Metal transporter cnnm2

Overview
NameMetal transporter cnnm2
Smed IDSMED30031752
Length (bp)2118
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Metal transporter cnnm2 (SMED30031752) t-SNE clustered cells

Violin plots show distribution of expression levels for Metal transporter cnnm2 (SMED30031752) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30031752

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30031752h1SMcG0000438 SmedASXL_013389SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30031752h1SMcG0000438 dd_Smed_v4_18450_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4 [Source:HGNC Symbol;Acc:HGNC:105])

HSP 1 Score: 312.768 bits (800), Expect = 4.252e-95
Identity = 246/593 (41.48%), Postives = 372/593 (62.73%), Query Frame = 1
Query:  199 ENVVLIPARKPVNISLYGRNLSRVHS--VSFTSTNASQ--------FSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKE---KFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFE---KMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRS-LNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNK--DANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKS 1899
            + ++ +     VN+ LYG +L  + S  +SFT  + ++          L  +L   Q   V+  N  +   ++L  F  +    K + +C         +   + W     DKD ++ + E   + LP+WL I+LI +L  LSG+FSGLNLGLM+L   +L +    G+ +E++YA+ I PIR  GN+LL +LLLGNVLVN++LTIL+D+  G+GL+AV  ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK FM++TF +SFPI K+LD  LG+E+  VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +DIMT L + FMI   ++L+F+ +++I+ +G+TRIPV+E E++NI  +L +KDL  +DPDD  P+ T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +N  R R S  NK+DFS F +++     K++PQL L A + L  E+S F   LIS  +L  LL   +++ E+K++  NK    + +  ++K  ++ IL+L G+V V    EN+ FE+G F ++G   L S
Sbjct:   63 DGIIFVSEGSTVNLRLYGYSLGNISSNLISFTEVDDAETLHKSTSCLELTKDLVVQQLVNVSRGN-TSGVLVVLTKFLRRSESMKLYALC----TRAQPDGPWLKWT----DKDSLLFMVEEPGRFLPLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGLMAVASSTIGIVIFGEILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPISKLLDFFLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLQDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRSRKRVSEKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVSQFSPSLISEKILLRLLKYPDVIQELKFDEHNKYYARHYLYTRNKPADYFILILQGKVEVEAGKENMKFETGAFSYYGTMALTS 646          
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:HGNC Symbol;Acc:HGNC:103])

HSP 1 Score: 309.686 bits (792), Expect = 3.265e-93
Identity = 225/480 (46.88%), Postives = 327/480 (68.12%), Query Frame = 1
Query:  481 HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIFHE--SNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            H G D  +IV   +K +LP WL +I I LL  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y +  RT++ +     KQDFS F +  S    K++PQL L   + L  E+ +F    +S  +L  LL + N++ E+KY+  NK A    +  ++K +++ +L+L G+V V    E + FE+  F ++G
Sbjct:  236 HDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTD-NRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYG 714          
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:HGNC Symbol;Acc:HGNC:103])

HSP 1 Score: 309.301 bits (791), Expect = 6.424e-93
Identity = 225/480 (46.88%), Postives = 327/480 (68.12%), Query Frame = 1
Query:  481 HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIFHE--SNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            H G D  +IV   +K +LP WL +I I LL  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y +  RT++ +     KQDFS F +  S    K++PQL L   + L  E+ +F    +S  +L  LL + N++ E+KY+  NK A    +  ++K +++ +L+L G+V V    E + FE+  F ++G
Sbjct:  236 HDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTD-NRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYG 714          
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:HGNC Symbol;Acc:HGNC:103])

HSP 1 Score: 242.662 bits (618), Expect = 6.495e-71
Identity = 160/309 (51.78%), Postives = 224/309 (72.49%), Query Frame = 1
Query:  481 HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTH 1404
            H G D  +IV   +K +LP WL +I I LL  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKK  T+
Sbjct:  236 HDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKEHTN 544          
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Match: CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1 [Source:HGNC Symbol;Acc:HGNC:102])

HSP 1 Score: 237.269 bits (604), Expect = 3.007e-66
Identity = 150/367 (40.87%), Postives = 236/367 (64.31%), Query Frame = 1
Query:  823 GIVILG-EIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEG-ERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTR---RSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            G V LG EI P SV SR+ L I + ++ +T++ M   F V +P+G++LD  L +E+   Y+REKL   ++       +VK+E+NII GAL L TK  ++++T L + FM+   +VL+F  +++I+R+G+TRIPVYEG +R+NI  +L +KDL  +DPDD  P+ TV  FY RP+ CV + T L  +LEEFKKGK+HLA V   N     D   +++G+VTLED+IEEII++EI+DETD+Y +N ++ R   R   + DFS+F   ++    K++PQL L   + +  E+  F+   +S  +L  LL + N++ E+K++  NK A  + +  +++ +++ +LLL G+V V V  E L FE+G F ++G
Sbjct:  333 GAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYG 699          
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-1 (Metal transporter cnnm-1 [Source:UniProtKB/Swiss-Prot;Acc:A3QM97])

HSP 1 Score: 240.736 bits (613), Expect = 1.292e-68
Identity = 177/441 (40.14%), Postives = 276/441 (62.59%), Query Frame = 1
Query:  628 DLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYE-GERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFV-----TEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXYN---NEQRTRRSLNKQDFSIF--HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL--NANIVIEVKYNPLNKDA------NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            +L L I +G+ +E+K A  I P+R  GN LL +LLLGNV+VNS ++IL+ + T  G+ A+IGST+GIVI GEI+PQS+  +  L +GA T+ IT++F+ +TF +++P+ K+LD +LG E    Y R++L  L+K        V +E+ I  GA+ +  K  KD+MT +++ FM+P ++VLN   + +IV+ G+TRIPVY+ G++NN+  +L +KDL LLDPDDN  V TVC ++K P+  V + T L  +LE FKKG+ HLA V     T+  +  +   ++G+VTLED++EEI+QAEI DE DI +   N+ + ++  N+     F  HE+ QT  ++ QL++ ALQ L +    FR++ +  NVL+ L+  +A  V       +  DA        +  KD++ +  IL+L GR+ V +    + FE+GP+  FG  I+
Sbjct:  232 ELELVIKSGAIKEQKCAAKILPVRKKGNLLLCSLLLGNVIVNSAISILMGELT-TGIYALIGSTMGIVIFGEILPQSICVKKGLEVGAHTISITQLFIFLTFPIAWPVSKLLDCLLGDEYQ-AYDRKRLMELIKMSITDNGQVSNELKIAVGAMEIADKVVKDVMTKIEDVFMLPDTTVLNAKTVMEIVKMGYTRIPVYQYGDKNNVTDMLFVKDLALLDPDDNFTVKTVCGYHKHPVKFVMNDTPLPNLLEAFKKGEGHLAMVKRLINTDDKHDPSY-VLVGVVTLEDIVEEILQAEINDEFDIVSDNVNKVKIKKEQNRDATKYFGDHEAPQT-MISMQLQMVALQWLVSNERGFRQEFLDTNVLERLIRSSARRVDVSALMAMGDDAINVPRLAKVYTKDELSDKYILILEGRIQVTIGASGMMFEAGPWHHFGGEIM 668          
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-1 (Metal transporter cnnm-1 [Source:UniProtKB/Swiss-Prot;Acc:A3QM97])

HSP 1 Score: 240.736 bits (613), Expect = 1.292e-68
Identity = 177/441 (40.14%), Postives = 276/441 (62.59%), Query Frame = 1
Query:  628 DLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYE-GERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFV-----TEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXYN---NEQRTRRSLNKQDFSIF--HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL--NANIVIEVKYNPLNKDA------NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            +L L I +G+ +E+K A  I P+R  GN LL +LLLGNV+VNS ++IL+ + T  G+ A+IGST+GIVI GEI+PQS+  +  L +GA T+ IT++F+ +TF +++P+ K+LD +LG E    Y R++L  L+K        V +E+ I  GA+ +  K  KD+MT +++ FM+P ++VLN   + +IV+ G+TRIPVY+ G++NN+  +L +KDL LLDPDDN  V TVC ++K P+  V + T L  +LE FKKG+ HLA V     T+  +  +   ++G+VTLED++EEI+QAEI DE DI +   N+ + ++  N+     F  HE+ QT  ++ QL++ ALQ L +    FR++ +  NVL+ L+  +A  V       +  DA        +  KD++ +  IL+L GR+ V +    + FE+GP+  FG  I+
Sbjct:  232 ELELVIKSGAIKEQKCAAKILPVRKKGNLLLCSLLLGNVIVNSAISILMGELT-TGIYALIGSTMGIVIFGEILPQSICVKKGLEVGAHTISITQLFIFLTFPIAWPVSKLLDCLLGDEYQ-AYDRKRLMELIKMSITDNGQVSNELKIAVGAMEIADKVVKDVMTKIEDVFMLPDTTVLNAKTVMEIVKMGYTRIPVYQYGDKNNVTDMLFVKDLALLDPDDNFTVKTVCGYHKHPVKFVMNDTPLPNLLEAFKKGEGHLAMVKRLINTDDKHDPSY-VLVGVVTLEDIVEEILQAEINDEFDIVSDNVNKVKIKKEQNRDATKYFGDHEAPQT-MISMQLQMVALQWLVSNERGFRQEFLDTNVLERLIRSSARRVDVSALMAMGDDAINVPRLAKVYTKDELSDKYILILEGRIQVTIGASGMMFEAGPWHHFGGEIM 668          
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-3 (Metal transporter cnnm-3 [Source:UniProtKB/Swiss-Prot;Acc:A0A131MCZ8])

HSP 1 Score: 201.445 bits (511), Expect = 7.752e-55
Identity = 164/449 (36.53%), Postives = 254/449 (56.57%), Query Frame = 1
Query:  628 DLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVK--QQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFV---TEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXY--NNEQRTRRSLNKQDFS-IFHESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANI-VIEVKYNPLNKDANTIIPKDKVL-------NHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKSDLYTLLRKL 1926
            +L L+IA+G+ QEK+ A  I PIR  GN LL TLL+GNV+VN  +++L+D   G+G   ++ +T  IV+ GEIIPQ++  +  L IGA+T+ IT++ + + + +++PI K+LD  L +EL     R KL  ++K  ++ ++G    DE  ++ GAL L  KT    MT  ++ FM+P++  L   ++ QI+  G+TRIP+YE +R NI A+L +KDL LLDPDDN  V  + S Y   +  V     LR MLEEFK+G+ H+A V    E+  +  + ++ GL+TLED+IEEIIQ EIIDETD    N  ++ R+     D S I + ++    +  Q+    +Q +      F  + I   +L+ L+  N   +E       K+   + PK  VL       N  I++L GR  V +  E +  E+G +  FG  +L +    + R L
Sbjct:  228 ELQLYIASGTEQEKRDAGRILPIRKKGNQLLCTLLIGNVVVNVGVSLLMDQLVGSGFAVLVAATSCIVVFGEIIPQALCVKLGLPIGARTIPITQVLLFLMYPLTWPISKVLDIFLKEELTRSLERNKLVEMLKLSEKSIIGGQ-SDEFKMVLGALELYDKTVAHAMTRYEDIFMLPHTLTLGAGMVTQILDMGYTRIPIYENDRKNIVALLFVKDLALLDPDDNHNVMKIASIYNHEVRRVLVDMPLRNMLEEFKRGEYHMALVERLVEQEDKDPIYELCGLITLEDIIEEIIQCEIIDETDAVCDNVHRKKRQRKRNHDMSQIVNTAHAKCAINIQMLAVTIQVMSTCHKIFSSNYILPTILEKLIRKNCKKVETTQFSCLKEVGVVQPKPAVLFTKGEFSNKFIMILSGRAVVTIGKEEMRLEAGAWHSFGTEVLDAMAEAIERSL 675          
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-3 (Metal transporter cnnm-3 [Source:UniProtKB/Swiss-Prot;Acc:A0A131MCZ8])

HSP 1 Score: 201.445 bits (511), Expect = 1.134e-54
Identity = 164/449 (36.53%), Postives = 254/449 (56.57%), Query Frame = 1
Query:  628 DLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVK--QQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFV---TEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXY--NNEQRTRRSLNKQDFS-IFHESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANI-VIEVKYNPLNKDANTIIPKDKVL-------NHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKSDLYTLLRKL 1926
            +L L+IA+G+ QEK+ A  I PIR  GN LL TLL+GNV+VN  +++L+D   G+G   ++ +T  IV+ GEIIPQ++  +  L IGA+T+ IT++ + + + +++PI K+LD  L +EL     R KL  ++K  ++ ++G    DE  ++ GAL L  KT    MT  ++ FM+P++  L   ++ QI+  G+TRIP+YE +R NI A+L +KDL LLDPDDN  V  + S Y   +  V     LR MLEEFK+G+ H+A V    E+  +  + ++ GL+TLED+IEEIIQ EIIDETD    N  ++ R+     D S I + ++    +  Q+    +Q +      F  + I   +L+ L+  N   +E       K+   + PK  VL       N  I++L GR  V +  E +  E+G +  FG  +L +    + R L
Sbjct:  228 ELQLYIASGTEQEKRDAGRILPIRKKGNQLLCTLLIGNVVVNVGVSLLMDQLVGSGFAVLVAATSCIVVFGEIIPQALCVKLGLPIGARTIPITQVLLFLMYPLTWPISKVLDIFLKEELTRSLERNKLVEMLKLSEKSIIGGQ-SDEFKMVLGALELYDKTVAHAMTRYEDIFMLPHTLTLGAGMVTQILDMGYTRIPIYENDRKNIVALLFVKDLALLDPDDNHNVMKIASIYNHEVRRVLVDMPLRNMLEEFKRGEYHMALVERLVEQEDKDPIYELCGLITLEDIIEEIIQCEIIDETDAVCDNVHRKKRQRKRNHDMSQIVNTAHAKCAINIQMLAVTIQVMSTCHKIFSSNYILPTILEKLIRKNCKKVETTQFSCLKEVGVVQPKPAVLFTKGEFSNKFIMILSGRAVVTIGKEEMRLEAGAWHSFGTEVLDAMAEAIERSL 675          
BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Match: cnnm-2 (Metal transporter cnnm-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9GYL2])

