Acetylcholine receptor subunit alpha-like

Overview
NameAcetylcholine receptor subunit alpha-like
Smed IDSMED30031662
Length (bp)1678
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Acetylcholine receptor subunit alpha-like (SMED30031662) t-SNE clustered cells

Violin plots show distribution of expression levels for Acetylcholine receptor subunit alpha-like (SMED30031662) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Acetylcholine receptor subunit alpha-like (SMED30031662) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Acetylcholine receptor subunit alpha-like (SMED30031662) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Homology
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Human
Match: CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960])

HSP 1 Score: 183.726 bits (465), Expect = 1.264e-50
Identity = 119/371 (32.08%), Postives = 201/371 (54.18%), Query Frame = 1 
Query:  103 SSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            +S      PVS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q C L F SW+      ++  ++A D  G+      NGEW++V  P   +   Y+   +       Y +VTF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   39 ASVRPAPGPVSLQGEFQRKLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA-DISGY----IPNGEWDLVGIPGKRSERFYECCKEP------YPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 390
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Human
Match: CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960])

HSP 1 Score: 181.03 bits (458), Expect = 6.824e-50
Identity = 117/362 (32.32%), Postives = 198/362 (54.70%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q C L F SW+      ++  ++A D  G+      NGEW++V  P   +   Y+   +       Y +VTF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   19 VSLQGEFQRKLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA-DISGY----IPNGEWDLVGIPGKRSERFYECCKEP------YPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Human
Match: AC243734.1 (cholinergic receptor nicotinic alpha 7 subunit [Source:NCBI gene;Acc:1139])

HSP 1 Score: 181.03 bits (458), Expect = 6.824e-50
Identity = 117/362 (32.32%), Postives = 198/362 (54.70%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q C L F SW+      ++  ++A D  G+      NGEW++V  P   +   Y+   +       Y +VTF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   19 VSLQGEFQRKLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA-DISGY----IPNGEWDLVGIPGKRSERFYECCKEP------YPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Human
Match: AC254952.1 (cholinergic receptor nicotinic alpha 7 subunit [Source:NCBI gene;Acc:1139])

HSP 1 Score: 179.489 bits (454), Expect = 2.426e-49
Identity = 116/362 (32.04%), Postives = 198/362 (54.70%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+D+  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q C L F SW+      ++  ++A D  G+      NGEW++V  P   +   Y+   +       Y +VTF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   19 VSLQGEFQRKLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDQKRQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA-DISGY----IPNGEWDLVGIPGKRSERFYECCKEP------YPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Human
Match: AC254952.1 (cholinergic receptor nicotinic alpha 7 subunit [Source:NCBI gene;Acc:1139])

HSP 1 Score: 179.489 bits (454), Expect = 2.426e-49
Identity = 116/362 (32.04%), Postives = 198/362 (54.70%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+D+  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q C L F SW+      ++  ++A D  G+      NGEW++V  P   +   Y+   +       Y +VTF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   19 VSLQGEFQRKLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDQKRQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA-DISGY----IPNGEWDLVGIPGKRSERFYECCKEP------YPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Celegans
Match: acr-19 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:B3WFZ2])

HSP 1 Score: 160.614 bits (405), Expect = 1.651e-42
Identity = 113/366 (30.87%), Postives = 191/366 (52.19%), Query Frame = 1 
Query:   43 MLFKFGIGVFVLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDA---SIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMP--KFLK 1125
            M  +F IG+     + RV ++ +++ +                L   L + YN LA PV +      V + +   Q+ D+DE  Q++  +VW+ MSW D  LTWDP +F  + ++ LP   I+ PD++ Y S+   F+     +P + A +   G V     A+++S C +DI  FP+DTQ C + F SW        + N T   A      ++K   NGEWE++   +  ++  Y+   +       Y +VTF ++++R+  +    L+ PC+L+  ++ L+F LP + GEK+NL VTI +S+ VF+++V+E +P+TSD +P + ++F   +  V  SV+ T I LN   +S +   P  KFLK
Sbjct:    1 MRRRFEIGIAFFFALFRVIWTGDHERR----------------LYAKLAENYNKLARPVRNESEAVVVLLGMDYQQILDIDEKHQIMNSNVWLRMSWTDHYLTWDPSEFGNIKEVRLPINNIWKPDVLLYNSVDQQFDST---WPVN-AVVLYTGNVTWIPPAIIRSSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLINTTISPA------TYK--PNGEWELLGLTSQRSIFFYECCPEP------YYDVTFTVSIRRRTLYYGFNLLLPCMLISSLALLSFTLPADCGEKLNLGVTIFMSLCVFMIMVAEAMPQTSDALPLIQIYFSCIMFQVGASVVATVIALNFHHRSPEQYKPMNKFLK 332
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Celegans
Match: acr-19 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:B3WFZ2])

HSP 1 Score: 158.303 bits (399), Expect = 9.322e-42
Identity = 106/319 (33.23%), Postives = 175/319 (54.86%), Query Frame = 1 
Query:  184 LKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDA---SIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMP--KFLK 1125
            L + YN LA PV +      V + +   Q+ D+DE  Q++  +VW+ MSW D  LTWDP +F  + ++ LP   I+ PD++ Y S+   F+     +P + A +   G V     A+++S C +DI  FP+DTQ C + F SW        + N T   A      ++K   NGEWE++   +  ++  Y+   +       Y +VTF ++++R+  +    L+ PC+L+  ++ L+F LP + GEK+NL VTI +S+ VF+++V+E +P+TSD +P + ++F   +  V  SV+ T I LN   +S +   P  KFLK
Sbjct:   38 LAENYNKLARPVRNESEAVVVLLGMDYQQILDIDEKHQIMNSNVWLRMSWTDHYLTWDPSEFGNIKEVRLPINNIWKPDVLLYNSVDQQFDST---WPVN-AVVLYTGNVTWIPPAIIRSSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLINTTISPA------TYK--PNGEWELLGLTSQRSIFFYECCPEP------YYDVTFTVSIRRRTLYYGFNLLLPCMLISSLALLSFTLPADCGEKLNLGVTIFMSLCVFMIMVAEAMPQTSDALPLIQIYFSCIMFQVGASVVATVIALNFHHRSPEQYKPMNKFLK 338
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Celegans
Match: acr-11 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:P91197])

HSP 1 Score: 155.221 bits (391), Expect = 2.914e-41
Identity = 108/351 (30.77%), Postives = 181/351 (51.57%), Query Frame = 1 
Query:  184 LKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAG--EIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNAS----NGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSRFLCLHHKTHNKFRSGSANSKDNND 1215
            L +GYNPL  PV ++     V + ++L Q+ D+DE  Q+++++ W+  +WFD  L W+P  + G+  I  P     I+ PD++ Y S   +F+       +S       G V      +LK  C++D+  FP+D Q C + F SW       ++   D  D+ G    + S    NGEW+V+   A   +S YK   +       Y  V + L ++R+  +    LI P +L+  ++ L F+ P ++GEK+ L VTILL+++ FL +VSE  P TS+ +P +G+FF   + +V  SV+ T +VLN+  +S D  +M   ++R+L      L   +   ++   AN  D+ D
Sbjct:   33 LLKGYNPLERPVQNSSQPLEVKIKLFLQQILDVDEKNQIVSVNAWLSYTWFDHKLQWEPKKYGGIQDIRFPGSSDHIWKPDVLLYNSAAEDFDSTF----KSNLLTYHTGTVVWIPPGVLKFVCQLDVTWFPFDDQVCEMKFGSWTFHGYAIDLQIDD--DTNGTQSMDLSTYLVNGEWQVISTNAKRVVSYYKCCPEP------YPTVNYYLHIRRRTLYYGFNLIIPSLLISLMAILGFMFPPDAGEKITLEVTILLAIVFFLSMVSEMTPPTSEAVPLIGVFFSCCMLVVSASVVFTIVVLNLHFRSADSHEMNPLVRRVLLEFLPWLLFMSRPGYKFVKANVIDSTD 371
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Celegans
Match: unc-38 (Acetylcholine receptor subunit alpha-type unc-38 [Source:UniProtKB/Swiss-Prot;Acc:Q23022])

HSP 1 Score: 151.754 bits (382), Expect = 1.235e-39
Identity = 103/340 (30.29%), Postives = 178/340 (52.35%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAG-------DSKG--HSFKNASNG----------EWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVK-MPKFLKRI 1131
            L D L   YN    P         + + + L Q+ D+ E  Q++T  VW++ +W D  L+WDP ++ G++ + +P   I+ PD++ Y +   N+   +     + A +   G V     A+ KS C++D+R FP+D Q+C+L F SW    ++ ++   +         D KG   +   A +G          EW+++   A      Y     +S     Y +VT+ L L+RKP F  V L+FPCV + +++ L F LP +SGEKV L ++IL+++ +F LL++E IP TS  +P +G +   ++ +V LSV++T I LN+  ++     MP ++K++
Sbjct:   30 LYDDLMVNYNRHRRPSTSPNKPLTIKLKLRLSQIIDVHEIDQIMTCSVWLKQTWIDRKLSWDPVNYGGVNVLYVPYEMIWVPDIVLYNNADSNYNITI----STKATLHYTGEVTWEPPAIFKSMCQIDVRWFPFDEQQCHLKFGSWTFSENLLSVELNEPSLRYEEEIDEKGIIDNVTVAEDGIDLSDYYPSVEWDIMSRVAKRRAKNYPSCCPQSA----YIDVTYYLQLRRKPLFYTVNLVFPCVGISFLTILVFYLPSDSGEKVTLCISILVALTIFFLLLTEIIPATSITLPLIGKYLLFTMVMVTLSVVVTVISLNLHFRTPTTHLMPNWVKKV 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Celegans
Match: acr-9 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:Q18556])

HSP 1 Score: 149.443 bits (376), Expect = 9.517e-39
Identity = 108/360 (30.00%), Postives = 181/360 (50.28%), Query Frame = 1 
Query:   73 VLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLP--AGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNI-----TKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKR 1128
            VL H+    +SS ++++                L+  L+  Y+P   PV +      V + I+L Q+ D+DE  Q++T+  W+E  W D  L WDP ++ G+  I +P  A  I+ PD++ Y S   NF+     +P +     +  ++Q+    +LK  C++DI  FP+D Q C+L F SW    +  ++       K+  D          NGEW ++  PA +  + +    DE      Y  + F L +QR+  +  + LI P  L+  ++ L F LP ++GEK+ L +TILLSV  FL +V++  P TS+ +P +G FF   + +V  SV+ T +VLN+  +  +  +M  FL+ 
Sbjct:   14 VLFHLLTEVHSSADEYR----------------LLADLRHNYDPYERPVANASEPLVVSVKIYLQQILDVDEKNQVITLVAWIEYQWTDYKLKWDPSEYGGIKDIRIPGNANAIWKPDVLLYNSADENFDST---YPVNYVVSYTGDVLQV-PPGILKLSCKIDITYFPFDDQICHLKFGSWTYSGNFIDLRINGPEGKNISDEGIDVQYYVQNGEWNLLAVPARHETNIF----DEQP----YPSLFFYLIIQRRTLYYGLNLIIPSFLISLMTVLGFTLPPDAGEKITLEITILLSVCFFLSMVADMTPPTSEAVPLIGAFFSCCMLVVSASVVFTVLVLNLHNRKPETHEMSPFLRE 345
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Fly
Match: nAChRalpha4 (gene:FBgn0266347 transcript:FBtr0332872)

HSP 1 Score: 179.874 bits (455), Expect = 7.939e-50
Identity = 122/355 (34.37%), Postives = 193/355 (54.37%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNAS--------NGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNS---RFLCLHHKTHNKFRSGSANS 1200
            L D L   YN L  PV +      V + + L QL D++   Q++T ++W+E SW+D  L W+P ++ G+  + +P+  I+ PD++ Y +  GNFE  +     + A I S G+V+    A+ KS C +D+  FP+D Q C L F SW  D   F +  +   + +G +             + EW+++E PA     K+    DE      Y ++TF +T++RK  F  V +I PC+ + +++ LTF LP +SGEKV LS++IL+S+ VF LLV E IP TS  +P LG +   ++ LV +S+ +T +VLNV  +S    KM  ++KR+       FL +   T+N   S +AN 
Sbjct:   15 LYDDLLSNYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKEYGGVHMLHVPSDHIWRPDIVLYNNADGNFEVTL----ATKATIYSEGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDG--FKVDLRHMDEQQGSNVVAVGVDLSEFYMSVEWDILEVPAVRN-EKFYTCCDEP-----YLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSGEKVTLSISILISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISICVTVVVLNVHFRSPQTHKMAPWVKRVFIDFLPAFLFIKRPTYNFETSITANG 357
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Fly
Match: nAChRalpha4 (gene:FBgn0266347 transcript:FBtr0300118)

