PHB domain-containing protein

Overview


Name	PHB domain-containing protein
Smed ID	SMED30031859
Length (bp)	1127

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of PHB domain-containing protein (SMED30031859) t-SNE clustered cells

Violin plots show distribution of expression levels for PHB domain-containing protein (SMED30031859) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PHB domain-containing protein (SMED30031859) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PHB domain-containing protein (SMED30031859) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30031859

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30031859	SMESG000021969.1	dd_Smed_v4_14462_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30031859	SMESG000021969.1	dd_Smed_v4_14462_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30031859	SMESG000021969.1	dd_Smed_v4_14462_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30031859	SMESG000021969.1	dd_Smed_v4_14462_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of PHB domain-containing protein vs. Ensembl Human
Match: STOM (stomatin [Source:HGNC Symbol;Acc:HGNC:3383])

HSP 1 Score: 268.855 bits (686), Expect = 4.782e-88
Identity = 157/257 (61.09%), Postives = 205/257 (79.77%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIES 1112
            I+   +++  V+TFP S+ +CIKI++EYERA+IFRLGR+  GGAKGPG+FFILPC +++ KVD+RTISFD+PPQE+LT+DSVT+ VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNLS+ILS+RE I+  +Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEA+REARAK IA+EGE +AS ALKEAS ++ ES  A+QLRYLQTL  +A EK STI+FPLP+ +LQ +I +
Sbjct:   33 ILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQ-------STLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIIGA 282

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BLAST of PHB domain-containing protein vs. Ensembl Human
Match: STOML3 (stomatin like 3 [Source:HGNC Symbol;Acc:HGNC:19420])

HSP 1 Score: 253.832 bits (647), Expect = 3.915e-82
Identity = 154/275 (56.00%), Postives = 207/275 (75.27%), Query Frame = 3

Query:  279 EKKEFENIDDSSIHEQRGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQ 1097
            EK++ EN     ++ +R   C  I+  L++++V++TFP S+ +C+KI++EYERAV+FRLGR+    AKGPG+  +LPCI+ + KVDLRT++ ++PPQE+LTRDSVT +VD VV YRI +AV +VANV D HQ+T L+AQ+TLRNVLGT+ LS+IL+ RE I+ ++Q         L  AT  WGI++ RVEIKD R+P  LQRSMAAEAEA REARAK +A+EGE +AS +LK AS +L ES  A+QLRYLQTL  VA EK STI+FPLP+ +L+
Sbjct:    9 EKQDKENF--VGVNNKRLGVCGWILFSLSFLLVIITFPISIWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQT-------LLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQTLSTVATEKNSTIVFPLPMNILE 274

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Human
Match: STOML3 (stomatin like 3 [Source:HGNC Symbol;Acc:HGNC:19420])

HSP 1 Score: 251.521 bits (641), Expect = 2.796e-81
Identity = 150/264 (56.82%), Postives = 201/264 (76.14%), Query Frame = 3

Query:  312 SIHEQRGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQ 1097
             ++ +R   C  I+  L++++V++TFP S+ +C+KI++EYERAV+FRLGR+    AKGPG+  +LPCI+ + KVDLRT++ ++PPQE+LTRDSVT +VD VV YRI +AV +VANV D HQ+T L+AQ+TLRNVLGT+ LS+IL+ RE I+ ++Q         L  AT  WGI++ RVEIKD R+P  LQRSMAAEAEA REARAK +A+EGE +AS +LK AS +L ES  A+QLRYLQTL  VA EK STI+FPLP+ +L+
Sbjct:    9 GVNNKRLGVCGWILFSLSFLLVIITFPISIWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQ-------TLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQTLSTVATEKNSTIVFPLPMNILE 265

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Human
Match: STOM (stomatin [Source:HGNC Symbol;Acc:HGNC:3383])

HSP 1 Score: 186.037 bits (471), Expect = 1.966e-57
Identity = 80/127 (62.99%), Postives = 108/127 (85.04%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKN 722
            I+   +++  V+TFP S+ +CIKI++EYERA+IFRLGR+  GGAKGPG+FFILPC +++ KVD+RTISFD+PPQE+LT+DSVT+ VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKN
Sbjct:   33 ILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKN 159

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Human
Match: NPHS2 (NPHS2 stomatin family member, podocin [Source:HGNC Symbol;Acc:HGNC:13394])

HSP 1 Score: 186.422 bits (472), Expect = 7.344e-55
Identity = 113/259 (43.63%), Postives = 177/259 (68.34%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQ-----LTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYL 1103
            ++ +++ + +++TFPFS+  C+K+VQEYER +IFRLG L  G AKGPG+FF LPC++TY KVDLR  + ++P  E++T+D   +++DA+  YR+ NA + ++++    ++ + + Q+T++ +L  ++L+EIL E            RKS  Q     L S T  WGI++ER+EIKD RLP  LQ S+A EAEA R+A+ + IA+E EK+AS +L+ A++IL+ +  A+QLRYL TL +++ EK ST++ PLP  LL  L
Sbjct:  104 LLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEIVTKDMFIMEIDAICYYRMENASLLLSSLAHVSKAVQFLVQTTMKRLLAHRSLTEILLE------------RKSIAQDAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCL 350

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BLAST of PHB domain-containing protein vs. Ensembl Celegans
Match: sto-2 (Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q19958])

HSP 1 Score: 283.108 bits (723), Expect = 5.079e-93
Identity = 167/251 (66.53%), Postives = 209/251 (83.27%), Query Frame = 3

Query:  354 LAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            L++I+V+ TFP S+  C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+YTKVDLRT+SF VPPQE+LT+DSVT  VDAV+ YRI NA VSVANVE+AH STRL+AQ+TLRN+LGT++LSEILS+RE+++ ++Q         L  AT  WGI++ERVEIKD RLP  LQR+MAAEAEA REARAK IA+EGE+ AS AL++A+ ++ +S  A+QLRYLQTL +VA EK STIIFPLP+ L+++LI
Sbjct:  114 LSWIMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVDLRTVSFSVPPQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNMLGTRSLSEILSDRETLAASMQT-------ILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATREARAKVIAAEGEQKASRALRDAASVIAQSPAALQLRYLQTLNSVAAEKNSTIIFPLPMELVRHLI 357

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Celegans
Match: mec-2 (Mechanosensory protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q27433])

HSP 1 Score: 283.493 bits (724), Expect = 8.621e-93
Identity = 180/334 (53.89%), Postives = 242/334 (72.46%), Query Frame = 3

Query:  126 SKNSEQQRFYSCNSDQ-ENNQSRFYEDFEFNEINNYEISSFIEKPEIKFDHVEKKEFENIDD----SSIHEQRGVTC-IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            S +S+     S +SD+ EN  +R  +  E +      IS+  +   +K +   +K+ E  +     ++I  + GV   I+TIL+Y+++  T P S  +CIK+VQEYERAVIFRLGRL  GGAKGPGIFFI+PCI+TY KVDLR +SF+VPPQE+L++DSVTV VDAVV +RI NA +SV NVEDA +ST+L+AQ+TLRN+LGTK L+E+LS+RE+IS  +Q         L  AT PWG+++ERVE+KD RLP  LQR+MAAEAEAAREARAK I +EGE+ AS ALKEA++++ ES +A+QLRYLQTL +++ EK STIIFP P+ LL   ++
Sbjct:   45 SSSSKDDDLLSTSSDEVENMATRTLQQLEES---TSIISANSDDDSVKKEKQAEKDVEKGNGKEEKANIQNEFGVCGWILTILSYLLIFFTLPISACMCIKVVQEYERAVIFRLGRLMPGGAKGPGIFFIVPCIDTYRKVDLRVLSFEVPPQEILSKDSVTVAVDAVVYFRISNATISVTNVEDAARSTKLLAQTTLRNILGTKTLAEMLSDREAISHQMQTT-------LDEATEPWGVKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIVAEGEQKASRALKEAAEVIAESPSALQLRYLQTLNSISAEKNSTIIFPFPIDLLSAFLQ 368

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Celegans
Match: sto-2 (Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q19958])

HSP 1 Score: 280.796 bits (717), Expect = 9.520e-93
Identity = 167/251 (66.53%), Postives = 209/251 (83.27%), Query Frame = 3

Query:  354 LAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            L++I+V+ TFP S+  C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+YTKVDLRT+SF VPPQE+LT+DSVT  VDAV+ YRI NA VSVANVE+AH STRL+AQ+TLRN+LGT++LSEILS+RE+++ ++Q         L  AT  WGI++ERVEIKD RLP  LQR+MAAEAEA REARAK IA+EGE+ AS AL++A+ ++ +S  A+QLRYLQTL +VA EK STIIFPLP+ L+++LI
Sbjct:   76 LSWIMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVDLRTVSFSVPPQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNMLGTRSLSEILSDRETLAASMQT-------ILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATREARAKVIAAEGEQKASRALRDAASVIAQSPAALQLRYLQTLNSVAAEKNSTIIFPLPMELVRHLI 319

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Celegans
Match: sto-2 (Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q19958])

HSP 1 Score: 281.952 bits (720), Expect = 1.029e-92
Identity = 167/251 (66.53%), Postives = 209/251 (83.27%), Query Frame = 3

Query:  354 LAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            L++I+V+ TFP S+  C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+YTKVDLRT+SF VPPQE+LT+DSVT  VDAV+ YRI NA VSVANVE+AH STRL+AQ+TLRN+LGT++LSEILS+RE+++ ++Q         L  AT  WGI++ERVEIKD RLP  LQR+MAAEAEA REARAK IA+EGE+ AS AL++A+ ++ +S  A+QLRYLQTL +VA EK STIIFPLP+ L+++LI
Sbjct:  103 LSWIMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVDLRTVSFSVPPQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNMLGTRSLSEILSDRETLAASMQT-------ILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATREARAKVIAAEGEQKASRALRDAASVIAQSPAALQLRYLQTLNSVAAEKNSTIIFPLPMELVRHLI 346

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Celegans
Match: sto-2 (Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q19958])

HSP 1 Score: 282.337 bits (721), Expect = 1.496e-92
Identity = 167/251 (66.53%), Postives = 209/251 (83.27%), Query Frame = 3

Query:  354 LAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            L++I+V+ TFP S+  C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+YTKVDLRT+SF VPPQE+LT+DSVT  VDAV+ YRI NA VSVANVE+AH STRL+AQ+TLRN+LGT++LSEILS+RE+++ ++Q         L  AT  WGI++ERVEIKD RLP  LQR+MAAEAEA REARAK IA+EGE+ AS AL++A+ ++ +S  A+QLRYLQTL +VA EK STIIFPLP+ L+++LI
Sbjct:  131 LSWIMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVDLRTVSFSVPPQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNMLGTRSLSEILSDRETLAASMQT-------ILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATREARAKVIAAEGEQKASRALRDAASVIAQSPAALQLRYLQTLNSVAAEKNSTIIFPLPMELVRHLI 374

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Fly
Match: CG42540 (gene:FBgn0260657 transcript:FBtr0301096)

HSP 1 Score: 288.886 bits (738), Expect = 1.160e-94
Identity = 169/265 (63.77%), Postives = 213/265 (80.38%), Query Frame = 3

