Jagged-like
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031788 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 18Note: Hover over icons to view figure legend
Homology
BLAST of Jagged-like vs. Ensembl Human
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]) HSP 1 Score: 65.855 bits (159), Expect = 1.966e-10 Identity = 38/96 (39.58%), Postives = 54/96 (56.25%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C E+ C N GTC+ G ++ KC C DG+ G CE + C++ C NGG C +L NDF C CKN + GK+C C++ TC C
Sbjct: 629 NINDC--ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC--RDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTC 720 HSP 2 Score: 54.6842 bits (130), Expect = 4.629e-7 Identity = 47/166 (28.31%), Postives = 68/166 (40.96%), Query Frame = 1
Query: 478 IHSQDFATLSVDIVIKCKPGFFPKN------RCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIV 954
++++ L C PG+ +N CL C +AS R IC GY D ++D C S C N G C + + +C C GFSG C++ D C C+NG +C +D+ C C +Y GK+C C CE C +
Sbjct: 422 VNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCER--DIDECASN--PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNR--ASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVA 581
BLAST of Jagged-like vs. Ensembl Human
Match: VCAN (versican [Source:HGNC Symbol;Acc:HGNC:2464]) HSP 1 Score: 64.3142 bits (155), Expect = 4.921e-10 Identity = 33/96 (34.38%), Postives = 46/96 (47.92%), Query Frame = 1
Query: 631 YVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCN 915
Y+ + NK D C C N GTC + C CV G+SG CE+ +D C C+NG C+ N F C C +Y G CE+ ++C+
Sbjct: 1277 YIIEVRENKTGPDRCKMNP--CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDG--FNTFRCLCLPSYVGALCEQDTETCD 1368
BLAST of Jagged-like vs. Ensembl Human
Match: VCAN (versican [Source:HGNC Symbol;Acc:HGNC:2464]) HSP 1 Score: 64.3142 bits (155), Expect = 5.077e-10 Identity = 33/96 (34.38%), Postives = 46/96 (47.92%), Query Frame = 1
Query: 631 YVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCN 915
Y+ + NK D C C N GTC + C CV G+SG CE+ +D C C+NG C+ N F C C +Y G CE+ ++C+
Sbjct: 1325 YIIEVRENKTGPDRCKMNP--CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDG--FNTFRCLCLPSYVGALCEQDTETCD 1416
BLAST of Jagged-like vs. Ensembl Human
Match: NOTCH1 (notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881]) HSP 1 Score: 64.3142 bits (155), Expect = 5.267e-10 Identity = 38/123 (30.89%), Postives = 56/123 (45.53%), Query Frame = 1
Query: 625 SGYV------FDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
SGYV F + N++ C S C N GTC+ KC C+ ++G +CE+ PC C+NGG+C +SE F C C + G++CE C C C+ + +C
Sbjct: 773 SGYVCTCREGFSGPNCQTNINECASNP--CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRC 893 HSP 2 Score: 59.3066 bits (142), Expect = 1.971e-8 Identity = 37/122 (30.33%), Postives = 55/122 (45.08%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITC 927
+C ++ ++C IC+ GY + + + N D C S C +NG C+ + +C C GF+G C+ D C CKNG KC+ N + C C Y G CE C+ C
Sbjct: 466 TCLDQIGEFQC------ICMPGY--EGVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPC 575 HSP 3 Score: 57.3806 bits (137), Expect = 8.408e-8 Identity = 43/152 (28.29%), Postives = 61/152 (40.13%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCN------SENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSF 999
+C + + YKC C G + + N+D+CN S + CFNNGTCV C C GF G CE + C C G + NDF C C+ + G+ CE C C+ C + +N + + K F
Sbjct: 1197 TCLDLPNTYKCS------CPRGT--QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340 HSP 4 Score: 55.4546 bits (132), Expect = 3.291e-7 Identity = 32/91 (35.16%), Postives = 44/91 (48.35%), Query Frame = 1
Query: 643 PLTNKCNLDNCNSENIICFNNGTC-VSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSC 912
PL N C + C N GTC + KC C G+SG SC+ DPC C NGG+C+ E +IC C +++G +C + C
Sbjct: 101 PLDNACLTNPCR-------NGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEAS--YICHCPPSFHGPTCRQDVNEC 182 HSP 5 Score: 54.6842 bits (130), Expect = 6.030e-7 Identity = 43/157 (27.39%), Postives = 65/157 (41.40%), Query Frame = 1
Query: 526 CKPGFFPK------NRCLVS-CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
C PGF N C C A+ C ++ C +G F + + N +C + CFN GTCV G ++ C C GF+G C+ + C C +GG C + + C C Y G +C+ C+ C+ C + Q +C
Sbjct: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAG--FSGIHCENNTPDCTESS--CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTC--QDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRC 1083 HSP 6 Score: 54.299 bits (129), Expect = 7.590e-7 Identity = 37/126 (29.37%), Postives = 57/126 (45.24%), Query Frame = 1
Query: 604 NGRKICL--SGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
NG+ IC SGY + ++D C+ C + G C++ + +C C+ G++GP CEI + C C+N C+ + +F C C Y G CE C C N C N+ +C
Sbjct: 393 NGKAICTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL--DQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQC 514 HSP 7 Score: 53.1434 bits (126), Expect = 1.635e-6 Identity = 37/134 (27.61%), Postives = 56/134 (41.79%), Query Frame = 1
Query: 550 NRCLVS-CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N C++S C AS R C +GY + ++D+C C N G+C G + C C+ GF G C E + C C+NG C ++ + + C C + G CE C + +C C
Sbjct: 871 NECVLSPCRHGASCQNTHGGYRCHCQAGY--SGRNCETDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC--TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC 998 HSP 8 Score: 51.9878 bits (123), Expect = 3.316e-6 Identity = 34/141 (24.11%), Postives = 55/141 (39.01%), Query Frame = 1
Query: 568 CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI------WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
C ++ + ++C+ C +G+ + C D + C N C+ G + C C +G++G CE+ DPC CK+G F C C+ Y G CE C+ C C+ +N C
Sbjct: 505 CLDKINEFQCE------CPTGFT----GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVAT--------FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLC 627 HSP 9 Score: 51.9878 bits (123), Expect = 3.550e-6 Identity = 28/102 (27.45%), Postives = 47/102 (46.08%), Query Frame = 1
Query: 691 ICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSK 993
+C + G CV + C C G++G CE + D C+ C+NG C ++ + C C Y+G +C + C C+ C + N KCS + ++
Sbjct: 1115 LCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC--TDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQ 1214
BLAST of Jagged-like vs. Ensembl Human
Match: SNED1 (sushi, nidogen and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:24696]) HSP 1 Score: 63.5438 bits (153), Expect = 8.265e-10 Identity = 43/140 (30.71%), Postives = 65/140 (46.43%), Query Frame = 1
Query: 550 NRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKND-FICFCKNNYYGKSCEKTGKSCNDITCEKNQFC-EIVNN 960
+C+ C Y C CLSG+ +C+LD + C N GTC G ++ +C C GF GP+CE PC C++GG+C +++N +C C+ Y G +CE C+ C C ++V N
Sbjct: 282 GKCIDDCVTGNPSYTCS------CLSGFT----GRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQC---QVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGN 408 HSP 2 Score: 53.1434 bits (126), Expect = 1.358e-6 Identity = 33/124 (26.61%), Postives = 54/124 (43.55%), Query Frame = 1
Query: 601 ENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-----IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVN 957
ENG +C+ + + ++D+C+ + C N G+CV N C C + F G CE + D C C NGG C+ ++ ++C C + G C + + +D C C N
Sbjct: 367 ENGSAVCVCQAGYTGAACEMDVDDCSPDP--CLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD--QGYVCECPEGFMGLDCRE--RVPDDCECRNGGRCLGAN 484 HSP 3 Score: 51.9878 bits (123), Expect = 3.332e-6 Identity = 32/78 (41.03%), Postives = 38/78 (48.72%), Query Frame = 1
Query: 667 DNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIW-DPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEK 897
D+C S C N GTC KC C GFSG CEI PC + C NGG C + DF C C+ Y G+ C+
Sbjct: 621 DSCASGP--CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTC--EDRDTDFFCHCQAGYMGRRCQA 694 HSP 4 Score: 51.6026 bits (122), Expect = 4.494e-6 Identity = 31/113 (27.43%), Postives = 47/113 (41.59%), Query Frame = 1
Query: 613 KICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCE 948
++C V+ +D C S+ C + G+C C C G+ G CE+ D C C+NGG C L ++C C + G CE +C+ C+ CE
Sbjct: 737 RVCQPHGVWSEPPQCLEIDECRSQP--CLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSC--RNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCE 845
BLAST of Jagged-like vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 61.6178 bits (148), Expect = 1.740e-9 Identity = 35/91 (38.46%), Postives = 49/91 (53.85%), Query Frame = 1
Query: 673 CNSENIICFNNGTCVS-GAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDI-TCEKN 936
CN ++ C + GTC+S G + KC C +SG CEI +PC C G +CI ND++C C N + GK CE G ++ +C KN
Sbjct: 3933 CN--DLPCQHAGTCISQGKSHFKCECPSRYSGNVCEIDLEPCASSPCPTGIQCIP--FYNDYLCKCPNGFTGKHCEARGFEDHETSSCSKN 4019
BLAST of Jagged-like vs. Ensembl Celegans
