SMED30031809

Overview


Name	SMED30031809
Smed ID	SMED30031809
Length (bp)	1637

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30031809 (SMED30031809) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30031809 (SMED30031809) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30031809

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
parapharyngeal region	SMED30031809	h1SMcG0010400	SmedASXL_005444	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30031809	h1SMcG0010400	dd_Smed_v4_24918_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30031809	h1SMcG0010400	dd_Smed_v6_24918_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Alignments

SMED30031809 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.002300:12183..16633 -	7916

Homology

[Close]

BLAST of SMED30031809 vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 80.8777 bits (198), Expect = 7.608e-16
Identity = 55/233 (23.61%), Postives = 112/233 (48.07%), Query Frame = -1

Query:  744 LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1433
            + ++  K +L II     R      F+GRTS+GKSS+IN  + + +LP+G G ++N  + ++ +   K +L  + +D  K  + +  L      +        ++VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +++ + H     ++   EL +    E    IFF+S  E
Sbjct:   55 VEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKE 287

[Close]

BLAST of SMED30031809 vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 80.4925 bits (197), Expect = 2.780e-15
Identity = 55/233 (23.61%), Postives = 112/233 (48.07%), Query Frame = -1

Query:  744 LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1433
            + ++  K +L II     R      F+GRTS+GKSS+IN  + + +LP+G G ++N  + ++ +   K +L  + +D  K  + +  L      +        ++VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +++ + H     ++   EL +    E    IFF+S  E
Sbjct:   55 VEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKE 287

[Close]

Query:  744 LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1433
            + ++  K +L II     R      F+GRTS+GKSS+IN  + + +LP+G G ++N  + ++ +   K +L  + +D  K  + +  L      +        ++VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +++ + H     ++   EL +    E    IFF+S  E
Sbjct:   55 VEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKE 287

[Close]

BLAST of SMED30031809 vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877])

HSP 1 Score: 75.0998 bits (183), Expect = 1.491e-13
Identity = 48/215 (22.33%), Postives = 104/215 (48.37%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   + FL  + ++  +  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +E+ + H     ++  +EL +    +    IFF+S  E
Sbjct:   94 RRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKE 308

[Close]

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   + FL  + ++  +  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +E+ + H     ++  +EL +    +    IFF+S  E
Sbjct:   94 RRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. Ensembl Celegans
Match: fzo-1 (Transmembrane GTPase fzo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q23424])

HSP 1 Score: 85.1149 bits (209), Expect = 4.255e-17
Identity = 65/231 (28.14%), Postives = 112/231 (48.48%), Query Frame = -1

Query:  726 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIP-------IKVFFGYKQEV----VINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDI-IHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNF 1379
            R+    VF+GRTS GKS+ IN  + E +LP G G  +   ++++ S+     L +  +D  ++ ++  L  I      EN  +P       +KVF   K E     ++  ++ I D+PG++   +F+S I   C +AD+ V++ ++ S     EKN  L+   K S  N  I+ + +D      ++ +++ K H      +  +EL +  E E N  IFF+S  E  ES  
Sbjct:   98 RDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSEGEVGHLQL--DDNPQKIDMKMLGKIGHALSDENSDLPAMGQDSLLKVFHPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDELEVCSEREVNDRIFFVSSREVLESRL 326

[Close]

BLAST of SMED30031809 vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070910)

HSP 1 Score: 77.0258 bits (188), Expect = 1.897e-14
Identity = 56/222 (25.23%), Postives = 109/222 (49.10%), Query Frame = -1

Query:  744 IRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENF--AIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKN-HENIAENYFSNELHIKKEYEENKNIFFLSGFE 1397
            IR    R+     F+GRTS GKSS+IN  + E ILP+G G  +N   +++ S   + +L  + ++  ++  +  +K +A     E    +  +++F+  ++  ++  ++   D+PG++     +  I + C NAD+ V+++++ S     EK        K S  N  I+ + +D   N  +  E  K+ H     ++ + EL +  E E  + +FF+S  E
Sbjct:  129 IREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSE--EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARE 348

[Close]

BLAST of SMED30031809 vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070909)

HSP 1 Score: 77.0258 bits (188), Expect = 1.897e-14
Identity = 56/222 (25.23%), Postives = 109/222 (49.10%), Query Frame = -1

Query:  744 IRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENF--AIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKN-HENIAENYFSNELHIKKEYEENKNIFFLSGFE 1397
            IR    R+     F+GRTS GKSS+IN  + E ILP+G G  +N   +++ S   + +L  + ++  ++  +  +K +A     E    +  +++F+  ++  ++  ++   D+PG++     +  I + C NAD+ V+++++ S     EK        K S  N  I+ + +D   N  +  E  K+ H     ++ + EL +  E E  + +FF+S  E
Sbjct:  129 IREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSE--EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARE 348

[Close]

BLAST of SMED30031809 vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0343373)

HSP 1 Score: 74.3294 bits (181), Expect = 1.456e-13
Identity = 55/226 (24.34%), Postives = 108/226 (47.79%), Query Frame = -1

Query:  744 IRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENF--AIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDE-----ICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1397
            IR    R+     F+GRTS GKSS+IN  + E ILP+G G  +N   +++ S   + +L  + ++  ++  +  +K +A     E    +  +++F+  ++  ++  ++   D+PG++     +  I + C NAD+ V+++++ S     EK        K S  N  I+ + +D   N  +  E     +   H     ++ + EL +  E E  + +FF+S  E
Sbjct:  129 IREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSE--EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARE 352

[Close]

BLAST of SMED30031809 vs. Ensembl Fly
Match: fzo (gene:FBgn0011596 transcript:FBtr0084399)

HSP 1 Score: 61.2326 bits (147), Expect = 1.522e-9
Identity = 38/170 (22.35%), Postives = 88/170 (51.76%), Query Frame = -1

Query:  882 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKT-FLCVKENDTIKQTEIAPLKLIAKQNPIENF--AIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYD 1379
            R+     F+GRTS GKS++IN  + E ILP+  G  ++   +++ + + +T  + V++ D  +  E++ L  +A  +       +  ++V     +  +++ ++ + DTPG++   Q +  +   C +AD+ ++++++ S    +E+       +K S  N  I+ + +D
Sbjct:   84 RDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQED--EHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWD 251

[Close]

BLAST of SMED30031809 vs. Ensembl Zebrafish
Match: MFN1 (mitofusin 1a [Source:NCBI gene;Acc:100329462])

HSP 1 Score: 87.0409 bits (214), Expect = 8.126e-18
Identity = 85/370 (22.97%), Postives = 167/370 (45.14%), Query Frame = -1