HSP 1 Score: 177.948 bits (450), Expect = 8.446e-49
Identity = 122/359 (33.98%), Postives = 194/359 (54.04%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNAS--------NGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNS---RFLCLHHKTHNKFRSGSANSKDNN 1212
            L D L   YN L  PV +      V + + L QL D++   Q++T ++W+E SW+D  L W+P ++ G+  + +P+  I+ PD++ Y +  GNFE  +     + A I S G+V+    A+ KS C +D+  FP+D Q C L F SW  D   F +  +   + +G +             + EW+++E PA     K+    DE      Y ++TF +T++RK  F  V +I PC+ + +++ LTF LP +SGEKV LS++IL+S+ VF LLV E IP TS  +P LG +   ++ LV +S+ +T +VLNV  +S    KM  ++KR+       FL +   T+N F +     KD +
Sbjct:   15 LYDDLLSNYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKEYGGVHMLHVPSDHIWRPDIVLYNNADGNFEVTL----ATKATIYSEGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDG--FKVDLRHMDEQQGSNVVAVGVDLSEFYMSVEWDILEVPAVRN-EKFYTCCDEP-----YLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSGEKVTLSISILISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISICVTVVVLNVHFRSPQTHKMAPWVKRVFIDFLPAFLFIKRPTYN-FETSKLLLKDTH 360
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0334916)

HSP 1 Score: 173.711 bits (439), Expect = 5.330e-47
Identity = 122/356 (34.27%), Postives = 192/356 (53.93%), Query Frame = 1 
Query:  118 HKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITK-KDAGDSK----GHSFKNAS-NGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRI---LNSRFLCL 1155
            H A   ++N   K +Y    D L   YN L  PV +N  +  V M + L QL D++   Q++T +VW+E  W D  L W+P D+ G+D + +P+  I+ PD++ Y +  GN+E  +     + A +   G V     A+ KSFC +D+  FP+D Q C + F SW  D  + ++   K   DS     G   ++   + EW+++  PA      Y    +       Y ++ F LTL+RK  F  V LI PCV + ++S L F LP +SGEK++L ++ILLS+ VF LL++E IP TS  +P LG +   ++ LV LSV++T  VLNV  +S    +M  +++R+   +  + LC+
Sbjct:   14 HFATGGLANPDAKRLY----DDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYNNADGNYEVTI----MTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEP------YLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVQRLFIQILPKLLCI 355
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0084619)

HSP 1 Score: 173.711 bits (439), Expect = 5.330e-47
Identity = 122/356 (34.27%), Postives = 192/356 (53.93%), Query Frame = 1 
Query:  118 HKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITK-KDAGDSK----GHSFKNAS-NGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRI---LNSRFLCL 1155
            H A   ++N   K +Y    D L   YN L  PV +N  +  V M + L QL D++   Q++T +VW+E  W D  L W+P D+ G+D + +P+  I+ PD++ Y +  GN+E  +     + A +   G V     A+ KSFC +D+  FP+D Q C + F SW  D  + ++   K   DS     G   ++   + EW+++  PA      Y    +       Y ++ F LTL+RK  F  V LI PCV + ++S L F LP +SGEK++L ++ILLS+ VF LL++E IP TS  +P LG +   ++ LV LSV++T  VLNV  +S    +M  +++R+   +  + LC+
Sbjct:   14 HFATGGLANPDAKRLY----DDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYNNADGNYEVTI----MTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEP------YLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVQRLFIQILPKLLCI 355
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0330310)

HSP 1 Score: 173.326 bits (438), Expect = 9.234e-47
Identity = 122/356 (34.27%), Postives = 192/356 (53.93%), Query Frame = 1 
Query:  118 HKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITK-KDAGDSK----GHSFKNAS-NGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRI---LNSRFLCL 1155
            H A   ++N   K +Y    D L   YN L  PV +N  +  V M + L QL D++   Q++T +VW+E  W D  L W+P D+ G+D + +P+  I+ PD++ Y +  GN+E  +     + A +   G V     A+ KSFC +D+  FP+D Q C + F SW  D  + ++   K   DS     G   ++   + EW+++  PA      Y    +       Y ++ F LTL+RK  F  V LI PCV + ++S L F LP +SGEK++L ++ILLS+ VF LL++E IP TS  +P LG +   ++ LV LSV++T  VLNV  +S    +M  +++R+   +  + LC+
Sbjct:   14 HFATGGLANPDAKRLY----DDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYNNADGNYEVTI----MTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEP------YLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVQRLFIQILPKLLCI 355
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Zebrafish
Match: chrna7 (cholinergic receptor, nicotinic, alpha 7 (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-3])

HSP 1 Score: 177.948 bits (450), Expect = 6.476e-49
Identity = 115/366 (31.42%), Postives = 195/366 (53.28%), Query Frame = 1 
Query:  118 HKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVG-EKSKDVKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            H   VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W+++ W+D  L W+  ++ G+  +  P  +I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D QRC+L F SW       ++   DA D  G+     +NGEW++VE P       Y    +       Y +VTF + ++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV+ T  VL       +  KMPK+ + +L    + FL +     +K R    N +
Sbjct:   16 HSPTVSLQGEHQRRLYRDLM----KDYNPLERPVFNDTHSLTVYFSMSLMQIMDVDEKNQVLTTNIWLQLYWYDYYLQWNASEYPGVTNVRFPDSQIWKPDILLYNSADERFDATF----HTNVLVNSSGACQYLPPGIFKSTCYIDVRWFPFDLQRCDLKFGSWTYGGWSLDLQMIDA-DITGY----IANGEWDLVEVPGRRNERFYDCCKEP------YPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPEGGKMPKWTRVVLLNWCAWFLRMKRPGEDKVRPACHNKQ 362
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Zebrafish
Match: chrna7 (cholinergic receptor, nicotinic, alpha 7 (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-3])

HSP 1 Score: 176.022 bits (445), Expect = 4.082e-48
Identity = 114/362 (31.49%), Postives = 194/362 (53.59%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVG-EKSKDVKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W+++ W+D  L W+  ++ G+  +  P  +I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D QRC+L F SW       ++   DA D  G+     +NGEW++VE P       Y    +       Y +VTF + ++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV+ T  VL       +  KMPK+ + +L    + FL +     +K R    N +
Sbjct:   19 VSLQGEHQRRLYRDLM----KDYNPLERPVFNDTHSLTVYFSMSLMQIMDVDEKNQVLTTNIWLQLYWYDYYLQWNASEYPGVTNVRFPDSQIWKPDILLYNSADERFDATF----HTNVLVNSSGACQYLPPGIFKSTCYIDVRWFPFDLQRCDLKFGSWTYGGWSLDLQMIDA-DITGY----IANGEWDLVEVPGRRNERFYDCCKEP------YPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPEGGKMPKWTRVVLLNWCAWFLRMKRPGEDKVRPACHNKQ 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Zebrafish
Match: chrna5 (cholinergic receptor, nicotinic, alpha 5 [Source:ZFIN;Acc:ZDB-GENE-050417-440])

HSP 1 Score: 172.555 bits (436), Expect = 2.635e-47
Identity = 125/409 (30.56%), Postives = 200/409 (48.90%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGS-YYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNV--GEKSKDVKMPKFLKRIL---NSRFLCL-----HHKTHNKFRSGSAN-----SKDNN--DNEENI---CEKLTY-----------------WRRLATLLDRVF 1284
            L  +L   Y     P+ D  T   V   + + QL D+DE  Q++T +VWM+  W D  L WDP  + G+  I +P+  I+ PD++ Y +  GNFE  +     + A +R +G +     A  KS C +D+  FP+D Q C++ F SW  D S  +I  +D    K   F    NGEWE+V+      L +         +G+ +Y  +T+   ++R P F  ++LI PC+ L +++ L F LP   GEK++L  ++L+S+ VFLL++ E IP +S  IP +G +   ++  V LS+++T   +N+     S    M  +++RI      R LC+      + T    R+G        S+D N  D E N+    E + Y                 W+ +A +LDRVF
Sbjct:   39 LFKHLFSNYQKWVRPIEDLNTTIQVKFGLAISQLVDVDEKNQLMTTNVWMKQEWTDLKLRWDPDHYLGITSIRVPSDSIWIPDIVLYDNADGNFEATV-----TKAVVRFDGTISWTPPANYKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQVDILLEDVHVDKRDYF---DNGEWEIVKATGNRGLRR---------DGTFFYPSITYSFIIRRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNGGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIVITVFAINIHHRSSSTHHSMAPWVRRIFLHHLPRLLCMRSHVDRYATSAGTRTGGLGYGKSLSQDTNQLDAEHNLQAALESIRYITRHVVKENEVREVVQDWKFVAQVLDRVF 430
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Zebrafish
Match: chrna5 (cholinergic receptor, nicotinic, alpha 5 [Source:ZFIN;Acc:ZDB-GENE-050417-440])

HSP 1 Score: 172.555 bits (436), Expect = 2.635e-47
Identity = 125/409 (30.56%), Postives = 200/409 (48.90%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGS-YYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNV--GEKSKDVKMPKFLKRIL---NSRFLCL-----HHKTHNKFRSGSAN-----SKDNN--DNEENI---CEKLTY-----------------WRRLATLLDRVF 1284
            L  +L   Y     P+ D  T   V   + + QL D+DE  Q++T +VWM+  W D  L WDP  + G+  I +P+  I+ PD++ Y +  GNFE  +     + A +R +G +     A  KS C +D+  FP+D Q C++ F SW  D S  +I  +D    K   F    NGEWE+V+      L +         +G+ +Y  +T+   ++R P F  ++LI PC+ L +++ L F LP   GEK++L  ++L+S+ VFLL++ E IP +S  IP +G +   ++  V LS+++T   +N+     S    M  +++RI      R LC+      + T    R+G        S+D N  D E N+    E + Y                 W+ +A +LDRVF
Sbjct:   39 LFKHLFSNYQKWVRPIEDLNTTIQVKFGLAISQLVDVDEKNQLMTTNVWMKQEWTDLKLRWDPDHYLGITSIRVPSDSIWIPDIVLYDNADGNFEATV-----TKAVVRFDGTISWTPPANYKSACTIDVTFFPFDLQNCSMKFGSWTYDGSQVDILLEDVHVDKRDYF---DNGEWEIVKATGNRGLRR---------DGTFFYPSITYSFIIRRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNGGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIVITVFAINIHHRSSSTHHSMAPWVRRIFLHHLPRLLCMRSHVDRYATSAGTRTGGLGYGKSLSQDTNQLDAEHNLQAALESIRYITRHVVKENEVREVVQDWKFVAQVLDRVF 430
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Zebrafish
Match: FO907089.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:101882451])

HSP 1 Score: 172.555 bits (436), Expect = 1.178e-46
Identity = 114/360 (31.67%), Postives = 191/360 (53.06%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSAN 1197
            VS+  +  + +Y  L+    + YNPL  PV ++     V     L Q+ D+DE  Q+LT ++W+++ W D  L W+  D+ G++ +  P   I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D QRC+L F SW       ++   +A D  G+     +NGEW++VE P       Y    +       Y +VTF + ++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV+ T +VL       D  KMPK+ + +L    + FL +     ++ R    N
Sbjct:   50 VSLQGEHQRRLYRDLM----KNYNPLERPVYNDSHSLTVHFSFSLMQIMDVDEKNQVLTTNIWLQLYWTDYYLRWNMSDYPGVNTVRFPDSLIWRPDILLYNSADERFDATF----HTNVLVNSSGYCQYLPPGIFKSTCYIDVRWFPFDVQRCDLKFGSWTYGGWALDLQMINA-DITGY----IANGEWDLVEVPGRRNEKFYDCCKEP------YPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVLVLQYHYHDPDGAKMPKWTRVLLLNWCAWFLRMRRPGEDRIRLACHN 390
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Xenopus
Match: ENSXETT00000021532.1 (cholinergic receptor, nicotinic alpha 7 [Source:NCBI gene;Acc:100493611])

