carboxypeptidase E

Query:   86 LEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSCPNSD----FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            L+    I + +H   EL+  L  +  +C++I+ +Y      V ++     L VI    +P  H PG PEFKY+GNMHGNE VGRELL+FLA YLC+++  GNE + N++ STRIHI+PS+NPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N + G   +HLL   KK +D++ +L  ET  VI WI  IPFVLSAN+HGGD+VANYPYD++     ++ S +PD+ +F+ LA +YS +NP M    +  C  +D    F+  DG TNG  WYS+ GGMQDFNYL++NCFEIT+E+ C KFP  + L  +W  N  SL+++++  H G+KG V  R   G  P+A A I          VE I H VT+A +GDY+RLL+PG Y + A+APG+ +  + V V       A  ++F LE
Sbjct:   43 LQQEDGISFEYHRYPELREALVSVWLQCTAISRIY-----TVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFV--DGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFV--RDLQG-NPIANATI---------SVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYS---PAAGVDFELE 450          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSEL-GRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEP 1345
            I + HH+  ++  +L R   +C+ +   Y      + ++     L VI F   P +H    PE K +GN+HGNEV GRE+L++LA YLC +++ GN  ++ ++ +TRIH+LPSMNPDG+++A       N W  GR NA N+DLNRNFPDL    ++ +E  G + DH+   +     ++  ET  ++ W+ +IPFVLSA++HGGD+V +YP+D S    + +  S TPD ++FK L+ +Y+  +P M  R ++    +FL +  I NGA WYS +GGM DFNYL TNCFEIT+E+GC KFP  + LY  W  N +SL+NF++  H GIKG+V   ++   KPV  A I +           I H +TTA +GDY+RLL PG + VIA APG+   I+ V++    + + +V +F L+P
Sbjct:   46 IRFSHHSYAQMVRVLRRTASRCAHVARTY-----SIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYILWQHNKESLLNFVETVHRGIKGVV---TDKFGKPVKNARISVKG---------IRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRV-DFILQP 446          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKS---TVDG--KNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQ 1357
            + +RHH   +L   L ++ ++C  IT +Y      + ++V    LYV+ F   P  H P  PE KYVGNMHGNE +GREL+L L+++LC++    N+ +  +++ TRIHILPSMNPDG+++A      +  ++VGR NAN VDLNRNFPDL+  ++ N + G    HL       + ++E ET  VI W+ S  FVLSAN+HGG VVANYPYDKS    V G  +  ++ TPD+++F+ LA  YS  +  MF+  +     D+ P DGITNGA WYSLS GMQDFNYL TNCFEITLE+ C KFP  + L   W+ N ++L+ F++  H GIKG+VL   +  Y  +A AVI ++ +          H VT+   GDY+RLL+PG Y+V A APG+  +   V V         ++NF L+ +  Q
Sbjct:   21 VTFRHHRYDDLVRTLYKVQNECPGITRVY-----SIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNW-KSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGWNC---GDYFP-DGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVL---DENYNNLANAVISVSGIN---------HDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV---GPAEPTLVNFHLKRSIPQ 421          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSEL-GRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEP 1345
            I + HH+  ++  +L R   +C+ +   Y      + ++     L VI F   P +H    PE K +GN+HGNEV GRE+L++LA YLC +++ GN  ++ ++ +TRIH+LPSMNPDG+++A       N W  GR NA N+DLNRNFPDL    ++ +E  G + DH+   +     ++  ET  ++ W+ +IPFVLSA++HGGD+V +YP+D S    + +  S TPD ++FK L+ +Y+  +P M  R ++    +FL +  I NGA WYS +GGM DFNYL TNCFEIT+E+GC KFP  + LY  W  N +SL+NF++  H GIKG+V   ++   KPV  A I +           I H +TTA +GDY+RLL PG + VIA APG+   I+ V++    + + +V +F L+P
Sbjct:  172 IRFSHHSYAQMVRVLRRTASRCAHVARTY-----SIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYILWQHNKESLLNFVETVHRGIKGVV---TDKFGKPVKNARISVKG---------IRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRV-DFILQP 572          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSEL-GRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEP 1345
            I + HH+  ++  +L R   +C+ +   Y      + ++     L VI F   P +H    PE K +GN+HGNEV GRE+L++LA YLC +++ GN  ++ ++ +TRIH+LPSMNPDG+++A       N W  GR NA N+DLNRNFPDL    ++ +E  G + DH+   +     ++  ET  ++ W+ +IPFVLSA++HGGD+V +YP+D S    + +  S TPD ++FK L+ +Y+  +P M  R ++    +FL +  I NGA WYS +GGM DFNYL TNCFEIT+E+GC KFP  + LY  W  N +SL+NF++  H GIKG+V   ++   KPV  A I +           I H +TTA +GDY+RLL PG + VIA APG+   I+ V++    + + +V +F L+P
Sbjct:  183 IRFSHHSYAQMVRVLRRTASRCAHVARTY-----SIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYILWQHNKESLLNFVETVHRGIKGVV---TDKFGKPVKNARISVKG---------IRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRV-DFILQP 583          

Query:  107 EYRH-HNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRT---RNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELG-RKQDHLLNKKTIDEDELER--ETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA---SLTPDNEVFKFLALSYSKYNPRMFKRK----DSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPA---DSQNEVKTNNPLCNEIA 1399
            E+ H HN  +L+  L  IN+KC  IT LY     ++ ++V    L VI F  +P  HIP  PE K +GNMHGNE +GRELLL  A+ LC+  +  ++ +  ++ ST IHILPSMNPDG+++A  T   + +W+ GR+N N VDLNR+FPDLD + ++  ++G  K DHLL   ++ ED ++R  ET+ V  W  S+PFVLSAN H GD+VANYP+D + +D  +Q    S +PD+  F++LA SY+  +  M K      D      F  + GITNGAKWYS++GGMQDFNYLATN  EITLE+ C K P+G  L  FW  N KS+  ++  +H G+KG+V+       +P+ +AV+ I N T   +  P+ H VTT SEGD+YR+L  G+Y +I AA G+    + V V N+ + SA V+NF L PA    S+NE +    L NEIA
Sbjct:   36 EWGHYHNQAQLEAKLGEINEKCPEITTLY-----EIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFYELQKIGVPKFDHLL---SLFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFD-AAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTG--EPIKRAVVWIRNGT---ETVPVKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFALSPAADEPSENEQEQIAELVNEIA 469          

Query:  107 EYRH-HNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRT---RNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELG-RKQDHLLNKKTIDEDELER--ETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA---SLTPDNEVFKFLALSYSKYNPRMFKRK----DSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPA---DSQNEVKTNNPLCNEIA 1399
            E+ H HN  +L+  L  IN+KC  IT LY     ++ ++V    L VI F  +P  HIP  PE K +GNMHGNE +GRELLL  A+ LC+  +  ++ +  ++ ST IHILPSMNPDG+++A  T   + +W+ GR+N N VDLNR+FPDLD + ++  ++G  K DHLL   ++ ED ++R  ET+ V  W  S+PFVLSAN H GD+VANYP+D + +D  +Q    S +PD+  F++LA SY+  +  M K      D      F  + GITNGAKWYS++GGMQDFNYLATN  EITLE+ C K P+G  L  FW  N KS+  ++  +H G+KG+V+       +P+ +AV+ I N T   +  P+ H VTT SEGD+YR+L  G+Y +I AA G+    + V V N+ + SA V+NF L PA    S+NE +    L NEIA
Sbjct:   36 EWGHYHNQAQLEAKLGEINEKCPEITTLY-----EIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFYELQKIGVPKFDHLL---SLFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFD-AAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTG--EPIKRAVVWIRNGT---ETVPVKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFALSPAADEPSENEQEQIAELVNEIA 469          

Query:  107 EYRH-HNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRT---RNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELG-RKQDHLLNKKTIDEDELER--ETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA---SLTPDNEVFKFLALSYSKYNPRMFKRK----DSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPA---DSQNEVKTNNPLCNEIA 1399
            E+ H HN  +L+  L  IN+KC  IT LY     ++ ++V    L VI F  +P  HIP  PE K +GNMHGNE +GRELLL  A+ LC+  +  ++ +  ++ ST IHILPSMNPDG+++A  T   + +W+ GR+N N VDLNR+FPDLD + ++  ++G  K DHLL   ++ ED ++R  ET+ V  W  S+PFVLSAN H GD+VANYP+D + +D  +Q    S +PD+  F++LA SY+  +  M K      D      F  + GITNGAKWYS++GGMQDFNYLATN  EITLE+ C K P+G  L  FW  N KS+  ++  +H G+KG+V+       +P+ +AV+ I N T   +  P+ H VTT SEGD+YR+L  G+Y +I AA G+    + V V N+ + SA V+NF L PA    S+NE +    L NEIA
Sbjct:   36 EWGHYHNQAQLEAKLGEINEKCPEITTLY-----EIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFYELQKIGVPKFDHLL---SLFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFD-AAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTG--EPIKRAVVWIRNGT---ETVPVKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFALSPAADEPSENEQEQIAELVNEIA 469          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDK-STVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDF----LPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQ 1309
            + + H N   L + +  ++ K  ++TH+Y        ++V    L+V+   + P  H   IPEFKYV NMHGNEV GR  L+ LA  L + +   N W+R +V+STRIH++PSMNPDG++ A+      V GR NAN  DLNRNFP      F  SE+                  + ET+ ++ W   IPF LSAN+HGG  + NYP+D   T   ++  + +PDN +F  LA +Y++ + RM+K+   C + D      P++GI NGA WY +SGGMQD+NYL TNCFE+T+E+ C KFP  K L   W  N  +L+ FI   H  I G+V+  +++G + +  A + I               V +  EG+++RL   G+Y +      +    Q V VT + +
Sbjct:   54 LNFSHMNYSTLTDHIHNLHRKFPNLTHIY-----SAGQSVQGRELWVLVVSRYPIEHRKLIPEFKYVANMHGNEVTGRVFLVSLAHTLLENY-NSNLWIRQLVDSTRIHLMPSMNPDGYEHASEGDQAGVTGRQNANGKDLNRNFPSRFPNYFPTSEI------------------QPETIAIMNWTRQIPFALSANLHGGTTLVNYPFDDFPTRTRQSHYAPSPDNALFVRLAYTYARGHERMWKKGPRCLDDDLNISVDPQNGIINGADWYIVSGGMQDWNYLNTNCFEVTVEMNCEKFPQTKKLRYLWEENKYALLKFIDLIHGAIHGLVID-ADTG-EGIVNATVSIDERAKI---------VVSYGEGEFWRLANMGKYDLTFDHSDYYPVTQTVHVTPQDR 425          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDK-STVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDF----LPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQ 1309
            + + H N   L + +  ++ K  ++TH+Y        ++V    L+V+   + P  H   IPEFKYV NMHGNEV GR  L+ LA  L + +   N W+R +V+STRIH++PSMNPDG++ A+      V GR NAN  DLNRNFP      F  SE+                  + ET+ ++ W   IPF LSAN+HGG  + NYP+D   T   ++  + +PDN +F  LA +Y++ + RM+K+   C + D      P++GI NGA WY +SGGMQD+NYL TNCFE+T+E+ C KFP  K L   W  N  +L+ FI   H  I G+V+  +++G + +  A + I               V +  EG+++RL   G+Y +      +    Q V VT + +
Sbjct:   54 LNFSHMNYSTLTDHIHNLHRKFPNLTHIY-----SAGQSVQGRELWVLVVSRYPIEHRKLIPEFKYVANMHGNEVTGRVFLVSLAHTLLENY-NSNLWIRQLVDSTRIHLMPSMNPDGYEHASEGDQAGVTGRQNANGKDLNRNFPSRFPNYFPTSEI------------------QPETIAIMNWTRQIPFALSANLHGGTTLVNYPFDDFPTRTRQSHYAPSPDNALFVRLAYTYARGHERMWKKGPRCLDDDLNISVDPQNGIINGADWYIVSGGMQDWNYLNTNCFEVTVEMNCEKFPQTKKLRYLWEENKYALLKFIDLIHGAIHGLVID-ADTG-EGIVNATVSIDERAKI---------VVSYGEGEFWRLANMGKYDLTFDHSDYYPVTQTVHVTPQDR 425          

Query:  287 PEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWV---VGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN-QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFK-SQIQCVLVTNESQFSAKVLNFRLEPADS 1354
            P  KY+ NMHG+E VGR+LL+++A YL   H   ++ +  +V ST I+++P+MNPDG+ ++     E +   VGR NA N+DLNR+FPD          L +   H L  ++      + ET  ++ WI S PFVLSAN HGG VVA+YPYD S    +  + SLTPD+ VFK LA +YS  +P M  RK +  N  F    GITNGA WY LSGGMQDFNY  +NCFE+T+E+ C K+P    L   W  N  SL+  ++  HIGIKG+V     SG+ P+A A     NV  AG  E  +    T+  G+Y+RLL PG YSV A+A G++ S  Q V VTN++Q  A  L+F+L P ++
Sbjct:   92 PPVKYIANMHGDETVGRQLLVYMAQYLLGNHERISD-LGQLVNSTDIYLVPTMNPDGYALSQEGNCESLPNYVGRGNAANIDLNRDFPD---------RLEQSHVHQLRAQS-----RQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIM--RKGNNCNDSF--SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLV--TDASGF-PIADA-----NVYVAGLEEKPMR---TSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQ-EALRLDFKLAPVET 421          