Query:  462 FENILPIIAKLNDFVIILKCFASKWNLKSGDFSEIE-----LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDI-IHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNE--FNGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKV 1541
            F  +L  + + +DFV         W  +S D   +      L ++   R+L +I+    R      F+GRTS GKS+IIN  + E +LP+G G  +N  + ++ +   + +L  ++++  K  E +  L      N  ++    ++VF+   + V++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D  +   +  +++ K H +   ++  +EL +    +    IFF+S             +KE    R +  +Q      G + E  F  +L   +  E  F++  ++      F +      Q++E +K+ M A+ NI S   KV
Sbjct:   23 FHQLLEFVKEGSDFV------EDTW--RSEDLDNVAEEDQCLQIQTCFRKLTVIKDVLDRRHMKVAFFGRTSNGKSTIINAMLRERVLPSGIGHTTNCFLSVEGTDGEQAYLTTEDSEERKGIETVNHLAHALHMNRNQDSGCLVRVFWPKTKCVLLRDDLVLMDSPGIDVTSELDSWIDKFCLDADVFVLVANSESTIMNTEKHFFHKVNERISKPNIFILNNRWDASVLEPEYLEDVRKQHMDRCVSFLVDELKVVDLNKAPDRIFFVS-------------AKEVLSARIHR-AQGMPETGGALAE-GFQERLMEFQSFERTFEEFISQSAVKTKFEQHTIRAWQIIESVKAIMDAI-NISSAEKKV 368

[Close]

BLAST of SMED30031809 vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 81.6481 bits (200), Expect = 1.941e-16
Identity = 57/226 (25.22%), Postives = 109/226 (48.23%), Query Frame = -1

Query:  744 LQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIE---NFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1406
            L II+    R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   K FL  K   + ++  I  +  +A    ++   +    +KVF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D      ++ +++ K H +   N+   EL +    +    IFF+S  E
Sbjct:   65 LSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFL--KTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKE 288

[Close]

BLAST of SMED30031809 vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 81.2629 bits (199), Expect = 2.535e-16
Identity = 57/226 (25.22%), Postives = 109/226 (48.23%), Query Frame = -1

Query:  744 LQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIE---NFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1406
            L II+    R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   K FL  K   + ++  I  +  +A    ++   +    +KVF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D      ++ +++ K H +   N+   EL +    +    IFF+S  E
Sbjct:   65 LSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFL--KTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKE 288

[Close]

BLAST of SMED30031809 vs. Ensembl Zebrafish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 82.4185 bits (202), Expect = 4.714e-16
Identity = 53/215 (24.65%), Postives = 106/215 (49.30%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R     VF+GRTS GKSS+IN  + + +LP+G G  +N  + ++ +   ++FL  + +D  K  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   N  ++ +E+ + H +   ++  +EL +         IFF+S  E
Sbjct:   94 RRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNESFLLTEGSDERKSVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASANEPEYMEEVRRQHMDRCTSFLVDELRVVDRSHAGDRIFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 81.6481 bits (200), Expect = 9.171e-16
Identity = 72/300 (24.00%), Postives = 133/300 (44.33%), Query Frame = -1

Query:  564 LEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIE---NFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEIS---KEKYQFRENAFSQFRNR----ISGEMEETDFTRKLNYLKKSEEIFDDLFNEFN 1427
            +E    +L II+    R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   K FL  K   + ++  I  +  +A    ++   +    +KVF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D      ++ +++ K H +   N+   EL +    +    IFF+S  E   S           E +Q R   F  F       IS    +T F +     K+  E   D+ ++ N
Sbjct:   58 IESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFL--KTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGGALAEGFQDRLKEFQNFERSFEECISHSAVKTKFEQHTIRAKQITETVKDIMDQIN 355

[Close]

BLAST of SMED30031809 vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 85.1149 bits (209), Expect = 9.842e-17
Identity = 86/358 (24.02%), Postives = 172/358 (48.04%), Query Frame = -1

Query:  324 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFT--EMMTETA-QLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEI 1379
            RN K   F+GRTS+GKS++IN  + + +LP+G G  +N  + ++ ++  K +L  + ++  K  + +  L      +        + VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D   +  ++ +++ K H    +++  +EL +    E  K IFF+S  E      N  + K          +Q        + E   TR L + +K E++F++  ++ + + T  E  T TA Q+ + +K+ M A+ NI + + +V   ++   ++     +K     +  + E +IL+I K +NE V S +
Sbjct:   90 RNMKV-AFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEV----LNARMHK----------AQGMPEAGAALAEGFHTRFLEF-QKFEKLFEECISQ-SAVKTKFEQHTITAKQITDTVKAIMDAI-NIKAADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAM 429

[Close]

BLAST of SMED30031809 vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 84.7297 bits (208), Expect = 1.287e-16
Identity = 86/358 (24.02%), Postives = 172/358 (48.04%), Query Frame = -1

Query:  324 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFT--EMMTETA-QLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEI 1379
            RN K   F+GRTS+GKS++IN  + + +LP+G G  +N  + ++ ++  K +L  + ++  K  + +  L      +        + VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D   +  ++ +++ K H    +++  +EL +    E  K IFF+S  E      N  + K          +Q        + E   TR L + +K E++F++  ++ + + T  E  T TA Q+ + +K+ M A+ NI + + +V   ++   ++     +K     +  + E +IL+I K +NE V S +
Sbjct:   90 RNMKVA-FFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEV----LNARMHK----------AQGMPEAGAALAEGFHTRFLEF-QKFEKLFEECISQ-SAVKTKFEQHTITAKQITDTVKAIMDAI-NIKAADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAM 429

[Close]

BLAST of SMED30031809 vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 84.7297 bits (208), Expect = 1.317e-16
Identity = 86/358 (24.02%), Postives = 172/358 (48.04%), Query Frame = -1

Query:  324 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFT--EMMTETA-QLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEI 1379
            RN K   F+GRTS+GKS++IN  + + +LP+G G  +N  + ++ ++  K +L  + ++  K  + +  L      +        + VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D   +  ++ +++ K H    +++  +EL +    E  K IFF+S  E      N  + K          +Q        + E   TR L + +K E++F++  ++ + + T  E  T TA Q+ + +K+ M A+ NI + + +V   ++   ++     +K     +  + E +IL+I K +NE V S +
Sbjct:   93 RNMKVA-FFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEV----LNARMHK----------AQGMPEAGAALAEGFHTRFLEF-QKFEKLFEECISQ-SAVKTKFEQHTITAKQITDTVKAIMDAI-NIKAADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAM 432

[Close]

BLAST of SMED30031809 vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 84.7297 bits (208), Expect = 1.365e-16
Identity = 86/358 (24.02%), Postives = 172/358 (48.04%), Query Frame = -1

Query:  324 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFT--EMMTETA-QLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEI 1379
            RN K   F+GRTS+GKS++IN  + + +LP+G G  +N  + ++ ++  K +L  + ++  K  + +  L      +        + VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D   +  ++ +++ K H    +++  +EL +    E  K IFF+S  E      N  + K          +Q        + E   TR L + +K E++F++  ++ + + T  E  T TA Q+ + +K+ M A+ NI + + +V   ++   ++     +K     +  + E +IL+I K +NE V S +
Sbjct:   85 RNMKVA-FFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEV----LNARMHK----------AQGMPEAGAALAEGFHTRFLEF-QKFEKLFEECISQ-SAVKTKFEQHTITAKQITDTVKAIMDAI-NIKAADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAM 424

