GPI mannosyltransferase 1

Overview
NameGPI mannosyltransferase 1
Smed IDSMED30031698
Length (bp)1187
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GPI mannosyltransferase 1 (SMED30031698) t-SNE clustered cells

Violin plots show distribution of expression levels for GPI mannosyltransferase 1 (SMED30031698) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GPI mannosyltransferase 1 (SMED30031698) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GPI mannosyltransferase 1 (SMED30031698) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031698

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
tail regionSMED30031698SMESG000029206.1 SmedASXL_067167SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parenchymaSMED30031698SMESG000029206.1 dd_Smed_v4_13168_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Human
Match: PIGM (phosphatidylinositol glycan anchor biosynthesis class M [Source:HGNC Symbol;Acc:HGNC:18858])

HSP 1 Score: 230.72 bits (587), Expect = 3.139e-71
Identity = 145/384 (37.76%), Postives = 218/384 (56.77%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLK--TNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQIL-----------------IPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASI-ILLISHAVQIRLMSQLFAKELDKN 1167
             D    V+YTDIDY VFT ++ F+    SPYL  TYRY+PL+ +LL PN Y  + FGKFLF  CDL+ + ++Y +   + L       YC+  FWL NPL   VSSRGN ++ +  L+L  LY +    +  + + +   +H+K+YP+ Y   I  +L       + L                 + NR    F     L+F  +S  F+  YGW+F++++Y YH  R DI+HNFS YFY LYL + +K    + IAAF+PQL+LL  +S+ + + L+  C L T  FV FNKV TSQYF+W++  LP  M  V +   R+V++   +WF+ Q +WL  AY LEF+G+  FL +W+A +  LLI+ ++ I+++S    + L + 
Sbjct:   39 QDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCV--FWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL-LMLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEEPLTER 419
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Celegans
Match: B0491.1 (GPI mannosyltransferase 1 [Source:UniProtKB/TrEMBL;Acc:Q17515])

HSP 1 Score: 198.364 bits (503), Expect = 3.470e-59
Identity = 129/367 (35.15%), Postives = 208/367 (56.68%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLI----------DRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILF-SLCIHLKLYPIIYSFSIFFYL-------CKTDRFPQILIPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTK-LCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLIS-YCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLISHA 1116
            HD  + V +TDIDY+VF+ ++  + +  SP+   TYRY+P +A++LLP  +F   FGK LFC+ D++ +++ + I          + R ++K +    +  +WL NPL   +S+RGN E+ +  ++L  +  L       + ++  +L I LK+YP+IY  S+F  L       C  ++F   L+ N   F + +  L SF  +   FF +YG  F+    +YH  R D+ HNFS YFY LYL      + ++I + AFIPQ++L+ F ++KH   L     + T AFV +NKV TSQYF+W++  LP     + +S  R + +S    WF +QGIWL AAY  EF+G   F ++++AS + LI+++
Sbjct:   36 HDYLFKVNFTDIDYHVFSDAAKHVSNGGSPFDRATYRYTPALAWILLPVVHF-PDFGKILFCIFDILVAILYFKIMEKDLNETKSETREEMKDDQTMNVVIYWLANPLTAIISARGNAESIVAAVVLLNIVLLQKGYWKSAALVHGALAIQLKIYPLIYLPSVFLSLSTIGEQSCVVNKFKS-LVSNWKGFAYMLVTLTSFAAVVLFFFQIYGQLFLDEYLIYHVKRRDLAHNFSPYFYLLYLYEANPTMSQIIGLGAFIPQIVLIVFFAFKHYDDLPFCWFITTFAFVTYNKVCTSQYFVWYIVLLPLLAHKIMMS--RQLALSLMAAWFATQGIWLLAAYLFEFQGWNTFFLMFLASCLFLIANS 398
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Fly
Match: PIG-M (gene:FBgn0034649 transcript:FBtr0071680)

HSP 1 Score: 142.895 bits (359), Expect = 5.816e-38
Identity = 108/344 (31.40%), Postives = 166/344 (48.26%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLI--------------------------DR------RRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQ---------ICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQ--------ILIPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCK---LISIAAFIPQLLLLCFLS---WKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLP 942
            HDS   V YTDIDY V T  +  + +  +P+   TYRYSP++AYL   N     ++GK L+   DL+ + ++Y +                          D+       R    N+    + FWLYNPL   +S+RG+ + F    ++ T+Y LL ++         I  +G+   L IHL+LYP++  FS+ +YL  + R  Q        IL PN+         L+S +  +  F+ +YGW++I  +YLYHF R D +HNFS+ F   YL S + + +   ++      PQ LL+ +LS    + RQ L           V +N V TSQYF+W++  LP
Sbjct:   44 HDSQSAVPYTDIDYKVVTDGARQVLAGDTPFARHTYRYSPIMAYLQTFNILLHPAWGKLLYATFDLLIATLIYRLVHMEIKSQYQKTVQHLLSKFNRPRDSDQSLDALDERSHPENLARASACFWLYNPLTAVISTRGSGDCFSSFFVILTIYLLLKSEHNVTRSYWLIFGAGLAHGLVIHLRLYPLL--FSLAYYLSLSTRLTQTPLDFLCQILRPNKQQLCLISGTLISLVAFTWTFYTMYGWEYIYEAYLYHFVRKDPRHNFSLQFLLQYLGSASSVAEPSAILKTLVLAPQFLLILYLSLSFGQFRQTLPFCIFAVAFVIVTYNSVVTSQYFIWYLAILP 385
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Fly
Match: PIG-M (gene:FBgn0034649 transcript:FBtr0071681)