HSP 1 Score: 199.134 bits (505), Expect = 4.165e-54
Identity = 208/671 (31.00%), Postives = 340/671 (50.67%), Query Frame = 1
Query:   85 MKPFLVLIIILTKI--ISPSMNHEPQLYGMTVH--LDSVSF----SENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTS--IILR-PFFDKEKFFYICLSHE----VNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKD--EVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNN---IKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTE------------------------------------KNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXY--NNEQRTRR--SLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEISSFR-------EDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            +K FL L+++   I  I   +   P + G+ +   +D+  F        +L+ A   V++ ++G  L  V  V+FT          D++  T  F V+      H    I+ +  F    + + ICL  E    + + D+ T   W         +    E  +P+W    ++ LLFS+S L SGL LGLM+L+  +L + + +GS +EKK+A  I PIR HGN LL T+++ NV+VN+ +T+L DD    GLIA + ST+GIV+ GEI+PQS+  +Y L +GA T++ITK FM + F +++P+GK+LDK  G ++ VV +R ++  ++K      A   D   + I  GA+ LT K+ +D+MTD+D+ FM+    VLN + + +I  +G+TRIPV+EG   N   +K +L + DL L+  D+NI V  V  F KR +  V     L  +++EFK G  HLA V +                                    +N   +   ++GL+TLED+ EE++QAEI DETD Y  ++ Q+ RR  +  K    +F    ++ +L+  +     + L  +   F        E+LI  N+ +      ++I    N  +     +     +    +L+L G+ ++  + ++L FE GP+  FGE IL+
Sbjct:    3 IKVFLRLLLLCAHIVCIDGKLEIRPVVSGVRIESDVDASGFLGYGDAGELLVEANTEVDLVIFGHGLENVEMVTFT----------DSVCVTSEFNVSESTFYIHKDMKIVFKYAFVAWPQPWRICLKSECHGLIQIDDDRT---WIQ------AVQSTHETFMPVWAQCAILCLLFSISALCSGLTLGLMALTPQELSILMKSGSQREKKHAAAIYPIRCHGNRLLCTVIIMNVIVNTGITLLFDDL-AEGLIAFVASTVGIVVFGEILPQSICVKYGLAVGANTIFITKFFMFLLFPITWPLGKILDKYAGVDIDVV-NRSRMVEMLKMNMENDACDIDLSTLKIAIGAMELTKKSVRDVMTDIDDVFMLSEDQVLNAETMTKISDSGYTRIPVFEGNNRNKVAVKNLLYVSDLALIGKDNNITVKAVARFNKRRLRIVDESMPLTALMDEFKLGDYHLAMVAKATEVKKHHHGKFADGTVDSFILKSMKLVEATMMPQVENPEDHPVTLVGLITLEDITEELLQAEITDETDCYVTDDAQKKRRTNTSKKSAAELFCSEKKSERLSLHMLEMTEKWLLEKTPLFGNMNPKAFENLIQRNIRE------VLIVPPKNSTSPGTLNLFEAGVMSKRFLLILEGKATIRFNEKDLIFECGPWTCFGEAILE 646          
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0346683)

HSP 1 Score: 321.242 bits (822), Expect = 5.382e-98
Identity = 245/594 (41.25%), Postives = 366/594 (61.62%), Query Frame = 1
Query:  154 QLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMH-NGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMV---WRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGK-THLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRS-LNKQDFSIFHESN--QTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            ++ G+ +  ++V     +  +   K     ++G  L    +++FT+        C         P+ +  NG +    +  P F  E  F+IC       T++S A       HQG    + +K FE ++P+WL II+I+     S LFSGLNLGLMS+   +L +    G+ +EKKYA  IAP+R+ GN+LL ++LLGNVLVNST TIL+D  T +GL AVI STL IV+ GEI PQ+V SR+ L IGAKT+ +TK  M IT  +S+P+ ++LDK+LG+E+G VY+RE+L+ LV+    +  + K+EVNII+GAL L  KT  D+MT +++AFM+   ++L+F+ +++I+ +G++RIPVY+G+R NI  +L IKDL  +D DDN P+ T+C FY+ P+  V     L  M  +FK+G   H+AFV   N   + D   + +GLVTLEDVIEE+IQAEI+DETD++ +N  +TRR+   K DFS F E    QT +++PQL L   Q+L   + +F++D+IS  +L+ LLN ++   +K    +KD  +  I  + K ++  +L+L GRV V +  E L FESGPF +FG   L
Sbjct:   57 RIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE--FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQAL 647          
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0302227)

HSP 1 Score: 321.242 bits (822), Expect = 5.382e-98
Identity = 245/594 (41.25%), Postives = 366/594 (61.62%), Query Frame = 1
Query:  154 QLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMH-NGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMV---WRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGK-THLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRS-LNKQDFSIFHESN--QTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            ++ G+ +  ++V     +  +   K     ++G  L    +++FT+        C         P+ +  NG +    +  P F  E  F+IC       T++S A       HQG    + +K FE ++P+WL II+I+     S LFSGLNLGLMS+   +L +    G+ +EKKYA  IAP+R+ GN+LL ++LLGNVLVNST TIL+D  T +GL AVI STL IV+ GEI PQ+V SR+ L IGAKT+ +TK  M IT  +S+P+ ++LDK+LG+E+G VY+RE+L+ LV+    +  + K+EVNII+GAL L  KT  D+MT +++AFM+   ++L+F+ +++I+ +G++RIPVY+G+R NI  +L IKDL  +D DDN P+ T+C FY+ P+  V     L  M  +FK+G   H+AFV   N   + D   + +GLVTLEDVIEE+IQAEI+DETD++ +N  +TRR+   K DFS F E    QT +++PQL L   Q+L   + +F++D+IS  +L+ LLN ++   +K    +KD  +  I  + K ++  +L+L GRV V +  E L FESGPF +FG   L
Sbjct:   57 RIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE--FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQAL 647          
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0302226)

HSP 1 Score: 321.242 bits (822), Expect = 5.382e-98
Identity = 245/594 (41.25%), Postives = 366/594 (61.62%), Query Frame = 1
Query:  154 QLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMH-NGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMV---WRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGK-THLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRS-LNKQDFSIFHESN--QTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            ++ G+ +  ++V     +  +   K     ++G  L    +++FT+        C         P+ +  NG +    +  P F  E  F+IC       T++S A       HQG    + +K FE ++P+WL II+I+     S LFSGLNLGLMS+   +L +    G+ +EKKYA  IAP+R+ GN+LL ++LLGNVLVNST TIL+D  T +GL AVI STL IV+ GEI PQ+V SR+ L IGAKT+ +TK  M IT  +S+P+ ++LDK+LG+E+G VY+RE+L+ LV+    +  + K+EVNII+GAL L  KT  D+MT +++AFM+   ++L+F+ +++I+ +G++RIPVY+G+R NI  +L IKDL  +D DDN P+ T+C FY+ P+  V     L  M  +FK+G   H+AFV   N   + D   + +GLVTLEDVIEE+IQAEI+DETD++ +N  +TRR+   K DFS F E    QT +++PQL L   Q+L   + +F++D+IS  +L+ LLN ++   +K    +KD  +  I  + K ++  +L+L GRV V +  E L FESGPF +FG   L
Sbjct:   57 RIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE--FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQAL 647          
BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Match: uex (gene:FBgn0262124 transcript:FBtr0334938)

HSP 1 Score: 321.242 bits (822), Expect = 5.382e-98
Identity = 245/594 (41.25%), Postives = 366/594 (61.62%), Query Frame = 1
Query:  154 QLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMH-NGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMV---WRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGK-THLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRS-LNKQDFSIFHESN--QTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            ++ G+ +  ++V     +  +   K     ++G  L    +++FT+        C         P+ +  NG +    +  P F  E  F+IC       T++S A       HQG    + +K FE ++P+WL II+I+     S LFSGLNLGLMS+   +L +    G+ +EKKYA  IAP+R+ GN+LL ++LLGNVLVNST TIL+D  T +GL AVI STL IV+ GEI PQ+V SR+ L IGAKT+ +TK  M IT  +S+P+ ++LDK+LG+E+G VY+RE+L+ LV+    +  + K+EVNII+GAL L  KT  D+MT +++AFM+   ++L+F+ +++I+ +G++RIPVY+G+R NI  +L IKDL  +D DDN P+ T+C FY+ P+  V     L  M  +FK+G   H+AFV   N   + D   + +GLVTLEDVIEE+IQAEI+DETD++ +N  +TRR+   K DFS F E    QT +++PQL L   Q+L   + +F++D+IS  +L+ LLN ++   +K    +KD  +  I  + K ++  +L+L GRV V +  E L FESGPF +FG   L
Sbjct:   57 RIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINE--FFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLT-SGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQAL 647          
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm4b (cyclin and CBS domain divalent metal cation transport mediator 4b [Source:ZFIN;Acc:ZDB-GENE-070705-181])

HSP 1 Score: 327.02 bits (837), Expect = 1.268e-100
Identity = 231/469 (49.25%), Postives = 326/469 (69.51%), Query Frame = 1
Query:  505 IVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY---NNEQRTRRSLNKQDFSIF-HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            +V+  + MLPIW  +ILI  L  LSG+FSGLNLGLM+L   +L +  + G+ +EKKYA+ I PIR  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK FM +TF +S+PI K+LD VLG+E+G VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +D+MT L+N FMI   +VL+F+ +++I+ +G+TRIPVYE ER NI  +L +KDL  +DPDD   + T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII+ EI+DE+D+Y    N ++   + NK+DFS F HES    K++PQL L A + L  E+S F    IS  +L  +L + +++ E+K+N  +K ++   +  + K +++ IL+L GRV V   NEN+ FE+GPF F+G
Sbjct:  160 VVEEKKSMLPIWFQVILICCLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKKYARKIEPIRRKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTIGIVIFGEIVPQALCSRHGLAVGANTIHVTKFFMFLTFPLSYPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEEMNMIQGALELRTKTVEDVMTPLNNCFMINSDAVLDFNTMSEIMESGYTRIPVYEDERTNIVDILFVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKCEILDESDLYTDNRNRKKVAHNKNKRDFSAFKHESESKVKISPQLLLAAHRFLATEVSLFSPSQISEKILLRILKHPDVIQEIKFNENDKKSSHHYLYLRGKPVDYFILILQGRVEVEAGNENMKFETGPFSFYG 628          
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm2a (cyclin and CBS domain divalent metal cation transport mediator 2a [Source:ZFIN;Acc:ZDB-GENE-050208-36])

HSP 1 Score: 326.25 bits (835), Expect = 4.919e-100
Identity = 256/607 (42.17%), Postives = 375/607 (61.78%), Query Frame = 1
Query:  181 DSVSFSENVVL-IPARKPVNISLYGRNLSRV--HSVSFTS--TNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFD--------------------KEKFFYICLS-HEVNVTDNSTAMVW-RHQGFDKDVIVKVFEK--MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            D VSF +   L +  R  V + +YG+N++      ++FT   +NA   SL          P +   G+  + II+ P  +                    K K +Y+C +       D+ +   W  H+G D  VIV V EK  +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FMI+TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F  +++I+ +G+TRIPVYEGER +I  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  ++      KQDFS F   E+    K++PQL L  L+ L  E+ SF    +S  +L  LL + N++ E+KY+  +K  +   +  ++K +++ IL+L G+V V    E + FE+G F ++G
Sbjct:   57 DEVSFMDRGFLRVSERSRVRLRVYGQNINNETWSKLAFTEHRSNAPAESLSPG-----DAPASHPCGIRSSDIIILPTMEVNRKTSGIIELEVKPLRKTEKSKTYYLCTAIGTPGAQDSWSEHTWVYHEGHDTKVIV-VEEKKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKHYAKAIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMILTFPASYPVSKLLDHVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMISGDAILDFATMSEIMESGYTRIPVYEGERCHIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKKIAHREKKQDFSAFKPTENELRVKISPQLLLATLRFLATEVESFSATQMSEKILLRLLKHPNVIQELKYDDKDKKMSEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFEAGAFSYYG 657          
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2b [Source:ZFIN;Acc:ZDB-GENE-090311-26])

HSP 1 Score: 318.931 bits (816), Expect = 2.562e-97
Identity = 236/511 (46.18%), Postives = 340/511 (66.54%), Query Frame = 1
Query:  403 DKEKFFYICLSHE----VNVTDNSTAMVW-RHQGFDKDVIVKVFEK--MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIF-HESNQTS-KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            ++ K +Y+C++          D  T   W  H G D  VIV V EK  +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YA+ I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD +LG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   + L+F+ +++I+ +G+TRIPV+EG+R+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  ++      KQDFS F H  N+   K++PQL L  L+ L  E+  F    +S  +L  LL + N++ EVKYN  NK A  + +  ++K +++ IL+L G+V V    E L FE+G F  +G
Sbjct:  160 ERSKAYYLCIATSTPAVAGAHDPWTENTWIYHDGEDTKVIV-VEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEKEKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGDATLDFNSMSEIMESGYTRIPVFEGDRSNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKKITHRERKQDFSAFKHMDNEMKVKISPQLLLATLRFLATEVEPFSPSQMSEKILLRLLKHPNVIQEVKYNDKNKKAIEHYLFHRNKPVDYFILVLQGKVEVEAGKEGLRFEAGAFSSYG 669          
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm4b (cyclin and CBS domain divalent metal cation transport mediator 4b [Source:ZFIN;Acc:ZDB-GENE-070705-181])

