Myocyte-specific enhancer factor 2A homolog

Overview
NameMyocyte-specific enhancer factor 2A homolog
Smed IDSMED30031794
Length (bp)1866
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Myocyte-specific enhancer factor 2A homolog (SMED30031794) t-SNE clustered cells

Violin plots show distribution of expression levels for Myocyte-specific enhancer factor 2A homolog (SMED30031794) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Myocyte-specific enhancer factor 2A homolog (SMED30031794) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Myocyte-specific enhancer factor 2A homolog (SMED30031794) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30031794

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30031794SMESG000040479.1 SMESG000040478.1 SMESG000038141.1 dd_Smed_v4_6889_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30031794SMESG000040479.1 SMESG000040478.1 SMESG000038141.1 dd_Smed_v4_6889_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30031794SMESG000040479.1 SMESG000040478.1 SMESG000038141.1 dd_Smed_v4_6889_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Human
Match: MEF2D (myocyte enhancer factor 2D [Source:HGNC Symbol;Acc:HGNC:6997])

HSP 1 Score: 147.132 bits (370), Expect = 5.226e-41
Identity = 67/91 (73.63%), Postives = 80/91 (87.91%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Human
Match: MEF2D (myocyte enhancer factor 2D [Source:HGNC Symbol;Acc:HGNC:6997])

HSP 1 Score: 147.132 bits (370), Expect = 5.226e-41
Identity = 67/91 (73.63%), Postives = 80/91 (87.91%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Human
Match: MEF2C (myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996])

HSP 1 Score: 149.443 bits (376), Expect = 1.355e-40
Identity = 71/105 (67.62%), Postives = 85/105 (80.95%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDD 344
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  +KK E+  C   S D D
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK-ENKGC--ESPDPD 102
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Human
Match: MEF2C (myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996])

HSP 1 Score: 149.058 bits (375), Expect = 1.376e-40
Identity = 71/105 (67.62%), Postives = 85/105 (80.95%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDD 344
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  +KK E+  C   S D D
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK-ENKGC--ESPDPD 102
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Human
Match: MEF2C (myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996])

HSP 1 Score: 148.288 bits (373), Expect = 1.486e-40
Identity = 71/105 (67.62%), Postives = 85/105 (80.95%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDD 344
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  +KK E+  C   S D D
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK-ENKGC--ESPDPD 102
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Celegans
Match: mef-2 (Related to vertebrate MEF2 transcription factor [Source:UniProtKB/TrEMBL;Acc:Q9U325])

HSP 1 Score: 151.369 bits (381), Expect = 1.506e-40
Identity = 69/104 (66.35%), Postives = 86/104 (82.69%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDD 341
            MGRKKI+I +I+DER RQVTF KRK GLMKKAYELSVLCDCEIALI+FN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  ++K E      NSDD+
Sbjct:    1 MGRKKIQITRIQDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIVFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNNDIMEALNRK-EGNQGGGNSDDE 103
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Celegans
Match: unc-120 (pep chromosome:WBcel235:I:8460225:8463015:1 gene:WBGene00006844.1 transcript:D1081.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-120)

HSP 1 Score: 59.6918 bits (143), Expect = 1.901e-9
Identity = 24/65 (36.92%), Postives = 43/65 (66.15%), Query Frame = 3 
Query:   33 GRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTIL 227
            GR KI+++ I ++  R  TF+KRK+G+MKKA+ELS L   ++ L++ +    +Y YA+  +  ++
Sbjct:   46 GRVKIKMEYINNKLRRYTTFSKRKTGIMKKAFELSTLTGTQVMLLVASETGHVYTYATPKLQPMI 110
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Fly
Match: Mef2 (gene:FBgn0011656 transcript:FBtr0088446)

HSP 1 Score: 145.591 bits (366), Expect = 4.143e-37
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK G+MKKAYELSVLCDCEIALIIF+++NKLYQYAS+DMD +LL+YT+Y EPHES TNK +
Sbjct:    1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVLLKYTEYNEPHESLTNKNI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Fly
Match: Mef2 (gene:FBgn0011656 transcript:FBtr0088445)

HSP 1 Score: 145.591 bits (366), Expect = 4.531e-37
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK G+MKKAYELSVLCDCEIALIIF+++NKLYQYAS+DMD +LL+YT+Y EPHES TNK +
Sbjct:    1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVLLKYTEYNEPHESLTNKNI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Fly
Match: Mef2 (gene:FBgn0011656 transcript:FBtr0088444)

HSP 1 Score: 145.591 bits (366), Expect = 4.862e-37
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK G+MKKAYELSVLCDCEIALIIF+++NKLYQYAS+DMD +LL+YT+Y EPHES TNK +
Sbjct:    1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVLLKYTEYNEPHESLTNKNI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Fly
Match: Mef2 (gene:FBgn0011656 transcript:FBtr0088447)

