKIDFMVWLVTWLSVVVLNVDLGLAIGMVFSMMTVVCRTQRASCSVLGRAANTEIYRSINNHNKCYEVPGVKILTYNGPIYYGNRSFFKADMAQLLGLTPERIRSREKALKAIEKREREAISTVEQGVADSSFSSKNDLFTSEMA---EGEVQAVLIDCSSVIFVDIAGARLFIQMCMECQKIGVRIYLANCNESVLKILTSSGLMNYMNPQHIFVTIHDAVV 672 HSP 2 Score: 76.6406 bits (187), Expect = 1.909e-14 Identity = 39/122 (31.97%), Postives = 72/122 (59.02%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+P++ FT +A V +QL+ G+ + +Y G FS++ TL +V + +P+TN+ V++ + + +L K V N +++ PIP+E++ V+ T + L +KY++ +VG I G
Sbjct: 192 YLSEPIVKAFTSAAAFHVTVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNLAELVISLLCLAVLVPVKEV-NSRFRERLRTPIPVEIITVIIATGITYAFSLDSKYDIQIVGHIPAG 312
BLAST of STAS domain-containing protein vs. Ensembl Zebrafish
Match: slc26a3.1 (solute carrier family 26 member 3 [Source:ZFIN;Acc:ZDB-GENE-041210-180]) HSP 1 Score: 166.007 bits (419), Expect = 3.373e-44 Identity = 109/350 (31.14%), Postives = 187/350 (53.43%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMV--KLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEE--LDSLLNP-------------------------NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDE---NIF-VSVHDAVINSLYDH 1313
+E IAFG+ N+F + F + ++ ++SR+A+QE+ GGKTQI ++S +++L V++ +G L +PLP +L +++IV LK MLM+F EL LW DF WMVTF+ ++FL + GL G+ + ++V RTQ P +L ISGTDLY++ Y +E G+KIF+ I++A D F+ L ++ ++P+ V K + + N LE + ++ + +V E ++ L P NIH +I+D +ID+ +K L ++E+ + + V + + DV M +++ DE +IF ++HDA+++ L H
Sbjct: 375 QELIAFGVSNMFGASFRSFAASTALSRTAIQESTGGKTQIAGILSAMMVLIVIVGVGFLLEPLPRSVLGALVIVNLKGMLMQFSELPFLWRNDRPDFVTWMVTFMASLFLGLDLGLAVGIGAELFTVVYRTQFPRCSVLANISGTDLYRDRKDYTSIYEPDGVKIFKIPSPIFFANIDFFRDKLVQEVGFNPMRVLKKRNKALRKIRKMLCNGELEVSDRGPVLRQPSVDTSEGSMEDLDQPIDFSDLPIQVNWNSQLPANISVPPVNIHSLILDFCAVSFIDVSALKGLKATLKEFIRIEVDVYIVS--CDVYIM-EKLQHCTFFDDEIKTSIFYPTLHDAMLHILETH 721 HSP 2 Score: 65.855 bits (159), Expect = 5.763e-11 Identity = 37/122 (30.33%), Postives = 68/122 (55.74%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+ L+SGFT +A+ + +QL++ G+ G ++ TL+ V ++ +TN+ V T+I+I+ L + IN K+ PIPIE+++ V S + +++V +VG ++ G
Sbjct: 206 YLSETLVSGFTTAAAVHILVSQLRFVLGLDFPGINGPLAIIYTLVEVFSRITSTNVADLV-TSIAIMALVLIVKEINDRFKSKLPVPIPIEVIMTVIACGVSYAFNFEERFDVVIVGEMVNG 326
BLAST of STAS domain-containing protein vs. Ensembl Zebrafish
Match: slc26a4 (solute carrier family 26 member 4 [Source:ZFIN;Acc:ZDB-GENE-060503-544]) HSP 1 Score: 163.696 bits (413), Expect = 1.870e-43 Identity = 111/347 (31.99%), Postives = 191/347 (55.04%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMV-KLRXXXXXXXXXX--------------------------XNQSLEEME----NTDLIAKRAV-FQEELD---SLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTD-VRRMFYRIETSQLIHDENIFVSVHDAVI 1295
+E IAFG+ NIF F + ++ ++SR+AVQE+ GGK+Q+ L+S ++++ V+L +GP QPL +LA ++I LK M ++ E+ LW + D +W+ + L ++ L + GL+AG+ + ++V+RTQ P+ LG + TD+YKN+ Y EIPG+KIF+ IY+A D+FK+ L ++ +D + V K R + ++K K N+ EME TD K V + EL S+ +IH +++D S+ ++D+V K L V++E+ + +SV +A + VR+M + ++ + +F+SVHDA++
Sbjct: 380 QELIAFGVSNIFGGCFSSFVASTALSRTAVQESTGGKSQVAGLISAVMVMIVILALGPFLQPLQKSVLAGIVIANLKGMFLQISEVPVLWRQNRTDCFIWIASCLASVVLGLDVGLLAGLVFEMGTVVVRTQFPSCATLGNVPNTDIYKNMKDYKKVDEIPGVKIFKCNSPIYFANIDYFKEKLRDEVGFDAVRVFKKRNKALKKIHKLIKKGKLQVTEAGLVPVASLGVENKGFENEPGHEMEKQASKTDSEVKIQVDWTSELPVSVSVPRVHIHSLVVDFSSVSFLDVVAAKSLKLVVKEFIRIGVSVYIAGCDGELVRKMEALSFFDEEVNRDLLFLSVHDAIL 726 HSP 2 Score: 71.633 bits (174), Expect = 7.235e-13 Identity = 43/122 (35.25%), Postives = 65/122 (53.28%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPL+ GFT +A VF +Q+K V + G FS TLI V + N+ + ++I ++ K IN KI PIPIE++V V + S +DL+++Y S+V + +G
Sbjct: 211 YLSDPLVGGFTTAAAFHVFISQIKTILSVPTHNHNGFFSFAYTLIDVGSNINQANMADLIAGLLTISIVMAVKE-INTKFQHKIPVPIPIEVIVTVIASAISHVMDLNSQYGASIVHNLPRG 331
BLAST of STAS domain-containing protein vs. Ensembl Xenopus
Match: slc26a6 (solute carrier family 26 member 6 [Source:NCBI gene;Acc:780378]) HSP 1 Score: 146.747 bits (369), Expect = 3.763e-51 Identity = 79/184 (42.93%), Postives = 120/184 (65.22%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSL 914
+E IA GL N SFF C+ ++SRS VQE+ GG +Q+ S VS ++IL ++L G LFQ LP ILA+V++V LK + +F ++ LW + D VW+VTFL TI L++ GL VA S+++++ RTQ P+ ILG++ TD+Y++VA + EI GIKIFR ++Y+A + + +S+
Sbjct: 341 QELIALGLSNSIGSFFQCFTIGTAMSRSLVQESTGGHSQVASAVSSLVILIIILRAGELFQTLPKAILAAVVVVNLKGIYKQFTDVPMLWRSNKIDLLVWVVTFLATILLNLDIGLAVSVAFSLLTVIFRTQKPHYSILGKVDNTDIYRDVAQFDQVTEIQGIKIFRSSCTLYFANANLYAESV 524 HSP 2 Score: 75.8702 bits (185), Expect = 3.763e-51 Identity = 46/123 (37.40%), Postives = 70/123 (56.91%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQGN 369
YLS+PLI G+T +AI V +Q+K GV I++ S+ ++ +C +LP TNI + ++ I+I +L V K +N KI PIPIEL+ ++ T S +L+ Y V +VG I G
Sbjct: 206 YLSEPLIRGYTSAAAIHVTVSQMKSVLGVQISQRSHPLSLIYAIVNLCAKLPETNIASLLIGGIAITVLFVVK-FLNDKYSSKIRMPIPIELITLIVATGISYGANLNQVYGVDIVGEIPTGK 327
BLAST of STAS domain-containing protein vs. Ensembl Xenopus
Match: SLC26A5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:100497573]) HSP 1 Score: 181.415 bits (459), Expect = 7.597e-50 Identity = 114/328 (34.76%), Postives = 185/328 (56.40%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQ-------------EELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENI-FVSVHDAVIN 1298
+E IA G+ N SFF + S+SRS VQE+ GG TQI L+S +++L V++ IG LFQPLP +LA++++V LK M +F ++ LW S + S+W+V+FL ++ L + YGL+ V +I++++ RTQSP ILGQ+ TD+Y +V Y + E IKIF+ S+Y+A + + +L K DP + + K K + EM+ + K+AV + +EL+ + P ++H II+D + ++D VGVK L +I+EYK + ++VL++ V + + + +I F S+HDAVI+
Sbjct: 331 QELIALGVCNSVGSFFQTFSVTCSMSRSLVQESTGGNTQIAGLLSSLMVLLVIVVIGYLFQPLPQTVLAAIVMVNLKGMFKQFADIPHLWRTSRLELSIWVVSFLASVSLGLDYGLLVAVTFAILTVIYRTQSPQYRILGQVPNTDIYCDVEQYEEVKEFTDIKIFQANTSLYFANSELYVSALRKKTGIDPAAILI------AKKKAQKRHAREMKKANKTEKKAVLKLVSDYVNLHNTPSDELEYFMTPIISVHWIILDFTPVNFVDSVGVKTLKSIIKEYKEIGVTVLVSGCSGLVVKDLTSLNFFDPSNKRDILFHSIHDAVIH 652 HSP 2 Score: 70.8626 bits (172), Expect = 1.792e-12 Identity = 46/122 (37.70%), Postives = 69/122 (56.56%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++QLKY GV ++ +V + AV + N+ T +L I+LL K IN KK+ PIP+E++VV+ T S L+L + V+VVG I G
Sbjct: 162 YLTEPLVRGFTTAAAVHVFTSQLKYLLGVKTKRFREPLAVIFSFAAVLSNIMTVNVATLILGLSCILLLLGAKE-INDRFKKKLPVPIPMEIIVVIVSTGVSAGLNLEESHAVAVVGKIPTG 282
BLAST of STAS domain-containing protein vs. Ensembl Xenopus
Match: smyd4 (SET and MYND domain containing 4 [Source:Xenbase;Acc:XB-GENE-945037]) HSP 1 Score: 174.481 bits (441), Expect = 3.410e-47 Identity = 104/315 (33.02%), Postives = 184/315 (58.41%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLY 1307
+E A G NI +FF+C+ ++ +++++ V+E+ G KTQ++ +++ +++L VLL I PLF L C+L + IV L+ L KF++L ++W + D ++W+VT + + + GL+ G+A S+ +++R+Q P S +LGQ+ T++Y+++ Y + + GIKIF +E IYY K HFK +LY DP+ V +K KKI+K+N+ ME + +++E+ P +H +IIDC +ID G+ L +V+++Y ++ I +LLA V+ + + + +F SVH AV +LY
Sbjct: 392 QEMYAIGFCNIIPAFFHCFTTSAALAKTLVKESTGCKTQVSGIMTSLVLLLVLLVIAPLFFSLQKCVLGVITIVNLRGALRKFLDLPKMWKVNKVDTTIWLVTMFSSALISTELGLLIGIAFSMFCVIVRSQKPVSTLLGQVDNTEVYESMNAYKNLNIPQGIKIFHFEAPIYYVNKQHFKMTLYKYSGVDPVSVATAKRKKAKKIEKLNRQDGSME---IKTTECLYKEQ-----QP-VHTLIIDCGAIQFIDTAGMNTLKEVLKDYSDIGIQLLLAQCNVTVKNSLRNGDFFKREENTVMFHSVHQAVQFALY 697 HSP 2 Score: 80.8777 bits (198), Expect = 1.216e-15 Identity = 49/124 (39.52%), Postives = 73/124 (58.87%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQGNL 372
YLSD L+SGF G++ + ++Q+KY G++I + GI S+ T I + + + TNI V T+I +L+ + +N K+ PIPIELLVVVA T++S + L Y S+ GTI G L
Sbjct: 223 YLSDSLLSGFATGASFTILTSQVKYLLGISIPRANGIGSLIYTWIYIFQNIHLTNICDLV-TSILCLLVLIPAKELNECYKSKLKAPIPIELLVVVAATLASHFGHLKENYGSSIAGTIPTGFL 345