Query:  327 RGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            +  TC  ++  L+  +V++T PFSL +C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI++Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS  +QV       QL  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ L+ Y +++N
Sbjct:   63 KASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQV-------QLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFLKTN 320

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Fly
Match: CG42540 (gene:FBgn0260657 transcript:FBtr0344807)

HSP 1 Score: 288.886 bits (738), Expect = 1.316e-94
Identity = 169/265 (63.77%), Postives = 213/265 (80.38%), Query Frame = 3

Query:  327 RGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            +  TC  ++  L+  +V++T PFSL +C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI++Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS  +QV       QL  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ L+ Y +++N
Sbjct:   70 KASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQV-------QLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFLKTN 327

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Fly
Match: CG42540 (gene:FBgn0260657 transcript:FBtr0333583)

HSP 1 Score: 288.5 bits (737), Expect = 1.320e-94
Identity = 169/265 (63.77%), Postives = 213/265 (80.38%), Query Frame = 3

Query:  327 RGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            +  TC  ++  L+  +V++T PFSL +C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI++Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS  +QV       QL  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ L+ Y +++N
Sbjct:   58 KASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQV-------QLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFLKTN 315

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BLAST of PHB domain-containing protein vs. Ensembl Fly
Match: CG42540 (gene:FBgn0260657 transcript:FBtr0333584)

HSP 1 Score: 288.886 bits (738), Expect = 1.766e-94
Identity = 169/265 (63.77%), Postives = 213/265 (80.38%), Query Frame = 3

Query:  327 RGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            +  TC  ++  L+  +V++T PFSL +C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI++Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS  +QV       QL  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ L+ Y +++N
Sbjct:   74 KASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQV-------QLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFLKTN 331

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BLAST of PHB domain-containing protein vs. Ensembl Fly
Match: CG42540 (gene:FBgn0260657 transcript:FBtr0301097)

HSP 1 Score: 288.115 bits (736), Expect = 1.913e-94
Identity = 169/265 (63.77%), Postives = 213/265 (80.38%), Query Frame = 3

Query:  327 RGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            +  TC  ++  L+  +V++T PFSL +C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI++Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS  +QV       QL  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ L+ Y +++N
Sbjct:   62 KASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQV-------QLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFLKTN 319

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BLAST of PHB domain-containing protein vs. Ensembl Zebrafish
Match: stoml3b (stomatin (EPB72)-like 3b [Source:ZFIN;Acc:ZDB-GENE-050417-366])

HSP 1 Score: 258.84 bits (660), Expect = 2.294e-84
Identity = 158/255 (61.96%), Postives = 202/255 (79.22%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            I+ I++    +L FP S+ I IKIV+EYERAVIFRLGR+T   AKGPGIFFI+PC +++ KVDLRT+SFD+PPQE+LT+DSVTV VD VV +R+ + V SVANV +A  STRL+AQ+TLRNVLGTKNL+E+LS+RE IS ++Q         L  AT  WGI++ERVEIKD +LP+ LQR+MAAEAEA+REARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK STI+FPLP+ ++ + I
Sbjct:   31 ILVIISAFFSILVFPISIFISIKIVKEYERAVIFRLGRITARKAKGPGIFFIIPCTDSFIKVDLRTVSFDIPPQEILTKDSVTVSVDGVVYFRVNDPVASVANVSNADYSTRLLAQTTLRNVLGTKNLAEVLSDREGISHSMQTT-------LDEATDSWGIKVERVEIKDVKLPQQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIVFPLPIDIMNHFI 278

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BLAST of PHB domain-containing protein vs. Ensembl Zebrafish
Match: zgc:112408 (zgc:112408 [Source:ZFIN;Acc:ZDB-GENE-050417-63])

HSP 1 Score: 256.914 bits (655), Expect = 1.678e-83
Identity = 146/251 (58.17%), Postives = 201/251 (80.08%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLL 1094
            I+T  + +++  TFP S+  C+K+VQEYERAVIFRLGRL  GGAKGPG+F+I+PC++T+ KVDLRT+SFD+P QEVLT+DSVT+ VDAVV YRI N  VS+  VE+A+ +T+++AQ+TLRN+LGTK+L++IL +RE +S  ++         L SA+  WGI++ERVE+KD +LP  LQR+MAAEAEA+R+ARAK IA+EGE  AS ALKEA+ +++ES  A+QLRY+QTL  +A+E+ STIIFP+P+ L+
Sbjct:   43 ILTFFSCLLIFFTFPVSVWFCMKVVQEYERAVIFRLGRL-LGGAKGPGLFWIIPCMDTFRKVDLRTVSFDIPAQEVLTKDSVTIMVDAVVYYRIFNPTVSITKVENANYATQMLAQTTLRNMLGTKSLADILKDREEMSEQMEA-------VLYSASKNWGIKVERVELKDVKLPTTLQRAMAAEAEASRDARAKVIAAEGEMKASRALKEAANVMSESPAALQLRYMQTLTEIASERNSTIIFPVPMDLM 285

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BLAST of PHB domain-containing protein vs. Ensembl Zebrafish
Match: zgc:112408 (zgc:112408 [Source:ZFIN;Acc:ZDB-GENE-050417-63])

HSP 1 Score: 256.914 bits (655), Expect = 2.227e-83
Identity = 146/251 (58.17%), Postives = 201/251 (80.08%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLL 1094
            I+T  + +++  TFP S+  C+K+VQEYERAVIFRLGRL  GGAKGPG+F+I+PC++T+ KVDLRT+SFD+P QEVLT+DSVT+ VDAVV YRI N  VS+  VE+A+ +T+++AQ+TLRN+LGTK+L++IL +RE +S  ++         L SA+  WGI++ERVE+KD +LP  LQR+MAAEAEA+R+ARAK IA+EGE  AS ALKEA+ +++ES  A+QLRY+QTL  +A+E+ STIIFP+P+ L+
Sbjct:   56 ILTFFSCLLIFFTFPVSVWFCMKVVQEYERAVIFRLGRL-LGGAKGPGLFWIIPCMDTFRKVDLRTVSFDIPAQEVLTKDSVTIMVDAVVYYRIFNPTVSITKVENANYATQMLAQTTLRNMLGTKSLADILKDREEMSEQMEA-------VLYSASKNWGIKVERVELKDVKLPTTLQRAMAAEAEASRDARAKVIAAEGEMKASRALKEAANVMSESPAALQLRYMQTLTEIASERNSTIIFPVPMDLM 298

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BLAST of PHB domain-containing protein vs. Ensembl Zebrafish
Match: stom (stomatin [Source:ZFIN;Acc:ZDB-GENE-980526-486])

HSP 1 Score: 254.603 bits (649), Expect = 1.577e-82
Identity = 155/262 (59.16%), Postives = 203/262 (77.48%), Query Frame = 3

Query:  345 ITILAYIVVVLTFPF-------SLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            I +  +I+V+ +          S+ +CIKIV+EYERA+IFRLGR+  GGAKGPG+FFILPC +++  VD+RTI+FD+PPQEVLT+DSVTV VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNL+EILS+RE I+ ++Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEA+REARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK STIIFPLP+ ++Q  ++
Sbjct:   39 IGLCGWILVIFSILLTLLTLPLSIWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFILPCTDSFINVDMRTITFDIPPQEVLTKDSVTVSVDGVVYYRVQNATLAVANITNADAATRLLAQTTLRNVLGTKNLAEILSDREEIAHSMQ-------STLDDATDDWGIKVERVEIKDVKLPLQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIIFPLPIDMMQSFLK 293

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Query:  345 ITILAYIVVVLTFPF-------SLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            I +  +I+V+ +          S+ +CIKIV+EYERA+IFRLGR+  GGAKGPG+FFILPC +++  VD+RTI+FD+PPQEVLT+DSVTV VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNL+EILS+RE I+ ++Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEA+REARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK STIIFPLP+ ++Q  ++
Sbjct:   39 IGLCGWILVIFSILLTLLTLPLSIWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFILPCTDSFINVDMRTITFDIPPQEVLTKDSVTVSVDGVVYYRVQNATLAVANITNADAATRLLAQTTLRNVLGTKNLAEILSDREEIAHSMQ-------STLDDATDDWGIKVERVEIKDVKLPLQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIIFPLPIDMMQSFLK 293

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BLAST of PHB domain-containing protein vs. Ensembl Xenopus
Match: myo10.2 (myosin 10, gene 2 [Source:Xenbase;Acc:XB-GENE-5995373])

HSP 1 Score: 268.47 bits (685), Expect = 9.737e-88
Identity = 166/291 (57.04%), Postives = 221/291 (75.95%), Query Frame = 3

Query:  246 IEKPEIKFDHVEKKEFENIDDSSIHEQRGVTC---IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            +  PE+K     +++  NI++S      G+ C    + IL++   +LTFP S+ +CIKIV+EYERA+IFRLGR+  GGAKGPG+FF+LPC +++  VD+RTISFD+PPQE+LT+DSVTV VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNLS+ILS+RE I+  +Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS +++ES  A+QLRYLQTL  +A+EK STI+FPLP+ LL+  ++
Sbjct:   24 MADPELKSRRANQED-RNIEES----DGGLGCCGWFLVILSFFFTLLTFPISVWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFVLPCTDSFINVDMRTISFDIPPQEILTKDSVTVSVDGVVYYRVNNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQ-------STLDVATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASIVISESPAALQLRYLQTLTTIASEKNSTIVFPLPLDLLKGFMQ 302

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Xenopus
Match: myo10.2 (myosin 10, gene 2 [Source:Xenbase;Acc:XB-GENE-5995373])

HSP 1 Score: 264.618 bits (675), Expect = 9.338e-87
Identity = 160/263 (60.84%), Postives = 208/263 (79.09%), Query Frame = 3

Query:  330 GVTC---IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            G+ C    + IL++   +LTFP S+ +CIKIV+EYERA+IFRLGR+  GGAKGPG+FF+LPC +++  VD+RTISFD+PPQE+LT+DSVTV VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNLS+ILS+RE I+  +Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS +++ES  A+QLRYLQTL  +A+EK STI+FPLP+ LL+  ++
Sbjct:    8 GLGCCGWFLVILSFFFTLLTFPISVWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFVLPCTDSFINVDMRTISFDIPPQEILTKDSVTVSVDGVVYYRVNNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQ-------STLDVATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASIVISESPAALQLRYLQTLTTIASEKNSTIVFPLPLDLLKGFMQ 263

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Xenopus
Match: myo10.2 (myosin 10, gene 2 [Source:Xenbase;Acc:XB-GENE-5995373])

HSP 1 Score: 263.462 bits (672), Expect = 3.591e-86
Identity = 158/255 (61.96%), Postives = 205/255 (80.39%), Query Frame = 3

Query:  345 ITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            + IL++   +LTFP S+ +CIKIV+EYERA+IFRLGR+  GGAKGPG+FF+LPC +++  VD+RTISFD+PPQE+LT+DSVTV VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNLS+ILS+RE I+  +Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS +++ES  A+QLRYLQTL  +A+EK STI+FPLP+ LL+  ++
Sbjct:   23 LVILSFFFTLLTFPISVWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFVLPCTDSFINVDMRTISFDIPPQEILTKDSVTVSVDGVVYYRVNNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQ-------STLDVATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASIVISESPAALQLRYLQTLTTIASEKNSTIVFPLPLDLLKGFMQ 270