HSP 1 Score: 142.895 bits (359), Expect = 5.816e-38
Identity = 108/344 (31.40%), Postives = 166/344 (48.26%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLI--------------------------DR------RRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQ---------ICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQ--------ILIPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCK---LISIAAFIPQLLLLCFLS---WKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLP 942
            HDS   V YTDIDY V T  +  + +  +P+   TYRYSP++AYL   N     ++GK L+   DL+ + ++Y +                          D+       R    N+    + FWLYNPL   +S+RG+ + F    ++ T+Y LL ++         I  +G+   L IHL+LYP++  FS+ +YL  + R  Q        IL PN+         L+S +  +  F+ +YGW++I  +YLYHF R D +HNFS+ F   YL S + + +   ++      PQ LL+ +LS    + RQ L           V +N V TSQYF+W++  LP
Sbjct:   44 HDSQSAVPYTDIDYKVVTDGARQVLAGDTPFARHTYRYSPIMAYLQTFNILLHPAWGKLLYATFDLLIATLIYRLVHMEIKSQYQKTVQHLLSKFNRPRDSDQSLDALDERSHPENLARASACFWLYNPLTAVISTRGSGDCFSSFFVILTIYLLLKSEHNVTRSYWLIFGAGLAHGLVIHLRLYPLL--FSLAYYLSLSTRLTQTPLDFLCQILRPNKQQLCLISGTLISLVAFTWTFYTMYGWEYIYEAYLYHFVRKDPRHNFSLQFLLQYLGSASSVAEPSAILKTLVLAPQFLLILYLSLSFGQFRQTLPFCIFAVAFVIVTYNSVVTSQYFIWYLAILP 385
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Zebrafish
Match: pigm (phosphatidylinositol glycan anchor biosynthesis, class M [Source:NCBI gene;Acc:393361])

HSP 1 Score: 165.236 bits (417), Expect = 1.067e-46
Identity = 135/351 (38.46%), Postives = 197/351 (56.13%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCIS-AFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTD-RFPQILIP--NRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLISH 1113
            + D    +KYTD+DY+VFT ++ FI    SPY   T+RY+PL+A LL+PN Y    FGK LF  CDL+  L+M+ +   R   ++   C+S   WL NPL   VS+RGN E+ L VL+LSTL  L L +   + +LF L +H+K+YP+ Y+  I   L     R   +L+   +    +FA      FL +  +F+  YGW+F+Q +YLYH  R D++HNFS +FY  Y+ +       +     +PQLLLL   S      L   C L T  FV+FN+V TSQYF+W++  L   +       L   L+   +W + QG+WL  AY LEF+G   F  +W AS++ L+++
Sbjct:   25 YQDQTLKLKYTDVDYHVFTDAARFITQGESPYRRSTFRYTPLLALLLVPNVYLSLLFGKLLFGFCDLLSGLLMFRLLVLRG-ASHGSACVSCGLWLLNPLPMAVSTRGNAESVLAVLVLSTLLCLQLRKHTTAALLFGLSVHMKIYPVTYALPIALALTAAPARGRGVLLRFFSPALLRFAAVSAAVFLSLGLIFYCRYGWEFLQEAYLYHLTRRDLRHNFSPFFYLQYVCAERCWSSGLLPLLLLPQLLLLLLASAAFSSDLPFCCFLHTAVFVSFNRVCTSQYFLWYLCLL-PVVLPRLRLRLGRGLLLLLLWLLLQGLWLAPAYLLEFQGWNSFSWIWAASLLFLLTN 373
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Xenopus
Match: g6pc.2 (glucose-6-phosphatase, catalytic subunit, gene 2 [Source:Xenbase;Acc:XB-GENE-5765474])

HSP 1 Score: 204.527 bits (519), Expect = 4.025e-61
Identity = 130/338 (38.46%), Postives = 197/338 (58.28%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMY--LIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTD----RFPQILIPN----------------RNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQG 1020
            + D    VKYTD+DY+VFT ++ ++   +SPY   TYRY+PL+A++L PN Y  + +GK LF  CDL+ + +++  L+DR  K   ++ YC  A WL+NPL   VSSRGN E+ L VL+LS LY +   ++    +++ L +H+K+YPI Y   I  +  K D    +  + ++ N                R+   F     ++F L++  F+  YGW+F++N+YLYH  R DI+HNFS YFY LYL +      ++ +AAF PQL+LL  +S  + + L   C L T  FV+FNKV TSQYF+W++  LP  M  + +S    + +   +WF SQG
Sbjct:   34 YQDQTMLVKYTDVDYHVFTDAAEYLTQGVSPYKRATYRYTPLLAWILTPNIYVTELYGKMLFVCCDLLAAYLIHRILVDRGIKDSASL-YC--AIWLFNPLPMVVSSRGNAESVLAVLVLSVLYYVQKRRLIKGALIYGLSVHMKIYPITYILPIALFFQKEDFYGSQEGKRVVSNLKYIRIFRNLLQRLLSRDILLFVTVSGVTFALLTLFFYYRYGWEFLENTYLYHLTRRDIRHNFSPYFYMLYLTAENNNSFILGLAAFFPQLVLLFVVSLAYFKDLPFCCFLHTAIFVSFNKVCTSQYFLWYLCLLPLVMPGLKMSMTNGICL-IILWFFSQG 367
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Mouse
Match: Pigm (phosphatidylinositol glycan anchor biosynthesis, class M [Source:MGI Symbol;Acc:MGI:1914806])

