Trimethylguanosine synthase

Overview
NameTrimethylguanosine synthase
Smed IDSMED30031688
Length (bp)1387
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Trimethylguanosine synthase (SMED30031688) t-SNE clustered cells

Violin plots show distribution of expression levels for Trimethylguanosine synthase (SMED30031688) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Trimethylguanosine synthase (SMED30031688) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Trimethylguanosine synthase (SMED30031688) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30031688

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30031688SMESG000001975.1 SmedASXL_015510SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30031688SMESG000001975.1 SmedASXL_015510SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30031688SMESG000001975.1 dd_Smed_v4_9949_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Human
Match: TGS1 (trimethylguanosine synthase 1 [Source:HGNC Symbol;Acc:HGNC:17843])

HSP 1 Score: 152.14 bits (383), Expect = 4.376e-39
Identity = 91/228 (39.91%), Postives = 124/228 (54.39%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSE---DYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+     + KYW+QRY LF RFD GIKLD+E W+SVT E IA+  A   S     D V+D FCG GGNTIQFA     V+A+DIDP+K+ L R+N  VYG+ + K+  +  DF               L +    DVVFLSPPWGG +Y T +T    T  S D  ++   ++     ++  FLPRN++   + +   P   +EI ++        N K+K ITA F
Sbjct:  636 PEIAAVPELAKYWAQRYRLFSRFDDGIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIAD-KIEFICGDFL-------------LLASFLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSKKITNNIVY-FLPRNADIDQVASLAGPGGQVEIEQN------FLNNKLKTITAYF 842
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Celegans
Match: T08G11.4 (pep chromosome:WBcel235:I:8902749:8905534:-1 gene:WBGene00011631.1 transcript:T08G11.4b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08G11.4)

HSP 1 Score: 133.65 bits (335), Expect = 5.633e-34
Identity = 84/228 (36.84%), Postives = 116/228 (50.88%), Query Frame = 3 
Query:  666 NDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVL--DGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT----DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRR 1331
            ND  + KY+ QRY LF R D GI +D+E W+SVT E IA+  A+     +  +  D F G GGN IQFA +  HV+A+D+DP++++  R N  VYGV E  +  +  DF+  A  +     L      P +D VFLSPPWGG +YL     D A       ID   +   +    P  I  FLPRN++ S L       ++   I+  A      N KIK IT  + +
Sbjct:  270 NDPEISKYYYQRYRLFSRLDQGIIMDREGWFSVTPEAIAEHIADRVVRNNVSVVVDAFTGVGGNAIQFALRGAHVIAIDMDPVRLKCARENARVYGV-ENYIDFICADFFDVAATWQADKKL-----APKVDAVFLSPPWGGPSYLKAKEFDLATGCCPNGID---IFDVSLKICPN-IAYFLPRNTKVSQLVELATKAKSRMEIEQSA-----LNSKIKTITVYYGK 482
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Celegans
Match: T08G11.4 (pep chromosome:WBcel235:I:8902749:8904979:-1 gene:WBGene00011631.1 transcript:T08G11.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08G11.4)

HSP 1 Score: 133.65 bits (335), Expect = 5.633e-34
Identity = 84/228 (36.84%), Postives = 116/228 (50.88%), Query Frame = 3 
Query:  666 NDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVL--DGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT----DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRR 1331
            ND  + KY+ QRY LF R D GI +D+E W+SVT E IA+  A+     +  +  D F G GGN IQFA +  HV+A+D+DP++++  R N  VYGV E  +  +  DF+  A  +     L      P +D VFLSPPWGG +YL     D A       ID   +   +    P  I  FLPRN++ S L       ++   I+  A      N KIK IT  + +
Sbjct:  270 NDPEISKYYYQRYRLFSRLDQGIIMDREGWFSVTPEAIAEHIADRVVRNNVSVVVDAFTGVGGNAIQFALRGAHVIAIDMDPVRLKCARENARVYGV-ENYIDFICADFFDVAATWQADKKL-----APKVDAVFLSPPWGGPSYLKAKEFDLATGCCPNGID---IFDVSLKICPN-IAYFLPRNTKVSQLVELATKAKSRMEIEQSA-----LNSKIKTITVYYGK 482
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Celegans
Match: T08G11.4 (pep chromosome:WBcel235:I:8902747:8905534:-1 gene:WBGene00011631.1 transcript:T08G11.4a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08G11.4)

HSP 1 Score: 133.265 bits (334), Expect = 1.729e-33
Identity = 84/228 (36.84%), Postives = 116/228 (50.88%), Query Frame = 3 
Query:  666 NDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVL--DGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT----DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRR 1331
            ND  + KY+ QRY LF R D GI +D+E W+SVT E IA+  A+     +  +  D F G GGN IQFA +  HV+A+D+DP++++  R N  VYGV E  +  +  DF+  A  +     L      P +D VFLSPPWGG +YL     D A       ID   +   +    P  I  FLPRN++ S L       ++   I+  A      N KIK IT  + +
Sbjct:  341 NDPEISKYYYQRYRLFSRLDQGIIMDREGWFSVTPEAIAEHIADRVVRNNVSVVVDAFTGVGGNAIQFALRGAHVIAIDMDPVRLKCARENARVYGV-ENYIDFICADFFDVAATWQADKKL-----APKVDAVFLSPPWGGPSYLKAKEFDLATGCCPNGID---IFDVSLKICPN-IAYFLPRNTKVSQLVELATKAKSRMEIEQSA-----LNSKIKTITVYYGK 553
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Celegans
Match: T08G11.4 (pep chromosome:WBcel235:I:8902747:8905466:-1 gene:WBGene00011631.1 transcript:T08G11.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08G11.4)