HSP 1 Score: 177.948 bits (450), Expect = 9.429e-49
Identity = 119/380 (31.32%), Postives = 202/380 (53.16%), Query Frame = 1 
Query:   55 FGIGVFVLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKS-KDVKMPKFLKRIL---NSRFLCLHHKTHNKFR 1182
             G G F +  I  VC+ +       VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++M W D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q+CNL F SW       ++   ++  S     +  SNGEW++V  P   + + Y+   +       Y +VTF + ++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL           MPK+ + IL    + FL +     +K R
Sbjct:    3 MGRGEFTVWMIIAVCFMN-------VSLQGEYQRKLYKELM----KNYNPLERPVLNDSHPLTVYFGMSLMQIMDVDEKNQVLTTNIWLQMQWIDYYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDASF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDIQKCNLKFGSWTYGGWSLDLQMLESDIS-----EYISNGEWDLVGVPGKRSENYYECCKEP------YLDVTFTIIMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPHGGNMPKWTRIILLNWCAWFLRMKRPGEDKVR 356
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Xenopus
Match: rpap1 (RNA polymerase II associated protein 1 [Source:Xenbase;Acc:XB-GENE-976775])

HSP 1 Score: 167.933 bits (424), Expect = 9.777e-46
Identity = 114/398 (28.64%), Postives = 192/398 (48.24%), Query Frame = 1 
Query:  184 LKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGS----YYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV--KMPKFLKRIL---NSRFLCLHHKTHNKF----RSGSANSKDNNDN------------------EENICEKLTYWRRLATLLDRVF 1284
            L Q Y     PV        V   + + QL D+DE  Q++T +VW++  W D  L WDP++F G+  I +P+  I+ PD++ Y +  G FE  +     + A +R +G +     A  KS C +D+  FP+D Q C++ F SW  D S  +I  +D    K   F    NGEWE+V              +   GN +    +Y  +T+   ++R P F  ++LI PC+ L +++ L F LP   GEK++L  ++L+S+ VFLL++ E IP +S  IP +G +   ++  V LS+++T   +N+  +S      M  ++++I      + LC+       F     +G     +++ N                  E  + E +  W+ +A +LDR+F
Sbjct:    5 LSQDYQRWVRPVEHLNDTVKVKFGLAITQLVDVDEKNQLMTTNVWLKQEWVDVKLRWDPNEFAGITSIRVPSDSIWIPDIVLYDNADGRFEGSV-----TKAVVRYDGTINWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDYHVDKRDFF---DNGEWEIVN------------ATGNKGNRTDGCCFYPYITYSFIIKRLPLFYTLFLIIPCIGLSFLTILVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIVLTVFAINIHNRSSATHNAMAPWVRKIFLHKLPKLLCMRSHVDRYFTRKDETGKVRGPESSRNTLEAALDSIRYITRHVMKEHEVQEVVEDWKFVAQVLDRMF 382
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Xenopus
Match: usp16 (ubiquitin specific peptidase 16 [Source:Xenbase;Acc:XB-GENE-1007164])

HSP 1 Score: 168.703 bits (426), Expect = 1.027e-45
Identity = 101/323 (31.27%), Postives = 179/323 (55.42%), Query Frame = 1 
Query:  187 KQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKN--ASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSRF 1146
            K  YN L  P  +N     + + + L QL  ++E  Q++T +VW+   W D  LTW+P D++G+ ++ +P+ +I+ PD++ Y +  G +E  +F    + A +++NG V     A+ KS C+++++ FP+D Q C L F SW      ++ T+ D   +KG +  +    +GEW+++E P   T+               Y +VT+   ++RKP F  + LI PC+L+  ++ L F LP + G+K+ L +++LL++ VFLLL+S+ +P TS  +P +G +   ++ LV  S++ +  VLNV  +S     MP ++K     R 
Sbjct:   20 KDKYNKLIRPAYNNSQLVSIQLQLSLAQLISVNEREQIMTTNVWLNQEWVDYRLTWNPADYDGIKKLRIPSQQIWLPDIVLYNNADGTYEVSLF----TNAIVQNNGSVAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWT-----YDYTEIDLVLNKGWATMDDFTPSGEWDIIELPGRRTICPL---------DPTYVDVTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGQKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKNCFLDRL 324
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Xenopus
Match: usp16 (ubiquitin specific peptidase 16 [Source:Xenbase;Acc:XB-GENE-1007164])

HSP 1 Score: 169.088 bits (427), Expect = 1.210e-45
Identity = 102/323 (31.58%), Postives = 178/323 (55.11%), Query Frame = 1 
Query:  187 KQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKN--ASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSRF 1146
            K  YN L  P  +N     + + + L QL  ++E  Q++T +VW+   W D  LTW+P D++G+ ++ +P+ +I+ PD++ Y +  G +E  +F    + A +++NG V     A+ KS C+++++ FP+D Q C L F SW  D      T+ D   +KG +  +    +GEW+++E P   T+               Y +VT+   ++RKP F  + LI PC+L+  ++ L F LP + G+K+ L +++LL++ VFLLL+S+ +P TS  +P +G +   ++ LV  S++ +  VLNV  +S     MP ++K     R 
Sbjct:   38 KDKYNKLIRPAYNNSQLVSIQLQLSLAQLISVNEREQIMTTNVWLNQEWVDYRLTWNPADYDGIKKLRIPSQQIWLPDIVLYNNADGTYEVSLF----TNAIVQNNGSVAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDY-----TEIDLVLNKGWATMDDFTPSGEWDIIELPGRRTICPL---------DPTYVDVTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGQKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKNCFLDRL 342
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Xenopus
Match: usp16 (ubiquitin specific peptidase 16 [Source:Xenbase;Acc:XB-GENE-1007164])

HSP 1 Score: 168.703 bits (426), Expect = 1.744e-45
Identity = 102/323 (31.58%), Postives = 178/323 (55.11%), Query Frame = 1 
Query:  187 KQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKN--ASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSRF 1146
            K  YN L  P  +N     + + + L QL  ++E  Q++T +VW+   W D  LTW+P D++G+ ++ +P+ +I+ PD++ Y +  G +E  +F    + A +++NG V     A+ KS C+++++ FP+D Q C L F SW  D      T+ D   +KG +  +    +GEW+++E P   T+               Y +VT+   ++RKP F  + LI PC+L+  ++ L F LP + G+K+ L +++LL++ VFLLL+S+ +P TS  +P +G +   ++ LV  S++ +  VLNV  +S     MP ++K     R 
Sbjct:   50 KDKYNKLIRPAYNNSQLVSIQLQLSLAQLISVNEREQIMTTNVWLNQEWVDYRLTWNPADYDGIKKLRIPSQQIWLPDIVLYNNADGTYEVSLF----TNAIVQNNGSVAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDY-----TEIDLVLNKGWATMDDFTPSGEWDIIELPGRRTICPL---------DPTYVDVTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGQKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKNCFLDRL 354
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Mouse
Match: Chrna7 (cholinergic receptor, nicotinic, alpha polypeptide 7 [Source:MGI Symbol;Acc:MGI:99779])

HSP 1 Score: 176.022 bits (445), Expect = 3.803e-48
Identity = 113/355 (31.83%), Postives = 194/355 (54.65%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFR 1182
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + ++G  Q     + KS C +D+R FP+D Q+C L F SW+      ++  ++A  S         NGEW+++  P       Y+   +       Y +VT+ +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R
Sbjct:   19 VSLQGEFQRRLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDLQMQEADIS-----SYIPNGEWDLMGIPGKRNEKFYECCKEP------YPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVR 354
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Mouse
Match: Chrnb3 (cholinergic receptor, nicotinic, beta polypeptide 3 [Source:MGI Symbol;Acc:MGI:106212])

HSP 1 Score: 171.014 bits (432), Expect = 1.059e-46
Identity = 107/333 (32.13%), Postives = 184/333 (55.26%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV--KMPKFLKRILNS---RFLCL 1155
            L+ +L QGY     PV ++     V+  + + QL D+DE  Q++T +VW++  W D  L W+P D+ G++ I +P+  ++ PD++ +++  G FE  +     + A ++S+G V     A  KS C +D+  FP+D Q C++ F SW  D ++ ++   +    +   F    NGEWE++        +K   G+   G  S Y  VT+   L+R P F  ++LI PC+ L +++ L F LP + GEK++LS ++L+S+ VFLL++ E IP +S  IP +G +    +  V LS+++T  V+NV  +S      M  ++KR+      R+LC+
Sbjct:   38 LLRHLFQGYQKCVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEDYGGINSIKVPSESLWLPDIVLFENADGRFEGSL----MTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDKQNCSMKFGSWTYDGTMVDLILINENVDRKDFF---DNGEWEILN-------AKGMKGNRREGFYS-YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLEKLPRWLCM 355
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Mouse
Match: Chrnb3 (cholinergic receptor, nicotinic, beta polypeptide 3 [Source:MGI Symbol;Acc:MGI:106212])

HSP 1 Score: 171.014 bits (432), Expect = 1.237e-46
Identity = 107/333 (32.13%), Postives = 184/333 (55.26%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV--KMPKFLKRILNS---RFLCL 1155
            L+ +L QGY     PV ++     V+  + + QL D+DE  Q++T +VW++  W D  L W+P D+ G++ I +P+  ++ PD++ +++  G FE  +     + A ++S+G V     A  KS C +D+  FP+D Q C++ F SW  D ++ ++   +    +   F    NGEWE++        +K   G+   G  S Y  VT+   L+R P F  ++LI PC+ L +++ L F LP + GEK++LS ++L+S+ VFLL++ E IP +S  IP +G +    +  V LS+++T  V+NV  +S      M  ++KR+      R+LC+
Sbjct:   38 LLRHLFQGYQKCVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEDYGGINSIKVPSESLWLPDIVLFENADGRFEGSL----MTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDKQNCSMKFGSWTYDGTMVDLILINENVDRKDFF---DNGEWEILN-------AKGMKGNRREGFYS-YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLEKLPRWLCM 355
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Mouse
Match: Chrna5 (cholinergic receptor, nicotinic, alpha polypeptide 5 [Source:MGI Symbol;Acc:MGI:87889])

HSP 1 Score: 163.696 bits (413), Expect = 2.640e-44
Identity = 107/393 (27.23%), Postives = 187/393 (47.58%), Query Frame = 1 
Query:  184 LKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV--KMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSKDNND---------------------NEENICEKLTYWRRLATLLDRVF 1284
            L + Y     PV     K  +   + + QL D+DE  Q++T +VW++  W D  L W+P D+ G+  I +P+  ++ PD++ + +  G FE        +   +R NG V     A  KS C +D+  FP+D Q C++ F SW  D S  +I  +D    +   F    NGEWE+        +S      + + +  +Y  +T+   ++R P F  ++LI PC+ L +++ + F LP   GEK++L  ++L+S+ VFLL++ E IP +S  IP +G +   ++  V LS+++T   +N+  +S      M  ++++I      + LC+       F       KD                         E ++ E +  W+ +A +LDR+F
Sbjct:   25 LFEDYEKWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKIIRVPSDSLWIPDIVLFDNADGRFEGA-----STKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDRTDFF---DNGEWEI--------MSAMGSKGNRTDSCCWYPCITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSHADRYFTQREEAEKDGGPKSRNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMF 401
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Mouse
Match: Chrna9 (cholinergic receptor, nicotinic, alpha polypeptide 9 [Source:MGI Symbol;Acc:MGI:1202403])