HSP 1 Score: 295.819 bits (756), Expect = 1.511e-90
Identity = 218/446 (48.88%), Postives = 303/446 (67.94%), Query Frame = 1
Query:  505 IVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY---NNEQRTRRSLNKQDFSIF-HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGR 1818
            +V+  + MLPIW  +ILI  L  LSG+FSGLNLGLM+L   +L +  + G+ +EKKYA+ I PIR  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK FM +TF +S+PI K+LD VLG+E+G VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +D+MT L+N FMI   +VL+F+ +++I+ +G+TRIPVYE ER NI  +L +KDL  +DPDD   + T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII+ EI+DE+D+Y    N ++   + NK+DFS F HES    K++PQL L A + L  E+S F    IS  +L  +L + +++ E+K+N            DK  +H  L L G+
Sbjct:  157 VVEEKKSMLPIWFQVILICCLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKKYARKIEPIRRKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTIGIVIFGEIVPQALCSRHGLAVGANTIHVTKFFMFLTFPLSYPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEEMNMIQGALELRTKTVEDVMTPLNNCFMINSDAVLDFNTMSEIMESGYTRIPVYEDERTNIVDILFVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKCEILDESDLYTDNRNRKKVAHNKNKRDFSAFKHESESKVKISPQLLLAAHRFLATEVSLFSPSQISEKILLRILKHPDVIQEIKFN----------ENDKKSSHHYLYLRGK 592          
BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2b [Source:ZFIN;Acc:ZDB-GENE-090311-26])

HSP 1 Score: 265.003 bits (676), Expect = 3.190e-79
Identity = 177/366 (48.36%), Postives = 252/366 (68.85%), Query Frame = 1
Query:  403 DKEKFFYICLSHE----VNVTDNSTAMVW-RHQGFDKDVIVKVFEK--MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTL 1470
            ++ K +Y+C++          D  T   W  H G D  VIV V EK  +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YA+ I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD +LG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   + L+F+ +++I+ +G+TRIPV+EG+R+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTL
Sbjct:  160 ERSKAYYLCIATSTPAVAGAHDPWTENTWIYHDGEDTKVIV-VEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEKEKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGDATLDFNSMSEIMESGYTRIPVFEGDRSNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTL 524          
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187])

HSP 1 Score: 327.791 bits (839), Expect = 5.023e-101
Identity = 224/490 (45.71%), Postives = 335/490 (68.37%), Query Frame = 1
Query:  451 TDNSTAMVWR-HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNN---EQRTRRSLNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            T     + W+ H G D  + V   EK +LPIWL   +I +L +LSG+FSGLNLGLM+L   +L +    G+ +EK+YA  I P+R  GN+LL +LLLGNVLVN+TLT L+D+  G+GL AV+ ST GIV+LGEI+PQ++ SR+ L +GA T+W+T+IFM++TF V++P+ ++LD  LG+E+G VY+REKL  ++K  +    +V++E+NII GAL L TKT +D+MT +++ FM+P  +VL+F+ ++ I+ +G+TRIPVYE ER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V S T L  +LEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +   ++R +R  +++DFS+F +++     K++PQL L A + L  E+  F   L+S   L  LL   ++V E+ +N  +K A  N +  + K+ ++ IL+L G+V V    EN+ FESG F ++G
Sbjct:  126 TSRGPGLPWKLHTGPDGRLRVLEEEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG 615          
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187])

HSP 1 Score: 328.561 bits (841), Expect = 7.300e-101
Identity = 224/491 (45.62%), Postives = 335/491 (68.23%), Query Frame = 1
Query:  448 VTDNSTAMVWR-HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNN---EQRTRRSLNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
             T     + W+ H G D  + V   EK +LPIWL   +I +L +LSG+FSGLNLGLM+L   +L +    G+ +EK+YA  I P+R  GN+LL +LLLGNVLVN+TLT L+D+  G+GL AV+ ST GIV+LGEI+PQ++ SR+ L +GA T+W+T+IFM++TF V++P+ ++LD  LG+E+G VY+REKL  ++K  +    +V++E+NII GAL L TKT +D+MT +++ FM+P  +VL+F+ ++ I+ +G+TRIPVYE ER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V S T L  +LEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +   ++R +R  +++DFS+F +++     K++PQL L A + L  E+  F   L+S   L  LL   ++V E+ +N  +K A  N +  + K+ ++ IL+L G+V V    EN+ FESG F ++G
Sbjct:  148 CTSRGPGLPWKLHTGPDGRLRVLEEEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG 638          
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187])

HSP 1 Score: 327.791 bits (839), Expect = 9.131e-101
Identity = 224/491 (45.62%), Postives = 335/491 (68.23%), Query Frame = 1
Query:  448 VTDNSTAMVWR-HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNN---EQRTRRSLNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
             T     + W+ H G D  + V   EK +LPIWL   +I +L +LSG+FSGLNLGLM+L   +L +    G+ +EK+YA  I P+R  GN+LL +LLLGNVLVN+TLT L+D+  G+GL AV+ ST GIV+LGEI+PQ++ SR+ L +GA T+W+T+IFM++TF V++P+ ++LD  LG+E+G VY+REKL  ++K  +    +V++E+NII GAL L TKT +D+MT +++ FM+P  +VL+F+ ++ I+ +G+TRIPVYE ER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V S T L  +LEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +   ++R +R  +++DFS+F +++     K++PQL L A + L  E+  F   L+S   L  LL   ++V E+ +N  +K A  N +  + K+ ++ IL+L G+V V    EN+ FESG F ++G
Sbjct:  156 CTSRGPGLPWKLHTGPDGRLRVLEEEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG 646          
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: cnnm4 (cyclin and CBS domain divalent metal cation transport mediator 4 [Source:NCBI gene;Acc:100145459])

HSP 1 Score: 315.464 bits (807), Expect = 7.616e-96
Identity = 230/511 (45.01%), Postives = 340/511 (66.54%), Query Frame = 1
Query:  403 DKEKFFYICLSHEVNVTDNS----TAMVW-RHQGFDKDVIVKVFEK--MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSLN---KQDFSIFHESNQTS--KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            +K K +Y+C S     +           W  H G D  VIV V EK  +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FM+   +VL+F+ +++I+ +G+TRIPVYEGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  ++ ++   KQDFS F +++     K++PQL L   + L  E+ +F    +S  +L  LL + N++ E+K++  NK +    +  ++K +++ +L+L G+V V    E + FE+G F ++G
Sbjct:  150 EKSKSYYLCTSISTPPSGGHPQPWAETTWIYHDGEDTKVIV-VEEKKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEREKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMMAGDAVLDFNTMSEIMESGYTRIPVYEGERSNIVDLLFVKDLAFVDPDDCTPLKTITRFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVMHRERKQDFSAFKQTDNEMKVKISPQLLLAMHRFLATEVDAFSPSQMSEKILLRLLKHPNVIQELKFDERNKKSAEYYLYQRNKPVDYFVLVLQGKVEVEAGKEGMKFEAGAFSYYG 659          
BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Match: ihh (indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187])

HSP 1 Score: 315.464 bits (807), Expect = 8.461e-96
Identity = 226/522 (43.30%), Postives = 338/522 (64.75%), Query Frame = 1
Query:  451 TDNSTAMVWR-HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNN---EQRTRRSLNKQDFSIFHESNQT--SKLAPQLKLTA-----------------------LQH---------LYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            T     + W+ H G D  + V   EK +LPIWL   +I +L +LSG+FSGLNLGLM+L   +L +    G+ +EK+YA  I P+R  GN+LL +LLLGNVLVN+TLT L+D+  G+GL AV+ ST GIV+LGEI+PQ++ SR+ L +GA T+W+T+IFM++TF V++P+ ++LD  LG+E+G VY+REKL  ++K  +    +V++E+NII GAL L TKT +D+MT +++ FM+P  +VL+F+ ++ I+ +G+TRIPVYE ER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V S T L  +LEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +   ++R +R  +++DFS+F +++     K++PQL L A                       L H         L++E+  F   L+S   L  LL   ++V E+ +N  +K A  N +  + K+ ++ IL+L G+V V    EN+ FESG F ++G
Sbjct:  149 TSRGPGLPWKLHTGPDGRLRVLEEEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTGEICFPPDSVPPLHNSPLPHYVMGYVPYVLFSEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG 670          
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm2 (cyclin M2 [Source:MGI Symbol;Acc:MGI:2151054])

HSP 1 Score: 309.301 bits (791), Expect = 3.121e-93
Identity = 225/480 (46.88%), Postives = 327/480 (68.12%), Query Frame = 1
Query:  481 HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIFHE--SNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            H G D  +IV   +K +LP WL +I I LL  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y +  RT++ +     KQDFS F +  S    K++PQL L   + L  E+ +F    +S  +L  LL + N++ E+KY+  NK A    +  ++K +++ +L+L G+V V    E + FE+  F ++G
Sbjct:  236 HDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTD-NRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYG 714          
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm2 (cyclin M2 [Source:MGI Symbol;Acc:MGI:2151054])

HSP 1 Score: 308.916 bits (790), Expect = 5.768e-93
Identity = 225/480 (46.88%), Postives = 327/480 (68.12%), Query Frame = 1
Query:  481 HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIFHE--SNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            H G D  +IV   +K +LP WL +I I LL  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y +  RT++ +     KQDFS F +  S    K++PQL L   + L  E+ +F    +S  +L  LL + N++ E+KY+  NK A    +  ++K +++ +L+L G+V V    E + FE+  F ++G
Sbjct:  236 HDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTD-NRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYG 714          
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm4 (cyclin M4 [Source:MGI Symbol;Acc:MGI:2151060])

HSP 1 Score: 304.679 bits (779), Expect = 3.245e-92
Identity = 240/590 (40.68%), Postives = 370/590 (62.71%), Query Frame = 1
Query:  199 ENVVLIPARKPVNISLYGRNLSRVHS--VSFTSTNASQ--------FSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKE--KFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFE---KMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSL-NKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            + ++ +     VN+ LYG +L  + S  +SFT  + ++          L  +L   +   V+  N      +I +     E  K + +C     +         W     DKD ++ + E   + LP+WL I+L+++L  LSG+FSGLNLGLM+L   +L +    G+ +E+KYA+ I PIR  GN+LL +LLLGNVLVN++LTIL+D+  G+G++AV  ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK+FM++TF +SFPI K+LD VLG+E+  VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +DIMT L + FMI   ++L+F+ +++I+ +G+TRIPV+E E++NI  +L +KDL  +DPDD  P+ T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +N  R R S+ NK+DFS F +++     K++PQL L A + L  E+  F   L+S  +L  LL   +++ E+++N  N+    + +  ++K  +  +L+L G+V V    EN+ FE+G F ++G   L
Sbjct:   60 DGIIFVSEGSTVNLRLYGHSLGDISSNLISFTEVDDAEAVHNSTNCLELTKDLVVQRLVNVSRGNTSGMLVVITKFLRRSENMKLYALCTRPRAD----GPWTRWT----DKDSLLFMVEEHGRFLPLWLHILLVMVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERKYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTIVLTKVFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLHDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRTRKRVSVKNKRDFSAFKDTDNELKVKISPQLLLAAHRFLATEVPQFSPSLMSEKILLRLLKYPDVIQELRFNEHNRYCVRHYLYTRNKPADCFVLILQGKVEVEAGKENMKFETGAFSYYGTMAL 641          
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm1 (cyclin M1 [Source:MGI Symbol;Acc:MGI:1891366])

HSP 1 Score: 238.039 bits (606), Expect = 1.206e-66
Identity = 151/367 (41.14%), Postives = 236/367 (64.31%), Query Frame = 1
Query:  823 GIVILG-EIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEG-ERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTR---RSLNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            G V LG EI P SV SR+ L I + ++ +T++ M   F V +P+G++LD  L +E+   Y+REKL   ++       +VK+E+NII GAL L TK  ++++T L + FM+   +VL+F  +++I+R+G+TRIPVYEG +R+NI  +L +KDL  +DPDD  P+ TV  FY RP+ CV + T L  +LEEFKKGK+HLA V   N     D   +++G+VTLED+IEEII++EI+DETD+Y +N ++ R   R   + DFS+F  S+     K++PQL L   + +  E+  F+   +S  +L  LL + N++ E+K++  NK A  + +  +++ +++ +LLL G+V V V  E L FE+G F ++G
Sbjct:  333 GAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYG 699          
BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Match: Cnnm1 (cyclin M1 [Source:MGI Symbol;Acc:MGI:1891366])

HSP 1 Score: 238.039 bits (606), Expect = 1.337e-66
Identity = 151/367 (41.14%), Postives = 236/367 (64.31%), Query Frame = 1
Query:  823 GIVILG-EIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEG-ERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTR---RSLNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            G V LG EI P SV SR+ L I + ++ +T++ M   F V +P+G++LD  L +E+   Y+REKL   ++       +VK+E+NII GAL L TK  ++++T L + FM+   +VL+F  +++I+R+G+TRIPVYEG +R+NI  +L +KDL  +DPDD  P+ TV  FY RP+ CV + T L  +LEEFKKGK+HLA V   N     D   +++G+VTLED+IEEII++EI+DETD+Y +N ++ R   R   + DFS+F  S+     K++PQL L   + +  E+  F+   +S  +L  LL + N++ E+K++  NK A  + +  +++ +++ +LLL G+V V V  E L FE+G F ++G
Sbjct:  333 GAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPHRERRRHDFSLFKLSDSEIRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDERNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYG 699          
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|A0JPA0|CNNM4_XENTR (Metal transporter CNNM4 OS=Xenopus tropicalis OX=8364 GN=cnnm4 PE=2 SV=1)