HSP 1 Score: 145.206 bits (365), Expect = 4.909e-37
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK G+MKKAYELSVLCDCEIALIIF+++NKLYQYAS+DMD +LL+YT+Y EPHES TNK +
Sbjct:    1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVLLKYTEYNEPHESLTNKNI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Fly
Match: Mef2 (gene:FBgn0011656 transcript:FBtr0330707)

HSP 1 Score: 145.206 bits (365), Expect = 6.430e-37
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK G+MKKAYELSVLCDCEIALIIF+++NKLYQYAS+DMD +LL+YT+Y EPHES TNK +
Sbjct:    1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVLLKYTEYNEPHESLTNKNI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Zebrafish
Match: mef2ab (myocyte enhancer factor 2ab [Source:ZFIN;Acc:ZDB-GENE-120614-2])

HSP 1 Score: 144.436 bits (363), Expect = 7.750e-41
Identity = 64/88 (72.73%), Postives = 79/88 (89.77%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVA 293
            MGRKKI+I +I +ER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +V+
Sbjct:    1 MGRKKIQITRIMEERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEVS 88
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Zebrafish
Match: mef2ab (myocyte enhancer factor 2ab [Source:ZFIN;Acc:ZDB-GENE-120614-2])

HSP 1 Score: 144.436 bits (363), Expect = 7.750e-41
Identity = 64/88 (72.73%), Postives = 79/88 (89.77%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVA 293
            MGRKKI+I +I +ER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +V+
Sbjct:    1 MGRKKIQITRIMEERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEVS 88
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Zebrafish
Match: mef2ca (myocyte enhancer factor 2ca [Source:ZFIN;Acc:ZDB-GENE-980526-253])

HSP 1 Score: 143.28 bits (360), Expect = 1.440e-40
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++
Sbjct:    1 MGRKKIQIARIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Zebrafish
Match: mef2ca (myocyte enhancer factor 2ca [Source:ZFIN;Acc:ZDB-GENE-980526-253])

HSP 1 Score: 143.28 bits (360), Expect = 1.440e-40
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++
Sbjct:    1 MGRKKIQIARIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Zebrafish
Match: mef2ca (myocyte enhancer factor 2ca [Source:ZFIN;Acc:ZDB-GENE-980526-253])

HSP 1 Score: 143.28 bits (360), Expect = 1.440e-40
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKEL 281
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++
Sbjct:    1 MGRKKIQIARIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDI 84
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Xenopus
Match: mef2a (myocyte enhancer factor 2A [Source:NCBI gene;Acc:100216045])

HSP 1 Score: 145.976 bits (367), Expect = 1.374e-40
Identity = 66/91 (72.53%), Postives = 78/91 (85.71%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN +NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNGSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLKKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:NCBI gene;Acc:780389])

HSP 1 Score: 155.606 bits (392), Expect = 1.590e-40
Identity = 72/115 (62.61%), Postives = 89/115 (77.39%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D DD  +    M+D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGDDSIDQSPLMED 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Xenopus
Match: mef2a (myocyte enhancer factor 2A [Source:NCBI gene;Acc:100216045])

HSP 1 Score: 148.288 bits (373), Expect = 1.822e-40
Identity = 66/91 (72.53%), Postives = 78/91 (85.71%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN +NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNGSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLKKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:NCBI gene;Acc:780389])

HSP 1 Score: 155.606 bits (392), Expect = 2.077e-40
Identity = 72/115 (62.61%), Postives = 89/115 (77.39%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D DD  +    M+D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGDDSIDQSPLMED 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:NCBI gene;Acc:780389])

HSP 1 Score: 155.221 bits (391), Expect = 3.111e-40
Identity = 72/115 (62.61%), Postives = 89/115 (77.39%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D DD  +    M+D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGDDSIDQSPLMED 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Mouse
Match: Mef2a (myocyte enhancer factor 2A [Source:MGI Symbol;Acc:MGI:99532])

HSP 1 Score: 150.599 bits (379), Expect = 3.090e-41
Identity = 71/115 (61.74%), Postives = 90/115 (78.26%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++  V + +++  N   + D DD  E+    +D
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDI--VETLRKKGLNGCESPDADDYFEHSPLSED 113
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Mouse
Match: Mef2c (myocyte enhancer factor 2C [Source:MGI Symbol;Acc:MGI:99458])

HSP 1 Score: 145.591 bits (366), Expect = 4.420e-41
Identity = 66/91 (72.53%), Postives = 79/91 (86.81%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  +KK
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Mouse
Match: Mef2c (myocyte enhancer factor 2C [Source:MGI Symbol;Acc:MGI:99458])

HSP 1 Score: 145.206 bits (365), Expect = 9.993e-41
Identity = 66/91 (72.53%), Postives = 79/91 (86.81%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  +KK
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Mouse
Match: Mef2c (myocyte enhancer factor 2C [Source:MGI Symbol;Acc:MGI:99458])

