zf-LYAR domain-containing protein

Overview
Namezf-LYAR domain-containing protein
Smed IDSMED30031929
Length (bp)1818
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of zf-LYAR domain-containing protein (SMED30031929) t-SNE clustered cells

Violin plots show distribution of expression levels for zf-LYAR domain-containing protein (SMED30031929) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of zf-LYAR domain-containing protein (SMED30031929) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for zf-LYAR domain-containing protein (SMED30031929) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031929

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30031929SMESG000081140.1 SmedASXL_010220SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
pharynxSMED30031929SMESG000081140.1 dd_Smed_v4_5281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30031929SMESG000081140.1 dd_Smed_v4_5281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30031929SMESG000081140.1 dd_Smed_v4_5281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30031929SMESG000081140.1 dd_Smed_v4_5281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30031929SMESG000081140.1 dd_Smed_v4_5281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30031929SMESG000081140.1 dd_Smed_v4_5281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30031929SMESG000081140.1 dd_Smed_v4_5281_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30031929SMESG000081140.1 SMESG000057533.1 Contig50398newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30031929SMESG000081140.1 SMESG000057533.1 Contig50398uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30031929SMESG000081140.1 SMED30031929smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30031929SMESG000081140.1 SMED30031929smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30031929SMESG000081140.1 dd_Smed_v6_5281_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Human
Match: LYAR (Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC:26021])

HSP 1 Score: 59.6918 bits (143), Expect = 8.058e-9
Identity = 37/125 (29.60%), Postives = 63/125 (50.40%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKL 433
            MV F C++C  S++  QV  H    +     SC+ C  +F   + K+HVKCISE +KY G  +      +K   K+  W   I+E +     +   +++++  I    N+P K+  F N++K+ L
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGK--THKGDIKQQAWIQKISELIKRPNVS-PKVRELLEQISAFDNVPRKKAKFQNWMKNSL 122
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Human
Match: LYAR (Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC:26021])

HSP 1 Score: 59.6918 bits (143), Expect = 8.058e-9
Identity = 37/125 (29.60%), Postives = 63/125 (50.40%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKL 433
            MV F C++C  S++  QV  H    +     SC+ C  +F   + K+HVKCISE +KY G  +      +K   K+  W   I+E +     +   +++++  I    N+P K+  F N++K+ L
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGK--THKGDIKQQAWIQKISELIKRPNVS-PKVRELLEQISAFDNVPRKKAKFQNWMKNSL 122
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Human
Match: LYAR (Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC:26021])

HSP 1 Score: 45.8246 bits (107), Expect = 8.486e-6
Identity = 24/60 (40.00%), Postives = 34/60 (56.67%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKG 238
            MV F C++C  S++  QV  H    +     SC+ C  +F   + K+HVKCISE +KY G
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGG 60
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Celegans
Match: C16C10.8 (pep chromosome:WBcel235:III:4161951:4164171:-1 gene:WBGene00007628.1 transcript:C16C10.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C16C10.8)

HSP 1 Score: 75.485 bits (184), Expect = 4.779e-15
Identity = 50/150 (33.33%), Postives = 81/150 (54.00%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH--SC-NSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALK 511
            MV F C++C  + + NQV  H   C N+ FSC+ C + ++++  K HVKCI+E +KY G ++   + ENK   K+N W + +N  +     TDS +++++ S+    NIP KE  F NF+ +      L   N A   W  I+   D ++
Sbjct:    1 MVFFSCNNCGEACKKNQVERHLFQCRNTTFSCIDCQLVYTRETYKDHVKCITENQKYGGKNY--VEKENKGEAKQNAWVDQVNRAIEF--VTDSQVKELLKSVAGFANIPRKEAKFINFLTNSCR---LRDKNLALRAWQAIAAEADKMR 143
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Fly
Match: CG12909 (gene:FBgn0033507 transcript:FBtr0088348)