HSP 1 Score: 164.466 bits (415), Expect = 3.882e-44
Identity = 110/327 (33.64%), Postives = 182/327 (55.66%), Query Frame = 1 
Query:  184 LKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNI-TKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNV---GEKSKDVK------MPKFLKRIL 1134
            L + Y+    PV D     +V + + L Q+ D+DE  Q+LT  +W+  +W D  LTWD   ++GLD I +P+  ++ PD++ Y        E +     +   +R +G++   + A+ KS C VD+  FP+D+Q+CNLTF SW  + +  +I    D+GD          + EWEV   PA   +  Y   S+       Y +VTF L L+R+ +F  V L+ PCVL+ +++ L+F LP  SGEKV+L VTILL++ VF L+V+E +P  S+ +P +G ++  ++ L+  S  +T +V+N+   G +++ V       + K++ RIL
Sbjct:   38 LFEDYSNALRPVEDTDAVLNVTLQVTLSQIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPV----NTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNGNQVDIFNALDSGDLSDF----IEDVEWEVQGMPAVKNVISYGCCSEP------YPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMP-ASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRIL 349
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. UniProt/SwissProt
Match: sp|P22770|ACHA7_CHICK (Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus gallus OX=9031 GN=CHRNA7 PE=1 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 1.050e-49
Identity = 118/361 (32.69%), Postives = 198/361 (54.85%), Query Frame = 1 
Query:  133 SISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            S+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++M W D  L W+  ++ G+  +  P G I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q+CNL F SW       ++  ++A D  G+     SNGEW++V  P   T S Y+   +       Y ++TF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   20 SLQGEFQRKLYKELL----KNYNPLERPVANDSQPLTVYFTLSLMQIMDVDEKNQVLTTNIWLQMYWTDHYLQWNVSEYPGVKNVRFPDGLIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQKCNLKFGSWTYGGWSLDLQMQEA-DISGY----ISNGEWDLVGIPGKRTESFYECCKEP------YPDITFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. UniProt/SwissProt
Match: sp|P36544|ACHA7_HUMAN (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens OX=9606 GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 181.03 bits (458), Expect = 3.277e-49
Identity = 117/362 (32.32%), Postives = 198/362 (54.70%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q C L F SW+      ++  ++A D  G+      NGEW++V  P   +   Y+   +       Y +VTF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   19 VSLQGEFQRKLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA-DISGY----IPNGEWDLVGIPGKRSERFYECCKEP------YPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 361
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. UniProt/SwissProt
Match: sp|Q866A2|ACHA7_MACMU (Neuronal acetylcholine receptor subunit alpha-7 OS=Macaca mulatta OX=9544 GN=CHRNA7 PE=2 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 1.839e-48
Identity = 116/362 (32.04%), Postives = 198/362 (54.70%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D Q C L F SW+      ++  ++A D  G+      +GEW++V  P   +   Y+   +       Y +VTF +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R    + +
Sbjct:   19 VSLQGEFQRKLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA-DISGY----IPSGEWDLVGIPGKRSEKFYECCKEP------YPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ 361
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BLAST of Acetylcholine receptor subunit alpha-like vs. UniProt/SwissProt
Match: sp|P49582|ACHA7_MOUSE (Neuronal acetylcholine receptor subunit alpha-7 OS=Mus musculus OX=10090 GN=Chrna7 PE=2 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 2.661e-47
Identity = 113/355 (31.83%), Postives = 194/355 (54.65%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFR 1182
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + ++G  Q     + KS C +D+R FP+D Q+C L F SW+      ++  ++A  S         NGEW+++  P       Y+   +       Y +VT+ +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R
Sbjct:   19 VSLQGEFQRRLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDLQMQEADIS-----SYIPNGEWDLMGIPGKRNEKFYECCKEP------YPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVR 354
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. UniProt/SwissProt
Match: sp|Q05941|ACHA7_RAT (Neuronal acetylcholine receptor subunit alpha-7 OS=Rattus norvegicus OX=10116 GN=Chrna7 PE=1 SV=2)

HSP 1 Score: 175.637 bits (444), Expect = 2.827e-47
Identity = 113/355 (31.83%), Postives = 194/355 (54.65%), Query Frame = 1 
Query:  130 VSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFR 1182
            VS+  +  + +Y  L+    + YNPL  PV ++     V+  + L Q+ D+DE  Q+LT ++W++MSW D  L W+  ++ G+  +  P G+I+ PD++ Y S    F+        +   + ++G  Q     + KS C +D+R FP+D Q+C L F SW+      ++  ++A  S         NGEW+++  P       Y+   +       Y +VT+ +T++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV++T IVL       D  KMPK+ + IL    + FL +     +K R
Sbjct:   19 VSLQGEFQRRLYKELV----KNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATF----HTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDLQMQEADIS-----SYIPNGEWDLMGIPGKRNEKFYECCKEP------YPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVR 354
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. TrEMBL
Match: A0A1I8JJQ2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 354.369 bits (908), Expect = 1.261e-113
Identity = 192/403 (47.64%), Postives = 264/403 (65.51%), Query Frame = 1 
Query:  139 SNKTHKSIYLPLIDYLKQG----YNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKK--DAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSY-YAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILN-SRFLCLH-------------HKTHNKFRSGSANSKDNNDNEENICEKLTYWRRLATLLDRVF 1284
            ++   K+IY  L+ +L +     Y P A+P+C+   K HV  D+ L QLFDLDEPTQMLT+DVW+E  W DC L WDP  F G+D   + A EI+ PDL++++SLHGNFEEGMF++ ++ ARI S+G VQLG QA+ K FCRVDI  FPYD+Q+CN+TF+SW +DAS F +TKK  D   S  H+F++ASNGEW+V  FP++NT+S  ++G DESG  S  Y EV FQL L+RK  F + Y++FPC+LL W++   F+LP ESGEK+    TILLS+ VFLLLV++NIPR+ D IPT+G++FC++I LV L+ +   I  N+  K +D  MP+ LK +L+ SRF+ L                      S  A  K N  ++ +  +    WR L  +LDR+F
Sbjct:   19 ASGPKKTIYDGLLRHLFENDTLPYRPGAMPICEPGGKLHVNQDMLLLQLFDLDEPTQMLTVDVWVESIWKDCRLNWDPAKFGGIDNFAIKASEIWFPDLLFFESLHGNFEEGMFIYGEATARIFSDGSVQLGTQAVFKIFCRVDISSFPYDSQQCNITFSSWTKDASTFVLTKKPSDESSSDDHAFQSASNGEWQVEGFPSFNTISSRQVGVDESGGRSRDYTEVVFQLRLKRKYLFYQAYMLFPCILLTWLTLFVFLLPAESGEKMGYVTTILLSLFVFLLLVADNIPRSGDSIPTVGVYFCLAIALVSLANVKAVISYNISLKGRDFCMPRNLKWLLSRSRFVGLRLGRGAVPTEESPAPDEGGGAASSEAKEKLNGTSDGHSKQDENQWRYLGIMLDRIF 421
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. TrEMBL
Match: A0A1I8J004 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 354.369 bits (908), Expect = 1.302e-113
Identity = 192/403 (47.64%), Postives = 264/403 (65.51%), Query Frame = 1 
Query:  139 SNKTHKSIYLPLIDYLKQG----YNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKK--DAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSY-YAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILN-SRFLCLH-------------HKTHNKFRSGSANSKDNNDNEENICEKLTYWRRLATLLDRVF 1284
            ++   K+IY  L+ +L +     Y P A+P+C+   K HV  D+ L QLFDLDEPTQMLT+DVW+E  W DC L WDP  F G+D   + A EI+ PDL++++SLHGNFEEGMF++ ++ ARI S+G VQLG QA+ K FCRVDI  FPYD+Q+CN+TF+SW +DAS F +TKK  D   S  H+F++ASNGEW+V  FP++NT+S  ++G DESG  S  Y EV FQL L+RK  F + Y++FPC+LL W++   F+LP ESGEK+    TILLS+ VFLLLV++NIPR+ D IPT+G++FC++I LV L+ +   I  N+  K +D  MP+ LK +L+ SRF+ L                      S  A  K N  ++ +  +    WR L  +LDR+F
Sbjct:   20 ASGPKKTIYDGLLRHLFENDTLPYRPGAMPICEPGGKLHVNQDMLLLQLFDLDEPTQMLTVDVWVESIWKDCRLNWDPAKFGGIDNFAIKASEIWFPDLLFFESLHGNFEEGMFIYGEATARIFSDGSVQLGTQAVFKIFCRVDISSFPYDSQQCNITFSSWTKDASTFVLTKKPSDESSSDDHAFQSASNGEWQVEGFPSFNTISSRQVGVDESGGRSRDYTEVVFQLRLKRKYLFYQAYMLFPCILLTWLTLFVFLLPAESGEKMGYVTTILLSLFVFLLLVADNIPRSGDSIPTVGVYFCLAIALVSLANVKAVISYNISLKGRDFCMPRNLKWLLSRSRFVGLRLGRGAVPTEESPAPDEGGGAASSEAKEKLNGTSDGHSKQDENQWRYLGIMLDRIF 422
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. TrEMBL
Match: A0A267FL15 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013616g1 PE=3 SV=1)

HSP 1 Score: 348.591 bits (893), Expect = 7.360e-111
Identity = 177/355 (49.86%), Postives = 244/355 (68.73%), Query Frame = 1 
Query:  154 KSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILNS-----RFLCLHHKTHNKFRSGSANSK 1203
            K+IY  L+  L  GYN  A+P+C    +  V  D+ LYQLFDLDEPTQML++DVW+E +W DC L WDP  FN + +  + + E+++PDLI+Y+SLHGNFEEGMF++ +S AR+RS+G V+LGAQALLKSFCR+DI  FPYD+QRCN+TF+SW +D S F +T+K AGD+  H+F++ASNGEWEV  FPA+  L+  ++G DES   + Y+EV FQL L+RK  F + Y++FPC+LL W++A +F LP E GE++  S TILLS++VFLLL+++NIPR+ D +P LG++FC+++ LV L  LM     N+  K  D   P +L            F   HH    K  S   N +
Sbjct:   25 KTIYDDLLTSLFDGYNSNAMPICKQGDRLEVGQDMLLYQLFDLDEPTQMLSVDVWIESTWRDCRLMWDPAGFNNVTEFAIKSEELWYPDLIFYESLHGNFEEGMFIYGESTARVRSDGWVKLGAQALLKSFCRIDISRFPYDSQRCNITFSSWTKDTSNFLLTRK-AGDANDHAFESASNGEWEVTGFPAFTQLTPRQIGVDESAEPAIYSEVVFQLRLRRKYLFHQAYMLFPCMLLAWLAAFSFFLPTECGERIAYSTTILLSLVVFLLLIADNIPRSGDAVPVLGVYFCLTVCLVGLCTLMVIAAYNISLKPNDFCPPAWLTACCYRLGPLVGFRATHHNGRVKLLSFRMNPR 378
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. TrEMBL
Match: A0A267FEH2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig025449g1 PE=3 SV=1)

HSP 1 Score: 340.502 bits (872), Expect = 1.431e-107
Identity = 180/389 (46.27%), Postives = 250/389 (64.27%), Query Frame = 1 
Query:   61 IGVFVLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKK--DAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILNS-----RFLCLHHKTHNKFRSGSANSKD 1206
            +G  +L      C+   +  +AP     KT   IY  L+ +L   Y P A+P+C    K  V  D+ LYQLFDLDEPTQML++DVW+E +W DC L WDP  FN + +  + + +I++PDLI+Y+SLHGNFEEGMF++ +S AR+R +G V+LGAQAL K+FCRV+IR FPYD+QRCN+TF+SW +DA  F + +K  + GD K H+F  ASNGEWEV  FP+YN ++   +G  E+     Y EV FQL L+RK  F + Y++FPC+LL W++A  F LP E GE++    TILLS++VFLLLV+ENIPR+ D +P LG++FC+++ LV ++ LM     NV  K  D   P++L+R          FL  HH    K      N ++
Sbjct:    4 LGAILLTMGAAFCWLPSSVSQAPPPPPKKT---IYDNLLTHLFDKYAPSAMPICKVGDKLEVSQDMLLYQLFDLDEPTQMLSVDVWVESTWQDCRLVWDPASFNNVTEFAIKSEQIWYPDLIFYESLHGNFEEGMFIYGESTARVRHDGWVKLGAQALFKAFCRVNIRQFPYDSQRCNITFSSWTKDARTFRLKRKSGETGDKKDHAFAEASNGEWEVTGFPSYNRMTARNIGVLENETAE-YTEVVFQLRLRRKYLFHQTYMLFPCMLLTWLAAFAFFLPTECGERIAYITTILLSLVVFLLLVAENIPRSGDAVPILGVYFCLAVCLVSVANLMVIASYNVSLKPNDFCPPEWLRRCCFRLGPLVGFLPTHHNGRAKLLEFRMNPRN 388
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. TrEMBL
Match: A0A267DIL7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026767g3 PE=3 SV=1)