HSP 1 Score: 133.265 bits (334), Expect = 1.729e-33
Identity = 84/228 (36.84%), Postives = 116/228 (50.88%), Query Frame = 3 
Query:  666 NDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVL--DGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT----DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRR 1331
            ND  + KY+ QRY LF R D GI +D+E W+SVT E IA+  A+     +  +  D F G GGN IQFA +  HV+A+D+DP++++  R N  VYGV E  +  +  DF+  A  +     L      P +D VFLSPPWGG +YL     D A       ID   +   +    P  I  FLPRN++ S L       ++   I+  A      N KIK IT  + +
Sbjct:  341 NDPEISKYYYQRYRLFSRLDQGIIMDREGWFSVTPEAIAEHIADRVVRNNVSVVVDAFTGVGGNAIQFALRGAHVIAIDMDPVRLKCARENARVYGV-ENYIDFICADFFDVAATWQADKKL-----APKVDAVFLSPPWGGPSYLKAKEFDLATGCCPNGID---IFDVSLKICPN-IAYFLPRNTKVSQLVELATKAKSRMEIEQSA-----LNSKIKTITVYYGK 553
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Fly
Match: Tgs1 (gene:FBgn0266195 transcript:FBtr0343791)

HSP 1 Score: 144.05 bits (362), Expect = 1.072e-37
Identity = 80/188 (42.55%), Postives = 108/188 (57.45%), Query Frame = 3 
Query:  666 NDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDT-------SKLLGCARMFKPKVILIFLPRNS 1208
            ++N+M KYW +R+ LF RFD GI+LD+ESW+SVT E IAKQ A   +  D ++D FCG GGN IQFA  C  V+A+DID  K+ + +HN  +YGV   K+  +  DF  FA          S    P  +VVFLSPPWGG +Y     +    + I+T       S+L+  +R     V   FLPRN+
Sbjct:  252 DNNKMVKYWVKRFSLFSRFDQGIRLDRESWFSVTPEKIAKQTARRLAC-DVIVDAFCGCGGNAIQFANTCGRVIAVDIDAEKLAMAKHNAGIYGVAH-KIEFIHADFLQFA---------ASTKLRP--NVVFLSPPWGGPDY-----QKQATFDIETGLLPVGASQLMQLSRSLASDVAF-FLPRNA 420
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Zebrafish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7])

HSP 1 Score: 158.688 bits (400), Expect = 1.514e-41
Identity = 86/228 (37.72%), Postives = 125/228 (54.82%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQA---ELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+  +  + KYW+QRY LF RFD GIKLD E W+SVT E IA+  A   + C + + ++D FCG GGN IQFA   + V+ +DIDP+++ L +HN  VYGV E ++  ++ DF   A                  D+VFLSPPWGG  YLT D     T  + D  ++   ++M    ++  FLPRN++   + +   P   +E+ ++        N K+K ITA F
Sbjct:  589 PEIAAEPELAKYWAQRYRLFSRFDEGIKLDHEGWFSVTPEKIAEHIALRVQDCFNTELIIDAFCGVGGNAIQFALTGKRVIGIDIDPVRLALAQHNAAVYGV-EQRIDFLQGDFLQLAPHLRG-------------DMVFLSPPWGGPEYLTADVFNIQTMMTPDGFEIFRLSKMISDNIVY-FLPRNADMEQIASLAGPGGKVEVEQN------FLNNKLKTITAYF 795
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Zebrafish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7])

HSP 1 Score: 119.013 bits (297), Expect = 4.650e-31
Identity = 67/196 (34.18%), Postives = 101/196 (51.53%), Query Frame = 3 
Query:  750 SWYSVTAEYIAKQQA---ELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
             W+SVT E IA+  A   + C + + ++D FCG GGN IQFA   + V+ +DIDP+++ L +HN  VYGV E ++  ++ DF   A                  D+VFLSPPWGG  YLT D     T  + D  ++   ++M    ++  FLPRN++   + +   P   +E+       +   N K+K ITA F
Sbjct:    2 GWFSVTPEKIAEHIALRVQDCFNTELIIDAFCGVGGNAIQFALTGKRVIGIDIDPVRLALAQHNAAVYGV-EQRIDFLQGDFLQLAPHLRG-------------DMVFLSPPWGGPEYLTADVFNIQTMMTPDGFEIFRLSKMISDNIVY-FLPRNADMEQIASLAGPGGKVEV------EQNFLNNKLKTITAYF 176
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Xenopus
Match: TGS1 (ras-related and estrogen-regulated growth inhibitor-like protein [Source:Xenbase;Acc:XB-GENE-5824246])

HSP 1 Score: 147.132 bits (370), Expect = 2.431e-37
Identity = 83/228 (36.40%), Postives = 121/228 (53.07%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVT----AEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+     + KYW+QRY LF RFD GIKLD+E W+SVT    AE+IA +  + C     V+D FCG GGN IQFA     V+A+DIDP+K++  R+N  VYGV + ++  ++ DF   A                  D VFLSPPWGG +Y++          +D  ++   ++    K I+ FLPRN++   + +   P   +EI       +   N+K+K +T  F
Sbjct:  630 PEIAAVPHLAKYWAQRYRLFSRFDEGIKLDEEGWFSVTPEKIAEHIASRVRQSCDC-GVVVDAFCGVGGNAIQFAKAGNRVIAVDIDPVKLDFARNNAEVYGVTD-RIEFIRGDFMLLAQDLKA-------------DAVFLSPPWGGPDYVSAETFDIRTMCLDGFEVFRLSKQLT-KNIIYFLPRNTDVEQVASLAGPGGQVEI------EQNFLNKKLKTMTVYF 835
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Mouse
Match: Tgs1 (trimethylguanosine synthase 1 [Source:MGI Symbol;Acc:MGI:2151797])