Match: clec-78 (C-type LECtin [Source:UniProtKB/TrEMBL;Acc:Q20531]) HSP 1 Score: 58.9214 bits (141), Expect = 1.170e-8 Identity = 52/162 (32.10%), Postives = 72/162 (44.44%), Query Frame = 1
Query: 526 CKPGFFPKNRCLV--------SCFEEASVYKCDENGRKI-CLSGYVFDPLTNKCNLDNCNSENIICFNNGTC--VSGAHNPKCFCVDGFSGPSCE-IWDPC-TKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
CKPG+ +RC + C+ KC++ G C +F+ + D CN + C N G C + G + C C GF+GP CE I D C T C+NG +CI +L F C C + G +C+K C D C N C + N KC
Sbjct: 2039 CKPGYV-GDRCEMLEDVCSTQPCYNGG---KCEQVGTTYKCTCPKMFNGARCQFESDECN--GVKCPNGGVCHDLPGVKSTTCLCRTGFAGPQCEEITDICSTNNPCRNGARCIGEKLGR-FKCQCVPGWEGPNCDKNIDDCADSPCALNATCVDLINDYKC 2193 HSP 2 Score: 55.0694 bits (131), Expect = 1.775e-7 Identity = 52/169 (30.77%), Postives = 68/169 (40.24%), Query Frame = 1
Query: 511 DIVIKCKPGF------FPKNRCLVS-------CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC-EIVNNQPKC 972
D CKPG+ +++C S C + YKC +C SG+ KC DN + C NNG CVS + C C G SG +CE + C C NGG+C + + C C ++ GK CE C TCE C E KC
Sbjct: 2343 DFKCVCKPGYTGPRCDVKQDQCADSPCLNDAQCVDMGGAYKC------VCKSGWT----GPKCEQDNGSCAAKPCRNNGFCVSLVADYFCVCPPGVSGKNCESAPNRCIGQPCHNGGEC--GDFGSHLECACPASFTGKGCEFKNTGCK--TCENGGKCAEAAGGLQKC 2497 HSP 3 Score: 51.9878 bits (123), Expect = 1.359e-6 Identity = 47/166 (28.31%), Postives = 67/166 (40.36%), Query Frame = 1
Query: 526 CKPGFFPKN------RCLVS-------CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVK 981
C+PG+ +N C S C +E + Y C+ C GY + + + +D+C + C NN TC + C C GF G CE+ D C + +C G + NDF C CK Y G C+ C D C + C + KC K
Sbjct: 2232 CQPGWTGENCDQNIDECAASPCQNDAKCIDEINGYMCE------CADGY--EGVHCQHLVDHCAKQP--CHNNATCTNMGATYHCDCTLGFDGVHCEMNIDECAENQCDKLGTESCRDAVNDFKCVCKPGYTGPRCDVKQDQCADSPCLNDAQCVDMGGAYKCVCK 2387 HSP 4 Score: 51.6026 bits (122), Expect = 1.878e-6 Identity = 37/138 (26.81%), Postives = 56/138 (40.58%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWD-PCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCS 975
SC + + +KC +C GY +C++ + C N+ CV KC C G++GP CE + C C+N G C+ L D+ C C GK+CE C C C + +C+
Sbjct: 2336 SCRDAVNDFKC------VCKPGYT----GPRCDVKQDQCADSPCLNDAQCVDMGGAYKCVCKSGWTGPKCEQDNGSCAAKPCRNNGFCVS--LVADYFCVCPPGVSGKNCESAPNRCIGQPCHNGGECGDFGSHLECA 2461 HSP 5 Score: 49.2914 bits (116), Expect = 9.790e-6 Identity = 27/86 (31.40%), Postives = 38/86 (44.19%), Query Frame = 1
Query: 691 ICFNNGTCVSGAHNPKCFCVDGFSGPSCEIW-DPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
+C NN C H +C C G+ G CE+ D C+ C NGGKC ++ + C C + G C+ CN + C C
Sbjct: 2021 MCENNAECSVFMHRAQCHCKPGYVGDRCEMLEDVCSTQPCYNGGKC--EQVGTTYKCTCPKMFNGARCQFESDECNGVKCPNGGVC 2104
BLAST of Jagged-like vs. Ensembl Celegans
Match: ZC116.3 (Probable cubilin [Source:UniProtKB/Swiss-Prot;Acc:Q20911]) HSP 1 Score: 55.4546 bits (132), Expect = 1.328e-7 Identity = 41/127 (32.28%), Postives = 59/127 (46.46%), Query Frame = 1
Query: 547 KNRC--LVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNS--ENIICFNNGTCVSGAHNP-KCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSC 912
KN+C L +C Y + C GYV D + + + + ++ +N C N G C + KC C GF G CE PC CKNGG CI E N C C +++G++CE+ + C
Sbjct: 394 KNKCHKLATCKVTDDGYSAVGDYTCYCPDGYVGDGIGEEGCVKSASNVCQNHNCVNAGKCKPTSDTEYKCECEAGFLGKFCEKTSPCQTNPCKNGGTCIAVE--NSAYCDCPEHFFGRACEEEEEHC 518
BLAST of Jagged-like vs. Ensembl Celegans
Match: slt-1 (Slit homolog 1 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EFX6]) HSP 1 Score: 55.0694 bits (131), Expect = 1.514e-7 Identity = 34/108 (31.48%), Postives = 52/108 (48.15%), Query Frame = 1
Query: 604 NGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI----------WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEK 897
NG C+ F + N+D+C +N+ C N G+CV G + C C G++G CEI D C + C G+C+ S+ +DF C C + G SC++
Sbjct: 1006 NGSYSCMCSPGFTGNNCETNIDDC--KNVECQNGGSCVDGILSYDCLCRPGYAGQYCEIPPMMDMEYQKTDACQQSACGQ-GECVASQNSSDFTCKCHEGFSGPSCDR 1110 HSP 2 Score: 51.9878 bits (123), Expect = 1.316e-6 Identity = 35/104 (33.65%), Postives = 48/104 (46.15%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC-EIVNNQPKCSVKKNSKSF 999
C NNG C+ + C C GF+G +CE D C C+NGG C+ L D C C+ Y G+ CE D+ +K C + Q +C +NS F
Sbjct: 996 CENNGKCIPINGSYSCMCSPGFTGNNCETNIDDCKNVECQNGGSCVDGILSYD--CLCRPGYAGQYCEIPPMM--DMEYQKTDACQQSACGQGECVASQNSSDF 1095
BLAST of Jagged-like vs. Ensembl Celegans
Match: crb-1 (Drosophila CRumBs homolog [Source:UniProtKB/TrEMBL;Acc:Q19350]) HSP 1 Score: 55.0694 bits (131), Expect = 1.522e-7 Identity = 38/112 (33.93%), Postives = 60/112 (53.57%), Query Frame = 1
Query: 604 NGRK-ICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIW-DPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKS-CNDITCE 930
N RK +C +G+ + + N+++C + + C +G C+ G KC C +GF G CE+ D C C NGGKC+K+ + +C C N++ G SC T + C D C+
Sbjct: 1194 NKRKCVCPAGFAGENCED--NVNDC--KFVDCGKHGYCLDGIDEAKCICNNGFHGEHCELAKDECEGVECHNGGKCVKNRSEK-IVCQCGNSWMGDSCNVTKTTNCKDSPCQ 1300 HSP 2 Score: 49.6766 bits (117), Expect = 6.561e-6 Identity = 35/86 (40.70%), Postives = 41/86 (47.67%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCE-KTGKSCNDITCEKNQFC 945
C NNGTCV+ N KC C GF G CE D C + C+NG C LK + C C + GK CE + K C C N C
Sbjct: 134 CQNNGTCVAENGNVKCACPPGFVGDHCETDEDECKENFCQNGADC--ENLKGSYECKCLKGFSGKYCEIQDKKQCTSDYCHNNGQC 217
BLAST of Jagged-like vs. Ensembl Fly
Match: eys (gene:FBgn0031414 transcript:FBtr0344662) HSP 1 Score: 64.3142 bits (155), Expect = 2.962e-10 Identity = 44/129 (34.11%), Postives = 55/129 (42.64%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTN---KCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQ 939
+C V+ +G S Y D T + N D C S C N GTCV G C C +GFSG +C E D C C+NGG C + N +IC C+ Y G CE C T + Q
Sbjct: 147 ACLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSP--CQNGGTCVDGVAYYNCTCPEGFSGSNCEENVDECMSNPCQNGGLC--RDRTNGYICTCQPGYLGSHCELDVAVCETGTGARCQ 271 HSP 2 Score: 60.077 bits (144), Expect = 6.538e-9 Identity = 29/102 (28.43%), Postives = 47/102 (46.08%), Query Frame = 1
Query: 694 CFNN----GTCVSGAHNP-KCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVK 981
C +N G C+ G ++ C+C+DG++G C+ WD C C+NGG C+ + C C + G +CE+ C C+ C N C+ +
Sbjct: 148 CLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSPCQNGGTCVDGVAY--YNCTCPEGFSGSNCEENVDECMSNPCQNGGLCRDRTNGYICTCQ 247 HSP 3 Score: 51.6026 bits (122), Expect = 2.057e-6 Identity = 35/131 (26.72%), Postives = 55/131 (41.98%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE----IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
+C + + Y C C G F + N+D C S C N G C + C C G+ G CE + + T RC++GG+CI+ +F C C ++G+ C++ C C+ C
Sbjct: 196 TCVDGVAYYNC------TCPEG--FSGSNCEENVDECMSNP--CQNGGLCRDRTNGYICTCQPGYLGSHCELDVAVCETGTGARCQHGGECIEGP-GLEFTCDCPAGWHGRICQEEINECASSPCQNGGVC 315 HSP 4 Score: 51.2174 bits (121), Expect = 2.795e-6 Identity = 31/82 (37.80%), Postives = 37/82 (45.12%), Query Frame = 1
Query: 670 NCNSENIICF-----NNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCT-KPRCKNGGKCIKSELKNDFICFCKNNYYGKSCE 894
NC E +IC NN C+ P C+CV + G CE +D C PRC NGG CI + F C C G CE
Sbjct: 334 NCEEEILICADNPCQNNALCLMEEGVPTCYCVPDYHGEKCEFQYDECQLGPRCMNGGVCIDG--VDTFSCSCPPLLTGMLCE 413 HSP 5 Score: 50.447 bits (119), Expect = 5.252e-6 Identity = 40/140 (28.57%), Postives = 54/140 (38.57%), Query Frame = 1
Query: 568 CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSEN---IICFNNGTCVSG-AHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
C + + Y C C GY L + C LD E C + G C+ G C C G+ G C E + C C+NGG C+ + C C Y G +CE+ C D C+ N C + P C
Sbjct: 235 CRDRTNGYIC------TCQPGY----LGSHCELDVAVCETGTGARCQHGGECIEGPGLEFTCDCPAGWHGRICQEEINECASSPCQNGGVCVDKLAA--YACACPMGYTGINCEEEILICADNPCQNNALCLMEEGVPTC 362
BLAST of Jagged-like vs. Ensembl Fly
Match: eys (gene:FBgn0031414 transcript:FBtr0344663) HSP 1 Score: 64.3142 bits (155), Expect = 2.962e-10 Identity = 44/129 (34.11%), Postives = 55/129 (42.64%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTN---KCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQ 939
+C V+ +G S Y D T + N D C S C N GTCV G C C +GFSG +C E D C C+NGG C + N +IC C+ Y G CE C T + Q
Sbjct: 147 ACLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSP--CQNGGTCVDGVAYYNCTCPEGFSGSNCEENVDECMSNPCQNGGLC--RDRTNGYICTCQPGYLGSHCELDVAVCETGTGARCQ 271 HSP 2 Score: 60.077 bits (144), Expect = 6.538e-9 Identity = 29/102 (28.43%), Postives = 47/102 (46.08%), Query Frame = 1
Query: 694 CFNN----GTCVSGAHNP-KCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVK 981
C +N G C+ G ++ C+C+DG++G C+ WD C C+NGG C+ + C C + G +CE+ C C+ C N C+ +
Sbjct: 148 CLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSPCQNGGTCVDGVAY--YNCTCPEGFSGSNCEENVDECMSNPCQNGGLCRDRTNGYICTCQ 247 HSP 3 Score: 51.6026 bits (122), Expect = 2.057e-6 Identity = 35/131 (26.72%), Postives = 55/131 (41.98%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE----IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
