DNA-directed RNA polymerases I and III subunit RPAC1

Overview
NameDNA-directed RNA polymerases I and III subunit RPAC1
Smed IDSMED30031697
Length (bp)1685
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DNA-directed RNA polymerases I and III subunit RPAC1 (SMED30031697) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA-directed RNA polymerases I and III subunit RPAC1 (SMED30031697) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA-directed RNA polymerases I and III subunit RPAC1 (SMED30031697) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DNA-directed RNA polymerases I and III subunit RPAC1 (SMED30031697) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031697

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
neoblastSMED30031697h1SMcG0017054 dd_Smed_v4_5608_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 124.79 bits (312), Expect = 7.934e-31
Identity = 86/323 (26.63%), Postives = 164/323 (50.77%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYI 1048
             ++ F V+++  D   L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +    +++ +E D+   L F L V   +                N +A +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V + +L +  ++  +  E LK  V +    + +I+ VES      P   ++  A++ ++ KCR +L  L+ +
Sbjct:   45 FEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG--DEEGTEIDT---LQFRLQVRCTR----------------NPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRL-DTFSREIFRNEKLKKVVRLARVRDHYIFSVEST--GVLPPDVLVSEAIKVLMGKCRRFLDELDAV 343
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 118.627 bits (296), Expect = 4.001e-29
Identity = 84/311 (27.01%), Postives = 157/311 (50.48%), Query Frame = 2 
Query:  137 DNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYI 1048
            D   L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +    +++ +E D+   L F L V   +                N +A +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V + +L +  ++  +  E LK  V +    + +I+ VES      P   ++  A++ ++ KCR +L  L+ +
Sbjct:    2 DENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG--DEEGTEIDT---LQFRLQVRCTR----------------NPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRL-DTFSREIFRNEKLKKVVRLARVRDHYIFSVEST--GVLPPDVLVSEAIKVLMGKCRRFLDELDAV 288
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 113.62 bits (283), Expect = 4.858e-27
Identity = 77/288 (26.74%), Postives = 146/288 (50.69%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQV 943
             ++ F V+++  D   L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +    +++ +E D+   L F L V   +                N +A +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V + +L +  ++  +  E LK  V +    + +I+ V
Sbjct:   45 FEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG--DEEGTEIDT---LQFRLQVRCTR----------------NPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRL-DTFSREIFRNEKLKKVVRLARVRDHYIYGV 310
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 111.309 bits (277), Expect = 2.009e-26
Identity = 75/278 (26.98%), Postives = 141/278 (50.72%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIG 913
             ++ F V+++  D   L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +    +++ +E D+   L F L V   +                N +A +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V + +L +  ++  +  E LK  V + 
Sbjct:   45 FEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG--DEEGTEIDT---LQFRLQVRCTR----------------NPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRL-DTFSREIFRNEKLKKVVRLA 300
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 111.309 bits (277), Expect = 2.009e-26
Identity = 75/278 (26.98%), Postives = 141/278 (50.72%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIG 913
             ++ F V+++  D   L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +    +++ +E D+   L F L V   +                N +A +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V + +L +  ++  +  E LK  V + 
Sbjct:   45 FEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG--DEEGTEIDT---LQFRLQVRCTR----------------NPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRL-DTFSREIFRNEKLKKVVRLA 300
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Celegans
Match: rpac-40 (RNA Polymerase I/III (A/C) shared subunit [Source:UniProtKB/TrEMBL;Acc:Q9UAY9])

HSP 1 Score: 147.902 bits (372), Expect = 2.341e-39
Identity = 105/339 (30.97%), Postives = 180/339 (53.10%), Query Frame = 2 
Query:   92 VNDLKEKFNVNIL--SCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPN--------DDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVK----LTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKI-KKG---VATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITE 1054
            +N+  ++  V ++  S D   L+F+I  + +     LR+++I EVP++A++++YLY NTS I+D  L  R+ L P+ V+P   +F   +           D++ E D    LIF ++V+  K                N+NAV       +   + +VYS    W PI DQ  +F++      +++D+++ +L P +EI     AVK  G +HAKF PV+ A  R   T++L + I+G +A  L+S+F EGVI I KKG   +A V DA+  +  ++N + +EDL   V++G ++  FI+ VES       +++++V A + M  KCR     +E + +
Sbjct:   47 INEYCDQIQVAMVNESDDGMTLEFDITRIEAPIANALRRVLIAEVPTMALEKIYLYQNTSVIQDEVLCHRLGLLPLRVDPRGFQFPKEKVVGINEKGVDCDEEPEGDPAKNLIFKINVSCTK----------------NRNAVPTATDPKQLYHNSSVYSRAFEWVPIADQKTQFTEEAHPRMVSDDILVAKLRPGQEIEASCHAVKGIGRDHAKFSPVATASYRLLPTIRLNAEISGEAAERLKSVFSEGVIAIEKKGAKRIAVVKDARK-DTCSRNVFRHEDLSKVVQLGKNKQHFIFSVESTGALK--SSELVVEACKVMEIKCRSLRKQIEALIQ 366
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Fly
Match: CG3756 (gene:FBgn0031657 transcript:FBtr0078994)

HSP 1 Score: 138.272 bits (347), Expect = 4.030e-36
Identity = 103/322 (31.99%), Postives = 167/322 (51.86%), Query Frame = 2 
Query:   89 SVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKG-VATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLE 1042
            SV   KEK ++ I+  D + L+F++  +        R+L++++VPS+AI+++Y+YNNTS I+D  L  R+ L P+  +P L   Y +E   +  +E D+   L F+L V  ++ +  D  + +   D + KN                VYS  L W P G QA  +S+  +    +D+++ +L P  E+ L  +AVK  G +HAKF PV+ A  R    +KL   +TG  A  LQ+ F  GVI I +   A V DA+  +  ++N Y Y  L D V +    + +I+ VESV    +P   I + A++ +  KCR  +  +E
Sbjct:   33 SVQAFKEKLHIKIVRNDEDGLEFDLIGVYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRMGLLPLRADPRLFA-YRTEESTEAGTEQDT---LEFELKVKCSRRR--DAGKDQSNFDDIYKN--------------HKVYSGHLKWLPKGKQAQIYSESAVNCIHDDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVATATYRLLPMIKLNREVTGKDAYLLQNCFSPGVIGIDENETAYVKDARY-DTCSRNVYRYPQLNDAVTLARIRDHYIFSVESV-GALKPDV-IFLEAVKVLKRKCRALIDEIE 331
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Zebrafish
Match: polr1c (RNA polymerase I and III subunit C [Source:ZFIN;Acc:ZDB-GENE-040426-1495])

HSP 1 Score: 140.198 bits (352), Expect = 2.000e-36
Identity = 97/321 (30.22%), Postives = 170/321 (52.96%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTE---DVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLE 1042
             K+ F + I+S D   L+F++  + +      R++++ EVP++AI+++++YNNTS I+D  L  R+ L P+  +P L E+ +SE  + + +E D+   L   +    N     D+S      DP      E +L       +  +YS D+ W PIG+QA  F+D K+     D++L ++ P +E+ ++   VK  G +HAKF PV+ A  R    + LL  I G  A  L+  F  GVI+++    + VA V +++L +  ++    ++DLK  V++G   + FI+ VES      P   ++  A+  ++ KC+ +L  LE
Sbjct:   61 FKKNFRIEIISSDENTLEFDMIGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKADPRLFEYRNSE--DQEGTEIDTIQ-LQLKVKCTRNPRAPKDSS------DP-----KELYL-------NHMIYSGDIKWLPIGNQADVFADAKIGPVHGDILLAQVRPGQELDIVMHCVKGIGKDHAKFSPVATASYRLLPEITLLQTIEGEQAERLKRCFSPGVIELENVNGRKVAKVVNSRL-DTCSREVLRHDDLKSLVKLGRVRDHFIFSVEST--GILPPDVLVTEAINVLMSKCQKFLTELE 357
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Zebrafish
Match: polr1c (RNA polymerase I and III subunit C [Source:ZFIN;Acc:ZDB-GENE-040426-1495])