Query:  287 PEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWV---VGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN-QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFK-SQIQCVLVTNESQFSAKVLNFRLEPADS 1354
            P  KY+ NMHG+E VGR+LL+++A YL   H   ++ +  +V ST I+++P+MNPDG+ ++     E +   VGR NA N+DLNR+FPD          L +   H L  ++      + ET  ++ WI S PFVLSAN HGG VVA+YPYD S    +  + SLTPD+ VFK LA +YS  +P M  RK +  N  F    GITNGA WY LSGGMQDFNY  +NCFE+T+E+ C K+P    L   W  N  SL+  ++  HIGIKG+V     SG+ P+A A     NV  AG  E  +    T+  G+Y+RLL PG YSV A+A G++ S  Q V VTN++Q  A  L+F+L P ++
Sbjct:   92 PPVKYIANMHGDETVGRQLLVYMAQYLLGNHERISD-LGQLVNSTDIYLVPTMNPDGYALSQEGNCESLPNYVGRGNAANIDLNRDFPD---------RLEQSHVHQLRAQS-----RQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIM--RKGNNCNDSF--SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLV--TDASGF-PIADA-----NVYVAGLEEKPMR---TSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQ-EALRLDFKLAPVET 421          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYD--------------KSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNN 1378
            +Y HHN   +++ L  I+    S+T LY      + K+V    L+V+    +P  H+PG+PEFKYV NMHGNEVVG+ELLL L  Y+ +++   ++ +  +V  TR+H L SMNPDG++I+        VGR NA+ +DLNRNFPD         + G  +    NK T      E E   V+ W  S+PFVLSAN+HGG +VANYP+D               S+++G+ + + T DN +FK LA  YS  +P M+  +  C    ++F P DGITNGA+WYS++GGMQD+NY+   C E+T+E+GC KFP    L  +W  + + L+ FI+  H GI G V   S  G  P+A AV+++             H   +   GDY++L +PGR+++      +      V V +   F  + ++  L P D Q+    N+
Sbjct:  306 KYEHHNFTAMESYLRAISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTGGVGRANAHGIDLNRNFPD---------QYGTDR---FNKVT------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGR-KPNPTEDNALFKHLAGIYSNAHPTMYLGQ-PCELFQNEFFP-DGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFV--HSTIG-TPIAGAVVRLDGAN---------HSTYSQVFGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMR-MDITLMPDDPQHWASAND 705          

Query:  494 VGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN-QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFK-SQIQCVLVTNESQFSAKVLNFRLEPADS 1354
            VGR NA N+DLNR+FPD          L +   H L  ++      + ET  ++ WI S PFVLSAN HGG VVA+YPYD S    +  + SLTPD+ VFK LA +YS  +P M  RK +  N  F    GITNGA WY LSGGMQDFNY  +NCFE+T+E+ C K+P    L   W  N  SL+  ++  HIGIKG+V     SG+ P+A A     NV  AG  E  +    T+  G+Y+RLL PG YSV A+A G++ S  Q V VTN++Q  A  L+F+L P ++
Sbjct:   16 VGRGNAANIDLNRDFPD---------RLEQSHVHQLRAQS-----RQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIM--RKGNNCNDSF--SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVT--DASGF-PIADA-----NVYVAGLEEKPMR---TSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQ-EALRLDFKLAPVET 274          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYD--------------KSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNN 1378
            +Y HHN   +++ L  I+    S+T LY      + K+V    L+V+    +P  H+PG+PEFKYV NMHGNEVVG+ELLL L  Y+ +++   ++ +  +V  TR+H L SMNPDG++I+        VGR NA+ +DLNRNFPD         + G  +    NK T      E E   V+ W  S+PFVLSAN+HGG +VANYP+D               S+++G+ + + T DN +FK LA  YS  +P M+  +  C    ++F P DGITNGA+WYS++GGMQD+NY+   C E+T+E+GC KFP    L  +W  + + L+ FI+  H GI G V   S  G  P+A AV+++             H   +   GDY++L +PGR+++      +      V V +   F  + ++  L P D Q+    N+
Sbjct:  453 KYEHHNFTAMESYLRAISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTGGVGRANAHGIDLNRNFPD---------QYGTDR---FNKVT------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGR-KPNPTEDNALFKHLAGIYSNAHPTMYLGQ-PCELFQNEFFP-DGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFV--HSTIG-TPIAGAVVRLDGAN---------HSTYSQVFGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMR-MDITLMPDDPQHWASAND 852          

Query:  287 PEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWV---VGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN-QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFK-SQIQCVLVTNESQFSAKVLNFRLEPADS 1354
            P  KY+ NMHG+E VGR+LL+++A YL   H   ++ +  +V ST I+++P+MNPDG+ ++     E +   VGR NA N+DLNR+FPD          L +   H L  ++      + ET  ++ WI S PFVLSAN HGG VVA+YPYD S    +  + SLTPD+ VFK LA +YS  +P M  RK +  N  F    GITNGA WY LSGGMQDFNY  +NCFE+T+E+ C K+P    L   W  N  SL+  ++  HIGIKG+V     SG+ P+A A     NV  AG  E  +    T+  G+Y+RLL PG YSV A+A G++ S  Q V VTN++Q  A  L+F+L P ++
Sbjct:   92 PPVKYIANMHGDETVGRQLLVYMAQYLLGNHERISD-LGQLVNSTDIYLVPTMNPDGYALSQEGNCESLPNYVGRGNAANIDLNRDFPD---------RLEQSHVHQLRAQS-----RQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIM--RKGNNCNDSF--SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVT--DASGF-PIADA-----NVYVAGLEEKPMR---TSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQ-EALRLDFKLAPVET 421          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYD--------------KSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNN 1378
            +Y HHN   +++ L  I+    S+T LY      + K+V    L+V+    +P  H+PG+PEFKYV NMHGNEVVG+ELLL L  Y+ +++   ++ +  +V  TR+H L SMNPDG++I+        VGR NA+ +DLNRNFPD         + G  +    NK T      E E   V+ W  S+PFVLSAN+HGG +VANYP+D               S+++G+ + + T DN +FK LA  YS  +P M+  +  C    ++F P DGITNGA+WYS++GGMQD+NY+   C E+T+E+GC KFP    L  +W  + + L+ FI+  H GI G V   S  G  P+A AV+++             H   +   GDY++L +PGR+++      +      V V +   F  + ++  L P D Q+    N+
Sbjct:  453 KYEHHNFTAMESYLRAISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTGGVGRANAHGIDLNRNFPD---------QYGTDR---FNKVT------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGR-KPNPTEDNALFKHLAGIYSNAHPTMYLGQ-PCELFQNEFFP-DGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFV--HSTIG-TPIAGAVVRLDGAN---------HSTYSQVFGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMR-MDITLMPDDPQHWASAND 852          

Query:  287 PEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWV---VGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN-QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFK-SQIQCVLVTNESQFSAKVLNFRLEPADS 1354
            P  KY+ NMHG+E VGR+LL+++A YL   H   ++ +  +V ST I+++P+MNPDG+ ++     E +   VGR NA N+DLNR+FPD          L +   H L  ++      + ET  ++ WI S PFVLSAN HGG VVA+YPYD S    +  + SLTPD+ VFK LA +YS  +P M  RK +  N  F    GITNGA WY LSGGMQDFNY  +NCFE+T+E+ C K+P    L   W  N  SL+  ++  HIGIKG+V     SG+ P+A A     NV  AG  E  +    T+  G+Y+RLL PG YSV A+A G++ S  Q V VTN++Q  A  L+F+L P ++
Sbjct:   92 PPVKYIANMHGDETVGRQLLVYMAQYLLGNHERISD-LGQLVNSTDIYLVPTMNPDGYALSQEGNCESLPNYVGRGNAANIDLNRDFPD---------RLEQSHVHQLRAQS-----RQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIM--RKGNNCNDSF--SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVT--DASGF-PIADA-----NVYVAGLEEKPMR---TSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQ-EALRLDFKLAPVET 421          

Query:   59 LCLIFVFLVL----EASGK--IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV 1294
             C   + L L    EA G+  I + +H   E++  L  +  +C SIT +Y      V ++     L V+    +P  H PG PEFKY+GNMHGNE VGRELL++LA YLC+++  GN+ + +++ STRIHI+PSMNPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N   G   +HLL   KK +DE+ +L  ET  VI WI  IPFVLSAN+HGGDVVANYPYD++     ++ S +PD+ VFK LA +YS YNP M    +  C   + D   K+GITNG  WYS+ GGMQDFNYL++NCFEITLE+ C KFP    L  +W  N  SL+N+I+  H G+ G V  R   G  P++ A +          VE I H +TTA +GDY+RLL PG Y V A+APG+ + ++ V V
Sbjct:    6 FCGAVLMLALSSVKEAEGENGISFEYHRYEEMRKSLVSVWLQCPSITRIY-----TVGESFEGRELLVLEMSDNPGIHEPGEPEFKYIGNMHGNEAVGRELLIYLAQYLCNEYQEGNDTIIDLIHSTRIHIMPSMNPDGFEKAASQPGEMKDWFVGRSNAQGIDLNRNFPDLDRIVYMNEREGGANNHLLKNMKKAVDENTKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRSGSTHEYSASPDDLVFKSLAKAYSIYNPVMSDTNRPPCRKNDDDSSFKEGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPPEDSLKQYWDQNRNSLVNYIEQVHRGVSGFV--RDLQG-NPISNASV---------SVEGIDHDITTAKDGDYWRLLAPGNYKVSASAPGYLTVVKKVAV 415          

Query:   59 LCLIFVFLVL----EASGK--IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV 1294
             C   + L L    EA G+  I + +H   E++  L  +  +C SIT +Y      V ++     L V+    +P  H PG PEFKY+GNMHGNE VGRELL++LA YLC+++  GN+ + +++ STRIHI+PSMNPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N   G   +HLL   KK +DE+ +L  ET  VI WI  IPFVLSAN+HGGDVVANYPYD++     ++ S +PD+ VFK LA +YS YNP M    +  C   + D   K+GITNG  WYS+ GGMQDFNYL++NCFEITLE+ C KFP    L  +W  N  SL+N+I+  H G+ G V  R   G  P++ A +          VE I H +TTA +GDY+RLL PG Y V A+APG+ + ++ V V
Sbjct:    6 FCGAVLMLALSSVKEAEGENGISFEYHRYEEMRKSLVSVWLQCPSITRIY-----TVGESFEGRELLVLEMSDNPGIHEPGEPEFKYIGNMHGNEAVGRELLIYLAQYLCNEYQEGNDTIIDLIHSTRIHIMPSMNPDGFEKAASQPGEMKDWFVGRSNAQGIDLNRNFPDLDRIVYMNEREGGANNHLLKNMKKAVDENTKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRSGSTHEYSASPDDLVFKSLAKAYSIYNPVMSDTNRPPCRKNDDDSSFKEGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPPEDSLKQYWDQNRNSLVNYIEQVHRGVSGFV--RDLQG-NPISNASV---------SVEGIDHDITTAKDGDYWRLLAPGNYKVSASAPGYLTVVKKVAV 415          

Query:   74 VFLVLEAS--GKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTR---NEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKS---TVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV 1294
            + L LEAS  G  +++HH   E+   L  +  +C  IT +Y      + ++     LYV+ F  +P  H    PEFKYVGNMHGNEV+GRELL++L+ +LC+++ AGNE +  ++  TRIHILPSMNPDG+++A R     N ++VGR N+  VDLNRNFPDL+ +++   E    Q+H L      E ++E ETL VI W+ +  FVLSAN+HGG VVANYP+DKS    + GK   S T D+++F+ LA +YS  +  M K  +     D+   +GITNGA WYSLS GMQDFNYL TNCFEITLE+ C KFP    L + W+ N ++L+++++  H GIKG+V   + +    ++ AVI +  ++         H +T+ + GDY+RLL+PG Y+V A+APG++     V V
Sbjct:   13 LLLGLEASLTGASDFQHHGYEEMVRALFAVQSECPYITRIY-----SIGRSTEGRHLYVLEFSDNPGIHETLEPEFKYVGNMHGNEVLGRELLIYLSQFLCEEYRAGNERITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNSKEVDLNRNFPDLNALMYY-YEKHNGQNHHLPLPDNWELQVEPETLAVIKWMQNYNFVLSANLHGGAVVANYPFDKSREPRIRGKTTYSATTDDKIFRKLAKTYSYAHSWMHKGWNC---GDYF-DEGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPATALANEWLANREALVSYMEQVHHGIKGMVYDENNNA---ISNAVISVAGIS---------HDITSGTLGDYFRLLLPGTYTVTASAPGYQPSTSTVTV 405          

