General transcription factor II-I repeat domain-containing 2A-like protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031645 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Human
Match: GTF2IRD2 (GTF2I repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30775]) HSP 1 Score: 149.828 bits (377), Expect = 1.494e-47 Identity = 102/294 (34.69%), Postives = 153/294 (52.04%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
E S CIIH ++LCA+ L M+ VM +VVK +N I + L F + LD QYG+LL + E++WLS+G +L+RF E L +I F+ R + +LS++ W+RDLAFL D+T LN LN+ LQ + V M + ++ F KL L + +L N+L HFP LK N S +Y+P ++ L EF+KR DF + + PF S + + +L+ME+I + L ++ K + EF ++ YP + KI + GST F I
Sbjct: 647 ELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGL---NYIPKIAELQTEFQKRLSDFKLYESELTLFSSPF------------STKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLW-GSYPKYKHHCAKILSMFGSTYICEQLFSI 924 HSP 2 Score: 62.003 bits (149), Expect = 1.494e-47 Identity = 34/100 (34.00%), Postives = 58/100 (58.00%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLD--KLVSITTDGAPAL 2062
+ +A + + +L+ + + +S+ +DE D+ + QLAIF+R V FDV EELL + + G G +I+ V+ + N C+D KLVS+ + G PA+
Sbjct: 527 EDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLK--NFCIDWSKLVSVASTGTPAM 624
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Human
Match: GTF2IRD2 (GTF2I repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30775]) HSP 1 Score: 149.058 bits (375), Expect = 2.027e-47 Identity = 102/294 (34.69%), Postives = 153/294 (52.04%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
E S CIIH ++LCA+ L M+ VM +VVK +N I + L F + LD QYG+LL + E++WLS+G +L+RF E L +I F+ R + +LS++ W+RDLAFL D+T LN LN+ LQ + V M + ++ F KL L + +L N+L HFP LK N S +Y+P ++ L EF+KR DF + + PF S + + +L+ME+I + L ++ K + EF ++ YP + KI + GST F I
Sbjct: 809 ELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGL---NYIPKIAELQTEFQKRLSDFKLYESELTLFSSPF------------STKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLW-GSYPKYKHHCAKILSMFGSTYICEQLFSI 1086 HSP 2 Score: 62.3882 bits (150), Expect = 2.027e-47 Identity = 34/100 (34.00%), Postives = 58/100 (58.00%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLD--KLVSITTDGAPAL 2062
+ +A + + +L+ + + +S+ +DE D+ + QLAIF+R V FDV EELL + + G G +I+ V+ + N C+D KLVS+ + G PA+
Sbjct: 689 EDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLK--NFCIDWSKLVSVASTGTPAM 786
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Human
Match: GTF2IRD2B (GTF2I repeat domain containing 2B [Source:HGNC Symbol;Acc:HGNC:33125]) HSP 1 Score: 148.673 bits (374), Expect = 1.594e-46 Identity = 102/294 (34.69%), Postives = 153/294 (52.04%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
E S CIIH ++LCA+ L M+ VM +VVK +N I + L F + LD QYG+LL + E++WLS+G +L+RF E L +I F+ R + +LS++ W+RDLAFL D+T LN LN+ LQ + V M + ++ F KL L + +L N+L HFP LK N S +Y+P ++ L EF+KR DF + + PF S + + +L+ME+I + L ++ K + EF ++ YP + KI + GST F I
Sbjct: 647 ELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGL---NYIPKIAELKTEFQKRLSDFKLYESELTLFSSPF------------STKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLW-GSYPKYKHHCAKILSMFGSTYICEQLFSI 924 HSP 2 Score: 59.6918 bits (143), Expect = 1.594e-46 Identity = 31/98 (31.63%), Postives = 56/98 (57.14%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPAL 2062