BLAST of STAS domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000026575.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:34621613:34626696:1 gene:ENSXETG00000013549.1 transcript:ENSXETT00000026575.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 174.096 bits (440), Expect = 4.684e-47 Identity = 108/317 (34.07%), Postives = 178/317 (56.15%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEE--MENTDLIAKRAVFQEELD-SLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMF----YRIETSQLIHDENIFVSVHDAV 1292
+E IA G N +SFF + S ++++S ++E+ G TQ ++S ++L VLL I PLF L NC+L + I +L+ L KF + ++W S D VW V+ L + + + GL+ V SI+ ++ RTQ P + +L +++GT++Y++ Y + IP +KI+R++ S+YYA KD+FK +LY+K +P +V +K +K+ + + + ++I ++ S+ +IH +IIDC +ID VG+ +L +V +Y+ + I V LAN VR M Y S I D +IF SVHDAV
Sbjct: 352 QEMIAIGTCNFITSFFSGFVSCAALTKSLLRESTGANTQFNGIISSSVLLLVLLAIAPLFYSLQNCVLGVITITSLRGALRKFADTPKMWRISKIDTVVWWVSMLASSLITTEIGLLVAVCFSILCVIFRTQRPRATLLAKVTGTEIYEDQFTYKELSNIPNVKIYRFDASLYYANKDYFKTTLYSKTDINPSLVSALQKKAKKEEEAAAIETKNRFIARFNIIKTSGKIRQSASVSVPQFDIHSLIIDCGAMQFIDTVGLGVLKEVKNDYEEIGIRVFLANCNPSVRSMLSNGGYMNNASSGI-DLHIFHSVHDAV 667 HSP 2 Score: 94.7449 bits (234), Expect = 3.710e-20 Identity = 50/122 (40.98%), Postives = 72/122 (59.02%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+PL+SGF GS++ + ++Q+KY FG+ + YG S+ T I V L NTNI V + I+I ++ K IN K+ P P+EL+V++ T+ S Y D HN Y S+ GTI G
Sbjct: 183 YLSEPLLSGFVTGSSLTILTSQMKYLFGLKLTSRYGAGSLVLTWIDVFSNLKNTNICDLVTSIIAIAVIVPVKE-INDRFKSKMKIPCPVELIVIIVATLVSHYFDFHNNYKASICGTIPTG 303
BLAST of STAS domain-containing protein vs. Ensembl Xenopus
Match: SLC26A5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:100497573]) HSP 1 Score: 171.4 bits (433), Expect = 5.380e-46 Identity = 114/355 (32.11%), Postives = 185/355 (52.11%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQ----------------------------------------EELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENI-FVSVHDAVIN 1298
+E IA G+ N SFF + S+SRS VQE+ GG TQI L+S +++L V++ IG LFQPLP +LA++++V LK M +F ++ LW S + S+W+V+FL ++ L + YGL+ V +I++++ RTQSP ILGQ+ TD+Y +V Y + E IKIF+ S+Y+A + + +L K DP + + K K + EM+ + K+AV + +EL+ + P ++H II+D + ++D VGVK L +I+EYK + ++VL++ V + + + +I F S+HDAVI+
Sbjct: 380 QELIALGVCNSVGSFFQTFSVTCSMSRSLVQESTGGNTQIAGLLSSLMVLLVIVVIGYLFQPLPQTVLAAIVMVNLKGMFKQFADIPHLWRTSRLELSIWVVSFLASVSLGLDYGLLVAVTFAILTVIYRTQSPQYRILGQVPNTDIYCDVEQYEEVKEFTDIKIFQANTSLYFANSELYVSALRKKTGIDPAAILI------AKKKAQKRHAREMKKANKTEKKAVLKLTNDVEMAVKHELMNDDSIIDMAANGRNGLSERNLHNTPSDELEYFMTPIISVHWIILDFTPVNFVDSVGVKTLKSIIKEYKEIGVTVLVSGCSGLVVKDLTSLNFFDPSNKRDILFHSIHDAVIH 728 HSP 2 Score: 70.8626 bits (172), Expect = 1.955e-12 Identity = 46/122 (37.70%), Postives = 69/122 (56.56%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++QLKY GV ++ +V + AV + N+ T +L I+LL K IN KK+ PIP+E++VV+ T S L+L + V+VVG I G
Sbjct: 211 YLTEPLVRGFTTAAAVHVFTSQLKYLLGVKTKRFREPLAVIFSFAAVLSNIMTVNVATLILGLSCILLLLGAKE-INDRFKKKLPVPIPMEIIVVIVSTGVSAGLNLEESHAVAVVGKIPTG 331
BLAST of STAS domain-containing protein vs. Ensembl Mouse
Match: Slc26a5 (solute carrier family 26, member 5 [Source:MGI Symbol;Acc:MGI:1933154]) HSP 1 Score: 182.185 bits (461), Expect = 4.780e-50 Identity = 118/343 (34.40%), Postives = 184/343 (53.64%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL-------------------EEMENTDL----IAKRAVFQEELDSLL--NPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYR---IETSQLIHDENIFVSVHDAVINS 1301
+E IA G+ N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LGQ+ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E E+ ++ I + F EEL L N+H +I+D + ++D VGVK L +++EY +V I V LA V R E L E +F S+HDAV+ S
Sbjct: 336 QELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPALIMGARRKAMRKYAKEVGNANVANATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGENVHTVILDFTQVNFVDSVGVKTLAGIVKEYGDVGIYVYLAGCSPQVVNDLTRNNFFENPAL--KELLFHSIHDAVLGS 676 HSP 2 Score: 85.5001 bits (210), Expect = 2.780e-17 Identity = 49/122 (40.16%), Postives = 71/122 (58.20%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +LH Y+V VVGT+ G
Sbjct: 167 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLG 287
BLAST of STAS domain-containing protein vs. Ensembl Mouse
Match: Slc26a5 (solute carrier family 26, member 5 [Source:MGI Symbol;Acc:MGI:1933154]) HSP 1 Score: 182.185 bits (461), Expect = 6.746e-50 Identity = 118/343 (34.40%), Postives = 184/343 (53.64%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL-------------------EEMENTDL----IAKRAVFQEELDSLL--NPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYR---IETSQLIHDENIFVSVHDAVINS 1301
+E IA G+ N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LGQ+ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E E+ ++ I + F EEL L N+H +I+D + ++D VGVK L +++EY +V I V LA V R E L E +F S+HDAV+ S
Sbjct: 373 QELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPALIMGARRKAMRKYAKEVGNANVANATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGENVHTVILDFTQVNFVDSVGVKTLAGIVKEYGDVGIYVYLAGCSPQVVNDLTRNNFFENPAL--KELLFHSIHDAVLGS 713 HSP 2 Score: 85.5001 bits (210), Expect = 2.959e-17 Identity = 49/122 (40.16%), Postives = 71/122 (58.20%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +LH Y+V VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. Ensembl Mouse
Match: Slc26a2 (solute carrier family 26 (sulfate transporter), member 2 [Source:MGI Symbol;Acc:MGI:892977]) HSP 1 Score: 162.925 bits (411), Expect = 2.868e-44 Identity = 103/310 (33.23%), Postives = 172/310 (55.48%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAV 1292
+E A G NI SFF+C ++ +++++ V+E+ G +TQ++++V+ +++L VLL I PLF L C+L + IV L+ L+KF +L ++W S D +W VT L + L + GL+ GV S+ ++LRTQ P + +LG ++ +++++ Y + GIK+FR+ +YY K+ FK +LY K + +P++VK +K K+ + EEM Q D L +H I+IDCS ++D G+ L +V +Y+ V I VLLA VR R E + + +F S+ +AV
Sbjct: 181 QEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTALVLLLVLLVIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQKPKNSLLGLEEESETFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKK-ALNPVLVKAAWKKAAKR-----KLKEEMVTFRGDPDEVSMQLSHDPL---EVHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAVGIQVLLAQCNPSVRDSLARGEYCKKEEETLLFYSLSEAV 481 HSP 2 Score: 86.2705 bits (212), Expect = 1.301e-17 Identity = 44/122 (36.07%), Postives = 75/122 (61.48%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSD L+SGF G++ + ++Q KY G+++ + +G+ SV T I + + + NTNI + + + +++L +K +N K+ PIP+EL+VVVA T++S + L+ YN S+ G I G
Sbjct: 12 YLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSHGVGSVITTWIHIFRNIRNTNICDLITSLLCLLVLVPSKE-LNEHFKDKLKAPIPVELIVVVAATLASHFGKLNGNYNSSIAGHIPTG 132
BLAST of STAS domain-containing protein vs. Ensembl Mouse
Match: Slc26a2 (solute carrier family 26 (sulfate transporter), member 2 [Source:MGI Symbol;Acc:MGI:892977]) HSP 1 Score: 162.925 bits (411), Expect = 4.552e-43 Identity = 102/310 (32.90%), Postives = 169/310 (54.52%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAV 1292
+E A G NI SFF+C ++ +++++ V+E+ G +TQ++++V+ +++L VLL I PLF L C+L + IV L+ L+KF +L ++W S D +W VT L + L + GL+ GV S+ ++LRTQ P + +LG ++ +++++ Y + GIK+FR+ +YY K+ FK +LY K + +P++VK K + EEM Q D L +H I+IDCS ++D G+ L +V +Y+ V I VLLA VR R E + + +F S+ +AV
Sbjct: 416 QEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTALVLLLVLLVIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQKPKNSLLGLEEESETFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKK-ALNPVLVKA-----AWKKAAKRKLKEEMVTFRGDPDEVSMQLSHDPL---EVHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAVGIQVLLAQCNPSVRDSLARGEYCKKEEETLLFYSLSEAV 716 HSP 2 Score: 86.2705 bits (212), Expect = 1.725e-17 Identity = 44/122 (36.07%), Postives = 75/122 (61.48%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSD L+SGF G++ + ++Q KY G+++ + +G+ SV T I + + + NTNI + + + +++L +K +N K+ PIP+EL+VVVA T++S + L+ YN S+ G I G