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BLAST of PHB domain-containing protein vs. Ensembl Xenopus
Match: atp8b3 (ATPase, aminophospholipid transporter, class I, type 8B, member 3 [Source:Xenbase;Acc:XB-GENE-992174])

HSP 1 Score: 241.121 bits (614), Expect = 2.565e-77
Identity = 143/252 (56.75%), Postives = 191/252 (75.79%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQ 1097
            II IL+  +  +TFP S+  C+KI+QEYERAV+FRLGR+  G AKGPG+ F+LPC +T+ KVDLR ISF +PPQE+LT+DSVT  VD VV Y I +A+ +VANV + H +T+ +AQ+TLRN+LGT+ L+ IL+ RE I+  +Q         L  AT+ WG++++RVE++D RLP  +QR+MAAEAEAAREARAK +A+EGE +AS ALKEAS ++ ES  A+QLRYLQTL  +A E  STI+FPLP+ L+Q
Sbjct:   33 IILILSAFMAAITFPLSIWFCVKIIQEYERAVVFRLGRIISGKAKGPGVMFVLPCTDTFIKVDLRVISFAIPPQEILTKDSVTTTVDGVVYYNIQSAIKAVANVNNVHIATQQLAQTTLRNILGTQTLANILANREEIAHNIQ-------SILDHATHKWGVKVDRVEMRDVRLPVQMQRAMAAEAEAAREARAKVVAAEGEMNASRALKEASLVIAESPAALQLRYLQTLNTIAAENNSTIVFPLPIELMQ 277

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BLAST of PHB domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046764.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:2:22368844:22379341:1 gene:ENSXETG00000020360.1 transcript:ENSXETT00000046764.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 201.06 bits (510), Expect = 1.024e-62
Identity = 116/216 (53.70%), Postives = 164/216 (75.93%), Query Frame = 3

Query:  468 GAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTS----ATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYL 1103
            GAKGPG+F++LPC +    VD+RT+SF VPPQEVLT+DSVT+ VDAVV YR+ N  V+V  V++A Q+T+++AQ+TLRN+LGTK+L++           + V   +  EQ++     AT  WGI++ERVEIKD +LP+ LQR+MAAEAEA+R+ARAK IA+EGE +AS +LKEA+ I++E+  A+QLRYLQTL +++ EK STI+FP+P+ ++  L
Sbjct:    2 GAKGPGVFWVLPCADNIKIVDIRTVSFAVPPQEVLTKDSVTIMVDAVVFYRVFNPTVAVVKVDNASQATQMLAQTTLRNMLGTKSLTQ-----------ILVEREEMAEQMSKILYEATRDWGIRVERVEIKDVKLPQSLQRAMAAEAEASRDARAKVIAAEGEMNASRSLKEAALIMSETPAALQLRYLQTLSHISAEKNSTIVFPVPMDIISML 206

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BLAST of PHB domain-containing protein vs. Ensembl Mouse
Match: Stom (stomatin [Source:MGI Symbol;Acc:MGI:95403])

HSP 1 Score: 271.166 bits (692), Expect = 3.667e-89
Identity = 166/282 (58.87%), Postives = 213/282 (75.53%), Query Frame = 3

Query:  273 HVEKKEF-ENIDDSSIHEQRGVTCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            HV+ +   E+  ++S  E      I+   ++  V++TFP S+ ICIKIV+EYER +IFRLGR+  GGAKGPG+FFILPC ++  KVD+RTISFD+PPQEVLT+DSVT+ VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRN LGTKNLS+ILS+RE I+  +Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS ++ ES  A+QLRYLQTL  +A EK STI+FPLPV +LQ ++ SN
Sbjct:    9 HVQSQRIPESFRENSKTELGACGWILVAASFFFVIITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILPCTDSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQ-------STLDDATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPVDMLQGIMGSN 283

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BLAST of PHB domain-containing protein vs. Ensembl Mouse
Match: Stoml3 (stomatin (Epb7.2)-like 3 [Source:MGI Symbol;Acc:MGI:2388072])

HSP 1 Score: 245.743 bits (626), Expect = 3.496e-79
Identity = 146/241 (60.58%), Postives = 187/241 (77.59%), Query Frame = 3

Query:  375 LTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQ 1097
            +TFP S+ +C+KI++EYERAV+FRLGR+    AKGPG+  +LPCI+ + KVDLRT++ ++PPQE+LTRDSVT +VD VV YRI +AV +VANV D HQ+T L+AQ+TLRNVLGT+ LS+ILS RE I+ ++Q         L  AT  WGI++ RVEIKD R+P  LQRSMAAEAEA REARAK +A+EGE +AS +LK AS +L ES  A+QLRYLQTL  VA EK STI+FPLP+ +L+
Sbjct:   37 VTFPISVWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILSGREEIAHSIQT-------LLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLKSASMVLAESPVALQLRYLQTLTTVATEKNSTIVFPLPMNILE 270

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Mouse
Match: Nphs2 (nephrosis 2, podocin [Source:MGI Symbol;Acc:MGI:2157018])

HSP 1 Score: 197.978 bits (502), Expect = 2.244e-59
Identity = 116/254 (45.67%), Postives = 180/254 (70.87%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYL 1103
            ++ + + I +++TFPFS+  CIK+VQEYER +IFRLG L  G AKGPG+FF LPC++TY KVDLR  + ++P  EV+T+D   +++DAV  YR+ NA + ++++    ++ + + Q+T++ +L  ++L+EIL ER+SI+  V+V        L + T  WGI++ER EIKD RLP  LQ S+A EAEA R+A+ + IA+EGEK+AS +L+ A++IL+ +  A+QLRYL TL +++ EK +T++ PLP  +L  L
Sbjct:  106 LLVLASLIFIIMTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASLLLSSLAHVSKAIQFLVQTTMKRLLAHRSLTEILLERKSIAQDVKV-------ALDAVTCIWGIKVERTEIKDVRLPAGLQHSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPATVVLPLPFDMLSLL 352

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Mouse
Match: Nphs2 (nephrosis 2, podocin [Source:MGI Symbol;Acc:MGI:2157018])

HSP 1 Score: 147.902 bits (372), Expect = 1.112e-41
Identity = 90/255 (35.29%), Postives = 143/255 (56.08%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEI-KDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYL 1103
            ++ + + I +++TFPFS+  CIK+VQEYER +IFRLG L  G AKGPG+FF LPC++TY KVDLR  + ++P  EV+T+D   +++DAV  YR+ NA + ++++  AH S                              A+Q   + + ++L +      I +ER  I +D ++                      IA+EGEK+AS +L+ A++IL+ +  A+QLRYL TL +++ EK +T++ PLP  +L  L
Sbjct:   31 LLVLASLIFIIMTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASLLLSSL--AHVSK-----------------------------AIQFLVQTTMKRLLAHRSLTEILLERKSIAQDVKV----------------------IAAEGEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPATVVLPLPFDMLSLL 232

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BLAST of PHB domain-containing protein vs. Ensembl Mouse
Match: Stoml1 (stomatin-like 1 [Source:MGI Symbol;Acc:MGI:1916356])

HSP 1 Score: 100.523 bits (249), Expect = 5.027e-23
Identity = 57/161 (35.40%), Postives = 93/161 (57.76%), Query Frame = 3

Query:  378 TFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQL----TSATYPWGIQMERVEI 848
            TFP S    +KIV  YER ++FRLGR+     +GPG+  +LP I+++ +VDLRT +F+VPP ++ ++D   + V A V +RI + V+SV  V+D + +TR+ A + +   L  + L E           +Q+   K  +QL       T  WG++++RVE+
Sbjct:   70 TFPISGWFALKIVPTYERMIVFRLGRIRN--PQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMAVKDLNTATRMTAHNAMTKALLRRPLQE-----------IQMEKLKIGDQLLLEINDVTRAWGLEVDRVEL 217

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BLAST of PHB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q16TM5|BND7A_AEDAE (Band 7 protein AAEL010189 OS=Aedes aegypti OX=7159 GN=AAEL010189 PE=3 SV=1)

HSP 1 Score: 293.893 bits (751), Expect = 4.511e-97
Identity = 175/279 (62.72%), Postives = 219/279 (78.49%), Query Frame = 3

Query:  276 VEKKEFENIDDSSIHEQRGVTCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIES 1112
            V KK     +D S  E      I+  L++++VVLT PFSLL+C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI+ Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS ++Q++       L  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ +L Y ++S
Sbjct:   15 VTKKSSPEAEDDSNGEASTCGRILIFLSWVLVVLTMPFSLLVCFKVVQEYERAVIFRLGRLVQGGAKGPGIFFILPCIDAYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGSMQLS-------LDEATEAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDILTYFMKS 286

[Close]

BLAST of PHB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7PPU9|BND7A_ANOGA (Band 7 protein AGAP004871 OS=Anopheles gambiae OX=7165 GN=AGAP004871 PE=3 SV=3)

HSP 1 Score: 290.041 bits (741), Expect = 9.595e-96
Identity = 171/261 (65.52%), Postives = 214/261 (81.99%), Query Frame = 3

Query:  336 TC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIES 1112
            TC  I+  L++++VVLT PFSLL+C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI+ Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS ++Q++       L  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ +L Y ++S
Sbjct:   19 TCGRILIFLSWVLVVLTMPFSLLVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDAYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGSMQLS-------LDEATEAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDILTYFMKS 272

[Close]

BLAST of PHB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9VZA4|BND7A_DROME (Band 7 protein CG42540 OS=Drosophila melanogaster OX=7227 GN=CG42540 PE=2 SV=2)

HSP 1 Score: 290.426 bits (742), Expect = 6.373e-93
Identity = 169/265 (63.77%), Postives = 213/265 (80.38%), Query Frame = 3

Query:  327 RGVTC--IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            +  TC  ++  L+  +V++T PFSL +C K+VQEYERAVIFRLGRL  GGAKGPGIFFILPCI++Y +VDLRT ++DVPPQEVLT+DSVTV VDAVV YR+ NA VS+ANVE+AH STRL+AQ+TLRN +GT++L EILSER +IS  +QV       QL  AT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EAS+++ +S  A+QLRYLQTL  ++ EK STI+FPLP+ L+ Y +++N
Sbjct:  170 KASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQV-------QLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFLKTN 427

[Close]

BLAST of PHB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q19958|STO2_CAEEL (Stomatin-2 OS=Caenorhabditis elegans OX=6239 GN=sto-2 PE=3 SV=4)

HSP 1 Score: 282.337 bits (721), Expect = 1.903e-91
Identity = 167/251 (66.53%), Postives = 209/251 (83.27%), Query Frame = 3

Query:  354 LAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            L++I+V+ TFP S+  C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+YTKVDLRT+SF VPPQE+LT+DSVT  VDAV+ YRI NA VSVANVE+AH STRL+AQ+TLRN+LGT++LSEILS+RE+++ ++Q         L  AT  WGI++ERVEIKD RLP  LQR+MAAEAEA REARAK IA+EGE+ AS AL++A+ ++ +S  A+QLRYLQTL +VA EK STIIFPLP+ L+++LI
Sbjct:  131 LSWIMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVDLRTVSFSVPPQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNMLGTRSLSEILSDRETLAASMQT-------ILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATREARAKVIAAEGEQKASRALRDAASVIAQSPAALQLRYLQTLNSVAAEKNSTIIFPLPMELVRHLI 374

