UPF0638 protein B
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031945 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of UPF0638 protein B vs. Ensembl Human
Match: FAM228B (family with sequence similarity 228 member B [Source:HGNC Symbol;Acc:HGNC:24736]) HSP 1 Score: 49.6766 bits (117), Expect = 3.543e-6 Identity = 55/228 (24.12%), Postives = 105/228 (46.05%), Query Frame = 1 Query: 208 SSKAILQLQEKSDLEVQA---SNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIH-QNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXX----XXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFN 867 SSK L+ + +EV A + + + IL +E +++K+ +D ++ + RRKE+L +RW + P+ +++ + I+K+R +L +VN+KG + Y EY P+ + SK++ + + P +P + + E+R L+C TG I S K+ + + + R + W +P I S+ R R K++ +FN Sbjct: 19 SSKEWLEPKPLCFMEVLAKEDTEAAIQSILYKENSVIKE-LDKYLQHHAFLNARRKEMLYKRWVDCVADPLQKKIIEKVCSHKK---IKKRRQGELDGFLKHVNKKGNAFIEHYDPKEYDPFYM-SKKDPNFLKVTIPPFH----DPLKKAQYDKDNEKRTLLQCETGKIYSIKEFKEVEKVQLHSRFPQISNSRHFITPNEWLKLPTRYIESEFCRRRRLKVKVNFN 237
BLAST of UPF0638 protein B vs. Ensembl Human
Match: FAM228B (family with sequence similarity 228 member B [Source:HGNC Symbol;Acc:HGNC:24736]) HSP 1 Score: 49.6766 bits (117), Expect = 3.543e-6 Identity = 55/228 (24.12%), Postives = 105/228 (46.05%), Query Frame = 1 Query: 208 SSKAILQLQEKSDLEVQA---SNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIH-QNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXX----XXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFN 867 SSK L+ + +EV A + + + IL +E +++K+ +D ++ + RRKE+L +RW + P+ +++ + I+K+R +L +VN+KG + Y EY P+ + SK++ + + P +P + + E+R L+C TG I S K+ + + + R + W +P I S+ R R K++ +FN Sbjct: 19 SSKEWLEPKPLCFMEVLAKEDTEAAIQSILYKENSVIKE-LDKYLQHHAFLNARRKEMLYKRWVDCVADPLQKKIIEKVCSHKK---IKKRRQGELDGFLKHVNKKGNAFIEHYDPKEYDPFYM-SKKDPNFLKVTIPPFH----DPLKKAQYDKDNEKRTLLQCETGKIYSIKEFKEVEKVQLHSRFPQISNSRHFITPNEWLKLPTRYIESEFCRRRRLKVKVNFN 237
BLAST of UPF0638 protein B vs. Ensembl Zebrafish
Match: fam228a (family with sequence similarity 228 member A [Source:ZFIN;Acc:ZDB-GENE-041014-83]) HSP 1 Score: 84.3445 bits (207), Expect = 1.939e-18 Identity = 55/174 (31.61%), Postives = 92/174 (52.87%), Query Frame = 1 Query: 196 QNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKK 717 QN +S + QL E+ E Q N+I +LE E ++KD +D + R++++L++RW +N++ PI + + Q + + +QK R +H +Y+DY N KGFV L Y EY P+ + + K +TP +P S+ +RI+E+ LRC TG I ++ Sbjct: 11 QNTLSLSSKKQLLEQLRREQQEVNAITQPLLETEARLIKD-LDLYLTHKDTLNLRKRKLLHKRWTQNVWLPIQQSIQQHFMEHGYNE-MQKMRSMHAHYIDYCNAKGFVFLESYDPLEYNPFLHYFSTPQYH--KISTPA---LEDPLSLHSRTRIKEKTTILRCQTGHIYQRQ 177
BLAST of UPF0638 protein B vs. Ensembl Zebrafish
Match: fam228a (family with sequence similarity 228 member A [Source:ZFIN;Acc:ZDB-GENE-041014-83]) HSP 1 Score: 83.5741 bits (205), Expect = 3.508e-18 Identity = 55/174 (31.61%), Postives = 91/174 (52.30%), Query Frame = 1 Query: 196 QNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKK 717 QN +S + QL E+ E Q N+I +LE E +KD +D + R++++L++RW +N++ PI + + Q + + +QK R +H +Y+DY N KGFV L Y EY P+ + + K +TP +P S+ +RI+E+ LRC TG I ++ Sbjct: 11 QNTLSLSSKKQLLEQLRREQQEVNAITQPLLETEARFIKD-LDLYLTHKDTLNLRKRKLLHKRWTQNVWLPIQQSIQQHFMEHGYNE-MQKMRSMHAHYIDYCNAKGFVFLESYDPLEYNPFLHYFSTPQYH--KISTPA---LEDPLSLHSRTRIKEKTTILRCQTGHIYQRQ 177