HSP 1 Score: 229.18 bits (583), Expect = 9.423e-71
Identity = 146/384 (38.02%), Postives = 218/384 (56.77%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLK--TNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQILIPNRNHFKX-----------------XXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASI-ILLISHAVQIRLMSQLFAKELDKN 1167
             D    V+YTDIDY+VFT ++ F+    SPYL  TYRY+PL+++LL PN Y  + FGKFLF  CDL+ + ++Y +   + L       YC+  FWL NPL   VSSRGN ++ +  L+LSTLY +    I  + + +   +H+K+YP+ Y   I  +L       + L   R  F+                       L+F+ +S  F+  YGW+F++++Y YH  R DI+HNFS YFY LYL + +K    + IAAF+PQ +LL   S+ + + L+  C L T  FV FNKV TSQYF+W++  LP  M  V +   R+V++    WF+ Q +WL  AY LEF+G+  FL +W+A +  LLI+ ++ I+++S      L + 
Sbjct:   39 QDRTLLVRYTDIDYHVFTDAARFVTEGRSPYLRATYRYTPLLSWLLTPNVYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCV--FWLLNPLPMAVSSRGNADSIVASLVLSTLYFIEKRLIACAAVFYGFAVHMKMYPVTYILPIALHLRPERDDDERLRQARFSFQARLYDFLRRLCSWAVLLFVAVAGLTFVALSFGFYYKYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFTLGIAAFLPQFILLSAASFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL-LLFWFIGQALWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEDRLTER 419
[Close]
BLAST of GPI mannosyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q66IJ4|PIGM_XENTR (GPI mannosyltransferase 1 OS=Xenopus tropicalis OX=8364 GN=pigm PE=2 SV=1)

HSP 1 Score: 237.654 bits (605), Expect = 3.067e-73
Identity = 152/390 (38.97%), Postives = 231/390 (59.23%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMY--LIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTD--------------RFPQIL------IPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASII-LLISHAVQIRLMS--QLFAKELDKN 1167
            + D    VKYTD+DY+VFT ++ ++   +SPY   TYRY+PL+A++L PN Y  + +GK LF  CDL+ + +++  L+DR  K   ++ YC  A WL+NPL   VSSRGN E+ L VL+LS LY +   ++    +++ L +H+K+YPI Y   I  +  K D              ++ +I       + +R+   F     ++F L++  F+  YGW+F++N+YLYH  R DI+HNFS YFY LYL +      ++ +AAF PQL+LL  +S  + + L   C L T  FV+FNKV TSQYF+W++  LP  M  + +S    + +   +WF SQ IWL  AY LEFEGQ  FL +W A ++ LLI+  + ++++S  QL +K+  K 
Sbjct:   34 YQDQTMLVKYTDVDYHVFTDAAEYLTQGVSPYKRATYRYTPLLAWILTPNIYVTELYGKMLFVCCDLLAAYLIHRILVDRGIKDSASL-YC--AIWLFNPLPMVVSSRGNAESVLAVLVLSVLYYVQKRRLIKGALIYGLSVHMKIYPITYILPIALFFQKEDFYGSQEGKRVVSNLKYIRIFRNLLQRLLSRDILLFVTVSGVTFALLTLFFYYRYGWEFLENTYLYHLTRRDIRHNFSPYFYMLYLTAENNNSFILGLAAFFPQLVLLFVVSLAYFKDLPFCCFLHTAIFVSFNKVCTSQYFLWYLCLLPLVMPGLKMSMTNGICL-IILWFFSQAIWLVPAYFLEFEGQNTFLYIWCAGLLFLLINTVIIVQIISNYQLQSKKTKKT 419
[Close]
BLAST of GPI mannosyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q4R4E1|PIGM_MACFA (GPI mannosyltransferase 1 OS=Macaca fascicularis OX=9541 GN=PIGM PE=2 SV=1)

HSP 1 Score: 234.958 bits (598), Expect = 3.529e-72
Identity = 144/388 (37.11%), Postives = 219/388 (56.44%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLI------DRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQILIPNRNHFKX-----------------XXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASI-ILLISHAVQIRLMSQLFAKELDKN 1167
             D    V+YTDIDY VFT ++ F+    SPYL  TYRY+PL+ +LL PN Y  + FGKFLF  CDL+ + ++Y +       RR+       YC+  FWL NPL   VSSRGN ++ +  L+L  LY +    +  + + +   +H+K+YP+ Y   I  +L       + L  +R  F+                       L+F  +S  F+  YGW+F++++Y YH  R DI+HNFS YFY LYL + +K    + IAAF+PQ +LL  +S+ + + L+  C L T  FV FNKV TSQYF+W++  LP  M  V ++  R+V++   +WF+ Q +WL  AY LEF+G+  FL +W+A +  LLI+ ++ I+++S    + L + 
Sbjct:   39 QDRTLHVRYTDIDYQVFTDAARFVAEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLARRQACG----YCV--FWLLNPLPMAVSSRGNADSIVASLVLMVLYLIRKRVVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQSRYTFQAHLYELLKRLCDRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQFILLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMTWKRAVVL-LMLWFIGQALWLAPAYVLEFQGKNTFLFIWLAGLFFLLINSSILIQIISHYKEEPLTER 419
[Close]
BLAST of GPI mannosyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q9EQY6|PIGM_RAT (GPI mannosyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Pigm PE=2 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 9.121e-71
Identity = 147/384 (38.28%), Postives = 220/384 (57.29%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLK--TNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQILIPNRNHFKX-----------------XXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASI-ILLISHAVQIRLMSQLFAKELDKN 1167
             D    V+YTDIDY+VFT ++ F+    SPYL  TYRY+PL+++LL PN Y  + FGKFLF  CDL+ + ++Y +   + L       YC+  FWL NPL   VSSRGN ++ +  L+L+TLY +    I  + + +   +H+K+YP+ Y   I  +L       + L   R  F+                       L+FL +S  F+  YGW+F++++YLYH  R DI+HNFS YFY LYL + +K    + IAAF+PQ +LL   S+ + + L+  C L T  FV FNKV TSQYF+W++  LP  M  V +   R+V++   +WF+ Q +WL  AY LEF+G+  FL +W+A +  LLI+ ++ I+++S      L + 
Sbjct:   39 QDRTLLVRYTDIDYHVFTDAARFVTEGRSPYLRATYRYTPLLSWLLTPNVYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCV--FWLLNPLPMAVSSRGNADSIVASLVLTTLYLIEKRLIACAAVFYGFAVHMKMYPVTYILPIALHLRPERDSDEGLRLARYSFQARLYDFLKRLCSWAVLLFVAIAGLTFLALSFGFYYKYGWEFLEHTYLYHLTRRDIRHNFSPYFYMLYLTAESKWSFTLGIAAFLPQFILLSAASFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL-LMLWFIGQALWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEDRLTER 419
[Close]
BLAST of GPI mannosyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q5RAH7|PIGM_PONAB (GPI mannosyltransferase 1 OS=Pongo abelii OX=9601 GN=PIGM PE=2 SV=1)