[Close]

BLAST of PHB domain-containing protein vs. UniProt/SwissProt
Match: sp|Q27433|MEC2_CAEEL (Mechanosensory protein 2 OS=Caenorhabditis elegans OX=6239 GN=mec-2 PE=1 SV=1)

HSP 1 Score: 283.493 bits (724), Expect = 1.916e-90
Identity = 180/334 (53.89%), Postives = 242/334 (72.46%), Query Frame = 3

Query:  126 SKNSEQQRFYSCNSDQ-ENNQSRFYEDFEFNEINNYEISSFIEKPEIKFDHVEKKEFENIDD----SSIHEQRGVTC-IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            S +S+     S +SD+ EN  +R  +  E +      IS+  +   +K +   +K+ E  +     ++I  + GV   I+TIL+Y+++  T P S  +CIK+VQEYERAVIFRLGRL  GGAKGPGIFFI+PCI+TY KVDLR +SF+VPPQE+L++DSVTV VDAVV +RI NA +SV NVEDA +ST+L+AQ+TLRN+LGTK L+E+LS+RE+IS  +Q         L  AT PWG+++ERVE+KD RLP  LQR+MAAEAEAAREARAK I +EGE+ AS ALKEA++++ ES +A+QLRYLQTL +++ EK STIIFP P+ LL   ++
Sbjct:   45 SSSSKDDDLLSTSSDEVENMATRTLQQLEES---TSIISANSDDDSVKKEKQAEKDVEKGNGKEEKANIQNEFGVCGWILTILSYLLIFFTLPISACMCIKVVQEYERAVIFRLGRLMPGGAKGPGIFFIVPCIDTYRKVDLRVLSFEVPPQEILSKDSVTVAVDAVVYFRISNATISVTNVEDAARSTKLLAQTTLRNILGTKTLAEMLSDREAISHQMQTT-------LDEATEPWGVKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIVAEGEQKASRALKEAAEVIAESPSALQLRYLQTLNSISAEKNSTIIFPFPIDLLSAFLQ 368

[Close]

BLAST of PHB domain-containing protein vs. TrEMBL
Match: T1G0K7 (PHB domain-containing protein OS=Helobdella robusta OX=6412 GN=20214605 PE=4 SV=1)

HSP 1 Score: 306.605 bits (784), Expect = 6.657e-100
Identity = 182/261 (69.73%), Postives = 218/261 (83.52%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI-ESNSK 1121
            ++TI+++I++  TFP SL  C+K+VQEYERAVIFRLGRL +GGAKGPGIFF+LPCIE+YTKVDLRT+SFDVPPQEVLT+DSVTV VDAVV YR+ NA VSVANVE+AH STRL+AQ+TLRNVLGTKNLSEILSERE+IS ++Q       E L  AT  WGI +ERVEIKD RLP  LQR+MAAEAEA REA+AK IA+EGE  A+ +LKEAS ++N+SSTA+QLRYLQTL  ++ EK STIIFPLP+ LL + I +S SK
Sbjct:    8 LLTIMSWIIIAFTFPVSLCTCLKVVQEYERAVIFRLGRLLHGGAKGPGIFFVLPCIESYTKVDLRTVSFDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSVANVENAHHSTRLLAQTTLRNVLGTKNLSEILSEREAISSSMQ-------ETLDDATEHWGIMVERVEIKDVRLPIQLQRAMAAEAEATREAKAKVIAAEGENQAAHSLKEASDVINKSSTALQLRYLQTLNTISAEKNSTIIFPLPIELLTHFIRKSQSK 261

[Close]

BLAST of PHB domain-containing protein vs. TrEMBL
Match: R7V575 (PHB domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_172850 PE=4 SV=1)

HSP 1 Score: 304.294 bits (778), Expect = 8.277e-99
Identity = 183/260 (70.38%), Postives = 217/260 (83.46%), Query Frame = 3

Query:  330 GVTC---IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQY 1100
            G+ C   ++TI ++ VV LTFP SL +C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+YTKVDLRT+SFDVPPQEVLT+DSVTV VDAVV YR+ NA VSVANVE+AH STRL+AQ+TLRNVLGTKNL+EILSERE+IS ++Q         L SAT  WGI++ERVEIKD RLP  LQR+MAAEAEAAREARAK IA+EGE  A+ ALKEAS+++NESS+A+QLRYLQTL  ++ EK STIIFPLP+  L +
Sbjct:   26 GLGCCGWLLTIFSWCVVCLTFPLSLCVCMKVVQEYERAVIFRLGRLLSGGAKGPGIFFVLPCIESYTKVDLRTVSFDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSVANVENAHHSTRLLAQTTLRNVLGTKNLAEILSEREAISNSMQT-------ALDSATDQWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGENKAAHALKEASEVMNESSSALQLRYLQTLNTISAEKNSTIIFPLPIEFLSH 278

[Close]

BLAST of PHB domain-containing protein vs. TrEMBL
Match: A0A267DM56 (PHB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011143g3 PE=4 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 4.981e-97
Identity = 176/258 (68.22%), Postives = 213/258 (82.56%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            ++T  +Y +V +TFP SL +C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+Y+KVDLRT+SFDVPPQEVLT+DSVTV VDAVV YR+ NA VSVANVE+AH STRL+AQ+TLRNVLGTKNL+EILSERE+IS ++Q       + L SAT  WGI +ERVEIKD RLP  LQR MAAEAEA REARAK IA+EGE+ AS ALKEAS +++ES+TA+QLRYLQT+ +++ EK STIIFPLP+  +   + S 
Sbjct:  101 VLTFFSYFIVGITFPMSLFVCLKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYSKVDLRTVSFDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSVANVENAHHSTRLLAQTTLRNVLGTKNLAEILSERENISNSMQ-------DILASATDSWGICVERVEIKDVRLPVQLQRVMAAEAEADREARAKVIAAEGEQKASRALKEASDVISESATALQLRYLQTMTSISAEKNSTIIFPLPLDFMANFMNSG 351

[Close]

BLAST of PHB domain-containing protein vs. TrEMBL
Match: A0A267GHU2 (PHB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011143g1 PE=4 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 6.320e-97
Identity = 175/258 (67.83%), Postives = 213/258 (82.56%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESN 1115
            ++T  +Y +V +TFP S+ +C+K+VQEYERAVIFRLGRL  GGAKGPGIFF+LPCIE+Y+KVDLRT+SFDVPPQEVLT+DSVTV VDAVV YR+ NA VSVANVE+AH STRL+AQ+TLRNVLGTKNL+EILSERE+IS ++Q       + L SAT  WGI +ERVEIKD RLP  LQR MAAEAEA REARAK IA+EGE+ AS ALKEAS +++ES+TA+QLRYLQT+ +++ EK STIIFPLP+  +   + S 
Sbjct:  102 VLTFFSYFIVGITFPMSMFVCLKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYSKVDLRTVSFDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSVANVENAHHSTRLLAQTTLRNVLGTKNLAEILSERENISNSMQ-------DILASATDSWGICVERVEIKDVRLPVQLQRVMAAEAEADREARAKVIAAEGEQKASRALKEASDVISESATALQLRYLQTMTSISAEKNSTIIFPLPLDFMANFMNSG 352

[Close]

BLAST of PHB domain-containing protein vs. TrEMBL
Match: A0A1S3JRG5 (band 7 protein AGAP004871 OS=Lingula unguis OX=7574 GN=LOC106175292 PE=4 SV=1)

HSP 1 Score: 298.901 bits (764), Expect = 1.906e-96
Identity = 176/256 (68.75%), Postives = 215/256 (83.98%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            I+  +++++VV TFPFSL  C+K+VQEYERAVIFRLGRL  GGAKGPG+FF+LPCIE YTKVDLRT+SFDVPPQE+LT+DSVT+ VDAVV YRI NA +SVANVEDAH ST+L+AQ++LRNVLGTKNL+EILS+RE+IS  +Q         L  AT PWGI++ERVE+KDCRLP  LQR+MAAEAEAAREARAK IA+EGE+ A+ ALKEA+ ++ ES +A+QLRYLQTL +++ EK STIIFPLPV LL  LI+
Sbjct:   49 ILVFISWVLVVCTFPFSLCSCVKVVQEYERAVIFRLGRLVGGGAKGPGMFFVLPCIEDYTKVDLRTVSFDVPPQEILTKDSVTISVDAVVYYRIQNATISVANVEDAHGSTKLLAQTSLRNVLGTKNLAEILSDREAISSTMQ-------SGLDEATDPWGIKVERVEVKDCRLPIQLQRAMAAEAEAAREARAKVIAAEGEQKAARALKEAADVIAESPSALQLRYLQTLNSISAEKNSTIIFPLPVDLLSGLIK 297

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Cavefish
Match: stoml3b (stomatin (EPB72)-like 3b [Source:ZFIN;Acc:ZDB-GENE-050417-366])

HSP 1 Score: 263.077 bits (671), Expect = 2.974e-85
Identity = 161/265 (60.75%), Postives = 208/265 (78.49%), Query Frame = 3

Query:  324 QRGVTC---IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            +RG+ C   I+  L+ +  VL FP  + +CIKIVQEYERAVIFRLGR+T   AKGPGIFFILPC +++ KVD+RTISFD+PPQE+LT+DSVTV VD VV +R+ + + SVANV +A  STRL+AQ+TLRNVLGTKNL+E+LS+RE IS ++Q         L  AT  WGI++ERVEIKD +LP+ LQR+MAAEAEA+REARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK ST+IFP+P+ +L + ++
Sbjct:   85 KRGLGCCGWILVALSTLFTVLLFPVMIFVCIKIVQEYERAVIFRLGRITARKAKGPGIFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTVSVDGVVYFRVSDPIASVANVTNADYSTRLLAQTTLRNVLGTKNLAEVLSDREGISHSMQ-------STLDEATDSWGIKVERVEIKDVKLPQQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTVIFPVPMDILGHFLK 342

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Cavefish
Match: zgc:112408 (erythrocyte band 7 integral membrane protein-like [Source:NCBI gene;Acc:103025999])

HSP 1 Score: 254.603 bits (649), Expect = 1.105e-82
Identity = 146/251 (58.17%), Postives = 203/251 (80.88%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLL 1094
            ++T L++++++ TFP S+  C+KIV+EYERAVIFRLGRL  GGAKGPGIF+ILPC++T+ KVDLRT+SF++PPQEVLT+DSVT+ VD VV YR+ N  VS+  VEDA+ +T+++AQ+TLRN+LGTK+L++IL +RE ++  ++       E + SA+  WGI++ERVE+KD +LP  LQR+MAAEAEA REARAK IA+EGE  AS ALKEA+ +++ES  A+QLRYLQTL  +A E+ ST++FP+P+ L+
Sbjct:   38 LLTALSFLLILATFPISVWSCMKIVKEYERAVIFRLGRL-LGGAKGPGIFWILPCVDTFRKVDLRTVSFNIPPQEVLTKDSVTIMVDGVVYYRVFNPTVSITKVEDANMATQMLAQTTLRNMLGTKSLADILRDREEMAEQME-------EVIYSASKNWGIKVERVELKDVKLPHTLQRAMAAEAEATREARAKVIAAEGEMKASCALKEAALVMSESPAALQLRYLQTLAEIATERNSTVVFPIPMDLI 280