HSP 1 Score: 65.855 bits (159), Expect = 1.895e-11
Identity = 59/193 (30.57%), Postives = 95/193 (49.22%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH---SCNSK---FSCLSCNMEFSQQNVKSHVKCISEAEKY--KGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIAS----IKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS----PLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKK 601
            MV F C+ C  S++   V  H    C  K    SC+ C  +F  +   +H+KCISEA+KY  +   F A +  NKN +K+ +W + I   L+S E    NL   + S    +++  N+P K+  F NFV    G  +    N A  +W ++      +K+A +  ++  K  ++    QK+K E +EE+  KK
Sbjct:    1 MVFFTCNICGESVKKPAVEKHYQTRCRGKDKNVSCMDCLKDFYGEEYVAHIKCISEAQKYASQSQGFAAKEPRNKNAQKQESWMDIIRSILDSSEY---NLTPAVRSAFQKLQSVDNVPRKKAKFENFV----GNCMRMPRNQATQVWDILEKELNKMKEAKQAELARAKAEKIAEIQQKQKAEVEEEAPPKK 186
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Xenopus
Match: kctd5 (potassium channel tetramerization domain containing 5 [Source:Xenbase;Acc:XB-GENE-1016270])

HSP 1 Score: 65.4698 bits (158), Expect = 7.336e-11
Identity = 40/125 (32.00%), Postives = 64/125 (51.20%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKL 433
            MV F C++C  SL+  QV  H    +     SC+ C  +F   + ++H+KCISE +KY G  F A    NK   K+  W   I E +     +  N++ ++  + +  NIP K+  F N++K+ L
Sbjct:    1 MVFFTCNACGESLKKGQVEKHRGKCRNCGCLSCIDCGKDFWGDDYQNHLKCISEDQKYGGKAFEAK--ANKGDVKQQQWLERIQEIMKKPNIS-PNIRNILNQMSSYENIPRKKAKFQNWMKNSL 122
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Xenopus
Match: kctd5 (potassium channel tetramerization domain containing 5 [Source:Xenbase;Acc:XB-GENE-1016270])

HSP 1 Score: 65.4698 bits (158), Expect = 8.507e-11
Identity = 40/125 (32.00%), Postives = 64/125 (51.20%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKL 433
            MV F C++C  SL+  QV  H    +     SC+ C  +F   + ++H+KCISE +KY G  F A    NK   K+  W   I E +     +  N++ ++  + +  NIP K+  F N++K+ L
Sbjct:    1 MVFFTCNACGESLKKGQVEKHRGKCRNCGCLSCIDCGKDFWGDDYQNHLKCISEDQKYGGKAFEAK--ANKGDVKQQQWLERIQEIMKKPNIS-PNIRNILNQMSSYENIPRKKAKFQNWMKNSL 122
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Mouse
Match: Lyar (Ly1 antibody reactive clone [Source:MGI Symbol;Acc:MGI:107470])

HSP 1 Score: 70.0922 bits (170), Expect = 2.450e-13
Identity = 44/144 (30.56%), Postives = 75/144 (52.08%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS 490
            MV F C++C  S++  QV  H  N +     SC+ C  +F   + KSHVKCISE +KY G  + A    +K   K+  W   INE +     +   +++++  I    N+P K+  F N++K+ L    ++S++  + +W + S
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEA--KTHKGDAKQQAWIQKINELIKKPNVS-PKVRELLQQISAFDNVPRKKAKFQNWMKNSLK---VHSDSVLEQVWDIFS 138
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Mouse
Match: Lyar (Ly1 antibody reactive clone [Source:MGI Symbol;Acc:MGI:107470])

HSP 1 Score: 69.707 bits (169), Expect = 2.879e-13
Identity = 44/144 (30.56%), Postives = 75/144 (52.08%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS 490
            MV F C++C  S++  QV  H  N +     SC+ C  +F   + KSHVKCISE +KY G  + A    +K   K+  W   INE +     +   +++++  I    N+P K+  F N++K+ L    ++S++  + +W + S
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEA--KTHKGDAKQQAWIQKINELIKKPNVS-PKVRELLQQISAFDNVPRKKAKFQNWMKNSLK---VHSDSVLEQVWDIFS 138
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Mouse
Match: Lyar (Ly1 antibody reactive clone [Source:MGI Symbol;Acc:MGI:107470])

HSP 1 Score: 72.4034 bits (176), Expect = 4.261e-13
Identity = 44/144 (30.56%), Postives = 75/144 (52.08%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS 490
            MV F C++C  S++  QV  H  N +     SC+ C  +F   + KSHVKCISE +KY G  + A    +K   K+  W   INE +     +   +++++  I    N+P K+  F N++K+ L    ++S++  + +W + S
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEA--KTHKGDAKQQAWIQKINELIKKPNVS-PKVRELLQQISAFDNVPRKKAKFQNWMKNSL---KVHSDSVLEQVWDIFS 138
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Mouse
Match: Lyar (Ly1 antibody reactive clone [Source:MGI Symbol;Acc:MGI:107470])

