Peptidase S1 domain-containing protein

Overview
NamePeptidase S1 domain-containing protein
Smed IDSMED30031804
Length (bp)875
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Peptidase S1 domain-containing protein (SMED30031804) t-SNE clustered cells

Violin plots show distribution of expression levels for Peptidase S1 domain-containing protein (SMED30031804) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Peptidase S1 domain-containing protein (SMED30031804) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Peptidase S1 domain-containing protein (SMED30031804) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031804

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30031804h1SMcG0015732 SmedASXL_012934SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30031804h1SMcG0015732 SmedASXL_012934SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30031804h1SMcG0015732 OX_Smed_1.0.18975ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: KLK13 (kallikrein related peptidase 13 [Source:HGNC Symbol;Acc:HGNC:6361])

HSP 1 Score: 133.65 bits (335), Expect = 9.472e-37
Identity = 83/250 (33.20%), Postives = 126/250 (50.40%), Query Frame = 1 
Query:   55 TSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYV-YGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            TSG+ +  G     H  P   ++ VQG   CGG L++   VLTAAHC+               +K+YLG++ L ++   E++ +V   I HP Y     ++ + +D+ L++    V  T   YI+   L  N+   PG  C V GWG+   P  +  + LQ A I + S  EC +++   +   + +CAG+      +C+GDSGGPL C     +    GIVS+G  PCGQ + P V+TRVS    WI +
Sbjct:   32 TSGF-LPGGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCL------------KEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLT--GYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPG-KITDNMLCAGTKEGGKDSCEGDSGGPLVC-----NRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRE 260
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: KLK15 (kallikrein related peptidase 15 [Source:HGNC Symbol;Acc:HGNC:20453])

HSP 1 Score: 121.324 bits (303), Expect = 2.731e-32
Identity = 83/262 (31.68%), Postives = 124/262 (47.33%), Query Frame = 1 
Query:   46 STITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWG--SMLPPGQDTS--------RFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            ST   G K++ G     H  P  V++  +G  +CG +L++ + VL+AAHC            +S  M++ LGE++L +  G E++   ++VI HP Y    A  + ND+ L++    V   + N      +       PG+ C V GWG  S   PG   S          L  A I+I+S + C + +   R   + VCAG+      +C+GDSGGPL C       I  GIVS+G VPC     P V+T+V     WI +
Sbjct:   13 STAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHC------------QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE---ARSHRNDIMLLRL---VQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPG-RLTNTMVCAGAEGRGAESCEGDSGGPLVCGG-----ILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRE 250
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: CTRL (chymotrypsin like [Source:HGNC Symbol;Acc:HGNC:2524])

HSP 1 Score: 120.553 bits (301), Expect = 7.183e-32
Identity = 84/249 (33.73%), Postives = 127/249 (51.00%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIK-VQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDL---NSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +I+NG  A++  +P  VS++   G H CGG+L++ + V+TAAHC       N++  + +   + LGEYD        ++  V++ I HPS+ S       NDV L+K     S  QY   +   + L   N     G  C   GWG +   G  T   LQ+ A+ +++ ++C R +       S +CAG      S+C+GDSGGPL C  G    + +GIVS+G   C     P V+TRVS+ + WINQ
Sbjct:   33 RIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC-------NVSPGRHF---VVLGEYDRSSNAEPLQVLSVSRAITHPSWNST---TMNNDVTLLKL---ASPAQYT-TRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQC-RQYWGSSITDSMICAGGAG--ASSCQGDSGGPLVCQKGNT-WVLIGIVSWGTKNC-NVRAPAVYTRVSKFSTWINQ 259
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: KLK15 (kallikrein related peptidase 15 [Source:HGNC Symbol;Acc:HGNC:20453])

HSP 1 Score: 118.627 bits (296), Expect = 2.744e-31
Identity = 81/257 (31.52%), Postives = 122/257 (47.47%), Query Frame = 1 
Query:   61 GWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWG--SMLPPGQDTS--------RFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            G K++ G     H  P  V++  +G  +CG +L++ + VL+AAHC            +S  M++ LGE++L +  G E++   ++VI HP Y    A  + ND+ L++    V   + N      +       PG+ C V GWG  S   PG   S          L  A I+I+S + C + +   R   + VCAG+      +C+GDSGGPL C       I  GIVS+G VPC     P V+T+V     WI +
Sbjct:   19 GDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHC------------QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE---ARSHRNDIMLLRL---VQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPG-RLTNTMVCAGAEGRGAESCEGDSGGPLVCGG-----ILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRE 251
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: KLK8 (kallikrein related peptidase 8 [Source:HGNC Symbol;Acc:HGNC:6369])

HSP 1 Score: 112.849 bits (281), Expect = 4.325e-29
Identity = 75/246 (30.49%), Postives = 111/246 (45.12%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVS-NTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            K++ G     H  P   ++       CGG L+ GN VLTAAHC            K     + LG++ L    G E+   V + I HP Y S     + +D+ L++     S  ++   I   +      T+PG +C V GWG++  P ++    L  A + I    +C   +   +     VCAGS S     C+GDSGGPL C DG       GI S+G  PCG+++ P V+T +     WI +
Sbjct:   32 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC------------KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLAD----HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPG-QITDGMVCAGS-SKGADTCQGDSGGPLVC-DGALQ----GITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-1 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q23528])

HSP 1 Score: 98.5969 bits (244), Expect = 7.371e-24
Identity = 79/253 (31.23%), Postives = 122/253 (48.22%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQ-GSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDR-CEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRI--FTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCT-DGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN 810
            ++I G+ +  H +P  V +  + G H CGG+L++ N VLTAAHC    R        SYS+++           G     +VT V IHP Y   F   Y  D A+++    V+ +         + L S+    +R C V GWGS +     ++  L++  + +LST  CS +  +    ++ S +CAG       +C+GDSGGPL C  DG  H    G+VS+G + C +  +P V+  V   + WIN   N
Sbjct:   57 RLIGGSESSPHSWPWTVQLLSRLGHHRCGGSLIDPNFVLTAAHCFAKDRR-----PTSYSVRVG------GHRSGSGSPHRVTAVSIHPWYNIGFPSSY--DFAIMRIHPPVNTSTTAR----PICLPSLPAVENRLCVVTGWGSTIEGSSLSAPTLREIHVPLLSTLFCSSLPNYIGRIHLPSMLCAGYSYGKIDSCQGDSGGPLMCARDG--HWELTGVVSWG-IGCARPGMPGVYGNVHSASTWINLEMN 289
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: svh-1 (HGF/MSP/plasminogen-like protein [Source:UniProtKB/TrEMBL;Acc:Q17800])

HSP 1 Score: 94.7449 bits (234), Expect = 1.895e-21
Identity = 69/251 (27.49%), Postives = 120/251 (47.81%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSI--KVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVAL--IKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC---SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            +++ G   +   +P   ++  K   +H CG ++L+   ++TAAHC            +  S ++ +G++D  Q  G E+IF + ++  +P Y      ++ +D+A+  I + G   N     I     D   +  PG +C V GWGSM   G   +  LQ A I I++  +C   S+I++++   A   CAG       +C+GDSGGP  C       +  G++S+G   C Q   P ++T V+    WI+
Sbjct:  712 RVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHCFEEDE-------RVSSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKD----IFSHDIAILEIPYPGIEFNEYAQPICLPSKDF--VYTPGRQCVVSGWGSM---GLRYAERLQAALIPIINRFDCVNSSQIYSSMSRSA--FCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGD-GCAQKKQPGIYTMVAPYLSWIS 943
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-3 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q94176])

HSP 1 Score: 68.1662 bits (165), Expect = 3.629e-13
Identity = 62/235 (26.38%), Postives = 103/235 (43.83%), Query Frame = 1 
Query:  145 CGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTS--------RFLQKAAINILSTSECSRI-----FTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPC----GQANVPTVFTRVSEVARWIN 798
            CG T+++   ++TAAHC   ++  +          +Y+ E         E+ F V +  IH  Y +  A    ND+AL++    +S      +     D + + K      V+G+G  L  G+D+S        + LQ  ++ I+S  +C +        +V+     +CAG+    T+   GDSGGPL        ++Q+GI SYG         Q   P V+TR+S+   WI 
Sbjct:   16 CGATVIDDFWLVTAAHCALQLQTRSF---------VYVRE----PKNNRERSFSVKEAYIHSGYNNQTA---DNDIALLRISSDLSKLGIKPVCLVHDD-SKLLKQYKNGVVIGYGLTL--GEDSSGEPKLINSQTLQSTSVPIISDDDCVKTWRFLSLLSVKITGYQICAGAYLHGTAP--GDSGGPLLIHKSNGEYVQIGITSYGADGLDGVIDQGKFPGVYTRISKYVPWIQ 229
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-3 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q94176])

HSP 1 Score: 68.1662 bits (165), Expect = 5.312e-13
Identity = 62/235 (26.38%), Postives = 103/235 (43.83%), Query Frame = 1 
Query:  145 CGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTS--------RFLQKAAINILSTSECSRI-----FTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPC----GQANVPTVFTRVSEVARWIN 798
            CG T+++   ++TAAHC   ++  +          +Y+ E         E+ F V +  IH  Y +  A    ND+AL++    +S      +     D + + K      V+G+G  L  G+D+S        + LQ  ++ I+S  +C +        +V+     +CAG+    T+   GDSGGPL        ++Q+GI SYG         Q   P V+TR+S+   WI 
Sbjct:   66 CGATVIDDFWLVTAAHCALQLQTRSF---------VYVRE----PKNNRERSFSVKEAYIHSGYNNQTA---DNDIALLRISSDLSKLGIKPVCLVHDD-SKLLKQYKNGVVIGYGLTL--GEDSSGEPKLINSQTLQSTSVPIISDDDCVKTWRFLSLLSVKITGYQICAGAYLHGTAP--GDSGGPLLIHKSNGEYVQIGITSYGADGLDGVIDQGKFPGVYTRISKYVPWIQ 279
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG11836 (gene:FBgn0039272 transcript:FBtr0309271)

HSP 1 Score: 116.701 bits (291), Expect = 1.404e-30
Identity = 84/257 (32.68%), Postives = 132/257 (51.36%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQ-VTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQ---------YNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC-SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQN 804
            +I+ G    +++YP M  I   G   CGG+LL  + VL+AAHCV  +R           +++  G++D       + I + VT VI H S+  D    Y ND+AL++    +S ++         YNY   G +             VVGWG     G+  S  + +  + I+S +EC ++ + + R  +S +CAG  S+ +  C+GDSGGPL  ++G ++ I VGIVS+G V CG+   P V++RVS+   WI  N
Sbjct:   44 RIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRK--------SKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPD---TYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGRIGT-----------VVGWGRTSEGGELPS-IVNQVKVPIMSITECRNQRYKSTRITSSMLCAGRPSMDS--CQGDSGGPLLLSNGVKYFI-VGIVSWG-VGCGREGYPGVYSRVSKFIPWIKSN 273
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG11836 (gene:FBgn0039272 transcript:FBtr0473579)