Sbjct: 247 YLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSHGVGSVITTWIHIFRNIRNTNICDLITSLLCLLVLVPSKE-LNEHFKDKLKAPIPVELIVVVAATLASHFGKLNGNYNSSIAGHIPTG 367
BLAST of STAS domain-containing protein vs. Ensembl Mouse
Match: Slc26a3 (solute carrier family 26, member 3 [Source:MGI Symbol;Acc:MGI:107181]) HSP 1 Score: 159.073 bits (401), Expect = 9.123e-42 Identity = 107/349 (30.66%), Postives = 180/349 (51.58%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPI-MVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQ-----------EELDSLLN--------------------PNI--HHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIE-TSQLIHDENIFVSVHDAVINSL 1304
+E IA G+ NIF+ F + + ++SRS VQE+ GGKTQ+ L+S +++L V++ IG L QPL +LA++ + LK MLM+F E+ LW +D +W++TF+F I L + GL A VA +++IV RTQ P L + +++YKN Y + +E G+KIFR IY+A FK+ L + + P+ +++ R + ++K K + L +M I F+ EELD +N P I H +I+D S ++D+ ++ L +++E+ + + V + D R E + D F+++HDA+++ L
Sbjct: 366 QELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDKYDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSNIYKNKKNYAEVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNKALKKIRKLQKRGLIQMTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFDIDWNGDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHIL 714 HSP 2 Score: 67.3958 bits (163), Expect = 1.777e-11 Identity = 45/122 (36.89%), Postives = 69/122 (56.56%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+ LISGFT +AI V +QLK+ + + Y FS++ L +V Q+ TNI V + I ++++ V K IN K+ PIPIEL++ V T S + +++ V+VVG + G
Sbjct: 197 YLSESLISGFTTAAAIHVLVSQLKFMLQLPVPAYSDPFSIFKVLESVFTQIQKTNIADLVTSVIILVVVFVFKE-INQRYRSKLPVPIPIELIMTVIATGVSYGCNFEDRFGVAVVGNMSLG 317
BLAST of STAS domain-containing protein vs. UniProt/SwissProt
Match: sp|P58743|S26A5_HUMAN (Prestin OS=Homo sapiens OX=9606 GN=SLC26A5 PE=1 SV=1) HSP 1 Score: 183.726 bits (465), Expect = 1.238e-49 Identity = 119/345 (34.49%), Postives = 187/345 (54.20%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL---------EEMENTDL--------------IAKRAVFQEELDSLLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV-----RRMFYRIETSQLIHDENIFVSVHDAVINS 1301
+E IA GL N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LG++ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E++ D I ++ F EE+ + P N+H +I+D + +ID VGVK L +++EY +V I V LA V R F+ E L E +F S+HDAV+ S
Sbjct: 373 QELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF--ENPALW--ELLFHSIHDAVLGS 713 HSP 2 Score: 84.3445 bits (207), Expect = 6.082e-16 Identity = 49/122 (40.16%), Postives = 70/122 (57.38%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +L YNV VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q99NH7|S26A5_MOUSE (Prestin OS=Mus musculus OX=10090 GN=Slc26a5 PE=2 SV=3) HSP 1 Score: 182.185 bits (461), Expect = 4.719e-49 Identity = 118/343 (34.40%), Postives = 184/343 (53.64%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL-------------------EEMENTDL----IAKRAVFQEELDSLL--NPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYR---IETSQLIHDENIFVSVHDAVINS 1301
+E IA G+ N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LGQ+ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E E+ ++ I + F EEL L N+H +I+D + ++D VGVK L +++EY +V I V LA V R E L E +F S+HDAV+ S
Sbjct: 373 QELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPALIMGARRKAMRKYAKEVGNANVANATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGENVHTVILDFTQVNFVDSVGVKTLAGIVKEYGDVGIYVYLAGCSPQVVNDLTRNNFFENPAL--KELLFHSIHDAVLGS 713 HSP 2 Score: 85.5001 bits (210), Expect = 2.070e-16 Identity = 49/122 (40.16%), Postives = 71/122 (58.20%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +LH Y+V VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9JKQ2|S26A5_MERUN (Prestin OS=Meriones unguiculatus OX=10047 GN=SLC26A5 PE=1 SV=1) HSP 1 Score: 181.8 bits (460), Expect = 6.607e-49 Identity = 120/345 (34.78%), Postives = 186/345 (53.91%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL-------------------EEMENTDL----IAKRAVFQEELDSLL--NPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV-----RRMFYRIETSQLIHDENIFVSVHDAVINS 1301
+E IA G+ N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LGQ+ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E E+ ++ I + F EEL + N+H II+D + +ID VGVK L +++EY +V I V LA V R F+ E L E +F S+HDAV+ S
Sbjct: 373 QELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPALIMGARRKAMRKYAKEVGNANIANAAVVKVDGEVDGENATKPEEEDDEVKYPPIVIKTTFPEELQRFMPQTENVHTIILDFTQVNFIDSVGVKTLAVMVKEYGDVGIYVYLAGCSPQVVNDLTRNRFF--ENPAL--KELLFHSIHDAVLGS 713 HSP 2 Score: 85.5001 bits (210), Expect = 2.474e-16 Identity = 49/122 (40.16%), Postives = 71/122 (58.20%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +LH Y+V VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9EPH0|S26A5_RAT (Prestin OS=Rattus norvegicus OX=10116 GN=Slc26a5 PE=1 SV=1) HSP 1 Score: 181.03 bits (458), Expect = 1.173e-48 Identity = 118/346 (34.10%), Postives = 184/346 (53.18%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLRXXXXXXXXXXXNQSL-------------------EEMENTDL----IAKRAVFQEELDSLL--NPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV------RRMFYRIETSQLIHDENIFVSVHDAVINS 1301
+E IA G+ N S F + + S+SRS VQE GGKTQ+ ++ ++IL V+L G LF+ LP +L++++IV LK M M+F +L W S + ++W+ TF+ ++FL + YGLI V +++++++ RTQSP+ +LGQ+ TD+Y ++ Y + EIPGIKIF+ IYYA D + +L K +P IM R + + N ++ E E+ ++ I + F EEL L NIH +I+D + ++D VGVK L +++EY +V I V LA V R F +L +F S+HDAV+ S
Sbjct: 373 QELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYTVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPAIIMGARRKAMRKYAKEVGNANIANATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGENIHTVILDFTQVNFMDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTSNRFFENPALKEL-----LFHSIHDAVLGS 713 HSP 2 Score: 85.5001 bits (210), Expect = 2.263e-16 Identity = 49/122 (40.16%), Postives = 71/122 (58.20%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +A+ VF++ LKY FGV +Y GIFSV + +AV + + N N+ + + + LL K N +K+ PIP+E VV GT S +LH Y+V VVGT+ G
Sbjct: 204 YLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE-FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLG 324
BLAST of STAS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8CIW6|S26A6_MOUSE (Solute carrier family 26 member 6 OS=Mus musculus OX=10090 GN=Slc26a6 PE=1 SV=2) HSP 1 Score: 171.785 bits (434), Expect = 2.555e-45 Identity = 113/371 (30.46%), Postives = 192/371 (51.75%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTK--ISYDPIMVKLR------------------------XXXXXXXXXXXNQSLEEMENTDLIAKRA-VFQ-EELDSLLN---------------------PNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQL----IHDENIFVSVHDAVINSLYDHK 1316
+E +A GL N+ FF C+P + S+SRS VQE+ GG TQ+ VS + IL +++ +G LF+ LP +LA+VIIV LK M+ +F ++ LW + D +W+VTF+ TI L++ GL + S++ +V+R Q P+ +LGQ+ TD+Y++VA Y E+PG+K+FR ++Y+A + + SL K + D ++ + + KI +N +LE++++ D+ A V Q EEL +++ P H +I+D ST ++D V +K L + +++ + + V +A + V ++E I +++F SVHDAV +L K
Sbjct: 379 QELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQVAGAVSSLFILLIIVKLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVVVRMQLPHYSVLGQVPDTDIYRDVAEYSGAKEVPGVKVFRSSATLYFANAELYSDSLKEKCGVDVDRLITQKKKRIKKQEMKLKRMKKAKKSQKQDASSKISSVSVNVNTNLEDVKSNDVEGSEAKVHQGEELQDVVSSNQEDAKAPTMTSLKSLGLPQPGFHSLILDLSTLSFVDTVCIKSLKNIFRDFREIEVEVYIAACYSPV---VAQLEAGHFFDESITKQHVFASVHDAVTFALSHRK 746 HSP 2 Score: 83.9593 bits (206), Expect = 7.035e-16 Identity = 46/122 (37.70%), Postives = 74/122 (60.66%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+PL+ +T +++ V +QLKY FG+ ++ + G SV T++ VC QLP T +P V+TAI + V ++N L +++ PIP ELL ++ T S + L++++ V VVG I G