HSP 1 Score: 68.5514 bits (166), Expect = 6.433e-13
Identity = 31/95 (32.63%), Postives = 60/95 (63.16%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDS 385
             K+ F + I+S D   L+F++  + +      R++++ EVP++AI+++++YNNTS I+D  L  R+ L P+  +P L E+ +SE  + + +E D+
Sbjct:   61 FKKNFRIEIISSDENTLEFDMIGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKADPRLFEYRNSE--DQEGTEIDT 153
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Zebrafish
Match: polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:ZFIN;Acc:ZDB-GENE-030131-6609])

HSP 1 Score: 50.447 bits (119), Expect = 2.017e-6
Identity = 51/200 (25.50%), Postives = 90/200 (45.00%), Query Frame = 2 
Query:  119 VNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLE--FYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSA 712
            V I    +E +KF I N       ++R++ ++EVP++AID + +  N+S + D  +  R+ L P+  + D+++   YS +   DD   F  +  +   LDV   +    D +R     D L+ N   + +P     RD                    +D    +D++L +L   +E+ L A A K +G  HAK+ P + 
Sbjct:    9 VKITELSDENVKFVIENTDLAVANSIRRVFMSEVPTIAIDWVQIDANSSVLHDEFVAHRVGLIPL-TSDDIVDKMQYSRDCTCDD---FCPECSVELTLDVRCTE----DQTRHVTSRDLLSNNP--RVIPVTSRSRDNDP-----------------NDYVEQDDILLVKLRKGQELRLRAYAKKGFGKEHAKWNPTAG 181
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Xenopus
Match: POLR1C (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:100379802])

HSP 1 Score: 122.865 bits (307), Expect = 2.016e-30
Identity = 85/290 (29.31%), Postives = 152/290 (52.41%), Query Frame = 2 
Query:  113 FNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDV----KLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRP 958
            F ++I+  + + L+F++  + +      R++++ EVP++A++++Y+YNNTS I+D  L  R+ L P+ V+P L E+ S+E    + +E D+   L F+L+V   +  +      +  +DP      E +L       +  VY+  + W P G+Q+  F +      +  D+++ +L P +EI +I   VK  G +HAKF PV+ A  R    + LL PI G  A  LQ  F  GVI +     K VA V +A+  +   +  + ++DLKD V +    + +I +  ++ P
Sbjct:   49 FRIDIVKMEGDTLEFDMVGIDASIANAFRRILLAEVPTMAVEKVYVYNNTSIIQDEILAHRLGLIPIRVDPRLFEYRSAE--EGEGTEIDT---LQFELNVKCTRNPRAS----KDCSDP-----NELYL-------NHKVYTSHMKWLPQGNQSDLFPETDPPRPVHGDILIAQLRPGQEISVIMHCVKGIGKDHAKFSPVATASYRLLPEITLLCPIEGELADRLQRCFSPGVIGVDEVDGKRVARVINAR-TDTCGREIFCHDDLKDLVRMARVRDYYICKCTALGP 316
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Xenopus
Match: POLR1C (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:100379802])

HSP 1 Score: 121.324 bits (303), Expect = 1.465e-29
Identity = 84/292 (28.77%), Postives = 152/292 (52.05%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDV----KLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKI----KKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESV 952
             +  F ++I+  + + L+F++  + +      R++++ EVP++A++++Y+YNNTS I+D  L  R+ L P+ V+P L E+ S+E    + +E D+   L F+L+V   +  +      +  +DP      E +L       +  VY+  + W P G+Q+  F +      +  D+++ +L P +EI +I   VK  G +HAKF PV+ A  R    + LL PI G  A  LQ  F  GVI +     K VA V +A+  +   +  + ++DLKD V +    + +I +  ++
Sbjct:   45 FENNFRIDIVKMEGDTLEFDMVGIDASIANAFRRILLAEVPTMAVEKVYVYNNTSIIQDEILAHRLGLIPIRVDPRLFEYRSAE--EGEGTEIDT---LQFELNVKCTRNPRAS----KDCSDP-----NELYL-------NHKVYTSHMKWLPQGNQSDLFPETDPPRPVHGDILIAQLRPGQEISVIMHCVKGIGKDHAKFSPVATASYRLLPEITLLCPIEGELADRLQRCFSPGVIGVDEVDGKRVARVINAR-TDTCGREIFCHDDLKDLVRMARVRDYYICKCTAL 314
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Xenopus
Match: ttll1 (tubulin tyrosine ligase like 1 [Source:Xenbase;Acc:XB-GENE-920807])

HSP 1 Score: 51.6026 bits (122), Expect = 1.273e-6
Identity = 51/200 (25.50%), Postives = 91/200 (45.50%), Query Frame = 2 
Query:  119 VNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLE--FYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSA 712
            V I    +E +KF + N       ++R++ I EVP++AID + +  N+S + D  +  R+ L P+  + D+++   YS +   D   EF  +  + F LDV  N+    D +R     D ++ N   + +P     RD                    +D    +D+++ +L   +E+ L A A K +G  HAK+ P + 
Sbjct:    9 VRITELTDENVKFIVENTDLAIANSIRRVFIAEVPTIAIDWVQIDANSSVLHDEFIAHRVGLIPL-TSDDIVDKLQYSRDCTCD---EFCPECSVEFTLDVRCNE----DQTRHVTSRDLVSNNL--RVIPVTSRSRDNDP-----------------NDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAG 181
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Mouse
Match: Polr1c (polymerase (RNA) I polypeptide C [Source:MGI Symbol;Acc:MGI:103288])

HSP 1 Score: 132.88 bits (333), Expect = 6.791e-34
Identity = 90/325 (27.69%), Postives = 163/325 (50.15%), Query Frame = 2 
Query:   95 NDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYI 1048
            N  ++ F V+++  D + L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L      EY N  + E      L F L V   +                N NA +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V +A+L +  ++  + +E LK  V +    + +I+ VES      P   ++  A++ ++ KCR +L  L+ +
Sbjct:   43 NRFEKNFRVDVVQMDEDTLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLF-----EYRNQGEEEGTEIDTLQFRLQVRCTR----------------NPNAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRPVHDDILIAQLRPGQEIDLMMHCVKGIGKDHAKFSPVATASYRLLPAITLLEPVEGEAAEELSQCFSPGVIEVEEVQGKKVARVANARL-DTFSREIFRHEKLKKAVRLARVRDHYIFSVEST--GVLPPDVLVSEAIKILMGKCRRFLDELDAV 343
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Mouse
Match: Polr1c (polymerase (RNA) I polypeptide C [Source:MGI Symbol;Acc:MGI:103288])