Query:   74 VFLVLEAS--GKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTR---NEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKS---TVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV 1294
            + L LEAS  G  +++HH   E+   L  +  +C  IT +Y      + ++     LYV+ F  +P  H    PEFKYVGNMHGNEV+GRELL++L+ +LC+++ AGNE +  ++  TRIHILPSMNPDG+++A R     N ++VGR N+  VDLNRNFPDL+ +++   E    Q+H L      E ++E ETL VI W+ +  FVLSAN+HGG VVANYP+DKS    + GK   S T D+++F+ LA +YS  +  M K  +     D+   +GITNGA WYSLS GMQDFNYL TNCFEITLE+ C KFP    L + W+ N ++L+++++  H GIKG+V   + +    ++ AVI +  ++         H +T+ + GDY+RLL+PG Y+V A+APG++     V V
Sbjct:  145 LLLGLEASLTGASDFQHHGYEEMVRALFAVQSECPYITRIY-----SIGRSTEGRHLYVLEFSDNPGIHETLEPEFKYVGNMHGNEVLGRELLIYLSQFLCEEYRAGNERITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNSKEVDLNRNFPDLNALMYY-YEKHNGQNHHLPLPDNWELQVEPETLAVIKWMQNYNFVLSANLHGGAVVANYPFDKSREPRIRGKTTYSATTDDKIFRKLAKTYSYAHSWMHKGWNC---GDYF-DEGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPATALANEWLANREALVSYMEQVHHGIKGMVYDENNNA---ISNAVISVAGIS---------HDITSGTLGDYFRLLLPGTYTVTASAPGYQPSTSTVTV 537          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGR-KQDHLLNKKTIDEDEL-ERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQ 1276
            I++ +H+N ++ +IL++   KCS I+  Y      + ++V    L VI F  +P +H    PE K +GNMHGNEV+GR+LL++LA YLC +++ GNE ++ I+ +TRIHIL SMNPDG++IA    +E   W  GR NA N+DLNRNFPDL  + +        + DH+    +   +++   ET  ++ WI + PFV+SA++HGG++V +YP+D S    +++  S TPD ++F+ LA +Y+  +  M         + F  K GITNGA WYS +GGM DFNYL +NC+EIT+E+GC KFP  + LY  W  N ++L++F+++ H GIKGIV     +G K    A+I          V+ + H +TTA +GDY+RL+ PG + V A+A G+  Q
Sbjct:  186 IQFTYHSNSQMFSILKKTASKCSHISQTY-----SIGRSVEGKDLLVIEFSNNPGQHDLLEPEIKLIGNMHGNEVLGRQLLIYLAQYLCSEYLLGNERIQTIINTTRIHILASMNPDGYEIAASEGHEYNGWTSGRANAQNLDLNRNFPDLTSIFYNRRRFRHFRSDHIPIPDSYWMNKVVAPETYAIMKWIRTYPFVISASLHGGELVISYPFDFSRHPQEDRMYSPTPDEQIFRQLARTYADAHATMSNNDTERCGASFANKGGITNGALWYSFAGGMSDFNYLHSNCYEITVELGCDKFPSEEELYPEWRRNKEALLSFMESVHKGIKGIVKDEHGNGIK---GAIIS---------VKGLRHDITTAEDGDYWRLMNPGVHIVTASASGYSKQ 565          

Query:   98 GKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRN---EWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFK-RKDSCPNSD----FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV 1294
            G I Y +H   E+++ L  +  +C SI+ +Y      V ++     L VI    +P  H PG PEFKYVGNMHGNE VGRELLL+ A YLC+++   NE + N++ +TRIHI+PS+NPDG++ A +      +W VGR+NA  +DLNRNFPDLD++V+ N   G   +HLL   KK++DE+ +L  ET+ VI WI  IPFVLSAN+HGGD+VANYPYDK+     ++ S  PD+ +F+ LA SYS  NP M    +  C  SD    F+  DG TNGA WYS+ GGMQDFNYL++NCFEIT+E+GC KFP  + L  +W  N  SL+N++   H G+ G V  +   G+ P+A A I          V+ I H VT+A +GDY+RLL PG Y + A+APG+ +  + V V
Sbjct:   38 GDISYEYHRYPEMRDALVAVWLQCPSISRIY-----TVGRSFEGRELLVIEISDNPGEHEPGEPEFKYVGNMHGNEAVGRELLLYFAQYLCNEYQRENETIVNLIHNTRIHIMPSLNPDGFEKAAQQPGDIKDWFVGRSNAQGIDLNRNFPDLDRIVYLNEREGGTNNHLLQNLKKSVDENAKLAPETVAVIHWIMDIPFVLSANLHGGDLVANYPYDKTRSGSTHEYSACPDDGIFQSLARSYSSLNPTMSDPDRKPCRKSDDDSSFI--DGTTNGAAWYSVPGGMQDFNYLSSNCFEITVELGCDKFPPEEMLKSYWEENKDSLVNYLMQVHRGVTGFV--KDHHGF-PIANATI---------SVDGIDHDVTSAKDGDYWRLLAPGNYKITASAPGYLAVAKKVAV 428          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRT---RNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQ-DHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNNPLCNEI 1396
            I++ HH+  ++  +L++   +CS I+  Y      + ++     L  I F   P +H    PEF+Y+GNMHGNEV GRELL++LA +LC +++ GN  ++ ++ +TRIH+LPSMNPDG++ A       N W  GR NA N+DLNRNFPDL   V K   +   + DH+   ++  + ++  E   V+ W+ SIPFV+S ++HGGD+V +YPYD S    + +  S TPD +VF+ L  +Y   +P M  +  S    +F  K GI NGA+WYS SGGM DF+YL TNCFE+TLE+GC KFP    LY  W  N +++++ I+  H GIKG V  + E G  P+ KA I          V+ I H +TT  +GDY+RLL+PG Y V A A G+ S++   +        A  ++F L+  D +N      P+ NE+
Sbjct:   25 IQFIHHSYSDMVRVLKKTAARCSQISKTY-----SIGRSYEGKDLLAIEFSAQPGQHKALTPEFRYIGNMHGNEVAGRELLIYLAQFLCSEYLLGNSRIQTLINTTRIHLLPSMNPDGYEHAAEEGAGYNGWTNGRLNAQNIDLNRNFPDLTSEVHKIIRMPMARLDHMPIPESYWDGKIAPEAKAVMKWMRSIPFVISGSLHGGDLVVSYPYDFSRHPLEEKMFSPTPDEKVFQMLVKTYVAAHPIMSDKSTSRCGGNFNNKGGIINGAEWYSFSGGMADFSYLHTNCFELTLELGCEKFPTEDELYSIWQNNKEAMLSLIEMVHRGIKGFV--KDEHG-NPIKKARI---------SVKGIRHDITTGEDGDYFRLLIPGSYIVSAEAFGY-SKVTKKITLPAKMLKAGRVDFALQRVDVKNL-----PIGNEL 437          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRT---RNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQ-DHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVL 1327
            I++ HH+  ++  +L++   +CS I+  Y      + ++     L  I F   P +H    PEF+Y+GNMHGNEV GRELL++LA +LC +++ GN  ++ ++ +TRIH+LPSMNPDG++ A       N W  GR NA N+DLNRNFPDL   V K   +   + DH+   ++  + ++  E   V+ W+ SIPFV+S ++HGGD+V +YPYD S    + +  S TPD +VF+ L  +Y   +P M  +  S    +F  K GI NGA+WYS SGGM DF+YL TNCFE+TLE+GC KFP    LY  W  N +++++ I+  H GIKG V  + E G  P+ KA I          V+ I H +TT  +GDY+RLL+PG Y V A A G+        VT +    AK+L
Sbjct:   25 IQFIHHSYSDMVRVLKKTAARCSQISKTY-----SIGRSYEGKDLLAIEFSAQPGQHKALTPEFRYIGNMHGNEVAGRELLIYLAQFLCSEYLLGNSRIQTLINTTRIHLLPSMNPDGYEHAAEEGAGYNGWTNGRLNAQNIDLNRNFPDLTSEVHKIIRMPMARLDHMPIPESYWDGKIAPEAKAVMKWMRSIPFVISGSLHGGDLVVSYPYDFSRHPLEEKMFSPTPDEKVFQMLVKTYVAAHPIMSDKSTSRCGGNFNNKGGIINGAEWYSFSGGMADFSYLHTNCFELTLELGCEKFPTEDELYSIWQNNKEAMLSLIEMVHRGIKGFV--KDEHG-NPIKKARI---------SVKGIRHDITTGEDGDYFRLLIPGSYIVSAEAFGYSK------VTKKITLPAKML 414          

Query:   74 VFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHL-LNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKST---VDG--KNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGF 1267
            +FL+ E +  + + HH   +L   L  + ++C  IT +Y      + ++V    LYVI F  +P  H    PEFKYVGNMHGNEV+GRELL+ LA++LC+++   NE V  ++++TRIHILPSMNPDG+++A       N ++ GR N   VDLNRNFPDL+ V++ N + G    HL L    +   ++E ET  +I W+ +  FVLSAN+HGG VVANYPYDKS    + G  ++  S TPD+ +FK LA +YS  +  M     +  N D    +GITNGA WYSL  GMQDFNYL TNCFEITLE+ C KFP  + L   W  N ++L+ +I   H GIKG++   + +G   +A AVI I+          I H VT+   GDY+RLL+PG Y V A+A G+
Sbjct:   11 LFLLCEVAASLSFFHHRYDDLVRALYNVQNQCPYITRVY-----SIGRSVQGRHLYVIEFSDNPGIHELLEPEFKYVGNMHGNEVLGRELLIQLAEFLCEEYRNNNERVTRLIQTTRIHILPSMNPDGYEVAADQGPEGNGYLTGRYNYRQVDLNRNFPDLNTVMYYNEKYGGPNHHLPLPDNWM--AQVEPETQAMIQWLKNYNFVLSANLHGGAVVANYPYDKSKEIRMRGFTRSTYSSTPDDALFKELAKTYSYAHGWM----HTGYNCDDFFYEGITNGASWYSLYKGMQDFNYLHTNCFEITLELSCDKFPREEELEQEWNGNREALLTYIDKVHQGIKGMITDENGNG---IANAVISISE---------IAHDVTSGIGGDYFRLLLPGTYEVTASAEGY 394          

Query:   74 VFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKST---VDG--KNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGF 1267
            +FL+ E +  + + HH   +L   L  + ++C  IT +Y      + ++V    LYVI F  +P  H    PEFKYVGNMHGNEV+GRELL+ LA++LC+++   NE V  ++++TRIHILPSMNPDG+++A       N ++ GR N   VDLNRNFPDL+ V++ N + G    HL         ++E ET  +I W+ +  FVLSAN+HGG VVANYPYDKS    + G  ++  S TPD+ +FK LA +YS  +  M     +  N D    +GITNGA WYSL  GMQDFNYL TNCFEITLE+ C KFP  + L   W  N ++L+ +I   H GIKG++   + +G   +A AVI I+          I H VT+   GDY+RLL+PG Y V A+A G+
Sbjct:   11 LFLLCEVAASLSFFHHRYDDLVRALYNVQNQCPYITRVY-----SIGRSVQGRHLYVIEFSDNPGIHELLEPEFKYVGNMHGNEVLGRELLIQLAEFLCEEYRNNNERVTRLIQTTRIHILPSMNPDGYEVAADQGPEGNGYLTGRYNYRQVDLNRNFPDLNTVMYYNEKYGGPNHHLPLPDNW-MAQVEPETQAMIQWLKNYNFVLSANLHGGAVVANYPYDKSKEIRMRGFTRSTYSSTPDDALFKELAKTYSYAHGWM----HTGYNCDDFFYEGITNGASWYSLYKGMQDFNYLHTNCFEITLELSCDKFPREEELEQEWNGNREALLTYIDKVHQGIKGMITDENGNG---IANAVISISE---------IAHDVTSGIGGDYFRLLLPGTYEVTASAEGY 394          