HSP 1 Score: 328.176 bits (840), Expect = 3.340e-100
Identity = 224/490 (45.71%), Postives = 335/490 (68.37%), Query Frame = 1
Query:  451 TDNSTAMVWR-HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNN---EQRTRRSLNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            T     + W+ H G D  + V   EK +LPIWL   +I +L +LSG+FSGLNLGLM+L   +L +    G+ +EK+YA  I P+R  GN+LL +LLLGNVLVN+TLT L+D+  G+GL AV+ ST GIV+LGEI+PQ++ SR+ L +GA T+W+T+IFM++TF V++P+ ++LD  LG+E+G VY+REKL  ++K  +    +V++E+NII GAL L TKT +D+MT +++ FM+P  +VL+F+ ++ I+ +G+TRIPVYE ER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V S T L  +LEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +   ++R +R  +++DFS+F +++     K++PQL L A + L  E+  F   L+S   L  LL   ++V E+ +N  +K A  N +  + K+ ++ IL+L G+V V    EN+ FESG F ++G
Sbjct:  149 TSRGPGLPWKLHTGPDGRLRVLEEEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYG 638          
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|Q6P4Q7|CNNM4_HUMAN (Metal transporter CNNM4 OS=Homo sapiens OX=9606 GN=CNNM4 PE=1 SV=3)

HSP 1 Score: 312.768 bits (800), Expect = 2.042e-94
Identity = 246/593 (41.48%), Postives = 372/593 (62.73%), Query Frame = 1
Query:  199 ENVVLIPARKPVNISLYGRNLSRVHS--VSFTSTNASQ--------FSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKE---KFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFE---KMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRS-LNKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNK--DANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKS 1899
            + ++ +     VN+ LYG +L  + S  +SFT  + ++          L  +L   Q   V+  N  +   ++L  F  +    K + +C         +   + W     DKD ++ + E   + LP+WL I+LI +L  LSG+FSGLNLGLM+L   +L +    G+ +E++YA+ I PIR  GN+LL +LLLGNVLVN++LTIL+D+  G+GL+AV  ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK FM++TF +SFPI K+LD  LG+E+  VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +DIMT L + FMI   ++L+F+ +++I+ +G+TRIPV+E E++NI  +L +KDL  +DPDD  P+ T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +N  R R S  NK+DFS F +++     K++PQL L A + L  E+S F   LIS  +L  LL   +++ E+K++  NK    + +  ++K  ++ IL+L G+V V    EN+ FE+G F ++G   L S
Sbjct:   63 DGIIFVSEGSTVNLRLYGYSLGNISSNLISFTEVDDAETLHKSTSCLELTKDLVVQQLVNVSRGN-TSGVLVVLTKFLRRSESMKLYALC----TRAQPDGPWLKWT----DKDSLLFMVEEPGRFLPLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGLMAVASSTIGIVIFGEILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPISKLLDFFLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLQDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRSRKRVSEKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVSQFSPSLISEKILLRLLKYPDVIQELKFDEHNKYYARHYLYTRNKPADYFILILQGKVEVEAGKENMKFETGAFSYYGTMALTS 646          
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|Q5U2P1|CNNM2_RAT (Metal transporter CNNM2 OS=Rattus norvegicus OX=10116 GN=Cnnm2 PE=2 SV=1)

HSP 1 Score: 310.842 bits (795), Expect = 1.043e-92
Identity = 224/480 (46.67%), Postives = 329/480 (68.54%), Query Frame = 1
Query:  481 HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIFHESNQTS--KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            H G D  +IV   +K +LP WL +I I LL  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y +  RT++ +     KQDFS F +++  +  K++PQL L   + L  E+ +F    +S  +L  LL + N++ E+KY+  NK A    +  ++K +++ +L+L G+V V    E + FE+  F ++G
Sbjct:  236 HDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTD-NRTKKKVAHRERKQDFSAFKQTDSETKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPECYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYG 714          
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|P0C588|CNNM4_RAT (Metal transporter CNNM4 OS=Rattus norvegicus OX=10116 GN=Cnnm4 PE=1 SV=1)

HSP 1 Score: 307.76 bits (787), Expect = 1.758e-92
Identity = 241/590 (40.85%), Postives = 368/590 (62.37%), Query Frame = 1
Query:  199 ENVVLIPARKPVNISLYGRNLSRVHS--VSFTSTNASQ--------FSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKE--KFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFE---KMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSL-NKQDFSIFHESNQT--SKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLN-ANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL 1893
            + ++ +     VN+ LYG  L  + S  +SFT  + ++          L  +L   +   V+  N      +I +     E  K + +C         +   + W     DKD ++ + E   + LP+WL I+L+++L  LSG+FSGLNLGLM+L   +L +    G+ +E++YA+ I PIR  GN+LL +LLLGNVLVN++LTIL+D+  G+G++AV  ST+GIVI GEI+PQ++ SR+ L +GA T+ +TKIFM++TF +SFPI K+LD VLG+E+  VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +DIMT L + FMI   ++L+F+ +++I+ +G+TRIPV+E E++NI  +L +KDL  +DPDD  P+ T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D Y +N  R R S+ NK+DFS F +++     K++PQL L A + L  E+  F   L+S  +L  LL   +++ E++++  NK      +  ++K  +  IL+L G+V V    EN+ FE+G F ++G   L
Sbjct:   61 DGIIFVSEGSTVNLRLYGHRLGEISSNLISFTEVDDAETVHNSTNCLELTKDLVVQRLVNVSRGNTSGMLVVITKFLRRSENMKLYALC----TRTRADGPWLKWT----DKDSLLFMVEEHGRFLPLWLHILLVLVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTIVLTKIFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLHDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDTYTDNRTRKRVSMKNKRDFSAFKDADNELKVKISPQLLLAAHRFLATEVPQFSPSLMSEKILLRLLKYPDVIQELRFDEHNKHCTRHYLYTRNKPADCFILILQGKVEVEAGKENMKFETGAFSYYGTMAL 642          
BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Match: sp|Q9H8M5|CNNM2_HUMAN (Metal transporter CNNM2 OS=Homo sapiens OX=9606 GN=CNNM2 PE=1 SV=2)

HSP 1 Score: 309.301 bits (791), Expect = 3.085e-92
Identity = 225/480 (46.88%), Postives = 327/480 (68.12%), Query Frame = 1
Query:  481 HQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIFHE--SNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDANT--IIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            H G D  +IV   +K +LP WL +I I LL  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R  GN+LL +LLLGNVLVN+TLTIL+DD  G+GL+AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER+NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y +  RT++ +     KQDFS F +  S    K++PQL L   + L  E+ +F    +S  +L  LL + N++ E+KY+  NK A    +  ++K +++ +L+L G+V V    E + FE+  F ++G
Sbjct:  236 HDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTD-NRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYG 714          
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A4S2LT86 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005039 PE=4 SV=1)

HSP 1 Score: 449.899 bits (1156), Expect = 5.013e-146
Identity = 300/619 (48.47%), Postives = 433/619 (69.95%), Query Frame = 1
Query:   91 PFLVLIIILTKIISPSMNHEPQLYGMTVHLDSV-SFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSII-LRPFFDKEKFFYICL------SHEVNVTDNSTAMVWRH---QGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            P   L+ IL  I + +M + P++YG+    D+V S S+N+VL+ + +PV ++L+G +L +V  ++F S      S CD  R+T++F ++  +    T++I LR     +  F++C+      +  ++++ N+++  W +   +GFD  +I +  + ++PIW+ IILII+LF LSGLFSGLNLGLMSL   +L +  +AGSP EK YAK I P+R  GN LL TLLLGNVLVN++LTIL+DD TG+GL AVIGST GI + GEI+PQ+V SR+ L +GA+T+W+TK+FM+ITF V+FPI  +LDK+LG+E+G VYSREKL +L+++Q L G V  DE+NIITGAL LTTKT  D+MT L +AFM+ YS+ L+F+ +N I  +G+TRIPV+E +R NI+AVLN+KDL  ++ DD +PV TVC FY R I+ V   T L  ML+EF++G+ H+AFV         D   ++IGLVTLEDVIEEIIQAEI+DETDI  +N     R + ++DF +F   E  + S+L+PQLK+ AL+HL + + SF+E L+ ++VL+S LN+NIV E  YNP ++++N +   ++  N+AIL+L GR    + NE L FE+GPF+ FGET+LK
Sbjct:   18 PLWTLLFIL-YIPAWTMGN-PKVYGILP--DTVLSVSDNIVLLQSNQPVLVTLFGTDLDQVSHIAFASVKKPPDSPCDIERSTETFRLSPKSPYVATTVIKLRELGMNDDGFFLCVRIIPTQTIGLSLSTNASSESWFYAGVEGFDNHLIFRTSKSLMPIWVQIILIIVLFFLSGLFSGLNLGLMSLDKTELKIIESAGSPNEKIYAKAIRPVREKGNLLLCTLLLGNVLVNTSLTILMDDLTGSGLFAVIGSTTGITLFGEIMPQAVCSRHGLAVGARTLWLTKLFMLITFPVAFPISFLLDKILGEEMGQVYSREKLGVLIREQALAGTVATDEMNIITGALALTTKTVADVMTPLSDAFMLSYSATLDFNTMNDIYAHGYTRIPVFEHDRRNIRAVLNVKDLAFINADDKVPVSTVCDFYNRSIIIVLDTTNLEAMLKEFRQGRAHMAFVERLVTEGEGDPYREMIGLVTLEDVIEEIIQAEIVDETDILTDNVHHQPRLVRRRDFRMFSMPEKQRHSRLSPQLKIAALRHLASNVESFQEHLVCYSVLQSFLNSNIVGECIYNPKDEESNILYLPNQWANYAILILQGRALCKIGNEGLLFEAGPFVMFGETVLK 632          
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A419PQF5 (Metal transporter CNNM2 (Fragment) OS=Clonorchis sinensis OX=79923 GN=Cnnm2 PE=4 SV=1)

HSP 1 Score: 446.817 bits (1148), Expect = 4.610e-145
Identity = 296/619 (47.82%), Postives = 433/619 (69.95%), Query Frame = 1
Query:   91 PFLVLIIILTKIISPSMNHEPQLYGMTVHLDSV-SFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSII-LRPFFDKEKFFYICL------SHEVNVTDNSTAMVWRH---QGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            P   L+ IL  I + +M + P++YG+    D+V S S+++VL+ + +P+ ++L+G +L ++  ++F S      S CD  R+T++F ++  +    T++I LR     +  F++C+      +  ++++ N+++  W +   +GFD  +I +  + ++PIW+ IILII+LF LSGLFSGLNLGLMSL   +L +  +AGSP EK YAK I P+R  GN LL TLLLGNVLVN++LTIL+DD TG+GL AVIGST GI + GEI+PQ+V SR+ L +GA+T+W+TK+FM+ITF V+FPI  +LDK+LG+E+G VYSREKL +L+++Q L G V  DE+NIITGAL LTTKT  D+MT L +AFM+ Y++ L+F+ +N I  +G+TRIPV+E +R NI+AVLN+KDL  ++ DD +PV TVC FY R I+ V   T L  ML+EF++G+ H+AFV         D   ++IGLVTLEDVIEEIIQAEI+DETDI  +N     R + ++DF +F   E  + S+L+PQLK+ AL+HL + + SF+E L+ ++VL+S LN+NIV E  YNP ++++N +   ++  N+AIL+L GR    + NE L FE+GPF+ FGET+LK
Sbjct:    8 PLWTLLFIL-YIPAWTMGN-PKVYGILP--DTVLSVSDSIVLLQSNQPILVTLFGTDLDQISHIAFASVKKPPDSPCDIERSTETFRLSPKSPYVATTVIKLRELGMNDDGFFLCVRIIPAQTPGLSLSTNASSESWFYAGVEGFDNHLIFRTSKSLMPIWVQIILIIVLFFLSGLFSGLNLGLMSLDKTELKIIESAGSPNEKIYAKAIRPVREKGNLLLCTLLLGNVLVNTSLTILMDDLTGSGLFAVIGSTTGITLFGEIMPQAVCSRHGLAVGARTLWLTKLFMLITFPVAFPISFLLDKILGEEMGQVYSREKLGVLIREQALAGTVATDEMNIITGALALTTKTVADVMTPLSDAFMLSYAATLDFNTMNDIYAHGYTRIPVFEHDRRNIRAVLNVKDLAFINADDKVPVSTVCDFYNRSIIIVLDTTNLEAMLKEFRQGRAHMAFVERLVTEGEGDPYREMIGLVTLEDVIEEIIQAEIVDETDILTDNVHHQPRLVRRRDFRMFSMPEKQRHSRLSPQLKIAALRHLASNVESFQEHLVCYSVLQSFLNSNIVGECIYNPKDEESNILYLPNQWANYAILILQGRALCKIGNEGLLFEAGPFVMFGETVLK 622          
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A4S2LT54 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005039 PE=4 SV=1)