HSP 1 Score: 72.4034 bits (176), Expect = 4.261e-13
Identity = 44/144 (30.56%), Postives = 75/144 (52.08%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS 490
            MV F C++C  S++  QV  H  N +     SC+ C  +F   + KSHVKCISE +KY G  + A    +K   K+  W   INE +     +   +++++  I    N+P K+  F N++K+ L    ++S++  + +W + S
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEA--KTHKGDAKQQAWIQKINELIKKPNVS-PKVRELLQQISAFDNVPRKKAKFQNWMKNSL---KVHSDSVLEQVWDIFS 138
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Mouse
Match: Lyar (Ly1 antibody reactive clone [Source:MGI Symbol;Acc:MGI:107470])

HSP 1 Score: 64.6994 bits (156), Expect = 4.661e-12
Identity = 41/125 (32.80%), Postives = 64/125 (51.20%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKL 433
            MV F C++C  S++  QV  H  N +     SC+ C  +F   + KSHVKCISE +KY G  + A    +K   K+  W   INE +         +++++  I    N+P K+  F N++K+ L
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEAK--THKGDAKQQAWIQKINELIKK-PNVSPKVRELLQQISAFDNVPRKKAKFQNWMKNSL 122
[Close]
BLAST of zf-LYAR domain-containing protein vs. UniProt/SwissProt
Match: sp|Q09464|YQ58_CAEEL (Uncharacterized protein C16C10.8 OS=Caenorhabditis elegans OX=6239 GN=C16C10.8 PE=4 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 6.080e-14
Identity = 50/150 (33.33%), Postives = 81/150 (54.00%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH--SC-NSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALK 511
            MV F C++C  + + NQV  H   C N+ FSC+ C + ++++  K HVKCI+E +KY G ++   + ENK   K+N W + +N  +     TDS +++++ S+    NIP KE  F NF+ +      L   N A   W  I+   D ++
Sbjct:    1 MVFFSCNNCGEACKKNQVERHLFQCRNTTFSCIDCQLVYTRETYKDHVKCITENQKYGGKNY--VEKENKGEAKQNAWVDQVNRAIEF--VTDSQVKELLKSVAGFANIPRKEAKFINFLTNSCR---LRDKNLALRAWQAIAAEADKMR 143
[Close]
BLAST of zf-LYAR domain-containing protein vs. UniProt/SwissProt
Match: sp|Q08288|LYAR_MOUSE (Cell growth-regulating nucleolar protein OS=Mus musculus OX=10090 GN=Lyar PE=1 SV=2)

HSP 1 Score: 72.4034 bits (176), Expect = 2.981e-12
Identity = 44/144 (30.56%), Postives = 75/144 (52.08%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS 490
            MV F C++C  S++  QV  H  N +     SC+ C  +F   + KSHVKCISE +KY G  + A    +K   K+  W   INE +     +   +++++  I    N+P K+  F N++K+ L    ++S++  + +W + S
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEA--KTHKGDAKQQAWIQKINELIKKPNVS-PKVRELLQQISAFDNVPRKKAKFQNWMKNSL---KVHSDSVLEQVWDIFS 138
[Close]
BLAST of zf-LYAR domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6AYK5|LYAR_RAT (Cell growth-regulating nucleolar protein OS=Rattus norvegicus OX=10116 GN=Lyar PE=1 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 7.821e-10
Identity = 42/145 (28.97%), Postives = 75/145 (51.72%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH-----SCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS 490
            MV F C++C  S++  QV  H     +C    SC+ C  +F   + K+HVKCISE +KY G  + A    +K   K+  W   INE +     +   +++++  I    N+P K+  F N++++ L    ++S++  + +W + S
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSICRNCEC-LSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEA--KTHKGDVKQQAWIQKINELIKKPNVS-PKVRELLQQISAFDNVPRKKAKFQNWMRNSL---KVHSDSVLEQVWNIFS 138
[Close]
BLAST of zf-LYAR domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NX58|LYAR_HUMAN (Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2)