+C + + Y C C G F + N+D C S C N G C + C C G+ G CE + + T RC++GG+CI+ +F C C ++G+ C++ C C+ C
Sbjct: 196 TCVDGVAYYNC------TCPEG--FSGSNCEENVDECMSNP--CQNGGLCRDRTNGYICTCQPGYLGSHCELDVAVCETGTGARCQHGGECIEGP-GLEFTCDCPAGWHGRICQEEINECASSPCQNGGVC 315 HSP 4 Score: 51.2174 bits (121), Expect = 2.795e-6 Identity = 31/82 (37.80%), Postives = 37/82 (45.12%), Query Frame = 1
Query: 670 NCNSENIICF-----NNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCT-KPRCKNGGKCIKSELKNDFICFCKNNYYGKSCE 894
NC E +IC NN C+ P C+CV + G CE +D C PRC NGG CI + F C C G CE
Sbjct: 334 NCEEEILICADNPCQNNALCLMEEGVPTCYCVPDYHGEKCEFQYDECQLGPRCMNGGVCIDG--VDTFSCSCPPLLTGMLCE 413 HSP 5 Score: 50.447 bits (119), Expect = 5.252e-6 Identity = 40/140 (28.57%), Postives = 54/140 (38.57%), Query Frame = 1
Query: 568 CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSEN---IICFNNGTCVSG-AHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
C + + Y C C GY L + C LD E C + G C+ G C C G+ G C E + C C+NGG C+ + C C Y G +CE+ C D C+ N C + P C
Sbjct: 235 CRDRTNGYIC------TCQPGY----LGSHCELDVAVCETGTGARCQHGGECIEGPGLEFTCDCPAGWHGRICQEEINECASSPCQNGGVCVDKLAA--YACACPMGYTGINCEEEILICADNPCQNNALCLMEEGVPTC 362
BLAST of Jagged-like vs. Ensembl Fly
Match: wry (gene:FBgn0051665 transcript:FBtr0089786) HSP 1 Score: 59.3066 bits (142), Expect = 8.320e-9 Identity = 35/98 (35.71%), Postives = 42/98 (42.86%), Query Frame = 1
Query: 667 DNCNSENIICFNNGTCVS--GAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCI---KSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
DNC EN C G C S G +C C GF+GP CE D C C N G C+ + N + C C Y GK+C+ CN C C
Sbjct: 698 DNC-GENADCSGKGVCYSNSGMEEYECQCCSGFAGPHCEEIDACNPSPCTNNGICVDLSQGHEGNSYQCLCPYGYAGKNCQYESDPCNPAECMNGGSC 794
BLAST of Jagged-like vs. Ensembl Fly
Match: wry (gene:FBgn0051665 transcript:FBtr0304911) HSP 1 Score: 59.3066 bits (142), Expect = 8.387e-9 Identity = 35/98 (35.71%), Postives = 42/98 (42.86%), Query Frame = 1
Query: 667 DNCNSENIICFNNGTCVS--GAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCI---KSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
DNC EN C G C S G +C C GF+GP CE D C C N G C+ + N + C C Y GK+C+ CN C C
Sbjct: 698 DNC-GENADCSGKGVCYSNSGMEEYECQCCSGFAGPHCEEIDACNPSPCTNNGICVDLSQGHEGNSYQCLCPYGYAGKNCQYESDPCNPAECMNGGSC 794
BLAST of Jagged-like vs. Ensembl Fly
Match: wry (gene:FBgn0051665 transcript:FBtr0334823) HSP 1 Score: 59.3066 bits (142), Expect = 8.461e-9 Identity = 35/98 (35.71%), Postives = 42/98 (42.86%), Query Frame = 1
Query: 667 DNCNSENIICFNNGTCVS--GAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCI---KSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
DNC EN C G C S G +C C GF+GP CE D C C N G C+ + N + C C Y GK+C+ CN C C
Sbjct: 699 DNC-GENADCSGKGVCYSNSGMEEYECQCCSGFAGPHCEEIDACNPSPCTNNGICVDLSQGHEGNSYQCLCPYGYAGKNCQYESDPCNPAECMNGGSC 795
BLAST of Jagged-like vs. Ensembl Zebrafish
Match: notch1a (notch receptor 1a [Source:NCBI gene;Acc:30718]) HSP 1 Score: 67.3958 bits (163), Expect = 3.516e-11 Identity = 46/159 (28.93%), Postives = 71/159 (44.65%), Query Frame = 1
Query: 526 CKPGFFP---KNRCLVS--CFEEASVYKCDENGRKICLSGYVFDPL---TNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKC-IKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
C P P + RC C + Y C +C +G+V + N+C D C+ + CV ++ +C C G++G CE +++ C CKNGG C + S K+ +IC C+ Y G SCE +SC + C C + P+C
Sbjct: 441 CSPSVDPLTGEPRCFNGGRCVDRVGGYGC------VCPAGFVGERCEGDVNECLSDPCDPSG-----SYNCVQLINDFRCECRTGYTGKRCETVFNGCKDTPCKNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQSCGSLRCRNGATCVSGHLSPRC 588 HSP 2 Score: 62.003 bits (149), Expect = 2.090e-9 Identity = 34/105 (32.38%), Postives = 49/105 (46.67%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
N++ C S C N G+C+ KC C+ ++G CE + PC+ CKNGG C +SE F C C + G++CE C C CE + +C
Sbjct: 7 NINECASNP--CLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQC 109 HSP 3 Score: 59.6918 bits (143), Expect = 1.099e-8 Identity = 37/121 (30.58%), Postives = 55/121 (45.45%), Query Frame = 1
Query: 616 ICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDP-CTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCS 975
+CL+G+ + ++D C S C N G C ++ C C GFSG +CEI P CT+ C NGG C+ + F C C + G C+ C+ C+ C+ KC+
Sbjct: 148 VCLAGFRGERCAE--DIDECVSAP--CRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDG--ISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCT 262 HSP 4 Score: 57.3806 bits (137), Expect = 5.342e-8 Identity = 29/97 (29.90%), Postives = 46/97 (47.42%), Query Frame = 1
Query: 658 CNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C ++ + CFN GTCV G + C C+ GF+G C+ + C C+NGG C + + C C + Y G +C+ + C+ C+ C
Sbjct: 196 CEINTPDCTESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSC--QDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSC 290 HSP 5 Score: 55.4546 bits (132), Expect = 1.722e-7 Identity = 29/82 (35.37%), Postives = 40/82 (48.78%), Query Frame = 1
Query: 652 NKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE--IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSC 891
+ C D+ + ++ C N TCVSG +P+C C GFSG C+ + PC C NGG C + C C N+ G C
Sbjct: 559 SSCEYDSQSCGSLRCRNGATCVSGHLSPRCLCAPGFSGHECQTRMDSPCLVNPCYNGGTCQPISDAPFYRCSCPANFNGLLC 640 HSP 6 Score: 53.5286 bits (127), Expect = 7.418e-7 Identity = 30/96 (31.25%), Postives = 43/96 (44.79%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
++D+C E C N G C + C C+ GF G C E D C C+NGG C ++ N + C C + G +CE C + +C C
Sbjct: 123 DIDDC--EPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNC--TDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTC 214 HSP 7 Score: 52.7582 bits (125), Expect = 1.507e-6 Identity = 38/150 (25.33%), Postives = 63/150 (42.00%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYV---FDPLTNKCNL---DNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSK 993
SC+++ + + C C SG+ D + C + S ++C + G CV + C C G++G C E D C C+NG C ++ + C C Y+G +C K C C+ C + N KCS + ++
Sbjct: 289 SCWQQGASFTCQ------CASGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGATC--TDYLGGYSCECVPGYHGMNCSKEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQ 430
BLAST of Jagged-like vs. Ensembl Zebrafish
Match: jag2b (jagged canonical Notch ligand 2b [Source:ZFIN;Acc:ZDB-GENE-011128-3]) HSP 1 Score: 65.0846 bits (157), Expect = 2.203e-10 Identity = 35/85 (41.18%), Postives = 47/85 (55.29%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C N GTC+ G + +CFC DG+ G C I + C++ CKNGG C+ +L NDF C C N + GK+C C+ TC C
Sbjct: 608 CRNGGTCIDGISSFQCFCPDGWEGDLCSINVNECSRSPCKNGGHCV--DLVNDFYCECANGWKGKTCHSRESQCDSSTCSNGGTC 690
BLAST of Jagged-like vs. Ensembl Zebrafish
Match: jag2b (jagged canonical Notch ligand 2b [Source:ZFIN;Acc:ZDB-GENE-011128-3]) HSP 1 Score: 64.6994 bits (156), Expect = 2.241e-10 Identity = 35/85 (41.18%), Postives = 47/85 (55.29%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C N GTC+ G + +CFC DG+ G C I + C++ CKNGG C+ +L NDF C C N + GK+C C+ TC C
Sbjct: 608 CRNGGTCIDGISSFQCFCPDGWEGDLCSINVNECSRSPCKNGGHCV--DLVNDFYCECANGWKGKTCHSRESQCDSSTCSNGGTC 690
BLAST of Jagged-like vs. Ensembl Zebrafish
Match: jag2b (jagged canonical Notch ligand 2b [Source:ZFIN;Acc:ZDB-GENE-011128-3]) HSP 1 Score: 64.6994 bits (156), Expect = 2.547e-10 Identity = 35/85 (41.18%), Postives = 47/85 (55.29%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C N GTC+ G + +CFC DG+ G C I + C++ CKNGG C+ +L NDF C C N + GK+C C+ TC C
Sbjct: 646 CRNGGTCIDGISSFQCFCPDGWEGDLCSINVNECSRSPCKNGGHCV--DLVNDFYCECANGWKGKTCHSRESQCDSSTCSNGGTC 728
BLAST of Jagged-like vs. Ensembl Zebrafish
Match: jag2b (jagged canonical Notch ligand 2b [Source:ZFIN;Acc:ZDB-GENE-011128-3]) HSP 1 Score: 64.6994 bits (156), Expect = 2.569e-10 Identity = 35/85 (41.18%), Postives = 47/85 (55.29%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C N GTC+ G + +CFC DG+ G C I + C++ CKNGG C+ +L NDF C C N + GK+C C+ TC C
Sbjct: 646 CRNGGTCIDGISSFQCFCPDGWEGDLCSINVNECSRSPCKNGGHCV--DLVNDFYCECANGWKGKTCHSRESQCDSSTCSNGGTC 728
BLAST of Jagged-like vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 66.6254 bits (161), Expect = 9.767e-11 Identity = 48/142 (33.80%), Postives = 71/142 (50.00%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTC--VSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVK 981
+C + + YKCD C +G+ + C+++N E+ C N GTC ++GA+ C C GFSG CE + PC+ CKNGG+C +SE F C C + G++CE C + C C+ N KC+ K
Sbjct: 619 TCHDGINGYKCD------CDAGWS----GSNCDVNNNECESNPCMNGGTCKDMTGAY--ICTCRAGFSGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK 748
BLAST of Jagged-like vs. Ensembl Xenopus
Match: plpp7 (phospholipid phosphatase 7 (inactive) [Source:Xenbase;Acc:XB-GENE-977766]) HSP 1 Score: 65.855 bits (159), Expect = 1.769e-10 Identity = 39/96 (40.62%), Postives = 53/96 (55.21%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C S C N GTC+ G ++ KC C DG+ G CE + C+K C NGG C +L NDF C CKN + GK+C C++ TC C