HSP 1 Score: 108.997 bits (271), Expect = 3.020e-26
Identity = 79/281 (28.11%), Postives = 141/281 (50.18%), Query Frame = 2 
Query:  227 VAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYI 1048
            +A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +     ++ +E D+   L F L V   +                N NA +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V +A+L +  ++  + +E LK  V +    + +I+ VES      P   ++  A++ ++ KCR +L  L+ +
Sbjct:    1 MAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLFEYRNQG--EEEGTEIDT---LQFRLQVRCTR----------------NPNAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRPVHDDILIAQLRPGQEIDLMMHCVKGIGKDHAKFSPVATASYRLLPAITLLEPVEGEAAEELSQCFSPGVIEVEEVQGKKVARVANARL-DTFSREIFRHEKLKKAVRLARVRDHYIFSVEST--GVLPPDVLVSEAIKILMGKCRRFLDELDAV 257
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Mouse
Match: Polr1c (polymerase (RNA) I polypeptide C [Source:MGI Symbol;Acc:MGI:103288])

HSP 1 Score: 83.1889 bits (204), Expect = 2.187e-17
Identity = 59/229 (25.76%), Postives = 106/229 (46.29%), Query Frame = 2 
Query:   95 NDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINE----------------VPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGR 724
            N  ++ F V+++  D + L+F++  + +      R++++ E                VP++A++++ +YNNTS ++D  L  R+ L P+  +P L      EY N  + E      L F L V   +                N NA +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R
Sbjct:   43 NRFEKNFRVDVVQMDEDTLEFDMVGIDAAIANAFRRILLAEAGGWVEVSCLLCLLGQVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLF-----EYRNQGEEEGTEIDTLQFRLQVRCTR----------------NPNAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRPVHDDILIAQLRPGQEIDLMMHCVKGIGKDHAKFSPVATASYR 250
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Mouse
Match: Polr1c (polymerase (RNA) I polypeptide C [Source:MGI Symbol;Acc:MGI:103288])

HSP 1 Score: 50.8322 bits (120), Expect = 5.219e-7
Identity = 37/145 (25.52%), Postives = 67/145 (46.21%), Query Frame = 2 
Query:  215 EVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDE 640
            +VP++A++++ +YNNTS ++D  L  R+ L P+  +P L      EY N  + E      L F L V   +                N NA +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +
Sbjct:   47 KVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLF-----EYRNQGEEEGTEIDTLQFRLQVRCTR----------------NPNAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRPVHDDILIAQLRPGQ 170
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. UniProt/SwissProt
Match: sp|P07703|RPAC1_YEAST (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPC40 PE=1 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 1.398e-40
Identity = 105/295 (35.59%), Postives = 154/295 (52.20%), Query Frame = 2 
Query:   89 SVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDP--LNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSD---VKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGV--ATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESV 952
            +V   K+ F VNI S D  +  F++ N+ +      R+++I+EVPSVA + +Y +NNTS I+D  L  RI L P+ V+PD+L +  S  P+D+K  F  +  ++  L+V   +    +    +  TDP  L  NA               VY+ DL + P G Q+  F+D   V    D++L +L P +EI L A  +   G +HAKF PVS A  R    + +L PI G SA   Q  FP GVI I +G   A V DA+  +  ++    YE+  DKV++G   N FI+ VES 
Sbjct:   32 NVEKFKKDFEVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNLPDDEK--FTDENTIVLSLNVKCTR----NPDAPKGSTDPKELYNNA--------------HVYARDLKFEPQGRQSTTFADCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARK-DTVSREVLRYEEFADKVKLGRVRNHFIFNVESA 305
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. UniProt/SwissProt
Match: sp|O94616|RPAC1_SCHPO (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpc40 PE=3 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 2.072e-37
Identity = 90/294 (30.61%), Postives = 154/294 (52.38%), Query Frame = 2 
Query:   92 VNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKL---TEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGV-----ATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVES 949
            ++  K+   V+I S D E + FEI  + +      R+++I E+P++A + +Y+ NNTS I+D  L  RI L P+  +PD+ +++    P  + +  D    ++F L+      KK +           NKNA        +   +  VYS DL+W+P G Q  +F+D  +     D+++ +L P +EI L A A+   G +HAKF PV+ A  R   T+ +LSPI G  A+  Q  FP+GVI++++G      A V D +  +  ++    + +  DKV++G   + +++ VES
Sbjct:   39 LDKFKKNLKVSITSLDQETMVFEISGIDASIANAFRRILIAEIPTLAFEFVYIINNTSIIQDEVLSHRIGLVPISADPDMFKWFQHPLPGQEATHTDYD-TVVFSLN------KKCE----------FNKNAATDEKDPKRLYVNSEVYSGDLIWKPQGRQEERFADNPIRVVNPDIVVAKLRPGQEIDLEAHAILGIGQDHAKFSPVATASYRLLPTIHILSPIEGEDAVKFQKCFPKGVIELEEGPDGKKQARVADVRK-DTVSRECLRHPEFADKVQLGRVRDHYLFSVES 314
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. UniProt/SwissProt
Match: sp|P52432|RPAC1_MOUSE (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Mus musculus OX=10090 GN=Polr1c PE=1 SV=3)