Query:   86 LEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFK-RKDSCPNSD----FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKV-LNFRLE 1342
            L+    I + +H   EL+  L  +  +C++I+ +Y      V ++     L VI    +P  H PG PEFKY+GNMHGNE VGRELL+FLA YLC+++  GNE + N++ STRIHI+PS+NPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N + G   +HLL   KK +D++ +L  ET  VI WI  IPFVLSAN+HGGD+VANYPYD++     ++ S  PD+ +F+ LA +YS +NP M    +  C  +D    F+  DG TNG  WYS+ GGMQDFNYL++NCFEIT+E+ C KFP  + L  +W  N  SL+++++  H G+KG V  R   G  P+A A I          V+ I H VT+A +GDY+RLL PG Y + A+APG+ +  + V V     FS  V ++F LE
Sbjct:   43 LQQEDGISFEYHRYPELREALVSVWLQCTAISRIY-----TVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNLKKIVDQNSKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGTAHEYSSCPDDAIFQSLARAYSSFNPVMSDPNRPPCRKNDDDSSFV--DGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKSYWEDNKNSLISYLEQIHRGVKGFV--RDLQG-NPIANATI---------SVDGIDHDVTSAKDGDYWRLLAPGNYKLTASAPGYLAITKKVAVP----FSPAVGVDFELE 450          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTV-----DGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNNPLCNEIANELKQFKIVRSEKDMLVKEMKG 1465
            + +RHH   +L   L +++++C  IT LY     ++ ++V    LYV+ F   P  H P  PE KYVGNMHGNEV+GRELLL L+++LC++    N+ +  +++ TRIHILPSMNPDG+++A       + ++VGR NAN VDLNRNFPDL+   + NS+ G    HL       + ++E ET  VI WI S+ FVLSAN+HGG VVANYPYDKS         +   S TPD+E+F+ LA  YS Y      +  +C   D+ P DGITNGA WYSLS GMQDFNYL TNCFEITLE+ C KFP  + L   W+ N ++L+ F++  H GIKG+VL  + +    +  AVI +T +          H VT+   GDY+RLL+PG YSV A APG+  +   V V         V++F+L+ + SQ       P   +     KQ +  R +KD   K  +G
Sbjct:   21 VTFRHHRYDDLVRTLYKVHNQCPDITRLY-----NIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKNGGPNHHLPLPDNW-KSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYS-YAHGWMHQGWNC--GDYFP-DGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNN---LTGAVISVTGIN---------HDVTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTV---GPAGPTVVDFQLKRSSSQVYPVQRAPGRGQ-GGRAKQPRTSR-KKDPATKRHRG 455          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA---NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFK-NSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKST-VDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEP 1345
            I + HH+  ++  +L+R   +CS +   Y      + ++     L VI F   P +H    PE K +GN+HGNEV GRE+L++LA YLC +++ GN  ++ ++ +TRIH+LPSMNPDG+++A       N W  GR NA N+DLNRNFPDL    ++  S  G + DH+   +     ++  ET  ++ WI +IPFVLSA++HGGD+V +YP+D S     K   S TPD ++FK LA +Y+  +P M  R ++    +FL +  I NGA WYS +GGM DFNYL TNCFEIT+E+GC KFP  + LY  W  N + L+NF++  H GIKG+V   ++   KPV  A I +           I H VTTA +GDY+RLL PG + VIA APG+   ++ V +    + + +V +F L P
Sbjct:  188 IRFAHHSYAQMVRVLKRTAARCSQVAKTY-----SIGRSFEGKDLVVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREVLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLASTRGVRTDHIPISQYYWWGKVAPETKAIMKWIQTIPFVLSASLHGGDLVVSYPFDFSKNPHEKKMFSPTPDEKMFKLLARAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYGLWQQNKEPLLNFLEMVHRGIKGMV---TDKYGKPVKNARILVKG---------IRHDVTTAPDGDYWRLLPPGSHIVIAQAPGYSKVMKRVTIPLRMKKAGRV-DFILHP 588          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPN---SDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRL--EPADSQNEVK 1369
            ++ HH+  +++  L R  ++  +IT LY L      K+V +  LYV+    +P  H PG PEFKY+GNMHGNEVVGRELLL L +YLC ++   +  V ++V STRIH++PSMNPDG++ +    +  VVGR N+NN DLNRNFPD    +                     +  + ET+ V++W+ + PFVLSAN+HGG +V NYPYD +   G    S +PD+ VF+ +ALSYSK N +MF+ +  C +   +++ P  GITNGA WY++ GGMQD+NYL TNCFE+T+E+GC K+P    L  +W  N +SL+ F++  H G+KG VL  ++   + +  A + +  +          H VTT   GDY+RLLVPG Y + A+A G+    + V V +E    A  +NF L    AD+ NE K
Sbjct:  499 DFHHHHFPDMEIFLRRFANEYPNITRLYSL-----GKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLC-KNFGTDPEVTDLVRSTRIHLMPSMNPDGYEKSQEGDSISVVGRNNSNNFDLNRNFPDQFVPI--------------------TEPTQPETIAVMSWVKAYPFVLSANLHGGSLVVNYPYDDNE-QGVATYSKSPDDAVFQQIALSYSKENSQMFQGR-PCKDMYLNEYFPH-GITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPFENELPKYWEQNRRSLIQFMKQVHQGVKGFVLDATDG--RGILNATLSVAEIN---------HPVTTYKAGDYWRLLVPGTYKITASARGYNPVTKNVTVRSE---GAVQVNFTLVRSSADANNESK 881          

Query:  275 IPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANR-------TRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCP-NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKS-QIQCVLVTNESQFSAKVLNFRLEPA 1348
            +PG P+ K VGNMHG+E V R++L++LA  L   +  G+  +  ++ +T +++LPS+NPDG++ A         +      GR N+   DLNR+FPD     F   E            ++DE     E   +I WI    FVLS N+HGG VVA+YP+D S         S T D+EVF++LA +Y+  +P M   +  CP + D   KDGITNGA WY + GGMQD+NY+  NCFEITLE+ C K+P    L   W  N +SL+  I+  HIGIKG V          V  + ++   ++ AG    I H++TT   GD++RLLVPG Y++ A + G+    I  ++V    +  A  ++F L P 
Sbjct:  125 LPGRPQVKLVGNMHGDETVSRQVLVYLARELASGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGLGDSGPPGTSGRDNSRGRDLNRSFPDQ----FSTGE----------PPSLDEVP---EVRALIDWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKTTGLYSKTSDDEVFRYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGIKGFV-------KDSVTGSGLENATISVAG----INHNITTGRFGDFHRLLVPGTYNLTALSTGYMPLTINNIMV---KEGPATEMDFSLRPT 461          

Query:   77 FLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPN-SDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVL 1327
            F++  +S    YR+H+  +L   L  +      IT+L  L      ++V    ++ +     P+   P  P+ ++V  +HGN  VG ELLL LA++LC  +   N  V  +V+ TRI I+PS+NPDG + A         G TNA+  DL+ +F          S   + +      K I E+ ++++            F LS  + GG V+  YPYDK     +N+       E  K LA  Y+  +P M   + SCPN SD     G+  GA+W+S  G M+D++    +C EIT+   C  FP    L   W  N KSL++ +   H G+ G+V  + ++G KP++KAVI +               V T   G ++ LL PG +++ A A G++ Q   V V +++  S  ++
Sbjct:  917 FMLSSSSDLALYRYHSYKDLSEFLRGLVMNYPHITNLTTL-----GQSVEYRHIWSLEISNKPNISEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNY-KRNPVVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSKTGHTNAHGKDLDTDF---------TSNASQPE-----TKAIIENLIQKQD-----------FSLSIALDGGSVLVTYPYDKPVQTVENK-------ETLKHLASLYANNHPSMHMGQPSCPNNSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAAQLPALWAENKKSLLSMLVEVHKGVHGLV--KDKAG-KPISKAVIVLNEGIK----------VYTKEGGYFHVLLAPGVHNINAIADGYQQQHTQVFVHHDAASSVVIV 1283          

Query:   68 IFVFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN--QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQ-FSAKVLNFRLEPADSQNEVKTNNPLCNEI 1396
            +++ L+L     +++R+H+   ++  L+ +    SSITHL+      + K+V    L+V+  G++P  H  GIPEFKYV NMHG+E VGRELLL L DYL   +    E + ++++STRIHI+PSMNPDG++   +    +  GR N NN DLNRNFPD     F+N+ + +                + ETL ++ W+ +  FVLSAN+HGG +VA+YP+D            SLTPD++VF+ LA +Y+  NP M K  D C N    P +GI NG  WY L GGMQD+NY+   CFEITLE+ C K+P  + L  FW  N  SL+ +I+  H+G+KG V  +S +   P+   ++++ +      + P      T   G+YY LL+PG Y +    PG  S +  + +  +SQ FSA   +F L      + +  +NP C  I
Sbjct:    6 LWLGLLLPVVAALDFRYHHQEGMEAFLKSVAQNYSSITHLH-----SIGKSVRGRNLWVLVVGQTPKEHRVGIPEFKYVANMHGDETVGRELLLHLIDYLVSSYRKDPE-ITHLIDSTRIHIMPSMNPDGFEAVQKPDCYYSNGRENYNNYDLNRNFPD----AFENNNVTK----------------QPETLAIMEWLKTETFVLSANLHGGALVASYPFDNGVQATGTLLSRSLTPDDDVFQHLAYTYASRNPNMTK-GDQCKNKRNFP-NGIINGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPLFWNDNKASLIEYIKQVHLGVKGQVFDQSGA---PLPNVIVEVQD---RKHICPF----RTNKLGEYYLLLLPGSYVINVTVPGHDSYLTKLTIPGKSQPFSALKKDFHLPLRWQPDSISVSNPSCPMI 413          

Query:   53 KYLCLIF-----VFLVLEASG---KIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFK-RKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            K +C I      V  ++ A+G   +I + +H   EL+  L  +  +C +I  +Y      + ++     L V+    +P  H PG PEFKY+ NMHGNE VGRELL++LA YLC+Q+  GNE + +++ STRIH++PSMNPDG++ A     E   W VGR+NA  VDLNRNFPDLD++++ N   G   +HLL   KK +DE+ +L  ET  VI WI  IPFVLSAN+HGGDVVANYPYD++     ++ S +PD+ +FK LA ++S YNP M   ++  C   + D   KDGITNG  WYS+ GGMQDFNYL++NCFEITLE+ C KFP+   L  +W  N  SL+N+I+  H G+KG V  R   G  P+  A I          VE I H +TTA +GDY+RLL  G Y V A+APG+ + I+ V V +     A  ++F LE
Sbjct:    2 KQICSIVLLGAAVVSLVSAAGSDSEISFEYHRYEELRKALVSVWLQCPTIARIY-----TIGESFEGRELLVLEMSDNPGTHEPGEPEFKYIANMHGNEAVGRELLIYLAQYLCNQYQQGNETIIDLIHSTRIHLMPSMNPDGFEKAASQPGEIKDWFVGRSNAQGVDLNRNFPDLDRIIYTNEREGGANNHLLQNMKKAVDENTKLAPETKAVIHWIMEIPFVLSANLHGGDVVANYPYDETRTGSTHEYSASPDDVIFKSLAKAFSIYNPVMSDPQRPPCRKHDDDSSFKDGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPNEDTLKTYWEQNRNSLVNYIEQVHRGVKGYV--RDLQG-NPIFNATIS---------VEGIDHDITTAKDGDYWRLLRQGNYKVAASAPGYLTVIKKVAVPHS---PATRVDFELE 428          

Query:   86 LEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSC----PNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            L+    I + +H   EL+  L  +  +C++I+ +Y      V ++     L VI    +P  H PG PEFKY+GNMHGNE VGRELL+FLA YLC+++  GNE + N++ STRIHI+PS+NPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N + G   +HLL   KK +D++ +L  ET  VI WI  IPFVLSAN+HGGD+VANYPYD++     ++ S +PD+ +F+ LA +YS +NP M    +  C     +S F+  DG TNG  WYS+ GGMQDFNYL++NCFEIT+E+ C KFP  + L  +W  N  SL+++++  H G+KG V  R   G  P+A A I          VE I H VT+A +GDY+RLL+PG Y + A+APG+ +  + V V       A  ++F LE
Sbjct:   43 LQQEDGISFEYHRYPELREALVSVWLQCTAISRIY-----TVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPCHKNDDDSSFV--DGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFV--RDLQG-NPIANATI---------SVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAVTKKVAVPYS---PAAGVDFELE 450          

Query:   86 LEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSCPNSD----FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            L+    I + +H   EL+  L  +  +C++I+ +Y      V ++     L VI    +P  H PG PEFKY+GNMHGNE VGRELL+FLA YLC+++  GNE + N++ STRIHI+PS+NPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N + G   +HLL   KK +D++ +L  ET  VI WI  IPFVLSAN+HGGD+VANYPYD++     ++ S +PD+ +F+ LA +YS +NP M    +  C  +D    F+  DG TNG  WYS+ GGMQDFNYL++NCFEIT+E+ C KFP  + L  +W  N  SL+++++  H G+KG V  R   G  P+A A I          VE I H VT+A +GDY+RLL+PG Y + A+APG+ +  + V V       A  ++F LE
Sbjct:   43 LQQEDGISFEYHRYPELREALVSVWLQCTAISRIY-----TVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFV--DGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFV--RDLQG-NPIANATI---------SVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYS---PAAGVDFELE 450          

Query:   86 LEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSCPNSD----FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKV-LNFRLE 1342
            L+    I + +H   EL+  L  +  +C++I+ +Y      V ++     L VI    +P  H PG PEFKY+GNMHGNE VGRELL+FLA YLC+++  GNE + N++ STRIHI+PS+NPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N + G   +HLL   KK +D++ +L  ET  VI WI  IPFVLSAN+HGGD+VANYPYD++     ++ S  PD+ +F+ LA +YS +NP M    +  C  +D    F+  DG TNG  WYS+ GGMQDFNYL++NCFEIT+E+ C KFP  + L  +W  N  SL+N+++  H G+KG V  R   G  P+A A I          V+ I H VT+A +GDY+RLLVPG Y + A+APG+ +  + V V     FS  V ++F LE
Sbjct:   43 LQQEDGISFEYHRYPELREALVSVWLQCTAISRIY-----TVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQRGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNLKKIVDQNSKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGTAHEYSSCPDDAIFQSLARAYSSFNPVMSDPNRPPCRKNDDDSSFV--DGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKSYWEDNKNSLINYLEQIHRGVKGFV--RDLQG-NPIANATIS---------VDGIDHDVTSAKDGDYWRLLVPGNYKLTASAPGYLAITKKVAVP----FSPAVGVDFELE 450          

Query:   86 LEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFK-RKDSCPNSD----FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKV-LNFRLE 1342
            L+    I + +H   EL+  L  +  +C++I+ +Y      V ++     L VI    +P  H PG PEFKY+GNMHGNE VGRELL+FLA YLC+++  GNE + N++ STRIHI+PS+NPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N + G   +HLL   KK +D++ +L  ET  VI WI  IPFVLSAN+HGGD+VANYPYD++     ++ S  PD+ +F+ LA +YS +NP M    +  C  +D    F+  DG TNG  WYS+ GGMQDFNYL++NCFEIT+E+ C KFP  + L  +W  N  SL+++++  H G+KG V  R   G  P+A A I          V+ I H VT+A +GDY+RLL PG Y + A+APG+ +  + V V     FS  V ++F LE
Sbjct:   43 LQQEDGISFEYHRYPELREALVSVWLQCTAISRIY-----TVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNLKKIVDQNSKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGTAHEYSSCPDDAIFQSLARAYSSFNPVMSDPNRPPCRKNDDDSSFV--DGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKSYWEDNKNSLISYLEQIHRGVKGFV--RDLQG-NPIANATI---------SVDGIDHDVTSAKDGDYWRLLAPGNYKLTASAPGYLAITKKVAVP----FSPAVGVDFELE 450          