Sbjct: 594 NINDCESN--PCKNGGTCIDGVNSYKCICSDGWEGIYCETNINDCSKNPCYNGGTC--RDLVNDFYCECKNGWKGKTCHSRDSQCDEATCNNGGTC 685
BLAST of Jagged-like vs. Ensembl Xenopus
Match: plpp7 (phospholipid phosphatase 7 (inactive) [Source:Xenbase;Acc:XB-GENE-977766]) HSP 1 Score: 65.4698 bits (158), Expect = 2.030e-10 Identity = 39/96 (40.62%), Postives = 53/96 (55.21%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C S C N GTC+ G ++ KC C DG+ G CE + C+K C NGG C +L NDF C CKN + GK+C C++ TC C
Sbjct: 632 NINDCESN--PCKNGGTCIDGVNSYKCICSDGWEGIYCETNINDCSKNPCYNGGTC--RDLVNDFYCECKNGWKGKTCHSRDSQCDEATCNNGGTC 723
BLAST of Jagged-like vs. Ensembl Xenopus
Match: plpp7 (phospholipid phosphatase 7 (inactive) [Source:Xenbase;Acc:XB-GENE-977766]) HSP 1 Score: 65.0846 bits (157), Expect = 2.881e-10 Identity = 39/96 (40.62%), Postives = 53/96 (55.21%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C S C N GTC+ G ++ KC C DG+ G CE + C+K C NGG C +L NDF C CKN + GK+C C++ TC C
Sbjct: 629 NINDCESN--PCKNGGTCIDGVNSYKCICSDGWEGIYCETNINDCSKNPCYNGGTC--RDLVNDFYCECKNGWKGKTCHSRDSQCDEATCNNGGTC 720
BLAST of Jagged-like vs. Ensembl Xenopus
Match: plpp7 (phospholipid phosphatase 7 (inactive) [Source:Xenbase;Acc:XB-GENE-977766]) HSP 1 Score: 65.0846 bits (157), Expect = 3.034e-10 Identity = 39/96 (40.62%), Postives = 53/96 (55.21%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C S C N GTC+ G ++ KC C DG+ G CE + C+K C NGG C +L NDF C CKN + GK+C C++ TC C
Sbjct: 629 NINDCESN--PCKNGGTCIDGVNSYKCICSDGWEGIYCETNINDCSKNPCYNGGTC--RDLVNDFYCECKNGWKGKTCHSRDSQCDEATCNNGGTC 720
BLAST of Jagged-like vs. Ensembl Mouse
Match: Sned1 (sushi, nidogen and EGF-like domains 1 [Source:MGI Symbol;Acc:MGI:3045960]) HSP 1 Score: 64.6994 bits (156), Expect = 2.996e-10 Identity = 42/139 (30.22%), Postives = 62/139 (44.60%), Query Frame = 1
Query: 550 NRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC-EIVNN 960
+C+ C Y C CL+G+ +C+LD + C N GTC G ++ C C GF GP+CE PC C+NGG+C + +C C+ Y G +CE C+ C+ C ++V N
Sbjct: 282 GKCIDDCVTGNPSYTCS------CLAGFT----GRRCHLDVNECASHPCQNGGTCTHGVNSFSCQCPAGFKGPTCESAQSPCDNKVCQNGGQCQAE--SSSAVCVCQAGYTGATCETDVDECSSDPCQNGGSCVDLVGN 408 HSP 2 Score: 57.7658 bits (138), Expect = 3.473e-8 Identity = 37/119 (31.09%), Postives = 56/119 (47.06%), Query Frame = 1
Query: 616 ICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-----IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVN 957
+C +GY T + ++D C+S+ C N G+CV N C CV+ F GP CE + PC C+NGG C+ ++ ++C C + G C + + ND C C N
Sbjct: 374 VCQAGYTG--ATCETDVDECSSDP--CQNGGSCVDLVGNYSCICVEPFEGPQCETGSYLVPSPCLSNPCQNGGTCVDAD--EGYVCECPEGFMGLDCRE--RILNDCDCRNGGRCLGAN 484 HSP 3 Score: 53.5286 bits (127), Expect = 8.216e-7 Identity = 33/77 (42.86%), Postives = 39/77 (50.65%), Query Frame = 1
Query: 667 DNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIW-DPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCE 894
D+C S C N GTC KC C GFSG CEI PC + C NGG C +L DF C+C+ Y G C+
Sbjct: 621 DSCASGP--CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCMNGGTC--EDLGTDFSCYCQPGYTGHRCQ 693 HSP 4 Score: 53.1434 bits (126), Expect = 1.017e-6 Identity = 33/113 (29.20%), Postives = 49/113 (43.36%), Query Frame = 1
Query: 613 KICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCE 948
++C V+ +D C S+ C + G+C + +C C G+ G CE+ D C C+NGG C +L FIC C + G CE +C C+ CE
Sbjct: 737 RVCQPQGVWSQPPQCIEVDECRSQP--CLHGGSCQDLIADYQCLCSPGYEGVHCELETDECQAQPCRNGGSC--RDLPRAFICQCPEGFVGIHCETEVDACASSPCQHGGRCE 845
BLAST of Jagged-like vs. Ensembl Mouse
Match: Vcan (versican [Source:MGI Symbol;Acc:MGI:102889]) HSP 1 Score: 62.7734 bits (151), Expect = 1.255e-9 Identity = 32/96 (33.33%), Postives = 46/96 (47.92%), Query Frame = 1
Query: 631 YVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCN 915
Y+ + NK D C + C N GTC + C C G+SG CE+ +D C C+NG C+ N F C C +Y G CE+ ++C+
Sbjct: 1298 YIIEVRENKTGPDLCKTNP--CLNGGTCYPTETSYVCTCAPGYSGDQCELDFDECHSNPCRNGATCVDG--FNTFRCLCLPSYVGALCEQDTETCD 1389
BLAST of Jagged-like vs. Ensembl Mouse
Match: Jag1 (jagged 1 [Source:MGI Symbol;Acc:MGI:1095416]) HSP 1 Score: 62.003 bits (149), Expect = 1.653e-9 Identity = 39/97 (40.21%), Postives = 54/97 (55.67%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE--IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C E+ C N GTC+ G ++ KC C DG+ G CE I D C++ C GG C +L NDF C CKN + GK+C C++ TC C
Sbjct: 629 NINDC--ESNPCKNGGTCIDGVNSYKCICSDGWEGAHCENNIND-CSQNPCHYGGTC--RDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTC 720 HSP 2 Score: 57.3806 bits (137), Expect = 5.544e-8 Identity = 48/166 (28.92%), Postives = 69/166 (41.57%), Query Frame = 1
Query: 478 IHSQDFATLSVDIVIKCKPGFFPKN------RCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIV 954
++++ L C PG+ +N CL C +AS R IC GY D ++D C S C N G C + + +C C GFSG C++ D C C+NG +C +D+ C C +Y GK+C C TCE C +
Sbjct: 422 VNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCER--DIDECASN--PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNR--ASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDSCTVA 581
BLAST of Jagged-like vs. Ensembl Mouse
Match: Vcan (versican [Source:MGI Symbol;Acc:MGI:102889]) HSP 1 Score: 59.6918 bits (143), Expect = 1.109e-8 Identity = 27/75 (36.00%), Postives = 38/75 (50.67%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCN 915
C N GTC + C C G+SG CE+ +D C C+NG C+ N F C C +Y G CE+ ++C+
Sbjct: 3056 CLNGGTCYPTETSYVCTCAPGYSGDQCELDFDECHSNPCRNGATCVDG--FNTFRCLCLPSYVGALCEQDTETCD 3128
BLAST of Jagged-like vs. Ensembl Mouse
Match: Vcan (versican [Source:MGI Symbol;Acc:MGI:102889]) HSP 1 Score: 59.3066 bits (142), Expect = 1.321e-8 Identity = 27/75 (36.00%), Postives = 38/75 (50.67%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCN 915
C N GTC + C C G+SG CE+ +D C C+NG C+ N F C C +Y G CE+ ++C+
Sbjct: 2096 CLNGGTCYPTETSYVCTCAPGYSGDQCELDFDECHSNPCRNGATCVDG--FNTFRCLCLPSYVGALCEQDTETCD 2168
BLAST of Jagged-like vs. UniProt/SwissProt
Match: sp|P78504|JAG1_HUMAN (Protein jagged-1 OS=Homo sapiens OX=9606 GN=JAG1 PE=1 SV=3) HSP 1 Score: 65.855 bits (159), Expect = 9.441e-10 Identity = 38/96 (39.58%), Postives = 54/96 (56.25%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C E+ C N GTC+ G ++ KC C DG+ G CE + C++ C NGG C +L NDF C CKN + GK+C C++ TC C
Sbjct: 629 NINDC--ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC--RDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTC 720 HSP 2 Score: 54.6842 bits (130), Expect = 2.223e-6 Identity = 47/166 (28.31%), Postives = 68/166 (40.96%), Query Frame = 1
Query: 478 IHSQDFATLSVDIVIKCKPGFFPKN------RCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIV 954
++++ L C PG+ +N CL C +AS R IC GY D ++D C S C N G C + + +C C GFSG C++ D C C+NG +C +D+ C C +Y GK+C C CE C +
Sbjct: 422 VNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCER--DIDECASN--PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNR--ASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVA 581
BLAST of Jagged-like vs. UniProt/SwissProt
Match: sp|Q70E20|SNED1_MOUSE (Sushi, nidogen and EGF-like domain-containing protein 1 OS=Mus musculus OX=10090 GN=Sned1 PE=2 SV=2) HSP 1 Score: 64.6994 bits (156), Expect = 2.060e-9 Identity = 42/139 (30.22%), Postives = 62/139 (44.60%), Query Frame = 1
Query: 550 NRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC-EIVNN 960
+C+ C Y C CL+G+ +C+LD + C N GTC G ++ C C GF GP+CE PC C+NGG+C + +C C+ Y G +CE C+ C+ C ++V N
Sbjct: 282 GKCIDDCVTGNPSYTCS------CLAGFT----GRRCHLDVNECASHPCQNGGTCTHGVNSFSCQCPAGFKGPTCESAQSPCDNKVCQNGGQCQAE--SSSAVCVCQAGYTGATCETDVDECSSDPCQNGGSCVDLVGN 408 HSP 2 Score: 58.151 bits (139), Expect = 2.388e-7 Identity = 37/119 (31.09%), Postives = 56/119 (47.06%), Query Frame = 1
Query: 616 ICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-----IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVN 957
+C +GY T + ++D C+S+ C N G+CV N C CV+ F GP CE + PC C+NGG C+ ++ ++C C + G C + + ND C C N
Sbjct: 374 VCQAGYTG--ATCETDVDECSSDP--CQNGGSCVDLVGNYSCICVEPFEGPQCETGSYLVPSPCLSNPCQNGGTCVDAD--EGYVCECPEGFMGLDCRE--RILNDCDCRNGGRCLGAN 484 HSP 3 Score: 53.5286 bits (127), Expect = 5.747e-6 Identity = 33/77 (42.86%), Postives = 39/77 (50.65%), Query Frame = 1
Query: 667 DNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIW-DPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCE 894
D+C S C N GTC KC C GFSG CEI PC + C NGG C +L DF C+C+ Y G C+
Sbjct: 621 DSCASGP--CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCMNGGTC--EDLGTDFSCYCQPGYTGHRCQ 693 HSP 4 Score: 53.1434 bits (126), Expect = 7.115e-6 Identity = 33/113 (29.20%), Postives = 49/113 (43.36%), Query Frame = 1
Query: 613 KICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCE 948
++C V+ +D C S+ C + G+C + +C C G+ G CE+ D C C+NGG C +L FIC C + G CE +C C+ CE