HSP 1 Score: 132.88 bits (333), Expect = 4.750e-33
Identity = 90/325 (27.69%), Postives = 163/325 (50.15%), Query Frame = 2 
Query:   95 NDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYI 1048
            N  ++ F V+++  D + L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L      EY N  + E      L F L V   +                N NA +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V +A+L +  ++  + +E LK  V +    + +I+ VES      P   ++  A++ ++ KCR +L  L+ +
Sbjct:   43 NRFEKNFRVDVVQMDEDTLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLF-----EYRNQGEEEGTEIDTLQFRLQVRCTR----------------NPNAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRPVHDDILIAQLRPGQEIDLMMHCVKGIGKDHAKFSPVATASYRLLPAITLLEPVEGEAAEELSQCFSPGVIEVEEVQGKKVARVANARL-DTFSREIFRHEKLKKAVRLARVRDHYIFSVEST--GVLPPDVLVSEAIKILMGKCRRFLDELDAV 343
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. UniProt/SwissProt
Match: sp|O15160|RPAC1_HUMAN (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 3.810e-30
Identity = 86/323 (26.63%), Postives = 164/323 (50.77%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYI 1048
             ++ F V+++  D   L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +    +++ +E D+   L F L V   +                N +A +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V + +L +  ++  +  E LK  V +    + +I+ VES      P   ++  A++ ++ KCR +L  L+ +
Sbjct:   45 FEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG--DEEGTEIDT---LQFRLQVRCTR----------------NPHAAKDSSDPNELYVNHKVYTRHMTWIPLGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRL-DTFSREIFRNEKLKKVVRLARVRDHYIFSVEST--GVLPPDVLVSEAIKVLMGKCRRFLDELDAV 343
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. UniProt/SwissProt
Match: sp|Q32L22|RPAC1_BOVIN (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Bos taurus OX=9913 GN=POLR1C PE=2 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 1.158e-29
Identity = 86/323 (26.63%), Postives = 163/323 (50.46%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYI 1048
             ++ F V+++  D   L+F++  + +      R++++ EVP++A++++ +YNNTS ++D  L  R+ L P+  +P L E+ +    ++  +E D+   L F L V   +                N +A +      +   +  VY+  + W P+G+QA  F +  +    +D+++ +L P +EI L+   VK  G +HAKF PV+ A  R    + LL P+ G +A  L   F  GVI+++    K VA V + +L +  ++  +  E LK  V +    + FI+ VES      P   ++  A++ ++ KC+ +L  L+ +
Sbjct:   45 FEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG--DEGGTEIDT---LQFRLQVRCTR----------------NPHAAKDSSDPNELYVNHRVYTRHMTWVPLGNQADLFPEGAIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEIQGKKVARVANPRL-DTFSREVFRNEKLKKVVRLARVRDHFIFSVEST--GVLPPDVLVSEAIKVLMGKCQRFLDELDAV 343
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. TrEMBL
Match: H2KQJ0 (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Clonorchis sinensis OX=79923 GN=CLF_104038 PE=4 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 6.551e-51
Identity = 149/475 (31.37%), Postives = 239/475 (50.32%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDK-SEFDSKACLIFDLDVNYNK--LKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVK---LTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKI--KKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGN-----TNRKLDYKSYARQVCGKTCFIE-KDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAY---HRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSF 1417
            +EH     P      S    + KF V+I+   ++ L+F++ ++   F   LR+++I EVPS++I+R+YL+ NTS + D  L  R+ L P+ + P  L F S   P  D+ +EF+    +IFD  V++ K  LK    S  ++F   LN       LP+    R   VYS +L W P+  Q   F + +   ++  +++N+L   +EI    +AVK  G +HAKF PV+AA+ +    +KLL PI G+ A  LQ  F  GVI I  K   A + +A+L   + ++    +   D V +G+D +  I+ VES+ P  +P A+++ SA+  MIEKC  YL  ++       + +G N      +RK +  S+  ++  +   +E   ++       Y FHGE  TLG++L Y +  L   K   C Y   H +E  I   V+V NG+  +  L EG   +   F  I  + +  L SF
Sbjct:   14 KEHGIINHPGTEEEWSAQIFRSKFEVSIIDM-SDTLEFDMVHIDCSFANALRRILIAEVPSISIERVYLFQNTSVMPDEVLCHRLGLIPLAIVPRHLIFPSRILPETDELTEFNPMEHVIFDFKVSFKKSDLKGCSESSGKEFISDLN-------LPSV---RSSAVYSSELKWVPLPGQEELFGEDQPTVVSPHILINKLAVGDEIEARCVAVKGVGRDHAKFSPVAAAYYKFLPVIKLLRPIEGDEARLLQRSFAHGVIGIDPKTEQAYILNARLDNGSREHMRHPQFRDDAVFVGVDSSHCIFTVESIAPSQRPPARLVRSAIEVMIEKCGHYLAIVDKPGFGDVVVEGVNLVTPAGDRKSETGSFHSRLNDRDVGLEVAHMSRDKRRITYTFHGEDHTLGLALRYCI--LHSTKATFCGYCVPHPLEDKIHFDVQVKNGSAHDA-LREGLLCLRDCFIHIKSAFKAALQSF 474
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. TrEMBL
Match: A0A5J4NFJ8 (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Paragonimus westermani OX=34504 GN=DEA37_0000978 PE=4 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.052e-48
Identity = 146/448 (32.59%), Postives = 227/448 (50.67%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYP-NDDKSEFDSKACLIFDLDVNYNK-LKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPI-GDQALKFSDVK--LTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGV--ATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLG----------NLEYITEQQRIEQGGNTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSA-----FYRFHGESDTLGVSLVYLMNYLFGGKRAACAY---HRVELGIELLVRV 1312
            +EH     P    + SV   KE   V  +S  +E L+F++ N+   F   +R+++I EVPSV+I+R+YL  NTS + D  L  R+ L P+ V+P L+ F S + P +D+ S+FD    LIFDL V + K   K    R  K        + E  +P+    R  ++YS +L W P+ G + LK  D    +++ +++N+L   +E+    +AVK  G +HAKF PVSAA+ +    +KLL PI G+ A  LQS F  GVI I      A V + +L   + ++    E  KD V +G      ++ VES+ P H+P A+++ SA+  MI KC+ YL           ++E +  ++ +     T+   + +S   Q+ G+    E  L V + S       Y FHGE  TLG++L + +  L       C Y   H +E  I L V+V
Sbjct:   14 QEHGIITHPGVEESWSVEKFKENLRV-FISNLSETLEFDLINIDCSFANAIRRILIAEVPSVSIERVYLQQNTSIMPDEVLCHRLGLIPLTVDPKLVGFPSKQLPASDELSDFDPSEHLIFDLKVCFTKNCTKPTAGRSGK------DASSEMNIPSV---RSLSIYSSELQWVPLPGQENLKEGDAPTVVSQTILVNKLAVGDELEARCVAVKGIGRDHAKFSPVSAAYYKFMPIIKLLRPIEGDEARLLQSSFAPGVIGIDPQTEQAYVNNPRLDNGSREHLRHLEFRKDSVFVGTCPTHCVFTVESISPTHRPPARLVRSAIEVMINKCKHYLAITKKPGFGDISVENLDTKEELSGKAQTSHS-NTESVRSQLNGR----EVGLEVAHTSPDKRRITYTFHGEDHTLGLALRFCI--LHSTHATFCGYCVPHPLEDKIHLDVQV 444
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. TrEMBL
Match: W6UQQ3 (DNA-directed RNA polymerases I and III subunit RPAC1 OS=Echinococcus granulosus OX=6210 GN=EGR_01630 PE=4 SV=1)

HSP 1 Score: 185.267 bits (469), Expect = 1.985e-48
Identity = 141/466 (30.26%), Postives = 220/466 (47.21%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPN-DDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSD------VKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKI--KKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYL------GNLEYITEQQRIEQGGN---TNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAA-CAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFI 1384
            ++H   + PS      V+    +F V + S   E ++F++ ++   F  ++R+++++EVPS AIDR+YLY NTS I D     R+ L P++V+PD + F S++ P+ DD S FD  + LIFDL+V   +         E  +D   K + + F           +YS  L W P+  Q   F +        ++  V+LN+L P +EI    LAVK  G +HAKF PVSAA  +   ++++   + G+ A  LQ  F +GVI +  +  VA+V DA+L +  ++    + DL   V + L+   FI+ VES+ P ++P   ++ SA+  M+ KC  YL      G          +E GG               R V     F+  DL      A +RF GE  TLG  L Y +      K    C  H +E  I   ++ S       IL  G   + + F+ I
Sbjct:   12 KQHGLSFIPSAPQKWDVDIFISEFQVVVTSFTPETIEFDMISIDCTFANSIRRILVSEVPSFAIDRVYLYQNTSVIADETFCHRLGLVPLNVDPDKMSFCSTDLPDTDDLSGFDPNSHLIFDLNVKAARPSS------EGNSDSQPKESFQSF----------PLYSSSLTWVPLPGQEDAFKNEGASYPAPVSRKVLLNKLGPGDEIMARCLAVKGVGRDHAKFSPVSAAFYKLLPSIEINGVVRGDLAKKLQRSFAKGVIDVDPRTQVASVADARL-DNGSREHLRHPDLASIVHVFLNPRHFIFTVESIAPGYRPPDTLVKSAIDVMLSKCAHYLTIVGKPGFAASPLSDPNVEIGGGELPGEEAAKTSLNGRAVGLDVAFVSNDLR----RATFRFTGEDHTLGAPLRYCILRSEAVKLCGYCQPHPLEDSITFEIQ-SRDEMAVTILRNGLYCLRACFEHI 455
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. TrEMBL
Match: A0A068WEZ7 (DNA directed RNA polymerases I and III subunit OS=Echinococcus granulosus OX=6210 GN=EgrG_000860800 PE=4 SV=1)