HSP 1 Score: 151.754 bits (382), Expect = 4.060e-39
Identity = 92/230 (40.00%), Postives = 128/230 (55.65%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSE---DYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVI--DVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+ +   + KYW+QRY LF RFD GIKLDKE W+SVT E IA+  A   S     D V+D FCG GGNTIQFA   + V+A+DIDP+K++L R+N  VYG+ + K+  +  DF               L+  P +  DVVFLSPPWGG +Y T +T    T  S D  ++   ++     ++  FLPRN++   + +       +EI ++        N K+K ITA F
Sbjct:  628 PEIASVPELAKYWAQRYRLFSRFDDGIKLDKEGWFSVTPEKIAEHIAGRVSQAFRCDVVVDAFCGVGGNTIQFALTGKRVIAIDIDPVKIDLARNNAEVYGIAD-KIEFICGDF---------------LLLAPCLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSQKITNNIVY-FLPRNADIDQVASLAGLGGQVEIEQN------FLNNKLKTITAYF 834
[Close]
BLAST of Trimethylguanosine synthase vs. UniProt/SwissProt
Match: sp|P85107|TGS1_RAT (Trimethylguanosine synthase OS=Rattus norvegicus OX=10116 GN=Tgs1 PE=1 SV=1)

HSP 1 Score: 156.762 bits (395), Expect = 6.536e-40
Identity = 93/230 (40.43%), Postives = 128/230 (55.65%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSE---DYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVI--DVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+ +   + KYW+QRY LF RFD GIKLDKE W+SVT E IA+  A   S     D ++D FCG GGNTIQFA   + V+A+DIDP+K++L R+N  VYGV + K+  +  DF               L+  P +  DVVFLSPPWGG +Y T +T    T  S D  ++   ++     ++  FLPRN++   + +   P   +EI       +   N K+K ITA F
Sbjct:  630 PEIASVPELAKYWAQRYRLFSRFDDGIKLDKEGWFSVTPEKIAEHIAGRVSQSFNCDIIVDAFCGVGGNTIQFALTGKRVIAIDIDPVKIDLARNNAEVYGVAD-KIEFICGDF---------------LLLAPCLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSQKITNNIVY-FLPRNADVDQVASLAGPGGQVEI------EQNFLNNKLKTITAYF 836
[Close]
BLAST of Trimethylguanosine synthase vs. UniProt/SwissProt
Match: sp|Q96RS0|TGS1_HUMAN (Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3)

HSP 1 Score: 152.14 bits (383), Expect = 2.101e-38
Identity = 91/228 (39.91%), Postives = 124/228 (54.39%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSE---DYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+     + KYW+QRY LF RFD GIKLD+E W+SVT E IA+  A   S     D V+D FCG GGNTIQFA     V+A+DIDP+K+ L R+N  VYG+ + K+  +  DF               L +    DVVFLSPPWGG +Y T +T    T  S D  ++   ++     ++  FLPRN++   + +   P   +EI ++        N K+K ITA F
Sbjct:  636 PEIAAVPELAKYWAQRYRLFSRFDDGIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIAD-KIEFICGDFL-------------LLASFLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSKKITNNIVY-FLPRNADIDQVASLAGPGGQVEIEQN------FLNNKLKTITAYF 842
[Close]
BLAST of Trimethylguanosine synthase vs. UniProt/SwissProt
Match: sp|Q923W1|TGS1_MOUSE (Trimethylguanosine synthase OS=Mus musculus OX=10090 GN=Tgs1 PE=1 SV=2)

HSP 1 Score: 151.754 bits (382), Expect = 2.840e-38
Identity = 92/230 (40.00%), Postives = 128/230 (55.65%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSE---DYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVI--DVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+ +   + KYW+QRY LF RFD GIKLDKE W+SVT E IA+  A   S     D V+D FCG GGNTIQFA   + V+A+DIDP+K++L R+N  VYG+ + K+  +  DF               L+  P +  DVVFLSPPWGG +Y T +T    T  S D  ++   ++     ++  FLPRN++   + +       +EI ++        N K+K ITA F
Sbjct:  628 PEIASVPELAKYWAQRYRLFSRFDDGIKLDKEGWFSVTPEKIAEHIAGRVSQAFRCDVVVDAFCGVGGNTIQFALTGKRVIAIDIDPVKIDLARNNAEVYGIAD-KIEFICGDF---------------LLLAPCLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSQKITNNIVY-FLPRNADIDQVASLAGLGGQVEIEQN------FLNNKLKTITAYF 834
[Close]
BLAST of Trimethylguanosine synthase vs. UniProt/SwissProt
Match: sp|Q09814|TGS1_SCHPO (Trimethylguanosine synthase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=tgs1 PE=1 SV=3)

HSP 1 Score: 125.946 bits (315), Expect = 3.692e-32
Identity = 75/190 (39.47%), Postives = 102/190 (53.68%), Query Frame = 3 
Query:  684 KYWSQRYDLFERFDMGIKLDKESWYSVTAE----YIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTD---YSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTF 1232
            KYW+ RY+LF RFD GI LD +SWYSVT E     IAK   +    E  ++D F G GGNTIQFA  C  V++++IDPIK+ + +HN  +YG+  +++T ++ D          +    SL        VF+SPPWGG +Y   T  S  D   Y+ D   L   A    P V   FLPRN++   L  +
Sbjct:   28 KYWNNRYNLFSRFDEGIWLDYQSWYSVTPEKVAVAIAKSVVDFIQPE-LIIDAFSGCGGNTIQFAKYC-PVISIEIDPIKIAMAKHNLEIYGIPSSRVTFIQGDVLDTFKSLQFAKDYRSL--------VFMSPPWGGPSYSGKTVYSLNDLNPYAFDV--LFKEATRISPYV-AAFLPRNTDVKELAAY 204
[Close]
BLAST of Trimethylguanosine synthase vs. UniProt/SwissProt
Match: sp|Q12052|TGS1_YEAST (Trimethylguanosine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TGS1 PE=1 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 5.969e-20
Identity = 69/214 (32.24%), Postives = 101/214 (47.20%), Query Frame = 3 
Query:  669 DNRMFKYWSQRYDLFERFD-MGIKLDKESWYSVTAEYIAKQQAELCSS----EDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTS-KLLGCARMFK------PKVILIFLPRNSEESHL----RTFLEPNETLEII 1262
            + ++FKYW  R  LF + D   I +  E W+SVT E IA   A    +     + +LD FCG GGNTIQFA +  +V  +D     +  T  N   YGVD+ ++ + +  +    ++   S            D VF SPPWGG  YL +       Y ++   K +G  +M K      P VI+ FLPRNS+ + L    R  L P    +++
Sbjct:   46 NGKLFKYWKNRRRLFSKIDSASIYMTDELWFSVTPERIACFLANFVKACMPNAERILDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYGVDD-RIWLKRGSWKKLVSKQKLSKI--------KYDCVFGSPPWGGPEYLRNDV-----YDLEQHLKPMGITKMLKSFLKLSPNVIM-FLPRNSDLNQLSRATRKVLGPFAKCKVL 244
[Close]
BLAST of Trimethylguanosine synthase vs. TrEMBL
Match: V4AVC3 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_113851 PE=4 SV=1)