HSP 1 Score: 230.72 bits (587), Expect = 1.508e-70
Identity = 145/384 (37.76%), Postives = 218/384 (56.77%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLK--TNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQIL-----------------IPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASI-ILLISHAVQIRLMSQLFAKELDKN 1167
             D    V+YTDIDY VFT ++ F+    SPYL  TYRY+PL+ +LL PN Y  + FGKFLF  CDL+ + ++Y +   + L       YC+  FWL NPL   VSSRGN ++ +  L+L  LY +    +  + + +   +H+K+YP+ Y   I  +L       + L                 + NR    F     L+F  +S  F+  YGW+F++++Y YH  R DI+HNFS YFY LYL + +K    + IAAF+PQL+LL  +S+ + + L+  C L T  FV FNKV TSQYF+W++  LP  M  V +   R+V++   +WF+ Q +WL  AY LEF+G+  FL +W+A +  LLI+ ++ I+++S    + L + 
Sbjct:   39 QDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCV--FWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL-LMLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEEPLTER 419
[Close]
BLAST of GPI mannosyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q9H3S5|PIGM_HUMAN (GPI mannosyltransferase 1 OS=Homo sapiens OX=9606 GN=PIGM PE=1 SV=1)

HSP 1 Score: 230.72 bits (587), Expect = 1.508e-70
Identity = 145/384 (37.76%), Postives = 218/384 (56.77%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLK--TNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQIL-----------------IPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASI-ILLISHAVQIRLMSQLFAKELDKN 1167
             D    V+YTDIDY VFT ++ F+    SPYL  TYRY+PL+ +LL PN Y  + FGKFLF  CDL+ + ++Y +   + L       YC+  FWL NPL   VSSRGN ++ +  L+L  LY +    +  + + +   +H+K+YP+ Y   I  +L       + L                 + NR    F     L+F  +S  F+  YGW+F++++Y YH  R DI+HNFS YFY LYL + +K    + IAAF+PQL+LL  +S+ + + L+  C L T  FV FNKV TSQYF+W++  LP  M  V +   R+V++   +WF+ Q +WL  AY LEF+G+  FL +W+A +  LLI+ ++ I+++S    + L + 
Sbjct:   39 QDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCV--FWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL-LMLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEEPLTER 419
[Close]
BLAST of GPI mannosyltransferase 1 vs. TrEMBL
Match: A0A2U9CY02 (GPI mannosyltransferase 1 OS=Scophthalmus maximus OX=52904 GN=SMAX5B_001776 PE=3 SV=1)

HSP 1 Score: 263.848 bits (673), Expect = 5.432e-81
Identity = 146/357 (40.90%), Postives = 208/357 (58.26%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQILIPNRNHFKXXXXXXXXXXXXXXXXXX-------------XYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLI 1107
             D   +VKYTD+DY+VFT ++  +    SPY   TYRY+PL+A+LL PN Y   +FGK LF VCD++  L++Y I R R L +     +S+ WL NPL   VSSRGN E+ L  L+L TL  +   ++  + +L+ L +H+K+YP+ Y+  I   L   +  P+   P    F       ++  L+                   +YGW+F+  +YLYH  R DIKHNFS YFY LYL + ++  + + +AAF+PQL+LL   SW  R  L  SC L T  FV+FNKV TSQYF+W++  LP  +  ++LS  + V +   +WF  QGIWL  AY LEFEG   FL++W+A ++ LI
Sbjct:   32 QDRTMSVKYTDVDYHVFTDAAGLVAEGGSPYNRSTYRYTPLLAWLLTPNIYLCTAFGKILFVVCDVLSGLLIYRILRLRGLTSETARRVSSLWLLNPLPMGVSSRGNAESILAALVLGTLLCMQGQRLTWAAVLYGLSVHMKIYPVTYALPIALTLRSPETRPEEGKPRWRRFIGFTGSFVNAELLLFASVAGGVFFVLTALFYYMYGWEFLHETYLYHLTRRDIKHNFSPYFYMLYLTADSRWSQWLGLAAFLPQLVLLLAASWAFRCDLAFSCFLHTAIFVSFNKVCTSQYFLWYLCLLPLVIPHLSLSLEQGVGL-LLLWFAGQGIWLGPAYFLEFEGYNTFLLIWLAGLLFLI 387
[Close]
BLAST of GPI mannosyltransferase 1 vs. TrEMBL
Match: A0A3B4TM41 (GPI mannosyltransferase 1 OS=Seriola dumerili OX=41447 PE=3 SV=1)