HSP 1 Score: 59.3066 bits (142), Expect = 4.191e-8
Identity = 37/125 (29.60%), Postives = 63/125 (50.40%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKL 433
            MV F C++C  S++  QV  H    +     SC+ C  +F   + K+HVKCISE +KY G  +      +K   K+  W   I+E +     +   +++++  I    N+P K+  F N++K+ L
Sbjct:    1 MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGK--THKGDIKQQAWIQKISELIKRPNVS-PKVRELLEQISAFDNVPRKKAKFQNWMKNSL 122
[Close]
BLAST of zf-LYAR domain-containing protein vs. TrEMBL
Match: L7MKM7 (Putative cell growth-regulating nucleolar protein (Fragment) OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 2.676e-15
Identity = 51/154 (33.12%), Postives = 84/154 (54.55%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH------SCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKK 514
            MVVF C++C  SL+ NQV  H      SCN   +C+ CN +F     K H+KC++EAE+Y G +F       K   K+  W   +++ + + E +   ++ V   ++N  N+P KEKPF NF++S +G   + + + A+ +W  I   +  L+K
Sbjct:    1 MVVFTCNTCGDSLKKNQVEKHVYTKCRSCNM-LTCIDCNKDFWGDAYKEHIKCVTEAERYGGKNFKPQ--TFKGEAKQQEWTELLSKIIETQEMSPP-VKDVFKRMQNFNNVPRKEKPFKNFLQSSMG---VRNPSLAQDVWQTIQKAQQTLQK 147
[Close]
BLAST of zf-LYAR domain-containing protein vs. TrEMBL
Match: A0A0N8BIM4 (Cell growth-regulating nucleolar protein OS=Daphnia magna OX=35525 GN=APZ42_028360 PE=4 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 3.415e-15
Identity = 63/187 (33.69%), Postives = 93/187 (49.73%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSK----FSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKKIKKDTE 619
            MV FVC+ C +S++ NQV  H    +     SC+ C+ +F  Q  K+H+KC+SE EKY G D+ A  N+NKN  K+  W   I   +     T+  L   +  I    NIP K+  F NF+K+ LG  V       + +W +IS   + L+   +   NN     A+K +    EE+  K+ K D E
Sbjct:    1 MVFFVCNGCGTSVKKNQVEKHQYQCRRSQHLSCVDCSKDFIGQEYKAHIKCVSEEEKYSGKDYVAKPNQNKNERKQTEWVAMIQNLVEKVGNTNDELSSALQRISQHENIPRKKPKFINFLKNILGNRV--PPRITEQLWDLISKEIEELRVSKAPNVNNSSTKVAEKTEKTSDEENGIKR-KHDGE 184
[Close]
BLAST of zf-LYAR domain-containing protein vs. TrEMBL
Match: L7M4C7 (Putative cell growth-regulating nucleolar protein OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 4.414e-15
Identity = 51/154 (33.12%), Postives = 84/154 (54.55%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH------SCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKK 514
            MVVF C++C  SL+ NQV  H      SCN   +C+ CN +F     K H+KC++EAE+Y G +F       K   K+  W   +++ + + E +   ++ V   ++N  N+P KEKPF NF++S +G   + + + A+ +W  I   +  L+K
Sbjct:    1 MVVFTCNTCGDSLKKNQVEKHVYTKCRSCNM-LTCIDCNKDFWGDAYKEHIKCVTEAERYGGKNFKPQ--TFKGEAKQQEWTELLSKIIETQEMSPP-VKDVFKRMQNFNNVPRKEKPFKNFLQSSMG---VRNPSLAQDVWQTIQKAQQTLQK 147
[Close]
BLAST of zf-LYAR domain-containing protein vs. TrEMBL
Match: A0A131XFB0 (Putative cell growth-regulating nucleolar protein OS=Hyalomma excavatum OX=257692 PE=2 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 4.622e-15
Identity = 51/154 (33.12%), Postives = 84/154 (54.55%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH------SCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKK 514
            MVVF C++C  SL+ NQV  H      +CN   +C+ CN +F     K H KC++EAE+Y G +F       K   K+  W   +++ + + E +   +++V   ++N  N+P KEKPF NF++S +G   + +   A+ +W  I   + AL+K
Sbjct:    1 MVVFTCNTCGDSLKKNQVEKHVYTKCRNCNL-LTCIDCNKDFWGDAYKEHFKCVTEAERYGGKNFKPQ--TFKGEVKQQEWTELLSKIIETQEMSPP-VKEVFKRMQNYNNVPRKEKPFKNFLQSSMG---VRNQALAQDVWQTIQKAQQALQK 147
[Close]
BLAST of zf-LYAR domain-containing protein vs. TrEMBL
Match: A0A0L8IAX6 (zf-LYAR domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22026918mg PE=4 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 4.727e-15
Identity = 73/214 (34.11%), Postives = 107/214 (50.00%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH--SCN-SKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKKIKK--DTELPE--TKKKSTRSDNKLKAENNNKIE 691
            MV F CS+C+ SL+ NQV  H   C  S  SCL CN EF      SH+KCISE EKY G D+ A   +NK   K++ W   +   ++    +  N++ ++  +K+ PNIP K+  F NF+ + L    +   +  K IW ++            +T+    + E  +RK    E SVT   +K  D E+ E  TKK+S R     ++E  NK E
Sbjct:    1 MVFFSCSNCSESLKKNQVNKHYIRCRMSMVSCLDCNKEFWGDEFNSHIKCISEEEKYSGKDYKARPTQNKGEAKQDAWIQKVQTAIDK-SNSKPNIRNLLERLKDYPNIPRKQTKFENFLHNSL---RVRDQSLVKEIWDIL------------MTEKTSESKEVDERK---DETSVTNGEEKSVDGEIDENKTKKESKREKKAKRSEKQNKKE 195
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Cavefish
Match: lyar (Ly1 antibody reactive homolog (mouse) [Source:ZFIN;Acc:ZDB-GENE-040426-1414])