[Close]

BLAST of SMED30031809 vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 84.7297 bits (208), Expect = 1.485e-16
Identity = 86/358 (24.02%), Postives = 172/358 (48.04%), Query Frame = -1

Query:  324 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFT--EMMTETA-QLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEI 1379
            RN K   F+GRTS+GKS++IN  + + +LP+G G  +N  + ++ ++  K +L  + ++  K  + +  L      +        + VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   K S  N  I+ + +D   +  ++ +++ K H    +++  +EL +    E  K IFF+S  E      N  + K          +Q        + E   TR L + +K E++F++  ++ + + T  E  T TA Q+ + +K+ M A+ NI + + +V   ++   ++     +K     +  + E +IL+I K +NE V S +
Sbjct:   90 RNMKV-AFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEV----LNARMHK----------AQGMPEAGAALAEGFHTRFLEF-QKFEKLFEECISQ-SAVKTKFEQHTITAKQITDTVKAIMDAI-NIKAADKRVRCMVERENQNDRLEYVKTQMLILTEEIEKRILHITKEVNEQVSSAM 429

[Close]

BLAST of SMED30031809 vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230])

HSP 1 Score: 75.485 bits (184), Expect = 7.190e-14
Identity = 49/215 (22.79%), Postives = 102/215 (47.44%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS GKS++IN  + + +LP+G G  +N  + +  +   + FL  + ++  K  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK    K   + S  N  I+ + +D   +  ++ +E+ + H     ++  +EL +    +    IFF+S  E
Sbjct:   94 RRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230])

HSP 1 Score: 75.0998 bits (183), Expect = 1.107e-13
Identity = 49/215 (22.79%), Postives = 102/215 (47.44%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS GKS++IN  + + +LP+G G  +N  + +  +   + FL  + ++  K  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK    K   + S  N  I+ + +D   +  ++ +E+ + H     ++  +EL +    +    IFF+S  E
Sbjct:   94 RRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE 308

[Close]

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS GKS++IN  + + +LP+G G  +N  + +  +   + FL  + ++  K  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK    K   + S  N  I+ + +D   +  ++ +E+ + H     ++  +EL +    +    IFF+S  E
Sbjct:   94 RRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE 308

[Close]

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS GKS++IN  + + +LP+G G  +N  + +  +   + FL  + ++  K  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK    K   + S  N  I+ + +D   +  ++ +E+ + H     ++  +EL +    +    IFF+S  E
Sbjct:   94 RRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. Ensembl Mouse
Match: Mfn1 (mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664])

HSP 1 Score: 74.7146 bits (182), Expect = 1.508e-13
Identity = 50/215 (23.26%), Postives = 101/215 (46.98%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEKGQFESVILD-LCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS+GKSS+IN  + + +LP+G G  +N  + ++ +   K +L  + +D  K  + +  L      +        + VF+   +  ++  ++ + D+PG +      + +D  C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +++ + H     ++   EL +    E    IFF+S  E
Sbjct:   73 RRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKE 287

[Close]

BLAST of SMED30031809 vs. UniProt/SwissProt
Match: sp|Q23424|FZO1_CAEEL (Transmembrane GTPase fzo-1 OS=Caenorhabditis elegans OX=6239 GN=fzo-1 PE=3 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 5.412e-16
Identity = 65/231 (28.14%), Postives = 112/231 (48.48%), Query Frame = -1

Query:  726 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIP-------IKVFFGYKQEV----VINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDI-IHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNF 1379
            R+    VF+GRTS GKS+ IN  + E +LP G G  +   ++++ S+     L +  +D  ++ ++  L  I      EN  +P       +KVF   K E     ++  ++ I D+PG++   +F+S I   C +AD+ V++ ++ S     EKN  L+   K S  N  I+ + +D      ++ +++ K H      +  +EL +  E E N  IFF+S  E  ES  
Sbjct:   98 RDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSEGEVGHLQL--DDNPQKIDMKMLGKIGHALSDENSDLPAMGQDSLLKVFHPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDELEVCSEREVNDRIFFVSSREVLESRL 326

[Close]

BLAST of SMED30031809 vs. UniProt/SwissProt
Match: sp|Q8IWA4|MFN1_HUMAN (Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 SV=3)

HSP 1 Score: 80.4925 bits (197), Expect = 1.335e-14
Identity = 55/233 (23.61%), Postives = 112/233 (48.07%), Query Frame = -1

Query:  744 LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1433
            + ++  K +L II     R      F+GRTS+GKSS+IN  + + +LP+G G ++N  + ++ +   K +L  + +D  K  + +  L      +        ++VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +++ + H     ++   EL +    E    IFF+S  E
Sbjct:   55 VEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKE 287

[Close]

BLAST of SMED30031809 vs. UniProt/SwissProt
Match: sp|Q7YU24|MARF_DROME (Transmembrane GTPase Marf OS=Drosophila melanogaster OX=7227 GN=Marf PE=1 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 1.902e-13
Identity = 56/222 (25.23%), Postives = 109/222 (49.10%), Query Frame = -1

Query:  744 IRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENF--AIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKN-HENIAENYFSNELHIKKEYEENKNIFFLSGFE 1397
            IR    R+     F+GRTS GKSS+IN  + E ILP+G G  +N   +++ S   + +L  + ++  ++  +  +K +A     E    +  +++F+  ++  ++  ++   D+PG++     +  I + C NAD+ V+++++ S     EK        K S  N  I+ + +D   N  +  E  K+ H     ++ + EL +  E E  + +FF+S  E
Sbjct:  129 IREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSE--EKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARE 348

[Close]

BLAST of SMED30031809 vs. UniProt/SwissProt
Match: sp|Q8R4Z9|MFN1_RAT (Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 4.082e-13
Identity = 52/222 (23.42%), Postives = 103/222 (46.40%), Query Frame = -1

Query:  723 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEKGQFESVILD-LCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFN 1379
            R      F+GRTS+GKSS+IN  + + +LP+G G  +N  + ++ +   K +L  + +D  K  + +  L      +        + VF+   +  ++  ++ + D+PG +      + +D  C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +++ + H     ++   EL +    E    IFF+S  E   S  N
Sbjct:   73 RRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPLEARNRIFFVSAKEVLNSRMN 294

[Close]

BLAST of SMED30031809 vs. UniProt/SwissProt
Match: sp|O95140|MFN2_HUMAN (Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3)

HSP 1 Score: 75.0998 bits (183), Expect = 7.162e-13
Identity = 48/215 (22.33%), Postives = 104/215 (48.37%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   + FL  + ++  +  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +E+ + H     ++  +EL +    +    IFF+S  E
Sbjct:   94 RRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. TrEMBL
Match: A0A3S0ZZU2 (Dynamin-type G domain-containing protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_005131 PE=3 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 8.169e-18
Identity = 77/338 (22.78%), Postives = 161/338 (47.63%), Query Frame = -1