HSP 1 Score: 117.087 bits (292), Expect = 2.645e-30
Identity = 84/257 (32.68%), Postives = 132/257 (51.36%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQ-VTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQ---------YNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC-SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQN 804
            +I+ G    +++YP M  I   G   CGG+LL  + VL+AAHCV  +R           +++  G++D       + I + VT VI H S+  D    Y ND+AL++    +S ++         YNY   G +             VVGWG     G+  S  + +  + I+S +EC ++ + + R  +S +CAG  S+   +C+GDSGGPL  ++G ++ I VGIVS+G V CG+   P V++RVS+   WI  N
Sbjct:   96 RIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRK--------SKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPD---TYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGRIGT-----------VVGWGRTSEGGELPS-IVNQVKVPIMSITECRNQRYKSTRITSSMLCAGRPSM--DSCQGDSGGPLLLSNGVKYFI-VGIVSWG-VGCGREGYPGVYSRVSKFIPWIKSN 325
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG32808 (gene:FBgn0052808 transcript:FBtr0070295)

HSP 1 Score: 114.005 bits (284), Expect = 1.167e-29
Identity = 85/251 (33.86%), Postives = 120/251 (47.81%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIK--VQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVV-GWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN 810
            KI+NGT A   E+P +VS++    G HSCG TLLN   VLTAAHCV       L+        +  G   L +     ++ +V  + +HP Y  +  YV  ND+AL++    V+ ++  +++   L       PG+   V+ GWG +   G    + LQK  + + S +ECS       +  S +CAG        C GDSGGPL          QVGIVS+   PC +   P VFT VS    WI +  N
Sbjct:   29 KIVNGTTAGPGEFPFVVSLRRAKSGRHSCGATLLNPYWVLTAAHCVRGSSPEQLD--------LQYGSQMLAR--NSSQVARVAAIFVHPGYEPEDKYV--NDIALLQLAQSVALSK--FVQPVRLPEPRQVTPGNASAVLAGWG-LNATGGVVQQHLQKVKLQVFSDTECSERHQTYLH-DSQICAGLPEGGKGQCSGDSGGPLLLIG---SDTQVGIVSWSIKPCARPPFPGVFTEVSAYVDWIVETVN 260
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: l(2)k05911 (gene:FBgn0284244 transcript:FBtr0305556)

HSP 1 Score: 117.087 bits (292), Expect = 4.498e-29
Identity = 81/261 (31.03%), Postives = 135/261 (51.72%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKI-FQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-----------GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVR---YVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQN 804
            +I+ G  A  HE+P +  +   G   CGG+L+  + +LTAAHCV  M +W++      ++  +LG+Y++   + V+ +  ++ +++ H  +  +F+ ++ NDVA++     V  T+         ++  I  P           G    V GWGS+   G   S  LQK  I I + +EC+R +        + S +CAG    +  +C GDSGGP+   DG R + QVGIVS+G + CG+   P V+TRV+ +  WI +N
Sbjct:  399 RIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVARMTSWDV-----AALTAHLGDYNIGTDFEVQHVSRRIKRLVRHKGF--EFSTLH-NDVAILTLSEPVPFTR---------EIQPICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQPS-ILQKVDIPIWTNAECARKYGRAAPGGIIESMICAGQA--AKDSCSGDSGGPMVINDGGR-YTQVGIVSWG-IGCGKGQYPGVYTRVTSLLPWIYKN 637
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: tpr (gene:FBgn0034661 transcript:FBtr0071743)

HSP 1 Score: 114.005 bits (284), Expect = 6.332e-29
Identity = 82/253 (32.41%), Postives = 123/253 (48.62%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKI-FQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-------GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPL-FCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            +I+ G    +H+YP +  +   G   C  +LLN   +LTA+HCV+         F+   + + L E+D  +M  ++KI  +V +VI HP Y    A  Y ND+A+IK D  V   ++N +      L+ +  P       G+   V GWG+ L  G  TS  LQ+  + ILS  EC +     +   + +C G       +C+GDSGGPL     G R H   G+VS+G   C +A  P V+ RV+    WI 
Sbjct:  126 RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYG--------FRKERISVRLLEHD-RKMSHMQKIDRKVAEVITHPKYN---ARNYDNDIAIIKLDEPV---EFNEV------LHPVCMPTPGRSFKGENGIVTGWGA-LKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEG-CAKAGYPGVYARVNRYGTWIK 355
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:112285 (zgc:112285 [Source:ZFIN;Acc:ZDB-GENE-050913-132])

HSP 1 Score: 122.094 bits (305), Expect = 3.387e-32
Identity = 86/256 (33.59%), Postives = 125/256 (48.83%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQ--GS----HSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSIT-KPGDRCEVVGWGSMLPPGQDTS--RFLQKAAINILSTSEC-SRIFTNVRYVASNVCAG--SGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            +I++G  A  H +P  VS++V+  GS    H CGGTL++ N VLTAAHC    +        + S +I LG++ L +    E+ F V ++  H  +          D+AL+K    +  +  N+I+Y  L    I   PG  C V GWG      ++ S    L +A + I+    C  + F   R   S +CAG      + +AC+GDSGGPL C  GR      GIVS+G + C   N P+VFTR +    WI 
Sbjct:   58 RIVSGNEARPHSWPWQVSLQVRPRGSKHYVHVCGGTLIHKNWVLTAAHCFQKGK-----AEDASSWRIVLGKHQLKRSETAERFFPVKRIYRHEHFRYPAHSELDYDIALVKAATDIQPS--NFIRYACLPRKQINLNPGHYCWVTGWGDTRGGKENVSLAEALNQARLPIIDYKTCRQKKFWGDRVRDSMICAGFRDTEGTPAACQGDSGGPLLCQVGRDRWEVHGIVSFGPIGCTVENKPSVFTRTAAYIPWIE 306
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: cela1.6 (chymotrypsin like elastase family member 1, tandem duplicate 6 [Source:ZFIN;Acc:ZDB-GENE-040808-55])

HSP 1 Score: 119.398 bits (298), Expect = 9.980e-32
Identity = 86/252 (34.13%), Postives = 130/252 (51.59%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGS----HSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYN-YIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSR-IFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSY-GRVPCGQANVPTVFTRVSEVARWIN 798
            +++ G  A  + +P  +S++        H+CGGTL+  N VLTAAHCV + R W          ++ LGE+D+Y+  G E+   V+ V IHP++  +     G D+AL++     SN   N Y++ G L  +    P  + C + GWG +   G   S  L++A + ++  + CSR  +       + VCAG GSL  S C+GDSGGPL C    ++ +  G+ S+     C     PTVFTRVS    WIN
Sbjct:   29 RVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGTLIKQNFVLTAAHCVDTSRTW----------RVVLGEHDIYKQEGREQYMTVSNVYIHPNWNRNNV-AAGYDIALLRLS---SNASLNTYVQLGTLPPSGQVLPHNNACYITGWG-LTSTGGSLSAQLKQAYLPVVDYNTCSRGDWWGSTVKNTMVCAGGGSL--SGCQGDSGGPLNCQVSGQYVVH-GVTSFVSSSGCNAYQKPTVFTRVSAYISWIN 262
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: cela1.6 (chymotrypsin like elastase family member 1, tandem duplicate 6 [Source:ZFIN;Acc:ZDB-GENE-040808-55])

HSP 1 Score: 119.398 bits (298), Expect = 1.094e-31
Identity = 86/252 (34.13%), Postives = 130/252 (51.59%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGS----HSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYN-YIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSR-IFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSY-GRVPCGQANVPTVFTRVSEVARWIN 798
            +++ G  A  + +P  +S++        H+CGGTL+  N VLTAAHCV + R W          ++ LGE+D+Y+  G E+   V+ V IHP++  +     G D+AL++     SN   N Y++ G L  +    P  + C + GWG +   G   S  L++A + ++  + CSR  +       + VCAG GSL  S C+GDSGGPL C    ++ +  G+ S+     C     PTVFTRVS    WIN
Sbjct:   29 RVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGTLIKQNFVLTAAHCVDTSRTW----------RVVLGEHDIYKQEGREQYMTVSNVYIHPNWNRNNV-AAGYDIALLRLS---SNASLNTYVQLGTLPPSGQVLPHNNACYITGWG-LTSTGGSLSAQLKQAYLPVVDYNTCSRGDWWGSTVKNTMVCAGGGSL--SGCQGDSGGPLNCQVSGQYVVH-GVTSFVSSSGCNAYQKPTVFTRVSAYISWIN 262
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: si:ch73-182e20.4 (si:ch73-182e20.4 [Source:ZFIN;Acc:ZDB-GENE-131127-155])

HSP 1 Score: 119.013 bits (297), Expect = 1.977e-31
Identity = 90/262 (34.35%), Postives = 128/262 (48.85%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGEL-DLNSITKPGDRCEVVGWG------------------SMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWI 795
            +I+ G  +    +P MVS++  G+H CGG+L+N   VLTAAHCV   R+         +M +YLG++  Y     E    V+ +I HPSY S     Y ND+AL++    V  +  +YIK   L D  S   PG R    GWG                   + PPG      LQ+  + + S ++C+ I  + R   + +CAG+ S   +   GDSGGPL         +Q G+VS+G   C Q N+P VF RVSE  +WI
Sbjct:   15 RIVGGLNSTEGAWPWMVSLRYYGNHICGGSLINNEWVLTAAHCVNLTRS---------NMLVYLGKWRRYAADVNEITRTVSNIIPHPSYNST---TYDNDIALLQLSSTVHYS--DYIKPVCLADEQSNFPPGTRSWATGWGRIGVSGKGGIRGRTTVSVPLPPPG-----ILQEVKLKVYSNADCNSI-CHGRINPNMICAGTRSGGKATFSGDSGGPLVSKQCSV-WVQAGVVSHG-YGCAQPNLPEVFIRVSEYKQWI 254
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: ctrl (chymotrypsin-like [Source:ZFIN;Acc:ZDB-GENE-040912-147])