HSP 1 Score: 68.9366 bits (167), Expect = 3.199e-12
Identity = 49/151 (32.45%), Postives = 76/151 (50.33%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH----SCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALK 511
            MV F C+SC  SL+  Q+  H      +S FSC+ C  +F  +  K+H++CISE +KY G  + A    NK   K+  W   I E L S       L+ ++  I +  N+P K+  F N++K  L    LN  N    +W +IS  + +++
Sbjct:    1 MVFFTCNSCGESLKKAQIEKHVGMCRGSSCFSCIDCGKDFWGEEYKNHLRCISEDQKYGGRGYEAK--ANKGDVKQQQWIQRIQEAL-SKPGVSVRLKDLLNQICSYDNVPRKKAKFQNWIKCSLKIHDLNLQNQ---VWEIISAAESSVQ 145
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Sea Lamprey
Match: LYAR (Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC:26021])

HSP 1 Score: 70.4774 bits (171), Expect = 2.789e-13
Identity = 43/144 (29.86%), Postives = 73/144 (50.69%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH--SCN--SKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMIS 490
            MV F C +C  S++  QV  H  +C      SC+ C M+F  Q+ K+H++CISE EKY G  F A    +K   K+  W   + + +N+   +   ++ ++ SI    N+P K+  F N++K+ L    ++       +W + S
Sbjct:    1 MVFFTCDACGESVKKAQVEKHLNACRNCQCLSCIDCGMDFRGQDYKTHLRCISENEKYGGKGFEAK--ASKGDVKQQLWLQKVQDAINAPGIS-PQVRDIMNSIVGYDNVPRKKPKFQNWMKNSL---RVHKQELLDRVWEVFS 138
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Nematostella
Match: EDO48698 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIF9])

HSP 1 Score: 69.3218 bits (168), Expect = 7.741e-13
Identity = 42/127 (33.07%), Postives = 63/127 (49.61%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVH------SCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKL 433
            MV F+C++C  S+R NQV  H      +C    SC+ C  +F       H  CI+EAEKY+G  F     +NK  +K+  W   + E  +  E  D  ++  +  +K   NIP K+  F NF K+ +
Sbjct:    1 MVSFICNACGQSIRKNQVEKHYQTVCRNCEV-LSCIDCGKDFHGDGYAGHTSCITEAEKYQGKLFKPKDKQNKGEQKQQQWIKQVQE-ASRAEDEDPQIKGPLRRLKQYSNIPRKKAKFQNFCKNSI 125
[Close]
BLAST of zf-LYAR domain-containing protein vs. Ensembl Medaka
Match: LYAR (Ly1 antibody reactive [Source:NCBI gene;Acc:101172807])