HSP 1 Score: 338.961 bits (868), Expect = 2.118e-107
Identity = 187/405 (46.17%), Postives = 260/405 (64.20%), Query Frame = 1 
Query:  157 SIYLPLIDYLKQG----YNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDA--GDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDE-SGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILNS-RFLCLHHKTHN-----------KFRSGSANSKDNNDN----------EENICEKLTYWRRLATLLDRVF 1284
            +IY  L+ YL +     Y   A+P+C+   K  +  D+ L QLFDLDEPTQMLT+DVW+E +W DC LTWDP  FN +D   + A EI++PDLI+Y+SLHGNFEEGMF++ +S ARI S+G +QLGAQA+ KSFCR++I  FPYD QRCN+TF+SW +D S F + KK+   G  + H+F +ASNGEW V  FP+++ ++  K+G DE SG    Y+EV FQL L+RK  F +VY++FPC+LL W++   F++P E GEK+    TILLS++VFLL+VS+NIPR+ D +P LG++FC++I LV L+ + T I  N+  K KD  MP    +IL S +++ L    HN           K R    N    +++          E +  +    WR L  +LDRVF
Sbjct:   35 TIYDGLLAYLFENETTPYKANAMPICELGKKLKIQQDMLLIQLFDLDEPTQMLTVDVWVESTWKDCRLTWDPKRFNNIDNFVIKAEEIWYPDLIFYESLHGNFEEGMFIYGESKARIFSDGSIQLGAQAVFKSFCRINIAQFPYDRQRCNITFSSWTKDTSNFLLVKKEEAPGKKEDHAFVSASNGEWMVEGFPSFDRVADRKVGLDEASGRSRQYSEVAFQLRLKRKYMFQQVYMLFPCMLLTWLTLFVFIMPTECGEKIAYVTTILLSLMVFLLMVSDNIPRSGDAVPVLGIYFCIAIALVSLANIKTIISYNISLKGKDFCMPACFIKILESGKYVGLPLTHHNEAAVKVISFAMKPRQAGQNPVTRHEDSEVPLSTTNPESHFGQDENKWRFLGIILDRVF 439
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Cavefish
Match: ENSAMXT00000053066.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:103033738])

HSP 1 Score: 176.407 bits (446), Expect = 8.868e-49
Identity = 112/342 (32.75%), Postives = 183/342 (53.51%), Query Frame = 1 
Query:  190 QGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            + YNPL  PV ++     V     L Q+ D+DE  Q+LT ++W+++ W D  L W+  D+ G+  +  P  +I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D QRC+L F SW       ++   DA D  G+     +NGEW++VE P       Y    +       Y +VTF + ++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV+ T +VL       D  KMPK+ + +L    + FL +      + RS   N +
Sbjct:    2 RNYNPLERPVFNDSQSLTVHFSFSLMQIMDVDEKNQVLTTNIWLQLYWVDYYLQWNVTDYPGVANVRFPDNQIWRPDILLYNSADERFDATF----HTNVLVNSSGYCQYLPPGIFKSTCYIDVRWFPFDVQRCDLKFGSWTYGGWSLDLQMMDA-DITGY----IANGEWDLVEVPGRRNEKFYDCCKEP------YPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVLVLQYHHHDPDGGKMPKWTRVLLLNWCAWFLRMRRPGEERVRSACHNKQ 328
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Cavefish
Match: ENSAMXT00000055784.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:103033738])

HSP 1 Score: 176.407 bits (446), Expect = 1.356e-48
Identity = 112/342 (32.75%), Postives = 183/342 (53.51%), Query Frame = 1 
Query:  190 QGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNKFRSGSANSK 1203
            + YNPL  PV ++     V     L Q+ D+DE  Q+LT ++W+++ W D  L W+  D+ G+  +  P  +I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D QRC+L F SW       ++   DA D  G+     +NGEW++VE P       Y    +       Y +VTF + ++R+  +  + L+ PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV+ T +VL       D  KMPK+ + +L    + FL +      + RS   N +
Sbjct:    2 RNYNPLERPVFNDSQSLTVHFSFSLMQIMDVDEKNQVLTTNIWLQLYWVDYYLQWNVTDYPGVANVRFPDNQIWRPDILLYNSADERFDATF----HTNVLVNSSGYCQYLPPGIFKSTCYIDVRWFPFDVQRCDLKFGSWTYGGWSLDLQMMDA-DITGY----IANGEWDLVEVPGRRNEKFYDCCKEP------YPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVLVLQYHHHDPDGGKMPKWTRVLLLNWCAWFLRMRRPGEERVRSACHNKQ 328
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Cavefish
Match: chrnb3a (cholinergic receptor, nicotinic, beta polypeptide 3a [Source:ZFIN;Acc:ZDB-GENE-040108-1])

HSP 1 Score: 169.088 bits (427), Expect = 3.577e-46
Identity = 109/338 (32.25%), Postives = 179/338 (52.96%), Query Frame = 1 
Query:  190 QGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPK-------FLKRILNSRFLCLHHKTHNKFR 1182
            +GY     PV        V   + + QL D+DE  Q++T +VW+   W D  L WDP D+ G+  I +P+  I+ PD++ Y++  G FE  +     + A ++ +G +     A  KS C +D+  FP+D Q C++ F SW  D ++ ++   D    +   F    NGEWE+++       +  + GS   G  S Y  VT+   L+R P F  ++LI PC+ L +++ L F LP + GEK++LS ++L+S+ VFLL++ E IP +S  IP +G +    +  V  S+++T  V+NV  +S     P        FL+R+   R LC+H  T +++R
Sbjct:   27 RGYQKWVRPVFHANDTIAVRFGLKISQLVDVDEKNQLMTTNVWLWQEWTDYKLRWDPEDYGGITSIRVPSENIWLPDIVLYENADGRFEGSL----MTKAIVKYDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLALVDQHVDRKDFF---DNGEWEILD-------ATGRRGSRRDGIYS-YPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRL--PRLLCMHGHT-DRYR 346
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Cavefish
Match: chrnb3a (cholinergic receptor, nicotinic, beta polypeptide 3a [Source:ZFIN;Acc:ZDB-GENE-040108-1])

HSP 1 Score: 168.318 bits (425), Expect = 7.540e-46
Identity = 109/338 (32.25%), Postives = 179/338 (52.96%), Query Frame = 1 
Query:  190 QGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPK-------FLKRILNSRFLCLHHKTHNKFR 1182
            +GY     PV        V   + + QL D+DE  Q++T +VW+   W D  L WDP D+ G+  I +P+  I+ PD++ Y++  G FE  +     + A ++ +G +     A  KS C +D+  FP+D Q C++ F SW  D ++ ++   D    +   F    NGEWE+++       +  + GS   G  S Y  VT+   L+R P F  ++LI PC+ L +++ L F LP + GEK++LS ++L+S+ VFLL++ E IP +S  IP +G +    +  V  S+++T  V+NV  +S     P        FL+R+   R LC+H  T +++R
Sbjct:   41 RGYQKWVRPVFHANDTIAVRFGLKISQLVDVDEKNQLMTTNVWLWQEWTDYKLRWDPEDYGGITSIRVPSENIWLPDIVLYENADGRFEGSL----MTKAIVKYDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLALVDQHVDRKDFF---DNGEWEILD-------ATGRRGSRRDGIYS-YPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRL--PRLLCMHGHT-DRYR 360
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Cavefish
Match: chrnb5a (neuronal acetylcholine receptor subunit beta-2 [Source:NCBI gene;Acc:103027465])

HSP 1 Score: 166.007 bits (419), Expect = 6.048e-45
Identity = 109/360 (30.28%), Postives = 190/360 (52.78%), Query Frame = 1 
Query:  148 THKSIYLPLIDYL--KQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSR---FLCLHHKTHNKFRSGSANSKDN 1209
            TH      L+++L   + YN L  P  +   +  + + + L QL  ++E  Q++T +VW+   W D  L WDP +++G+ ++ +P+  I+ PD++ Y +  G +E   +    S A + + G +     A+ +S C +++R FP+D Q C L F SW  D +  ++       S+        +GEW++V  P            +E  N   Y +VT+   ++RKP F  + LI PCVL+  ++ L F LP + GEKV L +++LL++ VFLLL+S+ +P TS  +P +G +   ++ LV  S++ +  VLNV  +S    +MP+++KR+   R   FL +        R GS+N ++ 
Sbjct:    3 THTYAEERLVEFLLGPERYNKLIRPAVNKSQQVTIGIKVSLAQLISVNEREQIMTTNVWLTQEWNDYRLVWDPDEYDGIKKLRIPSHHIWLPDIVLYNNADGVYEVSFY----SNAIVANTGDIFWLPPAIYRSACAIEVRNFPFDQQNCTLKFRSWTYDRTELDLVLTSDFASRDDY---TPSGEWDIVSLPGRK---------NEDPNDLTYMDVTYDFVIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKVTLCISVLLALTVFLLLISKIVPPTSLAVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHRMPEWVKRVFLRRLPVFLLMR-------RPGSSNVREK 339
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Sea Lamprey
Match: chrna3 (cholinergic receptor, nicotinic, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-070822-1])

HSP 1 Score: 163.696 bits (413), Expect = 1.372e-44
Identity = 107/350 (30.57%), Postives = 188/350 (53.71%), Query Frame = 1 
Query:  184 LKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFE-EGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSRFLCLHHKTHNKFRSGSANSKDNNDNEEN 1227
            L   YNP   PV +      V  ++ + QL  LDE  Q++  ++W++ +W D    W+P  F G++ I +P+ +I+ PD++ Y +  G+F+ EG     ++ A ++ +G V     A+ KS C++D+  FP+D Q C + F SW  D +  ++       +K +      +GEW +++ P Y    KY            Y ++T+ + ++R P F  + LI PC+L+ +++ L F LP + GEKV LS+++LLS+ VFLL+++E IP TS  IP +G +   ++  V LS+++T  VLNV  ++ +   MP +++R+       +      K   G+A S D   +E +
Sbjct:   15 LFTSYNPYIRPVFNVSDPVIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVLYNNADGDFQVEG-----KTKALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLV---LVGTKINLKDFWESGEWVIIDVPGYKHDIKYNCCE------QIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHYRTPEAHTMPNWVRRVFLDTLPKIMLLQPPKGSVGTAASPDAVVSEAD 350
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Sea Lamprey
Match: chrnb3b (cholinergic receptor, nicotinic, beta 3b (neuronal) [Source:ZFIN;Acc:ZDB-GENE-030102-4])

HSP 1 Score: 162.925 bits (411), Expect = 1.541e-44
Identity = 95/314 (30.25%), Postives = 167/314 (53.18%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMP 1113
            L+  + + Y     PV        V   + + QL D+DE  Q++T +VW++  W D  L W+P D+ G++ I +PA  I+ PD++ Y +  G FE  +     + A ++ +G ++    A+ KS C +D+  FP+D Q C++ F SW  D ++ ++   ++   +G  F    NGEWE +        +    G    G+  +Y  +T+   ++R P F  ++LI PC+ L +++   F LP + GEK++L  ++L+S+ VFLL++ E IP +S  IP +G +    +  V LS+++T  V+NV  +S     P
Sbjct:   38 LLKRMLKDYQKWVRPVDKLSDTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDIVLYDNADGRFEGSIV----TKAVVKHDGRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDLIMVNSDVDRGEYF---DNGEWEFLN-------ATGNKGVRLDGH-RFYPYITYSFVIRRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITVFVINVHHRSSSTHHP 336
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Sea Lamprey
Match: chrna2a (cholinergic receptor, nicotinic, alpha 2a (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-2])

HSP 1 Score: 145.206 bits (365), Expect = 1.342e-37
Identity = 94/294 (31.97%), Postives = 156/294 (53.06%), Query Frame = 1 
Query:  268 QLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNA-SNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSR 1143
             L D DE  QM+T +VW++  W D  L WDP ++  +  I +P+  I+ PD++ Y +  G+F     +   + A +   G V+    A+ KS C +D+  FP+D Q C + F SW  D +  ++       ++    K+   +GEW +V         KY            Y ++T+   ++R P F  + LI PC+L+  ++ L F LP + GEK+ L +++LLS+ VFLLL++E IP TS  IP +G +   ++  V LS+++T  VLNV  +S     MP++++R+   R
Sbjct:    9 HLCDCDEKNQMMTTNVWLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYNNADGDFA----VTHMTKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSM----ARDVDLKDYWESGEWAIVHAVGTYNTKKYDCCP------QVYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPATHAMPRWVRRVFLDR 288
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Sea Lamprey
Match: htr3a (5-hydroxytryptamine (serotonin) receptor 3A [Source:ZFIN;Acc:ZDB-GENE-071012-5])