Sbjct: 210 YLSEPLVRSYTTAASVQVLVSQLKYVFGIKLSSHSGPLSVIYTVLEVCAQLPET-VPGTVVTAIVAGVALVLVKLLNEKLHRRLPLPIPGELLTLIGATGISYGVKLNDRFKVDVVGNITTG 330
BLAST of STAS domain-containing protein vs. TrEMBL
Match: A0A0H3YFH1 (Slc26a-8 OS=Schmidtea mediterranea OX=79327 GN=slc26a-8 PE=2 SV=1) HSP 1 Score: 393.66 bits (1010), Expect = 2.321e-126 Identity = 209/332 (62.95%), Postives = 259/332 (78.01%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGD-----------CHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDHKIQ 1322
+E IA+G+MN +SFF CYPSA S+SRSAVQE+ GGKTQ+TSLVS L+LFVLLFIGP+F LPNCIL+++IIVALK M M+F ELKELWLFSIWDFS W+V FL T F+DV+YGL+ G+ SI+ I+LRTQ+P SHILGQI GTDLYKNV VY + C EI GIKIFRYEGS+YYAC D+FK SLY KISY+P ++KLRI K+++K+KK+ Q EN+ ++ + EL+ L +P IHH+IIDCSTWGYID VGVK L+QVIEEYK++NI+VLLANPKTDVR +R + S +I D IFVSVHDAVINS+Y+ K++
Sbjct: 411 NQELIAYGIMNFVASFFLCYPSASSLSRSAVQESVGGKTQLTSLVSSFLLLFVLLFIGPVFHTLPNCILSAIIIVALKGMFMQFAELKELWLFSIWDFSTWVVAFLGTAFIDVEYGLMIGIGFSILMIMLRTQNPKSHILGQIKGTDLYKNVEVYNEFMESNCNCHFTCEEIDGIKIFRYEGSLYYACSDNFKSSLYNKISYNPRLIKLRILKLERKLKKLKQHNNNFENSPFFEEKTQLETELEKLKHPIIHHLIIDCSTWGYIDYVGVKTLNQVIEEYKSINITVLLANPKTDVRATIFRNDASSIIDDRIIFVSVHDAVINSVYERKME 742 HSP 2 Score: 125.176 bits (313), Expect = 6.659e-27 Identity = 69/122 (56.56%), Postives = 92/122 (75.41%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFTVG+++ VF++Q+KYCFG+ I K +G+F++ T + K LP TNIPT VLT + II+L VTK INP ++KKI PIP+EL+VV+ GTV S+YL L+ + V +VG I QG
Sbjct: 242 YLSDPLISGFTVGASMHVFTSQIKYCFGLNIPKQFGVFNIAKTYFYIAKNLPKTNIPTLVLTVVVIIVLFVTKEWINPRVVKKIRVPIPMELIVVIIGTVVSKYLLLNENHKVRIVGEISQG 363
BLAST of STAS domain-containing protein vs. TrEMBL
Match: A0A0H3YKD1 (Slc26a-4 OS=Schmidtea mediterranea OX=79327 GN=slc26a-4 PE=2 SV=1) HSP 1 Score: 345.125 bits (884), Expect = 1.946e-110 Identity = 182/183 (99.45%), Postives = 183/183 (100.00%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKK 908
T+EFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITSLVSVILILFVLLFIGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKK
Sbjct: 303 TQEFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITSLVSVILILFVLLFIGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKK 485 HSP 2 Score: 242.276 bits (617), Expect = 1.020e-70 Identity = 122/122 (100.00%), Postives = 122/122 (100.00%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG
Sbjct: 134 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 255
BLAST of STAS domain-containing protein vs. TrEMBL
Match: A0A0H3YFG7 (Slc26a-3 OS=Schmidtea mediterranea OX=79327 GN=slc26a-3 PE=2 SV=1) HSP 1 Score: 317.39 bits (812), Expect = 9.182e-100 Identity = 165/320 (51.56%), Postives = 242/320 (75.62%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLE-EMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDHKI 1319
+EF+A+G+MN+F+SFF C+PSA S+SRSAVQE+ GGK+Q++SL+S IL++FVLLFIG F+ LPNCILAS+IIVALK + MK ELK+LW FS+ DFS+W++TFL T+ LDV+YGL+ G LSI S+VL+TQ+P S+ILGQI TD+Y N+++Y +C EI GIKIF+YEGS+YYA ++FKK+LY KI +PI + + + ++ K+ I + E E + D + K++ +EELD L IIIDCS + +ID +G+K ++QVIEEY+ +NISV L + K D+R+ F++ + I+D+ +++S+HDAV++ L ++
Sbjct: 182 QEFLAYGMMNVFASFFSCFPSAASLSRSAVQESVGGKSQLSSLISSILLVFVLLFIGQFFENLPNCILASIIIVALKGLFMKCAELKDLWRFSLMDFSIWLITFLGTVILDVEYGLLVGTMLSIFSVVLKTQNPKSYILGQIDKTDIYCNISLYSECKEILGIKIFQYEGSVYYASCENFKKNLYQKIGLNPIEIFFKKRSLENKLATIQKKFEKENQMPDFMEKKSTIEEELDQLNKSTEFSIIIDCSNFQFIDAMGMKTINQVIEEYQIINISVFLTSLKYDIRKKFHQFNSPCHINDKMVYLSIHDAVVSILRQRRV 501 HSP 2 Score: 133.65 bits (335), Expect = 2.131e-30 Identity = 64/122 (52.46%), Postives = 85/122 (69.67%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDP+ISGFTVGS++ VF++Q+KYCFGV I +YGIF+V NT+ V K + TNIPT + I I LL TK INP +M + P+P+EL VVV G ++S+Y LH + V +VG I +G
Sbjct: 12 YLSDPIISGFTVGSSVHVFTSQIKYCFGVEIQTFYGIFNVINTITEVIKNISETNIPTMSMAIICISLLIFTKEAINPYVMLRFRIPVPMELFVVVGGILASEYFSLHKNHKVLIVGEISKG 133
BLAST of STAS domain-containing protein vs. TrEMBL
Match: A0A1I8HM76 (STAS domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 261.536 bits (667), Expect = 9.458e-77 Identity = 145/335 (43.28%), Postives = 215/335 (64.18%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLR---------XXXXXXXXXXXNQSLEEM-ENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDHKIQIE 1328
++E IA+G+ N +FF+C+P+ S+SRSAVQ++ GGKTQ+ +LVS L+L VLLF+G F+ +PNC L+++I+VA+K ML + E LW S +DF W+VT L + L V YGLI G+A S+ SI++RTQSP S ILG+I+GTDLYKNV Y D E+ G+KIFR+EGS+Y+AC ++F++SLY K +P I+ + R + ++ M E+ A +AV LD P + H+I+D STWGYID VGV+ L Q I+EY+++ ++V +ANPK +R R + + + I+VSVHDAV+ + +D + +
Sbjct: 297 SQELIAYGICNTVGAFFHCWPAGSSLSRSAVQDSMGGKTQVAALVSSTLLLLVLLFVGKYFETVPNCCLSAIILVAIKGMLEQVKEAPILWRLSPYDFWTWIVTCLGVVLLSVDYGLIMGLAFSVFSIIVRTQSPTSSILGRITGTDLYKNVHAYDDIEEVAGLKIFRFEGSLYFACAENFRESLYRKTGVNPRRIVQQRRRLGEKYARVTATSDASTATVKRTFTRMSESEKAEAAKAV---GLDWPRVP-VQHVILDASTWGYIDYVGVRALSQAIQEYRDIGVAVYIANPKCGIRACLERSDFYEKNRYDIIYVSVHDAVLAAQFDQRAALR 627 HSP 2 Score: 100.908 bits (250), Expect = 5.531e-19 Identity = 54/122 (44.26%), Postives = 77/122 (63.11%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFT+G A+ VFS+Q+KY G+++ G+ S+ + + TN T + A+++++L VTK +NP + KKI P+P EL++V GTV S DL YNV +VGTI G
Sbjct: 127 YLSDPLISGFTMGVAVHVFSSQIKYVLGISVPGRNGLASLPLHYYDLACNIGQTNFVTLGIAAVAVVILYVTKEFVNPRVRKKIKAPLPTELIIVTLGTVISYAFDLKKNYNVKIVGTIPTG 248
BLAST of STAS domain-containing protein vs. TrEMBL
Match: A0A1I8HTX0 (STAS domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 261.922 bits (668), Expect = 4.017e-75 Identity = 145/335 (43.28%), Postives = 215/335 (64.18%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP--IMVKLR---------XXXXXXXXXXXNQSLEEM-ENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDHKIQIE 1328
++E IA+G+ N +FF+C+P+ S+SRSAVQ++ GGKTQ+ +LVS L+L VLLF+G F+ +PNC L+++I+VA+K ML + E LW S +DF W+VT L + L V YGLI G+A S+ SI++RTQSP S ILG+I+GTDLYKNV Y D E+ G+KIFR+EGS+Y+AC ++F++SLY K +P I+ + R + ++ M E+ A +AV LD P + H+I+D STWGYID VGV+ L Q I+EY+++ ++V +ANPK +R R + + + I+VSVHDAV+ + +D + +
Sbjct: 514 SQELIAYGICNTVGAFFHCWPAGSSLSRSAVQDSMGGKTQVAALVSSTLLLLVLLFVGKYFETVPNCCLSAIILVAIKGMLEQVKEAPILWRLSPYDFWTWIVTCLGVVLLSVDYGLIMGLAFSVFSIIVRTQSPTSSILGRITGTDLYKNVHAYDDIEEVAGLKIFRFEGSLYFACAENFRESLYRKTGVNPRRIVQQRRRLGEKYARVTATSDASTATVKRTFTRMSESEKAEAAKAV---GLDWPRVP-VQHVILDASTWGYIDYVGVRALSQAIQEYRDIGVAVYIANPKCGIRACLERSDFYEKNRYDIIYVSVHDAVLAAQFDQRAALR 844 HSP 2 Score: 101.679 bits (252), Expect = 4.347e-19 Identity = 54/122 (44.26%), Postives = 77/122 (63.11%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFT+G A+ VFS+Q+KY G+++ G+ S+ + + TN T + A+++++L VTK +NP + KKI P+P EL++V GTV S DL YNV +VGTI G
Sbjct: 344 YLSDPLISGFTMGVAVHVFSSQIKYVLGISVPGRNGLASLPLHYYDLACNIGQTNFVTLGIAAVAVVILYVTKEFVNPRVRKKIKAPLPTELIIVTLGTVISYAFDLKKNYNVKIVGTIPTG 465
BLAST of STAS domain-containing protein vs. Ensembl Cavefish
Match: slc26a10 (solute carrier family 26 member 10 [Source:NCBI gene;Acc:103043095]) HSP 1 Score: 186.808 bits (473), Expect = 6.601e-52 Identity = 102/315 (32.38%), Postives = 183/315 (58.10%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEME----NTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVI 1295
+E +A G+ N SS F C+PS+ +++ + + E+AGG TQ++ L + +++L VLL IGPLF LP +LA + + +L+ M ++F +L +LW S DF VW+VT+L + L+V GL GV S+++++ RTQ +LG+ S T++Y+ + + C+EIPG+KI Y G IYY + FK + + P ++ R + + K+ +++ +E NT ++ F+ E+ + +++DCS ++D+ G K+ Q+ E + + + + LAN +V ++ ++ ++IFV+VHDAVI