HSP 1 Score: 450.284 bits (1157), Expect = 1.408e-143
Identity = 300/619 (48.47%), Postives = 433/619 (69.95%), Query Frame = 1
Query:   91 PFLVLIIILTKIISPSMNHEPQLYGMTVHLDSV-SFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSII-LRPFFDKEKFFYICL------SHEVNVTDNSTAMVWRH---QGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            P   L+ IL  I + +M + P++YG+    D+V S S+N+VL+ + +PV ++L+G +L +V  ++F S      S CD  R+T++F ++  +    T++I LR     +  F++C+      +  ++++ N+++  W +   +GFD  +I +  + ++PIW+ IILII+LF LSGLFSGLNLGLMSL   +L +  +AGSP EK YAK I P+R  GN LL TLLLGNVLVN++LTIL+DD TG+GL AVIGST GI + GEI+PQ+V SR+ L +GA+T+W+TK+FM+ITF V+FPI  +LDK+LG+E+G VYSREKL +L+++Q L G V  DE+NIITGAL LTTKT  D+MT L +AFM+ YS+ L+F+ +N I  +G+TRIPV+E +R NI+AVLN+KDL  ++ DD +PV TVC FY R I+ V   T L  ML+EF++G+ H+AFV         D   ++IGLVTLEDVIEEIIQAEI+DETDI  +N     R + ++DF +F   E  + S+L+PQLK+ AL+HL + + SF+E L+ ++VL+S LN+NIV E  YNP ++++N +   ++  N+AIL+L GR    + NE L FE+GPF+ FGET+LK
Sbjct:   18 PLWTLLFIL-YIPAWTMGN-PKVYGILP--DTVLSVSDNIVLLQSNQPVLVTLFGTDLDQVSHIAFASVKKPPDSPCDIERSTETFRLSPKSPYVATTVIKLRELGMNDDGFFLCVRIIPTQTIGLSLSTNASSESWFYAGVEGFDNHLIFRTSKSLMPIWVQIILIIVLFFLSGLFSGLNLGLMSLDKTELKIIESAGSPNEKIYAKAIRPVREKGNLLLCTLLLGNVLVNTSLTILMDDLTGSGLFAVIGSTTGITLFGEIMPQAVCSRHGLAVGARTLWLTKLFMLITFPVAFPISFLLDKILGEEMGQVYSREKLGVLIREQALAGTVATDEMNIITGALALTTKTVADVMTPLSDAFMLSYSATLDFNTMNDIYAHGYTRIPVFEHDRRNIRAVLNVKDLAFINADDKVPVSTVCDFYNRSIIIVLDTTNLEAMLKEFRQGRAHMAFVERLVTEGEGDPYREMIGLVTLEDVIEEIIQAEIVDETDILTDNVHHQPRLVRRRDFRMFSMPEKQRHSRLSPQLKIAALRHLASNVESFQEHLVCYSVLQSFLNSNIVGECIYNPKDEESNILYLPNQWANYAILILQGRALCKIGNEGLLFEAGPFVMFGETVLK 632          
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A3Q0KPE4 (Putative annexin OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 451.825 bits (1161), Expect = 4.652e-143
Identity = 305/631 (48.34%), Postives = 424/631 (67.19%), Query Frame = 1
Query:   85 MKPFLVLIIILTKII----SPSMNHEPQLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSII-LRPFFDKEKFFYICL----------SHEVNVTDNSTAMVWRHQGFDKDVI------VKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIF--HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            MK  ++LI++  K++    +P+   EP +YG+   + + S ++N++++P+ KP+++S++G  +  +  ++F S    + S C++ R T SF     N    TS+I LR   + E  F++C+              N TD     ++   G   D +       +    ++P+W+ IILIILLF LSGLFSGLNLGLMSL   +L +  +AGS  EK YAK I P+R  GN LL TLLLGNVLVN++LTIL+DD TGNGL AVIGST+GI +LGEI+PQ+V SR  L IGAKT+W+TK+FM++TF ++FPI  +LDK+LG+E+G VYSREKL +L+++Q L G V  DE+NIITGAL LTTKT  D+MT L +AFM+ YS+ L+F  +N+I  NG+TRIPVYE +R NI++VLN+KDL  ++ DD +PV TVC FY R I+ V   T L  ML+EF++G+ H+AFV       + D   ++IGLVTLEDVIEEIIQAEI+DETDI  +N     R + K+DF +F  H+S   S+L+PQLK+ AL+HL +E+ SF E  I ++VL+S LNANIV E  YNP + +ANT+    +  N+AILLL GR  V +  E L FE+GPF+ FGE +LK
Sbjct:    1 MKLDIILIMVFLKLLPIYCTPT---EPVIYGILPDIYN-SITDNIIVLPSNKPIHLSMFGLKMDYISHIAFASIKKPRNSSCEHERVTNSFDALPENSFVSTSVISLRELSNNEVAFFLCIRITPTSLPKADSTSNYTDIDGKWIFAGDGGGTDSVSDYRLSFRTTTTLMPLWVQIILIILLFFLSGLFSGLNLGLMSLDKTELKIIESAGSHNEKSYAKAIRPVREKGNLLLCTLLLGNVLVNTSLTILMDDLTGNGLFAVIGSTIGITLLGEIMPQAVCSRNGLAIGAKTLWLTKLFMLLTFPIAFPISFLLDKILGEEIGQVYSREKLGVLIREQALAGTVATDEMNIITGALALTTKTVADVMTPLSDAFMLSYSANLDFHTMNEIFSNGYTRIPVYENDRQNIRSVLNVKDLAFINTDDKVPVSTVCDFYNRSIIIVLDTTNLGMMLKEFRQGRAHMAFVERLVTEGDCDPYREMIGLVTLEDVIEEIIQAEIVDETDILTDNVHHQVRQVRKRDFRMFGLHDSQGKSRLSPQLKIAALRHLASEVKSFEEKYICYSVLQSFLNANIVGECIYNPKDDEANTLYHMGQWSNYAILLLQGRAVVQIGVEGLIFEAGPFLMFGEAVLK 627          
BLAST of Metal transporter cnnm2 vs. TrEMBL
Match: A0A074ZCH3 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_07446 PE=4 SV=1)

HSP 1 Score: 447.203 bits (1149), Expect = 1.538e-142
Identity = 295/619 (47.66%), Postives = 432/619 (69.79%), Query Frame = 1
Query:   94 FLVLIIILTKIISPSMN-HEPQLYGMTVHLDSV-SFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSII-LRPFFDKEKFFYICL------SHEVNVTDNSTAMVWRH---QGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            +L L  +L  + +P+     P++YG+    D+V S S+++VL+ + +P+ ++L+G +L ++  ++F S      S CD  R+T++F ++  +    T++I LR     +  F++C+      +  ++++ N+++  W +   +GFD  +I +  + ++PIW+ IILII+LF LSGLFSGLNLGLMSL   +L +  +AGSP EK YAK I P+R  GN LL TLLLGNVLVN++LTIL+DD TG+GL AVIGST GI + GEI+PQ+V SR+ L +GA+T+W+TK+FM+ITF V+FPI  +LDK+LG+E+G VYSREKL +L+++Q L G V  DE+NIITGAL LTTKT  D+MT L +AFM+ YS+ L+F+ +N I  +G+TRIPV+E +R NI+AVLN+KDL  ++ DD +PV TVC FY R I+ V   T L  ML+EF++G+ H+AFV         D   ++IGLVTLEDVIEEIIQAEI+DETDI  +N     R + ++DF +F   E  + S+L+PQLK+ AL+HL + + SF+E L+ ++VL+S LN+NIV E  YNP ++++N +   ++  N+AIL+L GR    + NE L FE+GPF+ FGET+LK
Sbjct:    6 YLPLWALLFILYTPAWTMGNPKVYGILP--DTVLSVSDSIVLLQSNQPILVTLFGTDLDQISHIAFASVKKPPDSPCDIERSTETFRLSPKSPYVATTVIKLRELGMNDDGFFLCVRIIPTQTPGLSLSANASSESWFYAGVEGFDNHLIFRTSKSLMPIWVQIILIIVLFFLSGLFSGLNLGLMSLDKTELKIIESAGSPNEKIYAKAIRPVREKGNLLLCTLLLGNVLVNTSLTILMDDLTGSGLFAVIGSTTGITLFGEIMPQAVCSRHGLAVGARTLWLTKLFMLITFPVAFPISFLLDKILGEEMGQVYSREKLGVLIREQALAGTVATDEMNIITGALALTTKTVADVMTPLSDAFMLSYSATLDFNTMNDIYAHGYTRIPVFEHDRRNIRAVLNVKDLAFINADDKVPVSTVCDFYNRSIIIVLDTTNLEAMLKEFRQGRAHMAFVERLVTEGEGDPYREMIGLVTLEDVIEEIIQAEIVDETDILTDNVHHQPRLVRRRDFRMFSMPEKQRHSRLSPQLKIAALRHLASNVESFQEHLVCYSVLQSFLNSNIVGECIYNPKDEESNILYLPNQWANYAILILQGRALCKIGNEGLLFEAGPFVMFGETVLK 622          
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2a (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:103036966])

HSP 1 Score: 330.102 bits (845), Expect = 1.083e-101
Identity = 251/608 (41.28%), Postives = 381/608 (62.66%), Query Frame = 1
Query:  181 DSVSFSENVVL-IPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQ-SFPVTMHN-GLAHTSIILRPFFD--------------------KEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKD--ANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKS 1899
            D VS+ +N  L +  R  V + +YG+N++        +   S+ +  ++ RNT   +   +H  G+  + II+ P  +                    K K +++C++ + +     +  V+ H+G D  V+V    K +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +E+ YAK I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FMI+TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  +R      KQDFS F   ++N   K++PQL L  L+ L  E+  F    +S  +L  LL + N++ E+KY+  NK    + +  ++K +++ IL+L G+V V    E + F++GPF ++G   L S
Sbjct:   67 DEVSYMDNGYLRVSERSRVKLRVYGQNIN--------NETWSKIAFTEHQRNTDYGYAPGLHPCGIRSSDIIILPSVEVNRRTSGVIEIDVKPLRKTEKSKLYHLCIATQDDEMRPESIWVY-HEGHDTKVLVVEERKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTERERNYAKYIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVASTIGIVIFGEIMPQAICSRHGLAVGANTIFLTKFFMILTFPASYPVSKLLDHVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIIGDAILDFNTMSEIMESGYTRIPVFEGERCNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRIAHRERKQDFSAFKPTDNNLGVKISPQLLLATLRFLATEVEPFGPAQMSEKILLRLLKHPNVIQELKYDDKNKKMLEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFKAGPFSYYGMMALTS 665          
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2a (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:103036966])

HSP 1 Score: 330.102 bits (845), Expect = 1.886e-101
Identity = 251/608 (41.28%), Postives = 381/608 (62.66%), Query Frame = 1
Query:  181 DSVSFSENVVL-IPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQ-SFPVTMHN-GLAHTSIILRPFFD--------------------KEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKD--ANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKS 1899
            D VS+ +N  L +  R  V + +YG+N++        +   S+ +  ++ RNT   +   +H  G+  + II+ P  +                    K K +++C++ + +     +  V+ H+G D  V+V    K +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +E+ YAK I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FMI+TF  S+P+ K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMI   ++L+F+ +++I+ +G+TRIPV+EGER NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  +R      KQDFS F   ++N   K++PQL L  L+ L  E+  F    +S  +L  LL + N++ E+KY+  NK    + +  ++K +++ IL+L G+V V    E + F++GPF ++G   L S
Sbjct:   67 DEVSYMDNGYLRVSERSRVKLRVYGQNIN--------NETWSKIAFTEHQRNTDYGYAPGLHPCGIRSSDIIILPSVEVNRRTSGVIEIDVKPLRKTEKSKLYHLCIATQDDEMRPESIWVY-HEGHDTKVLVVEERKFLLPFWLQVIFIAMLLCLSGMFSGLNLGLMALDPMELRIVQNCGTERERNYAKYIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVASTIGIVIFGEIMPQAICSRHGLAVGANTIFLTKFFMILTFPASYPVSKLLDHVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIIGDAILDFNTMSEIMESGYTRIPVFEGERCNIVDLLFVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRIAHRERKQDFSAFKPTDNNLGVKISPQLLLATLRFLATEVEPFGPAQMSEKILLRLLKHPNVIQELKYDDKNKKMLEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFKAGPFSYYGMMALTS 665          
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2b (metal transporter CNNM2-like [Source:NCBI gene;Acc:103025617])

HSP 1 Score: 316.235 bits (809), Expect = 9.465e-96
Identity = 232/508 (45.67%), Postives = 336/508 (66.14%), Query Frame = 1
Query:  403 DKEKFFYICL--SHEVNVTDNSTAMVW-RHQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFHESNQTS--KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            ++ K +Y+C+  S      D  T   W  H+G D  VIV    K +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YA+ I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  GNGLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD +LG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT  D+MT L + FMI   + L+F  +++I+ +G+TRIPV+E ER+NI  +L +KDL  +DPDD+ P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  +R      KQDFS F  ++     K++PQL L  L+ L  +I  F    IS  +L  LL + N++ E+K+N  NK A  + +  ++K +++ IL+L G+V V    + + FE+G F  +G
Sbjct:  202 ERSKAYYLCIATSTSAGTHDPWTESTWIYHEGEDTKVIVVEERKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGNGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVDDVMTPLRDCFMIASDATLDFGTMSEIMESGYTRIPVFEEERSNIVDLLFVKDLAFVDPDDSTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRITHRERKQDFSAFKPTDNEMKVKISPQLLLATLRFLATDIEPFSLVQISEKILLRLLKHPNVIQELKFNDKNKKALEHYLYVRNKPVDYFILILQGKVEVEAGKDGMKFEAGAFSSYG 709          
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2b (metal transporter CNNM2-like [Source:NCBI gene;Acc:103025617])