HSP 1 Score: 118.242 bits (295), Expect = 2.888e-31
Identity = 82/247 (33.20%), Postives = 124/247 (50.20%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIK-VQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +I+NG  A+   +P  VS++   G H CGG+L+N   V+TAAHC            ++    + LGE+D        ++  + K I HP Y S     + ND+ L+K       T  + I    L  +S + P G RC   GWG        + R LQ+ A+ +LS ++C + +   R   + +CAG+  +S+  C+GDSGGPL C      + QVGIVS+G   C     P V+ RVS + +WI+Q
Sbjct:   31 RIVNGENAVSGSWPWQVSLQQSNGFHFCGGSLINQYWVVTAAHC----------RVQAGYHYVILGEHDRGSSAESVQVKSIAKAITHPYYNSQN---FNNDITLLKLSSPAQLT--SRISPVCLAASSTSIPSGTRCVTTGWGKT--GSTSSPRILQQTALPLLSPAQCKQYWGQNRITDAMICAGASGVSS--CQGDSGGPLVCESSGAWY-QVGIVSWGTSDC-NVRTPAVYARVSYLRQWIDQ 256
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000015569.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:2816071:2829750:1 gene:ENSXETG00000010028.1 transcript:ENSXETT00000015569.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.168 bits (300), Expect = 3.231e-31
Identity = 95/305 (31.15%), Postives = 149/305 (48.85%), Query Frame = 1 
Query:    1 MIQNILLFLVLLISCSTITSGW-------KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWG------SMLPPGQDTSRFLQKAAINILSTSECSRIF-------TNVRYVASN-VCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN*ISFQ*FYLCLNI 849
            M+  I+  L+   + + I++G        +I+ G  A+  E+P  VSI  Q SH CGG+L++ N V++AAHC          ++K  +M++ LG + L  +     I +V +VI +P YT + +     D+A+++ +  V  T  +YI    + L +   P G  C V GWG      S+ PP       LQ+  + +++ S C  ++          + V  + +CAG       AC+GDSGGPL C  G  +    GIVS+G   C Q N P V+T+VS  + WINQ          YL LN+
Sbjct:    6 MMLRIISLLLAGFAVTAISTGCGQPAFSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHCF-------PRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGS---SGDIAMVEMESPV--TYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPP-----YPLQEVEVPLVNASSCDTMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKSG-NYWFLTGIVSWGDG-CAQPNRPGVYTKVSSFSSWINQ----------YLVLNV 281
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000030871.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:2823629:2829750:1 gene:ENSXETG00000010028.1 transcript:ENSXETT00000030871.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 119.783 bits (299), Expect = 4.534e-31
Identity = 90/276 (32.61%), Postives = 137/276 (49.64%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWG------SMLPPGQDTSRFLQKAAINILSTSECSRIF-------TNVRYVASN-VCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN*ISFQ*FYLCLNI 849
            +I+ G  A+  E+P  VSI  Q SH CGG+L++ N V++AAHC          ++K  +M++ LG + L  +     I +V +VI +P YT + +     D+A+++ +  V  T  +YI    + L +   P G  C V GWG      S+ PP       LQ+  + +++ S C  ++          + V  + +CAG       AC+GDSGGPL C  G  +    GIVS+G   C Q N P V+T+VS  + WINQ          YL LN+
Sbjct:   36 RIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHCF-------PRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGS---SGDIAMVEMESPV--TYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPP-----YPLQEVEVPLVNASSCDTMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKSG-NYWFLTGIVSWGD-GCAQPNRPGVYTKVSSFSSWINQ----------YLVLNV 282
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000015681.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:2721982:2727059:1 gene:ENSXETG00000009946.1 transcript:ENSXETT00000015681.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 117.857 bits (294), Expect = 1.196e-30
Identity = 85/254 (33.46%), Postives = 129/254 (50.79%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSM-KIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQ-DTSRFLQKAAINILSTSECSRIFT------NVRYVASN--VCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWI 795
            +I+ G  +    +P  V I  +    CGG+L+  N V++AAHC         N  K  S   +YLG Y +  + G E    + + I+HP+YT       G+D+AL++  G +  T  N+I+   L    +  P G +C V GWG++   G       LQ+ A+ ++   +C+ +F          YV SN  +CAG       +C+GDSGGPL C +  R ++ VGIVS+G V CGQ N P V+TR++    WI
Sbjct:   27 RIMGGQDSKAGMWPWQVMIYSEAFELCGGSLITNNWVVSAAHC--------FNRTKPPSFYTVYLGVYQISVLNGNEVAMPIKQFIVHPNYTVPEN---GSDIALVELSGDIIYT--NHIQPVCLPTGGVNLPTGLQCWVTGWGNIASNGDLPEPNTLQEVAVPLIGNQQCNALFQVPSPIDPKTYVISNDMLCAGFIDGGKDSCQGDSGGPLVCAEANRWYL-VGIVSFG-VGCGQPNRPGVYTRLNAYLDWI 265
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: trim36 (tripartite motif containing 36 [Source:Xenbase;Acc:XB-GENE-1017281])

HSP 1 Score: 122.094 bits (305), Expect = 1.829e-30
Identity = 86/258 (33.33%), Postives = 125/258 (48.45%), Query Frame = 1 
Query:   43 CSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMK----IYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASN--VCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            C     G +++ GT+A   E+P   S++V+G H CGGTL+    +LTAAHC          T +SY+      +YLG+  L +    E  F+V +++IHP Y  D    +  DVAL+  D  V  T  +               G  C V GWGS+   G  TS  LQK  I +++   C+ ++   RY  S   +CAG    S  AC+GDSG PL C        Q G+VS+G   CG      V++R++ + +WI 
Sbjct:  514 CGIQAVGIRLVGGTQAQEGEWPWQASLQVRGEHICGGTLVADQWILTAAHCF---------TPESYASPEVWTVYLGKVRLSRSTQKELAFKVIRLVIHPFYDED---SHDYDVALVLLDHLVPLTSPHVQPICLPSSTHHFPTGSSCWVTGWGSVKENG-PTSDVLQKVDIQLVAQDICTELY---RYQISPRMLCAGYRDGSKDACQGDSGSPLVCKTASGRWFQAGLVSWG-AGCGIPRYFGVYSRITRLVQWIE 754
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: trim36 (tripartite motif containing 36 [Source:Xenbase;Acc:XB-GENE-1017281])

HSP 1 Score: 120.553 bits (301), Expect = 3.338e-30
Identity = 86/258 (33.33%), Postives = 125/258 (48.45%), Query Frame = 1 
Query:   43 CSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMK----IYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASN--VCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            C     G +++ GT+A   E+P   S++V+G H CGGTL+    +LTAAHC          T +SY+      +YLG+  L +    E  F+V +++IHP Y  D    +  DVAL+  D  V  T  +               G  C V GWGS+   G  TS  LQK  I +++   C+ ++   RY  S   +CAG    S  AC+GDSG PL C        Q G+VS+G   CG      V++R++ + +WI 
Sbjct:  325 CGIQAVGIRLVGGTQAQEGEWPWQASLQVRGEHICGGTLVADQWILTAAHCF---------TPESYASPEVWTVYLGKVRLSRSTQKELAFKVIRLVIHPFYDED---SHDYDVALVLLDHLVPLTSPHVQPICLPSSTHHFPTGSSCWVTGWGSVKENG-PTSDVLQKVDIQLVAQDICTELY---RYQISPRMLCAGYRDGSKDACQGDSGSPLVCKTASGRWFQAGLVSWG-AGCGIPRYFGVYSRITRLVQWIE 565
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klk13 (kallikrein related-peptidase 13 [Source:MGI Symbol;Acc:MGI:3615275])

HSP 1 Score: 126.716 bits (317), Expect = 2.232e-34
Identity = 78/257 (30.35%), Postives = 131/257 (50.97%), Query Frame = 1 
Query:   67 KIINGTRA-----------IMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYV-YGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            KI+NGT             + H  P   ++ ++G   CGG L++   VLTAAHC            +     ++LG++ L ++   E+  +V + I HP Y     ++ + +D+ L++    V  +  ++++  +L  +     G  C V GWG+   P  +  + LQ A I + S  EC +++   +  A+ +CAG+      +C+GDSGGPL C +G+ +    GI+S+G  PCGQ N P V+TRVS+  RWI +
Sbjct:   25 KILNGTNGTSGFLPGGYTCLPHSQPWQAALLIRGRLLCGGVLVHPKWVLTAAHC------------RKDGYTVHLGKHALGRVENGEQAMEVVRSIPHPEYQVTPTHLNHDHDIMLLELKSPVQLS--SHVRTLKLSADDCLPTGTCCRVSGWGTTTSPQVNYPKTLQCANIELRSDEECRQVYPG-KITANMLCAGTKEGGKDSCEGDSGGPLIC-NGKLY----GIISWGDFPCGQPNRPGVYTRVSKYLRWIRE 261
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Gzmm (granzyme M (lymphocyte met-ase 1) [Source:MGI Symbol;Acc:MGI:99549])

HSP 1 Score: 122.479 bits (306), Expect = 8.246e-33
Identity = 84/249 (33.73%), Postives = 123/249 (49.40%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP--GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC--SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +II G  A+ H  P M S++   SH CGG L++   VLTAAHC+         +    ++K+ LG ++L+ +      F + + I HP Y     + Y ND+AL+K D  V  ++   +K   L     +KP  G  C   GWG M   G   +R LQ+  + +L T  C  SR +  V  + S +C  +GS S + CKGDSGGPL C  G+      GI+S+    C     P V T V+  + WI +
Sbjct:   26 QIIGGREAVPHSRPYMASLQKAKSHVCGGVLVHRKWVLTAAHCL---------SEPLQNLKLVLGLHNLHDLQDPGLTFYIREAIKHPGYN----HKYENDLALLKLDRRVQPSK--NVKPLALPRKPRSKPAEGTWCSTAGWG-MTHQGGPRARALQELDLRVLDTQMCNNSRFWNGV-LIDSMLCLKAGSKSQAPCKGDSGGPLVCGKGQVD----GILSFSSKTCTDIFKPPVATAVAPYSSWIRK 253
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klk15 (kallikrein related-peptidase 15 [Source:MGI Symbol;Acc:MGI:2447533])

HSP 1 Score: 119.783 bits (299), Expect = 6.976e-32
Identity = 86/280 (30.71%), Postives = 135/280 (48.21%), Query Frame = 1 
Query:   13 ILLFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP------GDRCEVVGWGSMLP--PGQDTSR--------FLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQN 804
            +LL  VLL+S +    G K++ G   + H  P  V++  +G  +CG  L++   VLTAAHC            ++  M++ LGE++L +  G E++  V+++I HP Y    A  + +D+ L++       T Y         +  +  P      G+ C V GWG +    PG   S+         L  A I+I+S + C++ +   R + + VCAG     T +C+GDSGGPL C    +     GIVS+G VPC     P V+T+V     WI +N
Sbjct:    3 LLLAFVLLVSAAQ--DGDKVLEGEECVPHSQPWQVALFERGRFNCGAFLISPRWVLTAAHC------------QTRFMRVRLGEHNLRKFDGPEQLRSVSRIIPHPGYE---ARTHRHDIMLLRLFKPARLTAY---------VRPVALPRRCPLIGEDCVVSGWGLLSDNNPGATGSQKSHVRLPDTLHCANISIISEASCNKDYPG-RVLPTMVCAGVEGGGTDSCEGDSGGPLVCGGALQ-----GIVSWGDVPCDTTTKPGVYTKVCSYLEWIWEN 250
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klk6 (kallikrein related-peptidase 6 [Source:MGI Symbol;Acc:MGI:1343166])

HSP 1 Score: 118.627 bits (296), Expect = 1.649e-31
Identity = 76/272 (27.94%), Postives = 125/272 (45.96%), Query Frame = 1 
Query:    1 MIQNILLFLVLLISCSTITSGW-----KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDL-NSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            M   +L   +L +      S W     K+++G   +   +P   ++   G   CGG L++   VLTAAHC            K  ++++ LG+++L Q    ++   V + I+HP Y  +    + ND+ ++     V  ++    K   L L N  ++    C+++GWG M     D    +Q A ++++   +C R +   +   S VCAG       +C+GDSGGPL C    R     G+VS+G +PCG    P V+T V    RWI 
Sbjct:    1 MPMKMLTMKMLALCLVLAKSAWSEEQEKVVHGGPCLKDSHPFQAALYTSGHLLCGGVLIDPQWVLTAAHC------------KKPNLQVILGKHNLRQTETFQRQISVDRTIVHPRYNPE---THDNDIMMVHLKNPVKFSK----KIQPLPLKNDCSEENPNCQILGWGKM--ENGDFPDTIQCADVHLVPREQCERAYPG-KITQSMVCAGDMKEGNDSCQGDSGGPLVCGGRLR-----GLVSWGDMPCGSKEKPGVYTDVCTHIRWIQ 245
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klk6 (kallikrein related-peptidase 6 [Source:MGI Symbol;Acc:MGI:1343166])