Query:  417 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIP----IKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFN--------DEISKEKYQFRENAFSQFRNR----ISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECV 1379
            R+    VF+GRTS GKS++IN  + + ILP+G G  ++  ++++ S + + FL    +DT K   I  +K +A  + + +  +     I++ +   +  ++ +++ + D+PG++     +S I + C +AD+ V++ ++ S     EK    K  ++ S  N  I+ + +D+    +D D++ + H     N+ SNEL +  +      +FF+S  E   +  N        D +    +Q R   FS F       IS    +T F +   + K+++EI   L       +T+ +T+  + ++  + +   ++ +      +  ++ +  K +VE V
Sbjct:   85 RDHMKVVFFGRTSNGKSTVINAMLRDKILPSGIGHTTHCFIQVEGSDSKEAFLLT--DDTDKPKSITDIKHLA--SALSSVRLSENSLIRILWPKDRCRLLREDVVLLDSPGIDVTPDLDSWIDNHCLDADVFVLVANAESTLMQTEKKFFHKVSSRLSCPNIFILQNRWDVSEMEEDIDQVKQQHLEGNTNFLSNELKVTDKKSAKDRVFFVSAREALATRVNSDKGLATPDRVLLPGFQARLFEFSNFEKEFEQCISHSAVQTKFEQ---HTKRAKEINSSLRKVMEEAYTKSLTQQDEQIQVRREKSSRLQQLDRQLDTLTSDMKVKIKIMVEDV 415

[Close]

BLAST of SMED30031809 vs. TrEMBL
Match: A0A437CEN8 (Dynamin-type G domain-containing protein OS=Oryzias javanicus OX=123683 GN=OJAV_G00169690 PE=3 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 4.859e-17
Identity = 89/366 (24.32%), Postives = 161/366 (43.99%), Query Frame = -1

Query:  462 NILPIIAKLNDFVIILKCFASKWNLKSGDFSEIE---LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQ-TEIAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEKGQ-FESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNE--FNGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKV 1535
            +I  I   L DFV     F     L+S D   IE   L ++    +L  IR   LR      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   + +L  +E++  +  + +  L      +P  + +  +KVF+   +  ++  ++ + D+PG +  Q  +S I   C +AD+ V++ ++ S     EK    K   + S  N  I+++ +D      D+  E+ K H +   ++ + EL +    E    IFF+S  E   S                  +Q      G + E  F  +L   ++ E  F++  +       F +      Q+ E IK+ M A+ NI S + K+
Sbjct:   18 SITSIFDLLLDFVKDGSAFVDA-ALQSDDLVAIEEQSLEMQSCATKLSTIRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDGDEAYLTAEESEERRSISTVNQLAHALHMDPTLDSSCLVKVFWPKSRCALLRNDLVLMDSPGTDVTQELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQEVRKQHLDRCVSFLAEELGVVGPNEAPGRIFFISAKEVLSSRMQR--------------AQGMPETGGALAE-GFHDRLTEFQRFERTFEEFISHSAVRTKFEQHTVRAWQITEAIKAVMDAI-NIASADRKI 366

[Close]

BLAST of SMED30031809 vs. TrEMBL
Match: A0A498SEU3 (Dynamin-type G domain-containing protein OS=Acanthocheilonema viteae OX=6277 GN=NAV_LOCUS5204 PE=3 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 1.422e-16
Identity = 74/281 (26.33%), Postives = 133/281 (47.33%), Query Frame = -1

Query:  630 KRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIP-------IKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNG-QDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE------KEESNFNDEISKEKYQFRENAF----SQFRNRISGEMEETDF 1415
            K  ++ IR   +R+T   VF+GRTS GKSS+IN  +   +LP G G  +   ++++ SQ  + F  V   D+ ++ +I  L+ I       N ++        ++VF+   +  ++  ++ I D+PG++   +F+S I   C +AD+ V++ ++ S     EK+   +  +K S  N  I+ + +D      ++  +I + H    + +  +EL +  E E    IFF+S  E      KE    +     E +Q+R   F    +QF   IS     T F
Sbjct:   78 KESIKTIRDMFMRDTMKVVFFGRTSNGKSSVINAMLHAKVLPQGMGHTTCCFLQVEGSQDDQKF--VLNEDSSERMDIEQLQKIGHAMSDSNVSLSAMGQDSLLRVFYPKSESRLLQNDVVIVDSPGVDLSPEFDSWIDKHCMDADVFVLVCNAESTLTQAEKSFFHRVSSKLSRPNIFILNNRWDASATEVENMQQIREQHMTRFKQFLVSELKVCSEAEATNRIFFISAREMLDIRLKERGVIHHAYQVEGHQYRAMEFCNFETQFEQLISKSAISTKF 356

[Close]

BLAST of SMED30031809 vs. TrEMBL
Match: A0A0R3QRG5 (Dynamin-type G domain-containing protein OS=Brugia timori OX=42155 GN=BTMF_LOCUS8351 PE=3 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.857e-16
Identity = 77/305 (25.25%), Postives = 140/305 (45.90%), Query Frame = -1

Query:  558 KRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIP-------IKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNG-QDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE------KEESNFNDEISKEKYQFRENAF----SQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGI 1415
            K  ++ IR   +R+T   VF+GRTS GKSS+IN  +   +LP G G  +   ++++ S   + F  V   D+ ++ +I  L+ +       N ++        + VF+      ++  ++ I D+PG++   QF+S I   C +AD+ V++ ++ S     EK+   +  +K S  N  I+ + +D      ++  +I + H      +  NEL +  E E    IFF+S  E      KE    +     E +Q+R   F    +QF   IS     T F     + +++ EI  ++ N  + +
Sbjct:   80 KDSIKTIRDMFMRDTMKVVFFGRTSNGKSSVINAMLHAKVLPQGMGHTTCCFLQVEGSPDDQKF--VLNEDSSERMDIEQLQKLGHAMSDSNVSLSAMGQDSLLHVFYPKSASRLLQNDVVIVDSPGVDLSPQFDSWIDKHCMDADVFVLVCNAESTLTQAEKSFFHRVSSKLSRPNIFILNNRWDASATEVENMQQIREQHMTRFRQFLVNELKVCSEAEAANRIFFISAREMLDVRLKERGVIHHAYQVEGHQYRAMQFCNFETQFEQLISKSAISTKFE---AHARRAREIVGEMRNNLDVV 379

[Close]

BLAST of SMED30031809 vs. TrEMBL
Match: A0A3P6SYV7 (Dynamin-type G domain-containing protein OS=Litomosoides sigmodontis OX=42156 GN=NLS_LOCUS3882 PE=3 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 2.015e-16
Identity = 76/303 (25.08%), Postives = 140/303 (46.20%), Query Frame = -1