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BLAST of PHB domain-containing protein vs. Ensembl Cavefish
Match: stoml3a (stomatin (EPB72)-like 3a [Source:ZFIN;Acc:ZDB-GENE-070620-18])

HSP 1 Score: 253.062 bits (645), Expect = 5.288e-82
Identity = 154/239 (64.44%), Postives = 196/239 (82.01%), Query Frame = 3

Query:  381 FPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQ 1097
             P ++ +CIKIVQEYERAVIFRLGR+     KGPG+FF+LPC +T TKVDLR  SFD+PPQE+LT+DSVTV VD VV +R+ + ++SVANV +A  STRL+AQ+TLRNVLGTK+L+E+LS+RESIS  +Q++       L  AT+PWGI++ERVEIKD +LP+ LQR+MAAEAEA+REARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A+EK STIIFPLP+ +LQ
Sbjct:   57 LPITIFMCIKIVQEYERAVIFRLGRILDRKPKGPGMFFLLPCTDTMTKVDLRAKSFDIPPQEILTKDSVTVCVDGVVYFRVSDPIMSVANVVNADMSTRLLAQTTLRNVLGTKSLAEVLSDRESISHNMQIS-------LDEATHPWGIKVERVEIKDVKLPQQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVIAESPSALQLRYLQTLNTIASEKNSTIIFPLPMDMLQ 288

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BLAST of PHB domain-containing protein vs. Ensembl Cavefish
Match: zgc:112408 (erythrocyte band 7 integral membrane protein-like [Source:NCBI gene;Acc:103025999])

HSP 1 Score: 251.136 bits (640), Expect = 1.107e-81
Identity = 140/251 (55.78%), Postives = 192/251 (76.49%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLL 1094
            ++T L++++++ TFP S+  C+KIV+EYERAVIFRLGRL  GGAKGPGIF+ILPC++T+ KVDLRT+SF++PPQEVLT+DSVT+ VD VV YR+ N  VS+  VEDA+ +T+++AQ+TLRN+LGTK+L                +  +  E++      WGI++ERVE+KD +LP  LQR+MAAEAEA REARAK IA+EGE  AS ALKEA+ +++ES  A+QLRYLQTL  +A E+ ST++FP+P+ L+
Sbjct:   27 LLTALSFLLILATFPISVWSCMKIVKEYERAVIFRLGRL-LGGAKGPGIFWILPCVDTFRKVDLRTVSFNIPPQEVLTKDSVTIMVDGVVYYRVFNPTVSITKVEDANMATQMLAQTTLRNMLGTKSL---------------ADILRDREEMAEQMENWGIKVERVELKDVKLPHTLQRAMAAEAEATREARAKVIAAEGEMKASCALKEAALVMSESPAALQLRYLQTLAEIATERNSTVVFPIPMDLI 261

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BLAST of PHB domain-containing protein vs. Ensembl Cavefish
Match: stom (stomatin [Source:NCBI gene;Acc:103034070])

HSP 1 Score: 251.521 bits (641), Expect = 1.903e-81
Identity = 152/237 (64.14%), Postives = 193/237 (81.43%), Query Frame = 3

Query:  399 ICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            +CIKIV+EYERA+IFRLGR+  GGAKGPG+FFILPC +++  VD+RTI+FD+PPQEVLT+DSVTV VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNL+EILS+RE I+ ++Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK STIIFPLP+ ++Q  ++
Sbjct:   60 MCIKIVKEYERAIIFRLGRILRGGAKGPGLFFILPCTDSFINVDMRTITFDIPPQEVLTKDSVTVSVDGVVYYRVQNATLAVANITNADAATRLLAQTTLRNVLGTKNLAEILSDREEIAHSMQ-------STLDEATDDWGIKVERVEIKDVKLPLQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIIFPLPMDMMQSFLK 289

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BLAST of PHB domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006522.1 (pep scaffold:Pmarinus_7.0:GL477331:35910:45947:-1 gene:ENSPMAG00000005879.1 transcript:ENSPMAT00000006522.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 265.003 bits (676), Expect = 1.271e-87
Identity = 159/272 (58.46%), Postives = 210/272 (77.21%), Query Frame = 3

Query:  303 DDSSIHEQRGVTCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNS 1118
            DD  +        ++ IL+ +VVVLTFP S+  C+K+V+EYERAV+FRLG+L  GGA GPG+F +LPCI+T+ KVD+RT++FDVPPQE+LTRDSVTV VDAVV YR+ +A  +V NV  A  +TRL+AQ+ LRNVLGT++LS+I+SERE I+ ++Q +       L  AT PWGI+++RVEIKD RLP  +QR+MAAEAEA REARAK +++EGE +AS +LKEA+ +L ESS A+QLRYLQTL N+A E+ STIIFP+P+ +L  L  SNS
Sbjct:   11 DDKRLQTAGCCEKLLGILSMVVVVLTFPLSVWFCLKVVREYERAVVFRLGKLLPGGAIGPGLFLVLPCIDTFVKVDMRTVTFDVPPQEILTRDSVTVAVDAVVYYRVHDATAAVTNVVFADGATRLLAQTALRNVLGTRSLSDIVSEREVIARSMQTS-------LDEATEPWGIKVQRVEIKDVRLPSQMQRAMAAEAEAIREARAKVVSAEGEMNASRSLKEAAIVLGESSGALQLRYLQTLNNIAAERNSTIIFPIPIDILSAL-RSNS 274

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008297.1 (pep scaffold:Pmarinus_7.0:GL485275:4696:10707:1 gene:ENSPMAG00000007488.1 transcript:ENSPMAT00000008297.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 264.233 bits (674), Expect = 3.372e-87
Identity = 163/298 (54.70%), Postives = 222/298 (74.50%), Query Frame = 3

Query:  237 SSFIEKPEIKFDHVEKKEFENIDDSSIHEQRGVTC---IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNSK 1121
            + + EK  I F    K+   +  D S     GV C   ++  L+Y ++++TFP S+ +C KIVQEYERAVIF LGR+  GGAKGPG+F+I+PC + + KVD+RT++FD+PPQE+LT+DSVTV VD VV YR+ NA++SVAN+ +A+ +T+L+AQ+TLRNVLGTKNL+EILS+RE I+  +Q+        L  AT  WGI++ERV+IKD +LP+ LQR+MAAEAEA REARAK I++EGE +AS ALKEA++++ E+  A+QLRYLQTL  +A E+ STIIFPLP+ LLQ +  S  K
Sbjct:    2 AGWQEKNHIHF----KQMLSSFRDPS---SSGVGCCGYLLIGLSYFLILITFPISIWMCFKIVQEYERAVIFTLGRIKPGGAKGPGLFWIVPCTDNFVKVDMRTVNFDIPPQEILTKDSVTVSVDGVVYYRVQNAILSVANITNANSATQLLAQTTLRNVLGTKNLAEILSDREEIAHTMQLT-------LDEATDNWGIKLERVDIKDVKLPQQLQRAMAAEAEATREARAKVISAEGEMNASRALKEAAQVMGEAPAAMQLRYLQTLNTIAAERNSTIIFPLPMDLLQGMGASWKK 285

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BLAST of PHB domain-containing protein vs. Ensembl Sea Lamprey
Match: NPHS2 (NPHS2 stomatin family member, podocin [Source:HGNC Symbol;Acc:HGNC:13394])

HSP 1 Score: 136.346 bits (342), Expect = 2.450e-38
Identity = 92/228 (40.35%), Postives = 135/228 (59.21%), Query Frame = 3

Query:  375 LTFPFSLLIC---IKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQ-----LTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTL 1034
            L+ P  +  C   +++V EYERAVIFRLGRL    A GPG+FFILPC++TY KVDLR  + +VP  EV+T DS++V+V    +YR+  A +   +V    ++  L+ Q+ +R ++  K+LS I            + +R    Q     L +    WGI++ER EI D R+P  LQ+S+  EA+A R ARA+ IA++ EK  +L L  A+++L     A+ LRYL TL
Sbjct:   15 LSLPCLVYSCCAGLQVVYEYERAVIFRLGRLLSVRANGPGLFFILPCLDTYQKVDLRMRTLEVPLHEVITSDSLSVRVSVACHYRVERASIWAVSVAQPLEALGLVLQAKVRALVAKKDLSYI------------LQHRPELAQHTKECLDAVVGSWGIKVERAEINDVRIPLELQKSVCVEADANRAARARLIAAQAEKQTALELSGAARVLAAVPGALSLRYLHTL 230

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BLAST of PHB domain-containing protein vs. Ensembl Sea Lamprey
Match: stoml1 (stomatin (EPB72)-like 1 [Source:ZFIN;Acc:ZDB-GENE-070209-241])

HSP 1 Score: 117.087 bits (292), Expect = 8.875e-30
Identity = 69/188 (36.70%), Postives = 109/188 (57.98%), Query Frame = 3

Query:  309 SSIHEQRGV--------TCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEI 848
            S  HE  GV        + +IT L ++ +VLTFP S+  C+KIV ++ER V+FRLGRL      GPG+  +LPCI+ + +VD R  +F+VPP   +TRD   V V A V  R+   V+ +   +D ++S+R  A + L ++L   +L E+ SE   ++  + +       ++T  T PWG+++ERVE+
Sbjct:   34 SRTHEAEGVESWLSWFCSLVITSLTFVFMVLTFPLSVWFCLKIVPQHERIVVFRLGRLR--APLGPGVALVLPCIDRWRRVDTRPRAFNVPPCRAMTRDGALVSVGADVRVRVHCPVLLLTAAQDVNRSSRSAAHTALASLLPRHSLHELQSESAKMADELAL-------EVTKVTEPWGLEVERVEL 212

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004822.1 (pep scaffold:Pmarinus_7.0:GL478327:3419:6286:-1 gene:ENSPMAG00000004386.1 transcript:ENSPMAT00000004822.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.9442 bits (180), Expect = 3.706e-17
Identity = 36/63 (57.14%), Postives = 46/63 (73.02%), Query Frame = 3

Query:  300 IDDSSIHEQRGVTCIIT-ILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPG 485
            I DS   +  G   I+  I + I++V+TFP S+ +CIK+VQEYERAVIFRLGR+  GGAKGPG
Sbjct:    4 IPDSQREDGYGACGILLLIFSAIMLVVTFPISVWLCIKVVQEYERAVIFRLGRIAKGGAKGPG 66

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Nematostella
Match: EDO43326 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ15])

HSP 1 Score: 280.026 bits (715), Expect = 3.710e-93
Identity = 166/277 (59.93%), Postives = 213/277 (76.90%), Query Frame = 3