BLAST of UPF0638 protein B vs. Ensembl Xenopus
Match: kiaa0100 (KIAA0100 [Source:Xenbase;Acc:XB-GENE-955497]) HSP 1 Score: 76.6406 bits (187), Expect = 2.896e-15 Identity = 71/260 (27.31%), Postives = 130/260 (50.00%), Query Frame = 1 Query: 94 KTVKNSRNNSAMS--VTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFN 867 K ++SR++ + + SC ++ TA + + +++++ K +Q+ D E Q + +L+ E N+ +++ + E RRKE+ ++RW + P+ + + + + +++R + YL Y N+KG L +Y S EY PY S Q S + P Q +P ++EEER L C TG I S +++ L + +P VPLGR ++ + W P+ I S++R +SR+++RG FN Sbjct: 32 KEKESSRDSGCVGRLIHSCPGARIMSTASNRKA---RDWLAQKPNIQM--IVDEENQEIRETMQNVLDAENHF-NQNLTKYLQKTENLELRRKEMQHKRWTERVSDPLQKTIQNYVDGQSARDIERRRRSVLGQYLKYCNKKGVAFLRDYDSAEYNPY---SHQLSKQYLRVFMP---QFLDPLLQYTQRKVEEERITLHCETGRIYSAREIHELNMKKLPQVPLGRHSMNGVEWVKAPFGYIESEIRQKSRQRIRGTFN 279
BLAST of UPF0638 protein B vs. Ensembl Mouse
Match: Fam228b (family with sequence similarity 228, member B [Source:MGI Symbol;Acc:MGI:2442121]) HSP 1 Score: 53.9138 bits (128), Expect = 7.170e-8 Identity = 47/175 (26.86%), Postives = 88/175 (50.29%), Query Frame = 1 Query: 208 SSKAILQLQEKSDLEVQA---SNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERL-DQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKD 720 SSK L+ Q S +E A +++ V IL RE I+K+ +D + RRKE+L ++W + P+ +++ ++ + N+ +++R N+L + N+KG + Y EY P+ + SK++ + P R +P + + +E+R L+C TG I + K+ Sbjct: 22 SSKEWLEPQSLSFMEALAKEDTDAAVQSILYRENYIMKE-LDKYLHHQDFLNTRRKEMLYKKWVERVADPLQKKIIEKVHSHKNIK---KRRRQELDNFLKHSNKKGNAFIEHYDPKEYDPFYM-SKEDPNFLKVIMPPFR----DPLKKAQYDQDDEKRTLLQCETGKIYTMKE 187
BLAST of UPF0638 protein B vs. Ensembl Mouse
Match: Fam228b (family with sequence similarity 228, member B [Source:MGI Symbol;Acc:MGI:2442121]) HSP 1 Score: 50.8322 bits (120), Expect = 3.338e-7 Identity = 45/169 (26.63%), Postives = 85/169 (50.30%), Query Frame = 1 Query: 208 SSKAILQLQEKSDLEVQA---SNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERL-DQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGS 702 SSK L+ Q S +E A +++ V IL RE I+K+ +D + RRKE+L ++W + P+ +++ ++ + N+ +++R N+L + N+KG + Y EY P+ + SK++ + P R +P + + +E+R L+C TG+ Sbjct: 22 SSKEWLEPQSLSFMEALAKEDTDAAVQSILYRENYIMKE-LDKYLHHQDFLNTRRKEMLYKKWVERVADPLQKKIIEKVHSHKNIK---KRRRQELDNFLKHSNKKGNAFIEHYDPKEYDPFYM-SKEDPNFLKVIMPPFR----DPLKKAQYDQDDEKRTLLQCETGT 181
BLAST of UPF0638 protein B vs. UniProt/SwissProt
Match: sp|A6QQ68|F228B_BOVIN (Protein FAM228B OS=Bos taurus OX=9913 GN=FAM228B PE=2 SV=1) HSP 1 Score: 64.6994 bits (156), Expect = 1.600e-10 Identity = 63/239 (26.36%), Postives = 112/239 (46.86%), Query Frame = 1 Query: 184 SEHLQNYISSKAILQLQEKSDLEVQASNSI---VGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIH-QNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLA----WSYMPYNQINSDVRTRSRKKMRGDFNYGS 876 ++ L SS+ L+ Q S +EV A + + IL RE I+K+ +D +K + RRKE+L +RW ++ P+ +++ + I+K+R +L YVN+KG + Y EY P+ + +++N + + P R +P + + + +R L+C TG I + K+ + + + G L W +P N I S+ RSR K++ +FN S Sbjct: 10 TDKLPKLKSSREWLEPQPLSFMEVLAKEDVDTAIQSILYRENYIIKE-LDKCLKHHDFLNARRKEILYKRWVDHVADPLQKKIIEKVTSYKK---IKKRRQEELDGFLKYVNKKGNAFIEHYDPKEYDPFYM-NRENPNFLKVTIPPFR----DPLKKAQYDKDDGKRILLQCETGKIYTMKEFKEVEKAKLHSRFPGISNSRHLMTPNEWIRLPPNYIESEFCKRSRLKIKVNFNESS 239