HSP 1 Score: 315.464 bits (807), Expect = 9.879e-96
Identity = 232/508 (45.67%), Postives = 336/508 (66.14%), Query Frame = 1
Query:  403 DKEKFFYICL--SHEVNVTDNSTAMVW-RHQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFHESNQTS--KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            ++ K +Y+C+  S      D  T   W  H+G D  VIV    K +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YA+ I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  GNGLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD +LG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT  D+MT L + FMI   + L+F  +++I+ +G+TRIPV+E ER+NI  +L +KDL  +DPDD+ P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  +R      KQDFS F  ++     K++PQL L  L+ L  +I  F    IS  +L  LL + N++ E+K+N  NK A  + +  ++K +++ IL+L G+V V    + + FE+G F  +G
Sbjct:  202 ERSKAYYLCIATSTSAGTHDPWTESTWIYHEGEDTKVIVVEERKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGNGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVDDVMTPLRDCFMIASDATLDFGTMSEIMESGYTRIPVFEEERSNIVDLLFVKDLAFVDPDDSTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRITHRERKQDFSAFKPTDNEMKVKISPQLLLATLRFLATDIEPFSLVQISEKILLRLLKHPNVIQELKFNDKNKKALEHYLYVRNKPVDYFILILQGKVEVEAGKDGMKFEAGAFSSYG 709          
BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Match: cnnm2b (metal transporter CNNM2-like [Source:NCBI gene;Acc:103025617])

HSP 1 Score: 311.612 bits (797), Expect = 8.239e-95
Identity = 232/508 (45.67%), Postives = 336/508 (66.14%), Query Frame = 1
Query:  403 DKEKFFYICL--SHEVNVTDNSTAMVW-RHQGFDKDVIVKVFEK-MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFHESNQTS--KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            ++ K +Y+C+  S      D  T   W  H+G D  VIV    K +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YA+ I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  GNGLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD +LG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT  D+MT L + FMI   + L+F  +++I+ +G+TRIPV+E ER+NI  +L +KDL  +DPDD+ P+ T+  FY  P+  V + T L  MLEEFKKGK+HLA V   N     D   +++G+VTLEDVIEEII++EI+DETD+Y + +  +R      KQDFS F  ++     K++PQL L  L+ L  E  S  +  IS  +L  LL + N++ E+K+N  NK A  + +  ++K +++ IL+L G+V V    + + FE+G F  +G
Sbjct:  158 ERSKAYYLCIATSTSAGTHDPWTESTWIYHEGEDTKVIVVEERKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYARKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGNGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVDDVMTPLRDCFMIASDATLDFGTMSEIMESGYTRIPVFEEERSNIVDLLFVKDLAFVDPDDSTPLKTITKFYSHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNKTKKRITHRERKQDFSAFKPTDNEMKVKISPQLLLATLRFLATEPFSLVQ--ISEKILLRLLKHPNVIQELKFNDKNKKALEHYLYVRNKPVDYFILILQGKVEVEAGKDGMKFEAGAFSSYG 663          
BLAST of Metal transporter cnnm2 vs. Ensembl Sea Lamprey
Match: cnnm4b (cyclin and CBS domain divalent metal cation transport mediator 4b [Source:ZFIN;Acc:ZDB-GENE-070705-181])

HSP 1 Score: 298.13 bits (762), Expect = 1.713e-90
Identity = 224/528 (42.42%), Postives = 328/528 (62.12%), Query Frame = 1
Query:  403 DKEKFFYICLSHEVNVTDNSTAMVW-RHQGFDKDV-IVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFV--TEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSLN---KQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLH--GRVSVLVSNENLYFESGPFIFFGETILKSD----LYTLLRKLCM 1932
            + E+ FY+C           T   W  H G D  + +V+    MLP WL I+ I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I PIR  GN+LL +LLLGNVLVN+TLTIL+DD  G+G++AVI ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK+FMI+TF  SFPI K+LD VLG+E+G VY+REKL  +++       +VK+E+NII GAL L  KT +D+MT L + FM+   +VL+F  +++I+++G+TRIPVYE E +N+  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKG+T+L +V   E +        +G++  E VI  +  A I     + ++ +  ++ L+   KQD+S F   ES    K++PQL L   + L AE+  F+   +S  +L  LL + N+  E+K++  N+ A  + +   +K +++ IL+L   G+V V V  E + FESG F +FG  IL S      Y+L R L +
Sbjct:  109 ETERLFYLCTKGIAGPAGLETGDNWVAHMGNDSRIAMVEERTSMLPRWLQILFIAVLLCLSGMFSGLNLGLMALDPMELRIVQNCGTAKEKAYAKKIEPIRRQGNYLLCSLLLGNVLVNTTLTILLDDLIGSGVVAVIASTVGIVIFGEIVPQALCSRHGLAVGANTIVLTKLFMILTFPASFPISKLLDVVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRVKTVEDVMTPLKDCFMLSADAVLDFGTMSEIMQSGYTRIPVYEDELSNVVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGETYLRYVGKVESSGTGTSGHFVGVLAPEQVIPVLPCAVIQGSRFLISDNKSKKKVLHRERKQDYSAFKPSESQTKIKISPQLLLATHRFLAAELEPFKPVQVSEKILLRLLKHPNVFQEIKFDEKNRKAPEHYLYQHNKPVDYFILVLQTKGKVEVEVGKEGMKFESGAFSYFGIPILTSSPPTVPYSLSRTLVL 636          
BLAST of Metal transporter cnnm2 vs. Ensembl Yeast
Match: MAM3 (Protein required for normal mitochondrial morphology; has similarity to hemolysins [Source:SGD;Acc:S000005421])

HSP 1 Score: 138.658 bits (348), Expect = 1.527e-34
Identity = 101/284 (35.56%), Postives = 162/284 (57.04%), Query Frame = 1
Query:  631 LHLFIAAGSPQEKKYAK-IIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGA--VVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVY-EGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTL 1470
            L +   +GS  EKK AK ++  I    +++L TLLL NV+ N TL I++D   G G  AV+ ST+ IVI GEIIPQSV  +Y L +GA       + M + + V++PI  +LD +LG++ G +Y +  L+ LV   + MG   + KDEV II+  L+L  K  ++IMT ++N F +   ++L+   + +I  +GF+RIP++   E NN   +L ++ L   DPDD +P   +  F    +   S  T    +L  F++GK H+  V+++   ++    IG++TL
Sbjct:   93 LKVISTSGSNSEKKLAKRVLDLISRGKHWVLVTLLLSNVITNETLPIVLDRCLGGGWQAVVSSTILIVIFGEIIPQSVCVKYGLQVGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLHRTMGVERLTKDEVTIISAVLDLKAKRVEEIMTPIENVFTMSADTILDDKTVEKIFNSGFSRIPIFLPNEPNNFIGMLLVRVLISYDPDDCLP---ISHFPLATLPETSPNTSCLNILNYFQEGKAHMCVVSKEPGSSH--GAIGVLTL 371          
BLAST of Metal transporter cnnm2 vs. Ensembl Nematostella
Match: EDO48694 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIF4])

HSP 1 Score: 306.605 bits (784), Expect = 1.163e-95
Identity = 198/444 (44.59%), Postives = 289/444 (65.09%), Query Frame = 1
Query:  628 DLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKY-NPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETIL--KSDLYTLLRKLCMHI 1938
            +L + I +GSP E+KYAK I PIR HGN+LL TLL GNVLVN++ T+L+D   GNG++AV+GST GIVI GEI+PQSV SR+ L +GA T+WITKIFM +TF +S+PI ++LD VLGKELG +Y++++L  ++K       + +DE+NII+GALN   KT +++MT L++ F++  +S L+F  +  I+++G +RIPVYE ER+N+  +L +KDL  +DPDD  P+ TV  FY  P+  V   T L  +LEEFKK  +HLA V   N     D   + IG+VTLED++EEIIQ+EI+DETD+Y +N+        K DF+ F +  +  K++PQL L   Q+L   +  F ED+IS  VLK L+  +I+ E++  +  +K    +  +    +  +L+L G+V V V  E   FE GPF  FG   L   S+++   + L  ++
Sbjct:    7 ELKIVINSGSPSEQKYAKKIDPIRRHGNYLLCTLLFGNVLVNTSFTVLLDSLIGNGIVAVLGSTAGIVIFGEIVPQSVCSRHGLKVGATTIWITKIFMFLTFPLSYPISRILDCVLGKELGTIYNKKQLLEMIKVTDEYNDLEEDEMNIISGALNYRNKTVQEVMTRLEDCFLVNVNSALDFRTMAWIMQSGHSRIPVYEDERHNVVGLLFVKDLAFVDPDDCTPLQTVIKFYNHPVQRVFDDTHLDVLLEEFKKKHSHLAIVERVNDTGEGDPFYEAIGIVTLEDILEEIIQSEIVDETDVYLDNKSGKVVPGRKPDFAFFSQDRERVKISPQLALAVFQYLSTAVDVFHEDIISTAVLKRLIEQDIITEIQLGDKSDKKEVYLYKRGTPADFFVLILQGKVEVNVGQEQFVFEEGPFTHFGGMALVNSSNIHGSTKTLAQYV 450          
BLAST of Metal transporter cnnm2 vs. Ensembl Nematostella
Match: EDO30992 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ75])

HSP 1 Score: 134.806 bits (338), Expect = 6.587e-34
Identity = 97/285 (34.04%), Postives = 152/285 (53.33%), Query Frame = 1
Query:  631 LHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVK-QQQLMGA----VVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTL 1470
            L + +  G   E+K+AK I P+    + LL TLLL N      + I +D  + + +IA+  S   ++  GE++PQ++ +RY L IGA      KI +I+ F+V++PI K+LD +LG E    + R +L+ LV   ++   A    +  DEV II GAL++  K  +D  T LD  FM+     L+  L+ +I+  G +R+PVYEG R NI  ++ +K L  LDP D   V  V       ++       L E+L++F+ GK+H+  V    Y   +  +IG  TL
Sbjct:   66 LKVLMRGGKINERKHAKKILPLVEQHHLLLVTLLLANAAAVEAMPIFMDRIS-SPVIAICVSVTAVLFFGEVVPQALCTRYGLAIGACMAPFVKILIILLFIVAWPISKLLDCLLGNEHSTFFRRAELKELVDLHKEGTDANEEPLRDDEVLIIQGALDMRNKRIRDRYTPLDRTFMLSVDDKLDDSLMLKIIAKGHSRVPVYEGSRENIVGLILVKSLIRLDPKDATLVRGVYRPRDGSLLASHVDEPLFELLDKFQTGKSHMCVV----YGKAVGDVIGKRTL 345          
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm4b (metal transporter CNNM4 [Source:NCBI gene;Acc:105354685])

HSP 1 Score: 333.183 bits (853), Expect = 6.631e-103
Identity = 235/470 (50.00%), Postives = 338/470 (71.91%), Query Frame = 1
Query:  505 IVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIF-HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNV-LKSLLNANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            +V+  + +LPIWL +ILI LL  LSG+FSGLNLGLM+L   +L +  + G+ +EK+YA+ I PIR+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GL AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK+FM++TF +S+PI K+LD VLG+E+G VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +D+MT L++ FMI   +VL+F+ +++I+ +G+TRIPVYEGER+NI  +L +KDL  +DPDD   + T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +  R+R+ +    NK+DFS F HES    K++PQL L A + L  E+S F ++ IS  V L+ L + ++V E+K+N  +K +  + I  K K +++ IL+L GRV V   NEN+ FE+GPF ++G
Sbjct:  171 VVEEAKSLLPIWLQVILISLLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKRYARKIEPIRSKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTVGIVIFGEIVPQALCSRHGLAVGANTIMLTKLFMLLTFPLSWPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEELNMIQGALELRTKTVEDVMTPLNDCFMIHSDAVLDFNTMSEIMESGYTRIPVYEGERSNIMDILYVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDLYTD-NRSRKKVAPNKNKRDFSAFKHESESKVKISPQLLLAAHRFLATEVSVFLQNQISDKVLLRILRHPDVVQEIKFNENDKRSLHHYIYQKGKPVDYFILILQGRVEVEAGNENMKFETGPFSYYG 639          
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm4b (metal transporter CNNM4 [Source:NCBI gene;Acc:105354685])

HSP 1 Score: 332.798 bits (852), Expect = 1.466e-102
Identity = 235/470 (50.00%), Postives = 338/470 (71.91%), Query Frame = 1
Query:  505 IVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIF-HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            +V+  + +LPIWL +ILI LL  LSG+FSGLNLGLM+L   +L +  + G+ +EK+YA+ I PIR+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GL AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK+FM++TF +S+PI K+LD VLG+E+G VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +D+MT L++ FMI   +VL+F+ +++I+ +G+TRIPVYEGER+NI  +L +KDL  +DPDD   + T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +  R+R+ +    NK+DFS F HES    K++PQL L A + L  E+S F ++ IS  VL  +L + ++V E+K+N  +K +  + I  K K +++ IL+L GRV V   NEN+ FE+GPF ++G
Sbjct:  171 VVEEAKSLLPIWLQVILISLLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKRYARKIEPIRSKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTVGIVIFGEIVPQALCSRHGLAVGANTIMLTKLFMLLTFPLSWPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEELNMIQGALELRTKTVEDVMTPLNDCFMIHSDAVLDFNTMSEIMESGYTRIPVYEGERSNIMDILYVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDLYTD-NRSRKKVAPNKNKRDFSAFKHESESKVKISPQLLLAAHRFLATEVSVFLQNQISDKVLLRILRHPDVVQEIKFNENDKRSLHHYIYQKGKPVDYFILILQGRVEVEAGNENMKFETGPFSYYG 639          
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm4b (metal transporter CNNM4 [Source:NCBI gene;Acc:105354685])