HSP 1 Score: 169.474 bits (428), Expect = 1.023e-45
Identity = 95/230 (41.30%), Postives = 131/230 (56.96%), Query Frame = 3 
Query:  657 ELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVI--DVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFK-----PKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            ++++D  + KYW QRY LF RFD GI+LD+ESW+SVT E I++  AE C   D ++DGFCGAGGNTIQFA  C  V+A+DIDP+K+EL R+N  VYGV E ++  +  DFY                 MP +  DVVFLSPPWGG  YL     ++ +Y ++    L    +FK      + I  F+PRN+    L         +EI ++      + N K+K ITA +
Sbjct:   50 DIQDDKELCKYWYQRYRLFSRFDEGIQLDRESWFSVTPEKISEHIAERCQC-DVIVDGFCGAGGNTIQFALYCERVIAIDIDPVKIELARNNAKVYGV-EDRIEFIVGDFYK---------------VMPSLQADVVFLSPPWGGPEYL-----NNKNYDLNNMACLNAFDIFKISQKITQNIAFFVPRNTNIDQLTVLAGSGGKVEIEQN------ILNSKLKTITAYY 251
[Close]
BLAST of Trimethylguanosine synthase vs. TrEMBL
Match: A7SAF9 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g243959 PE=4 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 1.226e-45
Identity = 91/225 (40.44%), Postives = 121/225 (53.78%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNY-LTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            P+   D    KYW+QRY LF RFD GIK+DKE WYSVT E IA+  AE C   D ++D FCG GGN IQFA+ C  V+A+DIDP+K++  RHN  +YGV + ++  +  DF     Q                DV+FLSPPWGG  Y   D     T  S+D  +L   A+   P  I  F+PRN     L +   P   +EI ++        N+K+K +TA +
Sbjct:    2 PQEEADPEFAKYWAQRYRLFSRFDEGIKMDKEGWYSVTPERIAEHIAERCRC-DLIVDAFCGVGGNAIQFAFTCERVIAIDIDPVKIDCARHNAEIYGVAD-RIEFVLGDFRQIVPQLKA-------------DVIFLSPPWGGPGYACADVFDIQTMISLDGFELYETAKRVTPN-IAYFMPRNVNMEQLTSLAGPAGKVEIEQN------FVNKKLKTVTAYY 204
[Close]
BLAST of Trimethylguanosine synthase vs. TrEMBL
Match: A0A1Q3F523 (Putative prip OS=Culex tarsalis OX=7177 PE=4 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 1.035e-44
Identity = 96/231 (41.56%), Postives = 130/231 (56.28%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTS-------KLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+ ND  + KYW +R+ LF  FD GIKLD+ESW+SVT E +A   AE C S D V+DGFCG GGN+IQ A+ C  V+A+DIDP K+E+ +HN  VYGV + ++  +  DF + A++                D VFLSPPWGG +YL D       Y ++TS       +L+  AR   P V L +LPRNS    L     PN  +EI       +   + K+ A+TA +
Sbjct:  805 PEIANDKSLLKYWYKRFSLFSLFDAGIKLDRESWFSVTPEKVAAHTAERCRS-DLVVDGFCGCGGNSIQLAFTCNQVIAIDIDPKKIEMAKHNAAVYGVAD-RIEFIVGDFLALADRLRA-------------DAVFLSPPWGGPSYLKDEV-----YDLETSLIPVPATELMRKARQISPNVAL-YLPRNSNTQQLTMLAGPNNAVEI------EQNFLDRKLIALTAYY 1008
[Close]
BLAST of Trimethylguanosine synthase vs. TrEMBL
Match: A0A1Q3F5C9 (Putative prip OS=Culex tarsalis OX=7177 PE=4 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 1.065e-44
Identity = 96/231 (41.56%), Postives = 130/231 (56.28%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTS-------KLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+ ND  + KYW +R+ LF  FD GIKLD+ESW+SVT E +A   AE C S D V+DGFCG GGN+IQ A+ C  V+A+DIDP K+E+ +HN  VYGV + ++  +  DF + A++                D VFLSPPWGG +YL D       Y ++TS       +L+  AR   P V L +LPRNS    L     PN  +EI       +   + K+ A+TA +
Sbjct:  805 PEIANDKSLLKYWYKRFSLFSLFDAGIKLDRESWFSVTPEKVAAHTAERCRS-DLVVDGFCGCGGNSIQLAFTCNQVIAIDIDPKKIEMAKHNAAVYGVAD-RIEFIVGDFLALADRLRA-------------DAVFLSPPWGGPSYLKDEV-----YDLETSLIPVPATELMRKARQISPNVAL-YLPRNSNTQQLTMLAGPNNAVEI------EQNFLDRKLIALTAYY 1008
[Close]
BLAST of Trimethylguanosine synthase vs. TrEMBL
Match: A0A1Q3F5M2 (Putative prip OS=Culex tarsalis OX=7177 PE=4 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 1.179e-44
Identity = 96/231 (41.56%), Postives = 130/231 (56.28%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTS-------KLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+ ND  + KYW +R+ LF  FD GIKLD+ESW+SVT E +A   AE C S D V+DGFCG GGN+IQ A+ C  V+A+DIDP K+E+ +HN  VYGV + ++  +  DF + A++                D VFLSPPWGG +YL D       Y ++TS       +L+  AR   P V L +LPRNS    L     PN  +EI       +   + K+ A+TA +
Sbjct:  803 PEIANDKSLLKYWYKRFSLFSLFDAGIKLDRESWFSVTPEKVAAHTAERCRS-DLVVDGFCGCGGNSIQLAFTCNQVIAIDIDPKKIEMAKHNAAVYGVAD-RIEFIVGDFLALADRLRA-------------DAVFLSPPWGGPSYLKDEV-----YDLETSLIPVPATELMRKARQISPNVAL-YLPRNSNTQQLTMLAGPNNAVEI------EQNFLDRKLIALTAYY 1006
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Cavefish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7])