Sbjct: 361 QELLAHGISNTVSSLFTCFPSSATLATTNILESAGGYTQLSGLFTSLVVLVVLLLIGPLFYFLPKAVLACINVTSLRQMFLQFQDLPDLWRVSRIDFMVWLVTWLSVVVLNVDLGLAIGVVFSMMTVICRTQRAGCSVLGRASNTEIYRPINNHNKCYEIPGVKILTYNGPIYYGNRSFFKADVNQLLGLTPERIRSREKARKALEKREREAINTVERGVANTSFSSENEFFKSEMS---ENEVQAVLMDCSGVVFVDVAGAKLFIQMCIECQKMGVRIYLANCNENVLKILTSSGLMNYMNPQHIFVTVHDAVI 672 HSP 2 Score: 72.7886 bits (177), Expect = 3.222e-13 Identity = 40/122 (32.79%), Postives = 70/122 (57.38%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+P+I FT +A V +QL+ G+ + ++ G FS++ TL +V + LP+TN+ +++ + + +L K V N + + PIP+E+L V+ T + L + Y+V +VG I G
Sbjct: 192 YLSEPIIKAFTSAAAFHVTISQLQSMLGLRLPRHTGTFSLFKTLASVLENLPHTNLAELLISLVCLAVLIPIKEV-NTRFRQHLRTPIPVEILTVIIATGVAYAFSLDSTYDVQIVGHIPAG 312
BLAST of STAS domain-containing protein vs. Ensembl Cavefish
Match: slc26a2 (solute carrier family 26 member 2 [Source:NCBI gene;Acc:103047169]) HSP 1 Score: 181.8 bits (460), Expect = 4.518e-50 Identity = 108/315 (34.29%), Postives = 181/315 (57.46%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV-----RRMFYRIETSQLIHDENIFVSVHDAV 1292
+E A G NIF SFF C+ ++ +++++ V+E+ G +TQ++ L++ +++L VLL I PLF L C+LA +I+V L+ L KF ++ ++W + D ++W+VT + ++ + GL+ GV +S S++ RTQ + LGQ ++++++A Y H PG+ +FRYE IYYA + FKKSLY + DP+ K R + + + + ++LE+ D A +F + P H +IIDCS ++D GV L +V ++YK + + +LLA T V R +Y +T ENIF ++ DAV
Sbjct: 377 QEMYAIGFCNIFPSFFRCFTTSAALTKTLVKESTGCQTQVSGLITALVLLLVLLVIAPLFYSLQKCVLAVIIVVNLRGALRKFRDVPQMWRTNRVDATIWLVTMATSALVNTELGLLVGVLVSAFSVLGRTQRAQAFKLGQAGDYEIFEDLASYKGLHTHPGVAVFRYEAPIYYANQTLFKKSLYRNVGLDPVKEKAR--RKKLEKQNKQKTLEDGVKQDHEASTNMFLSQ-----GPAFHTLIIDCSAVLFLDTAGVGALKEVHKDYKELGVRLLLAQCNTSVIDSLRRAGYYDHKTGS---PENIFHTISDAV 681 HSP 2 Score: 76.6406 bits (187), Expect = 1.674e-14 Identity = 42/122 (34.43%), Postives = 67/122 (54.92%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
+LSD L+SGF G+++ + ++QLKY G+ + + G S+ T I++ L TNI + + I +++L TK +N K+ PIP EL VV+ T++S + KY V G I G
Sbjct: 208 FLSDSLLSGFATGASLTILTSQLKYLLGLKLPRAQGWGSLIKTWISLLTNLGQTNICDLITSLICLLVLIPTKE-LNDRFKSKLKAPIPFELFVVIIATLASHFGQFQEKYGSGVAGAIPTG 328
BLAST of STAS domain-containing protein vs. Ensembl Cavefish
Match: slc26a5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:103036170]) HSP 1 Score: 167.548 bits (423), Expect = 8.333e-45 Identity = 117/354 (33.05%), Postives = 182/354 (51.41%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKR----------AVFQEELDS---------------------------LLNP--NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPK----TDVRRMFYRIETSQLIHDENIFVSVHDAVI 1295
+E IA GL N SSFF + S+SRS VQE+ GGKTQI L+ +L+L V++ IG +F+PLP +LA+VI+V L M + ++ LW S + +VW+V F+ ++ L + +GL+ V +I++++ RTQ P S ILGQI T LY ++ Y + E G+KIF SIY+A D + L K DP + + QK K + + ++++ KR V E LD L P +H II+D + ++D VG+K + VI+EY V++ V+LA +D+R+M + S + + IF ++HDAV+
Sbjct: 382 QEMIALGLCNFASSFFQTFVITSSMSRSLVQESTGGKTQIAGLLGSLLVLLVIVAIGFMFEPLPQTVLAAVIMVNLLGMFKQVRDIPALWRTSKIELAVWLVAFVASVLLGLDFGLLVAVGFAILTVIYRTQRPKSVILGQIPNTGLYYDIDEYEEASECSGVKIFHSNSSIYFANSDQYVNHLKDKTGIDPTRLLAERKSQQKHAKTKKEEKKNLKDSSSPQKRNAVAKLDMELGVAHEVLDESEKQVELHGNGQLPEAQSEICDSEKVLFLQPLCPVHSIILDFTPVNFMDSVGIKAIKAVIKEYAAVDVRVVLAGCNRTLLSDLRKMQF---FSGPVTTDIIFPTIHDAVL 732 HSP 2 Score: 88.1965 bits (217), Expect = 3.184e-18 Identity = 51/122 (41.80%), Postives = 74/122 (60.66%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YL++PL+ GFT +AI VF +QLKY FGV ++ G SV +LIAV K + +TN+ T ++ + I+ L K+V N KK+ PIP E++VV+ T S + L Y V +VG+I G
Sbjct: 213 YLAEPLVRGFTTAAAIHVFVSQLKYLFGVKTKRFSGPLSVLYSLIAVFKDITSTNVTTLIVGLVCIVFLYSVKDV-NERFKKKLPIPIPGEIIVVIVSTGVSYGMALFENYQVDIVGSIPVG 333
BLAST of STAS domain-containing protein vs. Ensembl Cavefish
Match: slc26a1 (sulfate anion transporter 1-like [Source:NCBI gene;Acc:103035611]) HSP 1 Score: 162.925 bits (411), Expect = 2.345e-43 Identity = 102/284 (35.92%), Postives = 175/284 (61.62%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV 1214
+E +A G NI SFF+C+ ++ +++++ V+++ G +TQ++S+VS +++L VLLF+ P F L C+LA +IIV+L+ L KF ++ LW S D +VW+VT + V+ GL+ GV +S+I +V++TQ P + +LGQI T+ Y+++ Y +P IKIFR++ +YYA K+ F KSLY + +P + K R +K++KK K+ +N + + ELD H II+DCS+ +ID G+ ++++YK +++S++LA T+V
Sbjct: 390 QEMLAIGFCNIIPSFFHCFTTSAALAKTMVKDSTGCQTQVSSVVSALVVLLVLLFLAPFFYSLQKCVLACIIIVSLRGALRKFRDVPTLWRLSKIDAAVWIVTMFSAALISVEIGLVIGVVVSMICVVVQTQFPKASLLGQIENTNHYEDMDDYSHLVSVPKIKIFRFQAPLYYANKEFFLKSLYKAVGLEPFLEKTRRKKMEKKAKERAAKKTMGDNDNGDVSIGLIAPELD------FHTIILDCSSMSFIDTTGITTFKGLLKDYKEISVSIILACCNTNV 667 HSP 2 Score: 70.8626 bits (172), Expect = 1.198e-12 Identity = 40/122 (32.79%), Postives = 66/122 (54.10%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS P++ GF G++ + + Q KY G+ I ++ G +V T I + K + TN + +AI I +L K + + ++ P+P EL+VV TV S + DL+ +Y+ S+ G I G
Sbjct: 221 YLSAPMLDGFATGASCTILTVQAKYLLGLKIPRHQGYGTVVVTWINIFKNIHKTNFCDMITSAICIAVLVAGKELQDR-YKNRLKMPLPTELVVVGLATVVSHFADLNGQYSSSISGAIPTG 341
BLAST of STAS domain-containing protein vs. Ensembl Cavefish
Match: slc26a1 (sulfate anion transporter 1-like [Source:NCBI gene;Acc:103035611]) HSP 1 Score: 162.925 bits (411), Expect = 2.345e-43 Identity = 102/284 (35.92%), Postives = 175/284 (61.62%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDV 1214
+E +A G NI SFF+C+ ++ +++++ V+++ G +TQ++S+VS +++L VLLF+ P F L C+LA +IIV+L+ L KF ++ LW S D +VW+VT + V+ GL+ GV +S+I +V++TQ P + +LGQI T+ Y+++ Y +P IKIFR++ +YYA K+ F KSLY + +P + K R +K++KK K+ +N + + ELD H II+DCS+ +ID G+ ++++YK +++S++LA T+V
Sbjct: 390 QEMLAIGFCNIIPSFFHCFTTSAALAKTMVKDSTGCQTQVSSVVSALVVLLVLLFLAPFFYSLQKCVLACIIIVSLRGALRKFRDVPTLWRLSKIDAAVWIVTMFSAALISVEIGLVIGVVVSMICVVVQTQFPKASLLGQIENTNHYEDMDDYSHLVSVPKIKIFRFQAPLYYANKEFFLKSLYKAVGLEPFLEKTRRKKMEKKAKERAAKKTMGDNDNGDVSIGLIAPELD------FHTIILDCSSMSFIDTTGITTFKGLLKDYKEISVSIILACCNTNV 667 HSP 2 Score: 70.8626 bits (172), Expect = 1.198e-12 Identity = 40/122 (32.79%), Postives = 66/122 (54.10%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS P++ GF G++ + + Q KY G+ I ++ G +V T I + K + TN + +AI I +L K + + ++ P+P EL+VV TV S + DL+ +Y+ S+ G I G
Sbjct: 221 YLSAPMLDGFATGASCTILTVQAKYLLGLKIPRHQGYGTVVVTWINIFKNIHKTNFCDMITSAICIAVLVAGKELQDR-YKNRLKMPLPTELVVVGLATVVSHFADLNGQYSSSISGAIPTG 341
BLAST of STAS domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003427.1 (pep scaffold:Pmarinus_7.0:GL476526:256569:262630:-1 gene:ENSPMAG00000003117.1 transcript:ENSPMAT00000003427.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 175.252 bits (443), Expect = 2.606e-48 Identity = 99/313 (31.63%), Postives = 185/313 (59.11%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGT-DLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNP-NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVI 1295
+E IA G NI +FFY + ++ +++++ V+EA G +TQ++++V+ ++L VLL I PLF L C+L + IV L+ KF+++ +W S D S+W VT L + + + GL+ GV +S++ ++RTQ P + + G + T + Y ++ Y + E+PG+++F ++ +YYA K++FK L+ K +P + ++ QK +++ + + L +N +++ K+A+ E + LL + H I+IDCS ++D VGV + ++++Y+++ I V+LA V +R + I D F +HDAV+
Sbjct: 388 QEMIAIGFCNIVPAFFYSFTTSAALAKTLVKEATGCQTQMSAVVTAGVLLLVLLLIAPLFYSLQKCVLGVITIVNLRGAFRKFLDIPRMWQESRVDTSIWFVTMLASALISTEIGLLVGVCVSLLVFIVRTQRPRAALYGCVHDTNNFYADLEAYSNVAEVPGVRVFHFDAPLYYANKEYFKSQLFLKTRVNPAL-EVAAQKKRQEKLQKRKKLSGSDNGEIVNKQAML--EFNKLLPTFDFHTIVIDCSAMQFMDSVGVGAVKSIMKDYQSIGIRVILACCNPTVMDSLHRGKCISTIEDNLTFCLIHDAVL 697 HSP 2 Score: 80.1073 bits (196), Expect = 2.417e-16 Identity = 45/124 (36.29%), Postives = 72/124 (58.06%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQGNL 372
YLS+P++SGF GS++ V ++Q+KY G+ I + G ++ T + Q+ NTN+ V+T+I IL+ V +N ++ P PIEL+VVVA T++S + Y+ S+ G I G L