HSP 1 Score: 184.882 bits (468), Expect = 2.245e-48
Identity = 142/466 (30.47%), Postives = 222/466 (47.64%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPN-DDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSD------VKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKI--KKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYL------GNLEYITEQQRIEQGGN--TNRKLDYKSY-ARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAA-CAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFI 1384
            ++H   + PS      V+    +F V + S   E ++F++ ++   F  ++R+++++EVPS AIDR+YLY NTS I D     R+ L P++V+PD + F S++ P+ DD S FD  + LIFDL+V   +         E  +D   K + + F           +YS  L W P+  Q   F +        ++  V+LN+L P +EI    LAVK  G +HAKF PVSAA  +   ++++   + G+ A  LQ  F +GVI +  +  VA+V DA+L +  ++    + DL   V + L+   FI+ VES+ P ++P   ++ SA+  M+ KC  YL      G          +E GG      +    S   R V     F+  DL      A +RF GE  TLG  L Y +      K    C  H +E  I   ++ S       IL  G   + + F+ I
Sbjct:   12 KQHGLSFIPSAPQKWDVDIFISEFQVVVTSFTPETIEFDMISIDCTFANSIRRILVSEVPSFAIDRVYLYQNTSVIADETFCHRLGLVPLNVDPDKMSFCSTDLPDTDDLSGFDPNSHLIFDLNVKAARPSS------EGNSDSQPKESFQSF----------PLYSSSLTWVPLPGQEDAFKNEGASYPAPVSRKVLLNKLGPGDEIMARCLAVKGVGRDHAKFSPVSAAFYKLLPSIEINGVVRGDLAKKLQRSFAKGVIDVDPRTQVASVADARL-DNGSREHLRHPDLASIVHVFLNPRHFIFTVESIAPGYRPPDTLVKSAIDVMLSKCAHYLTIVGKPGFAASPLSDPNVEIGGGELPGEEASKTSLNGRAVGLDVAFVSNDLR----RATFRFTGEDHTLGAPLRYCILRSEAVKLCGYCQPHPLEDSITFEIQ-SRDEMAVTILRNGLYCLRACFEHI 455
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. TrEMBL
Match: A0A074ZE82 (RPOLD domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_10182 PE=4 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 5.799e-48
Identity = 145/475 (30.53%), Postives = 233/475 (49.05%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDK-SEFDSKACLIFDLDVNYNK--LKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFS---DVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKI--KKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNT-----NRKLDYKSYARQVCGKTCFIE-KDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAY---HRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSF 1417
            +EH     P      S    + KF V+I    ++ L+F++ ++   F   +R+++I EVPS++I+R+YL+ NTS + D  L  R+ L P+ + P  L F S   P  D+ +EF+    ++FD  V++ K  LK    S  ++F    N  +V          R   VYS +L W P+  Q   F       ++  +++N+L   +EI    +AVK  G +HAKF PV+AA+ +    +KLL  I G+ A  LQ  F  GVI I  K   A V +A+L   + ++    +   D V +G+D +  I+ VES+ P  +P A+++ SA+  MIEKC  YL  ++       + +G +      +RKL+  S+  ++  +   +E   ++       Y FHGE  TLG++L Y +  L   K   C Y   H +E  I   V+V NG +    L EG   +   F  I  + +  L SF
Sbjct:   14 KEHGLISYPGAEEEWSTEIFRNKFEVSITDM-SDTLEFDMVHIDCSFANAIRRILIAEVPSISIERVYLFQNTSVMPDEVLCHRLGLVPLAIVPRHLIFPSRSLPETDELTEFNPMEHVVFDFKVSFKKSDLKGCSESSGKEFISEFNIPSV----------RSLAVYSSELKWVPLPGQEELFGADQPTVVSPHILINKLAVGDEIEARCVAVKGVGRDHAKFSPVAAAYYKFLPVIKLLRHIEGDEARLLQRSFARGVIGIDPKTERAYVLNARLDNGSREHMRHPQFRDDAVFVGVDSSHCIFTVESIAPTQRPPARLVRSAIEVMIEKCGHYLAIMDKPGFGDVVVEGVDPVTPAGDRKLETGSFHSRLNDRDVGLEVAHMSRDKRRVTYTFHGEDHTLGLALRYCI--LHSTKATFCGYCVPHPLEDKIHFDVQVKNG-SAHDTLREGLLCLRDCFVHIKLAFKSALQSF 474
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Cavefish
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:103038473])

HSP 1 Score: 139.813 bits (351), Expect = 1.780e-36
Identity = 98/322 (30.43%), Postives = 172/322 (53.42%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEK-FTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLE 1042
             K+ F +NI   D   L+F++  + +      R++++ EVP++AI+++++YNNTS I+D  L  R+ L P+  +P L E+ ++   +++ +E D+    +        K+K    +R  K  +DP      E +L       +  VYS D+ W PIG+QA  F D K+    +D++L +L P +E+ ++   VK  G +HAKF PV+ A  R    + LL  + G  A  L+  F  GVI+++    + VA V +++L +  ++    ++DLK+ V+IG   + FI+ VES      P   ++  A+  +I KC+ +L  LE
Sbjct:   47 FKKNFRLNIAHMDENTLEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKADPRLFEYRNA--GDEEGTEIDTIQLQL--------KIKCTRNTRAAKDSSDP-----KELYL-------NHMVYSKDITWVPIGNQADVFGDSKIGPVHDDILLAQLRPGQELDIVMHCVKGIGKDHAKFSPVATASYRLLPEITLLQTVEGEKAERLKRCFSAGVIEVENINGEQVAKVVNSRL-DTCSREVLRHDDLKNLVKIGRVRDHFIFSVEST--GILPPEVLVSEAINVLIAKCQKFLTELE 343
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Cavefish
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:103038473])

HSP 1 Score: 95.5153 bits (236), Expect = 1.922e-21
Identity = 82/318 (25.79%), Postives = 145/318 (45.60%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEK-FTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLE 1042
             K+ F +NI   D   L+F++  + +      R++++ EVP++AI+++++YNNTS I+D  L  R+ L P+  +P L E+ ++   +++ +E D+    +        K+K    +R  K  +DP      E +L       +  VYS D+ W PIG+QA  F D K+    +D++L +L P +E+ ++   VK  G   AK +                     NS L                          +  ++    ++DLK+ V+IG   + FI+ VES      P   ++  A+  +I KC+ +L  LE
Sbjct:   46 FKKNFRLNIAHMDENTLEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKADPRLFEYRNA--GDEEGTEIDTIQLQL--------KIKCTRNTRAAKDSSDP-----KELYL-------NHMVYSKDITWVPIGNQADVFGDSKIGPVHDDILLAQLRPGQELDIVMHCVKGIGEQVAKVV---------------------NSRL--------------------------DTCSREVLRHDDLKNLVKIGRVRDHFIFSVEST--GILPPEVLVSEAINVLIAKCQKFLTELE 292
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Sea Lamprey
Match: polr1c (RNA polymerase I and III subunit C [Source:ZFIN;Acc:ZDB-GENE-040426-1495])