HSP 1 Score: 157.147 bits (396), Expect = 5.171e-41
Identity = 88/228 (38.60%), Postives = 125/228 (54.82%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAK---QQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+  +  + KYW+QRY LF RFD G+KLD E W+SVT E IA+   Q+ +  S    ++D FCG GGN IQFA   + V+A+DIDP+++ L +HN  VYGV +  +  ++ DF   A +                DVVFLSPPWGG  YL+ D     T  S D  ++   +RM   + I+ FLPRN++   +     P   +E+ ++        N K+K ITA F
Sbjct:  598 PEIAAEPELAKYWAQRYRLFSRFDEGVKLDHEGWFSVTPEKIAEHIAQRVQETSGLQLIVDAFCGVGGNAIQFALTGKRVMAVDIDPVRLALAQHNAEVYGVAQL-IDFIQGDFLQVAPRLRA-------------DVVFLSPPWGGPEYLSADVFDIKTMMSPDGFEIFRLSRMIS-ENIVYFLPRNADMEQIAALAGPGGKVEVEQN------FLNNKLKTITAYF 804
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Cavefish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7])

HSP 1 Score: 156.377 bits (394), Expect = 6.827e-41
Identity = 88/233 (37.77%), Postives = 124/233 (53.22%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAK---QQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT------DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+  +  + KYW+QRY LF RFD G+KLD E W+SVT E IA+   Q+ +  S    ++D FCG GGN IQFA   + V+A+DIDP+++ L +HN  VYGV +  +  ++ DF   A +                DVVFLSPPWGG  YL+       T  S   Y   T+  LG   +   + I+ FLPRN++   +     P   +E+ ++        N K+K ITA F
Sbjct:  556 PEIAAEPELAKYWAQRYRLFSRFDEGVKLDHEGWFSVTPEKIAEHIAQRVQETSGLQLIVDAFCGVGGNAIQFALTGKRVMAVDIDPVRLALAQHNAEVYGVAQL-IDFIQGDFLQVAPRLRA-------------DVVFLSPPWGGPEYLSADVFDIKTMMSPDGYPFSTAHQLG---VMISENIVYFLPRNADMEQIAALAGPGGKVEVEQN------FLNNKLKTITAYF 765
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Cavefish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7])

HSP 1 Score: 156.762 bits (395), Expect = 8.594e-41
Identity = 88/228 (38.60%), Postives = 125/228 (54.82%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAK---QQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+  +  + KYW+QRY LF RFD G+KLD E W+SVT E IA+   Q+ +  S    ++D FCG GGN IQFA   + V+A+DIDP+++ L +HN  VYGV +  +  ++ DF   A +                DVVFLSPPWGG  YL+ D     T  S D  ++   +RM   + I+ FLPRN++   +     P   +E+ ++        N K+K ITA F
Sbjct:  657 PEIAAEPELAKYWAQRYRLFSRFDEGVKLDHEGWFSVTPEKIAEHIAQRVQETSGLQLIVDAFCGVGGNAIQFALTGKRVMAVDIDPVRLALAQHNAEVYGVAQL-IDFIQGDFLQVAPRLRA-------------DVVFLSPPWGGPEYLSADVFDIKTMMSPDGFEIFRLSRMIS-ENIVYFLPRNADMEQIAALAGPGGKVEVEQN------FLNNKLKTITAYF 863
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Cavefish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7])

HSP 1 Score: 146.362 bits (368), Expect = 2.307e-37
Identity = 88/248 (35.48%), Postives = 126/248 (50.81%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLD--------------------KESWYSVTAEYIAK---QQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            PE+  +  + KYW+QRY LF RFD G+KLD                    +E W+SVT E IA+   Q+ +  S    ++D FCG GGN IQFA   + V+A+DIDP+++ L +HN  VYGV +  +  ++ DF   A +                DVVFLSPPWGG  YL+ D     T  S D  ++   +RM   + I+ FLPRN++   +     P   +E+ ++        N K+K ITA F
Sbjct:  625 PEIAAEPELAKYWAQRYRLFSRFDEGVKLDHERNADVRPETSSTAEKEREREGWFSVTPEKIAEHIAQRVQETSGLQLIVDAFCGVGGNAIQFALTGKRVMAVDIDPVRLALAQHNAEVYGVAQL-IDFIQGDFLQVAPRLRA-------------DVVFLSPPWGGPEYLSADVFDIKTMMSPDGFEIFRLSRMIS-ENIVYFLPRNADMEQIAALAGPGGKVEVEQN------FLNNKLKTITAYF 851
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Yeast
Match: TGS1 (Trimethyl guanosine synthase, conserved nucleolar methyl transferase; converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for nucleolar assembly and splicing of meiotic pre-mRNAs; interacts with Swm2p, which may confer substrate specificity on Tgs1p [Source:SGD;Acc:S000006078])

HSP 1 Score: 93.9745 bits (232), Expect = 8.596e-22
Identity = 69/214 (32.24%), Postives = 101/214 (47.20%), Query Frame = 3 
Query:  669 DNRMFKYWSQRYDLFERFD-MGIKLDKESWYSVTAEYIAKQQAELCSS----EDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTS-KLLGCARMFK------PKVILIFLPRNSEESHL----RTFLEPNETLEII 1262
            + ++FKYW  R  LF + D   I +  E W+SVT E IA   A    +     + +LD FCG GGNTIQFA +  +V  +D     +  T  N   YGVD+ ++ + +  +    ++   S            D VF SPPWGG  YL +       Y ++   K +G  +M K      P VI+ FLPRNS+ + L    R  L P    +++
Sbjct:   46 NGKLFKYWKNRRRLFSKIDSASIYMTDELWFSVTPERIACFLANFVKACMPNAERILDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYGVDD-RIWLKRGSWKKLVSKQKLSKI--------KYDCVFGSPPWGGPEYLRNDV-----YDLEQHLKPMGITKMLKSFLKLSPNVIM-FLPRNSDLNQLSRATRKVLGPFAKCKVL 244
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Nematostella
Match: EDO39303 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAF9])