HSP 1 Score: 118.627 bits (296), Expect = 1.649e-31
Identity = 76/272 (27.94%), Postives = 125/272 (45.96%), Query Frame = 1 
Query:    1 MIQNILLFLVLLISCSTITSGW-----KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDL-NSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            M   +L   +L +      S W     K+++G   +   +P   ++   G   CGG L++   VLTAAHC            K  ++++ LG+++L Q    ++   V + I+HP Y  +    + ND+ ++     V  ++    K   L L N  ++    C+++GWG M     D    +Q A ++++   +C R +   +   S VCAG       +C+GDSGGPL C    R     G+VS+G +PCG    P V+T V    RWI 
Sbjct:    1 MPMKMLTMKMLALCLVLAKSAWSEEQEKVVHGGPCLKDSHPFQAALYTSGHLLCGGVLIDPQWVLTAAHC------------KKPNLQVILGKHNLRQTETFQRQISVDRTIVHPRYNPE---THDNDIMMVHLKNPVKFSK----KIQPLPLKNDCSEENPNCQILGWGKM--ENGDFPDTIQCADVHLVPREQCERAYPG-KITQSMVCAGDMKEGNDSCQGDSGGPLVCGGRLR-----GLVSWGDMPCGSKEKPGVYTDVCTHIRWIQ 245
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UKR3|KLK13_HUMAN (Kallikrein-13 OS=Homo sapiens OX=9606 GN=KLK13 PE=2 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 4.549e-36
Identity = 83/250 (33.20%), Postives = 126/250 (50.40%), Query Frame = 1 
Query:   55 TSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYV-YGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            TSG+ +  G     H  P   ++ VQG   CGG L++   VLTAAHC+               +K+YLG++ L ++   E++ +V   I HP Y     ++ + +D+ L++    V  T   YI+   L  N+   PG  C V GWG+   P  +  + LQ A I + S  EC +++   +   + +CAG+      +C+GDSGGPL C     +    GIVS+G  PCGQ + P V+TRVS    WI +
Sbjct:   32 TSGF-LPGGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCL------------KEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLT--GYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPG-KITDNMLCAGTKEGGKDSCEGDSGGPLVC-----NRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRE 260
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q06605|GRZ1_RAT (Granzyme-like protein 1 OS=Rattus norvegicus OX=10116 PE=2 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 7.363e-33
Identity = 82/260 (31.54%), Postives = 120/260 (46.15%), Query Frame = 1 
Query:   37 ISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHS----CGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDL-NSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +S +  T   +II G  A  H  P M  ++ +   S    CGG L+  + VLTAAHC  S  N            + LG +++ +    +++  V K+I HP+Y    A    ND+ L+K       T+   +K   L   N   KPGD C V GWG + P G+   + LQ+  + +    EC     N    A+ +CAG   +  ++ +GDSGGPL C       +  GIVSYGR      + P  FT+VS    WI +
Sbjct:   10 VSLAPTTEAAEIIGGHEADPHSRPYMAYLQYKNEDSRDTICGGFLIREDFVLTAAHCSGSKIN------------VTLGAHNIKEQEKTQQVIPVVKIIPHPAYN---AKTISNDIMLLKLKSKAKRTRA--VKTLSLPRSNFKVKPGDVCYVAGWGKLGPMGKFPDK-LQEVELTVQEDQECETYLKNAYDKANQICAGDPKIKCASFQGDSGGPLVC-----KKVAAGIVSYGR---KDGSTPRAFTKVSTFLSWIEE 243
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P80646|CTRB_GADMO (Chymotrypsin B OS=Gadus morhua OX=8049 PE=1 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 2.120e-32
Identity = 83/247 (33.60%), Postives = 127/247 (51.42%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIK-VQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKF-DGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +I+NG  A+ H +P  VS++   G H CGG+L+N N V+TAAHC       N+ T+     ++ +GE+D      ++ I + + V  HP + S       ND++LIK     V  T  + +  GE   + +  PG +C   GWG        T   LQ+AA+ ++S  ECS+ + N       +CAG+     ++C GDSGGPL C       + VGIVS+G   C     P V+ RV+E+  W++Q
Sbjct:   15 RIVNGEEAVPHSWPWQVSLQQSNGFHFCGGSLINENWVVTAAHC-------NVRTYH----RVIVGEHDKASDENIQ-ILKPSMVFTHPKWDS---RTINNDISLIKLASPAVLGTNVSPVCLGES--SDVFAPGMKCVTSGWGLTRYNAPGTPNKLQQAALPLMSNEECSQTWGNNMISDVMICAGAA--GATSCMGDSGGPLVCQKDNVWTL-VGIVSWGSSRC-SVTTPAVYARVTELRGWVDQ 240
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P18291|GRAB_RAT (Granzyme B OS=Rattus norvegicus OX=10116 GN=Gzmb PE=1 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 6.835e-32
Identity = 80/254 (31.50%), Postives = 120/254 (47.24%), Query Frame = 1 
Query:   55 TSGWKIINGTRAIMHEYPQMVSIKV----QGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSIT-KPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            T   +II G  A  H  P M  +++     GS  CGG L+  + VLTAAHC  S  N            + LG +++ +   +++I  V K+I HP+Y S       ND+ L+K       +  + +K   L   ++  KPGD C V GWG + P G+  S  LQ+  + +    +C     N    A+ +CAG   +  ++ +GDSGGPL C       +  GIVSYG+      + P  FT+VS    WI +
Sbjct:   16 TEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIN------------VTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSK---TISNDIMLLKLKSKAKRS--SAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVC-----KKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKK 243
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q03238|GRAM_RAT (Granzyme M (Fragment) OS=Rattus norvegicus OX=10116 GN=Gzmm PE=1 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 3.100e-31
Identity = 84/249 (33.73%), Postives = 119/249 (47.79%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP--GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC--SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +II G  A+ H  P MVS++   SH CGG L++   VLTAAHC+         +     +K+  G + L+        F + + I HP Y       Y ND+AL+K DG V  ++   +K   L      KP  G RC   GWG     GQ  ++ LQ+  + +L T  C  SR +  V    S +C  +G+   + CKGDSGGPL C  G+      GI+S+    C     PTV T V+  + WI +
Sbjct:   20 QIIGGREAVPHSRPYMVSLQNTKSHMCGGVLVHQKWVLTAAHCL---------SEPLQQLKLVFGLHSLHDPQDPGLTFYIKQAIKHPGYN----LKYENDLALLKLDGRVKPSK--NVKPLALPRKPRDKPAEGSRCSTAGWGITHQRGQ-LAKSLQELDLRLLDTRMCNNSRFWNGV-LTDSMLCLKAGAKGQAPCKGDSGGPLVCGKGKVD----GILSFSSKNCTDIFKPTVATAVAPYSSWIRK 247
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: H2DRI7 (Trypsin-like serine protease OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 343.969 bits (881), Expect = 5.358e-117
Identity = 157/202 (77.72%), Postives = 179/202 (88.61%), Query Frame = 1 
Query:  205 MRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN 810
            M++WNLNTFK Y M++YL EYDLY+MYGVEKIFQVTK IIHPSY  ++AY+ GNDVALIKFDG++SN QY+YI Y ELD+N+I KPGDRCEVVGWGSMLPPGQD SRFLQKAAINI+S SEC RIF+NV  V SN+CAGSG LSTS+C+GDSGGPLFCTDG+RHHIQVGIVSYG VPCGQ N+P+V+TRVSEVA WI  NAN
Sbjct:    1 MKSWNLNTFKYYQMEVYLAEYDLYRMYGVEKIFQVTKTIIHPSYRHEYAYLEGNDVALIKFDGFISNGQYDYIHYNELDVNAIFKPGDRCEVVGWGSMLPPGQDISRFLQKAAINIISNSECGRIFSNVADVRSNICAGSGRLSTSSCRGDSGGPLFCTDGKRHHIQVGIVSYGTVPCGQPNIPSVYTRVSEVAGWIKANAN 202
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A1I8GT16 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010631g1 PE=3 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 3.280e-52
Identity = 104/268 (38.81%), Postives = 161/268 (60.07%), Query Frame = 1 
Query:   16 LLFLVLLISCSTITSGWK--IINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDL-YQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP--GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCT-DGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            + FLVL  +C ++ + +   II+G  A   ++P +VS++  G+H CGGTL +  TV+TAAHC +     N  TF    + +  GE DL        + ++V++VIIHP Y S + YV G+D+A++K     ++     IK G+ +   +  P  G  C+V GWG++ P G+          ++ ++ ++C+R+F  V      VCAG G+ +T+AC+GDSGGPL+CT +G+    QVGIVSYGRVPCGQ  +PTV+TRV+   R+I+Q
Sbjct:    1 MKFLVLF-ACLSVANAYDRLIIDGVEASTGQHPDLVSLQRNGNHFCGGTLYDKRTVVTAAHCFYG----NSGTF---GLAVVAGENDLTLSNSANRRSYRVSRVIIHPDYRSSYHYVQGDDIAILKLSS-DADLGTATIKAGDFEDAGVDIPPAGSSCKVAGWGAIDPSGRYAHTRKMIGGVSSITNNDCARVFNRVLGNTKQVCAGGGT-TTNACRGDSGGPLYCTYNGKTR--QVGIVSYGRVPCGQVGIPTVYTRVATYRRFIDQ 256
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A1I8JAW5 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007344g1 PE=3 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 4.682e-52
Identity = 104/268 (38.81%), Postives = 160/268 (59.70%), Query Frame = 1 
Query:   16 LLFLVLLISCSTITSGWK--IINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDL-YQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP--GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCT-DGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            + FLVL  +C ++ + +   II+G  A   ++P +VS++  G+H CGGTL +  TV+TAAHC +     N  TF    + +  GE DL        + ++V++VIIHP Y S + YV G+D+A++K     ++     IK G+ +   +  P  G  C+V GWG++ P G+          ++ ++ ++C+R+F  V      VCAG G  +T+AC+GDSGGPL+CT +G+    QVGIVSYGRVPCGQ  +PTV+TRV+   R+I+Q
Sbjct:    1 MKFLVLF-ACLSVANAYDRLIIDGVEASTGQHPDLVSLQRNGNHFCGGTLYDKRTVVTAAHCFYG----NSGTF---GLAVVAGENDLTLSNSANRRSYRVSRVIIHPDYRSSYHYVQGDDIAILKLSS-DADLGTATIKAGDFEDAGVDIPPEGSSCKVAGWGAIDPSGRYAHTRKMIGGVSSITNNDCARVFNRVLGNTKQVCAG-GDTTTNACRGDSGGPLYCTYNGKTR--QVGIVSYGRVPCGQVGIPTVYTRVATYRRFIDQ 256
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A1I8JHD8 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 149.443 bits (376), Expect = 3.302e-40
Identity = 98/268 (36.57%), Postives = 149/268 (55.60%), Query Frame = 1 
Query:   16 LLFLVLLISCSTITSGWK--IINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDL-YQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP--GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCT-DGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            + FLVL  +C ++ + +   II+G  A   ++P +VS++  G+H CGGTL +  TV+TAAHC +     N  TF    + +  GE DL        + ++V++VIIHP Y S + YV G+D+A++K     ++     IK G+ +   +  P  G  C+V GWG++ P G+                      + + R +   V    G  +T+AC+GDSGGPL+CT +G+    QVGIVSYGRVPCGQ  +PTV+TRV+   R+I+Q
Sbjct:    1 MKFLVLF-ACLSVANAYDRLIIDGVEASTGQHPDLVSLQRNGNHFCGGTLYDKRTVVTAAHCFYG----NSGTF---GLAVVAGENDLTLSNSANRRSYRVSRVIIHPDYRSSYHYVQGDDIAILKLSS-DADLGTATIKAGDFEDAGVDIPPAGSSCKVAGWGAIDPSGR----------------------YAHTRKMIGGVR--GGGTTTNACRGDSGGPLYCTYNGKTR--QVGIVSYGRVPCGQVGIPTVYTRVATYRRFIDQ 233
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: U5EP40 (Putative trypsin-like serine protease OS=Corethrella appendiculata OX=1370023 PE=2 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 1.192e-38
Identity = 99/278 (35.61%), Postives = 145/278 (52.16%), Query Frame = 1 
Query:   25 LVLLISCSTITSGW---------KIINGTRAIMHEYPQMVSIK----------VQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKF-DGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSM-LPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWI 795
            L+L+IS + ITSG          KI+ G+ A  ++YP  +S++           +  H CGG+++N N +LTAAHC    +  NL+ F    +++  GE+ L      E+  QV + I+H SY      V  ND+A+IK  + +V N     I + E D    + P     + GWGSM +    +    LQ   + I+   ECS ++   +  ASNVCAG  + S S CKGDSGGPL  TDG  + +Q+G+VS+G  PCG  + P +F RVS    WI
Sbjct:    9 LILVISLA-ITSGLSLYSLEADHKIVGGSNAEPNQYPYQISLQWNFNETVANPRRPFHFCGGSVINANWILTAAHC----KVANLSEFGF--IEVVAGEHHLAFNDTTEQRRQVDRFILHESYGGG---VGPNDIAVIKVNESFVLNENVTRINFPERD----SIPSGNATLTGWGSMSITERPNAPNILQTVRLPIIEYEECSNLWNTTQLAASNVCAGELNGSKSGCKGDSGGPLVQTDGDLNVVQIGVVSWGSFPCGAEDKPGIFVRVSHFVNWI 272
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000043830.1 (elastase-1-like [Source:NCBI gene;Acc:103036513])