Sbjct: 219 YLSEPMLSGFVTGSSLTVLTSQMKYLLGIHIPRASGAGALLKTWYHIFSQISNTNVCD-VVTSIICILVLVPAKELNEHFKARLKAPFPIELVVVVAATLASHFGGFKENYSSSIAGHIPTGFL 341
BLAST of STAS domain-containing protein vs. Ensembl Sea Lamprey
Match: si:ch211-117c9.2 (si:ch211-117c9.2 [Source:ZFIN;Acc:ZDB-GENE-110408-11]) HSP 1 Score: 166.392 bits (420), Expect = 6.916e-46 Identity = 110/342 (32.16%), Postives = 182/342 (53.22%), Query Frame = 3
Query: 351 DYYTREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLP---NCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDP-----IMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVF-------------------QEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIE-TSQLIHDENIFVSVHDAV 1292
D +E +A GL NIF S F+ + + ++SRS VQ+A GG+TQ+ LVS +L+L V+L I LF+PLP LA+V++V LK M +F ++ +LW D ++WMVTF ++ L + GL V+ +++S+V+RTQ+P ILG+I TD+Y ++ Y + E+ GI+IF+ S+Y+A D + ++L +K DP + K + + + K+ ++ E ++ L AV + E L +P +++D ++D GVK+L ++ +E+K V + V LA + V R S +F+SV DAV
Sbjct: 195 DSNQQELVAIGLSNIFGSIFHSFTISCAMSRSLVQDATGGQTQVAGLVSALLVLIVILAISSLFRPLPRSGQAALAAVVLVNLKGMFKQFADVPQLWRTCRIDLAMWMVTFWASVLLGLDLGLAVAVSFALLSVVIRTQTPKYSILGKIPNTDIYLDLKEYAEAKEVSGIRIFQTNASLYFANADMYTEALISKTGLDPRSLIAVRKKFLAHQQRLERKRRREAGTEAKSATLNLGEAVTRGGEAVDGAEAGHVVLPLEESEEQGLTSPAYRFLVLDFGAVTFVDTPGVKMLKRIFQEHKEVGVQVCLAGCRAVVVTQLERTGFLSGPSSKAQLFLSVPDAV 536 HSP 2 Score: 87.4261 bits (215), Expect = 8.627e-19 Identity = 46/122 (37.70%), Postives = 74/122 (60.66%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+P++ GFT +I V TQLKY FGV++++Y G + T I C L +TN+ + +L I + LA +K + ++ PIP+EL++VV T++S L+L+ K+ V ++G I G
Sbjct: 29 YLSEPMVRGFTTACSIHVCVTQLKYMFGVSVSRYSGPLASEQTTIEFCSHLGHTNLVSLLLCVICTVGLAGSKE-LGDRYRNRLPAPIPLELILVVLATLASSGLELNEKHAVDIIGDIPTG 149
BLAST of STAS domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003699.1 (pep scaffold:Pmarinus_7.0:GL480994:8326:18126:1 gene:ENSPMAG00000003383.1 transcript:ENSPMAT00000003699.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 86.2705 bits (212), Expect = 1.157e-19 Identity = 50/125 (40.00%), Postives = 75/125 (60.00%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYG---IFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPL+S FT +AI V +Q+K G+ + ++ G IF V+ T++ + ++LPNTNI V + + + +L + IN K+ PIP+ELL++V TV S Y L K+ V+VVG I G
Sbjct: 15 YLSDPLVSAFTNAAAIHVLVSQIKNMLGLQVPRFSGPASIFMVFQTMVDIFQKLPNTNIAELVTSLVCLTVLIPVRE-INQRYKSKLKAPIPVELLLIVLATVISFYARLEEKFGVTVVGNIPAG 138 HSP 2 Score: 54.6842 bits (130), Expect = 6.637e-9 Identity = 21/40 (52.50%), Postives = 30/40 (75.00%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQI 482
+E A G+ N+F SFF C+PSA S+SR+++QE GG TQ+
Sbjct: 187 QELFAHGVCNLFGSFFQCFPSAASISRTSIQEGTGGNTQV 226
BLAST of STAS domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006617.1 (pep scaffold:Pmarinus_7.0:GL482475:5949:18084:-1 gene:ENSPMAG00000005984.1 transcript:ENSPMAT00000006617.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 55.4546 bits (132), Expect = 2.002e-9 Identity = 39/124 (31.45%), Postives = 75/124 (60.48%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYG-IFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPI-LMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+PL+ GF+ +++ V +QLK+ G+ + + + + +T VC+ + N+ T +++ +S+ + + K V++ + ++++ P+P ELL+VV GTV S+ L L ++V VVG I G
Sbjct: 20 YLSEPLVRGFSTAASVTVLVSQLKHLLGLALPRRHDQVLGTLHTARDVCRGVLQVNVVTALVSLLSLCSMLLLKRVVHSVPRLRRV--PVPAELLLVVLGTVLSEQLQLSPDHSVDVVGLIPSG 141
BLAST of STAS domain-containing protein vs. Ensembl Yeast
Match: YPR003C_mRNA (Putative sulfate permease; physically interacts with Hsp82p; green fluorescent protein (GFP)-fusion protein localizes to the ER; YPR003C is not an essential gene [Source:SGD;Acc:S000006207]) HSP 1 Score: 67.0106 bits (162), Expect = 2.364e-12 Identity = 71/306 (23.20%), Postives = 123/306 (40.20%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFS---VWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVY-----------GDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTD--VRRMFYR 1232
RE +A G MNI S F P+ G RS + +G ++ ++ + ++ L + + +PNC+L SVI + L++ V + FS V+ VTF TIF ++ G+ G SII+I+ + IL +++GT + N+ Y EI G I R + + + K+ L +E ++ + R + + DS I ++I D ID ++L ++I YK N+ + L N + VRR ++
Sbjct: 409 RELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVL-SVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRL--------------------------DRIERYGSSKIHPGRKSLRSK-DS-----IKYVIFDLGGMTSIDSSAAQVLEEIITSYKRRNVFIYLVNVSINDKVRRRLFK 681
BLAST of STAS domain-containing protein vs. Ensembl Yeast
Match: SUL2 (High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates [Source:SGD;Acc:S000004082]) HSP 1 Score: 65.855 bits (159), Expect = 5.732e-12 Identity = 42/142 (29.58%), Postives = 73/142 (51.41%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQI 788
+E IA G+ N+ +FF YP+ GS SRSA++ +T ++ L S +L L + F +P L++VII A+ +L + W + DF ++VT L T+F ++ G+ + S ++L+ P LG++
Sbjct: 442 QELIAIGVSNLLGTFFNAYPATGSFSRSALKAKCNVRTPLSGLFSGSCVLLALYCLTGAFFYIPKATLSAVIIHAVSDLLASYQTTWNFWKMNPLDFICFIVTVLITVFASIEDGIYFAMCWSCAMLILKVAFPAGKFLGRV 583
BLAST of STAS domain-containing protein vs. Ensembl Yeast
Match: SUL1 (High affinity sulfate permease of the SulP anion transporter family; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates [Source:SGD;Acc:S000000498]) HSP 1 Score: 59.6918 bits (143), Expect = 5.928e-10 Identity = 38/142 (26.76%), Postives = 71/142 (50.00%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQI 788
+E IA G+ N+ +FF+ YP+ GS SRSA++ +T + + + +L L + F +P L++VII A+ +L + W + D ++VT T+F ++ G+ + S ++L+ P LG++
Sbjct: 426 QELIAIGVTNLIGTFFHSYPATGSFSRSALKAKCNVRTPFSGVFTGGCVLLALYCLTDAFFFIPKATLSAVIIHAVSDLLTSYKTTWTFWKTNPLDCISFIVTVFITVFSSIENGIYFAMCWSCAMLLLKQAFPAGKFLGRV 567
BLAST of STAS domain-containing protein vs. Ensembl Nematostella
Match: EDO49691 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG03]) HSP 1 Score: 135.191 bits (339), Expect = 4.386e-34 Identity = 102/320 (31.87%), Postives = 167/320 (52.19%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLE---EMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDH 1313
+E +A+G+ N+ SFF C+P +++R+ VQE TQ+ S+ + LIL VLLF+ PLF LP ILA+V+I L +L +F L++LW D W VT I L V GL GV +I +++R P ILG I T+LY++ IP +KI R+E S+++A K+ + + + +P+ R + ++E E E+ D KR ++ +N NI +I+D S + +ID VG+ + +I E + + V LA +R+ ++++++FVS+HDAV+ +L H
Sbjct: 394 QELLAYGMCNVGGSFFSCFPICNALARTVVQENLA-STQLCSIPVICLILLVLLFMAPLFYYLPKAILAAVVIANLGGLLKQFARLRQLWCICRTDAVTWFVTCFGVILLGVDLGLGLGVITTIFVVIIRQSRPRVSILGHIKDTELYRDTQECPQAAGIPNVKILRFESSLFFANAGFIKERIMSFM--NPLTPTKRECIPGITTDEAEVTMELNAEKESLD-TTKRTNREQG----VNANIKAVIVDASAFTFIDSVGITAIKTIITEGDSRGVHVCLAACSYHLRKQLEAGGLEPSLNNDHLFVSIHDAVLFTLQAH 705 HSP 2 Score: 81.6481 bits (200), Expect = 1.796e-16 Identity = 48/122 (39.34%), Postives = 72/122 (59.02%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFT GSA++V +QLK+ FG + + G F+ + K + ++N P ++T + +++ VT IN K++ PIP ELLVV GT S L +++ V V+G I +G
Sbjct: 225 YLSDPLISGFTTGSAVLVVLSQLKHIFGQVVPQNTGAFASIKVAAHMLKFIASSN-PGAIITGVLCLVILVTLKFINEKYKKRLPIPIPAELLVVALGTAISYGASLSDEFGVKVLGEIPKG 345
BLAST of STAS domain-containing protein vs. Ensembl Nematostella
Match: EDO48275 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJJ6]) HSP 1 Score: 66.2402 bits (160), Expect = 1.103e-11 Identity = 41/125 (32.80%), Postives = 72/125 (57.60%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSI 734
++E IA GL N+ SSF YP GS SR+AV +G T + + +++ L + P F+ +P LA++II ++ +M ++F + +W D +VTF F F +++YG++AG+ +S+
Sbjct: 348 SQELIALGLANVLSSFVSSYPVTGSFSRTAVNAQSGVATPAGGIFTGAIVILALGVLTPFFKYIPKASLAALIISSVLTM-VEFQIVPRIWRVKKIDLIPLLVTF-FGCFYEIEYGILAGMGVSL 470