BLAST of UPF0638 protein B vs. UniProt/SwissProt
Match: sp|Q497Q6|F228B_MOUSE (Protein FAM228B OS=Mus musculus OX=10090 GN=Fam228b PE=2 SV=1) HSP 1 Score: 53.9138 bits (128), Expect = 5.015e-7 Identity = 47/175 (26.86%), Postives = 88/175 (50.29%), Query Frame = 1 Query: 208 SSKAILQLQEKSDLEVQA---SNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERL-DQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKD 720 SSK L+ Q S +E A +++ V IL RE I+K+ +D + RRKE+L ++W + P+ +++ ++ + N+ +++R N+L + N+KG + Y EY P+ + SK++ + P R +P + + +E+R L+C TG I + K+ Sbjct: 22 SSKEWLEPQSLSFMEALAKEDTDAAVQSILYRENYIMKE-LDKYLHHQDFLNTRRKEMLYKKWVERVADPLQKKIIEKVHSHKNIK---KRRRQELDNFLKHSNKKGNAFIEHYDPKEYDPFYM-SKEDPNFLKVIMPPFR----DPLKKAQYDQDDEKRTLLQCETGKIYTMKE 187
BLAST of UPF0638 protein B vs. TrEMBL
Match: A0A210QQE2 (Uncharacterized protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT07478 PE=4 SV=1) HSP 1 Score: 128.642 bits (322), Expect = 4.253e-30 Identity = 88/256 (34.38%), Postives = 145/256 (56.64%), Query Frame = 1 Query: 109 SRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSA---NPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFN 867 R + + T+ +D ++I + +Q++++ K + LQEKSD+E + + + +L+ E T VK N++ I V EQR+KE+L+++WN +++P+ + + + + + ++KR++H+ YL++ N+KG V L +EYY AL N PI+V +A +P R E+R LRC+TG + KDL+ ++LPP+PLVPLGR G D L W MP + I S R SR++MRG FN Sbjct: 45 GRKSRQGAETTNGDTGMDSQSLIGQTMRVQDWLNEKTVKGLQEKSDIETREARKLYEPLLQTEDTFVK-NLEEYITYKDVMEQRKKEMLHKKWNDRVFEPLRKNIIDAMDSDDWPELDRRKRELHKQYLEFTNQKGHVFLDTMDPEEYYAQAL--------NGHRPAPIKVSTAALRDPLLSQGRQRSAEDRTILRCITGYSYTDKDLEQVKLPPLPLVPLGRHGTDSLKWLEMPLHNIESTPRMASRRRMRGTFN 291
BLAST of UPF0638 protein B vs. TrEMBL
Match: A0A2B4SV41 (Protein FAM228B OS=Stylophora pistillata OX=50429 GN=Fam228b PE=4 SV=1) HSP 1 Score: 127.487 bits (319), Expect = 8.649e-30 Identity = 81/232 (34.91%), Postives = 138/232 (59.48%), Query Frame = 1 Query: 181 HSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSA---NPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFN 867 H+ +Q++++ K++ +QE++D E +A+ + +L+ E T VKD VD+ I + + ++R+KE+L ++W+ +Y P+ E++D+ N N ++KR I++ YLDY N+KG V L +EY P L N+ P++ + +P +R+EE+R +RC+TG +S K ++ + LPP PLVPLGR G +C W M + I+S VR RSR +M+G +N Sbjct: 71 HTFRIQSWLNEKSVRNIQERTDFESRATKKMYTTLLDNENTFVKD-VDSFIDQKEALDRRKKEMLFKKWSEQVYSPVREKIDEEMNGPNYRHLDRRKRTIYKKYLDYSNKKGVVFLDVMSPEEYDPLVL--------NANRPAPLKAITQKLDDPLLSQGTTRLEEDRTMVRCITGDTMSDKQIEEIHLPPAPLVPLGRHGTECNTWLRMQLHDIDSGVRKRSRLRMKGLYN 293
BLAST of UPF0638 protein B vs. TrEMBL