+ +A + + +L+ + + +S+ +DE D+ + QLAIF+R V FDV EELL + + G G +I+ V+ + + I +LVS+ + G PA+
Sbjct: 527 EDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAM 624
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Human
Match: GTF2IRD2B (GTF2I repeat domain containing 2B [Source:HGNC Symbol;Acc:HGNC:33125]) HSP 1 Score: 148.288 bits (373), Expect = 2.091e-46 Identity = 102/294 (34.69%), Postives = 153/294 (52.04%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
E S CIIH ++LCA+ L M+ VM +VVK +N I + L F + LD QYG+LL + E++WLS+G +L+RF E L +I F+ R + +LS++ W+RDLAFL D+T LN LN+ LQ + V M + ++ F KL L + +L N+L HFP LK N S +Y+P ++ L EF+KR DF + + PF S + + +L+ME+I + L ++ K + EF ++ YP + KI + GST F I
Sbjct: 814 ELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGL---NYIPKIAELKTEFQKRLSDFKLYESELTLFSSPF------------STKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLW-GSYPKYKHHCAKILSMFGSTYICEQLFSI 1091 HSP 2 Score: 59.6918 bits (143), Expect = 2.091e-46 Identity = 31/98 (31.63%), Postives = 56/98 (57.14%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPAL 2062
+ +A + + +L+ + + +S+ +DE D+ + QLAIF+R V FDV EELL + + G G +I+ V+ + + I +LVS+ + G PA+
Sbjct: 694 EDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAM 791
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Human
Match: ZBED9 (zinc finger BED-type containing 9 [Source:HGNC Symbol;Acc:HGNC:13851]) HSP 1 Score: 108.997 bits (271), Expect = 8.881e-33 Identity = 88/289 (30.45%), Postives = 150/289 (51.90%), Query Frame = 3
Query: 2115 PEFISYHCIIHQQALCAKFLN--MNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGR----HQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVS----SLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGST 2951
PE + HC IH+++L K ++ +NSV+ +VKI+N I+ +L RLF + D ++ + LLLH E+RWLS+GK+L R E+ ++ +FL+G+ Q +V+W LA+L+DI + NDLN +Q K+ M + ++ QKL K + + F NL +N ++S +L+E FE F + +I PF++ + + L+ ++ Q DK L++ + +++S E + + F N YP L ++ALK+ L ST
Sbjct: 841 PECKTTHCFIHRESLAMKKISAELNSVLNDIVKIVNYIKSNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRNELLVFLQGKKPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQKQKLEAWKNRISTDCYDMFHNLTTIINEVGNDLDIAHLRKVISEHLTNLLECFEFYFPSKEDPRIGNLWIQNPFLS-SKDNLNLTVTLQ---DKL-LKLATDEGLKISFENTASLPSFWIKAK-NDYPELAEIALKLLLLFPST 1123 HSP 2 Score: 53.5286 bits (127), Expect = 8.881e-33 Identity = 34/115 (29.57%), Postives = 60/115 (52.17%), Query Frame = 2
Query: 1760 RSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFI-NENNICLDKLVSITTDGAPALTGMHKDFIALCKK 2101
R +A+D QL + YFS+QLDE D+ + L ++VR + D++EE +L T ++Y+ VK++I N+ + V + +DGA ++TG H + + K+
Sbjct: 725 RRIQELANDMEDQLIEQIKLAKYFSLQLDECRDIANMIILLVYVRFEHDD-DIKEEFFFSASLPTNTTSSELYEAVKNYIVNKCGLEFKFCVGVCSDGAASMTGKHSEVVTQIKE 838
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Zebrafish