HSP 1 Score: 73.9442 bits (180), Expect = 1.154e-13
Identity = 65/220 (29.55%), Postives = 102/220 (46.36%), Query Frame = 2 
Query:   26 FLCLNNCLFQSLFKIMVVFVCSSCNSSLRINQVAVH-----SCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKKIKKDTELPETKKKSTRSDNKLKA 670
            FL     L+  L K MV F C++C  SL+  QV  H      C    SC+ C  +F   + K+H KCISE +KY G  F A    NK   K+  W   I+E LN   +    L+ V+  +    N+P K+  F N++K+ L  S   + +  + +W +I+   D    P    ++ +  AE Q      Q     + +KK+ ++ + ++K  R  N  KA
Sbjct:   41 FLKERLLLWIKLIK-MVFFTCNACGESLKKAQVDKHVNICRGCQV-LSCIDCGKDFWDDDYKNHTKCISEDQKYGGKGFEAK--ANKGDVKQQQWLQRIHEALNK-SSISPKLRDVLRQVSAYDNVPRKKAKFQNWMKNSLKIS---NTSLHEEVWNIIAAAVDV---PEDTQQHMEKEAEVQANTNGTQTPFGHEDVKKNKKMNKRERKEARQQNNGKA 249
[Close]
BLAST of zf-LYAR domain-containing protein vs. Planmine SMEST
Match: SMESG000081140.1 (SMESG000081140.1)

HSP 1 Score: 453.751 bits (1166), Expect = 1.375e-153
Identity = 249/249 (100.00%), Postives = 249/249 (100.00%), Query Frame = 2 
Query:   71 MVVFVCSSCNSSLRINQVAVHSCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASXXXXXXXXXXXXWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKKIKKDTELPETKKKSTRSDNKLKAENNNKIETCLPXXXXXXXXXXNLITDVATESPVEETSLEIKKQTKSNTN 817
            MVVFVCSSCNSSLRINQVAVHSCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASKNENKNIEKRNNWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKKIKKDTELPETKKKSTRSDNKLKAENNNKIETCLPKEKKFKKTKKNLITDVATESPVEETSLEIKKQTKSNTN
Sbjct:    1 MVVFVCSSCNSSLRINQVAVHSCNSKFSCLSCNMEFSQQNVKSHVKCISEAEKYKGIDFNASKNENKNIEKRNNWCNTINEFLNSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAKVIWTMISPLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKKIKKDTELPETKKKSTRSDNKLKAENNNKIETCLPKEKKFKKTKKNLITDVATESPVEETSLEIKKQTKSNTN 249