HSP 1 Score: 260.381 bits (664), Expect = 1.156e-79
Identity = 154/357 (43.14%), Postives = 213/357 (59.66%), Query Frame = 1 
Query:   76 HDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTD-----------RFPQILIP--NRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLI 1107
             D    VKYTDIDY+VFT ++ FI    SPY   TYRY+PL+A+LL PN Y    FGK LF +CD++  L++Y I R R L +     +S+ WL NPL   VSSRGN E+ L  L+L TL  +   ++  + IL+ L +H+K+YPI Y+  I   L   +           RF   +    N   F FA      F ++++LF+ +YGW+F+  +YLYH  R DI+HNFS YFY LYL + ++  + + +AAFIPQL+LL   SW     L  SC L T  FV+FNKV TSQYF+W++  LP  +  ++LS  + V +   +WF  QGIWL  AY LEFEG   FL++W+A ++ LI
Sbjct:   32 QDRTMVVKYTDIDYHVFTDAARFITEGESPYNRSTYRYTPLLAWLLTPNIYLSMVFGKILFVLCDVLSGLLIYRILRLRGLDSETARRVSSLWLLNPLPMGVSSRGNAESILAALVLGTLLCMEGRRLIWAAILYGLSVHMKIYPITYALPIALTLRTPETRAERDRQSWRRFIGFIGSFLNAQLFLFASVAGGVFCVLTALFYYMYGWEFLHETYLYHLTRRDIRHNFSPYFYMLYLTADSRWSQWLGLAAFIPQLVLLLAASWAFHSDLAFSCFLHTAIFVSFNKVCTSQYFLWYLCLLPLVIPHLSLSLKQGVGL-LLLWFAGQGIWLGPAYFLEFEGYNTFLLIWLAGLLFLI 387
[Close]
BLAST of GPI mannosyltransferase 1 vs. TrEMBL
Match: A0A4V6ATC6 (GPI mannosyltransferase 1 OS=Collichthys lucidus OX=240159 GN=D9C73_022146 PE=3 SV=1)

HSP 1 Score: 258.84 bits (660), Expect = 5.068e-79
Identity = 152/358 (42.46%), Postives = 212/358 (59.22%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQIL-------------IPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLI 1107
            + D    VKYTDIDY+VFT ++ FI    SPY   TYRY+PL+A++L PN +    FGK LF VCD++  L++Y I R R L +     + A WL NPL   VSSRGN E+ L  L+L TL  +    +  + +L+ L +H+K+YPI Y+  I   L +T R   I                NR  F FA      F ++++LF+ +YGW+F+  +YLYH  R DI+HNFS YFY LYL + ++  + + +AAF+PQL+LL   SW     L   C L T  FV+FNKV TSQYF+W++  LP  +  ++LS  + V +   +WF  QGIWL  AY LEFEG   FL++W+A ++ LI
Sbjct:   31 YQDRTMVVKYTDIDYHVFTDAARFITEGESPYNRSTYRYTPLLAWMLTPNIHLSMMFGKILFIVCDVMSGLLIYRILRLRGLNSETAQRVCALWLLNPLPMGVSSRGNAESILAALVLGTLLCMEAQHLIWAAVLYGLSVHMKIYPITYALPIALAL-RTTRSEDIKRWRWRSFIGFMGSFLNRELFLFASVAGGVFCMLTALFYYMYGWEFLHETYLYHLTRRDIRHNFSPYFYMLYLTADSRWSQWLGLAAFLPQLILLLVASWAFHSDLPFCCFLHTAVFVSFNKVCTSQYFLWYLCLLPLIIPHLSLSVKQGVGL-LILWFTGQGIWLGPAYFLEFEGYNTFLLIWLAGLLFLI 386
[Close]
BLAST of GPI mannosyltransferase 1 vs. TrEMBL
Match: A0A4U5VIR6 (GPI mannosyltransferase 1 OS=Collichthys lucidus OX=240159 GN=D9C73_022143 PE=3 SV=1)

HSP 1 Score: 258.455 bits (659), Expect = 6.561e-79
Identity = 153/358 (42.74%), Postives = 212/358 (59.22%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQIL-------------IPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLI 1107
            + D    VKYTDIDY+VFT ++ FI    SPY   TYRY+PL+A++L PN +    FGK LF VCD++  L++Y I R R L +     + A WL NPL   VSSRGN E+ L  L+L TL  +    +  + +L+ L +H+K+YPI Y+  I   L +T R   I                NR  F FA      F ++++LFF +YGW+F+  +YLYH  R DI+HNFS YFY LYL + ++  + + +AAF+PQL+LL   SW     L   C L T  FV+FNKV TSQYF+W++  LP  +  ++LS  + V +   +WF  QGIWL  AY LEFEG   FL++W+A ++ LI
Sbjct:   31 YQDRTMVVKYTDIDYHVFTDAARFITEGESPYNRSTYRYTPLLAWMLTPNIHLSMMFGKILFIVCDVMSGLLIYRILRLRGLNSETARRVCALWLLNPLPMGVSSRGNAESILAALVLGTLLCMEARHLIWAAVLYGLSVHMKIYPITYALPIALAL-RTTRSEDIKRWRWRSFIGFTGSFLNRELFLFASVAGGVFCMLTALFFYMYGWEFLHETYLYHLTRRDIRHNFSPYFYMLYLTADSRWSQWLGLAAFLPQLILLLVASWAFHSDLPFCCFLHTAVFVSFNKVCTSQYFLWYLCLLPLIIPHLSLSVKQGVGL-LILWFTGQGIWLGPAYFLEFEGYNTFLLIWLAGLLFLI 386
[Close]
BLAST of GPI mannosyltransferase 1 vs. TrEMBL
Match: A0A060WQB7 (GPI mannosyltransferase 1 OS=Oncorhynchus mykiss OX=8022 GN=GSONMT00048552001 PE=3 SV=1)