HSP 1 Score: 148.673 bits (374), Expect = 1.386e-40
Identity = 66/91 (72.53%), Postives = 79/91 (86.81%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  +KK
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Mouse
Match: Mef2c (myocyte enhancer factor 2C [Source:MGI Symbol;Acc:MGI:99458])

HSP 1 Score: 145.206 bits (365), Expect = 1.475e-40
Identity = 66/91 (72.53%), Postives = 78/91 (85.71%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. UniProt/SwissProt
Match: sp|Q03414|MEF2A_XENLA (Myocyte-specific enhancer factor 2A homolog OS=Xenopus laevis OX=8355 GN=mef2a PE=1 SV=2)

HSP 1 Score: 155.992 bits (393), Expect = 1.065e-39
Identity = 75/144 (52.08%), Postives = 101/144 (70.14%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDDIS-----NELYYSRDNNIKQNENQAVESA 446
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK       +N  +  +D+ + E +  S     ++  + RD  + + EN+  +S 
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKK------GLNGCESPDDQRYFEEETFSKLIEDSDFVFKRDPALNKKENRGCDSP 138
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. UniProt/SwissProt
Match: sp|Q03413|MEF2D_XENLA (Myocyte-specific enhancer factor 2D homolog OS=Xenopus laevis OX=8355 GN=mef2d PE=1 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 2.067e-39
Identity = 72/115 (62.61%), Postives = 89/115 (77.39%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D DD  +    M+D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGDDSIDQSPLMED 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. UniProt/SwissProt
Match: sp|O89038|MEF2D_RAT (Myocyte-specific enhancer factor 2D OS=Rattus norvegicus OX=10116 GN=Mef2d PE=1 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 2.825e-39
Identity = 71/115 (61.74%), Postives = 89/115 (77.39%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D +D  E    ++D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLED 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. UniProt/SwissProt
Match: sp|Q63943|MEF2D_MOUSE (Myocyte-specific enhancer factor 2D OS=Mus musculus OX=10090 GN=Mef2d PE=1 SV=2)

HSP 1 Score: 154.451 bits (389), Expect = 3.627e-39
Identity = 71/115 (61.74%), Postives = 89/115 (77.39%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D +D  E    ++D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLED 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. UniProt/SwissProt
Match: sp|Q14814|MEF2D_HUMAN (Myocyte-specific enhancer factor 2D OS=Homo sapiens OX=9606 GN=MEF2D PE=1 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 4.689e-39
Identity = 71/115 (61.74%), Postives = 89/115 (77.39%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D +D  E    ++D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLED 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. TrEMBL
Match: A0A0R3Q5I5 (MADS-box domain-containing protein OS=Brugia timori OX=42155 GN=BTMF_LOCUS919 PE=4 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 2.398e-40
Identity = 71/104 (68.27%), Postives = 89/104 (85.58%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDD 341
            MGRKKI+I +I+DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ + A +++ES +  V SD+D
Sbjct:    1 MGRKKIQITRIQDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIME-ALQRKESKSGGVESDED 103
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. TrEMBL
Match: A0A087UPT2 (Myocyte-specific enhancer factor 2A (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_16773 PE=4 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 2.923e-39
Identity = 72/110 (65.45%), Postives = 87/110 (79.09%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENH 359
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  SKK E  N T   D  + D+ +
Sbjct:    1 MGRKKIQISRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALSKK-EHKNSTNGCDSPEPDQEY 109
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. TrEMBL
Match: T1KCI5 (MADS-box domain-containing protein OS=Tetranychus urticae OX=32264 GN=107362383 PE=4 SV=1)

HSP 1 Score: 160.999 bits (406), Expect = 4.291e-39
Identity = 106/271 (39.11%), Postives = 141/271 (52.03%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDDISNELYYSRDNNIKQNENQAVE--SAHGLMNRNEESIIRISPGMFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLS---------------------SIVLQQGNMGKSDTPQAESFLIVSNANL 773
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +  +KK E  N     D  + DE    M+  S + Y    N I +     ++   AH   NR++ S  R+SP     + +      + S+ + P Q               L  Q  +    P  S  +LD  SG S                     SIV  +GN+  + TP   + +I +N  L
Sbjct:    1 MGRKKIQISRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLNKK-EHKNSANGCDSPEPDEASYTMNQRSEQNY----NKISEQYEMMLQRNPAHINGNRSQPSSSRLSPVPVTVALNSSPYPNQDSSLLQPAQ---------------LSPQPASISPRPSSSGAMLDMTSGSSNGFHHQPCSPSSLSGESSSPNSIVCIKGNVSPNLTPANSTSVIPTNVTL 251
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. TrEMBL
Match: A0A1I8CM09 (MADS-box domain-containing protein OS=Rhabditophanes sp. KR3021 OX=114890 PE=4 SV=1)