Query:  564 KRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIP-------IKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDI-IHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE------KEESNFNDEISKEKYQFRENAF----SQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFN 1415
            K  ++ IR   +R+T   VF+GRTS GKSS+IN  +   +LP G G  +   ++++ S   + F  V   D+ ++  I  L+ +       N ++        + VF+      ++  ++ I D+PG++   +F+S I   C +AD+ V++ ++ S     EK+   +  +K S  N  I+ + +D      ++  ++ + H    + +  +EL +  E E    IFF+S  E      KE    +D    E YQ+R   F    +QF   IS     T F     + +++ EI  ++ N  +
Sbjct:   59 KESIKTIRDMFMRDTMKVVFFGRTSNGKSSVINAMLHAKVLPQGMGHTTCCFLQVEGSPDDQKF--VLNEDSSERMNIEQLQRLGHAMSDSNVSLTEMGQDSLLHVFYPKSASRLLQNDVVIVDSPGVDLSPEFDSWIDKHCMDADVFVLVCNAESTLTQAEKSFFHRVSSKLSRPNIFILNNRWDASAAEVENMQQVREQHMTRFKQFLVSELKVCSEAEAANRIFFISAREMLDIRLKERGVIHDAYQVEGYQYRAMEFCNFETQFEQLISKSAISTKFE---AHARRAREIVGEMRNNLD 356

[Close]

BLAST of SMED30031809 vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 83.1889 bits (204), Expect = 2.368e-16
Identity = 58/233 (24.89%), Postives = 114/233 (48.93%), Query Frame = -1

Query:  744 LEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIE---NFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1427
            +E    +L +I+    R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   K +L  K   + ++  I  +  +A    ++   +    +KVF+   +  ++  ++ + D+PG +   Q +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ D++ K H +   N+   EL +    E   +IFF+S  E
Sbjct:   58 IESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYL--KTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDRCVNFLVEELKVVDREEAPNHIFFVSAKE 288

[Close]

BLAST of SMED30031809 vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 82.8037 bits (203), Expect = 3.163e-16
Identity = 58/233 (24.89%), Postives = 114/233 (48.93%), Query Frame = -1

Query:  744 LEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIE---NFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1427
            +E    +L +I+    R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   K +L  K   + ++  I  +  +A    ++   +    +KVF+   +  ++  ++ + D+PG +   Q +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ D++ K H +   N+   EL +    E   +IFF+S  E
Sbjct:   58 IESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYL--KTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDRCVNFLVEELKVVDREEAPNHIFFVSAKE 288

[Close]

BLAST of SMED30031809 vs. Ensembl Cavefish
Match: ENSAMXT00000043809.1 (mitofusin-1-like [Source:NCBI gene;Acc:103034819])

HSP 1 Score: 81.6481 bits (200), Expect = 7.830e-16
Identity = 80/337 (23.74%), Postives = 144/337 (42.73%), Query Frame = -1

Query:  462 LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCV---KENDTIKQTEIAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEI--FDDLFNEF------NGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKV 1433
            + ++   R+L+ I     R      F+GRTS GKS++IN  + E +LP+G G  +N  + ++ +   + FL     +E  +IK        L   +N   +    ++VF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D      ++ D + K H +   ++  +EL +    +    IFF+S  E                    A S   +R  G M ET       +  + +E   F+  F EF         F +      Q+ E +K+ M A+ NI S   KV
Sbjct:   56 MEIQSCSRKLEAIWEVLARRQMKVAFFGRTSNGKSTVINAMLRERVLPSGIGHTTNCFISVEGTDGDQAFLTTENSEERKSIKTVNQLAHALHMDRNL--DSGCLVRVFWPKTKCALLRDDLVLMDSPGTDVTSELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVSERISKPNIFILNNRWDASETEPEYLDGVRKQHMDRCVSFLVDELKVVSPDQAPNRIFFVSAKE--------------------ALSARIHRAQG-MPETGAALADGFQDRLQEFQSFERTFEEFISHSSVKTKFEQHTIRAWQITESLKTIMDAI-NITSAEKKV 368

[Close]

BLAST of SMED30031809 vs. Ensembl Cavefish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 78.9518 bits (193), Expect = 5.013e-15
Identity = 51/215 (23.72%), Postives = 107/215 (49.77%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R     VF+GRTS GKSS+IN  + + +LP+G G  +N  + ++ +   + FL  + ++  K  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ +E+ + H +   ++  +EL +    + +  IFF+S  E
Sbjct:   94 RRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNEAFLLTEGSEERKNVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMEEVRRQHMDRCSSFLVDELGVVDRAQASDRIFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. Ensembl Nematostella
Match: EDO42379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L1])

HSP 1 Score: 73.1738 bits (178), Expect = 1.191e-13
Identity = 51/219 (23.29%), Postives = 109/219 (49.77%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAK---QNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEKGQFESVILD-LCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQD---FDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R+     F+GRTS GKS+++N  + + ILP G G  +N  + +  S +   ++ + E+D  ++  +  L  IA    +  +++ ++ ++V++   +  ++++++ + D+PG++      + +D  C +AD+ V++ ++ S     EKN   K   K S  N  I+ + +D      D    + + K H     ++ S EL    + +    +FF+S  E
Sbjct:   93 RDQMKVAFFGRTSNGKSTVVNAMLQDRILPMGIGHTTNCFLSVNGSDSADPYILIPESD--ERRNVKTLGQIAHALFEEKLDHSSL-VQVYWPKSRCKMLSEDVVLVDSPGIDVSPDLDLWIDKHCLDADVFVLVCNAESTLMVTEKNFFHKVNQKLSKPNIFILNNRWDASAGEPDVEMMELVKKQHLQRNVDFLSKELKCVDKKQAEDRVFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. Ensembl Medaka
Match: ENSORLT00000009003.2 (pep primary_assembly:ASM223467v1:17:11595384:11602171:-1 gene:ENSORLG00000007178.2 transcript:ENSORLT00000009003.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 9.841e-18
Identity = 66/270 (24.44%), Postives = 126/270 (46.67%), Query Frame = -1

Query:  744 NILPIIAKLNDFVIILKCFASKWNLKSGDFSEIE---LNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQ-TEIAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEKG-QFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1535
            +I  I  +L DFV     F     L+  D   +E   L ++    +L  IR   LR      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   + +L  + ++  +  + +  L      +P  + +  +KVF+   +  ++  ++ + D+PG +   + +S I   C +AD+ V++ ++ S     EK    K   + S  N  I+++ +D      D+  E+ K H +    + + EL +    E    IFF+S  E
Sbjct:   18 SITSIFDQLLDFVKDGSAFVDA-ALQKDDMVAVEEQSLEMQSCATKLYTIRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDGDEAYLTSEASEERRSISTVNQLAHALHMDPTLDSSCLVKVFWPKSRCALLRNDLVLMDSPGTDVTLELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQEVRKQHLDRCVGFLAEELGVVGPNEAPGRIFFISAKE 286

[Close]

BLAST of SMED30031809 vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 82.0333 bits (201), Expect = 5.822e-16
Identity = 64/272 (23.53%), Postives = 134/272 (49.26%), Query Frame = -1