HSP 1 Score: 258.07 bits (658), Expect = 9.947e-79
Identity = 155/359 (43.18%), Postives = 214/359 (59.61%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDR--------------FPQILIPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLI 1107
            + D    VKYTD+DY+VFT +S FI    SPY   TYRY+PL+A++L PN Y    FGK LF  CD++   ++YLI R+R L       + + WL NPL   VSSRGN E+ L  L+L+TL  L L Q+ ++ IL+ L +H+K+YP+ Y+  I   L + +               FP  L+ N+  F FA    + F  ++ LF+N+YGWDF+Q +YLYH  R DI+HNFS YFY LYL + +     + +AAF+PQ LLL  +S      L   C L T  FV+FNKV TSQYF+W++   P  +  +TLS  + V +   +WF  QGIWL  AY LEFEG   FL++W+A ++ LI
Sbjct:   31 YQDRTMVVKYTDVDYHVFTDASKFITQGQSPYHRSTYRYTPLLAWILTPNVYLSHVFGKLLFITCDVLSGHLIYLILRQRGLSCKAACRVCSLWLLNPLPAGVSSRGNAESVLTALVLATLLCLELRQLPMAAILYGLAVHMKIYPVTYALPIALSLQRKENVEERGVGWWRRALGFPLRLL-NKELFLFAGVAGVVFCGLTVLFYNMYGWDFLQETYLYHLTRRDIRHNFSPYFYMLYLTADSPWSLALGLAAFLPQALLLFLVSLAFHTDLAFCCFLHTAIFVSFNKVCTSQYFLWYLCLFPLVLPRLTLSPKQGVEL-LALWFAGQGIWLAPAYYLEFEGYNTFLLIWLAGLMFLI 387
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Cavefish
Match: pigm (phosphatidylinositol glycan anchor biosynthesis class M [Source:NCBI gene;Acc:103027410])

HSP 1 Score: 229.95 bits (585), Expect = 2.663e-71
Identity = 146/378 (38.62%), Postives = 220/378 (58.20%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLC-------KTDRFPQIL--IPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASII-LLISHAVQIRLMSQLFAKELDKNKSS 1176
            + D    VKYTDIDY+VFT ++ F+    SPY   TYRY+PL+A++L+PN Y    FGK LF  CD++  +++Y I   + L +N   C SA WL NPL   VS+RG+ EA L +L+LSTL  L L +  ++   ++L +H+K+YP+ Y+  I  Y+        K     +IL  + N+N   FA    + FL ++  F+ +YGWDF+  +YLYH  R DI+HNFS YFY +YL   ++   ++ + +F+PQLLLL   S      L   C L T  FV+FNKV TSQYF+W++  L   +      S++       +WF+ QG+WL  AY LEFEG   F+ +W+A ++ L I+  V ++++S    +   + K +
Sbjct:   35 YQDKTMVVKYTDIDYHVFTDAARFVTQGESPYNRSTYRYTPLLAWILVPNIYVTPHFGKLLFVTCDVLSGVLLYRILSLQGLSSNAAGCFSAVWLLNPLPIGVSTRGSAEAVLSLLVLSTLLCLELKRRFMAAFFYALSVHMKIYPVTYALPIALYISSRGSLEGKGRSLFRILRGLFNKNVVMFAAVAGVVFLALTIAFYYMYGWDFLHETYLYHLTRRDIRHNFSPYFYMMYLSVESEWSLVLGLVSFLPQLLLLLLTSVAFYADLPFCCFLNTAIFVSFNKVCTSQYFLWYLCLL-PLVLPRLRLSIKQGAGLLLLWFIGQGLWLMPAYYLEFEGHNTFVYIWLAGLLFLFINSFVMVQIISHYTPRTFHQTKKT 411
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Yeast
Match: GPI14 (Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M [Source:SGD;Acc:S000003774])

HSP 1 Score: 194.512 bits (493), Expect = 1.060e-58
Identity = 133/364 (36.54%), Postives = 209/364 (57.42%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQ-SFGKFLFCVCDLICSLIM-----YLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLK--LYPIIYSFSIFFYLCKTDRFPQILIPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIA--AFIPQLLLL----CFLSWKHR-QRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLI-VWIASIILLISHA 1116
            + D+N+ V+YTDIDY VF  ++ ++    SPY   TYRY+PL+++LL+PN YFG    GK +F + DL+  LI+       I R+R L       + + WL NP++ T+S+RGN E+ L  LI+ TL+ L  ++  L+GIL+ L IH K          +IF Y  K ++ P+  + +       +S L + L      + +YG++F+  +YLYH +R D +HNFSV+   LYL S  K     +++  AF+PQLLL+    C   W      L+    + T AFV +NKV TSQYF+W++ FLP  +S   +   + +L++  +W  +QGIWL   Y LEFEG+ +F   ++IAS++  +++ 
Sbjct:   25 YQDANFKVRYTDIDYFVFHDAAKYVYEGKSPYARDTYRYTPLLSWLLVPNHYFGWFHLGKVIFVIFDLVTGLIIMKLLNQAISRKRAL------ILESIWLLNPMVITISTRGNAESVLCCLIMFTLFFLQKSRYTLAGILYGLSIHFKIYPIIYCIPIAIFIYYNKRNQGPRTQLTSL--LNIGLSTLTTLLGCGWAMYKIYGYEFLDQAYLYHLYRTDHRHNFSVWNMLLYLDSANKENGESNLSRYAFVPQLLLVLVTGCLEWWNPTFDNLLRVLFVQTFAFVTYNKVCTSQYFVWYLIFLPFYLSRTHIGWKKGLLMA-TLWVGTQGIWLSQGYYLEFEGKNVFYPGLFIASVLFFVTNV 379
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Nematostella
Match: EDO33030 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STD8])

HSP 1 Score: 244.202 bits (622), Expect = 3.416e-77
Identity = 139/364 (38.19%), Postives = 212/364 (58.24%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDR-------------------FPQILIPNRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLI 1107
            W D    VKYTDIDY+VFT ++  +    SPY   TYRY+PL+A LL PN     +FGK LF + D++   +++ I + R L        S FW +NP+  TVSSRGN E+ +  L+L TLY  L  +  L+G   +L +H K++PIIYS  +F  + +  R                      I  P R      +  + + + ++   +  YG++F++++YLYH  R D+KHNFSVYFY LYL       ++I + AF+PQL++   L++K+ + +   CLL T AFV FNKV TSQYF+W++  LP A+  + +S  R++++++  WF +QG+WL AAY LEF+G   F+ +W+ASI+  +
Sbjct:   27 WQDRTMAVKYTDIDYHVFTDAARHVFYGRSPYERATYRYTPLLAMLLTPNISLNIAFGKVLFILFDILSGFLIFAIQKERGLSYKTCVVSSWFWFFNPMPATVSSRGNAESIMAALVLITLYFALKRKEVLTGFFLALAVHFKIFPIIYSLPLFLLIGERSRDAGLSKSWSNGGLELCKALLGYIFRPAR--VILVLVCVTTLVGLTLGLYVSYGFEFLEHTYLYHVTRTDLKHNFSVYFYMLYLTQDMPWSRVIGLLAFVPQLVMTVVLAFKYYRDICFCCLLQTFAFVTFNKVCTSQYFLWYLCLLPLAVPYIRVSLSRALVMAFS-WFAAQGLWLLAAYYLEFQGFNTFIFIWLASIVFFV 387
[Close]
BLAST of GPI mannosyltransferase 1 vs. Ensembl Medaka
Match: pigm (phosphatidylinositol glycan anchor biosynthesis class M [Source:NCBI gene;Acc:101166013])