HSP 1 Score: 134.42 bits (337), Expect = 2.327e-34
Identity = 109/371 (29.38%), Postives = 188/371 (50.67%), Query Frame = 1 
Query:  139 SNKTHKSIYLP-LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLH-GNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITK-KDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVK--MPKFLKRILNSR---FLCLHHKTHNKFRS----GSANSKDNND 1215
            S   HK   L  L   L  GY+    PV + +    V +D+ LY + ++DE  Q+LT  +W    W D  L WDP  ++G++QI++P   I+ PD++  + +  G   +  +++      +  NG V       + S C +DI  FP+D Q C LTF SW   ++  N+T  +   + K       + GEWE++  P  N L     G +       ++E+   + ++R+P F  V LI P   L+ + A  F LP +SGE+V+  +T+LL   VFL++V + +P T  G P + ++F + + L+ +S++ T  ++ +  K +DV+  +P +LK+ L SR    LC     + +  +    G+ N+ DN +
Sbjct:   26 STNAHKKTPLRNLSSRLSSGYDKGVRPVKNWRQPIIVAIDVMLYAILNVDEKNQVLTAYIWYRQRWTDEFLQWDPVQYDGIEQISIPTNNIWVPDIMISEFVDVGKSPDIGYVY------LSYNGTVMNYKPLQVVSACSLDIYSFPFDVQNCTLTFTSWLHTSNDINLTLWRTTEEIKEDKSIFLNFGEWELISVP--NELLHPLYGENR------FSELKIYVVIRRRPLFYVVNLIMPSAFLMVMDA-GFYLPPDSGERVSFKITLLLGYSVFLIVVQDTLPATPIGTPLIAVYFVVCMALLVISLMETIFIVRLVHK-QDVQSHVPPWLKKWLLSRGSVILCRKQIPYPRSVTFPNDGAQNAADNGE 380
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008550.1 (pep scaffold:Pmarinus_7.0:GL476601:34:38373:1 gene:ENSPMAG00000007717.1 transcript:ENSPMAT00000008550.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.568 bits (327), Expect = 2.495e-33
Identity = 87/255 (34.12%), Postives = 145/255 (56.86%), Query Frame = 1 
Query:  373 GLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL 1134
            G+  +     +I+ PD++ Y S    F+        +   +   G  Q     +LKS C +D+R FP+D Q+C+L F SW  D  + ++   +A D+ G+     +NGEW++VE P       Y    +       Y +VT+ LT++R+  +  + L+ PCVL+  +S L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +G +F  ++ +V  SV++T IVL     + D  KMP++++ IL
Sbjct:    5 GVKNLRFQPHQIWTPDILLYNSADERFDATF----HTNVLVNYTGNCQHLPPGMLKSTCYIDVRWFPFDVQKCDLKFGSWTHDGWLIDLQMLEA-DTSGY----IANGEWDLVEIPGKRNELYYDCCQEP------YPDVTYTLTIRRRTLYYGLNLLVPCVLISALSLLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQYFASTMIIVAFSVVVTVIVLQYHHHNPDGKKMPQWVRVIL 244
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Nematostella
Match: EDO37424 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFW9])

HSP 1 Score: 160.614 bits (405), Expect = 5.171e-45
Identity = 96/307 (31.27%), Postives = 174/307 (56.68%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNIT--KKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVG 1086
            L+  + + Y+    PV ++K   +V  DI    + D++E  Q+LTI +W+  +W + + TWDP ++ G+ ++ L A +++ PD+I YQ++  +F +G      +  RI S+GM       ++ + C +++  FP+DTQ+C LTF SW  D +  N+   +K A  +K        NGEW++        +  Y     +   G  Y EV F + ++RK  F  V L+ P +L+  ++  +F +P+E GE+++  +T+LLS+ VF+LLV+++IP TS+ +P +G+F+  S+  V L+++ T I L + 
Sbjct:    3 LVRDILKNYDKRVRPVRNSKDAVNVTFDITFNNIIDVEEKRQILTISLWLRQTWLNQLTTWDPEEYGGVKEVVLQARDVWQPDIILYQNIIQDF-DGRLDHTNTRVRITSSGMTYWSMPFVVVTLCTINVSDFPFDTQQCKLTFGSWQHDGNEINLINDRKQALLAKTR----VKNGEWQIQNITVDRRVVYY-----QCCPGQPYPEVGFIVNMKRKSLFYFVNLLLPNILICLLAFFSFFIPVECGERISFVITVLLSMTVFMLLVADSIPPTSEAVPLIGIFYSASMIEVFLALIATGISLKIN 299
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Nematostella
Match: EDO46927 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNI2])

HSP 1 Score: 164.466 bits (415), Expect = 1.250e-44
Identity = 106/321 (33.02%), Postives = 170/321 (52.96%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRIL 1134
            L++ L + YN  A PV +      V  D+   QL +L+   Q+L   VW    W +  LTWDP  + GL  I +    I+ PD++ Y ++ G  E G      + A I  NG  +  A   + S C +DI  FP+D Q C + F SW+      N+T K  GDS   S K   +GEW+++   A   + KY    D       + ++TF + ++RK  F    LI PC++L  ++  +F LP+ESGE++ L +TI L + VF+L+ +EN+PRTS+ IP +G +    + +V  S+++T  +L V  K  ++KM  + K+++
Sbjct:   30 LLNDLFKDYNKEARPVLNKSEAIEVQFDMAYAQLINLNSKDQILQSKVWFRQRWVNPFLTWDPKMYGGLTSINVNPNMIWKPDIVLYHNI-GFGETGAIYKFDTRATIMHNGYTEWFAPTEIHSICAIDITYFPFDEQFCKMKFGSWSYSGRQLNLTSK--GDSADLS-KYTKSGEWDLLGMRAVRNVVKYSCCPDP------FIDITFTMHIRRKVLFYLTNLIAPCIVLATLTVFSFQLPLESGERIGLVITIWLGLTVFMLVFTENVPRTSEVIPLIGKYSFSVMCVVSCSLIVTCCILKVFNKDPNIKMSSWFKKLI 340
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Nematostella
Match: EDO44896 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUG1])

HSP 1 Score: 157.918 bits (398), Expect = 2.955e-42
Identity = 103/321 (32.09%), Postives = 173/321 (53.89%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPV-CDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYA-------EVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKM 1110
            L+  L +GYN  A PV   NKT++ V   + L QL ++D+  Q++T +VW+   W + +L WDP  + G+ ++ + A +I+ PD++ Y S    F  G+  +   V  +  +G+    + A  +S C++D+  FP+D Q C + F SW  +    +I    A  S  HS +   + EW+++              + +  N  YYA       +VT     +RKP F    LI PC+++  +  L F+LP ESGE++ LS+T+LL++ VFL L +EN+PR SD +P LG+F+   +  V LS++ T  VL++  K+  + +
Sbjct:   15 LLGDLLKGYNKDAHPVPILNKTQYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLLKWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVI-LNHDGVNAWYSPASFRSTCQIDVTFFPFDQQTCFMKFGSWTFEVVDLDIF---ADKSPLHSSQYMKSAEWDLI-------------AASKKRNVEYYACCTYPFSDVTVTWVFRRKPLFYVFNLIVPCLIITGMVLLGFMLPPESGERITLSITVLLAMAVFLQLAAENLPRNSDNVPVLGIFYITVMVEVALSLIATCYVLHIHHKNSGIAV 318
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Nematostella
Match: EDO45564 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSH5])

HSP 1 Score: 152.525 bits (384), Expect = 1.169e-41
Identity = 99/315 (31.43%), Postives = 167/315 (53.02%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFN-ITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMP 1113
            LI  L + Y   A PV +      V +DI   QL DLD   Q+L+  VW+   W +  L+W+P D+ GL+ I + +  ++ PD+I Y ++       M+ F   V  I S+G     A   +KS C++DI  FP+D Q C + F SW    +  N +  ++  D   ++     +GEWE+   P    + KY            Y +VT+ + ++RK  F    LI PC++L  ++  +F+LP  SGE+++L +TILL + VF+L+ +E++PRTS+ IP +  +    +  V +S+L+T +V+ +  K+  + +P
Sbjct:    5 LITTLFKDYQRDARPVYNKSEAVRVSLDIAYSQLIDLDGKNQILSSKVWIRQVWRNPFLSWNPDDYGGLESINVNSNLVWKPDIILYNNIGIGQTGAMYNFDTKVV-IDSDGTNSWYAPTEIKSICQIDITYFPFDAQSCPIIFGSWTYTGNYLNLVNARNQSDLSKYTI----SGEWELKSAPVVRNVVKYSCCKHP------YIDVTYTINIRRKVLFYLNNLILPCMVLAILTVCSFLLPPASGERISLVITILLGLTVFMLVFTESVPRTSEVIPLIAKYSFAVMCEVAVSLLLTCVVMRIYHKNSPMPLP 308
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Nematostella
Match: EDO37425 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFX0])

HSP 1 Score: 150.984 bits (380), Expect = 1.728e-41
Identity = 93/291 (31.96%), Postives = 155/291 (53.26%), Query Frame = 1 
Query:  214 PVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVG 1086
            PV +     +V MD+ L  + D+DE  Q+LT  VWM   W +  + WDP  F G+  +TL   +I+ PD++ Y ++   F +G      ++ R+  NG     A  + K+ C++ ++ FP+D Q C L F SW  D+S  ++          ++     NGEW+V+          Y    D       Y ++TF + L+R+  F    LI P  L+  ++  +F +PIE GE+++  +T+LLS+ VFLLLV+E+IP TS+ +P + +++  S+ LV L+++ T I L V 
Sbjct:   19 PVENTSRPVNVTMDMTLSNVIDIDEKQQILTSCVWMRQEWINERMQWDPKLFGGIKDVTLHTSDIWQPDIVLYNNVFEEF-DGRLDHVSTLVRVYYNGSTHWNAPFIFKTLCKIQVKNFPFDLQECTLKFGSWQYDSSEIDLHYVKTEGKLDNT--RVRNGEWDVIRVKITRNALSYPCCPD-----VVYPDITFIVQLRRRSLFYIFNLIIPNFLIALLAFFSFYIPIECGERISFVITVLLSMTVFLLLVAESIPPTSEALPAIALYYTSSMILVALALVATGITLKVN 301
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Medaka
Match: ENSORLT00000012478.2 (neuronal acetylcholine receptor subunit alpha-7 [Source:NCBI gene;Acc:101155633])

HSP 1 Score: 175.637 bits (444), Expect = 2.334e-47
Identity = 107/322 (33.23%), Postives = 180/322 (55.90%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRIL 1134
            L+  L + YNP+  PV ++     V     L Q+ D+DE  Q+LT + W++M W+D  L W+  ++ G+  +     +++ PD++ Y S H  F+       ++   + S+G  +     +  S C VD+R FP+D QRC L F SW  D  + +I  K+A D  G+      NGEW+++E P       Y   ++       Y +VTF +TL+R+  F  + L+ PCVLL  ++ + F+LP  SGEK++L +T+LLS+ VF+L+V+E +P TSD +P +G +F  ++ +V +SV+ T IVL     + +   MP+++  +L
Sbjct:   28 LLKELLRDYNPMERPVANDSQALTVHFSYTLIQVMDVDEKNQILTTNAWLQMQWYDHYLQWNQSEYPGVKNLRFSPDQVWTPDILLYNSAHDKFDATF----KTNVLVNSSGFCEFLPPGIFVSTCSVDVRWFPFDIQRCELKFGSWTFDGWLLDIQMKEA-DVSGY----MPNGEWDLMEVPGGRHEIFYDCCAEP------YPDVTFVVTLRRRTLFYALNLLIPCVLLSSMTLVVFLLPANSGEKISLGITVLLSLTVFMLMVAEIMPATSDSVPLIGQYFASTMVIVGMSVVATVIVLQFHHHTPNSGPMPRWVHLVL 334
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Medaka
Match: chrnb5b (neuronal acetylcholine receptor subunit beta-2-like [Source:NCBI gene;Acc:101163178])

HSP 1 Score: 172.94 bits (437), Expect = 2.821e-47
Identity = 108/343 (31.49%), Postives = 188/343 (54.81%), Query Frame = 1 
Query:  190 QGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSR---FLCLHHKTHNKFRSGSANSKD 1206
            + YN L  P  +N  +  +++ + L QL +++E  Q++T + W+   W D  L WDP +++G+ +I LP+  I+ PD++ Y +  G +E   +    S A + +NG V     A+ KS C++++R FP+D Q C L F SW  D +  ++       S+   FK   +GEW++V  P            +E  N   Y ++T+   ++RKP F  + LI PC+L+  ++ L F LP + GEK+ L +++LL++ VFLLL+S+ +P TS  +P +G +   ++ LV  S++ +  VLNV  +S     MP ++KR+  ++   FL +        R GS+N ++
Sbjct:   36 ERYNKLIRPAVNNSQQVTIYIQVSLAQLINVNEREQIMTTNCWLTQGWNDYRLMWDPDEYDGIKKIRLPSQHIWLPDIVLYNNADGTYEVSFY----SNAVVSNNGEVAWLPPAIYKSACKIEVRDFPFDQQNCTLKFRSWTYDHTEIDLILLSDYASRD-DFK--PSGEWDIVSLPG---------RKNEDPNDIRYLDITYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLAVPLIGKYLMFAMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKRVFLNQLPSFLFMR-------RPGSSNIRE 355
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Medaka
Match: chrnb5b (neuronal acetylcholine receptor subunit beta-2-like [Source:NCBI gene;Acc:101163178])