HSP 1 Score: 159.073 bits (401), Expect = 4.642e-39
Identity = 70/104 (67.31%), Postives = 84/104 (80.77%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDD 341
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ D   +K        +SDDD
Sbjct:    1 MGRKKIQITRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNNDIMDALQRKEVKGGIGCDSDDD 104
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. TrEMBL
Match: J9F2L7 (MEF2A alpha 1c isoform OS=Wuchereria bancrofti OX=6293 GN=WUBG_05386 PE=4 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 5.904e-39
Identity = 71/104 (68.27%), Postives = 89/104 (85.58%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDD 341
            MGRKKI+I +I+DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN+ NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ + A +++ES +  V SD+D
Sbjct:    1 MGRKKIQITRIQDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIME-ALQRKESKSGGVESDED 103
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Cavefish
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:103026245])

HSP 1 Score: 157.532 bits (397), Expect = 3.679e-41
Identity = 79/146 (54.11%), Postives = 99/146 (67.81%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDDI------SNELYYSRDNNIKQNENQAVESA 446
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD        ++L Y R   + + E++  +S 
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRTKGHSDCASPDPDDCFGHSPLMDDRFSKLNEESDLIYKRSAALNKKEHRGCDSP 143
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Cavefish
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:103026245])

HSP 1 Score: 156.762 bits (395), Expect = 6.074e-41
Identity = 79/146 (54.11%), Postives = 99/146 (67.81%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDDI------SNELYYSRDNNIKQNENQAVESA 446
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD        ++L Y R   + + E++  +S 
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRTKGHSDCASPDPDDCFGHSPLMDDRFSKLNEESDLIYKRSAALNKKEHRGCDSP 143
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Cavefish
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:103026245])

HSP 1 Score: 155.606 bits (392), Expect = 6.561e-41
Identity = 74/116 (63.79%), Postives = 87/116 (75.00%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDD 374
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRTKGHSDCASPDPDDCFGHSPLMDD 113
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Cavefish
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:103026245])

HSP 1 Score: 155.221 bits (391), Expect = 1.010e-40
Identity = 74/116 (63.79%), Postives = 87/116 (75.00%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDD 374
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRTKGHSDCASPDPDDCFGHSPLMDD 113
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Cavefish
Match: mef2d (myocyte enhancer factor 2D [Source:NCBI gene;Acc:103037494])

HSP 1 Score: 155.221 bits (391), Expect = 1.966e-40
Identity = 72/115 (62.61%), Postives = 88/115 (76.52%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   KK  +   +   D DD  +     DD
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCNSPEPDGDDSIDQSPLQDD 115
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Yeast
Match: SMP1 (MADS-box transcription factor involved in osmotic stress response; SMP1 has a paralog, RLM1, that arose from the whole genome duplication [Source:SGD;Acc:S000000386])

HSP 1 Score: 93.9745 bits (232), Expect = 5.938e-21
Identity = 41/66 (62.12%), Postives = 52/66 (78.79%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTIL 227
            MGR+KIEI+ IKD+R R VTF KRK+GL KKA+ELSVLC  +IA+II  +NN  Y+Y+S DM  +L
Sbjct:    1 MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSVDMSNLL 66
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Yeast
Match: RLM1 (MADS-box transcription factor; component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; RLM1 has a paralog, SMP1, that arose from the whole genome duplication [Source:SGD;Acc:S000006010])

HSP 1 Score: 94.7449 bits (234), Expect = 9.540e-21
Identity = 39/69 (56.52%), Postives = 53/69 (76.81%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRY 236
            MGR+KIEIQ+I D+R R VTF KRK+GL KKA+ELSVLC  +IA+II  +NN  Y+++S D + ++  Y
Sbjct:    1 MGRRKIEIQRISDDRNRAVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEFSSVDTNDLIYHY 69
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Yeast
Match: ARG80 (Transcription factor involved in regulating arginine-responsive genes; acts with Arg81p and Arg82p [Source:SGD;Acc:S000004645])

HSP 1 Score: 62.3882 bits (150), Expect = 8.065e-12
Identity = 27/68 (39.71%), Postives = 45/68 (66.18%), Query Frame = 3 
Query:   24 SLMGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTIL 227
            S + R+K  I+ I+++  R VTF+KR+ G+MKKAYELSVL    I L+I  N+  +Y + +  ++ ++
Sbjct:   76 STVTRRKQPIRYIENKTRRHVTFSKRRHGIMKKAYELSVLTGANILLLILANSGLVYTFTTPKLEPVV 143
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Yeast
Match: MCM1 (Transcription factor; involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000004646])

HSP 1 Score: 64.3142 bits (155), Expect = 9.702e-12
Identity = 26/64 (40.62%), Postives = 45/64 (70.31%), Query Frame = 3 
Query:   36 RKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTIL 227
            R+KIEI+ I+++  R VTF+KRK G+MKKA+ELSVL   ++ L++ +    +Y +++   + I+
Sbjct:   18 RRKIEIKFIENKTRRHVTFSKRKHGIMKKAFELSVLTGTQVLLLVVSETGLVYTFSTPKFEPIV 81
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Nematostella
Match: MEF2 (MADS-box transcription factor; Myocyte enhancer factor 2 splice variant IV; Predicted protein [Source:UniProtKB/TrEMBL;Acc:Q6S5H1])