HSP 1 Score: 123.635 bits (309), Expect = 2.840e-33
Identity = 91/227 (40.09%), Postives = 123/227 (54.19%), Query Frame = 1 
Query:  136 SHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC-SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFC-TDGR-RHHIQVGIVSYGRVPCGQANV---PTVFTRVSEVARWI 795
            +H CGG+L++   V+TAAHC+  M+       + Y  ++ LG+YDLY+  G E+   V+++I+HP +T D   V GND+AL+K    V    Y  I          T P G  C + GWG +L  G  T   LQ+A I ++  S C S  + +     + VCAG G   TS C+GDSGGPL C TDG  R H   G+VS+G  P    N+   PTVFTRVS    WI
Sbjct:   61 AHICGGSLISSLYVMTAAHCILDMQ------LRFY--RVVLGDYDLYKYEGGEQPRSVSRIIMHPGWTGDL--VNGNDIALLKLSSPVYGNSYTEIA--NFPYPDQTLPNGFTCYITGWG-LLATGGTTPDILQEAPIPVVEHSVCASPGWWSTAVKKTMVCAG-GDGKTSGCQGDSGGPLNCYTDGAWRVH---GVVSFG--PASNCNIYTKPTVFTRVSSFMDWI 268
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000048530.1 (pep primary_assembly:Astyanax_mexicanus-2.0:13:20283923:20290642:1 gene:ENSAMXG00000040955.1 transcript:ENSAMXT00000048530.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 121.709 bits (304), Expect = 1.103e-32
Identity = 82/268 (30.60%), Postives = 134/268 (50.00%), Query Frame = 1 
Query:    4 IQNILLFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQD--TSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            I+ IL+F+    +C       +++ G  A+  E+P   S++V G H CGG L+    V++AAHC +  R ++ + +      +YLG+  L      E+  +++ + IH  Y  D  + Y  D+AL++ D  VS              + + +PG  C V GWG+M   G+    S  LQK  + ++S   C R +  +      +CAG  S    AC+GDSGGPL C +        G+VS+GR  CG+ +   V+TR++ ++ WI Q
Sbjct:    7 IEIILIFVDCSHNCGLRHFTTRVVGGADAVEGEWPWQASLQVSGRHICGGALIASQWVVSAAHCFYDDRLYSPSVW-----TVYLGKLRLRGTSQTEEALRLSHIHIH-QYYDDENHDY--DLALLRLDRPVSAGTLAQPACLPSHTHQL-EPGLLCWVTGWGAMKEGGEKRGPSNVLQKVDVRLVSEEACVRSYGYI-ITPRMLCAGYRSGGKDACQGDSGGPLVCQEPSGRWFLAGVVSWGR-GCGRPDYYGVYTRITRLSDWIKQ 263
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000014374.2 (chymotrypsinogen A-like [Source:NCBI gene;Acc:103033709])

HSP 1 Score: 120.939 bits (302), Expect = 2.078e-32
Identity = 89/249 (35.74%), Postives = 128/249 (51.41%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIK-VQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP---GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +I+NG  A+ H +P  VS++   G H CGG+LLN N VLTAAHC   +R          S  + LGE+D        +  ++ KVI HPSY S+      NDV LIK     S  Q N  +   + L + +     G +C   GWG       +T   LQ+ A+ +L+ S C R + +    +  VCAG+    +S+C GDSGGPL C  G   ++ VG+VS+G   C  ++ P V+ RV+    WI+Q
Sbjct:   33 RIVNGEEAVPHSWPWQVSLQDSTGWHFCGGSLLNQNWVLTAAHC--GVRT---------SHYVILGEHDRSSNAEAIQTLRIGKVIQHPSYNSN---TINNDVTLIKL---ASTAQLN-TRVSPVCLPASSDDYAGGLKCVTTGWGLTRYNAANTPPRLQQTALPLLTNSNCQRYWGS-SITSVMVCAGAA--GSSSCMGDSGGPLVCQKGGVWNL-VGVVSWGSSTCSTSS-PGVYARVTSFRSWIDQ 258
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000014359.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:20902992:20905615:-1 gene:ENSAMXG00000013952.2 transcript:ENSAMXT00000014359.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 117.472 bits (293), Expect = 9.678e-31
Identity = 86/250 (34.40%), Postives = 129/250 (51.60%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIK-VQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP---GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIF-TNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +I+NG  A+ H +P  VS++   G H CGG+L+N N V+TAAHC   +R          S  + LGE+D        +  ++ KVI HPSY S+      ND+ L+K     S  Q N  +   + L + +     G +C   GWG       +T   LQ+ A+ +L+ S C R + T++  V   +CAG+     S+C GDSGGPL C  G   ++ VG+VS+G   C  ++ P V+ RV+    WI+Q
Sbjct:   61 RIVNGEEAVPHSWPWQVSLQDSTGWHFCGGSLVNQNWVVTAAHC--GVRT---------SHYVILGEHDRSSNAEAIQTLRIGKVIQHPSYNSN---TINNDITLVKL---ASTAQLN-TRVSPVCLPASSDDYAGGLKCVTTGWGLTRYNAANTPPRLQQTALPLLTNSNCQRYWGTSITSVM--ICAGAA--GASSCMGDSGGPLVCQKGGVWNL-VGVVSWGSSTCSTSS-PGVYARVTSFRSWIDQ 286
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: si:dkey-32n7.9 (chymotrypsin-like protease CTRL-1 [Source:NCBI gene;Acc:103029386])