HSP 1 Score: 244.202 bits (622), Expect = 9.041e-77
Identity = 149/388 (38.40%), Postives = 219/388 (56.44%), Query Frame = 1 
Query:   73 WHDSNYTVKYTDIDYNVFTKSSYFIKSNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLIDRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFXXXXXXXXXXXXXXNQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTD------------RFPQILIP---NRNHFKXXXXXXXXXXXXXXXXXXXYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYLLSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKVATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLEFEGQQMFLIVWIASIILLISHAVQIRLMSQLFA-----KELDKNKSS 1176
            + D N  VKYTDIDY+VFT ++ FI    SPY   TYRY+PL+A+LL PN Y    FGK LF VCD++  L++Y +   R +       +S+ WL NPL   VSSRGN E+ L  L+L TL  + + ++  +  L+ L +H+K+YP+ Y+  I   L  +             R P   +    N     FA      F  +++LF+ +YGW F+  +Y YH  R DI+HNFS YFY LYL + ++  + + +AAF+PQL+LL   SW     L  +C L T  FV+FNKV TSQYF+W++  LP  +  +TL S++  L    +WF  Q +WL  AY LEFEG   F ++W+A +  L+ ++    ++ Q+ A     K L++ K+ 
Sbjct:   33 YQDRNMVVKYTDIDYHVFTDAARFITEGQSPYNRSTYRYTPLLAWLLTPNIYLTVVFGKLLFIVCDVLSGLLIYKLLCLRGVGCQTARYVSSLWLLNPLPMGVSSRGNAESILSALVLGTLLCMEVRRLAWAAALYGLSVHMKIYPVTYALPIALSLRSSHTETNGTTQSWTWRTPVAFVGSFLNSKLILFASVAGGVFFTLTALFYYMYGWVFLHETYFYHLTRRDIRHNFSPYFYMLYLTADSRWSQSLGLAAFLPQLILLLVSSWTFHPDLAFTCFLHTAVFVSFNKVCTSQYFLWYLSLLPLVIPHLTL-SVKQGLGLLLLWFAGQAVWLAPAYFLEFEGYNTFFLIWLAGLFFLVINSF---ILVQIIAHYRSRKSLERQKAE 416
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BLAST of GPI mannosyltransferase 1 vs. Planmine SMEST
Match: SMESG000029206.1 (SMESG000029206.1)