Match: A0A433T605 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_015228 PE=4 SV=1) HSP 1 Score: 126.716 bits (317), Expect = 2.712e-29 Identity = 94/292 (32.19%), Postives = 164/292 (56.16%), Query Frame = 1 Query: 103 KNSRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSAN---PTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRG-----DFNYGSAFASLTETSKV----FQLPTRYAVSE 942 K S ++ + S ++ +D ++ S +Q++++ K I +LQE +D E QA+ + LE E T +K+ D + + V+ R+KEVL++RW+ +Y+PI +++ ++ + ++ ++KR++H+ +L++VN++GFV L + +EYY AL N PI++++ N P R EE+R +RC TG S DL +RLPP+PL+PLGR G++ W MP I S VR RSR +M G D ++ +A++ + +K+ Q+P R A +E Sbjct: 47 KKSDIRASSAPDSASTVSMDSKGLLSQSVRVQDWLNEKTIKELQEGTDHESQAAKKLYAPFLETESTFIKEIGDRLAYKELVD-LRKKEVLHKRWSDQVYEPIRKKILEAIDGADWHHLDRRKREMHKQFLEHVNKRGFVFLEDDDREEYYAQAL--------NGHRPNPIKIRTENLSDPLLTLSRQRSEEDRTIMRCTTGQNYSDNDLDQVRLPPLPLIPLGRHGINSCRWLEMPLTNIESPVRERSRLRMLGNSTKTDIDF-AAWSKMGRDAKIVARELQIPRRKAFAE 328
BLAST of UPF0638 protein B vs. TrEMBL
Match: A0A1S3KGX9 (protein FAM228B isoform X1 OS=Lingula unguis OX=7574 GN=LOC106181908 PE=4 SV=1) HSP 1 Score: 123.635 bits (309), Expect = 1.763e-28 Identity = 81/242 (33.47%), Postives = 139/242 (57.44%), Query Frame = 1 Query: 157 LDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKS----NTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFNY 870 +D ++I H+ LQ+++S K++ ++QE++D+E + + + +L+ E VKD +D + +V++ R+KE+L+++WN +++PI + + + ++KR I++ YL++ N+KG V L EY P L N ++ P+R +P R EE+R LRC TG + KD++ ++LPP+PLVPLGR G +C W MP + I S VR SR +MRGD+N+ Sbjct: 65 VDSDSLIGHTLKLQDWLSEKSVKEIQERADIEARDTKKMYNSVLDVEDNFVKD-IDAFLAAKEVHDLRKKEILHKKWNDQVHEPIRKEVIKEMGGPAYKQLDRRKRQIYKEYLEFTNQKGHVFLDTVDPAEYCPLGLHV--NRPLGTRGIHAETKPLR----DPLLSQAKERAEEDRTILRCTTGITYTDKDIEKIKLPPLPLVPLGRHGTECKTWLAMPMHDIESPVRKASRGRMRGDYNH 299
BLAST of UPF0638 protein B vs. TrEMBL
Match: A7SC67 (Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g112977 PE=4 SV=1) HSP 1 Score: 116.701 bits (291), Expect = 6.347e-27 Identity = 82/231 (35.50%), Postives = 139/231 (60.17%), Query Frame = 1 Query: 193 LQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDE------NSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFN 867 +QN+++ K++ +QE++D E +A+ ++ +LE E + VK+ VD + + ++R+K++L+++W+ +Y P+ E++DQ N N ++KR I+++YLDY N KG V L +EY P AL N P++ A T +D+ +R EE+R +L C+TG + K+++++R PP PLVPLGRQG +C W M + I+SDVR RS +M+G +N Sbjct: 12 IQNWLNEKSVRGIQERTDFESRATRNMYTTLLENEDSFVKE-VDGYLHYKSMLDRRKKQLLHKKWSERVYFPVKEQIDQEMNGPNYKNLDKRKRTIYKHYLDYSNNKGVVFLDVMSPEEYDPLAL--------NKNRPGPLK---AITTKLDDCLISQGATRSEEDRIELGCITGERMPDKEIENIRKPPPPLVPLGRQGTECKTWLRMQLHDIDSDVRMRSGLRMKGTYN 230
BLAST of UPF0638 protein B vs. Ensembl Cavefish
Match: ENSAMXT00000041201.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:25037552:25044118:-1 gene:ENSAMXG00000036485.1 transcript:ENSAMXT00000041201.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 59.6918 bits (143), Expect = 5.934e-10 Identity = 50/194 (25.77%), Postives = 93/194 (47.94%), Query Frame = 1 Query: 127 MSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYAL-FSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSI 705 MSV S T + ++ +Q + + +LQE+ E + ++ I +L+ E +KD ++ + R++ +L+++W +++PI + + + ++ + R + +Y+DY N KGFVSL Y S EY P+ L K NS + +TP +P + SR+ E R RC +G + Sbjct: 1 MSVAGSDSATRAVTHLKTSADLMQTHFPC-TVKKLQEQFFSEQREADLITQPLLDTENRFIKD-LELYLDHRDKLALRKRGLLHKQWTDCVWQPIQQSIKRRFTHASFK-GAKPIRMMMTHYIDYCNTKGFVSLESYDSREYDPFLLRICKPNSY---QVSTP---SLKDPLCLQSRSRMRENRAITRCQSGCV 185