HSP 1 Score: 149.058 bits (375), Expect = 1.494e-41
Identity = 67/91 (73.63%), Postives = 79/91 (86.81%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKK 302
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELS+LCDCEIALIIFN+ NKL+QYAS+DMD ILL+YT+Y EPHES+TN ++ +  SKK
Sbjct:    1 MGRKKIQISRIGDERNRQVTFTKRKFGLMKKAYELSILCDCEIALIIFNSANKLFQYASTDMDKILLKYTEYNEPHESRTNTDIVETISKK 91
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Nematostella
Match: EDO35636 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKX3])

HSP 1 Score: 110.538 bits (275), Expect = 1.524e-29
Identity = 49/60 (81.67%), Postives = 55/60 (91.67%), Query Frame = 3 
Query:   84 VTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHES 263
            VTF KRK GLMKKAYELS+LCDCEIALIIFN+ NKL+QYAS+DMD ILL+YT+Y EPHES
Sbjct:    1 VTFTKRKFGLMKKAYELSILCDCEIALIIFNSANKLFQYASTDMDKILLKYTEYNEPHES 60
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Nematostella
Match: EDO43028 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZP6])

HSP 1 Score: 59.6918 bits (143), Expect = 8.946e-11
Identity = 25/65 (38.46%), Postives = 43/65 (66.15%), Query Frame = 3 
Query:   33 GRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTIL 227
            GR KIE++ I ++  R  TF+KRK+G+MKKAYELS L   ++ L++ +    +Y +A+  +  ++
Sbjct:   34 GRVKIEMKFISNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVMLLVASETGHVYTFATRKLQPMI 98
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Medaka
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:101173054])

HSP 1 Score: 155.992 bits (393), Expect = 1.223e-40
Identity = 81/146 (55.48%), Postives = 100/146 (68.49%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDD----ISNE--LYYSRDNNIKQNENQAVESA 446
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD    +S E  L Y R   + + E++  +S 
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRNKGHNDCASPDPDDCFGHSPLMDDHFGKLSEESDLMYKRCGALNKKEHRGCDSP 143
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Medaka
Match: mef2d (myocyte-specific enhancer factor 2D homolog [Source:NCBI gene;Acc:101174373])

HSP 1 Score: 155.221 bits (391), Expect = 1.413e-40
Identity = 70/115 (60.87%), Postives = 90/115 (78.26%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDD 374
            MGRKKI+IQ+I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN ++ +   +K+    C     D+D+  +   ++D
Sbjct:    1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETL-RKKGFNGCNSPEPDNDDSIDQSPLND 114
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Medaka
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:101173054])

HSP 1 Score: 155.606 bits (392), Expect = 1.446e-40
Identity = 81/146 (55.48%), Postives = 100/146 (68.49%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDD----ISNE--LYYSRDNNIKQNENQAVESA 446
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD    +S E  L Y R   + + E++  +S 
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRNKGHNDCASPDPDDCFGHSPLMDDHFGKLSEESDLMYKRCGALNKKEHRGCDSP 143
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Medaka
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:101173054])

HSP 1 Score: 155.606 bits (392), Expect = 1.446e-40
Identity = 81/146 (55.48%), Postives = 100/146 (68.49%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDD----ISNE--LYYSRDNNIKQNENQAVESA 446
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD    +S E  L Y R   + + E++  +S 
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRNKGHNDCASPDPDDCFGHSPLMDDHFGKLSEESDLMYKRCGALNKKEHRGCDSP 143
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Medaka
Match: mef2aa (myocyte enhancer factor 2A [Source:NCBI gene;Acc:101173054])

HSP 1 Score: 156.377 bits (394), Expect = 1.450e-40
Identity = 81/145 (55.86%), Postives = 100/145 (68.97%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQE-MDD----ISNE--LYYSRDNNIKQNENQAVES 443
            MGRKKI+I +I DER RQVTF KRK GLMKKAYELSVLCDCEIALIIFN++NKL+QYAS+DMD +LL+YT+Y EPHES+TN    D+  K R   +    S D D+   H   MDD    +S E  L Y R   + + E++  +S
Sbjct:    1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNS---DIVEKLRNKGHNDCASPDPDDCFGHSPLMDDHFGKLSEESDLMYKRCGALNKKEHRGCDS 142
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Planmine SMEST
Match: SMESG000038141.1 (SMESG000038141.1)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 325/326 (99.69%), Postives = 325/326 (99.69%), Query Frame = 3 
Query:  498 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNGNNTFEVHSLNKSNNQXXXXXXXXXXXXXXXXXXXXLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLXXXXXXXXXXXXKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQSAESKRKWDSSGAASINQDQKPLKKA 1475
            MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNGNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQ AESKRKWDSSGAASINQDQKPLKKA
Sbjct:    1 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNGNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQCAESKRKWDSSGAASINQDQKPLKKA 326
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Planmine SMEST
Match: SMESG000038141.1 (SMESG000038141.1)