Match: CR392001.3 (pep chromosome:GRCz11:8:38963323:38965260:-1 gene:ENSDARG00000117159.1 transcript:ENSDART00000181495.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR392001.3) HSP 1 Score: 138.658 bits (348), Expect = 9.561e-51 Identity = 83/240 (34.58%), Postives = 131/240 (54.58%), Query Frame = 3
Query: 2121 FISYHCIIHQQALCAKFLNMNS--VMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGR---HQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLP-IVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMEL 2822
+++HCI+HQ+ALCA+ VM LV++++N I KAL R F+ + D +D +Y +LLLH +VRWLSK ++LRRF L + FL+ + + +L + WL L F+ D+T+ LN LN LQ + + M+ A+ F +KL + ++ L HFP+L+E + YL + + FE RF +F K K + F + P +E ++S G +A LEME+
Sbjct: 274 LLAFHCILHQEALCAQTFPSECMVVMNLVIEMVNKIIAKALNHRQFRALLDEVDSEYSDLLLHNKVRWLSKDEVLRRFVACLEHVKTFLKSKDLIYPQLEDTEWLEKLHFMVDMTSHLNKLNESLQVRGNTALQMLEAVLSFERKLTVFARDVQRGTLSHFPSLREFKESHQDHTINGDYLHNAIVDMQTAFESRFCEFRKEKMTLSFPVTP-----LEIDPSLLSTFPGIIQADLEMEM 508 HSP 2 Score: 65.0846 bits (157), Expect = 9.561e-51 Identity = 37/109 (33.94%), Postives = 63/109 (57.80%), Query Frame = 2
Query: 1775 MASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKK 2101
MA + Q ++++ +S+ DES D A+ R V N+ +EE++K++ L+G T G+DI + V +NEN I + L+S+ TDGAP++ G + F+ L +K
Sbjct: 167 MAGNITEQQIKDINSAPAYSIACDESCDT------ALLCRYV-NSDGPQEEIIKLIPLKGQTRGEDICEAVLKCLNENGINTNHLISVATDGAPSMRGSKRGFVTLLQK 268 HSP 3 Score: 39.2762 bits (90), Expect = 9.561e-51 Identity = 27/103 (26.21%), Postives = 51/103 (49.51%), Query Frame = 3
Query: 1443 CIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVEDXXXXXXXXXXXXXXXXXXXXXXX*HPFASAKF*LLK-KTFEDGEYLKQAFLEVGSYSFT 1748
C++C ++ K+ N+ERHF +H +P+ SE RK + L + K K +A F + + + + K F DG+Y+K++F+ + + F+
Sbjct: 37 CLLCSEKLSNNKKSNVERHFQGRHATFAAEYPVGSE-RKSAIALLVEKLEERKNKFKKWIASPNSTTAASFVATREIIKRGKPFTDGDYMKESFINISEHLFS 138
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Zebrafish
Match: AL928808.1 (pep chromosome:GRCz11:20:17257101:17259573:-1 gene:ENSDARG00000101333.2 transcript:ENSDART00000166397.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL928808.1) HSP 1 Score: 167.933 bits (424), Expect = 8.990e-44 Identity = 109/303 (35.97%), Postives = 163/303 (53.80%), Query Frame = 3
Query: 2082 LLHYVKKIKNYPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQY-GNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQE---LSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNL------KEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIE---LS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGST 2951
L+ K +P F ++HCIIHQ+ +K LN++ +MK V++I+N +R AL R FK + D LD +LL H VRWLS+G +L RF ELL + LFL +H+E L + W+ DLAFL D+ LN LNVDLQ K K + ++ ++ F KL L K +L + D HFP L K EV ST Y ++ +L + FE+RF + + + + F++ PF SG + D+A ++E+I++ E L + +EF V YP ++ ALK+ + GST
Sbjct: 269 LVGLCKADDRFPAFWTFHCIIHQEHWVSKKLNLDHIMKPVLEIVNFVRTHALNHRQFKNLIDELDEDLPSDLLFHCAVRWLSRGHVLSRFFELLNPVKLFLAEKHKEYPELHDPQWISDLAFLVDVLHYLNGLNVDLQGKLKMLPDLVQSVFAFVNKLKLFKTHLQKRDYTHFPTLLKASGQKAEVVKGSTA----RYATLLENLEQSFEERFSNLQQKRQQITFLINPFT-----AESGCLKAPLVEDEAASQLEMIELSEDDRLKSVLREGTVEFWKIVPVERYPNVKQAALKLLSMFGST 562 HSP 2 Score: 30.8018 bits (68), Expect = 8.990e-44 Identity = 15/44 (34.09%), Postives = 29/44 (65.91%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSPGMQKYI 3085