Query:  744 FENILPIIAKLNDFVIILKCFASKWNLKSGDF-SEIELNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIE---NFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1541
            FE +L  + + ++FV  +    +  N+ + D  SEI+   +    +L +I+    R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   +++L  + +D  ++  I  +  +A    ++   +    ++VF+   +  ++  ++ + D+PG +   Q +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   N  ++ +++ K H +   N+   EL +    +    IFF+S  E
Sbjct:   34 FEQLLNYVKETSEFVEDISGNTALENVATPDQKSEIQAYAD----KLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSD--EEKSIKTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKE 299

[Close]

BLAST of SMED30031809 vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 81.2629 bits (199), Expect = 1.061e-15
Identity = 66/280 (23.57%), Postives = 132/280 (47.14%), Query Frame = -1

Query:  744 FENILPIIAKLNDFVIILKCFASKWNLKSGDFSEIELNL--EDGKRELQ-------IIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIE---NFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1541
            FE +L  + + ++FV            + G F E   N+   D K E+Q       +I+    R      F+GRTS GKS++IN  + + +LP+G G  +N  + ++ +   +++L  + +D  ++  I  +  +A    ++   +    ++VF+   +  ++  ++ + D+PG +   Q +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   N  ++ +++ K H +   N+   EL +    +    IFF+S  E
Sbjct:   34 FEQLLNYVKETSEFV------------EGGRFPESLENVATPDQKSEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSD--EEKSIKTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKE 299

[Close]

BLAST of SMED30031809 vs. Ensembl Medaka
Match: mfn2 (mitofusin 2 [Source:NCBI gene;Acc:101170481])

HSP 1 Score: 79.337 bits (194), Expect = 3.782e-15
Identity = 52/215 (24.19%), Postives = 107/215 (49.77%), Query Frame = -1

Query:  744 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLE-KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDF-DEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFE 1379
            R     VF+GRTS GKS++IN  + + +LP+G G  +N  + ++ +  ++ FL  + ++  K  + +  L     Q+   +    + V +   +  ++  ++ + D+PG++   + +S I   C +AD+ V++ +S S     EK+   K   + S  N  I+ + +D   +  ++ DE+ + H +   N+   EL +    + +  IFF+S  E
Sbjct:   94 RRHMKVVFFGRTSNGKSTVINAMLCDKVLPSGIGHTTNCFLRVEGTDGSEGFLLTEGSEEKKSIKTVNQLAHALHQDQDLDAGSLVCVMWPKVKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMDEVRRQHMDRCSNFLVEELGVVDRAQASDRIFFVSAKE 308

[Close]

BLAST of SMED30031809 vs. Planmine SMEST
Match: SMESG000003238.1 (SMESG000003238.1)

HSP 1 Score: 970.304 bits (2507), Expect = 0.000e+0
Identity = 483/484 (99.79%), Postives = 484/484 (100.00%), Query Frame = -1

Query:   90 FENILPIIAKLNDFVIILKCFASKWNLKSGDFSEIELNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEKGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEIEKLKNKVKDLINSTECNDFCKNVLNEIYISKYFTYRPSISMVDDEDIMKNLLKIQHSDKIKTNMKTGMDSAMSVAAVA 1541
            FENILPIIAKLNDFVIILKCFASKWNLKSGDFSEIELNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGL+KGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEIEKLKNKVKDLINSTECNDFCKNVLNEIYISKYFTYRPSISMVDDEDIMKNLLKIQHSDKIKTNMKTGMDSAMSVAAVA
Sbjct:    9 FENILPIIAKLNDFVIILKCFASKWNLKSGDFSEIELNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLDKGQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILNIEKVINETVESEIEKLKNKVKDLINSTECNDFCKNVLNEIYISKYFTYRPSISMVDDEDIMKNLLKIQHSDKIKTNMKTGMDSAMSVAAVA 492

[Close]

BLAST of SMED30031809 vs. Planmine SMEST
Match: SMESG000003246.1 (SMESG000003246.1)

HSP 1 Score: 120.168 bits (300), Expect = 2.200e-28
Identity = 127/515 (24.66%), Postives = 241/515 (46.80%), Query Frame = -1

Query:  108 FVIILKCFASKWN--LKSGDFSEI-ELNLEDGKRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPS-QTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEKGQFESVILD-LCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENI---------AENYFSNELHIKKEYEENKNIFFLSGFEKEE--SNFNDEISKEKYQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFTEMMTETAQLVEEIKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKILN---------------------------------IEKVINETVESEIEKLKNKVKDLINST-ECNDFCKNVLNEIYISKYFTYRPSISMVDDEDIMKNLLKIQHSDKIKTNMKTGMDSAM 1502
            F  + K + + WN  +  G   +I E N+ D   +  +++ K   N K  V  G+TS+GKS++IN F+ EN+LPT FGS SN  +EIK S ++ + +L V      ++ +I  L +I      E     I +++   +  ++  ++ I D+PG++       ++D   R++D+ +++VSS++     E N+  + ++K +  N  IVY+F+D+         IC +H+++         A+    + L +     E+K IFF+S  E+    +N    IS  K+  R N F+   + +  +M E+   +K   L  +       FN+   +  EM  +  +L  ++K+E+  +E+    N+K+N EI   F      +L  GK+ +  K   ++LN                                  E+++++ +E+ I KL  ++ +L  S  + + F  N + +IY S+Y      +S  D   +  NL++I    KI + +  G+ +A+
Sbjct:   33 FFNLCKNYENDWNVGINVGILPDISERNICD---DFDLLKSKLNNNDKKFVVLGKTSSGKSTLINAFLTENLLPTEFGSTSNCFIEIKGSLESNRNYLVVNN----EEKDIDELGVINGSQ--EMMGSLITMYYDRAKCPLLGDDVIIIDSPGIDFDNLSVNLIDQYFRDSDVIILVVSSVTGITISEINLFKRLQSKLTKFNVAIVYNFWDV---------ICSSHKDVLIKPRYIQEAKKILCDILRLPDNEIESK-IFFISANERMAIFTNEVTAISAPKWDERNNEFASLFSYLQRKMSESADCKKFADLNNTYLEALANFNKCRCLIDEMKDKRIELAAKLKNELKKLED---FNSKINSEISAIFNDSYIDLLIKGKELL--KKNPQLLNKNNSNEEKYPLLERETIQDQTVYGERLRLSENEFEELLHQIIENSILKLTKRIIELSQSANDMDSFMLNKIFDIYFSQYLNLSEQLSHFDVGSLENNLIEINRKIKIASGVTIGLTAAV 523

[Close]

BLAST of SMED30031809 vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1)

HSP 1 Score: 116.701 bits (291), Expect = 3.739e-27
Identity = 82/279 (29.39%), Postives = 151/279 (54.12%), Query Frame = -1