HSP 1 Score: 574.318 bits (1479), Expect = 0.000e+0
Identity = 325/328 (99.09%), Postives = 325/328 (99.09%), Query Frame = 3 
Query:  498 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKN--GNNTFEVHSLNKSNNQXXXXXXXXXXXXXXXXXXXXLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLXXXXXXXXXXXXKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQSAESKRKWDSSGAASINQDQKPLKKA 1475
            MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKN  GNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQ AESKRKWDSSGAASINQDQKPLKKA
Sbjct:    1 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNVLGNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQCAESKRKWDSSGAASINQDQKPLKKA 328
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Planmine SMEST
Match: SMESG000038141.1 (SMESG000038141.1)

HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0
Identity = 320/326 (98.16%), Postives = 320/326 (98.16%), Query Frame = 3 
Query:  498 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNGNNTFEVHSLNKSNNQXXXXXXXXXXXXXXXXXXXXLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLXXXXXXXXXXXXKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQSAESKRKWDSSGAASINQDQKPLKKA 1475
            MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQN     APFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNGNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQ AESKRKWDSSGAASINQDQKPLKKA
Sbjct:    1 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQN-----APFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNGNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQCAESKRKWDSSGAASINQDQKPLKKA 321
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Planmine SMEST
Match: SMESG000038141.1 (SMESG000038141.1)

HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0
Identity = 320/328 (97.56%), Postives = 320/328 (97.56%), Query Frame = 3 
Query:  498 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQNYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKN--GNNTFEVHSLNKSNNQXXXXXXXXXXXXXXXXXXXXLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLXXXXXXXXXXXXKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQSAESKRKWDSSGAASINQDQKPLKKA 1475
            MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQN     APFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKN  GNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQ AESKRKWDSSGAASINQDQKPLKKA
Sbjct:    1 MFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQN-----APFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDSSFLNLKNVLGNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPILPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTVGPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSYDLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQNIKSIQCAESKRKWDSSGAASINQDQKPLKKA 323
[Close]
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Planmine SMEST
Match: SMESG000040479.1 (SMESG000040479.1)