BLAST of UPF0638 protein B vs. Ensembl Cavefish
Match: ENSAMXT00000044494.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:25037552:25044880:-1 gene:ENSAMXG00000036485.1 transcript:ENSAMXT00000044494.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 59.6918 bits (143), Expect = 5.934e-10 Identity = 50/194 (25.77%), Postives = 93/194 (47.94%), Query Frame = 1 Query: 127 MSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYAL-FSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSI 705 MSV S T + ++ +Q + + +LQE+ E + ++ I +L+ E +KD ++ + R++ +L+++W +++PI + + + ++ + R + +Y+DY N KGFVSL Y S EY P+ L K NS + +TP +P + SR+ E R RC +G + Sbjct: 1 MSVAGSDSATRAVTHLKTSADLMQTHFPC-TVKKLQEQFFSEQREADLITQPLLDTENRFIKD-LELYLDHRDKLALRKRGLLHKQWTDCVWQPIQQSIKRRFTHASFK-GAKPIRMMMTHYIDYCNTKGFVSLESYDSREYDPFLLRICKPNSY---QVSTP---SLKDPLCLQSRSRMRENRAITRCQSGCV 185
BLAST of UPF0638 protein B vs. Ensembl Nematostella
Match: EDO38688 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC67]) HSP 1 Score: 116.701 bits (291), Expect = 8.777e-31 Identity = 82/231 (35.50%), Postives = 139/231 (60.17%), Query Frame = 1 Query: 193 LQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDE------NSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFN 867 +QN+++ K++ +QE++D E +A+ ++ +LE E + VK+ VD + + ++R+K++L+++W+ +Y P+ E++DQ N N ++KR I+++YLDY N KG V L +EY P AL N P++ A T +D+ +R EE+R +L C+TG + K+++++R PP PLVPLGRQG +C W M + I+SDVR RS +M+G +N Sbjct: 12 IQNWLNEKSVRGIQERTDFESRATRNMYTTLLENEDSFVKE-VDGYLHYKSMLDRRKKQLLHKKWSERVYFPVKEQIDQEMNGPNYKNLDKRKRTIYKHYLDYSNNKGVVFLDVMSPEEYDPLAL--------NKNRPGPLK---AITTKLDDCLISQGATRSEEDRIELGCITGERMPDKEIENIRKPPPPLVPLGRQGTECKTWLRMQLHDIDSDVRMRSGLRMKGTYN 230
BLAST of UPF0638 protein B vs. Planmine SMEST
Match: SMESG000003269.1 (SMESG000003269.1) HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0 Identity = 288/293 (98.29%), Postives = 291/293 (99.32%), Query Frame = 1 Query: 91 MKTVKNSRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAVSEASEGIDDVF 969 MKTVKNSRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIY+PI+ERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDEN RIEEERCQLRCLTGSILSKKDLQSLRLPPVPLVPLGRQGVDCLAWSYMP+NQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAV EASEGIDDVF Sbjct: 1 MKTVKNSRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYEPIAERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENFRIEEERCQLRCLTGSILSKKDLQSLRLPPVPLVPLGRQGVDCLAWSYMPHNQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAVLEASEGIDDVF 293
BLAST of UPF0638 protein B vs. Planmine SMEST