Query:  558 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEK-GQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEE--SNFNDEISKEK-YQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGI 1379
            R  K CV +G+TS+GKSS+IN  + E ILPT  GS SN  V+IK S + K +  ++ N+ +K  E +  L  +  +  I++    + +F+  ++  ++ +N+ I DTPG++   +F++ ++   ++ ++ +++V+SLS    +EK  L K   KFS L+ LIV++ +D     ++ D + K +   A    ++EL    E   N+ IFFLS FE+    S+    + K+  ++ R  +F QF   +  E+   +  ++ + L +   +   LFN  N +
Sbjct:   62 RKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEY--IRINNEVKTIESLRELTSLLCEGHIKD-GSHVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNR-IFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELHSLILKLFNNSNAV 336

[Close]

BLAST of SMED30031809 vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1)

HSP 1 Score: 116.316 bits (290), Expect = 4.276e-27
Identity = 82/279 (29.39%), Postives = 152/279 (54.48%), Query Frame = -1

Query:  558 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEK-GQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEE--SNFNDEISKEK-YQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGI 1379
            R  K CV +G+TS+GKSS+IN  + E ILPT  GS SN  V+IK S + K ++ +  N+ +K  E +  L  +  +  I++ +  + +F+  ++  ++ +N+ I DTPG++   +F++ ++   ++ ++ +++V+SLS    +EK  L K   KFS L+ LIV++ +D     ++ D + K +   A    ++EL    E   N+ IFFLS FE+    S+    + K+  ++ R  +F QF   +  E+   +  ++ + L +   +   LFN  N +
Sbjct:   62 RKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELTSLLCEGHIKDGS-HVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNR-IFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELHSLILKLFNNSNAV 336

[Close]

BLAST of SMED30031809 vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1)

HSP 1 Score: 115.931 bits (289), Expect = 4.545e-27
Identity = 82/279 (29.39%), Postives = 151/279 (54.12%), Query Frame = -1

Query:  558 RNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSNRIVEIKPSQTTKTFLCVKENDTIKQTE-IAPLKLIAKQNPIENFAIPIKVFFGYKQEVVINQNMSIFDTPGLEK-GQFESVILDLCRNADITVMIVSSLSEFGTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENYFSNELHIKKEYEENKNIFFLSGFEKEE--SNFNDEISKEK-YQFRENAFSQFRNRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGI 1379
            R  K CV +G+TS+GKSS+IN  + E ILPT  GS SN  V+IK S + K ++ +  N+ +K  E +  L  +  +  I++    + +F+  ++  ++ +N+ I DTPG++   +F++ ++   ++ ++ +++V+SLS    +EK  L K   KFS L+ LIV++ +D     ++ D + K +   A    ++EL    E   N+ IFFLS FE+    S+    + K+  ++ R  +F QF   +  E+   +  ++ + L +   +   LFN  N +
Sbjct:   62 RKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELTSLLCEGHIKD-GSHVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNR-IFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELHSLILKLFNNSNAV 336

The following BLAST results are available for this feature:

BLAST of SMED30031809 vs. Ensembl Human
BLAST of SMED30031809 vs. Ensembl Celegans
BLAST of SMED30031809 vs. Ensembl Fly
BLAST of SMED30031809 vs. Ensembl Zebrafish
BLAST of SMED30031809 vs. Ensembl Xenopus
BLAST of SMED30031809 vs. Ensembl Mouse
BLAST of SMED30031809 vs. UniProt/SwissProt
BLAST of SMED30031809 vs. TrEMBL
BLAST of SMED30031809 vs. Ensembl Cavefish
BLAST of SMED30031809 vs. Ensembl Sea Lamprey
BLAST of SMED30031809 vs. Ensembl Yeast
BLAST of SMED30031809 vs. Ensembl Nematostella
BLAST of SMED30031809 vs. Ensembl Medaka
BLAST of SMED30031809 vs. Planmine SMEST

BLAST of SMED30031809 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MFN1	7.608e-16	23.61	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN1	2.780e-15	23.61	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN1	2.780e-15	23.61	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN2	1.491e-13	22.33	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]
MFN2	1.491e-13	22.33	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]

BLAST of SMED30031809 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
fzo-1	4.255e-17	28.14	Transmembrane GTPase fzo-1 [Source:UniProtKB/Swis...	[more]

BLAST of SMED30031809 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Marf	1.897e-14	25.23	gene:FBgn0029870 transcript:FBtr0070910	[more]
Marf	1.897e-14	25.23	gene:FBgn0029870 transcript:FBtr0070909	[more]
Marf	1.456e-13	24.34	gene:FBgn0029870 transcript:FBtr0343373	[more]
fzo	1.522e-9	22.35	gene:FBgn0011596 transcript:FBtr0084399	[more]

BLAST of SMED30031809 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MFN1	8.126e-18	22.97	mitofusin 1a [Source:NCBI gene;Acc:100329462]	[more]
mfn1b	1.941e-16	25.22	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	2.535e-16	25.22	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn2	4.714e-16	24.65	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]
mfn1b	9.171e-16	24.00	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]

BLAST of SMED30031809 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mfn1	9.842e-17	24.02	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.287e-16	24.02	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.317e-16	24.02	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.365e-16	24.02	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.485e-16	24.02	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]

BLAST of SMED30031809 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mfn2	7.190e-14	22.79	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	1.107e-13	22.79	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	1.107e-13	22.79	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	1.107e-13	22.79	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn1	1.508e-13	23.26	mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]	[more]

BLAST of SMED30031809 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q23424\|FZO1_CAEEL	5.412e-16	28.14	Transmembrane GTPase fzo-1 OS=Caenorhabditis elega...	[more]
sp\|Q8IWA4\|MFN1_HUMAN	1.335e-14	23.61	Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 S...	[more]
sp\|Q7YU24\|MARF_DROME	1.902e-13	25.23	Transmembrane GTPase Marf OS=Drosophila melanogast...	[more]
sp\|Q8R4Z9\|MFN1_RAT	4.082e-13	23.42	Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 ...	[more]
sp\|O95140\|MFN2_HUMAN	7.162e-13	22.33	Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 S...	[more]

BLAST of SMED30031809 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3S0ZZU2	8.169e-18	22.78	Dynamin-type G domain-containing protein (Fragment...	[more]
A0A437CEN8	4.859e-17	24.32	Dynamin-type G domain-containing protein OS=Oryzia...	[more]
A0A498SEU3	1.422e-16	26.33	Dynamin-type G domain-containing protein OS=Acanth...	[more]
A0A0R3QRG5	1.857e-16	25.25	Dynamin-type G domain-containing protein OS=Brugia...	[more]
A0A3P6SYV7	2.015e-16	25.08	Dynamin-type G domain-containing protein OS=Litomo...	[more]

BLAST of SMED30031809 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
mfn1b	2.368e-16	24.89	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
mfn1b	3.163e-16	24.89	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
ENSAMXT00000043809.1	7.830e-16	23.74	mitofusin-1-like [Source:NCBI gene;Acc:103034819]	[more]
mfn2	5.013e-15	23.72	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]