HSP 2 Score: 219.55 bits (558), Expect = 1.456e-63
Identity = 179/179 (100.00%), Postives = 179/179 (100.00%), Query Frame = 3 
Query: 1200 SRQIKSKPEKNKKLEIVKESSEEIGTKVDNERKTPEADAVVLTVXXXXXXXXXXXXXXXXXXVDEKIPSDDKPRVTENMMTNDGINNDKENVAVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQVAESGDNSKEIEQVVLTEKSGEENSMKRKGKKINKDVQAETKEENNTAE 1736
            SRQIKSKPEKNKKLEIVKESSEEIGTKVDNERKTPEADAVVLTVKGKEKKTKKNKNPEEKIKVDEKIPSDDKPRVTENMMTNDGINNDKENVAVKKKLKSKTKSKKLNVIEESKEEVEEIPKKPKKNKKQVAESGDNSKEIEQVVLTEKSGEENSMKRKGKKINKDVQAETKEENNTAE
Sbjct:  377 SRQIKSKPEKNKKLEIVKESSEEIGTKVDNERKTPEADAVVLTVKGKEKKTKKNKNPEEKIKVDEKIPSDDKPRVTENMMTNDGINNDKENVAVKKKLKSKTKSKKLNVIEESKEEVEEIPKKPKKNKKQVAESGDNSKEIEQVVLTEKSGEENSMKRKGKKINKDVQAETKEENNTAE 555
The following BLAST results are available for this feature:
BLAST of zf-LYAR domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
LYAR8.058e-929.60Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC... [more]
LYAR8.058e-929.60Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC... [more]
LYAR8.486e-640.00Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C16C10.84.779e-1533.33pep chromosome:WBcel235:III:4161951:4164171:-1 gen... [more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG129091.895e-1130.57gene:FBgn0033507 transcript:FBtr0088348[more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
kctd57.336e-1132.00potassium channel tetramerization domain containin... [more]
kctd58.507e-1132.00potassium channel tetramerization domain containin... [more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lyar2.450e-1330.56Ly1 antibody reactive clone [Source:MGI Symbol;Acc... [more]
Lyar2.879e-1330.56Ly1 antibody reactive clone [Source:MGI Symbol;Acc... [more]
Lyar4.261e-1330.56Ly1 antibody reactive clone [Source:MGI Symbol;Acc... [more]
Lyar4.261e-1330.56Ly1 antibody reactive clone [Source:MGI Symbol;Acc... [more]
Lyar4.661e-1232.80Ly1 antibody reactive clone [Source:MGI Symbol;Acc... [more]
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BLAST of zf-LYAR domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q09464|YQ58_CAEEL6.080e-1433.33Uncharacterized protein C16C10.8 OS=Caenorhabditis... [more]
sp|Q08288|LYAR_MOUSE2.981e-1230.56Cell growth-regulating nucleolar protein OS=Mus mu... [more]
sp|Q6AYK5|LYAR_RAT7.821e-1028.97Cell growth-regulating nucleolar protein OS=Rattus... [more]
sp|Q9NX58|LYAR_HUMAN4.191e-829.60Cell growth-regulating nucleolar protein OS=Homo s... [more]
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BLAST of zf-LYAR domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
L7MKM72.676e-1533.12Putative cell growth-regulating nucleolar protein ... [more]
A0A0N8BIM43.415e-1533.69Cell growth-regulating nucleolar protein OS=Daphni... [more]
L7M4C74.414e-1533.12Putative cell growth-regulating nucleolar protein ... [more]
A0A131XFB04.622e-1533.12Putative cell growth-regulating nucleolar protein ... [more]
A0A0L8IAX64.727e-1534.11zf-LYAR domain-containing protein OS=Octopus bimac... [more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
lyar3.199e-1232.45Ly1 antibody reactive homolog (mouse) [Source:ZFIN... [more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
LYAR2.789e-1329.86Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO486987.741e-1333.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of zf-LYAR domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
LYAR1.154e-1329.55Ly1 antibody reactive [Source:NCBI gene;Acc:101172... [more]
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BLAST of zf-LYAR domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000081140.11.375e-153100.00SMESG000081140.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031929 ID=SMED30031929|Name=zf-LYAR domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1818bp
TTTAAATTAGCCAAAAACTATGAAATTCCTTTGTTTAAATAATTGTTTAT
TTCAAAGTCTCTTTAAAATCATGGTTGTTTTTGTATGCTCATCTTGCAAT
TCTTCGTTAAGAATAAACCAAGTTGCTGTCCATTCTTGTAATTCAAAATT
TTCTTGTCTTTCATGTAATATGGAATTTAGCCAGCAAAACGTAAAAAGTC
ATGTTAAATGTATTTCAGAAGCAGAGAAGTATAAAGGCATTGATTTCAAT
GCAAGTAAAAATGAAAATAAAAACATTGAAAAGAGAAATAACTGGTGTAA
TACAATAAATGAATTTTTAAATTCATATGAAACCACTGATAGTAACTTGC
AAAAAGTCATAGCTTCAATTAAAAACCAACCAAATATTCCTGATAAGGAA
AAGCCATTTTGTAATTTTGTTAAAAGTAAATTGGGTTATTCTGTTCTTAA
TTCAAACAATTATGCAAAAGTTATTTGGACAATGATTTCCCCCCTTAAAG
ATGCTTTAAAGAAACCAATTTCCATCACTAAAAATAATCAAGTTAACGCG
GAAGCACAAAAACGTAAACTTGAAGAACAAGAAGAATCCGTCACGAAAAA
GATCAAAAAAGACACAGAGTTACCTGAAACTAAAAAGAAGTCTACAAGAT
CTGACAACAAACTAAAAGCAGAAAATAACAACAAAATTGAAACTTGTTTA
CCTAAAGAAAAGAAATTTAAAAAAACCAAAAAAAATTTAATTACCGATGT
TGCTACAGAAAGCCCAGTAGAGGAAACTAGCCTAGAAATTAAGAAACAAA
CAAAATCAAACACTAATAAAGATAAGAAACCGGAAATAGTTGAAGAAAAA
GTAGAAAAGGTTAAACCAATCAAAAAGAAAAATAAAAAAATTGATACCGA
AACTGCTGAGGAAAATGAAAAGGAAATAAATGAATCCAAAGAAAAAAAAA
TCAAAGCCCGAGAAAAACACGGAACCAGAAATTAAAGGTGAAGTTGAAAA
GCAATCAAAGATAAAATCCAAAAAAAACAAAAAGCCAGAAATAATCGAAG
AAAAGATTGGAGAAGAAAATAAAAAGAAAACTAAAAAAAGTGACAAAAAT
AAAGGGGAAATTAAAGAAAAAGTTGCAGTAGAAAAACCGAAAGAAAAGAA
AATCAAAACCAACAAAGTTGAAACTATGGAAACTGAAACTAAAGTTGAAA
GTCGACAAATAAAGTCAAAACCCGAGAAAAATAAGAAATTGGAAATAGTG
AAGGAAAGCTCGGAAGAAATCGGAACTAAAGTAGATAACGAGAGGAAAAC
TCCGGAAGCCGACGCAGTGGTTTTGACAGTTAAAGGAAAAGAAAAGAAAA
CCAAAAAGAATAAAAATCCCGAAGAAAAGATAAAAGTCGATGAGAAAATT
CCATCTGATGATAAACCGAGAGTGACTGAAAATATGATGACAAATGATGG
AATCAATAATGACAAAGAAAATGTTGCAGTTAAAAAGAAGTTAAAATCAA
AGACTAAAAGCAAGAAACTCAATGTAATTGAAGAATCAAAAGAGGAAGTT
GAAGAAATCCCGAAGAAACCAAAAAAAAATAAAAAGCAGGTCGCGGAATC
GGGAGATAATTCCAAGGAAATTGAGCAGGTGGTATTGACGGAAAAGTCTG
GCGAGGAAAATTCTATGAAAAGGAAAGGGAAAAAAATCAATAAAGATGTT
CAAGCTGAAACTAAAGAAGAAAACAATACTGCTGAAAAACAAAGAAAAAA
GAGAAAACTGAACTAGAGAAATAAATGTTAAATGTTTCGCATTTTGATAA
TAAAATTATATTCTATTT
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protein sequence of SMED30031929-orf-1