HSP 1 Score: 134.806 bits (338), Expect = 3.342e-39
Identity = 66/66 (100.00%), Postives = 66/66 (100.00%), Query Frame = -1 
Query:  804 MQYEIKTERKLDKVTQLIAFGKKNICHMKYCDVATLLKATKAMVHNKQLTINRCLCFQLKKHKSNN 1001
            MQYEIKTERKLDKVTQLIAFGKKNICHMKYCDVATLLKATKAMVHNKQLTINRCLCFQLKKHKSNN
Sbjct:    1 MQYEIKTERKLDKVTQLIAFGKKNICHMKYCDVATLLKATKAMVHNKQLTINRCLCFQLKKHKSNN 66
The following BLAST results are available for this feature:
BLAST of GPI mannosyltransferase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
PIGM3.139e-7137.76phosphatidylinositol glycan anchor biosynthesis cl... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
B0491.13.470e-5935.15GPI mannosyltransferase 1 [Source:UniProtKB/TrEMB... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
PIG-M5.816e-3831.40gene:FBgn0034649 transcript:FBtr0071680[more]
PIG-M5.816e-3831.40gene:FBgn0034649 transcript:FBtr0071681[more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pigm1.067e-4638.46phosphatidylinositol glycan anchor biosynthesis, c... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
g6pc.24.025e-6138.46glucose-6-phosphatase, catalytic subunit, gene 2 [... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Pigm9.423e-7138.02phosphatidylinositol glycan anchor biosynthesis, c... [more]
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BLAST of GPI mannosyltransferase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q66IJ4|PIGM_XENTR3.067e-7338.97GPI mannosyltransferase 1 OS=Xenopus tropicalis OX... [more]
sp|Q4R4E1|PIGM_MACFA3.529e-7237.11GPI mannosyltransferase 1 OS=Macaca fascicularis O... [more]
sp|Q9EQY6|PIGM_RAT9.121e-7138.28GPI mannosyltransferase 1 OS=Rattus norvegicus OX=... [more]
sp|Q5RAH7|PIGM_PONAB1.508e-7037.76GPI mannosyltransferase 1 OS=Pongo abelii OX=9601 ... [more]
sp|Q9H3S5|PIGM_HUMAN1.508e-7037.76GPI mannosyltransferase 1 OS=Homo sapiens OX=9606 ... [more]
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BLAST of GPI mannosyltransferase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2U9CY025.432e-8140.90GPI mannosyltransferase 1 OS=Scophthalmus maximus ... [more]
A0A3B4TM411.156e-7943.14GPI mannosyltransferase 1 OS=Seriola dumerili OX=4... [more]
A0A4V6ATC65.068e-7942.46GPI mannosyltransferase 1 OS=Collichthys lucidus O... [more]
A0A4U5VIR66.561e-7942.74GPI mannosyltransferase 1 OS=Collichthys lucidus O... [more]
A0A060WQB79.947e-7943.18GPI mannosyltransferase 1 OS=Oncorhynchus mykiss O... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pigm2.663e-7138.62phosphatidylinositol glycan anchor biosynthesis cl... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
GPI141.060e-5836.54Glycosylphosphatidylinositol-alpha 1,4 mannosyltra... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO330303.416e-7738.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GPI mannosyltransferase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pigm9.041e-7738.40phosphatidylinositol glycan anchor biosynthesis cl... [more]
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BLAST of GPI mannosyltransferase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000029206.13.342e-39100.00SMESG000029206.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031698 ID=SMED30031698|Name=GPI mannosyltransferase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1187bp
ATGAATACAGTTAGAAAGTTAATTTTGCTTTCTGCAATTTTATTACGAAT
TCTGCTAGTTTTATATAGTTCATGGCATGATAGTAATTATACAGTAAAAT
ACACTGATATTGATTATAATGTATTTACAAAATCCAGCTACTTTATTAAA
TCCAACATGTCTCCTTATTTGGAAAAAACTTATAGATATTCTCCTTTGGT
CGCTTATTTATTGCTGCCAAACTTTTACTTTGGTCAATCATTTGGAAAGT
TTTTATTTTGTGTTTGCGATTTAATTTGCAGCTTAATAATGTATTTGATT
GATAGAAGACGTAAGTTAAAAACTAATATTTTTTATTGCATATCAGCGTT
TTGGTTGTATAATCCATTAATTTTTACTGTTTCATCAAGAGGAAATGTTG
AGGCATTTTTGGGAGTATTAATCCTTTCAACATTATATTCTTTATTGTTA
AACCAAATCTGTTTATCTGGCATATTATTCAGTTTATGCATTCATCTTAA
ATTATATCCAATTATTTATTCATTTTCAATATTTTTCTATCTTTGTAAAA
CTGACAGATTTCCACAAATTTTGATTCCTAATCGCAACCATTTTAAATTT
GCAATATCTGTTTTGTTATCGTTTTTATTAATTTCAAGTTTATTTTTTAA
TTTGTATGGTTGGGATTTCATTCAAAATTCATATTTATACCATTTTCATC
GAGTGGATATTAAACATAATTTTTCAGTTTATTTTTATTCCTTGTATTTA
TTGAGTGGTACTAAATTATGTAAATTGATTAGTATTGCAGCCTTCATTCC
TCAGTTATTGCTTTTATGTTTTTTAAGTTGGAAACATAGACAACGATTAA
TTGTCAGCTGCTTGTTGTGTACCATTGCTTTTGTGGCCTTCAATAAAGTA
GCAACGTCACAATATTTCATGTGGCATATGTTCTTTTTGCCAAATGCTAT
GAGCTGTGTTACTTTGTCAAGTTTACGTTCAGTTTTGATTTCATACTGCA
TTTGGTTTATGAGCCAAGGCATTTGGCTATGGGCAGCTTATAAATTAGAA
TTTGAAGGACAACAAATGTTTCTAATTGTTTGGATTGCTTCTATAATCCT
ATTAATCAGTCATGCTGTGCAAATTAGGTTAATGAGCCAATTATTTGCTA
AAGAACTTGATAAAAATAAATCTTCGTAAAATAAAAA
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protein sequence of SMED30031698-orf-1

>SMED30031698-orf-1 ID=SMED30031698-orf-1|Name=SMED30031698-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=393bp
MNTVRKLILLSAILLRILLVLYSSWHDSNYTVKYTDIDYNVFTKSSYFIK
SNMSPYLEKTYRYSPLVAYLLLPNFYFGQSFGKFLFCVCDLICSLIMYLI
DRRRKLKTNIFYCISAFWLYNPLIFTVSSRGNVEAFLGVLILSTLYSLLL
NQICLSGILFSLCIHLKLYPIIYSFSIFFYLCKTDRFPQILIPNRNHFKF
AISVLLSFLLISSLFFNLYGWDFIQNSYLYHFHRVDIKHNFSVYFYSLYL
LSGTKLCKLISIAAFIPQLLLLCFLSWKHRQRLIVSCLLCTIAFVAFNKV
ATSQYFMWHMFFLPNAMSCVTLSSLRSVLISYCIWFMSQGIWLWAAYKLE
FEGQQMFLIVWIASIILLISHAVQIRLMSQLFAKELDKNKSS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000421tail
Vocabulary: INTERPRO
TermDefinition
IPR007704PIG-M
Vocabulary: biological process
TermDefinition
GO:0006506GPI anchor biosynthetic process
Vocabulary: molecular function
TermDefinition
GO:0016758transferase activity, transferring hexosyl groups
GO:0016740transferase activity
GO:0016757transferase activity, transferring glycosyl groups
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007704GPI mannosyltransferase 1PFAMPF05007Mannosyl_transcoord: 126..372
e-value: 2.0E-64
score: 217.9
IPR007704GPI mannosyltransferase 1PANTHERPTHR12886PIG-M MANNOSYLTRANSFERASEcoord: 6..379
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.708
NoneNo IPR availableTMHMMTMhelixcoord: 109..126
NoneNo IPR availableTMHMMTMhelixcoord: 200..222
NoneNo IPR availableTMHMMTMhelixcoord: 355..377
NoneNo IPR availableTMHMMTMhelixcoord: 74..96
NoneNo IPR availableTMHMMTMhelixcoord: 7..24
NoneNo IPR availableTMHMMTMhelixcoord: 157..179
NoneNo IPR availableTMHMMTMhelixcoord: 324..346
NoneNo IPR availableTMHMMTMhelixcoord: 282..304
NoneNo IPR availableTMHMMTMhelixcoord: 258..275