HSP 1 Score: 172.94 bits (437), Expect = 3.417e-47
Identity = 108/343 (31.49%), Postives = 188/343 (54.81%), Query Frame = 1 
Query:  190 QGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDV-KMPKFLKRILNSR---FLCLHHKTHNKFRSGSANSKD 1206
            + YN L  P  +N  +  +++ + L QL +++E  Q++T + W+   W D  L WDP +++G+ +I LP+  I+ PD++ Y +  G +E   +    S A + +NG V     A+ KS C++++R FP+D Q C L F SW  D +  ++       S+   FK   +GEW++V  P            +E  N   Y ++T+   ++RKP F  + LI PC+L+  ++ L F LP + GEK+ L +++LL++ VFLLL+S+ +P TS  +P +G +   ++ LV  S++ +  VLNV  +S     MP ++KR+  ++   FL +        R GS+N ++
Sbjct:   36 ERYNKLIRPAVNNSQQVTIYIQVSLAQLINVNEREQIMTTNCWLTQGWNDYRLMWDPDEYDGIKKIRLPSQHIWLPDIVLYNNADGTYEVSFY----SNAVVSNNGEVAWLPPAIYKSACKIEVRDFPFDQQNCTLKFRSWTYDHTEIDLILLSDYASRD-DFK--PSGEWDIVSLPG---------RKNEDPNDIRYLDITYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLAVPLIGKYLMFAMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKRVFLNQLPSFLFMR-------RPGSSNIRE 355
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Medaka
Match: ENSORLT00000023459.2 (neuronal acetylcholine receptor subunit alpha-7 [Source:NCBI gene;Acc:101168927])

HSP 1 Score: 171.014 bits (432), Expect = 1.095e-46
Identity = 107/335 (31.94%), Postives = 181/335 (54.03%), Query Frame = 1 
Query:  133 SISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL 1134
            S+     + +Y  LI    + YNPL  PV ++     V     L Q+ D+DE  Q+LT ++W+++ W D  L W+  D+ G+  +  P  +I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D QRC+L F SW       ++   +A D+ G+     +NGEW++VE P   +   Y    +       Y +VTF + ++R+  +  +  + PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV+ T +VL       D   MP++ + +L
Sbjct:    4 SLQGVHQRRLYKELI----RNYNPLERPVSNDSHSLTVHFSFSLLQIMDVDEKNQVLTTNIWLQLYWKDFYLQWNMSDYPGVTNVRFPDSQIWRPDILLYNSADERFDASF----HTNILVNSSGYCQYLPPGIFKSTCHIDVRWFPFDVQRCDLKFGSWTYGGWSLDLQMINA-DTTGY----IANGEWDLVEVPGQRSERFYDCCKEP------YPDVTFTVVMRRRTLYYGLNFLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMAIVGLSVIATVLVLQYHHHDPDGGHMPQWTRVVL 319
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Medaka
Match: ENSORLT00000023454.2 (neuronal acetylcholine receptor subunit alpha-7 [Source:NCBI gene;Acc:101168927])

HSP 1 Score: 171.4 bits (433), Expect = 1.150e-46
Identity = 104/318 (32.70%), Postives = 175/318 (55.03%), Query Frame = 1 
Query:  184 LKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL 1134
            L + YNPL  PV ++     V     L Q+ D+DE  Q+LT ++W+++ W D  L W+  D+ G+  +  P  +I+ PD++ Y S    F+        +   + S+G  Q     + KS C +D+R FP+D QRC+L F SW       ++   +A D+ G+     +NGEW++VE P   +   Y    +       Y +VTF + ++R+  +  +  + PCVL+  ++ L F+LP +SGEK++L +T+LLS+ VF+LLV+E +P TSD +P +  +F  ++ +V LSV+ T +VL       D   MP++ + +L
Sbjct:   12 LIRNYNPLERPVSNDSHSLTVHFSFSLLQIMDVDEKNQVLTTNIWLQLYWKDFYLQWNMSDYPGVTNVRFPDSQIWRPDILLYNSADERFDASF----HTNILVNSSGYCQYLPPGIFKSTCHIDVRWFPFDVQRCDLKFGSWTYGGWSLDLQMINA-DTTGY----IANGEWDLVEVPGQRSERFYDCCKEP------YPDVTFTVVMRRRTLYYGLNFLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMAIVGLSVIATVLVLQYHHHDPDGGHMPQWTRVVL 314
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Planmine SMEST
Match: SMESG000045280.1 (SMESG000045280.1)

HSP 1 Score: 847.81 bits (2189), Expect = 0.000e+0
Identity = 444/446 (99.55%), Postives = 445/446 (99.78%), Query Frame = 1 
Query:   43 MLFKFGIGVFVLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILNSRFLCLHHKTHNKFRSGSANSKDNNDNEENICEKLTYWRRLATLLDRVFXXXXXXXXXXXXXXXFVQEPAIKKFVGHESGH 1380
            MLFKFGIGVFVLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTF+LPIESGEKVNLSVTILLSVIVFLLLVSENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILNSRFLCLHHKTHNKFRSGSANSKD NDNEENICEKLTYWRRLATLLDRVFLIVYLILAILITLYIFVQEPAIKKFVGHESGH
Sbjct:    1 MLFKFGIGVFVLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFILPIESGEKVNLSVTILLSVIVFLLLVSENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILNSRFLCLHHKTHNKFRSGSANSKD-NDNEENICEKLTYWRRLATLLDRVFLIVYLILAILITLYIFVQEPAIKKFVGHESGH 445
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Planmine SMEST
Match: SMESG000027550.1 (SMESG000027550.1)

HSP 1 Score: 363.999 bits (933), Expect = 1.354e-120
Identity = 187/395 (47.34%), Postives = 267/395 (67.59%), Query Frame = 1 
Query:  145 KTHKSIYLPLIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDS-KGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKDVKMPKFLKRILNS---RFLCLHH-KTHNKFRSGSANSKDNNDNEENICEKLT----------YWRRLATLLDRVF 1284
            +T+ SIY PL+D++ +GYNPLA+P+C      H+ +D+WLYQLFDLDEP Q LT+DVW++++W DC ++WDP ++N + QI  PA +I+HPDL  YQ LHGN+EEGMF+F +S  +I  +G++QLGAQ LLK+FCRV+I  FP+D+Q C +TF++WN+D  +FN+T K   D   GHSF N+SNGEW V +  A +++  + +G+DES     ++EVTF L L+RKP F+K YL+FPC+LL+W++A+TF+LP+ SGEKV L  TILLS+ VFLL++S+ +P TSD IP +  FF   IGLV L ++ T IVLN+  +S  + +P   ++ L S   +F C    K H +F       K++ +    I    T           W +L  LLDRVF
Sbjct:   45 RTNVSIYEPLLDHIFEGYNPLAIPICKPNKPLHMMIDMWLYQLFDLDEPKQELTLDVWIDLNWKDCSISWDPKEYNNIKQIVAPAHDIWHPDLFIYQGLHGNYEEGMFVFRESKVKINYDGVIQLGAQLLLKTFCRVEIAKFPFDSQVCPITFSAWNKDLRVFNMTMKPKHDEDSGHSFVNSSNGEWNVTKLVASDSIKAFHVGADES-QLENFSEVTFTLHLKRKPGFMKTYLVFPCLLLIWVAAITFILPVSSGEKVGLISTILLSLFVFLLIISDYVPHTSDSIPLIAKFFFSCIGLVSLGMIFTVIVLNLSHRSSQIPLPVCFQKFLYSSAAQFFCFSFTKQHKQFTDYQVLFKNSTNATTEISPTWTDGDGNQIDNKQWDQLGKLLDRVF 438
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Planmine SMEST
Match: SMESG000002905.1 (SMESG000002905.1)

HSP 1 Score: 179.104 bits (453), Expect = 2.592e-49
Identity = 118/389 (30.33%), Postives = 208/389 (53.47%), Query Frame = 1 
Query:  124 APVSISNKTHKSIYLPLIDYLK-QGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIF-------NITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRILN---SRFLCLHHKTHNKFRSGSANSKDNNDNEENICEKLTYWR 1254
            A  S + K  K +   L D  +   +N L  P  D+K    V++ I+L Q+ D+DE  Q+L  +VW+++ W D    WDP  +N +  + +PA  ++ PD++ Y S    F+     FP ++  ++ +G +      + KS C+++I+ +P+DTQ+C + F SW  + ++        N T  +    KG++     NGEW+V+ F A  ++ KY    +       Y ++++ L ++R+  +    LI PC+++  ++ L F++P ++GEK++L VTILLS+ VFL++V+E +P TS  IP +GM+F   + +  LS++ T +VLN   +S D + +P+ L +++N   +R L +  K  NK  S    S D   N         Y R
Sbjct:   14 AKESFAGKAEKKLLRHLFDNKRTDAHNILERPAKDDKKSLAVYILIFLMQIIDVDEKNQILHTNVWIDLKWTDYHFVWDPIAYNNITTLVIPANRLWRPDILLYNSADERFDAT---FPANIV-VKYDGEMHTVPPGMFKSTCQINIKWYPFDTQKCKMKFGSWTYEGNLIDLLFFCDNATTCNQTFGKGNAENIMENGEWDVLSFKAIRSVDKYPCCPET------YIDISYYLEIKRRTLYYTFNLIVPCIIISTMALLGFLIPPDAGEKISLGVTILLSLTVFLMMVAEKMPPTSKAIPLIGMYFTCVMIVCSLSLVFTVLVLNFHHRSSDSIDVPESLHKVVNIWLARILFM--KPRNKVASEVFESGDLKQNTGQFKRNAIYNR 390
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Planmine SMEST
Match: SMESG000011827.1 (SMESG000011827.1)

HSP 1 Score: 162.155 bits (409), Expect = 2.470e-43
Identity = 97/323 (30.03%), Postives = 176/323 (54.49%), Query Frame = 1 
Query:  193 GYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKK-DAGDSKGHSFKNA------SNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKS-KDVKMPKFLKRILN 1137
            G+N L  PV D      V   + L Q+ DLDE  Q++  ++W++++W D    W+P +F  +  + LP+ +++ PD++ Y S    F+     +P +V  + + G++ +    + KS C+++I  FP+D Q C + F +W       +   K D G +    + +A       NGEWE+V+ PA      Y    +     S + ++ F + ++RK  +    L+ PC+++  +S L F LP  +GEK+ + VTI+LS+ +FL +V++ +P+TS  +P +G++F   + +   SV+ T +VLN   KS +D +MP +LK ++N
Sbjct:   35 GHNSLERPVVDENQSLEVQFKVTLLQILDLDEKNQVMNTNIWLDITWTDYNFKWNPLEFGNITTLILPSEKVWKPDILMYNSADEKFDGT---YPANVV-VTNQGLMHMVPPGMFKSTCKINITWFPFDQQSCVMKFGTWTYTGDKVDFRLKCDEGSNCTGQYGSADTESFLKNGEWEIVDVPAEKHTETYPCCPE-----SPFIDIKFHVKMRRKALYYIFNLMTPCIIISTMSLLVFTLPPGAGEKITMGVTIMLSLTMFLFMVADKLPQTSGSVPLIGLYFSCIMIMCSFSVVFTVLVLNCHHKSGEDEEMPYWLKVLVN 348
[Close]
BLAST of Acetylcholine receptor subunit alpha-like vs. Planmine SMEST
Match: SMESG000028455.1 (SMESG000028455.1)