HSP 1 Score: 167.548 bits (423), Expect = 1.696e-49
Identity = 91/225 (40.44%), Postives = 121/225 (53.78%), Query Frame = 3 
Query:  654 PELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNY-LTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            P+   D    KYW+QRY LF RFD GIK+DKE WYSVT E IA+  AE C   D ++D FCG GGN IQFA+ C  V+A+DIDP+K++  RHN  +YGV + ++  +  DF     Q                DV+FLSPPWGG  Y   D     T  S+D  +L   A+   P  I  F+PRN     L +   P   +EI ++        N+K+K +TA +
Sbjct:    2 PQEEADPEFAKYWAQRYRLFSRFDEGIKMDKEGWYSVTPERIAEHIAERCRC-DLIVDAFCGVGGNAIQFAFTCERVIAIDIDPVKIDCARHNAEIYGVAD-RIEFVLGDFRQIVPQLKA-------------DVIFLSPPWGGPGYACADVFDIQTMISLDGFELYETAKRVTPN-IAYFMPRNVNMEQLTSLAGPAGKVEIEQN------FVNKKLKTVTAYY 204
[Close]
BLAST of Trimethylguanosine synthase vs. Ensembl Medaka
Match: lyn (trimethylguanosine synthase 1 [Source:NCBI gene;Acc:101155635])

HSP 1 Score: 154.836 bits (390), Expect = 2.952e-40
Identity = 88/228 (38.60%), Postives = 124/228 (54.39%), Query Frame = 3 
Query:  657 ELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQA----ELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLT-DTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIF 1325
            E+  D+ + KYW+QRY LF RFD GI+LD+E W+SVT E IA   A        + + V+D FCG GGNTIQFA   + VLA+DID +K++L RHN  VYGV + ++  ++ DF   A +                DVVFLSPPWGG NYLT +     T    D  ++   A+     ++  FLPRN+    + +   P   +E+ ++        N K+K +TA F
Sbjct:  591 EVEADSELAKYWAQRYRLFSRFDEGIRLDREGWFSVTPERIAAHIALRVKHSFPTSELVIDAFCGVGGNTIQFALTGKRVLAVDIDVVKLDLARHNAEVYGVAQ-RIDFLQGDFLQLAPRLRG-------------DVVFLSPPWGGPNYLTAEVFDIRTMMEPDGFEIFSRAKQISDNIVY-FLPRNANMDQVVSLAGPGGMVEVEQN------FLNNKLKTVTAYF 797
[Close]
BLAST of Trimethylguanosine synthase vs. Planmine SMEST
Match: SMESG000001975.1 (SMESG000001975.1)

HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0
Identity = 416/421 (98.81%), Postives = 418/421 (99.29%), Query Frame = 3 
Query:   78 MNLSNDFADIENELMKRKI-KRNLKRHKKLNESSLNNPFLSKRAQIIQSNKEIFXXXXXXXXXXXXXEIMHVEKKKFSDSSKNDVIIIDSDNELENIDYLTSPPECQVLQKVDYLKFEIKXXXXXXXXXXXXXXXXXXXXQDIIHLDGDLPIKSDCETSAEIIQDXXXXXXXXXXXXXXXXXXXXXXXXFPNNPELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRRNL 1337
            MNLSNDFADIENELMKRKI KRNLKRHKKLNESSLNNPFLSKRAQIIQSNKEIFDTLSDISTDDSDLEIMHVEKKKF+DSSKNDVIIIDSDNELENIDYLTSPPECQVLQKVDYLKFEIKNSPIHDSSNSSSADSSRNENQDIIHLDGDLPIKSDCETSAEIIQDKNEQNVSSVKSNNKRKRKRKSDKRFPNNPELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAE CSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFAN YSTSGTLNSLVTMP+IDVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRRNL
Sbjct:    1 MNLSNDFADIENELMKRKIIKRNLKRHKKLNESSLNNPFLSKRAQIIQSNKEIFDTLSDISTDDSDLEIMHVEKKKFTDSSKNDVIIIDSDNELENIDYLTSPPECQVLQKVDYLKFEIKNSPIHDSSNSSSADSSRNENQDIIHLDGDLPIKSDCETSAEIIQDKNEQNVSSVKSNNKRKRKRKSDKRFPNNPELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAEFCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANLYSTSGTLNSLVTMPLIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRRNL 421
[Close]
BLAST of Trimethylguanosine synthase vs. Planmine SMEST
Match: SMESG000001975.1 (SMESG000001975.1)

HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0
Identity = 272/275 (98.91%), Postives = 273/275 (99.27%), Query Frame = 3 
Query:  513 DGDLPIKSDCETSAEIIQDXXXXXXXXXXXXXXXXXXXXXXXXFPNNPELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRRNL 1337
            DGDLPIKSDCETSAEIIQDKNEQNVSSVKSNNKRKRKRKSDKRFPNNPELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAE CSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFAN YSTSGTLNSLVTMP+IDVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRRNL
Sbjct:   52 DGDLPIKSDCETSAEIIQDKNEQNVSSVKSNNKRKRKRKSDKRFPNNPELRNDNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAEFCSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANLYSTSGTLNSLVTMPLIDVVFLSPPWGGQNYLTDTAKSSTDYSIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAITAIFRRNL 326