Sbjct: 737 RVCQPQGVWSQPPQCIEVDECRSQP--CLHGGSCQDLIADYQCLCSPGYEGVHCELETDECQAQPCRNGGSC--RDLPRAFICQCPEGFVGIHCETEVDACASSPCQHGGRCE 845
BLAST of Jagged-like vs. UniProt/SwissProt
Match: sp|P46531|NOTC1_HUMAN (Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4) HSP 1 Score: 64.3142 bits (155), Expect = 2.529e-9 Identity = 38/123 (30.89%), Postives = 56/123 (45.53%), Query Frame = 1
Query: 625 SGYV------FDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
SGYV F + N++ C S C N GTC+ KC C+ ++G +CE+ PC C+NGG+C +SE F C C + G++CE C C C+ + +C
Sbjct: 773 SGYVCTCREGFSGPNCQTNINECASNP--CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRC 893 HSP 2 Score: 59.3066 bits (142), Expect = 9.463e-8 Identity = 37/122 (30.33%), Postives = 55/122 (45.08%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITC 927
+C ++ ++C IC+ GY + + + N D C S C +NG C+ + +C C GF+G C+ D C CKNG KC+ N + C C Y G CE C+ C
Sbjct: 466 TCLDQIGEFQC------ICMPGY--EGVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDG--PNTYTCVCTEGYTGTHCEVDIDECDPDPC 575 HSP 3 Score: 57.3806 bits (137), Expect = 4.038e-7 Identity = 43/152 (28.29%), Postives = 61/152 (40.13%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCN------SENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSF 999
+C + + YKC C G + + N+D+CN S + CFNNGTCV C C GF G CE + C C G + NDF C C+ + G+ CE C C+ C + +N + + K F
Sbjct: 1197 TCLDLPNTYKCS------CPRGT--QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340 HSP 4 Score: 55.4546 bits (132), Expect = 1.581e-6 Identity = 32/91 (35.16%), Postives = 44/91 (48.35%), Query Frame = 1
Query: 643 PLTNKCNLDNCNSENIICFNNGTC-VSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSC 912
PL N C + C N GTC + KC C G+SG SC+ DPC C NGG+C+ E +IC C +++G +C + C
Sbjct: 101 PLDNACLTNPCR-------NGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEAS--YICHCPPSFHGPTCRQDVNEC 182 HSP 5 Score: 54.6842 bits (130), Expect = 2.896e-6 Identity = 43/157 (27.39%), Postives = 65/157 (41.40%), Query Frame = 1
Query: 526 CKPGFFPK------NRCLVS-CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
C PGF N C C A+ C ++ C +G F + + N +C + CFN GTCV G ++ C C GF+G C+ + C C +GG C + + C C Y G +C+ C+ C+ C + Q +C
Sbjct: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAG--FSGIHCENNTPDCTESS--CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTC--QDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRC 1083 HSP 6 Score: 54.299 bits (129), Expect = 3.645e-6 Identity = 37/126 (29.37%), Postives = 57/126 (45.24%), Query Frame = 1
Query: 604 NGRKICL--SGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
NG+ IC SGY + ++D C+ C + G C++ + +C C+ G++GP CEI + C C+N C+ + +F C C Y G CE C C N C N+ +C
Sbjct: 393 NGKAICTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL--DQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQC 514 HSP 7 Score: 53.1434 bits (126), Expect = 7.850e-6 Identity = 37/134 (27.61%), Postives = 56/134 (41.79%), Query Frame = 1
Query: 550 NRCLVS-CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N C++S C AS R C +GY + ++D+C C N G+C G + C C+ GF G C E + C C+NG C ++ + + C C + G CE C + +C C
Sbjct: 871 NECVLSPCRHGASCQNTHGGYRCHCQAGY--SGRNCETDIDDCRPNP--CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC--TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC 998
BLAST of Jagged-like vs. UniProt/SwissProt
Match: sp|A0A1F4|EYS_DROME (Protein eyes shut OS=Drosophila melanogaster OX=7227 GN=eys PE=1 SV=1) HSP 1 Score: 64.3142 bits (155), Expect = 2.969e-9 Identity = 44/129 (34.11%), Postives = 55/129 (42.64%), Query Frame = 1
Query: 565 SCFEEASVYKCDENGRKICLSGYVFDPLTN---KCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSC-EIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQ 939
+C V+ +G S Y D T + N D C S C N GTCV G C C +GFSG +C E D C C+NGG C + N +IC C+ Y G CE C T + Q
Sbjct: 147 ACLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSP--CQNGGTCVDGVAYYNCTCPEGFSGSNCEENVDECMSNPCQNGGLC--RDRTNGYICTCQPGYLGSHCELDVAVCETGTGARCQ 271 HSP 2 Score: 60.077 bits (144), Expect = 6.553e-8 Identity = 29/102 (28.43%), Postives = 47/102 (46.08%), Query Frame = 1
Query: 694 CFNN----GTCVSGAHNP-KCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVK 981
C +N G C+ G ++ C+C+DG++G C+ WD C C+NGG C+ + C C + G +CE+ C C+ C N C+ +
Sbjct: 148 CLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSPCQNGGTCVDGVAY--YNCTCPEGFSGSNCEENVDECMSNPCQNGGLCRDRTNGYICTCQ 247
BLAST of Jagged-like vs. UniProt/SwissProt
Match: sp|Q8TER0|SNED1_HUMAN (Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNED1 PE=2 SV=2) HSP 1 Score: 63.1586 bits (152), Expect = 6.023e-9 Identity = 43/140 (30.71%), Postives = 65/140 (46.43%), Query Frame = 1
Query: 550 NRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPRCKNGGKCIKSELKND-FICFCKNNYYGKSCEKTGKSCNDITCEKNQFC-EIVNN 960
+C+ C Y C CLSG+ +C+LD + C N GTC G ++ +C C GF GP+CE PC C++GG+C +++N +C C+ Y G +CE C+ C C ++V N
Sbjct: 282 GKCIDDCVTGNPSYTCS------CLSGFT----GRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQC---QVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGN 408 HSP 2 Score: 52.7582 bits (125), Expect = 8.896e-6 Identity = 33/124 (26.61%), Postives = 54/124 (43.55%), Query Frame = 1
Query: 601 ENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-----IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVN 957
ENG +C+ + + ++D+C+ + C N G+CV N C C + F G CE + D C C NGG C+ ++ ++C C + G C + + +D C C N
Sbjct: 367 ENGSAVCVCQAGYTGAACEMDVDDCSPDP--CLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD--QGYVCECPEGFMGLDCRE--RVPDDCECRNGGRCLGAN 484
BLAST of Jagged-like vs. TrEMBL
Match: A0A1Z1R174 (Jagged-like (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1077 bits (2784), Expect = 0.000e+0 Identity = 525/529 (99.24%), Postives = 528/529 (99.81%), Query Frame = 1
Query: 94 FLRTFILLSINFLNNISAIKRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNYFHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILVKTENFKNIIIQNLYGATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKFVSLNVETKKPIVESIPVSKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSSEENFRRWHSLDDNSFYLCNQGHVEPYHTYRSGSNVYPKHEQGIETCRDGYGSLNSSHRMCHSIMRTRMPVLCEPSTVNSSDLNFKYTNDSQNNSEKVDDYNNNYLVIDNPPTSDL 1680
FLRTFILLSINFLNNISAIKRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNYFHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILVKTENFKNIIIQNLYGA+QIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGK+CEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKFVSLNVETKKPIVESIPV+KGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSSEENFRRWHSLDDNSFYLCNQGHVEPYHTYRSGSNVYPKHEQGIETCRDGYGSLNSSHRMCHSIMRTRMPVLCEPSTVNS DLNFKYTNDSQNNSEKVDDYNNNYLVIDNPPTSDL
Sbjct: 1 FLRTFILLSINFLNNISAIKRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNYFHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILVKTENFKNIIIQNLYGASQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKNCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKFVSLNVETKKPIVESIPVNKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSSEENFRRWHSLDDNSFYLCNQGHVEPYHTYRSGSNVYPKHEQGIETCRDGYGSLNSSHRMCHSIMRTRMPVLCEPSTVNSGDLNFKYTNDSQNNSEKVDDYNNNYLVIDNPPTSDL 529
BLAST of Jagged-like vs. TrEMBL
Match: A0A3M7TAC8 (Neurogenic locus notch 2-like protein OS=Brachionus plicatilis OX=10195 GN=BpHYR1_024136 PE=4 SV=1) HSP 1 Score: 75.485 bits (184), Expect = 1.057e-10 Identity = 47/119 (39.50%), Postives = 63/119 (52.94%), Query Frame = 1
Query: 625 SGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPK--CFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
S ++ L NK NLD C E C N+G CV C C+ F+G +CEI +PC+ +C N G C+ + + F C C YGK CEK C++ TC KN CE N++PKC
Sbjct: 238 SDHLIHVLENKYNLDGCLKE---CSNHGDCVYDKFKDSYICQCLPSFAGQACEINLEPCSSLQCLNNGTCVSFKNRT-FFCICSPISYGKRCEKLVDVCHNQTCSKNGICEPFNHKPKC 352
BLAST of Jagged-like vs. TrEMBL
Match: A0A2T7PQL3 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_02684 PE=4 SV=1) HSP 1 Score: 74.3294 bits (181), Expect = 2.500e-10 Identity = 67/247 (27.13%), Postives = 109/247 (44.13%), Query Frame = 1
Query: 466 GATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCD-ENGRKICLSGYVFDPLTNKCN---------LDNCNSENIICFNNGTCVSGAHNP-KCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPK----CSVKKNSKSFIQKTFVTPPSIKSTTITKPKF-VSLNVETKKPIVESIPVSKGTNRLLQSHSLLN 1158
G TQ+ A+L + + I C +F N CL C S Y+CD GR++CL G +P + N L++C S N C N G C A + C C G+SG CE + C+ C NGGKC ++ D+ C C + G +C+ C+ C+ C ++ + + +++S+ + ++ S T+ P VS + P V+ + ++ LLQ LL+
Sbjct: 161 GITQLRGIPSASLRIQVKIYCATNYF-GNLCLTFCRPVPSRYRCDVSTGRRVCL-GLWLEPDCEEGNDAGPYLCAALNDCRSMNYGCLNGGLCQGTASSAFACRCPTGYSGARCEN-NVCSPSPCYNGGKC-RAVNATDWTCDCLPGFTGSTCD-VASPCDSSPCQNGGRCYQTSSGGEYRWTPTRGTDARSWHPVLRLLAVTVVSVTLGVPPLSVSAQLAGAAPRVKPVTFAR-PQSLLQWRCLLS 401
BLAST of Jagged-like vs. TrEMBL