HSP 1 Score: 332.798 bits (852), Expect = 2.219e-102
Identity = 235/470 (50.00%), Postives = 338/470 (71.91%), Query Frame = 1
Query:  505 IVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRRSL----NKQDFSIF-HESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNV-LKSLLNANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            +V+  + +LPIWL +ILI LL  LSG+FSGLNLGLM+L   +L +  + G+ +EK+YA+ I PIR+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GL AV+ ST+GIVI GEI+PQ++ SR+ L +GA T+ +TK+FM++TF +S+PI K+LD VLG+E+G VY+REKL  ++K  +    +VK+E+N+I GAL L TKT +D+MT L++ FMI   +VL+F+ +++I+ +G+TRIPVYEGER+NI  +L +KDL  +DPDD   + T+  FY  P+  V   T L  MLEEFKKGK+HLA V + N     D   +++GLVTLEDVIEEII++EI+DE+D+Y +  R+R+ +    NK+DFS F HES    K++PQL L A + L  E+S F ++ IS  V L+ L + ++V E+K+N  +K +  + I  K K +++ IL+L GRV V   NEN+ FE+GPF ++G
Sbjct:  171 VVEEAKSLLPIWLQVILISLLLVLSGMFSGLNLGLMALDPMELRIVQSCGTDKEKRYARKIEPIRSKGNYLLCSLLLGNVLVNTTLTILLDDLIGSGLGAVVASTVGIVIFGEIVPQALCSRHGLAVGANTIMLTKLFMLLTFPLSWPISKLLDCVLGQEIGTVYNREKLVGMLKVTEPYNDLVKEELNMIQGALELRTKTVEDVMTPLNDCFMIHSDAVLDFNTMSEIMESGYTRIPVYEGERSNIMDILYVKDLAFVDPDDCTTLKTITKFYNHPVHFVFHDTKLDSMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDLYTD-NRSRKKVAPNKNKRDFSAFKHESESKVKISPQLLLAAHRFLATEVSVFLQNQISDKVLLRILRHPDVVQEIKFNENDKRSLHHYIYQKGKPVDYFILILQGRVEVEAGNENMKFETGPFSYYG 639          
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:101175055])

HSP 1 Score: 317.005 bits (811), Expect = 8.668e-97
Identity = 234/511 (45.79%), Postives = 347/511 (67.91%), Query Frame = 1
Query:  403 DKEKFFYICLSHEVNVT----DNSTAMVW-RHQGFDKDVIVKVFEK--MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFHESNQTS--KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            ++ K +Y+C++   +      D  T   W  H G D  VIV V EK  +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD +LG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMIP  + L+F+ +++I+++G+TRIPV+EGE++NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+H+A V   N     D   +++G+VTLED+IEEII++EI+DETD+Y + +  ++      KQDFS F  S+     K++PQL L AL+ L  E+  F ++ +S  +L  LL + N++ ++KY+  NK A  + +  ++K +++ IL+L G+V V    E + FE+GPF F+G
Sbjct:  157 ERSKAYYLCIATSASAAAGTHDPWTENTWIYHDGEDTKVIV-VEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYAKKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIPGDTTLDFNTMSEIMKSGYTRIPVFEGEKSNIVDLLLVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDTMLEEFKKGKSHMAIVQRVNNEGEGDPFYEVLGIVTLEDIIEEIIKSEILDETDLYTDNKSKKKITHRERKQDFSAFKPSDNEMKVKISPQLLLAALRFLATEVEPFYQEQMSQKILLRLLKHPNVIQDLKYDDNNKRAPEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFEAGPFSFYG 666          
BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Match: cnnm2b (cyclin and CBS domain divalent metal cation transport mediator 2 [Source:NCBI gene;Acc:101175055])

HSP 1 Score: 317.005 bits (811), Expect = 1.108e-95
Identity = 234/511 (45.79%), Postives = 347/511 (67.91%), Query Frame = 1
Query:  403 DKEKFFYICLSHEVNVT----DNSTAMVW-RHQGFDKDVIVKVFEK--MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXXYNNEQRTRR---SLNKQDFSIFHESNQTS--KLAPQLKLTALQHLYAEISSFREDLISFNVLKSLL-NANIVIEVKYNPLNKDA--NTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFG 1881
            ++ K +Y+C++   +      D  T   W  H G D  VIV V EK  +LP WL +I I +L  LSG+FSGLNLGLM+L   +L +    G+ +EK YAK I P+R+ GN+LL +LLLGNVLVN+TLTIL+DD  G+GLIAV+ ST+GIVI GEI+PQ++ SR+ L +GA T+++TK FM++TF  S+P+ K+LD +LG+E+G VY+REKL  +++       +VK+E+NII GAL L TKT +D+MT L + FMIP  + L+F+ +++I+++G+TRIPV+EGE++NI  +L +KDL  +DPDD  P+ T+  FY  P+  V + T L  MLEEFKKGK+H+A V   N     D   +++G+VTLED+IEEII++EI+DETD+Y + +  ++      KQDFS F  S+     K++PQL L AL+ L  E+  F ++ +S  +L  LL + N++ ++KY+  NK A  + +  ++K +++ IL+L G+V V    E + FE+GPF F+G
Sbjct:  255 ERSKAYYLCIATSASAAAGTHDPWTENTWIYHDGEDTKVIV-VEEKKFLLPFWLQVIFISMLLCLSGMFSGLNLGLMALDPMELQIVQNCGTEREKNYAKKIEPVRSQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLIAVVMSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMLLTFPASYPVSKLLDYLLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMIPGDTTLDFNTMSEIMKSGYTRIPVFEGEKSNIVDLLLVKDLAFVDPDDCTPLKTITKFYSHPLHFVFNDTKLDTMLEEFKKGKSHMAIVQRVNNEGEGDPFYEVLGIVTLEDIIEEIIKSEILDETDLYTDNKSKKKITHRERKQDFSAFKPSDNEMKVKISPQLLLAALRFLATEVEPFYQEQMSQKILLRLLKHPNVIQDLKYDDNNKRAPEHYLFHRNKPVDYFILILQGKVEVEAGKEGMKFEAGPFSFYG 764          
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000070597.1 (SMESG000070597.1)

HSP 1 Score: 1056.2 bits (2730), Expect = 0.000e+0
Identity = 572/607 (94.23%), Postives = 578/607 (95.22%), Query Frame = 1
Query:   79 FDMKPFLVLIIILTKIISPSMNHEPQLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            F MKPF VLIIILTK+ISPSMNHEPQLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPI  + + ++ L                    DLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLEDVIEEIIQAEIIDETDIY +NEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEI SFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK
Sbjct:    2 FSMKPFSVLIIILTKVISPSMNHEPQLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPICGLNLGLMSLSIN-----------------DLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLEDVIEEIIQAEIIDETDIYTDNEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEIISFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 591          
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000070597.1 (SMESG000070597.1)

HSP 1 Score: 1023.08 bits (2644), Expect = 0.000e+0
Identity = 555/587 (94.55%), Postives = 560/587 (95.40%), Query Frame = 1
Query:  139 MNHEPQLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            MNHEPQLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPI  + + ++ L                    DLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLEDVIEEIIQAEIIDETDIY +NEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEI SFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK
Sbjct:    1 MNHEPQLYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPICGLNLGLMSLSIN-----------------DLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLEDVIEEIIQAEIIDETDIYTDNEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEIISFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 570          
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000070597.1 (SMESG000070597.1)

HSP 1 Score: 1001.89 bits (2589), Expect = 0.000e+0
Identity = 546/578 (94.46%), Postives = 551/578 (95.33%), Query Frame = 1
Query:  166 MTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            MTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPI  + + ++ L                    DLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLEDVIEEIIQAEIIDETDIY +NEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEI SFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK
Sbjct:    1 MTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLPICGLNLGLMSLSIN-----------------DLHLFIAAGSPQEKKYAKIIAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQIIGLVTLEDVIEEIIQAEIIDETDIYTDNEQRTRRSLNKQDFSIFHESNQTSKLAPQLKLTALQHLYAEIISFREDLISFNVLKSLLNANIVIEVKYNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 561          
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000047046.1 (SMESG000047046.1)

HSP 1 Score: 462.611 bits (1189), Expect = 2.580e-152
Identity = 304/575 (52.87%), Postives = 413/575 (71.83%), Query Frame = 1
Query:  202 NVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKF-FYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEK--MLPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLDQ---IIGLVTLXXXXXXXXXXXXXXXXXXY-NNEQRTRRSLNKQDFSIFH--ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKY-NPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILK 1896
            +++ IP++   +  LYG  L++V  ++F+   ++    CD  R T ++PVT  +    T  +      KE F  Y C   + N T NS    W +Q  +  +  + +EK  +LP+W+ I +II+LF+LSGLFSGLN+GLM+L I +L +   AGS  +K+YAKII PIR  GNFLL TLLLGNVLVN+TL IL+DD TG+GL+AVI ST+GIVILGEIIPQ++ +R+AL IGAKT+WITK FM++T ++S+PIGK+LD +LGKELG VYSR +LE+LVK+QQL+G+VVKDE  II GAL LTTK  KDIMT L + FMI  +S+L+FD +N+IVRNGFTR+P+YEGER+NIKAVLN+KDL  +DPDD IPV TVC+FY R I+ V   T LR ML +F++GK H+AFV       + D    +IGLVTLEDVIEEIIQAEI+DETD++ +N ++ RR +  QDFS+F+  E+ +  +L+PQLK+ AL+HL + +  F ED I+ NVL+SLLNANI++E  + + ++   N I  K K  N+AIL+L G+    VS E+L FE+GPF+ FGE++ K
Sbjct:   58 SIIEIPSQIETDFELYGTYLTKVKYIAFSLIPSNWTDNCDTRRVTVAYPVTHFSDYIATVKVKIDTVWKENFRLYFCSKIQTNST-NSQISQWIYQSSETSLTFRTYEKKSLLPLWMQISIIIILFTLSGLFSGLNIGLMALDITELKIIEQAGSTNDKRYAKIIRPIRKRGNFLLCTLLLGNVLVNNTLAILMDDLTGSGLMAVIVSTIGIVILGEIIPQAICARHALCIGAKTIWITKFFMVVTGILSYPIGKLLDVILGKELGQVYSRAQLEMLVKEQQLIGSVVKDEALIIAGALTLTTKNVKDIMTPLSDVFMISVNSILDFDTMNEIVRNGFTRVPIYEGERSNIKAVLNVKDLAFIDPDDKIPVTTVCTFYNRSILIVPDNTILRTMLNDFRQGKAHMAFVERLETECDGDPYRVLIGLVTLEDVIEEIIQAEIMDETDVFTDNVKKQRRLVRNQDFSVFNIPETGKYPRLSPQLKVAALRHLASNVKYFCEDYITINVLQSLLNANILVEHTFKSDVDCSENVIFKKGKEANYAILILQGKAITEVSMESLLFEAGPFVLFGESLFK 631          
BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Match: SMESG000023862.1 (SMESG000023862.1)