Query:  276 VEKKEFENIDDSSIHEQRGVTCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            VE+         S HE+      +T ++ ++ ++TFP ++ +C+KIVQEYERAVIFRLGRL  GGAKGPG+FFILPCI++Y KVDLR +SFDVPPQE+LT+DSVTV VDAVV +RI NA +S+ NVE+A+ STRL+AQ+TLRN LGTKNL+EILS+R+ IS  +Q         L  AT PWG+++ER+E+KD RLP+ LQR+MAAEAEA REARAK IA+EGE +AS +LKEAS I++ES  A+QLRYLQTL  ++ EK STIIFPLP+  L  L+
Sbjct:   10 VEQPSTSGHHQGSDHERGFFYFFLTGVSILIFIITFPIAIFMCLKIVQEYERAVIFRLGRLLKGGAKGPGLFFILPCIDSYQKVDLRVVSFDVPPQEILTKDSVTVAVDAVVYFRIANATMSITNVENANASTRLLAQTTLRNTLGTKNLTEILSQRDEISQTMQ-------SSLDEATDPWGVKVERIEVKDVRLPQQLQRAMAAEAEATREARAKIIAAEGEMNASRSLKEASDIISESPQALQLRYLQTLTTISAEKNSTIIFPLPIDFLSKLL 279

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Nematostella
Match: EDO31853 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWR9])

HSP 1 Score: 262.307 bits (669), Expect = 1.413e-86
Identity = 156/256 (60.94%), Postives = 201/256 (78.52%), Query Frame = 3

Query:  345 ITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIES 1112
            ITI  YI V+ TFPFSL  C+K+V EYERAVIFR+GR+  GGA+GPGIFF+LPCI+ + KVD+RT+SFDVPPQEVLT+DSVTV VDAVV +R+ NA VS+ NVE+A  ST+L+AQ+TLRN++G+K L EILSER++IS  ++         L  AT PWG+++ERVE+KD RLP  LQR+MAAEAEA REA+AK I +EGE  +S ALK A+++L+ S +A+QLRYLQTL  ++ EK STIIFPLP+ LL   + +
Sbjct:    8 ITICCYIGVICTFPFSLFFCLKVVSEYERAVIFRIGRILSGGARGPGIFFVLPCIDEFRKVDIRTVSFDVPPQEVLTKDSVTVTVDAVVYFRVENATVSITNVENAFGSTKLLAQTTLRNMMGSKLLCEILSERDNISATMK-------GMLDEATGPWGVRVERVEMKDVRLPVQLQRAMAAEAEAHREAKAKFIVAEGEMKSSHALKNAAEVLDGSPSALQLRYLQTLNTISAEKNSTIIFPLPMNLLNRFMNA 256

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Nematostella
Match: EDO28629 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T5Y2])

HSP 1 Score: 236.884 bits (603), Expect = 1.308e-76
Identity = 142/256 (55.47%), Postives = 182/256 (71.09%), Query Frame = 3

Query:  345 ITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIES 1112
            ITI  YI V+ TFPFSL  C+K+V EYERAVIFR+GR+  GGA+GPGIFF+LPCI+ + KVD+RT+SFDVPPQEVLT+DSVTV VDAVV +R+ NA VS+ NVE+A  S    AQ+  R     ++               Q +Y K+      AT PWG+++ERVE+KD RLP  LQR+MAAEAEA REA+AK I +EGE  +S ALK A+++L+ S +A+QLRYLQTL  ++ EK STIIFPLP+ LL   + +
Sbjct:    8 ITICCYIGVICTFPFSLFFCLKVVSEYERAVIFRIGRILSGGARGPGIFFVLPCIDEFRKVDIRTVSFDVPPQEVLTKDSVTVTVDAVVYFRVENATVSITNVENAFDSVTPSAQAFAR-----QHPRAYWLPAFFHPQGKQ-SYLKNL--CPQATGPWGVRVERVEMKDVRLPVQLQRAMAAEAEAHREAKAKFIVAEGEMKSSHALKNAAEVLDGSPSALQLRYLQTLNTISAEKNSTIIFPLPMNLLNRFMNA 255

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Nematostella
Match: EDO43325 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ14])

HSP 1 Score: 199.904 bits (507), Expect = 3.451e-62
Identity = 92/127 (72.44%), Postives = 113/127 (88.98%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKN 722
            IIT L+ ++ VLTFP ++  CIKIVQEYERAVIFRLGRL  GGAKGPG+FFILPCI++Y KVDLRT+SFDVPPQE+LT+DSVTV VDAVV +RI NA +S+ NVE+A++STRL+AQ+TLRN+LGTK+
Sbjct:    6 IITGLSILLFVLTFPIAVFFCIKIVQEYERAVIFRLGRLLEGGAKGPGMFFILPCIDSYQKVDLRTVSFDVPPQEILTKDSVTVAVDAVVYFRIANATMSITNVENANRSTRLLAQTTLRNILGTKS 132

HSP 2 Score: 67.781 bits (164), Expect = 4.916e-13
Identity = 34/60 (56.67%), Postives = 43/60 (71.67%), Query Frame = 3

Query:  942 GEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNSK 1121
            GE +AS ALKEAS I++ES  A+QLRYLQTL  ++ EK STIIFPLP+  +   I  + K
Sbjct:  198 GEMNASRALKEASDIISESPQALQLRYLQTLTTISAEKNSTIIFPLPIDFIAKFIPDHKK 257

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Nematostella
Match: EDO43324 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ13])

HSP 1 Score: 180.644 bits (457), Expect = 1.908e-55
Identity = 125/255 (49.02%), Postives = 167/255 (65.49%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            ++T+++ IV+VLTFP S+  C+KIVQEYERAVIFRLGRL  GGAKGPG+                     +P            ++D                  +A+ STRL+AQ+TLRN+LGTKNL+EILS+R+ IS  +Q         L  AT PWG+++ER+E+KD RLP+ +QR+MAAEAEA+R+ARAK IA+EGE +AS +LK+AS IL+ES  AIQLRYLQTL  ++ EK STIIFPLP+ +L + +
Sbjct:    9 VLTVISVIVIVLTFPLSVWFCLKIVQEYERAVIFRLGRLLQGGAKGPGM---------------------IP------------RLDP-----------------NANGSTRLLAQTTLRNILGTKNLTEILSQRDEISQTMQ-------STLDEATDPWGVKVERIEVKDVRLPQQMQRAMAAEAEASRDARAKIIAAEGEMNASRSLKDASDILSESPQAIQLRYLQTLTTISAEKNSTIIFPLPIDMLSHFL 206

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Medaka
Match: STOML3 (erythrocyte band 7 integral membrane protein-like [Source:NCBI gene;Acc:101171931])

HSP 1 Score: 264.233 bits (674), Expect = 1.985e-86
Identity = 160/256 (62.50%), Postives = 202/256 (78.91%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIE 1109
            ++ I + I VV TFP +  +C+KIV+EYERAVIFRLGR+     KGPG+FF+LPC + + KVDLRT+SFD+PPQE+LT+DSVTV VD VV +RI   + SVANV +AH STRL+AQ+TLRNVLGTKNLSE+LS+RE IS+++Q       E L  AT PWGI++ERVEIKD  LP+ LQR+MAAEAEA+REARAK IA+EGE  AS ALKEAS ++ E+ +A+QLRYLQTL  +A EK STIIFPLP+ +LQ  ++
Sbjct:   38 LLVIFSLIFVVATFPLTGFMCVKIVKEYERAVIFRLGRIVDRKPKGPGLFFVLPCTDNFVKVDLRTVSFDIPPQEILTKDSVTVSVDGVVYFRIHCPISSVANVSNAHSSTRLLAQTTLRNVLGTKNLSELLSDREGISLSMQ-------ESLDDATEPWGIKVERVEIKDVTLPQQLQRAMAAEAEASREARAKIIAAEGEMKASRALKEASLVMAEAPSALQLRYLQTLSTIAAEKNSTIIFPLPIDMLQSFMQ 286

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Medaka
Match: stom (stomatin [Source:NCBI gene;Acc:101167971])

HSP 1 Score: 253.062 bits (645), Expect = 3.012e-82
Identity = 152/241 (63.07%), Postives = 195/241 (80.91%), Query Frame = 3

Query:  390 SLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIES 1112
            S+ +CIKIV+EYERA+IFRLGR+  GGAKGPG+FFILPC +++  VD+RTI+FD+PPQE+LT+DSVTV VD VV YR+ NA ++VAN+ +A  +TRL+AQ+TLRNVLGTKNL+EILS+RE I+ ++Q         L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEA REARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK STIIFPLP+ ++Q  I++
Sbjct:   51 SVWMCIKIVKEYERAIIFRLGRIVKGGAKGPGLFFILPCTDSFINVDMRTITFDIPPQEILTKDSVTVSVDGVVYYRVQNATLAVANITNADAATRLLAQTTLRNVLGTKNLAEILSDREEIAHSMQ-------SSLDDATDAWGIKVERVEIKDVKLPLQLQRAMAAEAEATREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIIFPLPLEMMQGFIKN 284

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Medaka
Match: stoml3b (erythrocyte band 7 integral membrane protein [Source:NCBI gene;Acc:101162729])

HSP 1 Score: 251.906 bits (642), Expect = 6.184e-82
Identity = 162/270 (60.00%), Postives = 206/270 (76.30%), Query Frame = 3

Query:  309 SSIHEQRG-VTCI---ITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            S + E+ G + C+   I IL+    VL FP ++  C+KIVQEYERAVIFRLGR+     KGPGIFFILPC ++  KVDLR ISFD+PPQE+LT+DSVTV VD VV +R+ + + SVANV +A+ STRL+AQ+TLRNVLGTKNL+E+LS+RE I+ ++Q N       L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK STIIFPLP+ ++ + +
Sbjct:   10 SYVSERTGSLGCLGWFIVILSGFFTVLLFPITICYCLKIVQEYERAVIFRLGRIIDKKPKGPGIFFILPCTDSLVKVDLRIISFDIPPQEILTKDSVTVSVDGVVYFRVSDPIASVANVTNANYSTRLLAQTTLRNVLGTKNLAEVLSDREGIAHSMQSN-------LDEATDNWGIKVERVEIKDVKLPHQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLSTIAAEKNSTIIFPLPMDVISHFM 272

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Medaka
Match: stoml3b (erythrocyte band 7 integral membrane protein-like [Source:NCBI gene;Acc:101173000])

HSP 1 Score: 251.906 bits (642), Expect = 6.191e-82
Identity = 162/268 (60.45%), Postives = 205/268 (76.49%), Query Frame = 3

Query:  315 IHEQRG-VTCI---ITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLI 1106
            + E+ G + CI   I IL+ + V L FP ++  C K VQEYERAVIFRLGR+T    KGPGIFFILPC ++  KVDLRT+SFD+PPQE+LT+DSVTV VD VV +R+ + + SVANV +A  STRL+AQ+TLRNVLGTKNL+E+LS+RE I+ ++Q N       L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A EK STIIFPLP+ ++ + +
Sbjct:    8 VSERTGSLGCIGWLIVILSGLFVFLLFPVTIWFCFKTVQEYERAVIFRLGRITDRKPKGPGIFFILPCTDSLVKVDLRTVSFDIPPQEILTKDSVTVSVDGVVYFRVSDPIASVANVTNADFSTRLLAQTTLRNVLGTKNLAEVLSDREGIAHSMQSN-------LDEATDNWGIKVERVEIKDVKLPFQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIIFPLPMDVISHFM 268

[Close]

BLAST of PHB domain-containing protein vs. Ensembl Medaka
Match: stoml3b (erythrocyte band 7 integral membrane protein [Source:NCBI gene;Acc:101162729])

HSP 1 Score: 236.113 bits (601), Expect = 1.062e-75
Identity = 157/267 (58.80%), Postives = 199/267 (74.53%), Query Frame = 3