Match: A0A2E6VMX4 (Uncharacterized protein OS=Myxococcales bacterium OX=2026763 GN=CMH56_00945 PE=4 SV=1) HSP 1 Score: 74.7146 bits (182), Expect = 4.572e-10 Identity = 49/159 (30.82%), Postives = 69/159 (43.40%), Query Frame = 1
Query: 517 VIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKI--------------CLSGYVFDPLTNKC-NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
V +C+PGF E + +CDEN C GYV + C N+++C S C N GTC G C C++G+SG +CE D CT C+NGG C+ ND+ C C + G++CE C C+ + C
Sbjct: 155 VCECRPGFSGD-----GVDECTDINECDENNGNCSHTCTNTSGGFVCSCDDGYVLNDDGFNCDNINDCASNP--CENGGTCNDGIGGYTCQCLEGYSGDNCETNIDDCTGAPCQNGGTCVDG--VNDYSCTCATGFEGENCETNSDDCTPNPCQNDGTC 304 HSP 2 Score: 61.2326 bits (147), Expect = 7.929e-6 Identity = 34/99 (34.34%), Postives = 46/99 (46.46%), Query Frame = 1
Query: 619 CLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSC 912
CL GY D + N+D+C C N GTCV G ++ C C GF G +CE D CT C+N G C+ + + C C + G C + C
Sbjct: 239 CLEGYSGD--NCETNIDDCTGAP--CQNGGTCVDGVNDYSCTCATGFEGENCETNSDDCTPNPCQNDGTCVDG--VDAYTCNCTTGFKGADCSEDIDEC 331
BLAST of Jagged-like vs. TrEMBL
Match: A0A2E4F7E3 (Uncharacterized protein OS=Deltaproteobacteria bacterium OX=2026735 GN=CL940_00115 PE=4 SV=1) HSP 1 Score: 74.7146 bits (182), Expect = 5.566e-10 Identity = 50/160 (31.25%), Postives = 72/160 (45.00%), Query Frame = 1
Query: 511 DIVIKCKPGFFPKN--RCLVSCFEEASVY--KC-DENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
D + C PGF K + C +E + +C D +C+ F T + ++D+C + C N G C ++ +C C++GF G +CEI D C C NGG C ++ NDF+C C + GKSCE C D C C N C
Sbjct: 129 DFICACPPGFAGKTCETHMDECADEPCLNGGECKDAVNDFVCVCPPGFAGKTCELDIDDCADKP--CLNGGVCTDAVNDFECACLEGFEGETCEINIDDCADAPCLNGGVC--ADAANDFVCVCPAGFSGKSCEINVDDCADAPCLNGGVCTDAANDFVC 284 HSP 2 Score: 68.1662 bits (165), Expect = 5.956e-8 Identity = 35/90 (38.89%), Postives = 47/90 (52.22%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITC 927
N+D+C ++ C N G C G + C CV GF G +CEI D CT C NGG C ++ +DF C C + GK+CE C+ C
Sbjct: 1071 NIDDC--ADVPCLNGGACTDGLNAFTCECVTGFEGATCEINIDDCTPDPCVNGGSC--TDAVDDFACVCPEGFGGKTCEINADDCSPDPC 1156 HSP 3 Score: 66.6254 bits (161), Expect = 1.766e-7 Identity = 35/107 (32.71%), Postives = 48/107 (44.86%), Query Frame = 1
Query: 658 CNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCS 975
C D + + C N G C ++ C C GF+G +CE D C C NGG+C + NDF+C C + GK+CE C D C C N +C+
Sbjct: 105 CETDTDDCASAPCLNGGACTDAVNDFICACPPGFAGKTCETHMDECADEPCLNGGEC--KDAVNDFVCVCPPGFAGKTCELDIDDCADKPCLNGGVCTDAVNDFECA 209 HSP 4 Score: 64.3142 bits (155), Expect = 9.209e-7 Identity = 40/127 (31.50%), Postives = 58/127 (45.67%), Query Frame = 1
Query: 568 CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C ++ + ++C C +G+ D L + N+D+C + CFN C+ G + C C GF G CEI D C C NGG C ++ N F C C++ Y G CE C C+ C
Sbjct: 1161 CIDQVAGFECS------CDAGW--DGLLCQNNIDDCAGQP--CFNGAVCLDGIDSFSCSCWPGFEGSLCEIDIDECAAAPCLNGGVC--TDQVNGFSCSCQDGYEGDLCETDTDGCTPNPCQNGGTC 1275 HSP 5 Score: 61.2326 bits (147), Expect = 7.872e-6 Identity = 42/130 (32.31%), Postives = 60/130 (46.15%), Query Frame = 1
Query: 547 KNRCL--VSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITC 927
+N CL C ++ + CD CL G F+ + N+D+C N C N G+C G C C+ GF G +C I + C C+NGG C ++ N+F C C + GK CE C+ C
Sbjct: 662 ENPCLNGSECLDDVGEFFCD------CLGG--FEGQLCEINIDDC--ANQPCLNGGSCTDGIDEFICECLPGFEGYNCSIDINECIPDPCENGGNC--ADGVNEFACECPPGFGGKLCEINADDCSPDPC 779 HSP 6 Score: 61.2326 bits (147), Expect = 8.007e-6 Identity = 45/158 (28.48%), Postives = 68/158 (43.04%), Query Frame = 1
Query: 511 DIVIKCKPGFFPKNRCLV--SCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCS 975
D V+ P CL SC +E + + C +C +G FD + ++D C + CFN+ C + C C GF+G +C + D C+ C NGG C ++ N F C C + G++C+ C D C CE KC+
Sbjct: 414 DCVVPSDESEGPLTSCLNGGSCVDEVNGFSC------VCPAG--FDGAFCENDIDEC--ADTPCFNDSVCTDEVNGFSCECSPGFAGATCSVNIDDCSPNPCYNGGVC--ADEVNGFTCDCVVGFEGQTCQSNIDDCADEPCLNGGVCEDAFIDFKCT 559
BLAST of Jagged-like vs. Ensembl Cavefish
Match: JAG1 (protein jagged-1a [Source:NCBI gene;Acc:103036342]) HSP 1 Score: 65.4698 bits (158), Expect = 1.175e-10 Identity = 39/105 (37.14%), Postives = 56/105 (53.33%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
N+++C E+ C N GTC+ + +C C DG+ GP+CE D C+ C++ G C +L NDF C CKN + GK+C C++ TC C N KC
Sbjct: 575 NINDC--ESSPCGNGGTCIDKVNVYQCICADGWEGPNCETNIDDCSTNPCRDRGVC--RDLVNDFYCECKNGWKGKTCHSRESQCDEATCNNGGTCSDEGNSFKC 675 HSP 2 Score: 52.7582 bits (125), Expect = 1.017e-6 Identity = 30/85 (35.29%), Postives = 44/85 (51.76%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
CFN G+CV + +C C G++GPSC I D C+ C + G C+ +L N F C C + + GK+C C++ C C
Sbjct: 349 CFNGGSCVESSQGFECRCSPGWTGPSCTINEDDCSPNPCNHAGTCV--DLINGFRCLCPSQWSGKTCLIDANECDENPCVNAHSC 431
BLAST of Jagged-like vs. Ensembl Cavefish
Match: JAG1 (protein jagged-1a [Source:NCBI gene;Acc:103036342]) HSP 1 Score: 65.0846 bits (157), Expect = 1.488e-10 Identity = 39/105 (37.14%), Postives = 56/105 (53.33%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
N+++C E+ C N GTC+ + +C C DG+ GP+CE D C+ C++ G C +L NDF C CKN + GK+C C++ TC C N KC
Sbjct: 633 NINDC--ESSPCGNGGTCIDKVNVYQCICADGWEGPNCETNIDDCSTNPCRDRGVC--RDLVNDFYCECKNGWKGKTCHSRESQCDEATCNNGGTCSDEGNSFKC 733 HSP 2 Score: 53.5286 bits (127), Expect = 5.548e-7 Identity = 52/182 (28.57%), Postives = 78/182 (42.86%), Query Frame = 1
Query: 523 KCKPGFFPKN----------RCL--VSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC--EIVNNQPKCSVKKNSKSFIQKTFVTP 1023
+C PG+ +N +CL SC + + YKC +C G+ + ++D C S C N G C + +C C+ GFSG C++ D C C+NG +C L ND+ C C ++Y GK+C C C+ C +V+N SV+ FI P
Sbjct: 441 ECLPGWTGQNCDINVNDCQGQCLNGGSCKDLVNGYKC------VCAPGFAGEHCER--DIDECASH--PCLNRGRCQDDVNGFQCLCLPGFSGNLCQLDIDYCVGNPCQNGAQCFN--LANDYYCKCPDDYEGKNCSHLKDHCRTTPCQVIDSCTVAVVSNSSAGSVR-----FISSNVCGP 605 HSP 3 Score: 52.7582 bits (125), Expect = 1.208e-6 Identity = 30/85 (35.29%), Postives = 44/85 (51.76%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
CFN G+CV + +C C G++GPSC I D C+ C + G C+ +L N F C C + + GK+C C++ C C
Sbjct: 349 CFNGGSCVESSQGFECRCSPGWTGPSCTINEDDCSPNPCNHAGTCV--DLINGFRCLCPSQWSGKTCLIDANECDENPCVNAHSC 431
BLAST of Jagged-like vs. Ensembl Cavefish
Match: ENSAMXT00000039261.1 (neurocan core protein-like [Source:NCBI gene;Acc:103030700]) HSP 1 Score: 62.3882 bits (150), Expect = 1.137e-9 Identity = 31/75 (41.33%), Postives = 41/75 (54.67%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCN 915
C + GTC+ +CFC G++G SCEI D C C+NGG CI + + FIC C +Y G CEK + C
Sbjct: 912 CLHGGTCLPDGEGFRCFCPQGYTGESCEIDVDDCLSNPCENGGTCI--DKVDSFICLCLPSYSGDMCEKDTEGCE 984
BLAST of Jagged-like vs. Ensembl Cavefish
Match: ENSAMXT00000042001.1 (neurocan core protein-like [Source:NCBI gene;Acc:103030700]) HSP 1 Score: 62.3882 bits (150), Expect = 1.156e-9 Identity = 31/74 (41.89%), Postives = 41/74 (55.41%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSC 912
C + GTC+ +CFC G++G SCEI D C C+NGG CI + + FIC C +Y G CEK + C
Sbjct: 998 CLHGGTCLPDGEGFRCFCPQGYTGESCEIDVDDCLSNPCENGGTCI--DKVDSFICLCLPSYSGDMCEKDTEGC 1069
BLAST of Jagged-like vs. Ensembl Cavefish
Match: jag2b (protein jagged-2 [Source:NCBI gene;Acc:103029720]) HSP 1 Score: 62.3882 bits (150), Expect = 1.161e-9 Identity = 36/96 (37.50%), Postives = 54/96 (56.25%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C S C N GTC+ G ++ +CFC DG+ G C + + C++ CKNGG+C+ + NDF C C N + GK+C C+ TC C
Sbjct: 597 NVNDCVSS--PCRNGGTCIDGINSFQCFCPDGWEGDLCGLNVNECSRNPCKNGGRCV--DQVNDFYCECANGWKGKTCHSRESQCDASTCSNGGTC 688
BLAST of Jagged-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000962.1 (pep scaffold:Pmarinus_7.0:GL477031:38805:53470:-1 gene:ENSPMAG00000000874.1 transcript:ENSPMAT00000000962.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.9214 bits (141), Expect = 2.196e-9 Identity = 32/85 (37.65%), Postives = 48/85 (56.47%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C N GTC+ G + +C C +G+ G CEI + C+ C+N G+C +L NDF C C+N + GK+C + C++ TC C
Sbjct: 399 CKNGGTCIDGVKSYQCICHEGWEGDVCEIDTNDCSPNLCQNRGRC--RDLVNDFYCECRNGWKGKTCHSRERQCDEATCNNGATC 481
BLAST of Jagged-like vs. Ensembl Sea Lamprey
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]) HSP 1 Score: 58.9214 bits (141), Expect = 2.555e-9 Identity = 46/136 (33.82%), Postives = 65/136 (47.79%), Query Frame = 1
Query: 595 CDENGRKICLSGYVFDPLTNK------CNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE-IWDPCTKPR-CKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSV 978
C NGR + +G F + N C+ + + C N GTC+ G ++ +C C DG+ G CE D C+ C NGG C +L NDF C CKN + GK+C C++ TC C V + +CS
Sbjct: 465 CGPNGRCLSQAGGNFTCMCNSGFRGSFCHENVNDCAEGACHNGGTCLDGINSFQCMCPDGWDGEFCENDVDDCSNHNPCLNGGTC--HDLVNDFSCECKNGWKGKTCHSKISHCDEATCNNGGECFDVGDTFRCSC 598
BLAST of Jagged-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.9214 bits (141), Expect = 2.895e-9 Identity = 38/127 (29.92%), Postives = 55/127 (43.31%), Query Frame = 1