Query:   59 LCLIFVFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRT-----RNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDE--LERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSC----PNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEP 1345
            LC + + L  E S  +E +HHN  E+ + + +I+ KC  IT  Y L      KTV N  L V+    +P +H  G PEFKYVGNMHGNEVVGRELLL L DY+CDQ+ AGN+ +  ++ESTRIHI+PSMNPDGW+IA  +     + +W+ GR+NANNVDLNRNFPDLD++V++N E   K +H + +KT D+ +  ++ ET M + WI  +PFVLS+N+HGGD+VANYPYD+S      + S +PD+  F++LA SYS ++  M K  +SC     N  FL + G TNGA WYS++GGMQDFNYL TNCFEITLE+GC K+P    L  FW  N  +L+NF+  THIGIKG++  R     K +A A +K+ N+T+   +    H +T+A +GDY+RLL+PG Y V   APG+  Q +C+ VTN  +  AK ++F L+P
Sbjct:    7 LCSLAIVLFGECSS-VELKHHNYKEMLDYMVKIHKKCPEITRPYVLEG----KTVMNRSLAVLEMSDNPGKHEIGEPEFKYVGNMHGNEVVGRELLLALLDYMCDQYKAGNKTIVKLLESTRIHIMPSMNPDGWEIATESFKKTGKKDWLKGRSNANNVDLNRNFPDLDRIVYRNHE---KNNH-IKEKTHDQQKNPIQPETYMAMEWIQEVPFVLSSNLHGGDLVANYPYDESQSGAPQEYSKSPDDSTFRYLAESYSLWHATMAKPHESCDDMPDNEKFLKQKGTTNGAAWYSVAGGMQDFNYLRTNCFEITLELGCDKYPPENALPQFWEDNKDALINFMWQTHIGIKGVI--RDAQTKKGIASATVKVHNLTSDADIN---HDITSAHDGDYWRLLIPGSYMVTVTAPGYLPQTKCMEVTNPFRTEAKEVDFELQP 432          

Query:   38 YYFMNKYLCLIFVFLVLEASGKIEYR-HHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVT-----NESQFSAKVLNFRLEPAD 1351
            YYF    L L F+  VL ++  I+++ HH+  +++ I  R+ +KC  I+ +YYL S   ++T + NRL VIA GK  DR   GIPEFKY+ NMHG+EVVGRELL+ LA YLCD+ ++ N +V  ++  TRIHILPSMNPDGW IA+  RN +  GR N+  VDLNR+FPDL K  F N + G   DH+     ID  + + ET MV+ W+    FVLSANIHGGD+VANYP+D+S + G +  S+TPDN  F  LA SY+  + RM K    C +SD    DGITNGAKWYSL+GGMQD+NYL TNCFEITLE+GC+K+PD   L  +W  N  +L+N+I   H GIKG V G  ES   P+  A+IK+TN+T +    PILH++ T   G+YYRLL  G+Y V A   GF+  + C+ V      N     AK ++F L P +
Sbjct:    2 YYF----LGLFFIQTVLCSTVTIKWQNHHSEADIERIFRRVVEKCPDISFMYYLTSDRANETENGNRLLVIALGKHADRSERGIPEFKYIANMHGDEVVGRELLIRLAVYLCDEFISQNAFVHKLLSKTRIHILPSMNPDGWDIASSNRNMYSFGRDNSKQVDLNRDFPDLTKKFFSNLQSGGPLDHI-QPDEIDVQKAQIETKMVMDWLDKFNFVLSANIHGGDLVANYPFDRS-ITGNSTESITPDNPTFVELAESYADLHHRMKKGIKECYDSDNYFNDGITNGAKWYSLNGGMQDYNYLHTNCFEITLELGCKKYPDASELPRYWNENKMALLNYIIQVHRGIKGTVYGYVESTLIPMENAIIKVTNITNSANPVPILHNINTDQFGNYYRLLTKGKYIVTALVDGFEPAVACIDVQHVPSINGPFIEAKQVDFLLLPTN 439          

Query:   65 LIFVFLVLEASGKIEYR-HHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV-----TNESQFSAKVLNFRLEPAD 1351
            L FV  VL ++  I ++ HH+  +++ I+ R+ ++C  I++ YYL +G    T + NRL+VIAFG+  +    GIPEFKY+ NMHG+EVVGRELL+ LA YLCD+ ++ N ++  +V  TRIHILPSMNPDGW+IA   ++    GR N+  VDLNR+FPDL K  ++N   G   DHL     ID ++ + ET MV+ W+  I FVL AN+HGGD+VANYP+DKS + G +  S+TPDN  F  LA SY+  +PRM K    C +SD    DGITNGA+WYSL+GGMQD+NYL TN FEITLE+GC KFP+   L  +W  N  SL+N+I   H GIKG V G +E+ Y PV  A+IK+ N+T    + PILH++ T   GDYYRLL  G+Y V A+A GF   I CV V      N     A+ +NF L P +
Sbjct:    7 LFFVHTVLSSTISISWQNHHSQADIERIVGRVVERCPDISYAYYLTTGRTTTTQNGNRLFVIAFGRHANASERGIPEFKYIANMHGDEVVGRELLIRLAVYLCDEFISQNAFIHRLVNRTRIHILPSMNPDGWEIAASNKDFHEFGRGNSKRVDLNRDFPDLAKKFYRNLRNGGPLDHL-QPDEIDVEKAQIETRMVMEWLDKINFVLGANMHGGDLVANYPFDKS-ITGNSAESITPDNPTFVELAESYADKHPRMKKGIKKCYDSDNHFNDGITNGARWYSLNGGMQDYNYLHTNSFEITLELGCEKFPNASELPRYWNENKMSLLNYILQVHRGIKGTVYGYAENTYIPVENAIIKVANITDPTTLTPILHNINTDQFGDYYRLLTKGKYIVTASADGFIPAIACVDVHYTPSINGPFLEAQQVNFLLLPTN 439          

Query:   47 MNKYLCLIFVFLVLEASGKIEY-RHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSC-PNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV 1294
            MN+++ L+   +      KI +  HHNN EL  IL  ++ KC +I+ LYYL +GD + T   NRLYV+  G +P  H+P IPE K V NMHGNEVVGRELLL LA YLCD++  G+  V  +++ TRIH+LPSMNPDG++ A+      + GR NAN+VDLNRNFPD D++ F+ SE+ R     +  +       E ETLM+  W+  IPFVLSANIHGG +VANYP+D S +DG  + S +PD+  F+ LA SYSKYN  M  ++  C PN +F  K+GITNGA WYS+S GMQD+NY+ +NCFE+TLE+ C K+P    L +FW  N KSL+NFI   H G+KG+V GRS  G  P+A A I++ N+T       I H+VT+   GDY+RLL PG+Y + A  PG++  +  V +
Sbjct:   12 MNRFVVLVLCVVASCNGKKINWLEHHNNQELFEILNDVHRKCRNISELYYLTAGDRETTKLGNRLYVLVIGGNPKMHVPLIPEVKLVANMHGNEVVGRELLLRLAKYLCDKYKEGDGLVNWLIQHTRIHLLPSMNPDGYEQADEREKNGLSGRNNANDVDLNRNFPDSDQLAFQ-SEMDRNSRLEILAEYQRIPRPETETLMIEEWLREIPFVLSANIHGGALVANYPFDGS-IDGDTKPSPSPDDATFQALARSYSKYNMAMKTQRPKCAPNENF--KEGITNGAAWYSVSNGMQDYNYMESNCFELTLEISCEKYPSATKLPEFWKENRKSLLNFILQVHGGVKGMVYGRSADGQLPLADATIRVVNITDPDDPVHIRHYVTSNQNGDYFRLLRPGKYLIGAIKPGYEPMLINVTI 425          

Query:  113 RHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANR---TRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELG-RKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRK----DSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEP 1345
            ++H++ +LKNILE IN KC++ T LY + S     +V    LYVI    +P +HIP  PE KYV NMHGNE +GRELLL LA YLCD+ + GN+ +  +V ST IHILP+MNPDG++ A R   T   W+ GR NAN VDLNR+FPDLDKV ++ ++ G  + DHLL+    D  + + ET  V  W+ S+PFVLSANIH GD+VANYP+D +     NQ S +PD++ F+FLA +Y+K +  M K      D+ P   F  + GITNGAKWYS++GGMQDF+YLA+N FEITLEV C KFPD K L   W  N K+L+ FI   H GIKGIV    E+G +P+++AV+ + N+T    + PI H VTT   GDYYRLL PG+Y V+  A G++     V VTN ++ SA+++NF+L+P
Sbjct:   46 QYHDHEQLKNILENINKKCANYTELYSIGS-----SVEGRELYVITLSTTPGQHIPLKPEMKYVANMHGNEPIGRELLLRLASYLCDEILKGNKDILQLVNSTSIHILPTMNPDGFEAALRTDSTERNWMKGRKNANGVDLNRDFPDLDKVFYELTDTGVPRYDHLLD-LIRDTTKHQPETQAVGMWLLSLPFVLSANIHEGDLVANYPFDSAREPNVNQYSTSPDDKTFRFLAETYAKNHAHMAKNDHPPCDASPFDAFANQGGITNGAKWYSVAGGMQDFSYLASNAFEITLEVACNKFPDPKQLPQLWNENKKALIEFIWTVHSGIKGIV-SDEETG-EPISEAVVWVRNIT---DLTPIKHPVTTWLTGDYYRLLTPGKYQVLVTATGYEPATATVEVTNANRTSAQIVNFKLKP 453          

Query:   92 ASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF--KRKDSCPNSDFLP-KDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNF 1333
             SG I + +H   EL+  L  +  +C SI+ +Y      V ++     L V+    +P  H PG PEFKY+GNMHGNE VGRELL++LA YLC+++  GN+ + N++ STRIHI+PSMNPDG++ A     E   W VGRTNA  +DLNRNFPDLD++V+ N   G   +HLL   KK +DE+ +L  ET  VI WI  IPFVLSAN+HGGDVVANYPYD++     ++ S             +YS YNP M   KR     N D    K+GITNG  WYS+ GGMQDFNYL++NCFEITLE+ C KFP    L  +W  N  SL+N+++  H G+ G V  R   G  P++ A +          VE I H +TTA +GDY+RLL PG Y V A+APG+ + I+ V V   S  +A  L+F
Sbjct:   36 GSGGISFEYHRYEELRKALVAVWLQCPSISRIY-----TVGESSEGRELLVLEISDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIYLAQYLCNEYQQGNDTIINLIHSTRIHIMPSMNPDGFEKAASQSGEMKDWFVGRTNAQGIDLNRNFPDLDRIVYMNEREGGANNHLLKNMKKAVDENTKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRSGSTHEYS-------------AYSVYNPVMSDPKRAPCRKNDDDSSFKEGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPPENTLKMYWDQNRNSLINYLEQVHRGVAGFV--RDLQG-NPISNASV---------SVEGIDHDLTTAKDGDYWRLLTPGNYKVSASAPGYLTVIKKVAV---SSTTATRLDF 425          

Query:   65 LIFVFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTR---NEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKS---TVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPA 1348
            L+ V    EA    +++HH   E+   L  +  +C  IT +Y      + ++V    LYV+ F  SP  H    PEFKYVGNMHGNEV+GRELL+ L  +LC++++AGN+ + +++ +TRIHILPSMNPDG+++A R     N ++VGR N+  VDLNRNFPDL+ +++   E    Q+H L      E ++E ETL VI W+ +  F+LSAN+HGG VVANYP+DKS    + GK+  S TPD+++FK LA +YS  +  M K  +     D+  ++GITNGA WYSLS GMQDFNYL TNCFEITLE+ C KFP    L   W+ N ++L+++++  H GIKG+V   + +   P+  A I +  ++         H +TT  +GDY+RLL+PG Y+V A+A G++     V V       A  L+F L+PA
Sbjct:   10 LLLVLWAPEAQAIDDFQHHGYEEMVRALFSVQSQCPYITRIY-----SIGRSVEGRHLYVLEFSDSPGIHEALEPEFKYVGNMHGNEVLGRELLIHLCQFLCEEYLAGNQRITSLIHNTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNSREVDLNRNFPDLNGLMYY-YEKNNGQNHHLPLPDKWELQVEPETLAVIKWMQNYNFILSANLHGGAVVANYPFDKSREARIRGKSTYSATPDDKIFKKLAKAYSYAHSWMHKGWNC---GDYF-EEGITNGANWYSLSKGMQDFNYLYTNCFEITLELSCDKFPPASALSREWLANREALVSYMEQVHHGIKGMVYDENNN---PIGNAEISVAGIS---------HDITTGPDGDYFRLLLPGTYTVTASAAGYQPYSSTVTV---GPAEAIQLHFYLKPA 418          