Query:  270 DHVEKKEFENIDDSS-IHEQRG-VTCI---ITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEK 1055
            D +E +     DD+  I E+ G + C+   I IL+    VL FP ++  C+KIVQEYERAVIFRLGR+     KGPGIFFILPC ++  KVDLR ISFD+PPQE+LT+DSVTV VD VV +R+ + + SVANV +A+ STRL+AQ+TLRNVLGTKNL+E+LS+RE I+ ++Q N       L  AT  WGI++ERVEIKD +LP  LQR+MAAEAEAAREARAK IA+EGE +AS ALKEAS ++ ES +A+QLRYLQTL  +A E+
Sbjct:    5 DKIESQRQRQEDDNGFISERTGSLGCLGWFIVILSGFFTVLLFPITICYCLKIVQEYERAVIFRLGRIIDKKPKGPGIFFILPCTDSLVKVDLRIISFDIPPQEILTKDSVTVSVDGVVYFRVSDPIASVANVTNANYSTRLLAQTTLRNVLGTKNLAEVLSDREGIAHSMQSN-------LDEATDNWGIKVERVEIKDVKLPHQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASLVIAESPSALQLRYLQTLSTIAAER 264

[Close]

BLAST of PHB domain-containing protein vs. Planmine SMEST
Match: SMESG000021969.1 (SMESG000021969.1)

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 364/373 (97.59%), Postives = 366/373 (98.12%), Query Frame = 3

Query:    3 MNSKFAHKHKYAMPKIFIFPDPEDSDVKPTEYTTEWSDFKMSKNSEQQRFYSCNSDQENNQSRFYEDFEFNEINNYEISSFIEKPEIKFDHVEKKEFENIDDSSIHEQRGVTCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNSK 1121
            MNSKFAHKHKYAMPKIFIFPDPEDSDVKPTEYTTEWSDFKMSKNSEQQRFYSCNSDQENNQSRFYEDFEFNEINNYEISSFIEKPEIKFDHVEKKEFENIDDSSIHEQ+GVTCIITILAY+VVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNLSEILSERESISIAVQ       EQLTSATYPWGIQMERVEIKDCRLPKILQRSMAAEAEAAREARAKEIASEGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNSK
Sbjct:    1 MNSKFAHKHKYAMPKIFIFPDPEDSDVKPTEYTTEWSDFKMSKNSEQQRFYSCNSDQENNQSRFYEDFEFNEINNYEISSFIEKPEIKFDHVEKKEFENIDDSSIHEQQGVTCIITILAYVVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNLSEILSERESISIAVQ-------EQLTSATYPWGIQMERVEIKDCRLPKILQRSMAAEAEAAREARAKEIASEGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNSK 366

[Close]

BLAST of PHB domain-containing protein vs. Planmine SMEST
Match: SMESG000068910.1 (SMESG000068910.1)

HSP 1 Score: 275.018 bits (702), Expect = 8.884e-91
Identity = 168/259 (64.86%), Postives = 207/259 (79.92%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNS 1118
            I+  L+YI +VLT P SL +CIK+V EYERAVIFRLGR+   GAKGPG+FF++PC++   K+DLRT++FDVPPQEVLTRDSVTV VDAVV YRI N VV+V NVEDA +STRL+A +TLRNVLGTKNL+EILSERESIS  +Q         L  AT PWG+++ERVE+KD RLP  LQR+MAAEAEAAREARAK IA+EGE+ AS AL+EA+ ++N+S  A+QLRYLQTL  ++ EK STIIFPLP+ +L Y + S +
Sbjct:   37 ILIGLSYISIVLTLPVSLFLCIKVVAEYERAVIFRLGRILSEGAKGPGLFFVVPCMDVIRKIDLRTVTFDVPPQEVLTRDSVTVAVDAVVYYRIHNPVVAVTNVEDADRSTRLLAATTLRNVLGTKNLAEILSERESISTMMQ-------NMLDDATDPWGVKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKASHALREAADVINKSKFALQLRYLQTLNTISAEKNSTIIFPLPMDMLSYFMSSET 288

[Close]

BLAST of PHB domain-containing protein vs. Planmine SMEST
Match: SMESG000028915.1 (SMESG000028915.1)

HSP 1 Score: 265.388 bits (677), Expect = 2.406e-86
Identity = 162/260 (62.31%), Postives = 203/260 (78.08%), Query Frame = 3

Query:  342 IITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNSK 1121
            ++  L Y+++  T P SL+ CIKI+ EYERAVIFR GR+   G KGPGI F+LPC+ET  +VDLRT++F+VPPQEVLT+DSVTV VDAVV YRI N +VS+ NVED   STRL+A +TLRNVLGTKNLSEILSERE IS  +QV        L  AT+PWG+++ERVEIKD RLP  LQR+MAAEAEA REA AK IA+EGE+ +S+ALK AS+I+ +S TA+QLRYLQTL  +++E++STIIFP P+ LL   ++SN K
Sbjct:   90 MLVFLIYVLLFFTMPLSLIFCIKIISEYERAVIFRFGRVPKYGTKGPGIIFVLPCLETVKRVDLRTLTFNVPPQEVLTKDSVTVAVDAVVYYRIYNPIVSIINVEDCDFSTRLLAATTLRNVLGTKNLSEILSERELISGLMQV-------MLDDATHPWGVKVERVEIKDVRLPLQLQRAMAAEAEATREANAKVIAAEGEQKSSIALKAASEIICQSPTALQLRYLQTLSALSSEQSSTIIFPFPIELLYKYVKSNIK 342

[Close]

BLAST of PHB domain-containing protein vs. Planmine SMEST
Match: SMESG000009300.1 (SMESG000009300.1)

HSP 1 Score: 265.003 bits (676), Expect = 5.112e-86
Identity = 170/267 (63.67%), Postives = 204/267 (76.40%), Query Frame = 3

Query:  297 NIDDSSIHEQRGVT--CIITIL--AYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPV 1085
            N+D S I +    T  C I ++  +Y +V LTFP SL+ CIK+V EYERAVIFRLGR+  GGAKGPG+FFILPCI+   KVDLRT++FDVPPQEVLT+DSVTV VDAVV YRI N VVSV NVED  +STRL+A +TLRNVLGTKNLSEILSER+SIS  +Q         L  AT PWG+++ERVE+KD RLP  LQR+MAAEAEA REARAK IA+EGE+ ++ ALKEA+  +N S  A+QLRYLQTL  ++ E  STIIFP P+
Sbjct:   79 NMDASEISQMDKQTSFCRIALILVSYFLVALTFPISLIGCIKVVAEYERAVIFRLGRILTGGAKGPGLFFILPCIDQIRKVDLRTVTFDVPPQEVLTKDSVTVAVDAVVYYRIYNPVVSVINVEDCDRSTRLLAATTLRNVLGTKNLSEILSERDSISSMMQ-------SMLDDATDPWGVKVERVEVKDVRLPVQLQRAMAAEAEATREARAKVIAAEGEQKSARALKEAADTINRSPMALQLRYLQTLSTISAEHNSTIIFPFPI 338

[Close]

BLAST of PHB domain-containing protein vs. Planmine SMEST
Match: SMESG000059569.1 (SMESG000059569.1)

HSP 1 Score: 247.669 bits (631), Expect = 3.768e-79
Identity = 155/284 (54.58%), Postives = 210/284 (73.94%), Query Frame = 3

Query:  267 FDHVEKKEFENIDDSSIHEQRGVTCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLGRLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVDAVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNXXXXXXXXXXXXXAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMXXXXXXXXXXXXXXXXXXGEKSASLALKEASKILNESSTAIQLRYLQTLINVANEKTSTIIFPLPVGLLQYLIESNS 1118
            F++VE +  E   +S++    G    I  ++Y+   +TFPFSL  C+K+V +YERAVIFRLGRL     KGPG+ F+LPC+++   VDLRT +F+VP QEVLT+DSVTV VDAVV YRI N ++SV NVEDA++STRL+AQ+TLRNVLGT +L ++L+ERE I+  +Q         L +AT  WG+++ERV+IKD RLP  LQR+MAAEAEAAREA+AK IA+EGEK AS+ALK A+  +++   A+QLRYLQTL ++++EK STIIFP+P+  L    +SN+
Sbjct:   78 FENVENQTGEKGYNSAMS---GCESAIQAMSYLTAAITFPFSLFACLKVVAQYERAVIFRLGRLISKQPKGPGLVFVLPCLDSMKLVDLRTFTFNVPTQEVLTKDSVTVAVDAVVYYRIFNPIMSVVNVEDANRSTRLLAQTTLRNVLGTVDLYQLLAEREQIASNMQ-------GCLDTATETWGVKVERVDIKDVRLPIQLQRAMAAEAEAAREAKAKVIAAEGEKRASVALKAAAIQISDCPIALQLRYLQTLRSISDEKNSTIIFPIPIDFLNLFSDSNA 351

The following BLAST results are available for this feature:

BLAST of PHB domain-containing protein vs. Ensembl Human
BLAST of PHB domain-containing protein vs. Ensembl Celegans
BLAST of PHB domain-containing protein vs. Ensembl Fly
BLAST of PHB domain-containing protein vs. Ensembl Zebrafish
BLAST of PHB domain-containing protein vs. Ensembl Xenopus
BLAST of PHB domain-containing protein vs. Ensembl Mouse
BLAST of PHB domain-containing protein vs. UniProt/SwissProt
BLAST of PHB domain-containing protein vs. TrEMBL
BLAST of PHB domain-containing protein vs. Ensembl Cavefish
BLAST of PHB domain-containing protein vs. Ensembl Sea Lamprey
BLAST of PHB domain-containing protein vs. Ensembl Yeast
BLAST of PHB domain-containing protein vs. Ensembl Nematostella
BLAST of PHB domain-containing protein vs. Ensembl Medaka
BLAST of PHB domain-containing protein vs. Planmine SMEST

BLAST of PHB domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
STOM	4.782e-88	61.09	stomatin [Source:HGNC Symbol;Acc:HGNC:3383]	[more]
STOML3	3.915e-82	56.00	stomatin like 3 [Source:HGNC Symbol;Acc:HGNC:19420...	[more]
STOML3	2.796e-81	56.82	stomatin like 3 [Source:HGNC Symbol;Acc:HGNC:19420...	[more]
STOM	1.966e-57	62.99	stomatin [Source:HGNC Symbol;Acc:HGNC:3383]	[more]
NPHS2	7.344e-55	43.63	NPHS2 stomatin family member, podocin [Source:HGNC...	[more]

BLAST of PHB domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sto-2	5.079e-93	66.53	Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q1995...	[more]
mec-2	8.621e-93	53.89	Mechanosensory protein 2 [Source:UniProtKB/Swiss-...	[more]
sto-2	9.520e-93	66.53	Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q1995...	[more]
sto-2	1.029e-92	66.53	Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q1995...	[more]
sto-2	1.496e-92	66.53	Stomatin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q1995...	[more]