Query: 601 ENGRKICLSGYVFDPLTNKC-----------NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
E+ I +S V +P C ++D C S C + G+C + C C+ GFSG +CE D C + C+NGG C ++ F C C + GK C+ T +C C N C
Sbjct: 1500 ESASVILVSHEVLEPAVCTCTAGYAGTWCEADMDECLSTP--CRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQ--GGFACDCSAGFSGKICDVTVDNCASSPCYNNGSC 1622
BLAST of Jagged-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.9214 bits (141), Expect = 2.922e-9 Identity = 38/127 (29.92%), Postives = 55/127 (43.31%), Query Frame = 1
Query: 601 ENGRKICLSGYVFDPLTNKC-----------NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
E+ I +S V +P C ++D C S C + G+C + C C+ GFSG +CE D C + C+NGG C ++ F C C + GK C+ T +C C N C
Sbjct: 1500 ESASVILVSHEVLEPAVCTCTAGYAGTWCEADMDECLSTP--CRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQ--GGFACDCSAGFSGKICDVTVDNCASSPCYNNGSC 1622
BLAST of Jagged-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001302.1 (pep scaffold:Pmarinus_7.0:GL479305:38781:187025:1 gene:ENSPMAG00000001162.1 transcript:ENSPMAT00000001302.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 57.3806 bits (137), Expect = 8.020e-9 Identity = 37/132 (28.03%), Postives = 54/132 (40.91%), Query Frame = 1
Query: 517 VIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSC 912
+ C GF P + SC S + GR +C SG+ +C++ N C +G+C++G C C G++G SCE C P C G C+ C C + + G SCE C
Sbjct: 150 ICHCNQGFLPPHCSRASCPVLCSGHGQYVRGRCLCHSGWK----GAECDIPAWQCTNPACGGHGSCITGV----CVCNSGYTGESCE-EVMCPHPTCSGKGVCVHG------TCICLSGWGGPSCETRKPMC 266 HSP 2 Score: 55.0694 bits (131), Expect = 5.195e-8 Identity = 38/122 (31.15%), Postives = 52/122 (42.62%), Query Frame = 1
Query: 595 CDENGRKICLSGYVF---DPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI--WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
C NG +CL+G L C+ +C ++C +G V G +C C G+ G C+I W CT P C G CI +C C + Y G+SCE+ C TC C
Sbjct: 140 CHGNG--VCLAGICHCNQGFLPPHCSRASCP---VLCSGHGQYVRG----RCLCHSGWKGAECDIPAWQ-CTNPACGGHGSCITG------VCVCNSGYTGESCEEV--MCPHPTCSGKGVC 243
BLAST of Jagged-like vs. Ensembl Nematostella
Match: EDO31542 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXN5]) HSP 1 Score: 59.3066 bits (142), Expect = 6.818e-11 Identity = 42/110 (38.18%), Postives = 53/110 (48.18%), Query Frame = 1
Query: 568 CFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCE 894
C EE YKC+ C G FD + +D C + C N+GTC+ G N C C GF GP+CEI D C C NGG C+ N ++C C Y G +CE
Sbjct: 12 CKEEVGSYKCE------CALG--FDGTNCEQGVDECAAS--PCLNDGTCIDGPGNYSCICSTGFLGPTCEINVDDCASEPCLNGGACVDG--ANSYLCSCTAGYTGINCE 109
BLAST of Jagged-like vs. Ensembl Nematostella
Match: EDO41767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3G3]) HSP 1 Score: 60.8474 bits (146), Expect = 1.590e-9 Identity = 34/95 (35.79%), Postives = 44/95 (46.32%), Query Frame = 1
Query: 694 CFNNGTCVSGAHNP-KCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
C N G+C++G H+ C C G SG +CE+ PC C G C +DF C C N+ GK CE G CN + C CE + C
Sbjct: 3960 CRNGGSCLAGQHDDFICDCPKGVSGKTCEVDSRPCASNPCFFNGNCTNK--GSDFECKCPNDLSGKRCEH-GFHCNRLPCMNGGSCETRDGAAVC 4051 HSP 2 Score: 50.8322 bits (120), Expect = 1.552e-6 Identity = 27/106 (25.47%), Postives = 41/106 (38.68%), Query Frame = 1
Query: 658 CNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCS 975
C +D+ + CF NG C + + +C C + SG CE C + C NGG C + +C C + G C C C + C +C+
Sbjct: 3987 CEVDSRPCASNPCFFNGNCTNKGSDFECKCPNDLSGKRCEHGFHCNRLPCMNGGSCETRD--GAAVCLCPRGFTGLDCSVDVDECQSNPCLNDGACVNTRGSFRCN 4090
BLAST of Jagged-like vs. Ensembl Nematostella
Match: EDO34151 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ46]) HSP 1 Score: 58.5362 bits (140), Expect = 5.251e-9 Identity = 42/127 (33.07%), Postives = 58/127 (45.67%), Query Frame = 1
Query: 598 DENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCS 975
+++G C F+ + N+D C S C NN CV G +C C GFSG C+ D C+ C+NGG CI +E + C C Y GK+CE + C C+ C N +CS
Sbjct: 281 EQSGGAHCSCPLGFEGAFCELNVDECASN--PCQNNAVCVGGVDKFQCICRPGFSGTLCQFNDDDCSAKPCRNGGSCIDNE--RFYTCACPAGYTGKNCETEVQECQSEPCQHGGTCTKRFNGYECS 403
BLAST of Jagged-like vs. Ensembl Nematostella
Match: EDO41508 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S431]) HSP 1 Score: 55.4546 bits (132), Expect = 3.449e-8 Identity = 42/119 (35.29%), Postives = 56/119 (47.06%), Query Frame = 1
Query: 601 ENG-RKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEI 951
ENG +CL GY +C +D + C N G C+ ++ +C C+ GF G +CE D C C NG CI ND+ C C YY K+CE +C D TCE C +
Sbjct: 248 ENGFECVCLPGYT----GKRCGIDIDDCTPSPCINGGRCIDQVNDYECQCLPGFVGDNCETNVDDCADNPCLNGATCIDG--VNDYYCVCAIGYYSKNCEHKTSTCTDCTCENGGTCGV 360
BLAST of Jagged-like vs. Ensembl Nematostella
Match: EDO28379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6M6]) HSP 1 Score: 54.6842 bits (130), Expect = 3.802e-8 Identity = 32/93 (34.41%), Postives = 48/93 (51.61%), Query Frame = 1
Query: 685 NIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQ 963
++ C N G+CV KC C GF G CE D C CKNGG C +S+ ++ F+C CK + G+ CE + C+ C+ C+ + +
Sbjct: 103 SMPCLNGGSCVEIPGAFKCGCPFGFLGTVCEERDACHPNPCKNGGTCTRSDTESGFVCVCKEGFTGEHCEGFNR-CDPNPCKNGATCQQIKDD 194
BLAST of Jagged-like vs. Ensembl Medaka
Match: jag1b (jagged canonical Notch ligand 1 [Source:NCBI gene;Acc:101168394]) HSP 1 Score: 63.1586 bits (152), Expect = 5.837e-10 Identity = 37/96 (38.54%), Postives = 49/96 (51.04%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C S C N GTC+ +C C DG+ G CEI D C+ C NGG C +L DF C CKN + GK+C C++ TC C
Sbjct: 566 NINDCESN--PCHNGGTCIDKVSVYQCICADGWEGEHCEINIDDCSTSPCHNGGTC--RDLVTDFFCECKNGWKGKTCHSRESQCDEATCNNGGTC 657
BLAST of Jagged-like vs. Ensembl Medaka
Match: jag1b (jagged canonical Notch ligand 1 [Source:NCBI gene;Acc:101168394]) HSP 1 Score: 63.1586 bits (152), Expect = 6.957e-10 Identity = 37/96 (38.54%), Postives = 50/96 (52.08%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C E+ C N GTC+ +C C DG+ G CEI D C+ C NGG C +L DF C CKN + GK+C C++ TC C
Sbjct: 624 NINDC--ESNPCHNGGTCIDKVSVYQCICADGWEGEHCEINIDDCSTSPCHNGGTC--RDLVTDFFCECKNGWKGKTCHSRESQCDEATCNNGGTC 715 HSP 2 Score: 49.6766 bits (117), Expect = 8.924e-6 Identity = 41/151 (27.15%), Postives = 65/151 (43.05%), Query Frame = 1
Query: 523 KCKPGFFPKN------RCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIV 954
+C PG+ +N C C + R +C G+ + L + ++D C S C N G C + +C C+ GFSG C++ D C++ C+NG C ND++C C +Y G++C C TC C +
Sbjct: 432 ECLPGWMGQNCDININDCKDQCQNGGTCKDLVNGYRCLCPPGFTGE-LCER-DVDECASS--PCLNGGRCQDEVNGFQCLCLTGFSGNLCQLDIDYCSQNPCQNGAPCFNR--ANDYVCACPEDYEGRNCSHLKDHCRTTTCTVIDSCTVA 576
BLAST of Jagged-like vs. Ensembl Medaka
Match: jag1b (jagged canonical Notch ligand 1 [Source:NCBI gene;Acc:101168394]) HSP 1 Score: 62.7734 bits (151), Expect = 8.262e-10 Identity = 37/96 (38.54%), Postives = 50/96 (52.08%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
N+++C E+ C N GTC+ +C C DG+ G CEI D C+ C NGG C +L DF C CKN + GK+C C++ TC C
Sbjct: 598 NINDC--ESNPCHNGGTCIDKVSVYQCICADGWEGEHCEINIDDCSTSPCHNGGTC--RDLVTDFFCECKNGWKGKTCHSRESQCDEATCNNGGTC 689
BLAST of Jagged-like vs. Ensembl Medaka
Match: ncanb (neurocan [Source:NCBI gene;Acc:101163561]) HSP 1 Score: 62.3882 bits (150), Expect = 1.025e-9 Identity = 38/113 (33.63%), Postives = 57/113 (50.44%), Query Frame = 1
Query: 577 EASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSC 912
EA K N I + + F + + ++N +N C + G+C+ + C+C GFSG +CEI D C C+NGG CI + N F+C C +Y G +CEK + C
Sbjct: 984 EAEANKDPNNPFGILVPSWAFSLIPS---VENNPCQNNPCLHGGSCLQEGDSYSCYCPQGFSGENCEIDIDDCQSNPCQNGGTCI--DEINSFVCLCLPSYSGATCEKDTEGC 1091
BLAST of Jagged-like vs. Ensembl Medaka
Match: ENSORLT00000040656.1 (protein jagged-1a [Source:NCBI gene;Acc:101169088]) HSP 1 Score: 62.003 bits (149), Expect = 1.294e-9 Identity = 37/105 (35.24%), Postives = 53/105 (50.48%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKC 972
N+++C E C N GTC+ +C C G+ GP+CE D C+ C+N G C +L NDF C C + + GK+C C+D+TC C + KC
Sbjct: 630 NINDC--EIAPCLNGGTCIDEVSRYRCICPKGWEGPTCENNIDDCSSAPCQNRGVC--QDLTNDFYCKCGDGWKGKTCSSRESQCDDVTCNNGGTCYDEGDAFKC 730 HSP 2 Score: 52.373 bits (124), Expect = 1.550e-6 Identity = 34/99 (34.34%), Postives = 50/99 (50.51%), Query Frame = 1
Query: 661 NLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIV 954
+LD+C S C N G+C ++ C C GFSG C++ D C C NGG+C S +D+IC C +Y GK+C + C +C+ C +
Sbjct: 488 DLDDCASG--PCLNGGSCHDRVNDFHCLCPPGFSGRRCQLDIDFCLDSPCLNGGQCFNS--VDDYICECPEDYEGKNCSRLRDHCLTASCKVIDSCTVA 582
BLAST of Jagged-like vs. Planmine SMEST
Match: SMESG000005484.1 (SMESG000005484.1) HSP 1 Score: 1091.26 bits (2821), Expect = 0.000e+0 Identity = 532/535 (99.44%), Postives = 533/535 (99.63%), Query Frame = 1