>SMED30031929-orf-1 ID=SMED30031929-orf-1|Name=SMED30031929-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=279bp
MNPKKKKSKPEKNTEPEIKGEVEKQSKIKSKKNKKPEIIEEKIGEENKKK
TKKSDKNKGEIKEKVAVEKPKEKKIKTNKVETMETETKVESRQIKSKPEK
NKKLEIVKESSEEIGTKVDNERKTPEADAVVLTVKGKEKKTKKNKNPEEK
IKVDEKIPSDDKPRVTENMMTNDGINNDKENVAVKKKLKSKTKSKKLNVI
EESKEEVEEIPKKPKKNKKQVAESGDNSKEIEQVVLTEKSGEENSMKRKG
KKINKDVQAETKEENNTAEKQRKKRKLN*
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protein sequence of SMED30031929-orf-2

>SMED30031929-orf-2 ID=SMED30031929-orf-2|Name=SMED30031929-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=322bp
MKFLCLNNCLFQSLFKIMVVFVCSSCNSSLRINQVAVHSCNSKFSCLSCN
MEFSQQNVKSHVKCISEAEKYKGIDFNASKNENKNIEKRNNWCNTINEFL
NSYETTDSNLQKVIASIKNQPNIPDKEKPFCNFVKSKLGYSVLNSNNYAK
VIWTMISPLKDALKKPISITKNNQVNAEAQKRKLEEQEESVTKKIKKDTE
LPETKKKSTRSDNKLKAENNNKIETCLPKEKKFKKTKKNLITDVATESPV
EETSLEIKKQTKSNTNKDKKPEIVEEKVEKVKPIKKKNKKIDTETAEENE
KEINESKEKKIKAREKHGTRN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003723RNA binding
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR039999LYAR
IPR036236Znf_C2H2_sf
IPR014898Znf_C2H2_LYAR
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005730nucleolus
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 167..197
NoneNo IPR availableGENE3DG3DSA:2.20.28.110coord: 18..64
e-value: 4.4E-8
score: 35.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 252..321
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 180..223
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 247..321
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..24
score: 0.577
IPR014898Zinc finger, C2H2, LYAR-typePFAMPF08790zf-LYARcoord: 44..71
e-value: 5.4E-11
score: 42.2
IPR039999Cell growth-regulating nucleolar proteinPANTHERPTHR13100FAMILY NOT NAMEDcoord: 18..313
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 43..71