BLAST of STAS domain-containing protein vs. Ensembl Medaka
Match: slc26a10 (solute carrier family 26 member 10 [Source:NCBI gene;Acc:101171246]) HSP 1 Score: 189.889 bits (481), Expect = 4.101e-53 Identity = 106/319 (33.23%), Postives = 188/319 (58.93%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLI--AKRAVFQEELDSLLN-------PNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAV 1292
+E +A G+ N S+FF C+PS+ +++ + + E+AGG TQ+ L + +++L VLL IGPLF LP +LA + + +L+ ML++F +L ELW S DF VW+VT+L + L+V GL GV S+++I+ RTQ +LG+ S T++Y+ + + C+E+PG+KI Y G IYY + F++ + + P ++ R +K ++LE+ E+ +I +R + S+ + ++ ++IDCS+ +ID+ G ++ Q+ + +N+ +SV LAN +V ++ ++ ++IFV+VHDAV
Sbjct: 361 QELLAHGISNAVSAFFTCFPSSATLATTNILESAGGHTQLCGLFTSLVVLVVLLLIGPLFYFLPKAVLACINVTSLRQMLLQFQDLPELWRISKLDFMVWIVTWLSVVVLNVDLGLAIGVVFSMMTIICRTQRVACSVLGRASNTEIYRPLENHNKCYEVPGVKILTYNGPIYYGNRSFFREQMSKLLGLTPEKIRRR--------EKAKKALEKQESETVICTVERGIANTSFSSVSDFFKSASESDLEAVLIDCSSVIFIDVAGARLFTQMCTQCQNIGVSVYLANCNENVLKIMTSSGLMSHMNPQHIFVTVHDAV 671 HSP 2 Score: 70.4774 bits (171), Expect = 1.383e-12 Identity = 39/122 (31.97%), Postives = 68/122 (55.74%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+P++ F +A V +QL+ G+ + ++ G FS + TL++V + LP+TN +++ +S+ +L K IN ++ PIP+E+L V+ T L + YN+ +VG I G
Sbjct: 192 YLSEPIVKAFISAAAFHVTISQLQSMLGLRLPRHTGNFSFFKTLVSVMENLPHTNTAELIISLVSLAVLVPVKE-INVRFRHRLRTPIPVEILTVIIATCVVYASSLDSIYNIEIVGDIPAG 312
BLAST of STAS domain-containing protein vs. Ensembl Medaka
Match: slc26a1 (sulfate anion transporter 1 [Source:NCBI gene;Acc:101158870]) HSP 1 Score: 171.4 bits (433), Expect = 2.690e-46 Identity = 107/326 (32.82%), Postives = 182/326 (55.83%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIM-VKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDEN---IFVSVHDAVINSLYDHKIQIE 1328
+E +A GL N+ SFF+ + ++ +++++ V+++ G +TQ++SL+S +++L VLLF P F L C+LA +IIV+L+ L KF E+ W S D VW++T T + V+ GL+ G+ S++ I+ +TQ+P +LG++S TDLY+++ Y P + IFR++ +YYA K+ F KSLY + +P + + R + + K K Q+ +N D+ +ELD H I++DCS +ID G L +++EYK++ +SVLLA V + + E +F +VH AV ++ +H E
Sbjct: 381 QEMVAIGLCNVIPSFFHSFTTSAALAKTMVKDSTGCQTQVSSLISALVVLLVLLFFAPFFHALQKCVLACIIIVSLRGALRKFKEVPAKWRASKNDAIVWLITMFATALISVELGLLVGIIFSMVCIIFKTQNPKFSLLGRVSDTDLYEDLEEYTGLTPPPQVHIFRFQAPLYYANKESFLKSLYKAVGVEPFLELTKRRKAEKAKGKSSKQAKANKKNGDVFI--GPIHKELD------FHTIVLDCSAIPFIDSSGTATLKVLVKEYKDIGVSVLLACCNASVIDALRKAQVFGKNDREMSSLLFYTVHAAVFHAGQEHAEAAE 698 HSP 2 Score: 69.3218 bits (168), Expect = 3.715e-12 Identity = 38/122 (31.15%), Postives = 66/122 (54.10%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS P++ GF G++ + + Q KY G+ I +++G +V T + + TN+ + +AI I +L K I ++ P+P EL+VV T++S + L+++Y+ SV G I G
Sbjct: 212 YLSAPMLDGFATGASFTILTVQAKYLLGLKIPRHHGYGTVPVTWFNIFANIHKTNVCDLITSAICISILVAGKE-IQDRYKNRLKIPLPTELVVVAGATLASHFGKLNSRYSSSVSGHIPTG 332
BLAST of STAS domain-containing protein vs. Ensembl Medaka
Match: slc26a1 (sulfate anion transporter 1 [Source:NCBI gene;Acc:101158870]) HSP 1 Score: 171.4 bits (433), Expect = 2.690e-46 Identity = 107/326 (32.82%), Postives = 182/326 (55.83%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIM-VKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDEN---IFVSVHDAVINSLYDHKIQIE 1328
+E +A GL N+ SFF+ + ++ +++++ V+++ G +TQ++SL+S +++L VLLF P F L C+LA +IIV+L+ L KF E+ W S D VW++T T + V+ GL+ G+ S++ I+ +TQ+P +LG++S TDLY+++ Y P + IFR++ +YYA K+ F KSLY + +P + + R + + K K Q+ +N D+ +ELD H I++DCS +ID G L +++EYK++ +SVLLA V + + E +F +VH AV ++ +H E
Sbjct: 381 QEMVAIGLCNVIPSFFHSFTTSAALAKTMVKDSTGCQTQVSSLISALVVLLVLLFFAPFFHALQKCVLACIIIVSLRGALRKFKEVPAKWRASKNDAIVWLITMFATALISVELGLLVGIIFSMVCIIFKTQNPKFSLLGRVSDTDLYEDLEEYTGLTPPPQVHIFRFQAPLYYANKESFLKSLYKAVGVEPFLELTKRRKAEKAKGKSSKQAKANKKNGDVFI--GPIHKELD------FHTIVLDCSAIPFIDSSGTATLKVLVKEYKDIGVSVLLACCNASVIDALRKAQVFGKNDREMSSLLFYTVHAAVFHAGQEHAEAAE 698 HSP 2 Score: 69.3218 bits (168), Expect = 3.715e-12 Identity = 38/122 (31.15%), Postives = 66/122 (54.10%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS P++ GF G++ + + Q KY G+ I +++G +V T + + TN+ + +AI I +L K I ++ P+P EL+VV T++S + L+++Y+ SV G I G
Sbjct: 212 YLSAPMLDGFATGASFTILTVQAKYLLGLKIPRHHGYGTVPVTWFNIFANIHKTNVCDLITSAICISILVAGKE-IQDRYKNRLKIPLPTELVVVAGATLASHFGKLNSRYSSSVSGHIPTG 332
BLAST of STAS domain-containing protein vs. Ensembl Medaka
Match: si:ch211-117c9.2 (solute carrier family 26 member 6 [Source:NCBI gene;Acc:101162048]) HSP 1 Score: 164.466 bits (415), Expect = 9.284e-44 Identity = 112/359 (31.20%), Postives = 183/359 (50.97%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYD----PIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVF---------------------QEELDSL------LNP--------------NIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSL 1304
+E IA GL N SFF CY S+SRS VQE+ GG TQI +VS +L+L +++ IG LF+ LP +L++++ V LK M +F+++ LW + D VW+VTF+ T+ ++ GL V S+++ + +TQ P+ ILG + TDLY + + EIPGIKIFR +I + + + ++L + D + K R ++ + K++ +SL + +N + A+F E+DS L P H II+D ST G++D V VK+L + ++ +V++ + LA + V + + I +FV+VHDAV++ L
Sbjct: 372 QELIAVGLSNTIGSFFQCYAVTASLSRSLVQESTGGNTQIAGVVSSLLMLIMVIRIGSLFEDLPKAVLSTIVFVNLKGMFRQFMDVPLLWKTNKVDLLVWLVTFISTVLFNLDLGLALSVGFSMLTFIFKTQLPHYSILGNVPSTDLYLDTEAFKQVKEIPGIKIFRSSATICFTNAELYLEALQQRSGLDVRKLQMEKKKRAKQEKMAKKEVKKSLNKEKNLSMHKDVAIFLTNTSSNGFGHVNSAYQYDATTSEIDSGCHGENNLTPISYEHEKDGRTCMSVTHSIILDISTTGFVDTVTVKMLKNIFGDFADVDVDIYLAGCQACVVEQLEKAAFFESIPKTRLFVTVHDAVLHIL 730 HSP 2 Score: 95.9005 bits (237), Expect = 1.174e-20 Identity = 49/122 (40.16%), Postives = 76/122 (62.30%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+PL+ G+T G+A V +QLKY FGV A++ G FS+ T++ +C+ LP T +P V++ +++ +L V K IN KK+ P+PIEL+VV+ T+ + + Y + VVG I G
Sbjct: 203 YLSEPLVRGYTTGAACHVCVSQLKYLFGVKPARFTGPFSLIYTIVDICRLLPQTRVPELVVSLVALAVLIVVKE-INACYSKKLPLPVPIELIVVIGATIIIHFCGVREDYLIDVVGEIPSG 323
BLAST of STAS domain-containing protein vs. Ensembl Medaka
Match: slc26a6 (solute carrier family 26 member 6 [Source:NCBI gene;Acc:101169607]) HSP 1 Score: 161.384 bits (407), Expect = 7.677e-43 Identity = 104/316 (32.91%), Postives = 173/316 (54.75%), Query Frame = 3
Query: 363 REFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNI-HHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDE----NIFVSVHDAVI 1295
+E +A GL N F C+ + S+SRS VQE++GGKTQ+ +S ++ILF+ L+IG LF+ LP +LA++I V L+ ML +F+++ LW S D +W+ TF+ T+ L+ GL A +A S+++++ RTQ P ILG++ TD+YK + Y E+PGI IFR ++Y+A + ++++L K +D EE E+ +I +D NP++ II+D S ++D VGVK + + +Y + I V+LA + V +E +++ +F ++HDAV+
Sbjct: 368 QELVALGLSNSIGGIFQCFAISCSMSRSLVQESSGGKTQVAGALSAVVILFITLWIGTLFEDLPKAVLAAIIHVNLQGMLKQFMDIFALWKSSKIDMMIWIATFILTLLLNPDLGLAASIAFSMLTVIFRTQLPKYSILGRVEDTDIYKPLDGYSKVKELPGILIFRSSATLYFANAEMYQEALGKKEQHDN---------------------EEPEDIAVI--------HVDPEPNPSLPQAIILDLSPVNFLDTVGVKTIRNIRRDYGEIGIEVVLAACQPGVVD---NLEAGGFFNEKVTKSCLFSTIHDAVL 651 HSP 2 Score: 98.5969 bits (244), Expect = 1.179e-21 Identity = 54/122 (44.26%), Postives = 77/122 (63.11%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLS+PL+ G+T +AI V +QLKY FG++ +Y G S+ T+I +C LP TNI T V+T ++I+ L + K +N L KKI PIP EL+ ++ T+ S +DL KY + VVG I G
Sbjct: 199 YLSEPLVRGYTTAAAIHVIVSQLKYSFGISPDRYSGPLSLIYTVIEICYLLPKTNIGTLVVTLVAILGLFLAKE-LNAYLSKKIPVPIPTELIAIIIATIVSWQVDLSGKYGIDVVGEIPSG 319
BLAST of STAS domain-containing protein vs. Planmine SMEST
Match: SMESG000064566.1 (SMESG000064566.1) HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0 Identity = 322/325 (99.08%), Postives = 325/325 (100.00%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDHKIQIECL 1334