HSP 2 Score: 96.6709 bits (239), Expect = 5.165e-22
Identity = 50/52 (96.15%), Postives = 51/52 (98.08%), Query Frame = 3 
Query:   78 MNLSNDFADIENELMKRKI-KRNLKRHKKLNESSLNNPFLSKRAQIIQSNKE 230
            MNLSNDFADIENELMKRKI KRNLKRHKKLNESSLNNPFLSKRAQIIQSNK+
Sbjct:    1 MNLSNDFADIENELMKRKIIKRNLKRHKKLNESSLNNPFLSKRAQIIQSNKD 52
[Close]
BLAST of Trimethylguanosine synthase vs. Planmine SMEST
Match: SMESG000027459.1 (SMESG000027459.1)

HSP 1 Score: 113.62 bits (283), Expect = 8.005e-27
Identity = 82/227 (36.12%), Postives = 115/227 (50.66%), Query Frame = 3 
Query:  669 DNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAEL-------CSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPV-IDVVFLSPPWGGQNYLTDTAKSSTDYSI---DTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAIT 1316
            +N M KY+ QRY  F+RFD GI LD+ESWYSVT   +A+Q A          S+   ++D FCGAGGN I+FA     VLA+D+D  K++L  HN  +Y VD+ ++  +  DFY       +    + L  +   +  V +SPPWGG  YL         Y+I   D   L+  A    P V   FLPR+S    + ++L  N          +   L N K+KA+T
Sbjct:  303 ENPMNKYYFQRYRYFDRFDQGILLDEESWYSVTPGALAEQVAHRYHQVFSESSNNPIMIDAFCGAGGNAIRFAEYGFIVLAIDMDIKKLKLLMHNAAIYEVDK-RIVPVCCDFYKLQEWIKSEDCFDELRDLFFSVLAVHISPPWGGPEYLEMDV-----YNIGFMDFGTLMKTALNLSPNVS-CFLPRHSNCQQIVSWLTLNSISNCNSVEIEQNCLQN-KVKALT 521
[Close]
BLAST of Trimethylguanosine synthase vs. Planmine SMEST
Match: SMESG000027459.1 (SMESG000027459.1)

HSP 1 Score: 98.2117 bits (243), Expect = 8.897e-22
Identity = 77/227 (33.92%), Postives = 109/227 (48.02%), Query Frame = 3 
Query:  669 DNRMFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAEL-------CSSEDYVLDGFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMKDDFYSFANQYSTSGTLNSLVTMPV-IDVVFLSPPWGGQNYLTDTAKSSTDYSI---DTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAKYKQLANEKIKAIT 1316
            +N M KY+ QRY  F+RFD GI LD+ESWYSVT   +A+Q A          S+   ++D FCGAG            VLA+D+D  K++L  HN  +Y VD+ ++  +  DFY       +    + L  +   +  V +SPPWGG  YL         Y+I   D   L+  A    P V   FLPR+S    + ++L  N          +   L N K+KA+T
Sbjct:  303 ENPMNKYYFQRYRYFDRFDQGILLDEESWYSVTPGALAEQVAHRYHQVFSESSNNPIMIDAFCGAG------------VLAIDMDIKKLKLLMHNAAIYEVDK-RIVPVCCDFYKLQEWIKSEDCFDELRDLFFSVLAVHISPPWGGPEYLEMDV-----YNIGFMDFGTLMKTALNLSPNVS-CFLPRHSNCQQIVSWLTLNSISNCNSVEIEQNCLQN-KVKALT 509
The following BLAST results are available for this feature:
BLAST of Trimethylguanosine synthase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TGS14.376e-3939.91trimethylguanosine synthase 1 [Source:HGNC Symbol;... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
T08G11.45.633e-3436.84pep chromosome:WBcel235:I:8902749:8905534:-1 gene:... [more]
T08G11.45.633e-3436.84pep chromosome:WBcel235:I:8902749:8904979:-1 gene:... [more]
T08G11.41.729e-3336.84pep chromosome:WBcel235:I:8902747:8905534:-1 gene:... [more]
T08G11.41.729e-3336.84pep chromosome:WBcel235:I:8902747:8905466:-1 gene:... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Tgs11.072e-3742.55gene:FBgn0266195 transcript:FBtr0343791[more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lyn1.514e-4137.72LYN proto-oncogene, Src family tyrosine kinase [So... [more]
lyn4.650e-3134.18LYN proto-oncogene, Src family tyrosine kinase [So... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
TGS12.431e-3736.40ras-related and estrogen-regulated growth inhibito... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Tgs14.060e-3940.00trimethylguanosine synthase 1 [Source:MGI Symbol;A... [more]
back to top
BLAST of Trimethylguanosine synthase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P85107|TGS1_RAT6.536e-4040.43Trimethylguanosine synthase OS=Rattus norvegicus O... [more]
sp|Q96RS0|TGS1_HUMAN2.101e-3839.91Trimethylguanosine synthase OS=Homo sapiens OX=960... [more]
sp|Q923W1|TGS1_MOUSE2.840e-3840.00Trimethylguanosine synthase OS=Mus musculus OX=100... [more]
sp|Q09814|TGS1_SCHPO3.692e-3239.47Trimethylguanosine synthase OS=Schizosaccharomyces... [more]
sp|Q12052|TGS1_YEAST5.969e-2032.24Trimethylguanosine synthase OS=Saccharomyces cerev... [more]
back to top
BLAST of Trimethylguanosine synthase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V4AVC31.023e-4541.30Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A7SAF91.226e-4540.44Predicted protein OS=Nematostella vectensis OX=453... [more]
A0A1Q3F5231.035e-4441.56Putative prip OS=Culex tarsalis OX=7177 PE=4 SV=1[more]
A0A1Q3F5C91.065e-4441.56Putative prip OS=Culex tarsalis OX=7177 PE=4 SV=1[more]
A0A1Q3F5M21.179e-4441.56Putative prip OS=Culex tarsalis OX=7177 PE=4 SV=1[more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
lyn5.171e-4138.60LYN proto-oncogene, Src family tyrosine kinase [So... [more]
lyn6.827e-4137.77LYN proto-oncogene, Src family tyrosine kinase [So... [more]
lyn8.594e-4138.60LYN proto-oncogene, Src family tyrosine kinase [So... [more]
lyn2.307e-3735.48LYN proto-oncogene, Src family tyrosine kinase [So... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
TGS18.596e-2232.24Trimethyl guanosine synthase, conserved nucleolar ... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO393031.696e-4940.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
lyn2.952e-4038.60trimethylguanosine synthase 1 [Source:NCBI gene;Ac... [more]
back to top
BLAST of Trimethylguanosine synthase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000001975.10.000e+098.81SMESG000001975.1[more]
SMESG000001975.15.165e-2298.91SMESG000001975.1[more]
SMESG000027459.18.005e-2736.12SMESG000027459.1[more]
SMESG000027459.18.897e-2233.92SMESG000027459.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031688 ID=SMED30031688|Name=Trimethylguanosine synthase|organism=Schmidtea mediterranea sexual|type=transcript|length=1387bp
TTAATAGACAAACTAAAAACTCAAAATATACTTTGTTTATTTATTCATTA
TTTTCTTTTTAAACTTTAAAGGCAGTCATGAATTTATCAAATGATTTTGC
GGATATTGAAAATGAATTAATGAAGAGGAAAATCAAGCGAAATTTAAAAA
GACATAAAAAATTAAACGAAAGTTCATTAAACAATCCATTTCTATCTAAA
AGAGCTCAAATAATTCAAAGTAACAAAGAGATATTTGATACTCTGAGCGA
TATATCAACAGACGATTCAGATTTAGAAATTATGCATGTCGAGAAGAAAA
AATTTTCTGATTCAAGTAAAAATGATGTAATTATAATAGATAGTGACAAT
GAATTGGAAAATATTGATTATTTAACATCCCCACCTGAATGTCAAGTGTT
ACAAAAAGTTGATTATTTAAAATTTGAAATCAAAAACTCTCCGATTCATG
ATAGTTCTAATTCATCATCTGCTGATTCATCCAGAAATGAAAATCAAGAT
ATTATTCATTTAGATGGTGACTTGCCAATCAAAAGCGATTGTGAAACTTC
TGCAGAAATTATTCAAGACAAAAATGAGCAAAACGTATCCAGTGTAAAAT
CAAACAACAAACGGAAAAGAAAACGAAAATCAGACAAGAGATTTCCAAAC
AATCCAGAATTACGAAATGATAATCGCATGTTTAAATACTGGTCGCAACG
ATATGATCTGTTCGAACGCTTCGATATGGGCATAAAACTTGACAAAGAAT
CGTGGTACAGCGTCACTGCCGAGTACATTGCTAAGCAACAGGCGGAGTTA
TGCAGTAGCGAAGATTATGTTCTCGATGGGTTTTGTGGCGCCGGTGGCAA
TACTATTCAATTCGCTTATAAATGTCGCCATGTTCTAGCATTGGATATTG
ATCCTATCAAAGTAGAACTTACGAGACACAATTGTCATGTTTACGGCGTT
GATGAGACTAAATTAACAATTATGAAAGATGATTTTTATTCATTTGCTAA
CCAATACAGCACATCTGGTACTCTTAACAGCCTTGTGACAATGCCTGTAA
TCGACGTCGTGTTCCTCTCTCCTCCCTGGGGAGGCCAGAATTATCTTACA
GATACGGCAAAATCTTCAACAGATTACTCAATCGATACGAGCAAGTTGTT
AGGTTGTGCCAGAATGTTCAAGCCAAAAGTTATTTTGATCTTCCTGCCTA
GAAATAGCGAGGAATCTCACTTGCGCACATTCCTGGAGCCCAATGAGACT
CTGGAAATTATCAAGCACGGTGCTAAATATAAACAGCTCGCCAATGAGAA
AATCAAAGCCATTACGGCAATTTTTAGGCGAAATTTGTAAATATCCGATC
CCGATTTGGATAAATATATCGATTGAGCTGTTGAAAA
back to top