HSP 1 Score: 117.857 bits (294), Expect = 1.071e-30
Identity = 86/252 (34.13%), Postives = 125/252 (49.60%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSM--RNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSIT-KPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECS---RIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQN 804
            +I+ G  A    +P  VS+  Q  H CGGTL++   VLTAAHC+ S+   NW L          YLG  +       E    V ++I+HPSY +    ++ NDV L++    V+ +  +YI+   L  NS T      C   GWG +       S  LQ+  + ++  S+C+   ++  +    A  +CAGS    T  C+GDSGGPL C  G    +Q G+ SYG + C  A +P V+ RVSE   WI +N
Sbjct:   36 RIVGGANAQAGNWPWQVSMHHQDQHICGGTLIHQEWVLTAAHCILSLDTSNWML----------YLGRENQSTANPNEVSRGVQEIIMHPSYNNT---LFNNDVTLMRLSSPVNFS--DYIRPICLASNSSTFYSNTTCWSTGWGLLRHNESLASETLQEVEVPVVGNSQCACNYQVAKDANITAQMICAGSAGKGT--CQGDSGGPLQCKQGSV-WVQAGVTSYG-ISCA-AGIPEVYARVSEFQSWITEN 267
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008289.1 (pep scaffold:Pmarinus_7.0:GL480450:20964:30734:1 gene:ENSPMAG00000007473.1 transcript:ENSPMAT00000008289.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 111.309 bits (277), Expect = 1.466e-29
Identity = 73/248 (29.44%), Postives = 117/248 (47.18%), Query Frame = 1 
Query:   70 IINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYV---SNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC-SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            I+ G+    H  P   S++  G H CG  L+  N V+T+AHC  + +N          +K+ LG++ + +  G EK F V++V+ H  + +       NDV L+K    V   +N Q   ++   L       PG  C V GWG++       S  L+   + I+S + C S ++       + +CAG       AC+GDSGGPL C +  +     G+VS+G + C +     ++T VS +  WIN 
Sbjct:   26 IVGGSEVAPHAIPSQASLRYNGVHICGAALIRTNWVITSAHCYKAAQN----------LKVVLGDHSMSKADGTEKTFSVSRVVRHEKFNN---VTNDNDVMLVKLSANVALNANIQLVALQTSAL------PPGTLCNVSGWGTLQESSNKGSDVLRAVTVPIVSNALCNSTLYYRGLITVNMLCAGFDQGGKDACQGDSGGPLICDNKLK-----GLVSWG-LGCARPRYFGIYTDVSRLISWINN 248
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005493.1 (pep scaffold:Pmarinus_7.0:GL476632:243920:250733:-1 gene:ENSPMAG00000004970.1 transcript:ENSPMAT00000005493.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.383 bits (272), Expect = 9.556e-29
Identity = 83/258 (32.17%), Postives = 124/258 (48.06%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQ-GSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKF-------DGY----VSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVAS-NVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +I+NG  A+   +P  VS++ + G H CGG+L++   V+TAAHC                 ++ LGE+D        +   + K I HP + +       NDVALIK        DG     +S+T  N+             PG  C   GWG       DT   LQ+ A+ I++T  C ++  N+  +    +CAG G+ +TS C+ DSGGPL C      ++ VGIVS+G   C    +P V+TRV+ +  WI+Q
Sbjct:   26 RIVNGEEAMPGSWPWQVSLQSKTGFHFCGGSLIDPYWVVTAAHC----------GISPSEHRVILGEHDRSSSSEKVQTMTIAKAINHPQWDN---MSINNDVALIKLSQPAQMTDGVSAVCLSSTSDNF------------PPGLNCVTSGWGITNNFDSDTPPRLQQTALAIVATPTCQQLLANMNKITDVMICAG-GAGATS-CRRDSGGPLVCEKDGAWNL-VGIVSWGNSSC-STRIPAVYTRVTAIRSWIDQ 254
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002946.1 (pep scaffold:Pmarinus_7.0:GL477988:107792:112981:-1 gene:ENSPMAG00000002665.1 transcript:ENSPMAT00000002946.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.071 bits (266), Expect = 7.906e-28
Identity = 77/247 (31.17%), Postives = 121/247 (48.99%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQ-GSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +I+ G  A+   +P  VS++   G H CGG+L++   ++TAAHC            +    ++ LGE+D        +   + KVI HP +       + NDVALIK       T  + +    L   S   P G  C   GWG       DT   LQ+ A+ I++T  C ++F ++  + ++V   +G    S+C+ DSGGPL C      ++ VGIVS+G   C   ++P V+TRV+ +  WI+Q
Sbjct:   35 RIVKGEEAMPGSWPWQVSLQNNTGFHFCGGSLIDPYWIVTAAHC----------KIRPSEHRVILGEHDRSSSSEKVQTMTIAKVINHPQWDD---VSFNNDVALIKLPQPAQMT--DGVSAVCLSSTSDNVPAGLNCVTSGWGITNNFDSDTPPRLQQTALAIVATPTCQQLFASMNKI-TDVMICAGGAGASSCRCDSGGPLVCKKNGAWNL-VGIVSWGSSVC-STSMPVVYTRVTAIRSWIDQ 263
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009421.1 (pep scaffold:Pmarinus_7.0:GL476822:99973:112424:1 gene:ENSPMAG00000008474.1 transcript:ENSPMAT00000009421.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.531 bits (262), Expect = 3.510e-27
Identity = 82/254 (32.28%), Postives = 118/254 (46.46%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQG--------SHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDL-NSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRI-FTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYG-RVPCGQANVPTVFTRVSEVARWI 795
            +I+NG  A+ + +P  +S+             H+CGG LLN + VLTAAHC+            +YS  + LG+ +L+     +   Q+  + +HP + + F   YG D+A I+ +     T  N I+   L     I      C   GWGS+   G   S  LQ+A +  +S ++CS   +       S +CAG    ST  C GDSGGPL C   R   +  GI S+G    C     P VFTRVS  + WI
Sbjct:   31 RIVNGEDAVPNSWPWQISLATAWFPESPNDIYHTCGGVLLNSDWVLTAAHCI----------VTNYSQSVLLGKQNLHLFEEGQLHVQIKNIHVHPKWNALFPE-YGFDLAFIELNESAPIT--NKIQPATLPYPGHILSNNPECYATGWGSLSTDGPSPST-LQQAKLPFVSYAKCSSSEYWGTTVKPSMICAGDSLHST--CYGDSGGPLNCKTDRGWEVH-GITSFGFPTSCNFDTKPNVFTRVSGYSAWI 267
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009363.1 (pep scaffold:Pmarinus_7.0:GL476822:37454:60557:-1 gene:ENSPMAG00000008427.1 transcript:ENSPMAT00000009363.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.064 bits (253), Expect = 8.041e-26
Identity = 85/254 (33.46%), Postives = 123/254 (48.43%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQG--------SHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDL-NSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSEC-SRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSY-GRVPCGQANVPTVFTRVSEVARWI 795
            +I+NG  A  + +P  +S+            +H+CGG LLN + VLTAAHC+        NT  S+S  + LG+++L  +   +   Q+  + +HP++ + F    G D+ALI+ +  V  T  N I+   L     I      C   GWG +   G   S  LQ+  +  +S +EC S  +       S +CAG  SL  SAC GDSGGPL C   R   +  GI S+     C     P+VFTRVS  + WI
Sbjct:   28 RIVNGEDAAPNSWPWQISLATAWDPESPDVINHTCGGVLLNTDWVLTAAHCI--------NT--SFSQSVCLGKHNLITLEEGQLHVQIKNIHVHPNWNATFVE-RGFDLALIELNESVPIT--NKIQPATLPYPGHILSNNPECYATGWGILSTDGPSPST-LQQVKLPFVSYAECNSSEYWGTIVKPSMICAGD-SLH-SACNGDSGGPLNCKTDRGWEVH-GITSFVSNFGCNYYTKPSVFTRVSGYSAWI 264
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO34771 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNF5])

HSP 1 Score: 127.102 bits (318), Expect = 3.677e-35
Identity = 88/256 (34.38%), Postives = 131/256 (51.17%), Query Frame = 1 
Query:   40 SCSTITSGWKIINGTRAIMHEYPQMVSIKVQGS-HSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSG-SLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +C     G ++ING  A  H +P  +S++  G  HSCGGTL++   V+TA+HCV      + N   SY+  + +G ++      V++   V+ VI HP Y         ND+AL++    V   +   +    L  N    PG RC + GWGS +  G ++ R LQ+A + I S ++C   +  V   A ++CAG   S ++  C GDSGGPL C D  R ++  G VSYG++ C      TVF RV+    WI Q
Sbjct:    7 ACGRKPPGARVINGQNAQPHSWPWQISLRPYGRYHSCGGTLISDRWVVTASHCV------HKNPRPSYT--VVVGAHERNGKTAVQESIPVSHVIEHPEYDDR---KIKNDIALLELSRPVKFDREGKVGTACL-TNQQPTPGKRCYITGWGSTIGTG-NSPRILQQAMLPIASHNDCKNKYYGVSSTA-HLCAGEARSGASGGCNGDSGGPLVCEDNGRWYLH-GAVSYGKLHC-PTTYYTVFARVASYTDWIKQ 246
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO30908 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZF8])

HSP 1 Score: 122.479 bits (306), Expect = 1.345e-33
Identity = 83/247 (33.60%), Postives = 129/247 (52.23%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYS-MKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVY-GNDVALIKFDGYVS-NTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            +++NG  A  H +P  +S++V G H CGG+L+    VLTAAHCV          F   S   + +G + + +   +++ F++TK+  H     DF+  +  NDVAL+K D  +  + + N +   E   NS  + G +C + GWG ++  GQ  S  LQ+A + + S S C R  + +  V       +G +    C+GDSGGP  C +G R  ++ G VS+G+  CG  +  TVF RVS    WIN
Sbjct:   10 RVVNGDNAAQHSWPWQISLRVNGRHICGGSLITPEWVLTAAHCV--------EDFPHPSGYTVVVGAHRIKERSAIQQEFRLTKLFKH----KDFSMSHLKNDVALLKLDNPIQPSDKVNTVCLPE--RNSRAQVGAQCFITGWGRLVGGGQ-PSEILQQAMLPVASHSACDRKNSYLVPVEEKSMICAGGMGMGGCQGDSGGPFVCNEGGRWVLR-GAVSWGQPMCGTDHY-TVFARVSSFIDWIN 239
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO33459 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS64])

HSP 1 Score: 118.242 bits (295), Expect = 7.355e-32
Identity = 88/252 (34.92%), Postives = 131/252 (51.98%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYP-----QMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYV--ASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            ++ING  A  H +P     +M+S K    H CGG+L++   VLTAAHCV  +RN      + YS  +Y+G ++L     VE+   ++K+  H  Y+S       +DVALIK    VS +++         L+S   P G +C + GWG M+  G   +  LQ+A + + S S+C      +  V  A+ +CA  GS     C+GDSGGP  C +G +  ++ G VS+G V C   +  TVF RV+    WIN
Sbjct:    2 RVINGVDATAHAWPWQISLRMMSKKGDDYHFCGGSLIDSEWVLTAAHCVAGIRN-----PRRYS--VYVGAHELDGTTQVEEKISISKIYSHEKYSSSL---LTSDVALIKLSKAVSLSKHVNTVCLPSGLSSDEAPAGSKCFITGWGRMVAGGSGANT-LQQADLLVASHSDCQARMGYMLSVDKATMICA--GSQGKGGCQGDSGGPFVCEEGGKWVLR-GAVSWGHVNC-LTDHYTVFARVNSFISWIN 238
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO39625 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9K6])

HSP 1 Score: 117.087 bits (292), Expect = 2.634e-31
Identity = 88/267 (32.96%), Postives = 127/267 (47.57%), Query Frame = 1 
Query:   10 NILLFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKV-QGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQ-YNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQN 804
             +L+F   L SC  I    +I+ GT A   ++P    ++   G   CGG+L+    +LTA HCV           ++ S+ I LG        G EK + VTKVI HPSY       Y +D+AL+K D  V  T+  + +   ELD   +   G  C V GWG  L  G  T  +LQ+ ++ I S + C   + N +   S +CAG       AC+GDSGGP+ C +G R +I  G  S+G   C    +  V+ +V  +  WI   
Sbjct:    8 KVLIFAQRLGSCG-IRPNTRIVGGTAAKHGDWPWQAQLRTTSGFPYCGGSLIAPQWILTATHCV--------ERKQASSIVIRLGARRRVATVGTEKDYIVTKVITHPSYHK--PKTYSHDIALLKLDKPVLYTKNIHPVCLPELDPEPVD--GKHCWVTGWGR-LSSGGSTPDYLQQVSVPIRSRARCDSSYPN-KIHDSMICAGIDKGGIDACQGDSGGPMVCENGGRFYIH-GATSWG-YGCAAPGLYGVYAKVKYLLPWIKDE 257
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO44208 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW61])

HSP 1 Score: 115.546 bits (288), Expect = 4.287e-31
Identity = 84/249 (33.73%), Postives = 130/249 (52.21%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQ-GSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYI-KYGELDL-NSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSG-SLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQ 801
            +IING  A  H +P  +S++ + G H+CGG+L++   V+TAAHC+   RN N   +      + +G +       V++  +++++I HP Y +D   V  ND+ALI+     +  Q++   K G + L +    PG RC + GWG++    Q +   LQ+A + I S   C R + +V   A ++CAG   S +   C GDSGGPL C D     +  G VSYG   C   +  TVF RV+    WI +
Sbjct:    2 RIINGQNAQPHSWPWQISLRGRSGFHTCGGSLISDRWVVTAAHCI--HRNKNPGGYT-----VVVGAHKKRGSTSVQQSLRLSQIIEHPKY-NDRRIV--NDIALIEL---ATPVQFDSAGKVGTVCLTDQRPAPGKRCYITGWGAINGDTQQSPDILQQAMLPIASHENCRRKYGDVSSTA-HLCAGEARSDAAGGCNGDSGGPLVCEDNGSWFLH-GAVSYGLRNCPTTHY-TVFARVASYTDWIKR 234
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: tryp (trypsinogen [Source:NCBI gene;Acc:100125451])