HSP 1 Score: 337.421 bits (864), Expect = 6.792e-106
Identity = 254/596 (42.62%), Postives = 357/596 (59.90%), Query Frame = 1
Query:  157 LYGMTVHLDSVSFSENVVLIPARKPVNISLYGRNLSRVHSVSFTSTNASQFSLC--------DNLRNTQSFPVTMHNGLAHTSIILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKM-LPIWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLHLFIAAGSPQEKKYAKIIAPIRXXXXXXXXXXXXXXXXXXSTLTILVDDFTGNGLIAVIGSTLGIVILGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKELGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLDNAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLDPDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYRTNLD---QIIGLVTLXXXXXXXXXXXXXXXXXX-YNNEQRTRRSLNK-QDFSIFHESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVKYNPLNK-DANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGETILKS 1899
            L G T+ LD++S    ++ +     +N  L+G  + +      T  N +   LC        DN  NT+ +                        F  CL  E           W HQG +K   +K    + +P WL+I+ +I+ F  S  FSG+N+GLM+L  + L  F  AG+ +EKKYAK I PIR HGN LL T+L GNVL NS+LTI +     N ++ +  +T+GIVI GEI+PQ+  +R AL     T+ +T + +I++F +S+P+GK LD V+G+E+   YSREKL+ ++ +Q+ +G V KDE+ II GAL LT KT  D+MT + + FMI ++++L++  + +IVRNG+TRIPVY+ ++NNIK VLNIKDL  +DP DNIPV T+C+FY R I+ V     L E+L EFKKGK HLAF+ +     + D   ++IGLVTLEDVIEEIIQ EIIDETD+ YNN  R ++ +N+   F   H ++    L PQL    LQ++   I SF E  IS++VLKSLL++ IV    ++ L+K  +N II   +    AILLL G VSV+ S+E L F  GPF+ FGE ILKS
Sbjct:   10 LSGFTLRLDTISREGGIITVSNEDELNAVLFGTGIGKCSHAYLTQQNVNNKDLCYANVSKSTDNFENTRVW-----------------------IFLFCLLCEGQ---------WLHQGTEKTKTLKTNHNIYIPKWLLIVGVIVCFGFSSFFSGINMGLMTLQPSTLKFFKEAGNTKEKKYAKAIYPIRKHGNILLCTILFGNVLANSSLTIFMSHLIKNPVVTLFTATIGIVIFGEILPQAFGARNALTFSYYTINLTILCIILSFFLSYPLGKFLDWVMGEEINQPYSREKLKQIMIEQERLGLVYKDEMEIIAGALTLTEKTVADVMTPISHVFMISFNAILDYKTMKEIVRNGYTRIPVYDVDKNNIKGVLNIKDLLFIDPQDNIPVSTICTFYDRQILIVPHDVKLPEILNEFKKGKAHLAFIEKVINAEDGDPFQKLIGLVTLEDVIEEIIQDEIIDETDMFYNNVMREKKIMNRGATFENLHSTSNQQNLPPQLYEATLQYMAKSIHSFNEKFISYSVLKSLLHSKIVCN-HFHSLDKPSSNVIISMGEHTTKAILLLQGSVSVVTSSEGLIFVGGPFMMFGEGILKS 572          
The following BLAST results are available for this feature:
BLAST of Metal transporter cnnm2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CNNM44.252e-9541.48cyclin and CBS domain divalent metal cation transp... [more]
CNNM23.265e-9346.88cyclin and CBS domain divalent metal cation transp... [more]
CNNM26.424e-9346.88cyclin and CBS domain divalent metal cation transp... [more]
CNNM26.495e-7151.78cyclin and CBS domain divalent metal cation transp... [more]
CNNM13.007e-6640.87cyclin and CBS domain divalent metal cation transp... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cnnm-11.292e-6840.14Metal transporter cnnm-1 [Source:UniProtKB/Swiss-... [more]
cnnm-11.292e-6840.14Metal transporter cnnm-1 [Source:UniProtKB/Swiss-... [more]
cnnm-37.752e-5536.53Metal transporter cnnm-3 [Source:UniProtKB/Swiss-... [more]
cnnm-31.134e-5436.53Metal transporter cnnm-3 [Source:UniProtKB/Swiss-... [more]
cnnm-24.165e-5431.00Metal transporter cnnm-2 [Source:UniProtKB/Swiss-... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
uex5.382e-9841.25gene:FBgn0262124 transcript:FBtr0346683[more]
uex5.382e-9841.25gene:FBgn0262124 transcript:FBtr0302227[more]
uex5.382e-9841.25gene:FBgn0262124 transcript:FBtr0302226[more]
uex5.382e-9841.25gene:FBgn0262124 transcript:FBtr0334938[more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cnnm4b1.268e-10049.25cyclin and CBS domain divalent metal cation transp... [more]
cnnm2a4.919e-10042.17cyclin and CBS domain divalent metal cation transp... [more]
cnnm2b2.562e-9746.18cyclin and CBS domain divalent metal cation transp... [more]
cnnm4b1.511e-9048.88cyclin and CBS domain divalent metal cation transp... [more]
cnnm2b3.190e-7948.36cyclin and CBS domain divalent metal cation transp... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ihh5.023e-10145.71indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187... [more]
ihh7.300e-10145.62indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187... [more]
ihh9.131e-10145.62indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187... [more]
cnnm47.616e-9645.01cyclin and CBS domain divalent metal cation transp... [more]
ihh8.461e-9643.30indian hedgehog [Source:Xenbase;Acc:XB-GENE-484187... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cnnm23.121e-9346.88cyclin M2 [Source:MGI Symbol;Acc:MGI:2151054][more]
Cnnm25.768e-9346.88cyclin M2 [Source:MGI Symbol;Acc:MGI:2151054][more]
Cnnm43.245e-9240.68cyclin M4 [Source:MGI Symbol;Acc:MGI:2151060][more]
Cnnm11.206e-6641.14cyclin M1 [Source:MGI Symbol;Acc:MGI:1891366][more]
Cnnm11.337e-6641.14cyclin M1 [Source:MGI Symbol;Acc:MGI:1891366][more]
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BLAST of Metal transporter cnnm2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A0JPA0|CNNM4_XENTR3.340e-10045.71Metal transporter CNNM4 OS=Xenopus tropicalis OX=8... [more]
sp|Q6P4Q7|CNNM4_HUMAN2.042e-9441.48Metal transporter CNNM4 OS=Homo sapiens OX=9606 GN... [more]
sp|Q5U2P1|CNNM2_RAT1.043e-9246.67Metal transporter CNNM2 OS=Rattus norvegicus OX=10... [more]
sp|P0C588|CNNM4_RAT1.758e-9240.85Metal transporter CNNM4 OS=Rattus norvegicus OX=10... [more]
sp|Q9H8M5|CNNM2_HUMAN3.085e-9246.88Metal transporter CNNM2 OS=Homo sapiens OX=9606 GN... [more]
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BLAST of Metal transporter cnnm2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2LT865.013e-14648.47Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A419PQF54.610e-14547.82Metal transporter CNNM2 (Fragment) OS=Clonorchis s... [more]
A0A4S2LT541.408e-14348.47Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A3Q0KPE44.652e-14348.34Putative annexin OS=Schistosoma mansoni OX=6183 PE... [more]
A0A074ZCH31.538e-14247.66Uncharacterized protein OS=Opisthorchis viverrini ... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cnnm2a1.083e-10141.28cyclin and CBS domain divalent metal cation transp... [more]
cnnm2a1.886e-10141.28cyclin and CBS domain divalent metal cation transp... [more]
cnnm2b9.465e-9645.67metal transporter CNNM2-like [Source:NCBI gene;Acc... [more]
cnnm2b9.879e-9645.67metal transporter CNNM2-like [Source:NCBI gene;Acc... [more]
cnnm2b8.239e-9545.67metal transporter CNNM2-like [Source:NCBI gene;Acc... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cnnm4b1.713e-9042.42cyclin and CBS domain divalent metal cation transp... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
MAM31.527e-3435.56Protein required for normal mitochondrial morpholo... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO486941.163e-9544.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO309926.587e-3434.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Metal transporter cnnm2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cnnm4b6.631e-10350.00metal transporter CNNM4 [Source:NCBI gene;Acc:1053... [more]
cnnm4b1.466e-10250.00metal transporter CNNM4 [Source:NCBI gene;Acc:1053... [more]
cnnm4b2.219e-10250.00metal transporter CNNM4 [Source:NCBI gene;Acc:1053... [more]
cnnm2b8.668e-9745.79cyclin and CBS domain divalent metal cation transp... [more]
cnnm2b1.108e-9545.79cyclin and CBS domain divalent metal cation transp... [more]
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BLAST of Metal transporter cnnm2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000070597.10.000e+094.23SMESG000070597.1[more]
SMESG000070597.10.000e+094.55SMESG000070597.1[more]
SMESG000070597.10.000e+094.46SMESG000070597.1[more]
SMESG000047046.12.580e-15252.87SMESG000047046.1[more]
SMESG000023862.16.792e-10642.62SMESG000023862.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031752 ID=SMED30031752|Name=Metal transporter cnnm2|organism=Schmidtea mediterranea sexual|type=transcript|length=2118bp
TCCGATCTAAACTATTAGTTTTTTTAAATTATAGTTTTAGTATAAATTAA
ATTGCAATGAAATATTTATTTATTATATTTTGACATGAAACCTTTTTTGG
TGTTAATCATTATCTTAACAAAAATAATAAGTCCCTCAATGAACCATGAG
CCTCAATTGTATGGTATGACAGTGCACCTTGATTCAGTTAGTTTTTCTGA
AAATGTAGTATTGATTCCAGCAAGAAAACCTGTTAATATTAGTCTTTATG
GGCGCAATTTAAGTCGAGTTCATTCAGTTTCTTTTACATCTACGAATGCT
TCTCAATTCTCTTTGTGCGATAATCTGAGAAACACACAATCGTTTCCTGT
AACAATGCATAACGGTTTAGCTCACACTTCAATTATTTTGCGTCCATTTT
TCGACAAAGAGAAATTTTTTTACATCTGTCTTAGTCATGAAGTTAACGTT
ACAGACAACAGTACTGCAATGGTTTGGCGCCATCAAGGTTTTGATAAAGA
CGTAATTGTTAAAGTATTTGAAAAGATGCTTCCAATTTGGTTAATGATTA
TTCTAATTATATTATTATTTTCGTTATCTGGATTGTTCAGTGGCCTTAAT
CTCGGTCTCATGTCTTTATCGATCAATGATCTTCACTTATTTATTGCTGC
TGGTTCACCACAGGAAAAGAAATACGCAAAAATCATTGCTCCCATAAGAA
ATCATGGGAATTTTTTACTCGCTACACTTTTGTTGGGCAATGTTTTAGTA
AATAGCACTCTTACTATACTAGTAGATGATTTTACTGGAAATGGATTAAT
TGCAGTAATTGGTTCTACATTGGGCATTGTTATTTTGGGAGAAATAATTC
CTCAATCTGTCACTTCAAGATACGCTTTAGTTATTGGAGCGAAAACAATG
TGGATCACCAAAATTTTCATGATTATAACTTTTGTTGTATCCTTTCCTAT
CGGGAAAATGTTAGACAAAGTTCTAGGAAAAGAATTAGGTGTCGTTTACA
GCCGAGAGAAACTAGAAATACTCGTGAAGCAGCAGCAACTGATGGGGGCT
GTTGTCAAAGATGAAGTAAACATTATTACAGGAGCTTTGAATCTCACAAC
AAAAACAGCAAAAGACATAATGACAGATTTGGATAATGCGTTTATGATCC
CATATTCCTCAGTGTTGAATTTTGATCTGTTAAATCAAATAGTTCGAAAT
GGTTTTACCAGAATACCGGTTTACGAAGGAGAAAGAAATAATATTAAAGC
AGTTCTCAATATTAAGGATTTAACACTATTAGATCCCGACGACAATATTC
CAGTGTGCACTGTTTGCTCATTTTACAAAAGACCGATAATGTGTGTTTCT
TCACAAACTTTTCTTCGAGAAATGTTAGAAGAATTCAAAAAAGGAAAAAC
ACATTTGGCTTTTGTTACGGAAAAAAATTATAGGACAAATCTAGATCAAA
TTATAGGACTAGTGACACTAGAAGATGTTATTGAAGAAATTATTCAGGCG
GAGATCATTGACGAGACAGATATTTACAACAATGAACAGAGGACTAGGCG
CAGCTTGAACAAACAGGATTTCAGCATATTTCATGAGTCCAATCAAACTT
CCAAATTAGCGCCCCAATTGAAATTGACTGCCCTGCAACACTTGTATGCA
GAAATCAGCTCGTTCAGAGAAGACCTGATCAGCTTCAATGTTCTCAAAAG
TCTTCTGAATGCCAACATAGTAATCGAAGTCAAATACAATCCTTTGAATA
AAGATGCCAATACGATCATTCCAAAGGATAAAGTTCTGAATCATGCAATT
TTACTATTGCATGGTCGTGTTTCGGTTCTTGTTAGCAATGAAAATCTGTA
TTTCGAATCAGGACCATTTATATTTTTCGGAGAAACTATTCTAAAAAGTG
ATCTTTATACTTTATTACGCAAGTTATGCATGCATATTGTTTATTTATGT
ATATTTATATATCTTCAGCTAAAAGTAAGTGATCTAAAACTGTTTCAACT
ACAATTTTTCAAAACTTTTAAATGGGAATTTATACAGTGACTATCATAAA
AATATCATTTATTTTATAGAATTGATACTATAATATTTGTAAGAGTAAAT
ATTAAAAGTAAAATTTAT
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protein sequence of SMED30031752-orf-1

>SMED30031752-orf-1 ID=SMED30031752-orf-1|Name=SMED30031752-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=652bp
MKPFLVLIIILTKIISPSMNHEPQLYGMTVHLDSVSFSENVVLIPARKPV
NISLYGRNLSRVHSVSFTSTNASQFSLCDNLRNTQSFPVTMHNGLAHTSI
ILRPFFDKEKFFYICLSHEVNVTDNSTAMVWRHQGFDKDVIVKVFEKMLP
IWLMIILIILLFSLSGLFSGLNLGLMSLSINDLHLFIAAGSPQEKKYAKI
IAPIRNHGNFLLATLLLGNVLVNSTLTILVDDFTGNGLIAVIGSTLGIVI
LGEIIPQSVTSRYALVIGAKTMWITKIFMIITFVVSFPIGKMLDKVLGKE
LGVVYSREKLEILVKQQQLMGAVVKDEVNIITGALNLTTKTAKDIMTDLD
NAFMIPYSSVLNFDLLNQIVRNGFTRIPVYEGERNNIKAVLNIKDLTLLD
PDDNIPVCTVCSFYKRPIMCVSSQTFLREMLEEFKKGKTHLAFVTEKNYR
TNLDQIIGLVTLEDVIEEIIQAEIIDETDIYNNEQRTRRSLNKQDFSIFH
ESNQTSKLAPQLKLTALQHLYAEISSFREDLISFNVLKSLLNANIVIEVK
YNPLNKDANTIIPKDKVLNHAILLLHGRVSVLVSNENLYFESGPFIFFGE
TILKSDLYTLLRKLCMHIVYLCIFIYLQLKVSDLKLFQLQFFKTFKWEFI
Q*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR002550CNNM
IPR000644CBS_dom
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000644CBS domainPFAMPF00571CBScoord: 415..469
e-value: 8.6E-4
score: 19.7
IPR000644CBS domainPROSITEPS51371CBScoord: 414..477
score: 9.896
IPR000644CBS domainPROSITEPS51371CBScoord: 346..407
score: 7.706
NoneNo IPR availableGENE3DG3DSA:3.10.580.10coord: 325..477
e-value: 2.5E-50
score: 172.2
NoneNo IPR availablePANTHERPTHR12064:SF26METAL TRANSPORTER CNNM4coord: 122..606
NoneNo IPR availablePANTHERPTHR12064ANCIENT CONSERVED DOMAIN PROTEIN-RELATEDcoord: 122..606
NoneNo IPR availableCDDcd04590CBS_pair_CorC_HlyC_assoccoord: 341..465
e-value: 2.81433E-26
score: 101.804
NoneNo IPR availableSUPERFAMILYSSF54631CBS-domain paircoord: 330..470
NoneNo IPR availableTMHMMTMhelixcoord: 234..256
NoneNo IPR availableTMHMMTMhelixcoord: 263..285
NoneNo IPR availableTMHMMTMhelixcoord: 151..173
NoneNo IPR availableTMHMMTMhelixcoord: 208..230
IPR002550CNNM, transmembrane domainPFAMPF01595DUF21coord: 156..326
e-value: 9.4E-33
score: 113.4
IPR002550CNNM, transmembrane domainPROSITEPS51846CNNMcoord: 147..327
score: 45.093