protein sequence of SMED30031688-orf-1

>SMED30031688-orf-1 ID=SMED30031688-orf-1|Name=SMED30031688-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=421bp
MNLSNDFADIENELMKRKIKRNLKRHKKLNESSLNNPFLSKRAQIIQSNK
EIFDTLSDISTDDSDLEIMHVEKKKFSDSSKNDVIIIDSDNELENIDYLT
SPPECQVLQKVDYLKFEIKNSPIHDSSNSSSADSSRNENQDIIHLDGDLP
IKSDCETSAEIIQDKNEQNVSSVKSNNKRKRKRKSDKRFPNNPELRNDNR
MFKYWSQRYDLFERFDMGIKLDKESWYSVTAEYIAKQQAELCSSEDYVLD
GFCGAGGNTIQFAYKCRHVLALDIDPIKVELTRHNCHVYGVDETKLTIMK
DDFYSFANQYSTSGTLNSLVTMPVIDVVFLSPPWGGQNYLTDTAKSSTDY
SIDTSKLLGCARMFKPKVILIFLPRNSEESHLRTFLEPNETLEIIKHGAK
YKQLANEKIKAITAIFRRNL*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR029063SAM-dependent_MTases
IPR019012RNA_cap_Gua-N2-MeTrfase
Vocabulary: biological process
TermDefinition
GO:0001510RNA methylation
GO:00094527-methylguanosine RNA capping
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019012RNA cap guanine-N2 methyltransferasePFAMPF09445Methyltransf_15coord: 179..318
e-value: 1.4E-27
score: 96.3
NoneNo IPR availableGENE3DG3DSA:3.40.50.150coord: 124..352
e-value: 2.4E-56
score: 192.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 94..125
NoneNo IPR availablePANTHERPTHR14741S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATEDcoord: 21..348
NoneNo IPR availablePANTHERPTHR14741:SF32TRIMETHYLGUANOSINE SYNTHASEcoord: 21..348
NoneNo IPR availableCDDcd02440AdoMet_MTasescoord: 180..217
e-value: 0.00107631
score: 36.2539
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILYSSF53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 131..307