HSP 1 Score: 118.627 bits (296), Expect = 9.023e-32
Identity = 89/261 (34.10%), Postives = 124/261 (47.51%), Query Frame = 1 
Query:   19 LFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            L  VLLI  +      KI+ G     H  P  VS+   G H CGG+L+N N V++AAHC  S             +++ LGE+ +    G E+    ++VI HPSY S   Y   ND+ LIK     +  QY       + L S   P G  C V GWG+ + P  D  + LQ   I ILS S+CS  +  +    S  CAG       +C+GDSGGP+ C    +     GIVS+G   C + N P V+ +V   + W++
Sbjct:    4 LVFVLLIGAAFALDDDKIVGGYECTPHSQPHQVSLNA-GYHFCGGSLVNQNWVVSAAHCYQS------------RVEVRLGEHHIRNNDGTEQFITSSRVIRHPSYNS---YTIDNDIMLIKLSTPATLNQY----VQPVSLPSGCAPAGTMCLVSGWGNTMSPADDGDK-LQCLNIPILSDSDCSNSYPGM-ITNSMFCAGYLEGGKDSCQGDSGGPVVCNGQLQ-----GIVSWG-YGCAERNHPGVYAKVCIFSDWLD 236
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000027744.1 (trypsin-2 [Source:NCBI gene;Acc:101161921])

HSP 1 Score: 118.627 bits (296), Expect = 9.023e-32
Identity = 89/261 (34.10%), Postives = 124/261 (47.51%), Query Frame = 1 
Query:   19 LFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKP-GDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            L  VLLI  +      KI+ G     H  P  VS+   G H CGG+L+N N V++AAHC  S             +++ LGE+ +    G E+    ++VI HPSY S   Y   ND+ LIK     +  QY       + L S   P G  C V GWG+ + P  D  + LQ   I ILS S+CS  +  +    S  CAG       +C+GDSGGP+ C    +     GIVS+G   C + N P V+ +V   + W++
Sbjct:    4 LVFVLLIGAAFALDDDKIVGGYECTPHSQPHQVSLNA-GYHFCGGSLVNQNWVVSAAHCYQS------------RVEVRLGEHHIRNNDGTEQFITSSRVIRHPSYNS---YTIDNDIMLIKLSTPATLNQY----VQPVSLPSGCAPAGTMCLVSGWGNTMSPADDGDK-LQCLNIPILSDSDCSNSYPGM-ITNSMFCAGYLEGGKDSCQGDSGGPVVCNGQLQ-----GIVSWG-YGCAERNHPGVYAKVCIFSDWLD 236
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: zgc:112285 (elastase-1 [Source:NCBI gene;Acc:101161025])

HSP 1 Score: 120.168 bits (300), Expect = 2.282e-31
Identity = 86/257 (33.46%), Postives = 126/257 (49.03%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQ--GS----HSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSI-TKPGDRCEVVGWGSMLPPGQDT---SRFLQKAAINILSTSEC-SRIFTNVRYVASNVCAG--SGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWIN 798
            +I++G  A  H +P  VS++V+  GS    H CGGTL++ N VLTAAHC    +  +       S +I LG++ L +    E+IF V ++  H S+          D+AL+K    +  +  N+I+Y  L       +PG  C V GWG     G+D    +  L +A + I+    C  + F   R   S +CAG        +AC+GDSGGPL C   R      G+VS+G + C   N P+VFTR +    WI 
Sbjct:   77 RIVSGNEARPHSWPWQVSLQVRPRGSKHYVHVCGGTLIHKNWVLTAAHCFQKGKAEDAG-----SWRIVLGKHQLKRSETAERIFPVKRIYRHESFRYPTHSELDYDIALVKAGTDIPPS--NFIRYACLPRKQTGLRPGHYCWVTGWGDTRG-GKDNVSLAEALNQARLPIIDFKTCRQKKFWGDRVRDSMICAGFRDTEDPPAACQGDSGGPLLCQLDRDRWEVHGVVSFGPIGCTVENKPSVFTRTATYIPWIE 325
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: CELA1 (elastase-1 [Source:NCBI gene;Acc:101156080])

HSP 1 Score: 117.857 bits (294), Expect = 3.399e-31
Identity = 83/251 (33.07%), Postives = 128/251 (51.00%), Query Frame = 1 
Query:   67 KIINGTRAIMHEYPQMVSIKVQGS----HSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDR-CEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRI-FTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRV-PCGQANVPTVFTRVSEVARWIN 798
            +++ G  A  + +P  +S++        H+CGGTL+    V+TAAHCV S R W          ++ LGE+D+Y   G E+   V++V +HP + S+     G D+AL++    V  T  +Y++   L  +    P +  C + GWG +   G   S  L++A + ++  S CSR  +       + VCAG G  + S C GDSGGPL C    ++++  GI S+G    C     PTVFTRVS    W+N
Sbjct:   31 RVVGGEVASPNSWPWQISLQYLSGGSYYHTCGGTLIQRGWVMTAAHCVDSSRTW----------RVVLGEHDIYSSGGTEQYIGVSQVYVHPQWDSNRV-SNGYDIALLRLASDV--TLNSYVQLASLPPSGQILPHNNLCYITGWG-LTSTGGSLSSQLKEAYLPVVDHSTCSRSDWWGSTVKTTMVCAGGG--AESGCNGDSGGPLNCQVSGKYYVH-GITSFGSAYGCNYPQKPTVFTRVSAYIDWMN 264
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: GZMM (duodenase-1 [Source:NCBI gene;Acc:101164468])

HSP 1 Score: 117.472 bits (293), Expect = 3.653e-31
Identity = 80/250 (32.00%), Postives = 113/250 (45.20%), Query Frame = 1 
Query:   55 TSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNT---QYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWI 795
             +G  I+ G  A  H  P M S++V+G H CGG L+  + VLTAAHC   +              + LG   L +     + F+V + I HP+Y         ND+ L+K DG    T   Q   +K G +       P  +C   GWG  +   +  +  LQ+  + IL+   C + + NVR + S VC          C GDSGGP+ C DG       GIVS+    CG  + P V+TR+S    WI
Sbjct:   17 AAGSHIVGGRDAAPHSRPYMASLQVRGQHICGGALVREDFVLTAAHCDLPI-----------PFTVVLGADLLQENEPSRQTFRVLRSIPHPNYNE-----LSNDIMLLKLDGRARLTPEVQVIPLKSGTV------GPASQCITAGWGD-IGDNRTIANRLQEVDVTILAQRTCRQRWGNVRVLRSMVCGVGARSFQGFCSGDSGGPMIC-DGE----AAGIVSFSGRRCGDPSTPDVYTRISSFRSWI 238
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000042349.1 (SMESG000042349.1)

HSP 1 Score: 494.967 bits (1273), Expect = 1.114e-179
Identity = 236/239 (98.74%), Postives = 238/239 (99.58%), Query Frame = 1 
Query:   94 MHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN 810
            MHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNV YVASNVCAGSGSLSTSAC+GDSGGPLFCTDGRRHHIQVGIVSYG+VPCGQANVPTVFTRVSEVARWINQNAN
Sbjct:    1 MHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVWYVASNVCAGSGSLSTSACRGDSGGPLFCTDGRRHHIQVGIVSYGQVPCGQANVPTVFTRVSEVARWINQNAN 239
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000042388.1 (SMESG000042388.1)

HSP 1 Score: 494.967 bits (1273), Expect = 1.181e-179
Identity = 236/239 (98.74%), Postives = 236/239 (98.74%), Query Frame = 1 
Query:   94 MHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN 810
            MHEYPQMVSIKVQGSH CGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQK AINILS SECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN
Sbjct:    1 MHEYPQMVSIKVQGSHFCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKTAINILSNSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN 239
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000042386.1 (SMESG000042386.1)

HSP 1 Score: 379.407 bits (973), Expect = 1.845e-133
Identity = 164/265 (61.89%), Postives = 215/265 (81.13%), Query Frame = 1 
Query:    1 MIQNILLFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWI 795
            M Q ++  L +++S   I++  K ING++ IMH++PQMVSIK+  +H CGGTLLNGNTVLT AHC+W +R WN + FK Y  +I+LGEYDL+ MYG+EK FQVTK+I+HPSYTS+ ++ YGNDVAL+KFDGY+ NT Y+YIKY  LD+N I+KPGDRCEVVGWGS+LPPG++T+R LQ+A++ ++S  +CS+ F NV+Y+ SN+CAG+G+   SACKGD GGPLFCTDG+  H+QVGIVSYG VPCGQ  +P VFTR+S VA+WI
Sbjct:    1 MSQKVVFHLFVVLSFCAISTALKTINGSQEIMHQFPQMVSIKLMDNHICGGTLLNGNTVLTTAHCIWDLRYWNNDYFKYYKFRIFLGEYDLHYMYGIEKDFQVTKIIMHPSYTSEMSFYYGNDVALVKFDGYIENTDYDYIKYNVLDINGISKPGDRCEVVGWGSLLPPGENTARLLQEASLIVMSNEDCSKTFYNVKYIDSNICAGTGNSDASACKGDLGGPLFCTDGKNQHVQVGIVSYGHVPCGQPYIPIVFTRISTVAKWI 265
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000042389.1 (SMESG000042389.1)

HSP 1 Score: 328.946 bits (842), Expect = 4.946e-114
Identity = 148/239 (61.92%), Postives = 189/239 (79.08%), Query Frame = 1 
Query:   94 MHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYVASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQANVPTVFTRVSEVARWINQNAN 810
            MH+YPQ+VSI++ G H CGGTLLNGNTVLTAAHCVW MR + ++ F+ + +K+ LGEYDL+ + G EK+ QV K+++HP+Y    AY+ GNDVAL+KFDG++SN +  Y+KY +LD +    PG RCEVVGWGSM P G+DTS+FLQKA ++I+ST ECS+ + NV+ V SN+CAGSGSLS SACKGDSGGPLFC D     IQVGIVSY ++PCGQAN PTV+TR+SEVA+WI  N+ 
Sbjct:    1 MHQYPQIVSIQLDGDHICGGTLLNGNTVLTAAHCVWDMRYYTMDWFEYHKVKVVLGEYDLHHISGKEKVLQVNKIMMHPTYKRAKAYIDGNDVALMKFDGFISNDETEYVKYIKLDTDLKVSPGKRCEVVGWGSMQPDGEDTSQFLQKAFLDIVSTEECSKTYPNVQNVPSNICAGSGSLSISACKGDSGGPLFCRDPANRLIQVGIVSYSKMPCGQANKPTVYTRISEVAKWITLNSK 239
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000042396.1 (SMESG000042396.1)