HSP 1 Score: 324.324 bits (830), Expect = 1.379e-108
Identity = 156/157 (99.36%), Postives = 157/157 (100.00%), Query Frame = 3 
Query:   30 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDDISNELYYSRDNNIKQNENQAVESAHGLMNRNEESIIRISPGM 500
            MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDDISNELYYSRDNNIKQNENQAVESAHGLMNRNEESIIRISPG+
Sbjct:    1 MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNNNNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVNSDDDDEDENHQEMDDISNELYYSRDNNIKQNENQAVESAHGLMNRNEESIIRISPGV 157
The following BLAST results are available for this feature:
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MEF2D5.226e-4173.63myocyte enhancer factor 2D [Source:HGNC Symbol;Acc... [more]
MEF2D5.226e-4173.63myocyte enhancer factor 2D [Source:HGNC Symbol;Acc... [more]
MEF2C1.355e-4067.62myocyte enhancer factor 2C [Source:HGNC Symbol;Acc... [more]
MEF2C1.376e-4067.62myocyte enhancer factor 2C [Source:HGNC Symbol;Acc... [more]
MEF2C1.486e-4067.62myocyte enhancer factor 2C [Source:HGNC Symbol;Acc... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mef-21.506e-4066.35Related to vertebrate MEF2 transcription factor [... [more]
unc-1201.901e-936.92pep chromosome:WBcel235:I:8460225:8463015:1 gene:W... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mef24.143e-3776.19gene:FBgn0011656 transcript:FBtr0088446[more]
Mef24.531e-3776.19gene:FBgn0011656 transcript:FBtr0088445[more]
Mef24.862e-3776.19gene:FBgn0011656 transcript:FBtr0088444[more]
Mef24.909e-3776.19gene:FBgn0011656 transcript:FBtr0088447[more]
Mef26.430e-3776.19gene:FBgn0011656 transcript:FBtr0330707[more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mef2ab7.750e-4172.73myocyte enhancer factor 2ab [Source:ZFIN;Acc:ZDB-G... [more]
mef2ab7.750e-4172.73myocyte enhancer factor 2ab [Source:ZFIN;Acc:ZDB-G... [more]
mef2ca1.440e-4076.19myocyte enhancer factor 2ca [Source:ZFIN;Acc:ZDB-G... [more]
mef2ca1.440e-4076.19myocyte enhancer factor 2ca [Source:ZFIN;Acc:ZDB-G... [more]
mef2ca1.440e-4076.19myocyte enhancer factor 2ca [Source:ZFIN;Acc:ZDB-G... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mef2a1.374e-4072.53myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2d1.590e-4062.61myocyte enhancer factor 2D [Source:NCBI gene;Acc:7... [more]
mef2a1.822e-4072.53myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2d2.077e-4062.61myocyte enhancer factor 2D [Source:NCBI gene;Acc:7... [more]
mef2d3.111e-4062.61myocyte enhancer factor 2D [Source:NCBI gene;Acc:7... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mef2a3.090e-4161.74myocyte enhancer factor 2A [Source:MGI Symbol;Acc:... [more]
Mef2c4.420e-4172.53myocyte enhancer factor 2C [Source:MGI Symbol;Acc:... [more]
Mef2c9.993e-4172.53myocyte enhancer factor 2C [Source:MGI Symbol;Acc:... [more]
Mef2c1.386e-4072.53myocyte enhancer factor 2C [Source:MGI Symbol;Acc:... [more]
Mef2c1.475e-4072.53myocyte enhancer factor 2C [Source:MGI Symbol;Acc:... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q03414|MEF2A_XENLA1.065e-3952.08Myocyte-specific enhancer factor 2A homolog OS=Xen... [more]
sp|Q03413|MEF2D_XENLA2.067e-3962.61Myocyte-specific enhancer factor 2D homolog OS=Xen... [more]
sp|O89038|MEF2D_RAT2.825e-3961.74Myocyte-specific enhancer factor 2D OS=Rattus norv... [more]
sp|Q63943|MEF2D_MOUSE3.627e-3961.74Myocyte-specific enhancer factor 2D OS=Mus musculu... [more]
sp|Q14814|MEF2D_HUMAN4.689e-3961.74Myocyte-specific enhancer factor 2D OS=Homo sapien... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3Q5I52.398e-4068.27MADS-box domain-containing protein OS=Brugia timor... [more]
A0A087UPT22.923e-3965.45Myocyte-specific enhancer factor 2A (Fragment) OS=... [more]
T1KCI54.291e-3939.11MADS-box domain-containing protein OS=Tetranychus ... [more]
A0A1I8CM094.642e-3967.31MADS-box domain-containing protein OS=Rhabditophan... [more]
J9F2L75.904e-3968.27MEF2A alpha 1c isoform OS=Wuchereria bancrofti OX=... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mef2aa3.679e-4154.11myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2aa6.074e-4154.11myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2aa6.561e-4163.79myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2aa1.010e-4063.79myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2d1.966e-4062.61myocyte enhancer factor 2D [Source:NCBI gene;Acc:1... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
SMP15.938e-2162.12MADS-box transcription factor involved in osmotic ... [more]
RLM19.540e-2156.52MADS-box transcription factor; component of the pr... [more]
ARG808.065e-1239.71Transcription factor involved in regulating argini... [more]
MCM19.702e-1240.63Transcription factor; involved in cell-type-specif... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
MEF21.494e-4173.63MADS-box transcription factor; Myocyte enhancer fa... [more]
EDO356361.524e-2981.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO430288.946e-1138.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mef2aa1.223e-4055.48myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2d1.413e-4060.87myocyte-specific enhancer factor 2D homolog [Sourc... [more]
mef2aa1.446e-4055.48myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2aa1.446e-4055.48myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
mef2aa1.450e-4055.86myocyte enhancer factor 2A [Source:NCBI gene;Acc:1... [more]
back to top
BLAST of Myocyte-specific enhancer factor 2A homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000038141.10.000e+099.69SMESG000038141.1[more]
SMESG000038141.10.000e+099.09SMESG000038141.1[more]
SMESG000038141.10.000e+098.16SMESG000038141.1[more]
SMESG000038141.10.000e+097.56SMESG000038141.1[more]
SMESG000040479.11.379e-10899.36SMESG000040479.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031794 ID=SMED30031794|Name=Myocyte-specific enhancer factor 2A homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=1866bp
AATCTATATAAATCTTATATGATTCTTTAATGGGAAGAAAAAAGATAGAA
ATACAGAAAATCAAAGATGAAAGAACTAGACAGGTGACATTTGCTAAACG
GAAATCCGGTTTGATGAAGAAAGCATACGAGCTAAGTGTTCTGTGTGATT
GCGAAATTGCCTTAATTATATTCAATAATAATAACAAACTATACCAGTAT
GCCAGTTCTGACATGGACACAATTCTGTTACGTTATACGCAATACGAAGA
GCCACACGAATCAAAAACAAACAAAGAATTGCATGATGTTGCATCAAAAA
AACGTGAAAGTACCAATTGCACAGTTAATTCAGATGACGATGACGAAGAT
GAGAACCATCAAGAAATGGATGATATCTCAAACGAGTTGTATTATTCAAG
GGATAATAATATAAAACAAAATGAAAATCAGGCTGTTGAATCAGCACATG
GACTTATGAATAGGAACGAGGAATCCATAATCCGCATTTCACCTGGGATG
TTTTATAATTCTACTGATGGCGATGCTGGAAATACGGAGCAATCGAATTC
TATTGACCCTCACCAGTATATTTTTATTACTTCAGAAGACGCGAATCTTA
TGAATCTCGTTTTACCAAATCAAAATCAAAACTATATAGATGCGCCATTC
CAATCTGCGGAATTATTGGACAAACAATCGGGTTTGTCGTCAATCGTTTT
GCAGCAAGGAAATATGGGGAAATCAGATACTCCACAGGCAGAATCATTCT
TAATAGTTTCCAATGCCAATTTGGATTCATCTTTTTTAAATTTGAAAAAC
GGAAACAATACTTTTGAGGTTCATAGTCTGAACAAATCAAATAATCAGTC
ATTGGAATCGAAGACAGATTCGATCTCTGATAGTAGCATGTCATACAATA
AAAAGTCTTTAGCGCCGAAGGTTCCTATTTTACCATATCAACCTTTAACA
CACAACCGAAATTTCAAGCAAGAAAAAGTGGATACGAAAATCTCTATGAA
AAAGTCCAATCATCTGCCAAGGCCAACTACATTCCCTAGAATAACTATTC
CCAAACAGTGTGATGTTATTGATACAGTAGGGCCCTCGAGTTCTTTTCTA
AACACCCCTGATGTTATTAATACTCTTGAGACTTTAGATTCGTCCAATAA
ACAGAATAATGCCTCGATGAAATCGAACATATCACTAGTGAACAACACTT
TCTCTCTTTCTAATGCTATGGATAGTTATGATTTACGAACTCATGCTAAA
TCAAATTTAATGTCAGATTCATCAGATATAGACCTTATTAATCAACCTTC
CCCTTTATTATCCAACTTCAATCCTATGCCACATATTGTTTCATCACATT
CAGTTTCTGCTACAAATATGAACATACAAAATATTAAATCTATTCAAAGT
GCTGAGTCTAAAAGAAAATGGGACTCTTCAGGTGCTGCCTCAATTAACCA
AGATCAGAAGCCTTTAAAAAAGGCATCTTTAGATAATTCCGATAATTCTT
AACTATCTAGATTTTTTATGATAATCTTCATACACTATTTTAAAATAGAT
TTAACGTTTTTCAGATTTTCACCCAATTGAAACTGACGTTGTGTATTGCG
CTTGCATAATTACTTTCTTATTGACTTCATCAAAATTAGTCTAATTTTAA
AGTTTTATTAAACGGATTATTATTCGCTTCAATATAATGTGTATTAGAAA
CGGGATATGTATATAATATGCATCTTTATTCGGTATTTTATTATTTAAAT
GGTACAAAAGGTTCATAATCGAGTATGAAACAAATTGAATATCGTTGATA
AATTATTTTGTTTTATATTTTGAATATTAACTCAAATGGTGCAGTTCATT
ACATTTCCATGGTCAA
back to top