Match: SMESG000003269.1 (SMESG000003269.1) HSP 1 Score: 537.339 bits (1383), Expect = 0.000e+0 Identity = 282/288 (97.92%), Postives = 286/288 (99.31%), Query Frame = 1 Query: 106 NSRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAVSEASEGIDDVF 969 N+RNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIY+PI+ERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDEN RIEEERCQLRCLTGSILSKKDLQSLRLPPVPLVPLGRQGVDCLAWSYMP+NQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAV EASEGIDDVF Sbjct: 16 NNRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYEPIAERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENFRIEEERCQLRCLTGSILSKKDLQSLRLPPVPLVPLGRQGVDCLAWSYMPHNQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAVLEASEGIDDVF 303
BLAST of UPF0638 protein B vs. Planmine SMEST
Match: SMESG000003269.1 (SMESG000003269.1) HSP 1 Score: 524.628 bits (1350), Expect = 0.000e+0 Identity = 276/281 (98.22%), Postives = 279/281 (99.29%), Query Frame = 1 Query: 127 MSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYKPISERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENSRIEEERCQLRCLTGSILSKKDXXXXXXXXXXXXXXXXXXVDCLAWSYMPYNQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAVSEASEGIDDVF 969 MSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIY+PI+ERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDEN RIEEERCQLRCLTGSILSKKDLQSLRLPPVPLVPLGRQGVDCLAWSYMP+NQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAV EASEGIDDVF Sbjct: 1 MSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKSDLEVQASNSIVGEILEREKTIVKDNVDNIIKEYQVNEQRRKEVLNRRWNRNIYEPIAERLDQSRNDSNLDIFIQKKRDIHQNYLDYVNRKGFVSLSEYCSDEYYPYALFSKQNSVYNSKSNTPIRVQSANPTSVDENFRIEEERCQLRCLTGSILSKKDLQSLRLPPVPLVPLGRQGVDCLAWSYMPHNQINSDVRTRSRKKMRGDFNYGSAFASLTETSKVFQLPTRYAVLEASEGIDDVF 281 The following BLAST results are available for this feature:
BLAST of UPF0638 protein B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of UPF0638 protein B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of UPF0638 protein B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of UPF0638 protein B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of UPF0638 protein B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of UPF0638 protein B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 2
BLAST of UPF0638 protein B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 2
BLAST of UPF0638 protein B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of UPF0638 protein B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of UPF0638 protein B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of UPF0638 protein B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of UPF0638 protein B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of UPF0638 protein B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of UPF0638 protein B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031945 ID=SMED30031945|Name=UPF0638 protein B|organism=Schmidtea mediterranea sexual|type=transcript|length=1081bpback to top protein sequence of SMED30031945-orf-1 >SMED30031945-orf-1 ID=SMED30031945-orf-1|Name=SMED30031945-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=294bp MKTVKNSRNNSAMSVTSCASFKLDPTAMIKHSEHLQNYISSKAILQLQEKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|