HSP 1 Score: 232.261 bits (591), Expect = 1.008e-76
Identity = 108/182 (59.34%), Postives = 140/182 (76.92%), Query Frame = 1 
Query:    7 QNILLFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCGGTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKIFQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNSITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINI 552
            +NIL+  V LI  ST+++ WK+INGT++I+HEYPQMVSI++ G H CGGTLLN NTVLTAAHC+W M +W L T K Y ++I LGEYDL ++ G EKIFQVTK ++HP YT + +Y+ GNDV LIKFDG V N ++ YIKY E    S  + G+RCEVVGWGS+ P G+ +SRFLQKA++N+
Sbjct:    4 KNILI--VFLIFISTVSAEWKVINGTQSILHEYPQMVSIRLLGEHICGGTLLNENTVLTAAHCIWPMTDWKLETLKEYKVEIVLGEYDLERVSGEEKIFQVTKNLVHPDYTYEMSYLNGNDVGLIKFDGKVQNNEFQYIKYTEYQNISTYEIGERCEVVGWGSIDPSGRGSSRFLQKASLNV 183
The following BLAST results are available for this feature:
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KLK139.472e-3733.20kallikrein related peptidase 13 [Source:HGNC Symbo... [more]
KLK152.731e-3231.68kallikrein related peptidase 15 [Source:HGNC Symbo... [more]
CTRL7.183e-3233.73chymotrypsin like [Source:HGNC Symbol;Acc:HGNC:252... [more]
KLK152.744e-3131.52kallikrein related peptidase 15 [Source:HGNC Symbo... [more]
KLK84.325e-2930.49kallikrein related peptidase 8 [Source:HGNC Symbol... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
try-17.371e-2431.23TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
svh-11.895e-2127.49HGF/MSP/plasminogen-like protein [Source:UniProtK... [more]
try-33.629e-1326.38TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
try-35.312e-1326.38TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG118361.404e-3032.68gene:FBgn0039272 transcript:FBtr0309271[more]
CG118362.645e-3032.68gene:FBgn0039272 transcript:FBtr0473579[more]
CG328081.167e-2933.86gene:FBgn0052808 transcript:FBtr0070295[more]
l(2)k059114.498e-2931.03gene:FBgn0284244 transcript:FBtr0305556[more]
tpr6.332e-2932.41gene:FBgn0034661 transcript:FBtr0071743[more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:1122853.387e-3233.59zgc:112285 [Source:ZFIN;Acc:ZDB-GENE-050913-132][more]
cela1.69.980e-3234.13chymotrypsin like elastase family member 1, tandem... [more]
cela1.61.094e-3134.13chymotrypsin like elastase family member 1, tandem... [more]
si:ch73-182e20.41.977e-3134.35si:ch73-182e20.4 [Source:ZFIN;Acc:ZDB-GENE-131127-... [more]
ctrl2.888e-3133.20chymotrypsin-like [Source:ZFIN;Acc:ZDB-GENE-040912... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000015569.13.231e-3131.15pep primary_assembly:Xenopus_tropicalis_v9.1:9:281... [more]
ENSXETT00000030871.14.534e-3132.61pep primary_assembly:Xenopus_tropicalis_v9.1:9:282... [more]
ENSXETT00000015681.11.196e-3033.46pep primary_assembly:Xenopus_tropicalis_v9.1:9:272... [more]
trim361.829e-3033.33tripartite motif containing 36 [Source:Xenbase;Acc... [more]
trim363.338e-3033.33tripartite motif containing 36 [Source:Xenbase;Acc... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Klk132.232e-3430.35kallikrein related-peptidase 13 [Source:MGI Symbol... [more]
Gzmm8.246e-3333.73granzyme M (lymphocyte met-ase 1) [Source:MGI Symb... [more]
Klk156.976e-3230.71kallikrein related-peptidase 15 [Source:MGI Symbol... [more]
Klk61.649e-3127.94kallikrein related-peptidase 6 [Source:MGI Symbol;... [more]
Klk61.649e-3127.94kallikrein related-peptidase 6 [Source:MGI Symbol;... [more]
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BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9UKR3|KLK13_HUMAN4.549e-3633.20Kallikrein-13 OS=Homo sapiens OX=9606 GN=KLK13 PE=... [more]
sp|Q06605|GRZ1_RAT7.363e-3331.54Granzyme-like protein 1 OS=Rattus norvegicus OX=10... [more]
sp|P80646|CTRB_GADMO2.120e-3233.60Chymotrypsin B OS=Gadus morhua OX=8049 PE=1 SV=1[more]
sp|P18291|GRAB_RAT6.835e-3231.50Granzyme B OS=Rattus norvegicus OX=10116 GN=Gzmb P... [more]
sp|Q03238|GRAM_RAT3.100e-3133.73Granzyme M (Fragment) OS=Rattus norvegicus OX=1011... [more]
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BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
H2DRI75.358e-11777.72Trypsin-like serine protease OS=Dugesia japonica O... [more]
A0A1I8GT163.280e-5238.81Peptidase S1 domain-containing protein OS=Macrosto... [more]
A0A1I8JAW54.682e-5238.81Peptidase S1 domain-containing protein OS=Macrosto... [more]
A0A1I8JHD83.302e-4036.57Peptidase S1 domain-containing protein OS=Macrosto... [more]
U5EP401.192e-3835.61Putative trypsin-like serine protease OS=Corethrel... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000043830.12.840e-3340.09elastase-1-like [Source:NCBI gene;Acc:103036513][more]
ENSAMXT00000048530.11.103e-3230.60pep primary_assembly:Astyanax_mexicanus-2.0:13:202... [more]
ENSAMXT00000014374.22.078e-3235.74chymotrypsinogen A-like [Source:NCBI gene;Acc:1030... [more]
ENSAMXT00000014359.29.678e-3134.40pep primary_assembly:Astyanax_mexicanus-2.0:8:2090... [more]
si:dkey-32n7.91.071e-3034.13chymotrypsin-like protease CTRL-1 [Source:NCBI gen... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008289.11.466e-2929.44pep scaffold:Pmarinus_7.0:GL480450:20964:30734:1 g... [more]
ENSPMAT00000005493.19.556e-2932.17pep scaffold:Pmarinus_7.0:GL476632:243920:250733:-... [more]
ENSPMAT00000002946.17.906e-2831.17pep scaffold:Pmarinus_7.0:GL477988:107792:112981:-... [more]
ENSPMAT00000009421.13.510e-2732.28pep scaffold:Pmarinus_7.0:GL476822:99973:112424:1 ... [more]
ENSPMAT00000009363.18.041e-2633.46pep scaffold:Pmarinus_7.0:GL476822:37454:60557:-1 ... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO347713.677e-3534.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO309081.345e-3333.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO334597.355e-3234.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO396252.634e-3132.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO442084.287e-3133.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tryp9.023e-3234.10trypsinogen [Source:NCBI gene;Acc:100125451][more]
ENSORLT00000027744.19.023e-3234.10trypsin-2 [Source:NCBI gene;Acc:101161921][more]
zgc:1122852.282e-3133.46elastase-1 [Source:NCBI gene;Acc:101161025][more]
CELA13.399e-3133.07elastase-1 [Source:NCBI gene;Acc:101156080][more]
GZMM3.653e-3132.00duodenase-1 [Source:NCBI gene;Acc:101164468][more]
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BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000042349.11.114e-17998.74SMESG000042349.1[more]
SMESG000042388.11.181e-17998.74SMESG000042388.1[more]
SMESG000042386.11.845e-13361.89SMESG000042386.1[more]
SMESG000042389.14.946e-11461.92SMESG000042389.1[more]
SMESG000042396.11.008e-7659.34SMESG000042396.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031804 ID=SMED30031804|Name=Peptidase S1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=875bp
ATGATTCAAAATATTTTATTATTTCTGGTGCTATTGATCTCCTGCAGCAC
AATCACTTCAGGGTGGAAAATAATCAACGGGACTAGAGCGATAATGCACG
AATATCCACAAATGGTGTCCATAAAAGTCCAGGGTAGCCATTCCTGTGGA
GGAACATTGTTGAATGGAAACACAGTACTGACCGCAGCGCATTGTGTTTG
GTCAATGAGGAATTGGAATTTAAATACATTCAAAAGTTATAGCATGAAGA
TATATCTGGGCGAATATGATTTATATCAAATGTATGGAGTTGAAAAGATC
TTTCAAGTAACAAAAGTAATCATTCACCCATCGTATACAAGCGATTTCGC
CTATGTATACGGAAATGATGTGGCCCTGATCAAATTCGATGGCTACGTAT
CGAATACTCAATATAACTACATAAAGTACGGTGAATTAGACCTCAATTCA
ATTACTAAGCCAGGGGATCGGTGTGAAGTTGTAGGGTGGGGAAGTATGCT
ACCTCCAGGACAAGATACTTCGAGATTCTTACAAAAGGCGGCAATCAATA
TTTTATCGACTTCTGAATGTAGTAGAATATTCACGAATGTTCGATACGTT
GCCAGCAACGTTTGCGCTGGTAGTGGCAGTCTGTCAACTTCAGCTTGTAA
AGGAGATTCGGGAGGACCATTGTTTTGCACTGATGGACGAAGACATCATA
TTCAAGTAGGAATTGTCAGTTACGGACGAGTACCATGTGGTCAAGCAAAT
GTACCAACCGTTTTCACTCGAGTATCTGAAGTAGCAAGATGGATAAATCA
GAATGCAAACTAAATTTCTTTTCAGTGATTTTATTTGTGTCTAAATATAA
TGAGATATGAATATTCAAAAAAAAA
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protein sequence of SMED30031804-orf-1

>SMED30031804-orf-1 ID=SMED30031804-orf-1|Name=SMED30031804-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=271bp
MIQNILLFLVLLISCSTITSGWKIINGTRAIMHEYPQMVSIKVQGSHSCG
GTLLNGNTVLTAAHCVWSMRNWNLNTFKSYSMKIYLGEYDLYQMYGVEKI
FQVTKVIIHPSYTSDFAYVYGNDVALIKFDGYVSNTQYNYIKYGELDLNS
ITKPGDRCEVVGWGSMLPPGQDTSRFLQKAAINILSTSECSRIFTNVRYV
ASNVCAGSGSLSTSACKGDSGGPLFCTDGRRHHIQVGIVSYGRVPCGQAN
VPTVFTRVSEVARWINQNAN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0008236serine-type peptidase activity
GO:0016787hydrolase activity
GO:0004252serine-type endopeptidase activity
GO:0008233peptidase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR001314Peptidase_S1A
IPR001254Trypsin_dom
IPR033116TRYPSIN_SER
IPR018114TRYPSIN_HIS
IPR009003Peptidase_S1_PA
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001314Peptidase S1A, chymotrypsin familyPRINTSPR00722CHYMOTRYPSINcoord: 213..225
score: 61.69
coord: 50..65
score: 58.94
coord: 119..133
score: 29.23
IPR001254Serine proteases, trypsin domainSMARTSM00020trypsin_2coord: 23..265
e-value: 1.4E-68
score: 243.8
IPR001254Serine proteases, trypsin domainPFAMPF00089Trypsincoord: 24..265
e-value: 7.2E-51
score: 173.1
IPR001254Serine proteases, trypsin domainPROSITEPS50240TRYPSIN_DOMcoord: 24..270
score: 29.888
IPR001254Serine proteases, trypsin domainCDDcd00190Tryp_SPccoord: 24..268
e-value: 2.61848E-71
score: 217.144
NoneNo IPR availableGENE3DG3DSA:2.40.10.10coord: 17..270
e-value: 3.2E-60
score: 205.5
NoneNo IPR availablePANTHERPTHR24276FAMILY NOT NAMEDcoord: 14..269
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.899
NoneNo IPR availableTMHMMTMhelixcoord: 5..22
IPR018114Serine proteases, trypsin family, histidine active sitePROSITEPS00134TRYPSIN_HIScoord: 60..65
IPR033116Serine proteases, trypsin family, serine active sitePROSITEPS00135TRYPSIN_SERcoord: 214..225
IPR009003Peptidase S1, PA clanSUPERFAMILYSSF50494Trypsin-like serine proteasescoord: 6..269