Query:   83 VLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE-------------WVVG-RTNANNVDLNRNFPDLDKVVFKNSELGR-KQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVD-GKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPA 1348
             +E S  I++ HH+N ++ NIL++  ++CS I+  Y      + ++V    L VI F  +P  H+   PE KY+GNMHGNE +GRELL++LA YLC +++ GN  ++ ++ +TRIHILPSMNPDG+++A                   W +G R NA N+DLNRNFPDL  +V+    L R + DH+    +    ++  ET  V+ WI SIPFVLSAN HGGD+V +YPYD S      N  S TPD +VFK +A +Y+  +  M         ++F+ K GI NGA+WYS++GGM DFNYL TNCFEIT+E+GC KFP  + L+  W  N ++L+ ++++ H GIKG V      G        IK   V+  G    I H +TTA +GDY+RLL PG + V A+APG+   ++ V +    + + +V +F L+ A
Sbjct:  177 TMEPSTIIQFTHHSNTQMFNILKKTAEQCSHISRTY-----SIGQSVERRDLLVIEFSNNPGEHVLLEPEVKYIGNMHGNEAMGRELLIYLAQYLCSEYLLGNSRIQTLINTTRIHILPSMNPDGYELAYSELQSGFDTDYDEDAGFSWQIGGRYNAQNIDLNRNFPDLTSLVYNRRRLKRFRSDHIPIPDSYWLGKVAPETYAVMKWIRSIPFVLSANFHGGDLVVSYPYDFSKHPLETNMFSPTPDEQVFKQIARTYANAHATMSNHDTDRCGANFVDKGGIVNGAEWYSIAGGMADFNYLHTNCFEITVELGCDKFPVEEDLHTGWEENKEALLTYLESVHKGIKGFVKDEDGRG--------IKRATVSVRG----IRHEITTAEKGDYWRLLTPGIHIVTASAPGYTKAMKRVHLPTHMRKAGRV-DFILKKA 596          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLP----KDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKS 1273
            E+RHH+  +++  +++ + K  SIT LY      + K+V N  L+V+    +P  H  G PEFKY+GNMHGNEVVGRELLL L +YLC  +    E V  +V +TRIHI+PSMNPDG+++A   ++E  VGR N+NN DLNRNFPD  K +                     D  + ET+ V+ W+   PFVLSAN+HGG +V NYP+D    DG +Q S +PD+ VF+ LA +YSK N  M K    CP     P    KDGITNGA+WY++ GGMQD+NY+ TNCFE+T+E+GC K+P    L  +W  N +SL+ FI   H G+KG+V           +K    I N T    VE I H VTT   GDY+RLLVPG+Y +  +A G+ S
Sbjct:  413 EFRHHHYSDMELFMQKFSSKYPSITRLY-----SIGKSVENRMLWVMEISDNPGEHEQGEPEFKYIGNMHGNEVVGRELLLNLIEYLCRNYGTDLE-VTQLVNTTRIHIMPSMNPDGYEVAQEGKDELRVGRNNSNNYDLNRNFPDQFKTI--------------------TDPRQPETIAVMDWVKRYPFVLSANLHGGSLVVNYPFDDDP-DGISQYSKSPDDAVFQMLATAYSKENTLMHK-GHPCPEIAVYPDEYFKDGITNGAQWYNVPGGMQDWNYINTNCFELTIELGCEKYPLADELPRYWEQNRRSLLQFIHQVHRGVKGLVTD---------SKDGTGIPNATIT--VEGIDHSVTTNKVGDYWRLLVPGKYHLTVSAQGYTS 766          

Query:   89 EASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWV-VGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCP-NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQI 1279
            E  G+   ++++ +EL  IL+ +  K   I++L       + ++V    L+V+     P   +PG P+FKYVGNMHG+E V R++L++L ++L   +   +  V  ++ ST I+I+PSMNPDG++ A     +     R+NA +VDLNR+FPD                   +   + EDE   +T  V+ WI    FVLS N+HGG VVA+YP+D S + G +  S +PD+ +F++LA  Y++ NP M   K  CP +   + KDGITNGAKWY ++GGMQD+NYL+ NC EIT+E+ C K+P    L   W  N ++L+ +++  HIG++G V  R     KP++ A+I +  +          H+V+TA  GDYYRLL+PG Y++ A A G  + I
Sbjct:   44 EEPGETYSKYYSFVELSRILKSLAQKYPHISNL-----SSIGRSVQGRELWVMRISSEPAAQVPGKPKFKYVGNMHGDETVSRQVLVYLIEHLLTGY-GEDPRVNELINSTDIYIMPSMNPDGFERAVEGDCDGDDKARSNAKDVDLNRSFPDQ-----------------FSDINVSEDEAPEKT-AVMKWILENKFVLSGNLHGGTVVASYPFDDSALHGGSIYSESPDDSLFRYLARVYAENNPIMKTGKPKCPLDPSEMFKDGITNGAKWYDVAGGMQDYNYLSGNCLEITMELSCCKYPPAAQLQTEWENNREALLAYMEKVHIGVRGFV--REAGSGKPLSDAMIMVAGIN---------HNVSTAQFGDYYRLLLPGTYNITAVASGASTDI 407          

Query:   92 ASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
             S  + YRH+   EL   L  +N    +IT L  L      +T+     + +     P+   P  P+ ++V  +HGN  VG ELLL  A +LC  +   N+ +  ++  TRI ILPS+NPDG ++A        VG TNAN  DL+ +F D                             + ET  V+  I    + LS  + GG V+  YPYDK     +N+++L       ++LA  Y+  +P M      CPNS     DG+   A+ +S  G M+DF+    +C EIT+   C  FP    L   W+ N KSL++ +   H G++GIV  + +SG KP+  A+I +      G V      V T+  G ++ LL PG +++ A A G++ Q Q V+V++    ++ V+ F ++
Sbjct:  834 TSTTLRYRHYK--ELSEFLRGLNFNFPNITSLQRLGQSAEYRTI-----WALEISNKPNVPEPSEPKIRFVAGIHGNAPVGTELLLEFAAHLCINY-GKNDAITRLINETRIVILPSINPDGRELAKEKECSSPVGMTNANGKDLDTDFFDP----------------------------QPETRAVMDLIQEKGYTLSVALDGGSVLVTYPYDKPVQPVENESTL-------RYLATVYANNHPTMHLGNTGCPNSMGNIPDGVLRAAEKHSHMGSMKDFSVDFGHCPEITVYTSCCLFPQADQLSVLWVENRKSLLSMLVEVHKGVRGIV--KDKSG-KPIVGAMIVLN-----GGV-----RVFTSEGGYFHALLAPGSHNIEAVAEGYQQQRQEVIVSSYEAANSIVIEFDMD 1194          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIA----------------NRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGR-KQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKST-VDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKV 1324
            +++ +H+N ++ NIL++   KC  I+  Y      + ++V    L VI F K+P +H    PE K +GNMHGNEV+GR+LL++LA YLC +++  NE ++ ++ +TRIH+LPSMNPDG+++A                    N W  GR NA N+DLNRNFPDL  + +        + DH+    +    ++  ET  V+ WI SIPFV+SA++HGG++V +YP+D S   + +   S TPD +VFK LA +Y+  +  M         + F  K GI NGA WYS +GGM DFNYL +NC E+T+E+GC KFP  + LY  W+ N ++L++F+++ H GIKGIV   + +G K    A+I +  +            VTTA +GDY+RLLVPG Y + A+APG+    + + + +  Q   +V
Sbjct:  182 LQFTYHSNAQMINILKKTAAKCPHISRTY-----SIGRSVDGKDLLVIEFSKNPGQHDLLEPEIKLIGNMHGNEVLGRQLLIYLAQYLCSEYLLANERIQTLINNTRIHLLPSMNPDGYELAASEVADSLDPENTNQEGHIYNGWTSGRANAQNIDLNRNFPDLTSIFYNRRRFRSIRNDHIPIPDSYWISKVAPETYAVMKWIRSIPFVISASLHGGELVISYPFDFSRHPEEEKMFSPTPDEQVFKQLARTYADAHATMSNNDTDRCGASFANKGGIINGALWYSFAGGMSDFNYLHSNCLELTVELGCDKFPAEEELYPEWLRNKEALLSFMESVHRGIKGIVKDGNGNGIK---GAIISVKGLR---------RDVTTAEDGDYWRLLVPGIYVISASAPGYSKVTKRIRLPHSMQKVGQV 589          

Query:  113 RHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVV------GRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRL--EPADSQNEVKTNN 1378
            RH  + E+   L R    C     LY      + K+  N  L VI   ++P +H   +PE + VGN+HGNEV+GRELL+ LA +LC +   G+E VR ++ +TR+HILPSMNPDG+++A  + +  V       GR N  N+DLNRNFPDL   V +  +  R+   L       + ++  ET  VI W+   PFVL+ N+HGG+++  YPYD S + G+   S TP++++F+ LA +Y++ +P M  K K  CP     P  GI NGA+WYS  GGM DF+YL + C E+TLE+GC KFP G+ L   W  N ++L+ F++A H GIKG+V  R E G      A I    ++  G     L    TA  G+++RLL PG Y V A+  G+++ ++ V +    Q S +V +F+L  +P  + + V+ ++
Sbjct:  179 RHRRHAEMTRALRRAEKSCGGAARLY-----SIGKSFENRDLLVIELSENPGKHELLVPEVRLVGNIHGNEVLGRELLVALAQHLCARLEDGDERVRRLLNTTRLHILPSMNPDGYELAADSVSGSVANAADSSGRNNMQNIDLNRNFPDLTSGVLRRPK--RRTQPLPVPDQYWDGKVAPETRAVIDWMEEFPFVLAGNLHGGELLVRYPYDASLM-GEKFYSATPEDQMFRLLARTYAEAHPLMSDKHKAPCPGETGAPSGGIVNGAEWYSFRGGMPDFSYLHSGCLELTLELGCVKFPSGEDLPIEWAHNREALLTFVEAVHQGIKGVV--RDERG------AGIGGARISIKGN----LRDTVTAPSGEFWRLLPPGSYIVRASRAGYRAVVKRVRLPARLQTSGRV-DFKLPRQPGTTASPVEPHD 588          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELER-------ETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGK-NQASLTPDNEVFKFLALSYSKYNPRMF-KRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQ 1357
            +++RHHN  E++ +++ +N+KC ++T +Y     ++ K+    +LY +    +P  H  G PEF+YV  +HGNE +GREL LFL ++LC ++  GN  +R +VE TRIH+LPS+NPDG++ A    +E   W  GR   N +DLN NFPDL+ V++     G     + N      D           ET  V++W+  IPFVL  N+HGG++V  YP+D +    + ++ S TPD ++F++LA  Y+  +  M    +  C   DF   +G+ NGA+W++++G M DF+YL TNCFE+T+E+ C KFP    L   W  N ++L+ F++  H GIKGIV      G   +  A+I          V+ I H VTTAS GDY+RLL PG Y V A   GF    Q   V  +    A   NF L   + Q
Sbjct:  179 LDFRHHNYKEMRLLMKIVNEKCPNVTRIY-----NIGKSHEGLKLYAMEISDNPGEHEIGEPEFRYVAGVHGNEALGRELTLFLMEFLCHEYNRGNPRIRRLVEETRIHLLPSVNPDGYEKAYEAGSELSGWTFGRWTRNGIDLNHNFPDLNSVLWDAENRGHVSHGVPNHHLPLPDWFHSRNATVAVETRAVVSWMEKIPFVLGGNLHGGELVVTYPFDAAREPWRAHEPSATPDEQIFRWLAFLYASTHRTMTDANRRVCHGQDFTKDEGVINGAEWHAVTGSMGDFSYLHTNCFEVTMELSCDKFPHETELPQEWENNREALLVFLEQVHRGIKGIVTDADGEG---IPNAIIS---------VDEINHDVTTASGGDYWRLLNPGEYRVTARKEGFVPAAQNCQVGYD--MGATRCNFTLHKTNRQ 589          

Query:  110 YRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANR--TRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPK---DGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLV 1294
            ++HHN  E  + L+ ++ +  +IT LY      + K+V    L+VIA   +P++H PG PEFKY+ NMHGNEVVG+E+LL  A YLCD +   +E V   +++TR+H+LPSMNPDG+++A +   R  W++GR+N+ NVDLNRNFPD     FK+S                  E + ET  V+ WI  +PFVLSAN+HGG +VANYP+D S   GK++ S +PD++VF+ LA +YS+ +P M          +  P    DGITNGAKWYS+SGGMQD+NY+ +NCFEIT+E GC+KFP  + L  +W  N KSL++F+   HIG+KG V        K      I    ++  G  + I     TAS+GD++RLL PG Y V A A GF+ Q + V V
Sbjct:    1 FKHHNYDETLSFLKELHGQFPNITRLY-----SIGKSVEGRDLWVIALSSTPNKHEPGKPEFKYIANMHGNEVVGKEVLLTFAKYLCDNYKKDDE-VTKALDTTRVHLLPSMNPDGYELAFKGDNRKNWIIGRSNSKNVDLNRNFPDQ---FFKSST----------------GEPQPETKAVMKWIKEVPFVLSANLHGGSLVANYPFDDSP-SGKSEYSKSPDDDVFQSLAKAYSENHPTMHLDNPPWECPEVPPDHFNDGITNGAKWYSVSGGMQDYNYVHSNCFEITVEQGCKKFPAAEELPRYWKENKKSLLSFLDMVHIGVKGFV--------KDTQGVPIPGARISVEGHKKDIF----TASDGDFWRLLNPGDYKVTAFADGFEDQTKTVTV 362          