BLAST of PHB domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG42540	1.160e-94	63.77	gene:FBgn0260657 transcript:FBtr0301096	[more]
CG42540	1.316e-94	63.77	gene:FBgn0260657 transcript:FBtr0344807	[more]
CG42540	1.320e-94	63.77	gene:FBgn0260657 transcript:FBtr0333583	[more]
CG42540	1.766e-94	63.77	gene:FBgn0260657 transcript:FBtr0333584	[more]
CG42540	1.913e-94	63.77	gene:FBgn0260657 transcript:FBtr0301097	[more]

BLAST of PHB domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
stoml3b	2.294e-84	61.96	stomatin (EPB72)-like 3b [Source:ZFIN;Acc:ZDB-GENE...	[more]
zgc:112408	1.678e-83	58.17	zgc:112408 [Source:ZFIN;Acc:ZDB-GENE-050417-63]	[more]
zgc:112408	2.227e-83	58.17	zgc:112408 [Source:ZFIN;Acc:ZDB-GENE-050417-63]	[more]
stom	1.577e-82	59.16	stomatin [Source:ZFIN;Acc:ZDB-GENE-980526-486]	[more]
stom	1.577e-82	59.16	stomatin [Source:ZFIN;Acc:ZDB-GENE-980526-486]	[more]

BLAST of PHB domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
myo10.2	9.737e-88	57.04	myosin 10, gene 2 [Source:Xenbase;Acc:XB-GENE-5995...	[more]
myo10.2	9.338e-87	60.84	myosin 10, gene 2 [Source:Xenbase;Acc:XB-GENE-5995...	[more]
myo10.2	3.591e-86	61.96	myosin 10, gene 2 [Source:Xenbase;Acc:XB-GENE-5995...	[more]
atp8b3	2.565e-77	56.75	ATPase, aminophospholipid transporter, class I, ty...	[more]
ENSXETT00000046764.1	1.024e-62	53.70	pep primary_assembly:Xenopus_tropicalis_v9.1:2:223...	[more]

BLAST of PHB domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Stom	3.667e-89	58.87	stomatin [Source:MGI Symbol;Acc:MGI:95403]	[more]
Stoml3	3.496e-79	60.58	stomatin (Epb7.2)-like 3 [Source:MGI Symbol;Acc:MG...	[more]
Nphs2	2.244e-59	45.67	nephrosis 2, podocin [Source:MGI Symbol;Acc:MGI:21...	[more]
Nphs2	1.112e-41	35.29	nephrosis 2, podocin [Source:MGI Symbol;Acc:MGI:21...	[more]
Stoml1	5.027e-23	35.40	stomatin-like 1 [Source:MGI Symbol;Acc:MGI:1916356...	[more]

BLAST of PHB domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q16TM5\|BND7A_AEDAE	4.511e-97	62.72	Band 7 protein AAEL010189 OS=Aedes aegypti OX=7159...	[more]
sp\|Q7PPU9\|BND7A_ANOGA	9.595e-96	65.52	Band 7 protein AGAP004871 OS=Anopheles gambiae OX=...	[more]
sp\|Q9VZA4\|BND7A_DROME	6.373e-93	63.77	Band 7 protein CG42540 OS=Drosophila melanogaster ...	[more]
sp\|Q19958\|STO2_CAEEL	1.903e-91	66.53	Stomatin-2 OS=Caenorhabditis elegans OX=6239 GN=st...	[more]
sp\|Q27433\|MEC2_CAEEL	1.916e-90	53.89	Mechanosensory protein 2 OS=Caenorhabditis elegans...	[more]

BLAST of PHB domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
T1G0K7	6.657e-100	69.73	PHB domain-containing protein OS=Helobdella robust...	[more]
R7V575	8.277e-99	70.38	PHB domain-containing protein OS=Capitella teleta ...	[more]
A0A267DM56	4.981e-97	68.22	PHB domain-containing protein OS=Macrostomum ligna...	[more]
A0A267GHU2	6.320e-97	67.83	PHB domain-containing protein OS=Macrostomum ligna...	[more]
A0A1S3JRG5	1.906e-96	68.75	band 7 protein AGAP004871 OS=Lingula unguis OX=757...	[more]

BLAST of PHB domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
stoml3b	2.974e-85	60.75	stomatin (EPB72)-like 3b [Source:ZFIN;Acc:ZDB-GENE...	[more]
zgc:112408	1.105e-82	58.17	erythrocyte band 7 integral membrane protein-like ...	[more]
stoml3a	5.288e-82	64.44	stomatin (EPB72)-like 3a [Source:ZFIN;Acc:ZDB-GENE...	[more]
zgc:112408	1.107e-81	55.78	erythrocyte band 7 integral membrane protein-like ...	[more]
stom	1.903e-81	64.14	stomatin [Source:NCBI gene;Acc:103034070]	[more]

BLAST of PHB domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000006522.1	1.271e-87	58.46	pep scaffold:Pmarinus_7.0:GL477331:35910:45947:-1 ...	[more]
ENSPMAT00000008297.1	3.372e-87	54.70	pep scaffold:Pmarinus_7.0:GL485275:4696:10707:1 ge...	[more]
NPHS2	2.450e-38	40.35	NPHS2 stomatin family member, podocin [Source:HGNC...	[more]
stoml1	8.875e-30	36.70	stomatin (EPB72)-like 1 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
ENSPMAT00000004822.1	3.706e-17	57.14	pep scaffold:Pmarinus_7.0:GL478327:3419:6286:-1 ge...	[more]

BLAST of PHB domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PHB domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO43326	3.710e-93	59.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31853	1.413e-86	60.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28629	1.308e-76	55.47	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43325	3.451e-62	72.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43324	1.908e-55	49.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of PHB domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
STOML3	1.985e-86	62.50	erythrocyte band 7 integral membrane protein-like ...	[more]
stom	3.012e-82	63.07	stomatin [Source:NCBI gene;Acc:101167971]	[more]
stoml3b	6.184e-82	60.00	erythrocyte band 7 integral membrane protein [Sour...	[more]
stoml3b	6.191e-82	60.45	erythrocyte band 7 integral membrane protein-like ...	[more]
stoml3b	1.062e-75	58.80	erythrocyte band 7 integral membrane protein [Sour...	[more]

BLAST of PHB domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000021969.1	0.000e+0	97.59	SMESG000021969.1	[more]
SMESG000068910.1	8.884e-91	64.86	SMESG000068910.1	[more]
SMESG000028915.1	2.406e-86	62.31	SMESG000028915.1	[more]
SMESG000009300.1	5.112e-86	63.67	SMESG000009300.1	[more]
SMESG000059569.1	3.768e-79	54.58	SMESG000059569.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30031859 ID=SMED30031859|Name=PHB domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1127bp
TAATGAACAGTAAATTTGCTCACAAACACAAATATGCCATGCCAAAAATA
TTCATTTTCCCTGATCCAGAAGATTCCGACGTCAAACCGACTGAATACAC
GACAGAATGGAGTGATTTTAAAATGTCGAAAAATTCCGAACAGCAACGAT
TCTATTCATGCAACTCGGATCAGGAAAACAATCAAAGCAGATTCTATGAG
GATTTTGAGTTCAACGAAATAAACAATTATGAAATTTCTTCTTTCATTGA
AAAACCGGAAATAAAGTTTGATCACGTGGAAAAGAAAGAATTTGAAAACA
TCGACGATTCTTCAATACATGAGCAACGAGGAGTAACGTGCATAATAACA
ATTTTAGCCTACATCGTTGTAGTGTTGACTTTCCCATTTTCATTACTAAT
ATGCATAAAAATTGTTCAAGAATATGAGAGAGCAGTTATTTTTCGTTTAG
GAAGACTGACTTATGGTGGGGCTAAAGGTCCAGGAATTTTCTTCATACTT
CCATGCATCGAGACGTACACAAAAGTAGATCTACGAACAATTTCCTTTGA
TGTGCCGCCACAAGAGGTTTTAACAAGAGATTCGGTCACAGTTAAGGTTG
ATGCCGTTGTGAACTATCGCATCTGTAATGCCGTCGTTTCTGTAGCCAAT
GTGGAAGATGCACATCAAAGCACCCGACTTATAGCTCAATCAACGTTACG
CAACGTCCTTGGAACAAAAAATCTTTCAGAAATATTGTCAGAGCGAGAAA
GTATAAGCATTGCAGTTCAAGTAAATTATAGAAAGTCTTTTGAACAATTG
ACATCAGCTACATATCCCTGGGGAATACAAATGGAGAGAGTAGAAATCAA
AGATTGCCGGTTACCAAAGATTCTTCAAAGATCCATGGCTGCCGAAGCGG
AAGCAGCGAGAGAAGCTAGAGCTAAAGAAATAGCGTCAGAGGGAGAAAAG
AGTGCCTCACTGGCATTAAAAGAAGCCAGTAAAATTTTAAACGAATCTTC
AACTGCTATTCAGCTGCGTTATCTTCAAACATTAATAAATGTCGCCAACG
AAAAAACGTCAACAATTATATTCCCCCTTCCAGTCGGTCTGCTGCAATAT
TTGATAGAATCCAATTCGAAATGAAAA

protein sequence of SMED30031859-orf-1

>SMED30031859-orf-1 ID=SMED30031859-orf-1|Name=SMED30031859-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=374bp
MNSKFAHKHKYAMPKIFIFPDPEDSDVKPTEYTTEWSDFKMSKNSEQQRF
YSCNSDQENNQSRFYEDFEFNEINNYEISSFIEKPEIKFDHVEKKEFENI
DDSSIHEQRGVTCIITILAYIVVVLTFPFSLLICIKIVQEYERAVIFRLG
RLTYGGAKGPGIFFILPCIETYTKVDLRTISFDVPPQEVLTRDSVTVKVD
AVVNYRICNAVVSVANVEDAHQSTRLIAQSTLRNVLGTKNLSEILSERES
ISIAVQVNYRKSFEQLTSATYPWGIQMERVEIKDCRLPKILQRSMAAEAE
AAREARAKEIASEGEKSASLALKEASKILNESSTAIQLRYLQTLINVANE
KTSTIIFPLPVGLLQYLIESNSK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR043202	Band-7_stomatin-like
IPR036013	Band_7/SPFH_dom_sf
IPR001972	Stomatin_HflK_HflKC_fam
IPR001107	Band_7

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001972	Stomatin/HflK/HflC family	PRINTS	PR00721	STOMATIN	coord: 294..315 score: 70.78 coord: 189..210 score: 58.12 coord: 140..162 score: 66.46 coord: 319..342 score: 54.76
IPR001107	Band 7 domain	SMART	SM00244	PHB_4	coord: 133..299 e-value: 9.2E-50 score: 181.3
IPR001107	Band 7 domain	PFAM	PF01145	Band_7	coord: 137..315 e-value: 5.0E-27 score: 95.1
None	No IPR available	GENE3D	G3DSA:3.30.479.30		coord: 163..301 e-value: 2.3E-49 score: 168.8
None	No IPR available	PANTHER	PTHR10264:SF114	BAND 7 PROTEIN CG42540	coord: 86..371
None	No IPR available	TMHMM	TMhelix		coord: 111..133
IPR043202	Band-7 stomatin-like	PANTHER	PTHR10264	BAND 7 PROTEIN-RELATED	coord: 86..371
IPR036013	Band 7/SPFH domain superfamily	SUPERFAMILY	SSF117892	Band 7/SPFH domain	coord: 166..306

Main menu

PHB domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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