HSP 1 Score: 160.614 bits (405), Expect = 2.603e-42
Identity = 99/339 (29.20%), Postives = 180/339 (53.10%), Query Frame = 1 
Query:  172 LIDYLKQGYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDCMLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVARIRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNITKKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEVTFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKXXXXXXXXXXXXXXXXXXXENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEKSKD-VKMPKFLKRIL---NSRFLCLHHKTHNK 1176
            L   L + Y P   PV ++       M I L Q+FD+DE  Q+L  +VW++  W+D  L W+  +F  + ++ +P+ +I+ PD++ Y +   +F + M     ++A ++++G V       LKS C++D+  FP+D+Q C L F SW  D     + K    D   +      NGEW++ +         Y    +       Y +VTF L L+R+  +   ++I+PC+++  ++ L F LP +SGEK+ L +T+LL+  V +L ++E +P TS+ +P + ++    + +  +SV+MT  VLN+  +  +   +PK+++R++   N  F C    T N+
Sbjct:   45 LFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNN-AADFADKMM---PALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMY----VENGEWKLKKTKVLRNNIVYTCCPEP------YYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNR 369
The following BLAST results are available for this feature:
BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CHRNA71.264e-5032.08cholinergic receptor nicotinic alpha 7 subunit [So... [more]
CHRNA76.824e-5032.32cholinergic receptor nicotinic alpha 7 subunit [So... [more]
AC243734.16.824e-5032.32cholinergic receptor nicotinic alpha 7 subunit [So... [more]
AC254952.12.426e-4932.04cholinergic receptor nicotinic alpha 7 subunit [So... [more]
AC254952.12.426e-4932.04cholinergic receptor nicotinic alpha 7 subunit [So... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
acr-191.651e-4230.87AcetylCholine Receptor [Source:UniProtKB/TrEMBL;A... [more]
acr-199.322e-4233.23AcetylCholine Receptor [Source:UniProtKB/TrEMBL;A... [more]
acr-112.914e-4130.77AcetylCholine Receptor [Source:UniProtKB/TrEMBL;A... [more]
unc-381.235e-3930.29Acetylcholine receptor subunit alpha-type unc-38 ... [more]
acr-99.517e-3930.00AcetylCholine Receptor [Source:UniProtKB/TrEMBL;A... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nAChRalpha47.939e-5034.37gene:FBgn0266347 transcript:FBtr0332872[more]
nAChRalpha48.446e-4933.98gene:FBgn0266347 transcript:FBtr0300118[more]
nAChRalpha15.330e-4734.27gene:FBgn0000036 transcript:FBtr0334916[more]
nAChRalpha15.330e-4734.27gene:FBgn0000036 transcript:FBtr0084619[more]
nAChRalpha19.234e-4734.27gene:FBgn0000036 transcript:FBtr0330310[more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrna76.476e-4931.42cholinergic receptor, nicotinic, alpha 7 (neuronal... [more]
chrna74.082e-4831.49cholinergic receptor, nicotinic, alpha 7 (neuronal... [more]
chrna52.635e-4730.56cholinergic receptor, nicotinic, alpha 5 [Source:Z... [more]
chrna52.635e-4730.56cholinergic receptor, nicotinic, alpha 5 [Source:Z... [more]
FO907089.11.178e-4631.67neuronal acetylcholine receptor subunit alpha-7-li... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000021532.19.429e-4931.32cholinergic receptor, nicotinic alpha 7 [Source:NC... [more]
rpap19.777e-4628.64RNA polymerase II associated protein 1 [Source:Xen... [more]
usp161.027e-4531.27ubiquitin specific peptidase 16 [Source:Xenbase;Ac... [more]
usp161.210e-4531.58ubiquitin specific peptidase 16 [Source:Xenbase;Ac... [more]
usp161.744e-4531.58ubiquitin specific peptidase 16 [Source:Xenbase;Ac... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Chrna73.803e-4831.83cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrnb31.059e-4632.13cholinergic receptor, nicotinic, beta polypeptide ... [more]
Chrnb31.237e-4632.13cholinergic receptor, nicotinic, beta polypeptide ... [more]
Chrna52.640e-4427.23cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna93.882e-4433.64cholinergic receptor, nicotinic, alpha polypeptide... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P22770|ACHA7_CHICK1.050e-4932.69Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|P36544|ACHA7_HUMAN3.277e-4932.32Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|Q866A2|ACHA7_MACMU1.839e-4832.04Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|P49582|ACHA7_MOUSE2.661e-4731.83Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|Q05941|ACHA7_RAT2.827e-4731.83Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8JJQ21.261e-11347.64Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8J0041.302e-11347.64Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FL157.360e-11149.86Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FEH21.431e-10746.27Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267DIL72.118e-10746.17Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000053066.18.868e-4932.75neuronal acetylcholine receptor subunit alpha-7-li... [more]
ENSAMXT00000055784.11.356e-4832.75neuronal acetylcholine receptor subunit alpha-7-li... [more]
chrnb3a3.577e-4632.25cholinergic receptor, nicotinic, beta polypeptide ... [more]
chrnb3a7.540e-4632.25cholinergic receptor, nicotinic, beta polypeptide ... [more]
chrnb5a6.048e-4530.28neuronal acetylcholine receptor subunit beta-2 [So... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrna31.372e-4430.57cholinergic receptor, nicotinic, alpha 3 [Source:Z... [more]
chrnb3b1.541e-4430.25cholinergic receptor, nicotinic, beta 3b (neuronal... [more]
chrna2a1.342e-3731.97cholinergic receptor, nicotinic, alpha 2a (neurona... [more]
htr3a2.327e-3429.385-hydroxytryptamine (serotonin) receptor 3A [Sourc... [more]
ENSPMAT00000008550.12.495e-3334.12pep scaffold:Pmarinus_7.0:GL476601:34:38373:1 gene... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO374245.171e-4531.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO469271.250e-4433.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448962.955e-4232.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO455641.169e-4131.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374251.728e-4131.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000012478.22.334e-4733.23neuronal acetylcholine receptor subunit alpha-7 [S... [more]
chrnb5b2.821e-4731.49neuronal acetylcholine receptor subunit beta-2-lik... [more]
chrnb5b3.417e-4731.49neuronal acetylcholine receptor subunit beta-2-lik... [more]
ENSORLT00000023459.21.095e-4631.94neuronal acetylcholine receptor subunit alpha-7 [S... [more]
ENSORLT00000023454.21.150e-4632.70neuronal acetylcholine receptor subunit alpha-7 [S... [more]
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BLAST of Acetylcholine receptor subunit alpha-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000045280.10.000e+099.55SMESG000045280.1[more]
SMESG000027550.11.354e-12047.34SMESG000027550.1[more]
SMESG000002905.12.592e-4930.33SMESG000002905.1[more]
SMESG000011827.12.470e-4330.03SMESG000011827.1[more]
SMESG000028455.12.603e-4229.20SMESG000028455.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031662 ID=SMED30031662|Name=Acetylcholine receptor subunit alpha-like|organism=Schmidtea mediterranea sexual|type=transcript|length=1678bp
AAACATTATAGCTTCGTACTCAGTTGTCATTTACGTCTGTGAATGTTATT
CAAGTTTGGAATTGGTGTTTTTGTGTTGGTGCACATTTGTAGAGTTTGTT
ATTCCAGTGAAAATGACCATAAAGCTCCAGTTAGCATCAGTAACAAAACT
CACAAAAGTATTTATCTGCCCTTGATTGATTATCTAAAACAGGGATATAA
TCCACTGGCCGTTCCAGTATGTGATAACAAAACCAAATTTCACGTTTTTA
TGGATATTTGGTTGTATCAATTGTTTGATCTTGATGAGCCTACTCAAATG
TTAACTATTGATGTTTGGATGGAAATGTCGTGGTTCGACTGTATGCTAAC
ATGGGATCCGCACGATTTCAATGGACTAGATCAAATTACTCTACCTGCTG
GTGAGATTTACCATCCAGATTTAATTTGGTACCAGTCATTACACGGAAAT
TTCGAAGAAGGCATGTTTCTTTTCCCACAATCAGTTGCAAGAATTCGTAG
CAATGGAATGGTTCAACTAGGAGCTCAAGCTTTACTGAAGAGTTTTTGTC
GGGTAGATATTCGTTTATTTCCTTACGATACTCAGAGATGCAACTTGACC
TTTGCATCCTGGAATAGAGATGCGAGCATTTTTAACATAACGAAAAAAGA
TGCAGGAGATTCTAAAGGACATTCTTTCAAAAATGCCAGCAACGGTGAAT
GGGAAGTAGTGGAATTTCCAGCTTATAATACTCTTTCAAAATACAAATTG
GGTTCCGATGAAAGCGGTAACGGTTCTTACTATGCTGAAGTCACTTTTCA
ATTGACTCTTCAAAGAAAACCAACTTTCATAAAAGTTTATTTAATATTCC
CGTGCGTCCTATTGGTATGGATATCAGCGTTGACGTTCGTTCTTCCAATC
GAAAGTGGAGAAAAAGTCAATTTGTCTGTGACGATTTTGTTGTCGGTTAT
TGTTTTTCTGTTGTTGGTTTCAGAAAATATTCCCCGGACTTCTGACGGAA
TTCCTACTTTGGGTATGTTTTTCTGCATGTCAATCGGACTGGTCTGTTTG
TCCGTGCTGATGACAGCCATTGTGTTGAATGTCGGTGAAAAATCAAAGGA
TGTAAAAATGCCAAAATTCTTGAAACGGATTCTCAACAGTAGATTTTTGT
GTTTGCATCATAAAACTCACAATAAATTTCGGAGTGGTTCTGCAAATTCG
AAAGATAACAATGACAATGAAGAGAACATTTGCGAAAAATTGACTTATTG
GCGGAGATTAGCAACGTTATTGGATCGGGTTTTTCTTATCGTTTACCTTA
TCCTAGCAATACTAATTACGTTGTACATTTTTGTCCAGGAACCGGCGATC
AAGAAATTTGTCGGCCACGAATCTGGCCACTGATGGAGCTCGATCTATTT
TTTATACTACAAATCCTGTAAAGCTTGAATTCCGATTTTTTTATCCATGT
TTATAAAATTTGTATTTTTCCACTGTGTTACAAAGTTTAATTGTTTTAAT
GACGCTGCTCGATTTTTGCACCAATGATTATTTTAGATACAAATTTACAA
CGATCCGTTCTTTTTGATTACTTAATCCTGGTGAAATTTATTTACATGAG
GATTAATTTCCAGTAACCAACTGTAAGCCTAAGCCTAAGGGGACCCTCAT
TTCTGTATCTGAAAAATTTTACTGGAGA
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protein sequence of SMED30031662-orf-1

>SMED30031662-orf-1 ID=SMED30031662-orf-1|Name=SMED30031662-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=447bp
MLFKFGIGVFVLVHICRVCYSSENDHKAPVSISNKTHKSIYLPLIDYLKQ
GYNPLAVPVCDNKTKFHVFMDIWLYQLFDLDEPTQMLTIDVWMEMSWFDC
MLTWDPHDFNGLDQITLPAGEIYHPDLIWYQSLHGNFEEGMFLFPQSVAR
IRSNGMVQLGAQALLKSFCRVDIRLFPYDTQRCNLTFASWNRDASIFNIT
KKDAGDSKGHSFKNASNGEWEVVEFPAYNTLSKYKLGSDESGNGSYYAEV
TFQLTLQRKPTFIKVYLIFPCVLLVWISALTFVLPIESGEKVNLSVTILL
SVIVFLLLVSENIPRTSDGIPTLGMFFCMSIGLVCLSVLMTAIVLNVGEK
SKDVKMPKFLKRILNSRFLCLHHKTHNKFRSGSANSKDNNDNEENICEKL
TYWRRLATLLDRVFLIVYLILAILITLYIFVQEPAIKKFVGHESGH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO:0005230extracellular ligand-gated ion channel activity
GO:0001540beta-amyloid binding
GO:0005216ion channel activity
GO:0015464acetylcholine receptor activity
GO:0015643toxic substance binding
GO:0017081chloride channel regulator activity
GO:0022848acetylcholine-gated cation-selective channel activity
GO:0042166acetylcholine binding
GO:0042803protein homodimerization activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006029Neurotrans-gated_channel_TM
IPR027361Acetylcholine_rcpt_TM
IPR006202Neur_chan_lig-bd
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
GO:0005737cytoplasm
GO:0005886plasma membrane
GO:0005892acetylcholine-gated channel complex
GO:0030054cell junction
GO:0030424axon
GO:0030425dendrite
GO:0043204perikaryon
GO:0045202synapse
GO:0045211postsynaptic membrane
Vocabulary: biological process
TermDefinition
GO:0006811ion transport
GO:0006810transport
GO:0000187activation of MAPK activity
GO:0001666response to hypoxia
GO:0006816calcium ion transport
GO:0006874cellular calcium ion homeostasis
GO:0007165signal transduction
GO:0008284positive regulation of cell proliferation
GO:0032720negative regulation of tumor necrosis factor production
GO:0034220ion transmembrane transport
GO:0035094response to nicotine
GO:0045766positive regulation of angiogenesis
GO:0050890cognition
GO:0060078regulation of postsynaptic membrane potential
GO:0060079excitatory postsynaptic potential