T+EFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITSLVSVILILFVLLFIGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRI+KIQKKIKKINQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLY+HKIQIECL
Sbjct: 303 TQEFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITSLVSVILILFVLLFIGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRIEKIQKKIKKINQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYNHKIQIECL 627 HSP 2 Score: 243.432 bits (620), Expect = 1.710e-73 Identity = 122/122 (100.00%), Postives = 122/122 (100.00%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG
Sbjct: 134 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 255
BLAST of STAS domain-containing protein vs. Planmine SMEST
Match: SMESG000064571.1 (SMESG000064571.1) HSP 1 Score: 452.981 bits (1164), Expect = 1.420e-154 Identity = 243/265 (91.70%), Postives = 258/265 (97.36%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQV 1154
T+EFIAFGLMNIFSSFFYCYPS SVSRSAVQE+AGGKTQITSLVS +LILFVLLFIGPLF+ LPNC+LASVIIVALKSMLMKFVELKELWLFSIWDFSVW++TFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNS+ILGQISGTDLYKNVAVY DCHEIPGIKIFRYEGS+YYAC DHFKKSLYTKISYDPIMVKLRIQK+QKKIKKINQSLEEMENT+LI +RAVFQ+ELD+LLNP+IHHIIIDCSTWGYIDIVGVKILHQV
Sbjct: 369 TQEFIAFGLMNIFSSFFYCYPSGASVSRSAVQESAGGKTQITSLVSAVLILFVLLFIGPLFKQLPNCLLASVIIVALKSMLMKFVELKELWLFSIWDFSVWVITFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSYILGQISGTDLYKNVAVYTDCHEIPGIKIFRYEGSLYYACGDHFKKSLYTKISYDPIMVKLRIQKVQKKIKKINQSLEEMENTELIVQRAVFQKELDALLNPDIHHIIIDCSTWGYIDIVGVKILHQV 633 HSP 2 Score: 214.927 bits (546), Expect = 7.998e-63 Identity = 103/122 (84.43%), Postives = 115/122 (94.26%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFTVGSAIIVFSTQLKYCFGVTI KYYGIFSVWNT+IAVCK+LP+TN+PT VLTAISII+LAVTKNV+NPILMKKIHFPIP+ELL++V GTVSS +L LH+KYNVS+VG I QG
Sbjct: 200 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIQKYYGIFSVWNTIIAVCKELPHTNVPTMVLTAISIIILAVTKNVVNPILMKKIHFPIPVELLLIVTGTVSSHFLRLHDKYNVSIVGNIDQG 321
BLAST of STAS domain-containing protein vs. Planmine SMEST
Match: SMESG000064571.1 (SMESG000064571.1) HSP 1 Score: 413.305 bits (1061), Expect = 9.432e-140 Identity = 229/265 (86.42%), Postives = 242/265 (91.32%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQV 1154
T+EFIAFGLMNIFSSFFYCYPS SVSRSAVQE+AGGKTQITSLVS +LILFVLLFIGPLF+ LPNC+LASVIIVALKSMLMKFVELKELWLFSIWDF YGLIAGVALSIISIVLRTQSPNS+ILGQISGTDLYKNVAVY DCHEIPGIKIFRYEGS+YYAC DHFKKSLYTKISYDPIMVKLRIQK+QKKIKKINQSLEEMENT+LI +RAVFQ+ELD+LLNP+IHHIIIDCSTWGYIDIVGVKILHQV
Sbjct: 332 TQEFIAFGLMNIFSSFFYCYPSGASVSRSAVQESAGGKTQITSLVSAVLILFVLLFIGPLFKQLPNCLLASVIIVALKSMLMKFVELKELWLFSIWDF----------------YGLIAGVALSIISIVLRTQSPNSYILGQISGTDLYKNVAVYTDCHEIPGIKIFRYEGSLYYACGDHFKKSLYTKISYDPIMVKLRIQKVQKKIKKINQSLEEMENTELIVQRAVFQKELDALLNPDIHHIIIDCSTWGYIDIVGVKILHQV 580 HSP 2 Score: 214.157 bits (544), Expect = 5.819e-63 Identity = 103/122 (84.43%), Postives = 115/122 (94.26%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFTVGSAIIVFSTQLKYCFGVTI KYYGIFSVWNT+IAVCK+LP+TN+PT VLTAISII+LAVTKNV+NPILMKKIHFPIP+ELL++V GTVSS +L LH+KYNVS+VG I QG
Sbjct: 163 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIQKYYGIFSVWNTIIAVCKELPHTNVPTMVLTAISIIILAVTKNVVNPILMKKIHFPIPVELLLIVTGTVSSHFLRLHDKYNVSIVGNIDQG 284
BLAST of STAS domain-containing protein vs. Planmine SMEST
Match: SMESG000064562.1 (SMESG000064562.1) HSP 1 Score: 404.445 bits (1038), Expect = 3.228e-134 Identity = 210/321 (65.42%), Postives = 260/321 (81.00%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGDCHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDHKIQ 1322
+E IA+G+MN +SFF CYPSA S+SRSAVQE+ GGKTQ+TSLVS L+LFVLLFIGP+F LPNCIL+++IIVALK M M+F ELKELWLFSIWDFS W+V FL T F+DV+YGL+ G+ SI+ I+LRTQ+P SHILGQI GTDLYKNV VY +C EI GIKIFRYEGS+YYAC D+FK SLY KISY+P ++KLRI K+++K+KK+ Q EN+ ++A + EL+ L +P IHH+IIDCSTWGYID VGVK L+QVIEEYK++NI+VLLANPKTDVR +R + S +I D IFVSVHDAVINS+Y+ K++
Sbjct: 411 NQELIAYGIMNFVASFFLCYPSASSLSRSAVQESVGGKTQLTSLVSSFLLLFVLLFIGPVFHTLPNCILSAIIIVALKGMFMQFAELKELWLFSIWDFSTWVVAFLGTAFIDVEYGLMIGIGFSILMIMLRTQNPKSHILGQIKGTDLYKNVEVYNECEEIDGIKIFRYEGSLYYACSDNFKSSLYNKISYNPRLIKLRILKLERKLKKLKQHNNNFENSPFFEEKAQLETELEKLKHPIIHHLIIDCSTWGYIDYVGVKTLNQVIEEYKSINITVLLANPKTDVRATIFRNDASSIIDDRIIFVSVHDAVINSVYERKME 731 HSP 2 Score: 125.561 bits (314), Expect = 1.471e-30 Identity = 69/122 (56.56%), Postives = 92/122 (75.41%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFTVG+++ VF++Q+KYCFG+ I K +G+F++ T + K LP TNIPT VLT + II+L VTK INP ++KKI PIP+EL+VV+ GTV S+YL L+ + V +VG I QG
Sbjct: 242 YLSDPLISGFTVGASMHVFTSQIKYCFGLNIPKQFGVFNIAKTYFYIAKNLPKTNIPTLVLTVVVIIVLFVTKEWINPRVVKKIRVPIPMELIVVIIGTVVSKYLLLNENHKVRIVGEISQG 363
BLAST of STAS domain-containing protein vs. Planmine SMEST
Match: SMESG000064562.1 (SMESG000064562.1) HSP 1 Score: 395.201 bits (1014), Expect = 1.650e-130 Identity = 210/332 (63.25%), Postives = 260/332 (78.31%), Query Frame = 3
Query: 360 TREFIAFGLMNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITXXXXXXXXXXXXXXXGPLFQPLPNCILASVIIVALKSMLMKFVELKELWLFSIWDFSVWMVTFLFTIFLDVQYGLIAGVALSIISIVLRTQSPNSHILGQISGTDLYKNVAVYGD-----------CHEIPGIKIFRYEGSIYYACKDHFKKSLYTKISYDPIMVKLRXXXXXXXXXXXNQSLEEMENTDLIAKRAVFQEELDSLLNPNIHHIIIDCSTWGYIDIVGVKILHQVIEEYKNVNISVLLANPKTDVRRMFYRIETSQLIHDENIFVSVHDAVINSLYDHKIQ 1322
+E IA+G+MN +SFF CYPSA S+SRSAVQE+ GGKTQ+TSLVS L+LFVLLFIGP+F LPNCIL+++IIVALK M M+F ELKELWLFSIWDFS W+V FL T F+DV+YGL+ G+ SI+ I+LRTQ+P SHILGQI GTDLYKNV VY + C EI GIKIFRYEGS+YYAC D+FK SLY KISY+P ++KLRI K+++K+KK+ Q EN+ ++A + EL+ L +P IHH+IIDCSTWGYID VGVK L+QVIEEYK++NI+VLLANPKTDVR +R + S +I D IFVSVHDAVINS+Y+ K++
Sbjct: 411 NQELIAYGIMNFVASFFLCYPSASSLSRSAVQESVGGKTQLTSLVSSFLLLFVLLFIGPVFHTLPNCILSAIIIVALKGMFMQFAELKELWLFSIWDFSTWVVAFLGTAFIDVEYGLMIGIGFSILMIMLRTQNPKSHILGQIKGTDLYKNVEVYNEFMESNCNCHFTCEEIDGIKIFRYEGSLYYACSDNFKSSLYNKISYNPRLIKLRILKLERKLKKLKQHNNNFENSPFFEEKAQLETELEKLKHPIIHHLIIDCSTWGYIDYVGVKTLNQVIEEYKSINITVLLANPKTDVRATIFRNDASSIIDDRIIFVSVHDAVINSVYERKME 742 HSP 2 Score: 125.176 bits (313), Expect = 1.768e-30 Identity = 69/122 (56.56%), Postives = 92/122 (75.41%), Query Frame = 1
Query: 1 YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQLPNTNIPTFVLTAISIILLAVTKNVINPILMKKIHFPIPIELLVVVAGTVSSQYLDLHNKYNVSVVGTIIQG 366
YLSDPLISGFTVG+++ VF++Q+KYCFG+ I K +G+F++ T + K LP TNIPT VLT + II+L VTK INP ++KKI PIP+EL+VV+ GTV S+YL L+ + V +VG I QG
Sbjct: 242 YLSDPLISGFTVGASMHVFTSQIKYCFGLNIPKQFGVFNIAKTYFYIAKNLPKTNIPTLVLTVVVIIVLFVTKEWINPRVVKKIRVPIPMELIVVIIGTVVSKYLLLNENHKVRIVGEISQG 363 The following BLAST results are available for this feature:
BLAST of STAS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of STAS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of STAS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of STAS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of STAS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of STAS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of STAS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031995 ID=SMED30031995|Name=STAS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1373bpback to top protein sequence of SMED30031995-orf-1 >SMED30031995-orf-1 ID=SMED30031995-orf-1|Name=SMED30031995-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=317bp MNIFSSFFYCYPSAGSVSRSAVQEAAGGKTQITSLVSVILILFVLLFIGPback to top protein sequence of SMED30031995-orf-2 >SMED30031995-orf-2 ID=SMED30031995-orf-2|Name=SMED30031995-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=129bp YLSDPLISGFTVGSAIIVFSTQLKYCFGVTIAKYYGIFSVWNTLIAVCKQback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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