protein sequence of SMED30031794-orf-1

>SMED30031794-orf-1 ID=SMED30031794-orf-1|Name=SMED30031794-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=491bp
MGRKKIEIQKIKDERTRQVTFAKRKSGLMKKAYELSVLCDCEIALIIFNN
NNKLYQYASSDMDTILLRYTQYEEPHESKTNKELHDVASKKRESTNCTVN
SDDDDEDENHQEMDDISNELYYSRDNNIKQNENQAVESAHGLMNRNEESI
IRISPGMFYNSTDGDAGNTEQSNSIDPHQYIFITSEDANLMNLVLPNQNQ
NYIDAPFQSAELLDKQSGLSSIVLQQGNMGKSDTPQAESFLIVSNANLDS
SFLNLKNGNNTFEVHSLNKSNNQSLESKTDSISDSSMSYNKKSLAPKVPI
LPYQPLTHNRNFKQEKVDTKISMKKSNHLPRPTTFPRITIPKQCDVIDTV
GPSSSFLNTPDVINTLETLDSSNKQNNASMKSNISLVNNTFSLSNAMDSY
DLRTHAKSNLMSDSSDIDLINQPSPLLSNFNPMPHIVSSHSVSATNMNIQ
NIKSIQSAESKRKWDSSGAASINQDQKPLKKASLDNSDNS*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0007275multicellular organism development
GO:0009952anterior/posterior pattern specification
GO:0000165MAPK cascade
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0045944positive regulation of transcription from RNA polymerase II promoter
Vocabulary: molecular function
TermDefinition
GO:0019901protein kinase binding
GO:0043565sequence-specific DNA binding
GO:0046983protein dimerization activity
GO:0003677DNA binding
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR002100TF_MADSbox
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 238..262
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 235..262
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 41..60