Query: 76 MNLFNNFLRTFILLSINFLNNISAIKRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNYFHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILVKTENFKNIIIQNLYGATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKFVSLNVETKKPIVESIPVSKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSSEENFRRWHSLDDNSFYLCNQGHVEPYHTYRSGSNVYPKHEQGIETCRDGYGSLNSSHRMCHSIMRTRMPVLCEPSTVNSSDLNFKYTNDSQNNSEKVDDYNNNYLVIDNPPTSDL 1680
MNLFNNFLRTFILLSINFLNNISAIKRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNYFHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILVKTENFKNIIIQNLYGATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPC KPRCKNGGKCIKSELKNDFICFCKNNYYGK+CEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPK VSLNVETKKPIVESIPVSKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSSEENFRRWHSLDDNSFYLCNQGHVEPYHTYRSGSNVYPKHEQGIETCRDGYGSLNSSHRMCHSIMRTRMPVLCEPSTVNSSDLNFKYTNDSQNNSEKVDDYNNNYLVIDNPPTSDL
Sbjct: 1 MNLFNNFLRTFILLSINFLNNISAIKRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNYFHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILVKTENFKNIIIQNLYGATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCAKPRCKNGGKCIKSELKNDFICFCKNNYYGKNCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKLVSLNVETKKPIVESIPVSKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSSEENFRRWHSLDDNSFYLCNQGHVEPYHTYRSGSNVYPKHEQGIETCRDGYGSLNSSHRMCHSIMRTRMPVLCEPSTVNSSDLNFKYTNDSQNNSEKVDDYNNNYLVIDNPPTSDL 535
BLAST of Jagged-like vs. Planmine SMEST
Match: SMESG000025147.1 (SMESG000025147.1) HSP 1 Score: 112.079 bits (279), Expect = 5.520e-26 Identity = 112/421 (26.60%), Postives = 182/421 (43.23%), Query Frame = 1
Query: 151 KRAPGTLTLKIQTPAYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNY-FHKMPKYLAEISFEVDNVKDPFYFNANLSYFQNEILV--KTENFKNIIIQNLYGATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCE-KTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKFVSLNVETKKPIVESIPVSKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTYRSS-----EENFRRWHSLDDNSFYL 1386
+++P + L+ + + + K+ L C+ E+C W T N N H+ + F ++N+ + L + I KT N K I ++ + I ++F ++V+ +C+ G++P +C CF + Y CD G KIC G FD NKC +NC + +I C+NNG CV+ +C C++ +SG CE +PC C+N GKC N + C C+ + G C+ K ++C C +N C S+S + + SI P + P+ E P+ K N+ Q+ + N +TT IV IGCF V + Y ++++ YS S + S S + + E F+R SL+DNS YL
Sbjct: 34 QQSPAKVNLRFLISKFSQLLTSEPVKFSL--CIDKNH---EKCFW---TTNKNVELHEELFQEVQFEFYINNMDTNLSISIKLENGGSTINFSHKTINLKKISSKDTFELHSITLENFVKVTVEH--ECENGYYPAKQCNKFCFPSENEYTCDGFGNKICKEGLYFDADENKCLPNNCIASSIQCYNNGFCVNKGSTFECKCMESYSGKFCEFANPCFPNPCQNMGKCFIKPNGNAYFCNCRTGFAGDKCDFKVVQTC---KCPENMRCNY------------SESGV---LFSCTSINDDNRENP---------ENPLYEK-PIKKSENK--QNQNWNNVSSTTTIVAA-----IGCFMVLISIGVSVYVCQRTRNYS--SLIKSRTSEGTQSNFLNQYPPKFESTFKRSFSLEDNSAYL 407
BLAST of Jagged-like vs. Planmine SMEST
Match: SMESG000059836.1 (SMESG000059836.1) HSP 1 Score: 89.7373 bits (221), Expect = 6.616e-19 Identity = 70/258 (27.13%), Postives = 115/258 (44.57%), Query Frame = 1
Query: 106 FILLSINFLNNISAIKRAPGTLTLKIQTP----AYVEDCVEKYCKYVLKSCVGSGRSENERCLWSPLTVNSNYFHKMPKYLAE--ISFEVDNVKDPFYFNANLSYFQNEILVKTENF----------KNIIIQNL-YGATQIHSQDFATLSVDIVIKCKPGFFPKNRCLVSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKC 825
F+ +++ + A +APGT+T+ I+ Y +D V L S V + + E L ++ + E I F+V N+ + +N + QN +T F K+ ++ N+ Y +S+++ L V +KCK F+P+ C V C + ++ KCD NG KIC G+ F+ T C+ D C IC N+G CV+ +C C +SG C+I + C + C N C
Sbjct: 6 FVFVALGISSVGFARFQAPGTITMNIKYHPDIYLYGDDNV------TLDSTVNTTKMRRE------LYKKADRMKLLSDGALELTIKFDVYNISEHIDYNGLMKIMQNGRKTETYEFRLISFKFSTKKSFLLNNMRYVTATAYSKEYKELEVMTSVKCKQNFYPEFNCSVLCVKTQTIEKCDSNGNKICRKGFYFNDYTQTCDTDWCTQSKPICVNDGHCVNRRKESECVCGPLYSGKYCQIPLNLCQQHNCPNKTYC 251
BLAST of Jagged-like vs. Planmine SMEST
Match: SMESG000063217.1 (SMESG000063217.1) HSP 1 Score: 60.4622 bits (145), Expect = 3.361e-9 Identity = 52/156 (33.33%), Postives = 70/156 (44.87%), Query Frame = 1
Query: 619 CLSGYVFDPLTNKCNLDNCNS-ENIICFNNGTCVSGAHNPKCFCVDGFSGPSCE--IWDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEK-------------------------------TGKSCNDIT-------CEKNQFCEIVNNQ 963
C GY D +N ++D C S E +C N GTC++ + +C C GF+G CE I D CT CKNGG C+ + + C C NNY+G +CE TGK+C+D+ C+ N FCE VN Q
Sbjct: 161 CNKGYTGDTCSN--DIDECASYETPLCENGGTCINTVGSYQCKCKAGFNGERCENDIVD-CTNDTCKNGGTCL--DKIGSYRCVCPNNYFGTNCENKRTLCELKPCKNGGICRDFDEDYQCICGNQWTGKNCDDVKNPCKINPCKNNGFCESVNYQ 311 HSP 2 Score: 58.5362 bits (140), Expect = 1.618e-8 Identity = 37/96 (38.54%), Postives = 49/96 (51.04%), Query Frame = 1
Query: 664 LDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCE 948
+DNC + I CFN G+C++ KC C+ GF G +CEI + C C+N KCI +L ND+ C C GK+CE C C CE
Sbjct: 330 IDNC--QKISCFNGGSCINMIEGGKCNCLPGFEGNNCEINVNECENKPCQNNAKCI--DLNNDYTCDCPEGLTGKNCEINIDECTPNPCLNGARCE 421 HSP 3 Score: 55.8398 bits (133), Expect = 8.546e-8 Identity = 44/135 (32.59%), Postives = 61/135 (45.19%), Query Frame = 1
Query: 562 VSCFEEASVYKCDENGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDIT-CEKNQFCEIVNN 960
+SCF S E G+ CL G+ N C ++ EN C NN C+ ++ C C +G +G +CEI D CT C NG +C + F C C + G CE C +T C+ + C VNN
Sbjct: 336 ISCFNGGSCINMIEGGKCNCLPGFE----GNNCEINVNECENKPCQNNAKCIDLNNDYTCDCPEGLTGKNCEINIDECTPNPCLNGARC--EDRVGGFTCQCLQGFVGLRCETKSDICKQLTPCKTEEICLNVNN 464 HSP 4 Score: 51.9878 bits (123), Expect = 1.354e-6 Identity = 38/109 (34.86%), Postives = 54/109 (49.54%), Query Frame = 1
Query: 604 NGRKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIW-DPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITC 927
NG IC ++ + L+NC N C N TC + A +C CV GF+G CEI + C C N KCI + ND+ C C++ + GK+CE C + +C
Sbjct: 678 NGSFICKCSSQYEGRQCEKPLNNC--RNDPCRNGATCDNLADGFRCRCVAGFTGERCEIEINECQHNPCSNDAKCI--DHINDYQCICQSGFSGKNCEINDNDCTESSC 782 HSP 5 Score: 50.447 bits (119), Expect = 4.032e-6 Identity = 33/89 (37.08%), Postives = 46/89 (51.69%), Query Frame = 1
Query: 682 ENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEI-WDPCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFC 945
+NI+C N G CV + KC C+ GF G +CEI + C C++G +C +L ND++C C + GK CE C C N C
Sbjct: 488 KNIVCVN-GQCVDVNNEEKCICIPGFEGRTCEIEINECFNNPCQHGSQC--QDLFNDYLCICLPGFKGKKCEININECAHNPCGLNGQC 573 HSP 6 Score: 50.447 bits (119), Expect = 4.543e-6 Identity = 33/107 (30.84%), Postives = 55/107 (51.40%), Query Frame = 1
Query: 610 RKICLSGYVFDPLTNKCNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWD-PCTKPRCKNGGKCIKSELKNDFICFCKNNYYGKSCEKTGKSCNDITC 927
R C++G+ + +C ++ ++ C N+ C+ ++ +C C GFSG +CEI D CT+ C G+C+ + N F C C NY G +CE + C+ C
Sbjct: 720 RCRCVAGFTGE----RCEIEINECQHNPCSNDAKCIDHINDYQCICQSGFSGKNCEINDNDCTESSCLGHGQCV--DKVNGFECKCNENYIGTNCEHLKRPCDSNPC 820
BLAST of Jagged-like vs. Planmine SMEST
Match: SMESG000025423.1 (SMESG000025423.1) HSP 1 Score: 58.151 bits (139), Expect = 1.059e-8 Identity = 67/276 (24.28%), Postives = 98/276 (35.51%), Query Frame = 1
Query: 526 CKPGFFPKNRCLVSCFEEASVYKCDEN-GRKICLSGYVFDPLTNK--CNLDNCNSENIICFNNGTCVSGAHNPKCFCVDGFSGPSCEIWD-PCTKPRCKNGGKCI-----KSELKNDFICFCKNNYYGKSCEKTGKSCNDITCEKNQFCEIVNNQPKCSVKKNSKSFIQKTFVTPPSIKSTTITKPKFVSLNVETKKPIVESIPVSKGTNRLLQSHSLLNEYTTTAIVIVLVVFMIGCFGVTFWVLKIKYFQKKSKTYSNFSTLPVMPSIYNASTY 1326
CKP F K Y CD+N G+K CL G+ T + C LDN C + +C C C D G C+ PC C NGG C+ +E+ +C C N+ G++C+ C + C+ + C V C N V +KP V S+ KG + S + I+++LV M C +L + Y++ +SK + S V I N Y
Sbjct: 189 CKPSFSMK----------TGFYACDKNSGQKYCLIGWTGTNCTQRDMCVLDN------PCHGSASCSMNESVVNCICPDSLEGQYCQTSKRPCGSSPCLNGGLCVLHPIDSNEVSRKTVCVCPRNFTGETCQHDFNECKNSPCKNDANCVNVFGSYDCICLNN--------------------------HWGVNCEKPPVFSV---KGIDPAYFIKSSTARFMQNTIIVLLVTVM--CLIFIIGLLSLLYYRNRSKIIRSPSAGSVYSEIQNDEKY 417 The following BLAST results are available for this feature:
BLAST of Jagged-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Jagged-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Jagged-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Jagged-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Jagged-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Jagged-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Jagged-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Jagged-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Jagged-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Jagged-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Jagged-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Jagged-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Jagged-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Jagged-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031788 ID=SMED30031788|Name=Jagged-like|organism=Schmidtea mediterranea sexual|type=transcript|length=1779bpback to top protein sequence of SMED30031788-orf-1 >SMED30031788-orf-1 ID=SMED30031788-orf-1|Name=SMED30031788-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=536bp MNLFNNFLRTFILLSINFLNNISAIKRAPGTLTLKIQTPAYVEDCVEKYCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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