BLAST of SMED30031809 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30031809 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30031809 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO42379	1.191e-13	23.29	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30031809 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ENSORLT00000009003.2	9.841e-18	24.44	pep primary_assembly:ASM223467v1:17:11595384:11602...	[more]
mfn1b	5.822e-16	23.53	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
mfn1b	1.061e-15	23.57	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
mfn2	3.782e-15	24.19	mitofusin 2 [Source:NCBI gene;Acc:101170481]	[more]

BLAST of SMED30031809 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000003238.1	0.000e+0	99.79	SMESG000003238.1	[more]
SMESG000003246.1	2.200e-28	24.66	SMESG000003246.1	[more]
SMESG000002973.1	3.739e-27	29.39	SMESG000002973.1	[more]
SMESG000002973.1	4.276e-27	29.39	SMESG000002973.1	[more]
SMESG000002973.1	4.545e-27	29.39	SMESG000002973.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30031809 ID=SMED30031809|Name=SMED30031809|organism=Schmidtea mediterranea sexual|type=transcript|length=1637bp
TATATTTTTTCTTCAGACCTTTGGGACAGTGTGTGCTAATCTTATTTATA
AAATATAAAGATATAAATAATAACCGTGATTCCCCCAGTTGCCACAGCTG
CGACACTCATTGCACTATCCATTCCTGTTTTCATATTGGTTTTTATTTTA
TCTGAATGTTGAATTTTTAATAAGTTTTTCATAATATCTTCATCATCGAC
CATGCTTATACTTGGCCGATAGGTGAAATACTTGGATATATATATTTCAT
TGAGAACGTTCTTACAAAAGTCATTACATTCTGTGCTATTAATCAAGTCT
TTTACTTTATTTTTTAATTTCTCAATTTCACTTTCAACTGTTTCATTTAT
GACTTTTTCGATATTTAAAATTTTAGATTCATTTTTACAATCAACAGCTT
TTTTCCCATTTTTCAGCACACATTCAACAATAGATTTAAATGAGATGTCA
ATTTCTTTATTAACTTTTGTATTGAGAGATCCGATATTTTCCATGGCGCC
CATTTCAGATTTGATTTCCTCAACTAGTTGGGCTGTTTCCGTCATCATTT
CCGTAAATATCCCATTGAATTCATTAAATAAATCATCAAATATCTCTTCA
GATTTTTTCAAATAATTGAGTTTTCTTGTGAAATCCGTCTCCTCCATTTC
TCCCGAAATTCGATTTCTGAACTGAGAAAAAGCATTCTCCCTAAATTGAT
ACTTTTCCTTTGAAATTTCATCATTGAAGTTTGATTCTTCTTTTTCAAAT
CCAGAAAGAAAAAAAATATTTTTATTTTCTTCATATTCTTTCTTGATATG
GAGTTCGTTGGAAAAATAATTCTCTGCTATATTCTCATGATTTTTACAAA
TTTCGTCAAAGTCCTGTCCATTGTGGATAATATCATAAAAACTGTACACA
ATGAGAGCATTCAAATAAGAGAATTTGTTTTTACATTTCAGCAAAACATT
TTTCTCCAAAGTCCCAAATTCCGACAATGAGGAAACGATCATTACCGTTA
TGTCAGCATTCCGACACAAATCTAAAATCACTGATTCAAATTGACCTTTT
TCGAGTCCTGGAGTGTCAAATATGGACATATTCTGGTTAATGACCACTTC
TTGTTTATACCCAAAGAAAACCTTAATAGGAATTGCAAAATTTTCAATGG
GATTCTGTTTTGCAATTAGCTTTAAGGGAGCTATTTCTGTTTGCTTTATT
GTGTCATTTTCTTTTACACATAAAAATGTTTTAGTTGTTTGACTAGGTTT
GATTTCAACAATTCGATTGGAAACACTTCCAAAACCAGTTGGCAAAATAT
TTTCACCGATAAATCGGTTGATAATTGAGGACTTGCCAGTTGAAGTTCTT
CCGTAAAAAACGCAGGTCTTTGTATTTCTTAAACATTTGCACCGAATTAT
TTGCAATTCTCTTTTTCCATCTTCCAAATTTAATTCTATTTCACTAAAAT
CACCTGATTTCAAATTCCATTTTGAAGCAAAGCATTTCAAAATAATTACA
AAATCATTTAATTTTGCAATAATCGGTAAAATATTTTCGAAAATTTTGTT
TATTTCTATTTCCATATTAAATTTCTTTTCTTTTTAAATTTAGTTGAAAA
ATCTTAAATTGGTTTACAAAAAACTTTCAGCCAAAAC

protein sequence of SMED30031809-orf-1

>SMED30031809-orf-1 ID=SMED30031809-orf-1|Name=SMED30031809-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=508bp
MEIEINKIFENILPIIAKLNDFVIILKCFASKWNLKSGDFSEIELNLEDG
KRELQIIRCKCLRNTKTCVFYGRTSTGKSSIINRFIGENILPTGFGSVSN
RIVEIKPSQTTKTFLCVKENDTIKQTEIAPLKLIAKQNPIENFAIPIKVF
FGYKQEVVINQNMSIFDTPGLEKGQFESVILDLCRNADITVMIVSSLSEF
GTLEKNVLLKCKNKFSYLNALIVYSFYDIIHNGQDFDEICKNHENIAENY
FSNELHIKKEYEENKNIFFLSGFEKEESNFNDEISKEKYQFRENAFSQFR
NRISGEMEETDFTRKLNYLKKSEEIFDDLFNEFNGIFTEMMTETAQLVEE
IKSEMGAMENIGSLNTKVNKEIDISFKSIVECVLKNGKKAVDCKNESKIL
NIEKVINETVESEIEKLKNKVKDLINSTECNDFCKNVLNEIYISKYFTYR
PSISMVDDEDIMKNLLKIQHSDKIKTNMKTGMDSAMSVAAVATGGITVII
YIFIFYK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000418	head
PLANA:0000420	parapharyngeal region

Vocabulary: **INTERPRO**
Term	Definition
IPR027094	Mitofusin_fam
IPR027088	Mitofusin-1
IPR000082	SEA_dom
IPR022812	Dynamin_SF
IPR027417	P-loop_NTPase

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005741	mitochondrial outer membrane
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0008053	mitochondrial fusion

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 400..427
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 68..330 e-value: 1.1E-16 score: 63.1
None	No IPR available	TMHMM	TMhelix		coord: 484..506
IPR022812	Dynamin superfamily	PFAM	PF00350	Dynamin_N	coord: 69..206 e-value: 1.6E-14 score: 54.3
IPR027094	Mitofusin family	PANTHER	PTHR10465	TRANSMEMBRANE GTPASE FZO1	coord: 5..275
IPR027088	Mitofusin-1	PANTHER	PTHR10465:SF2	MITOFUSIN-1	coord: 5..275
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 63..243

Main menu

SMED30031809

Zeng et. al., 2018

▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

blazegraph-runner