HSP 1 Score: 145.206 bits (365), Expect = 3.684e-39
Identity = 97/323 (30.03%), Postives = 175/323 (54.18%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKL---TEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGD--AKL----IERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLE 1042
             ++ F ++++  ++ +++F++  + +      R++++ EVP++A++++++YNNTS I+D  L  R+ L P+  +P L EF +   P D++           D+D    +LK +  SR  K   P + +   +    +K      VYS  L W P+G QA  +++  +    +D+++  L P  EI ++   VK  G +HAKF PV+ A  R    ++LL P+ G  AL LQS F EGVI +++  A  G+  AK+    ++  ++    +EDLKD V++    N FI+ VES      P + ++  A++ ++EKCR YL  L+
Sbjct:   46 FEQNFRIDVVRMEDMEMEFDMVGVDAAIANAFRRILLAEVPTMAVEKVFIYNNTSIIQDEILAHRLGLIPIHADPRLFEFRN---PGDEEGT---------DIDTVQFQLK-VKCSRNPKA--PKDSSDPNELYINHK------VYSRHLRWVPLGSQADVYAEGSIRPVNDDILIALLRPGHEIDIMVHCVKGIGRDHAKFSPVATASYRLLPEIRLLVPVVGALALKLQSCFSEGVIGVEEVDACAGEKVAKVLNARLDTCSREVLRHEDLKDLVQLCRIRNHFIFSVEST--GALPPSVLVCEAIKVLMEKCRKYLNELD 345
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Yeast
Match: RPC40 (RNA polymerase subunit AC40; common to RNA polymerase I and III; predominant determinant targeting Ty1 integration upstream of Pol III-transcribed genes [Source:SGD;Acc:S000006314])

HSP 1 Score: 153.295 bits (386), Expect = 2.014e-42
Identity = 105/295 (35.59%), Postives = 154/295 (52.20%), Query Frame = 2 
Query:   89 SVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDP--LNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSD---VKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGV--ATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESV 952
            +V   K+ F VNI S D  +  F++ N+ +      R+++I+EVPSVA + +Y +NNTS I+D  L  RI L P+ V+PD+L +  S  P+D+K  F  +  ++  L+V   +    +    +  TDP  L  NA               VY+ DL + P G Q+  F+D   V    D++L +L P +EI L A  +   G +HAKF PVS A  R    + +L PI G SA   Q  FP GVI I +G   A V DA+  +  ++    YE+  DKV++G   N FI+ VES 
Sbjct:   32 NVEKFKKDFEVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNLPDDEK--FTDENTIVLSLNVKCTR----NPDAPKGSTDPKELYNNA--------------HVYARDLKFEPQGRQSTTFADCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARK-DTVSREVLRYEEFADKVKLGRVRNHFIFNVESA 305
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Nematostella
Match: EDO35589 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL38])

HSP 1 Score: 100.138 bits (248), Expect = 4.482e-23
Identity = 88/331 (26.59%), Postives = 152/331 (45.92%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKF--SDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPV--SAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVF-------------IWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLE 1042
             +EKF +NI       ++F++  + +      R++++ EVP++AI++++LYNNTS I+D  L  R+ L P+  +P L  +       D++++ D+   L+F+L V   K                NKNA +      +   +  V +D L W P   QA KF   D++   +V+       +E+ +   AVK  G +HAKF PV  S A  R    + LL P     A  L + F  GVIK+K    TV +      TN        L + + + + EN+              +  + ++RP+      ++  A++ +I KCR ++  L+
Sbjct:   42 FEEKFKINITRLTPSDMEFDMIGIDASVANAFRRILLAEVPTMAIEKVFLYNNTSIIQDEVLAHRLGLIPIHADPRLFNYKKQ---GDEEAQDDT--TLVFELKVKCIK----------------NKNAPKDATDPDELYINSKVTTDHLKWIPTPQQAQKFGPQDIRPLSNVVF--FFTLQELDIKMHAVKGVGKDHAKFSPVGKSTASYRLLPEITLLKPCEDELADKLAACFSPGVIKVK----TVNEKN---HTNDQNVGLRSLCNIISVYISENIIRNEFVEKNYTNVSVESIGALRPE-----VLVCEAIKVLISKCRQFISELD 337
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Nematostella
Match: EDO36595 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI64])

HSP 1 Score: 50.0618 bits (118), Expect = 8.506e-7
Identity = 52/201 (25.87%), Postives = 89/201 (44.28%), Query Frame = 2 
Query:  116 NVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPV--DVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSA 712
            +V IL   +E +KF I          LR++ I E P++AID + + NNTS + D  +  R+ L P+  D   D + F S +   D   EF     + F LDV        D++R     D ++ N   + +P     R+              D + ++ +    +D+++ +L   +E+ L A A K +   HAK+ P + 
Sbjct:    8 SVKILELTDENVKFIIEKTGMSMANGLRRIFIAETPTIAIDWVQIENNTSVLHDEFIAHRLGLVPLTSDEVVDRMTF-SRDCTCD---EFCDDCSIEFTLDVKCTD----DSTRHVTTQDLISTNP--RCVPVTSRNRE--------------DDSREYME---QDDILIVKLRKGQELKLRAFAKKGFAKEHAKWNPTAG 181
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Medaka
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:101171140])

HSP 1 Score: 134.806 bits (338), Expect = 1.147e-34
Identity = 88/328 (26.83%), Postives = 170/328 (51.83%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEF--YSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQ 1057
             ++ F ++++  D   ++F++  + +      R++++ EVP++AI+++++YNNTS ++D  L  R+ L P+  +P L E+   + E+   + SE D+    +           KI  SR        N  A ++     +   +  VYS D+ W P+G+QA  F+D ++    +D+++ +L P +E+ ++   VK  G +HAKF PV+ A  R    + L+  + G  A  L+  F  GVI ++    K VA V +++L +  ++    ++DLK+ V++G   + FI+ +ES      PA  ++  A++ ++ KC+  L  L     Q
Sbjct:   46 FQKNFRIDVVHLDENNIEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIVQDEVLAHRLGLVPIKADPRLFEYKNIAEEFGEQEASEIDTIQLQL-----------KIKCSR--------NPRASKESSDPRELYLNHIVYSKDINWVPLGNQADVFADSRIGAVHDDIVIAQLRPGQELDVVMHCVKGIGKDHAKFSPVATASYRLLPDITLMEQVEGEKAERLKRCFSRGVIDLEDVRGKKVAKVVNSRL-DTCSREVLRHKDLKNLVKLGRVRDHFIFTIEST--GSLPADVLMQEAIKVLMAKCQMLLNELSSAGTQ 351
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Medaka
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:101171140])

HSP 1 Score: 132.494 bits (332), Expect = 7.478e-34
Identity = 88/326 (26.99%), Postives = 171/326 (52.45%), Query Frame = 2 
Query:  101 LKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLT---EDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIK----KGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQ 1057
             ++ F ++++  D   ++F++  + +      R++++ EVP++AI+++++YNNTS ++D  L  R+ L P+  +P L E+ + E    + SE D+    +           KI  SR  + +   + +  E +L       +  VYS D+ W P+G+QA  F+D ++    +D+++ +L P +E+ ++   VK  G +HAKF PV+ A  R    + L+  + G  A  L+  F  GVI ++    K VA V +++L +  ++    ++DLK+ V++G   + FI+ +ES      PA  ++  A++ ++ KC+  L  L     Q
Sbjct:   43 FQKNFRIDVVHLDENNIEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIVQDEVLAHRLGLVPIKADPRLFEYKNIE---QEASEIDTIQLQL-----------KIKCSRNPRASKE-SSDPRELYL-------NHIVYSKDINWVPLGNQADVFADSRIGAVHDDIVIAQLRPGQELDVVMHCVKGIGKDHAKFSPVATASYRLLPDITLMEQVEGEKAERLKRCFSRGVIDLEDVRGKKVAKVVNSRL-DTCSREVLRHKDLKNLVKLGRVRDHFIFTIEST--GSLPADVLMQEAIKVLMAKCQMLLNELSSAGTQ 343
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Medaka
Match: polr2c (RNA polymerase II subunit C [Source:NCBI gene;Acc:101167955])