Query:  110 YRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKD--SCPNSD---FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            +RHHN  E+  +L++ + K ++IT LY     DV  +V N +L+V+    +P +H    PE KY  N+HGNEVVG+E+LL L  YLC  +   N+ + ++V+STRIHILPS+NPDG+++A + + +   G  NAN VDLNRNFPD     F  S  G  Q                ET  ++ WI S PFVLSA++H G +VANYPYD +   G++  S TPD++VF+ LA +YS+ +P M        CP+     F+  DGITNGA+WYS+SGGMQD+NY+ +N FEITLE+GC KFP+   L ++W  N ++L+ +I+ TH G+ G+V  R E G  P+  A I ITN           H V TA +GDY+R+LVPG Y V  +A GF+ + +   V   S   A  L+F L+
Sbjct:    4 FRHHNYEEMTWLLKKYSRKYTNITRLY-----DVGTSVQNRKLWVMEISDNPGKHEVKEPEMKYTANIHGNEVVGKEMLLHLIRYLCHNY-GVNKRITDLVDSTRIHILPSLNPDGYEMAAQ-KTKTHTGTKNANGVDLNRNFPDQ----FFPSTTGPPQP---------------ETRAIMDWIKSNPFVLSASLHSGSLVANYPYDDNP-SGQSLYSATPDDDVFRQLARAYSEAHPTMHLANSPWKCPDKQREHFI--DGITNGARWYSISGGMQDYNYVHSNAFEITLELGCEKFPNASALPEYWDENKEALLGYIEQTHRGVYGVV--RDEEG-DPIENARISITNRR---------HDVFTAKDGDYWRILVPGSYEVTVSARGFEHETKVASV---SPSKATSLDFTLK 375          

Query:  104 IEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQA-SLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGR--YSVIAAAPGFKSQIQCVLVTNE 1303
            + + HHN   +K +LE+ N +   IT LY      V KTV N  L V+     P +H  G PEFKY+GNMHGNEVV RE+LL L  YL   +   +E ++ +V+STRIHI+PSMNPDG++ A     + V GR NAN +DLNRNFPD         +   ++++         + L+ ET +V++WI S PFVLSAN+HGG +VANYP+D    +GK    S +PD+ +FK LA +Y+  +  M   K  CP        GITNGA WYS+SGGMQD+NYL +N FEITLEV C KFP    L DFW  N  +L+++I   H G+KG+V    ++  KP+  A I +   +         H V +A++GD++RL++P    YSV   APG+    + V V  +
Sbjct:    3 VPFVHHNYEAMKGLLEKFNKEYPDITRLY-----SVGKTVENRDLLVLEISDKPGKHEKGEPEFKYIGNMHGNEVVSREILLQLIGYLLKNYQENSE-LKKLVDSTRIHIMPSMNPDGYEKAVMGDCQGVTGRANANGIDLNRNFPD---------QFAERKEN---------NPLQPETKLVMSWIKSNPFVLSANLHGGSLVANYPFDDYDPNGKRSGDSPSPDDPLFKSLARTYADAHKTMHLNKPPCPGDPDQFDGGITNGAHWYSVSGGMQDYNYLHSNAFEITLEVSCCKFPAASTLSDFWDKNKPALLSYINRVHTGMKGVV---QDNMGKPIKDARIILEGNS---------HAVKSAADGDFWRLVLPRNKPYSVRVEAPGYNYLTKEVRVAED 369          

Query:  110 YRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSD--FLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEP 1345
            ++HH + E+ + L+++++    IT LY         +V    L+V+    +P  H PG PEFKYVGNMHGNEVVGRE+LL L   LC+ +   +  +  +V+ TRIHI+PSMNPDG  ++     + V GR NA++VDLNRNFPD                     +  DED   E ET  +I W++  PFVLSAN+HGG VVANYP+D  T  G+ + S +PD+ VFK+LALSYS  +P M   K +CP +D   + K+GITNGA WY++ GGMQD+NYL +NCFEIT+E+ C K+P    L  FW  N  SL+ F+   HIG++G V  +S+SG + +  AVI          VE I HHV +  +GDY+RLL+ G Y + AAA G++ Q Q V+V       A   NF L+P
Sbjct:  425 FKHHTHKEMTSFLKKVHELYPHITRLY-----SAGYSVKGRELWVMEISDNPGTHEPGEPEFKYVGNMHGNEVVGREMLLLLIQVLCENYHRISS-ITALVDYTRIHIMPSMNPDGHAVSIEGDKQSVTGRPNAHHVDLNRNFPD---------------------QFSDEDGHQEPETKAIIKWLSEYPFVLSANLHGGSVVANYPFD-DTEYGEERYSKSPDDIVFKYLALSYSLAHPTMSNNKPACPETDPGEVFKNGITNGAAWYNVKGGMQDYNYLHSNCFEITVEMSCNKYPYRTQLQHFWNDNKVSLITFMAQVHIGVRGFV--KSDSG-ESIPNAVI---------SVEGINHHVLSGKDGDYWRLLLKGNYKLTAAAKGYQQQTQNVVVKRGLATEA---NFTLQP 796          

Query:  116 HHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQH-VAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN-QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQN--EVKTNNPLCN 1390
            +HN  EL  +LE  + +   I  L+      V K+V N  L+ +     PD   PG P FKYVGNMHGNE VGR++L++L  YL + +   G+E +  +V ST I+I+PSMNPDG++ +     + +VGR N NNV+LNRNFPD                   N    D    + ET  VI WI   PFVLSAN+HGG +VA+YP+D +         S +PD+E+F+ LAL+YS+++  M   K+  P      K+GITNGA WY + GGMQD NYL +NCFEITLE+ C K+P+   L   W  N  +L+ +++  H GIKG V  RS +G   +  AV+ +  +           +VTTA  GD++RLLVPG Y+V+  APGF    +  ++  +S  SA  +NF L  +  Q+    K N+P+ N
Sbjct:    1 YHNYDELTRLLESYSKRYKKIARLH-----SVGKSVLNRHLWALQITDHPDIIEPGEPMFKYVGNMHGNEAVGRQILIYLVQYLLENYGKTGHERITKLVNSTNIYIMPSMNPDGFERSKELDCDGLVGRRNENNVNLNRNFPD----------------QFNNWLDYDVSNAQPETKAVIKWIYENPFVLSANLHGGSLVASYPFDSNRYHRPFWYYSKSPDDEIFRELALTYSRHHHTM---KNGDPRCHTHFKNGITNGAYWYDVPGGMQDINYLISNCFEITLELSCCKYPNSTELPKEWKNNKNALLTYMEEVHKGIKGFVRDRSGNG---IQGAVVHVLGIKK---------NVTTARHGDFWRLLVPGNYTVLVTAPGFHQAKRTDIIVEKS--SAIEVNFVLSKSSQQSGTNFKLNDPIDN 391          

Query:  116 HHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFP-DLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYD-KSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVT 1297
            +H+   +  +L+    KC  I     +R   + K+    +++ +    +P +  P  P    VG++ G++V+GRE+LL L  YLC+ + +    V  ++++TR+H++P+++ DG     + R     G+ ++NN D++++F  D+ +    N+ + R+ D +        D + R           +   L+ N+    +   YP + + T +   + + T D + F  +A +Y++ +P+M K    C  S     +GIT GA W  +   MQD+ YL  N  +++  V C K+P           N   ++NFI+ +H  + GI+       + P+  A +++ N      +              +Y++L PG+Y + A+APG+ +  + VL+T
Sbjct:  816 YHDYKTMTQMLQSYYLKCPGI-----IRLQSIGKSQEGRKIWSLEISVNPGQENPYKPNVGMVGSLQGSDVIGREMLLALVGYLCEGYKSKEARVVKLLQTTRLHVVPAVDVDG---NEKAREGDCQGKLDSNN-DISKSFYYDMPE----NTRMRRESDKI--------DSVSR-----------VKRGLNFNV----IFQLYPLNAQYTGNPHVKGATTSDEKTFIDIATTYARSHPKM-KLGHGCNGSIPQFANGITKGATWREMHYTMQDYAYLDMNILQLSFFVSCCKYPPIDSFESILKSNAIPMINFIKKSHQALTGII---QTFNHTPIHNASLRVHNSKIKIDI--------GLKNSSFYKILAPGKYILKASAPGYSTATKEVLIT 1163          

Query:   74 VFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNF 538
            V   L A+ K  + HH   E+   ++ +  +C  I H+Y      +  +V   R++V+     P  H PG PEF YV  +HGNEVVG+E++L L  +LC  +   ++ V  +V+STR+H LP MNPDG  +A         GRTNA  VDL  NF
Sbjct: 1170 VMFTLHAAPK--FSHHQPDEIGKWMQTMAKRCPKIAHVY-----SIGMSVQFRRIWVMELSDKPGVHQPGKPEFSYVAGIHGNEVVGKEMVLLLIQHLCLSY-GKDDMVTRLVDSTRLHFLPLMNPDGGVVAQEGNCNSETGRTNARKVDLWTNF 1316          

Query:  110 YRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIAN-RTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMF--KRKDSCPN---SDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCV 1288
            ++HHN  +L   L+  + K   IT LY      +  +V N +L+ +    +P +H PG PEFKY+ N+HGNEVVGRELLL L  YLC+ +   +E VR +V++TRIHILPS+NPDG+++A+ + +    +GR NA  VDLNRNFPD     F  S  G  Q                ET  V+ WI   PFVLSA++H G +VA YPYD S   G++  S TPD++VF+ +A +YS+ +P M     K +C N     F+  DGITNGA W+S+SGGMQD+NY+ +N FE+T+EVGC +FP    L  +W  N K L+  I   H G+ G V  ++  G +P+A A IK+++           H VT+A +GDY+RLLVPG Y V A+A G++ Q + V
Sbjct:    2 FQHHNYEKLTWFLKYFSLKYPDITRLY-----SIGYSVQNRKLWAMEISDNPGQHEPGEPEFKYIANIHGNEVVGRELLLQLIRYLCENY-ESHEKVRTLVDTTRIHILPSINPDGYELASVKGKTHKFIGRRNAYGVDLNRNFPDQ----FFPSSNGPPQP---------------ETRAVMNWIRDYPFVLSASLHSGALVALYPYDDSP-SGQSLYSATPDDDVFRHVAKTYSELHPVMHLANPKWNCSNVKEEHFI--DGITNGASWFSISGGMQDYNYVHSNDFEVTVEVGCERFPKEDQLEKYWKDNKKPLLELINQVHRGVHGFV--KNIQG-EPLANAFIKVSDRR---------HDVTSAKDGDYWRLLVPGSYEVTASATGYEPQTKLV 360          

Query:   92 ASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFK-RKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            + G+I + +H   EL+  L  +  +C ++T +Y        ++     L V+    +P  H PG PEFKY+ NMHGNE VGRELL++LA YLC+Q+  GNE + +++ +TRIH++PSMNPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N   G    HLL   KK +DE+ +L  ET  VI WI  IPFVLSAN+HGGDVVANYPYD++     ++ S +PD+  FK LA +YS YNP M   ++  C   + D   KDGITNG  WYS+ GGMQDFNYL++NCFEITLE+ C KFP    L  +W  N  SL+N+I+  H G+KG V  R   G  P++ A I          VE I H +T+A +GDY+R+L PG Y V A APG+ + I+ V V       A  ++F LE
Sbjct:   21 SDGEISFEYHRYDELRKALVSVWLQCPTVTRIY-----TTGESFEGRELLVLEMTDNPGTHEPGEPEFKYIANMHGNEAVGRELLIYLAQYLCNQYQQGNETIIDLIHNTRIHLMPSMNPDGFEKAASQPGEIKDWFVGRSNAQGIDLNRNFPDLDRIVYINEREGGANHHLLQNMKKAVDENPKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRTGSTHEYSASPDDVTFKSLAKAYSMYNPVMSDPQRPPCRKNDDDSSFKDGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPSEDTLKTYWEQNRNSLVNYIEQVHRGVKGFV--RDLQG-NPISNATIS---------VEGIDHDITSAKDGDYWRILAPGNYKVAATAPGYLTVIKKVAVPYS---PAARVDFELE 426          