HSP 1 Score: 49.2914 bits (116), Expect = 4.192e-6
Identity = 50/200 (25.00%), Postives = 88/200 (44.00%), Query Frame = 2 
Query:  119 VNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLI-FDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAA 715
            V I    +E +KF I N       ++R++ ++EVP++AID + +  N+S + D  +  R+ L P+  + D+++    +Y  D   E     C +   LDV   +    D +R     D L+ N   + +P     RD                    +D    +D++L +L   +E+ L A A K +G  HAK+ P +  
Sbjct:    9 VKITELTDENVKFVIENTDLAVANSIRRVFMSEVPTIAIDWIQIDANSSVLHDEFIAHRVGLIPL-TSDDIVD--KMQYSRDCTCEDFCPECSVELTLDVRCTE----DQTRHVTSRDLLSNNP--RVIPVTSRSRDNDP-----------------NDYVEQDDILLVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGV 182
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Planmine SMEST
Match: SMESG000066290.1 (SMESG000066290.1)

HSP 1 Score: 949.503 bits (2453), Expect = 0.000e+0
Identity = 455/466 (97.64%), Postives = 461/466 (98.93%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSFHLNDVNME 1441
            EEH NQYKPSKHC GS+N LKE+FN+NI SCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSC+EDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSK+CLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLI LAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQ+CGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSFHLNDVNME
Sbjct:    7 EEHCNQYKPSKHCVGSLNSLKEQFNINITSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCVEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKSCLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIGLAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQICGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSFHLNDVNME 472
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Planmine SMEST
Match: SMESG000066290.1 (SMESG000066290.1)

HSP 1 Score: 899.427 bits (2323), Expect = 0.000e+0
Identity = 432/438 (98.63%), Postives = 436/438 (99.54%), Query Frame = 2 
Query:  128 LSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSFHLNDVNME 1441
            + CDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSC+EDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSK+CLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLI LAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQ+CGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSFHLNDVNME
Sbjct:   15 IVCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCVEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKSCLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIGLAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQICGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYLFGGKRAACAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQFITESVEMKLSSFHLNDVNME 452
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Planmine SMEST
Match: SMESG000050677.1 (SMESG000050677.1)

HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0
Identity = 323/400 (80.75%), Postives = 334/400 (83.50%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYL 1243
            EEHSNQYKPSKHCA             ++   +  L+F I+                                         LRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTE V+LNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGR+AHTLKLLS ITGNSALTLQSLFP+GVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIG DENVFIW+VESVRPKHQPAA+ILVSALRSMIEKCRFY GNLEYITEQQ+IEQ  NTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYL
Sbjct:    5 EEHSNQYKPSKHCA-------------VVKTRSLNLRFTIY----------------------------------------PLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEGVLLNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRQAHTLKLLSSITGNSALTLQSLFPKGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGFDENVFIWEVESVRPKHQPAAEILVSALRSMIEKCRFYQGNLEYITEQQQIEQVKNTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYL 351
[Close]
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Planmine SMEST
Match: SMESG000050681.1 (SMESG000050681.1)

HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 320/400 (80.00%), Postives = 333/400 (83.25%), Query Frame = 2 
Query:   44 EEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSDFHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTLQSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVFIWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGNTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYL 1243
            +EHSNQYKPSKHCA             ++   +  L+F I+                                         LRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKL+KIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTE V+LNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGR+AHTLKLLS ITGNSALTLQSLFP+GVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIG DENVFIW+VESVRPKHQPAA+ILVSA RSMIEKCRFY GNLEYITEQQ+IEQ  NTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYL
Sbjct:    5 DEHSNQYKPSKHCA-------------VVITRSLNLRFTIY----------------------------------------PLRIALTPVDVNPDLLEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLQKIDTSRFEKFTDPLNKNAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEGVLLNRLMPDEEIFLIALAVKNYGHNHAKFIPVSAAHGRQAHTLKLLSSITGNSALTLQSLFPKGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGFDENVFIWEVESVRPKHQPAAEILVSAFRSMIEKCRFYQGNLEYITEQQQIEQVKNTNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYLMNYL 351
The following BLAST results are available for this feature:
BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
POLR1C7.934e-3126.63RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
POLR1C4.001e-2927.01RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
POLR1C4.858e-2726.74RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
POLR1C2.009e-2626.98RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
POLR1C2.009e-2626.98RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rpac-402.341e-3930.97RNA Polymerase I/III (A/C) shared subunit [Source... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG37564.030e-3631.99gene:FBgn0031657 transcript:FBtr0078994[more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
polr1c2.000e-3630.22RNA polymerase I and III subunit C [Source:ZFIN;Ac... [more]
polr1c6.433e-1332.63RNA polymerase I and III subunit C [Source:ZFIN;Ac... [more]
polr2c2.017e-625.50polymerase (RNA) II (DNA directed) polypeptide C [... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
POLR1C2.016e-3029.31RNA polymerase I and III subunit C [Source:NCBI ge... [more]
POLR1C1.465e-2928.77RNA polymerase I and III subunit C [Source:NCBI ge... [more]
ttll11.273e-625.50tubulin tyrosine ligase like 1 [Source:Xenbase;Acc... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Polr1c6.791e-3427.69polymerase (RNA) I polypeptide C [Source:MGI Symbo... [more]
Polr1c3.020e-2628.11polymerase (RNA) I polypeptide C [Source:MGI Symbo... [more]
Polr1c2.187e-1725.76polymerase (RNA) I polypeptide C [Source:MGI Symbo... [more]
Polr1c5.219e-725.52polymerase (RNA) I polypeptide C [Source:MGI Symbo... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P07703|RPAC1_YEAST1.398e-4035.59DNA-directed RNA polymerases I and III subunit RPA... [more]
sp|O94616|RPAC1_SCHPO2.072e-3730.61DNA-directed RNA polymerases I and III subunit RPA... [more]
sp|P52432|RPAC1_MOUSE4.750e-3327.69DNA-directed RNA polymerases I and III subunit RPA... [more]
sp|O15160|RPAC1_HUMAN3.810e-3026.63DNA-directed RNA polymerases I and III subunit RPA... [more]
sp|Q32L22|RPAC1_BOVIN1.158e-2926.63DNA-directed RNA polymerases I and III subunit RPA... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
H2KQJ06.551e-5131.37DNA-directed RNA polymerases I and III subunit RPA... [more]
A0A5J4NFJ81.052e-4832.59DNA-directed RNA polymerases I and III subunit RPA... [more]
W6UQQ31.985e-4830.26DNA-directed RNA polymerases I and III subunit RPA... [more]
A0A068WEZ72.245e-4830.47DNA directed RNA polymerases I and III subunit OS=... [more]
A0A074ZE825.799e-4830.53RPOLD domain-containing protein OS=Opisthorchis vi... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
polr1c1.780e-3630.43RNA polymerase I and III subunit C [Source:NCBI ge... [more]
polr1c1.922e-2125.79RNA polymerase I and III subunit C [Source:NCBI ge... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
polr1c3.684e-3930.03RNA polymerase I and III subunit C [Source:ZFIN;Ac... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
RPC402.014e-4235.59RNA polymerase subunit AC40; common to RNA polymer... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO355894.482e-2326.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365958.506e-725.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
polr1c1.147e-3426.83RNA polymerase I and III subunit C [Source:NCBI ge... [more]
polr1c7.478e-3426.99RNA polymerase I and III subunit C [Source:NCBI ge... [more]
polr2c4.192e-625.00RNA polymerase II subunit C [Source:NCBI gene;Acc:... [more]
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BLAST of DNA-directed RNA polymerases I and III subunit RPAC1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000066290.10.000e+097.64SMESG000066290.1[more]
SMESG000066290.10.000e+098.63SMESG000066290.1[more]
SMESG000050677.10.000e+080.75SMESG000050677.1[more]
SMESG000050681.10.000e+080.00SMESG000050681.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031697 ID=SMED30031697|Name=DNA-directed RNA polymerases I and III subunit RPAC1|organism=Schmidtea mediterranea sexual|type=transcript|length=1685bp
TTGGAGGATATGATTTTTAATTATAGTTTAGATGTCTATTATTGAAGAAC
ATTCCAATCAATACAAGCCTTCAAAACATTGTGCGGGTAGTGTAAATGAT
CTCAAAGAAAAATTTAATGTAAATATTCTCAGTTGTGATAACGAGAAGCT
TAAATTTGAGATTCACAATTTACCCAGTGATTTTCATTGCACATTACGAA
AGCTTATTATAAATGAAGTGCCATCAGTTGCAATTGATCGACTATATTTA
TACAATAATACAAGTTGTATCGAAGATTCTGATTTGCAGCTGCGTATAGC
TCTTACTCCAGTTGATGTTAATCCAGATTTGTTAGAATTTTATTCATCAG
AATATCCAAACGATGACAAATCAGAATTTGATTCAAAAGCGTGTTTGATA
TTTGATTTGGATGTTAATTACAACAAACTGAAAAAGATTGATACCAGTCG
ATTCGAAAAGTTTACAGATCCTCTTAATAAAAATGCAGTAGAGAAATTTT
TACCAACTTATAAAGAACGTCGAGATCGTACAGTGTACAGTGATGATTTA
GTATGGCGCCCAATCGGAGATCAAGCATTGAAATTTTCCGATGTAAAATT
AACTGAAGACGTTATATTGAATAGATTGATGCCAGATGAGGAAATATTTC
TCATTGCGCTAGCAGTGAAAAATTACGGACATAACCATGCAAAATTCATA
CCTGTCAGTGCAGCACATGGCCGCCGAGCTCACACTCTCAAGCTATTATC
GCCAATTACCGGAAATAGCGCACTTACATTACAGAGTTTATTCCCGGAAG
GCGTAATTAAGATCAAGAAAGGAGTCGCCACTGTCGGCGATGCAAAGCTG
ATCGAAAGAACGAATAAAAATTTCTATGAATATGAAGATCTGAAAGACAA
AGTCGAAATCGGATTGGATGAAAACGTTTTCATTTGGCAGGTGGAATCAG
TACGGCCTAAGCACCAGCCTGCAGCTCAGATCCTAGTCAGTGCGTTGCGC
AGCATGATTGAGAAATGCCGATTCTATCTGGGTAACCTTGAATATATCAC
CGAGCAGCAGCGGATTGAGCAAGGGGGAAACACCAATCGCAAACTCGATT
ACAAATCATATGCGAGACAAGTTTGCGGCAAAACTTGTTTCATCGAGAAA
GATCTTAATGTAGGAAACGGATCGGCTTTCTATCGGTTTCACGGCGAATC
GGATACTTTGGGCGTCTCTCTTGTTTATTTGATGAATTATCTGTTCGGCG
GCAAACGGGCCGCTTGTGCTTATCATAGGGTTGAGCTAGGCATTGAGCTG
TTGGTGCGTGTTTCTAACGGAACCACTGGCGAACAGATCTTGACCGAGGG
ATTTACTGCCATGTTGTCATATTTCCAGTTCATCACGGAATCAGTGGAAA
TGAAACTGTCCAGCTTTCACCTGAATGATGTCAATATGGAATAAAATGTT
ATCTGTTTGAATTTTTGCAGATATTCACAAGCTTGCTTATTATTGATTTC
AGTCGATTGGTTTGCTTTACGCTGAGATATCCGTTAGGGAAATTCGTTTT
TTGGATCACCGTACTCGTTGGTAACAATTTGGAATCTTACGTACATCTAA
CTTTTATTATTATTTATATACAGTAAAAAATCAATATTATTACATTTATT
CACTTTATATTTAAAAGGAATTAATTAAAAATTAC
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protein sequence of SMED30031697-orf-1

>SMED30031697-orf-1 ID=SMED30031697-orf-1|Name=SMED30031697-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=471bp
MSIIEEHSNQYKPSKHCAGSVNDLKEKFNVNILSCDNEKLKFEIHNLPSD
FHCTLRKLIINEVPSVAIDRLYLYNNTSCIEDSDLQLRIALTPVDVNPDL
LEFYSSEYPNDDKSEFDSKACLIFDLDVNYNKLKKIDTSRFEKFTDPLNK
NAVEKFLPTYKERRDRTVYSDDLVWRPIGDQALKFSDVKLTEDVILNRLM
PDEEIFLIALAVKNYGHNHAKFIPVSAAHGRRAHTLKLLSPITGNSALTL
QSLFPEGVIKIKKGVATVGDAKLIERTNKNFYEYEDLKDKVEIGLDENVF
IWQVESVRPKHQPAAQILVSALRSMIEKCRFYLGNLEYITEQQRIEQGGN
TNRKLDYKSYARQVCGKTCFIEKDLNVGNGSAFYRFHGESDTLGVSLVYL
MNYLFGGKRAACAYHRVELGIELLVRVSNGTTGEQILTEGFTAMLSYFQF
ITESVEMKLSSFHLNDVNME*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036643RNApol_insert_sf
IPR033901RNAPI/II_AC40
IPR036603RBP11-like
IPR011263DNA-dir_RNA_pol_RpoA/D/Rpb3
IPR011262DNA-dir_RNA_pol_insert
IPR009025RBP11-like_dimer
Vocabulary: molecular function
TermDefinition
GO:0003899DNA-directed 5'-3' RNA polymerase activity
GO:0046983protein dimerization activity
Vocabulary: biological process
TermDefinition
GO:0006351transcription, DNA-templated
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR011263DNA-directed RNA polymerase, RpoA/D/Rpb3-typeSMARTSM00662rpoldneu2coord: 41..338
e-value: 2.8E-7
score: 26.2
IPR011263DNA-directed RNA polymerase, RpoA/D/Rpb3-typePFAMPF01193RNA_pol_Lcoord: 44..331
e-value: 2.0E-5
score: 23.9
IPR036643DNA-directed RNA polymerase, insert domain superfamilyGENE3DG3DSA:2.170.120.12coord: 67..222
e-value: 1.8E-53
score: 183.5
IPR036643DNA-directed RNA polymerase, insert domain superfamilySUPERFAMILYSSF56553Insert subdomain of RNA polymerase alpha subunitcoord: 66..226
NoneNo IPR availableGENE3DG3DSA:3.30.1360.270coord: 30..330
e-value: 1.8E-53
score: 183.5
NoneNo IPR availablePANTHERPTHR11800DNA-DIRECTED RNA POLYMERASEcoord: 12..334
IPR033901DNA-directed RNA polymerases I and III subunit AC40PANTHERPTHR11800:SF13DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1coord: 12..334
IPR036603RNA polymerase, RBP11-like subunitSUPERFAMILYSSF55257RBP11-like subunits of RNA polymerasecoord: 28..339