Query:   92 ASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNE---WVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLN--KKTIDED-ELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFK-RKDSCP--NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            + G+I + +H   EL+  L  +  +C ++T +Y        ++     L V+    +P  H PG PEFKY+ NMHGNE VGRELL++LA YLC+Q+  GNE + +++ +TRIH++PSMNPDG++ A     E   W VGR+NA  +DLNRNFPDLD++V+ N   G    HLL   KK +DE+ +L  ET  VI WI  IPFVLSAN+HGGDVVANYPYD++     ++ S +PD+  FK LA +YS YNP M   ++  C   + D   KDGITNG  WYS+ GGMQDFNYL++NCFEITLE+ C KFP    L  +W  N  SL+N+I+  H G+KG V  R   G  P++ A I          VE I H +T+A +GDY+R+L PG Y V A APG+ + I+ V V       A  ++F LE
Sbjct:   21 SDGEISFEYHRYDELRKALVSVWLQCPTVTRIY-----TTGESFEGRELLVLEMTDNPGTHEPGEPEFKYIANMHGNEAVGRELLIYLAQYLCNQYQQGNETIIDLIHNTRIHLMPSMNPDGFEKAASQPGEIKDWFVGRSNAQGIDLNRNFPDLDRIVYINEREGGANHHLLQNMKKAVDENPKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRTGSTHEYSASPDDVTFKSLAKAYSMYNPVMSDPQRPPCRKNDDDSSFKDGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPSEDTLKTYWEQNRNSLVNYIEQVHRGVKGFV--RDLQG-NPISNATIS---------VEGIDHDITSAKDGDYWRILAPGNYKVAATAPGYLTVIKKVAVPYS---PAARVDFELE 426          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTR---NEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKS---TVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQN 1360
            +++HH   E+   L  + ++C  IT +Y      + ++V    LYV+ F  +P  H    PEFKYVGNMHGNEV+GRELL+ LA +LC+++ A N+ +  ++  TRIHILPSMNPDG+++A R     N ++VGR NA  +DLNRNFPDL+ +++   E    ++H L      E ++E ETL VI W+ S  FVLSAN+HGG VVANYP+DKS    + G+   + TPD+++F+ LA +YS  +  M K  +     DF   +GITNGA WYSLS GMQDFNYL TNCFEITLE+ C KFP    L   WM N ++L+++I+  H GIKG+V   + +   P+ KA I +  +          H VT+  +GDY+RLL+PG Y+V A+APG+      V V       A  L+F L+ A  QN
Sbjct:   26 DFKHHRYEEMVRALFAVQNECPYITRIY-----SIGQSVEGRHLYVLEFSDNPGIHEALEPEFKYVGNMHGNEVLGRELLIKLAQFLCEEYQARNQRITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNAREIDLNRNFPDLNALMYY-YEKNNGRNHHLPLPDNWEQQVEPETLAVIKWMQSYNFVLSANLHGGAVVANYPFDKSRYPRIRGRTTHADTPDDKLFRKLARTYSYAHSWMHKGWNC---GDFF-DEGITNGASWYSLSKGMQDFNYLYTNCFEITLELSCNKFPPESTLPGEWMANREALVSYIEQVHHGIKGMVYDENNN---PIRKAEISVAGIN---------HDVTSGVDGDYFRLLLPGTYTVTASAPGYLPSTSTVTV---GPAEAIQLHFYLKKAKKQN 424          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTR---NEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKS---TVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            +++HH   E+   L  + ++C  IT +Y      + ++V    LYV+ F  +P  H    PEFKYVGNMHGNEV+GRELL+ LA +LC+++ A N+ +  ++  TRIHILPSMNPDG+++A R     N ++VGR NA  +DLNRNFPDL+ +++   E    ++H L      E ++E ETL VI W+ S  FVLSAN+HGG VVANYP+DKS    + G+   + TPD+++F+ LA +YS  +  M K  +     DF   +GITNGA WYSLS GMQDFNYL TNCFEITLE+ C KFP    L   WM N ++L+++I+  H GIKG+V   + +   P+ KA I +  +          H VT+  +GDY+RLL+PG Y+V A+APG+      V V       A+ +  RL+
Sbjct:   26 DFKHHRYEEMVRALFAVQNECPYITRIY-----SIGQSVEGRHLYVLEFSDNPGIHEALEPEFKYVGNMHGNEVLGRELLIKLAQFLCEEYQARNQRITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNAREIDLNRNFPDLNALMYY-YEKNNGRNHHLPLPDNWEQQVEPETLAVIKWMQSYNFVLSANLHGGAVVANYPFDKSRYPRIRGRTTHADTPDDKLFRKLARTYSYAHSWMHKGWNC---GDFF-DEGITNGASWYSLSKGMQDFNYLYTNCFEITLELSCNKFPPESTLPGEWMANREALVSYIEQVHHGIKGMVYDENNN---PIRKAEISVAGIN---------HDVTSGVDGDYFRLLLPGTYTVTASAPGYLPSTSTVTVG-----PAEAIQVRLQ 416          

Query:  107 EYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELER-ETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPN--SDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRL----EPADSQN---EVKTNNPLCNEIANELKQFKI 1423
            E+RHHN  ++   L + + K  SITHL+      + ++V N  LYV+    +P  H  G PEFKYVGNMHGNEVVGRELLL L +YLC  +    E V  ++ +TRIHI+PSMNPDG+++A     +   GR N+NN DLNRNFPD                     + +D  E  + ET  V+ W+  +PFVLSAN+HGG +V NYP+D    DG ++ S +PD+ VF+ L+ +YS+ NP M      C +  S+ + +DGITNGA+WYS+ GGMQD+NY+ TNCFE+T+E+ C K+P    L  +W  NY++L+ FI   H G+KG V    +            I N T +  VE I H++TTA  GDY+RLLVPG YSV A+A G+K      ++   S+  A++++FRL    +  + Q       T NP   E+ + +K+  +
Sbjct:  482 EFRHHNYADMDLFLRKYSSKFPSITHLH-----SIGRSVENRELYVMVISDNPKVHEHGEPEFKYVGNMHGNEVVGRELLLNLIEYLCLNYGTDPE-VTELLNNTRIHIMPSMNPDGYEVAREGDVQGYKGRNNSNNFDLNRNFPD---------------------QFVDITEPRQPETTAVMNWLKMVPFVLSANLHGGSLVVNYPFDDD-ADGSSRYSKSPDDAVFQQLSRAYSQENPLM-HNGHPCKDLYSEDVFQDGITNGAQWYSVPGGMQDWNYVNTNCFEVTIELSCVKYPMAGDLPQYWEQNYRALLQFIHQVHTGVKGTVSDIGDG---------TGIPNATIS--VEGIKHNITTAHAGDYWRLLVPGTYSVTASAHGYKP---VTILATVSKDRAEIVDFRLTRLYQDGNGQTPSGPYPTQNPSEKELQSLIKELSL 887          

Query:  113 RHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVG----RTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQ-ASLTPDNEVFKFLALSYSKYNPRMFKRKDSCP-NSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFL-----YDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQ-IQCVLVTNESQFSAKVLNFRLEP 1345
            +++N IEL   L+++  +  +I +L       + ++V    L+V+     PD+  PG P+FKYVGNMHG+E V R++L++L +YL  ++   +  V  +V ST I+I+PSMNPDG++   R+R     G    R NA N DLNR+FPD                      T  + E   E + VI WI    FVLS N+HGG VVA+YP+D S    +    S + D+ +F++LAL+YS+ +P M   K +CP +S    +DGITNGA+WY + GGMQD+NY+  NC EIT+E+ C K P    L       F+  N KS     Q  HIG++G V          V+ A +   ++  AG    I H++TTA  GDYYRLL+PG Y++ A A G  S+ I+ V V    +  A  LNF L P
Sbjct:   41 KYYNYIELTERLQQLARRYPTIAYL-----SSIGQSVEGRELWVMRVTVDPDKETPGKPKFKYVGNMHGDETVSRQVLVYLVEYLLARY-GEDPRVTALVNSTDIYIMPSMNPDGFE---RSREGDCAGDHGGRNNARNKDLNRSFPDQ------------------YDGTSTDAETVPEVMAVIRWIQEKKFVLSGNLHGGTVVASYPFDDSAKHQRQGFYSQSADDALFRYLALAYSQKHPVMKTGKPNCPEDSSETFEDGITNGAQWYDVPGGMQDYNYIYGNCLEITMELSCCKHPPTNELPYMEKVQFYPNNRKSNFAVFQV-HIGVQGFVT-------DAVSGAPLSDVSIVVAG----IRHNLTTAKYGDYYRLLLPGTYNITAVAAGHLSKTIRNVQVI---EGEATKLNFTLAP 421          

Query:   80 LVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPN-SDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLE 1342
            LV  ++    +R+ +  +L   L+ +      IT L+ L      ++V    ++ +     P    P  P  ++V  +HGN  VG E+LL  A +LC  +   N  +  ++ STRI I+PS+NPDG + A   +     G+ NAN  DL+ +F       F N+          +++ +   E + ET  ++ +I +  F LS  + GG +V  YPYDK     + + +L       K+LA  Y+  +P+M      C N +  +  DG+   A+  S  G M+DF+    NC EIT+  GC  FP    L   W  N K+L++ +   H G++G+V  R + G KP+  A+I I               V +   G ++ LL PG + + A A G++ +   V+V+  S  +A+ L F  +
Sbjct:  894 LVSSSATDSSFRYRSFRDLSAFLKGLTLNFPKITILHRL-----GQSVEFRNIFALEISNKPTEPEPSEPNIRFVAGIHGNAPVGTEMLLEFAAFLCINY-GKNPAITKLINSTRIFIVPSVNPDGREQAVEKQCTSAQGKNNANGKDLDTDF-------FGNA----------SQRVV---EPQPETKSMMNFIMNNKFTLSVALDGGSLVVTYPYDKPVQTVEKEGTL-------KYLASVYANNHPKMHLGDTGCSNNAQGIVPDGVILAAERQSHMGSMKDFSMDFGNCPEITVYTGCCFFPPADQLSTLWAENKKALLSMLVEVHKGVRGVV--RDKKG-KPIVGAIIVINGG----------RRVYSTEGGYFHALLAPGSHDIEAVADGYQQKHLKVVVS--SYEAARFLLFEFD 1267          

Query:   47 MNKYLCLIFVFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNNPLCNEIANELKQFKIVRSEKDMLVKEMKGDPAI 1477
            MNKYLCLIFVFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELG KQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIK+TNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNNPLCNEIANELKQFKIVRSEKDMLVKEMKGDPAI
Sbjct:    1 MNKYLCLIFVFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGGKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKVTNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRLEPADSQNEVKTNNPLCNEIANELKQFKIVRSEKDMLVKEMKGDPAI 477          

Query:   68 IFVFLVLEASGKIEY----RHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRK--QDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEP--ILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRL 1339
            I V L+L ++  +      + H+N EL +I+ +I+ KC +IT +YYL+ GD+DKT+ +NRLYV  FGK P RH  GIPEF ++ N+HGNE++GRE  + +ADYLC++++  +E++  ++ S RIH L SMNPDG+ +       +  G  N    DLN +FPDL    FK  E       DHL  +K   E + +RETLM + W+ ++P+VL  N+H   +V NY Y +S    K   + TPD+ +++++   +   +P M + +  CP       + +  G+ W S+  G  DF+YL+TN     L + C++      +   W  +  SL+ + +  H+G+KG+V  R E G + +  AVIK  N+T +   EP  I+  + T   GDYYR+L+PG Y+++ +  G+K  I+C  V N  +FSAKV++F L
Sbjct:    5 ILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG-FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNVTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVV--RDEEGNR-IVNAVIKTVNLTDS---EPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 429          

Query:  152 RINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRK--QDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEP--ILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRL 1339
            +I+ KC +IT +YYL+ GD+DKT+ +NRLYV  FGK P RH  GIPEF ++ N+HGNE++GRE  + +ADYLC++++  +E++  ++ S RIH L SMNPDG+ +       +  G  N    DLN +FPDL    FK  E       DHL  +K   E + +RETLM + W+ ++P+VL  N+H   +V NY Y +S    K   + TPD+ +++++   +   +P M + +  CP       + +  G+ W S+  G  DF+YL+TN     L + C++      +   W  +  SL+ + +  H+G+KG+V  R E G + +  AVIK  N+T +   EP  I+  + T   GDYYR+L+PG Y+++ +  G+K  I+C  V N  +FSAKV++F L
Sbjct:    3 KIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG-FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNVTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVV--RDEEGNR-IVNAVIKTVNLTDS---EPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 395          

Query:  113 RHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSELGRKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKN----QASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKITNVTAAGQVEPILHHVTTASEGDYYRLLVPGRYSV 1246
            ++H  +EL N L+ I+    +IT LY      +  +V  N L+V+   K P  HIPG+PEFKY+GNMHGNEVVGRELL+ L +  C  +   N+ + + + +TRIHI+P+MNPDG++ +         GR+N NN DLNRNFPD  K                     ++ +LE ET  V+ WI    FVLSAN HGG +VANYP+D       N    + S +PD+++F  LA SYS  +  M K    CP       +GITNGAKWYS++GGMQD+NY+ +NCFEIT+EV C+K+P    L  +W  N  SL+NF+   H+G+KG V        +P++ A I          V+ I HH+ TA +GDY+RLL PG+YSV
Sbjct:   17 KYHTQVELTNFLKNIHSLYPTITRLY-----SIGNSVSGNPLWVMEISKKPGFHIPGVPEFKYIGNMHGNEVVGRELLIGLIELFCVNY-GKNDLLTSFINNTRIHIMPTMNPDGFKKSREGDFNGEFGRSNMNNKDLNRNFPDQFKK--------------------NDKQLEPETKAVMNWIRQYSFVLSANFHGGSLVANYPFDNYQSTNANAMQIRYSASPDDKLFIQLAKSYSMAHQNM-KIGGPCPGETEQFPNGITNGAKWYSVNGGMQDWNYMNSNCFEITVEVSCKKYPLKSELNRYWNQNKYSLINFMAQVHMGLKGFV--HDTISQRPISNATI---------NVKGINHHIFTAIDGDYWRLLTPGKYSV 360          

Query:   74 VFLVLEASGKIEYRHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNAN-----NVDLNRNFP 541
            +F    +S  I Y  +  IE     E I +K   + +  +++ G+   T  N +L+++   K+       +P     G +H  E +     LF+ D L     +   W   I+   + +++P +NPDG++ ++ T   W   R+         VD+NRNFP
Sbjct:  118 LFRTGSSSDHIAYLRYQQIE-----EWIKEKVQGVNYAKFVKFGE---TYENRKLFMVKLSKND-----SLPIVWLDGGIHAREWIATSSALFIIDKLLRN--SSETW--EILSKYQFYVVPLVNPDGYEYSHETHRLWRKNRSRFTFSKCIGVDMNRNFP 261