+CE +FS +K +K+ + + LT+ ++ LR+A T Y P ++K +
Sbjct: 564 VCELLFSTLKLVKSKHRSVLTDTHVKELLRVATTEYEPDLKKIV 607 HSP 3 Score: 90.5077 bits (223), Expect = 3.992e-18 Identity = 52/127 (40.94%), Postives = 72/127 (56.69%), Query Frame = 2
Query: 1733 QL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKNKKL 2113
QL H QR D + + L ++L C YFS+ LDES DV DK Q AIFVR V +REELL I+ L+ T G D+ + + + + N+ L KL +I TDGAPA+ G + + LCK + +
Sbjct: 154 QLSRHTVEQRISD-IDNSVETHLLSDLQKCQYFSIALDESCDVQDKPQFAIFVRFVSEDCTIREELLDIVPLKDRTRGIDLKETLMTVVEKANLQLSKLTAIVTDGAPAMLGSERGLVGLCKADDRF 279
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Zebrafish
Match: CR762475.1 (pep chromosome:GRCz11:4:55494751:55498830:1 gene:ENSDARG00000098243.2 transcript:ENSDART00000172605.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR762475.1) HSP 1 Score: 55.0694 bits (131), Expect = 5.326e-7 Identity = 37/125 (29.60%), Postives = 70/125 (56.00%), Query Frame = 2
Query: 1709 KTSILRSWQL*LHCNYQRSEDSMASDTFV--QLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHK 2077
K + ++ Q+ L N +++ M+ TF+ +++N + FS+ LDE+ DV K Q++ VR V + +V+E L++ TLE T G+++ +V + +N + L + DGA ++GM+K
Sbjct: 363 KQASMKKPQVSLLSNRSQNDIIMSLGTFIRSKIQNEIKEAQIFSILLDETTDVSHKEQVSFVVRYVRD-MEVKERFLQVCTLES-TTGKELENVVISLLQDNGLDLKNIRGQGYDGAANMSGMYK 485
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Xenopus
Match: ENSXETT00000016563.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:4:37379994:37381838:-1 gene:ENSXETG00000009412.1 transcript:ENSXETT00000016563.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 161.384 bits (407), Expect = 6.242e-56 Identity = 103/292 (35.27%), Postives = 154/292 (52.74%), Query Frame = 3
Query: 2130 YHCIIHQQALCAKFLNMNSVMKLVVKIINSIRG--KALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRH------QELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPN---LKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
+HCI+HQ+ LC L M +M +V K+ N IRG ++L R FK + LD YG+LLLH VRWLS GK L RF L +I L+L + L++VS+L LAFLTDIT LN LN++LQ +D+NV + + + F KL LLK L +NDL HF + L +E+ + + ++P + LI EF RF DF ++ K P +N +I + K +E+ ++ + S+ + F ++ YP LRD ++++ + GST F
Sbjct: 285 FHCIVHQEVLCGTSLKMADIMDVVTKVTNLIRGGNRSLTHRRFKNFLEELDAAYGDLLLHTNVRWLSAGKCLVRFFALRKEIHLYLSDIKCDSYLLEHLTDVSFLTALAFLTDITQFLNSLNLNLQGRDQNVSQLYSHIAAFRNKLHLLKSFLAKNDLTHFESCCELFQEMKGNGVILNFSQFVPKMDILIHEFNTRFQDFEGMEASFKLFNNP-INTDIAA---------QDTKYHMELCELQGDQFLHSCSEKGVAFFKLLSQEQYPILRDFGMRMASMFGSTYICEKAF 566 HSP 2 Score: 74.7146 bits (182), Expect = 6.242e-56 Identity = 42/102 (41.18%), Postives = 57/102 (55.88%), Query Frame = 2
Query: 1796 QLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKK 2101
+L+N L + YFS+ LDES D+ D QL IFVR V F + EELL+I+ L G T G+DIY VK + + I TDGA A+ G ++ +K
Sbjct: 177 KLQNILRSAPYFSIALDESTDITDTCQLVIFVRSVDQEFHISEELLEIVPLHGSTKGEDIYNAVKATVTKYG-GFSSCTCIVTDGARAMVGRNQGLAGRLRK 277 HSP 3 Score: 25.0238 bits (53), Expect = 6.242e-56 Identity = 12/38 (31.58%), Postives = 22/38 (57.89%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
+CE FS+M F+K+ Y + + L +R++ T+ S
Sbjct: 561 ICEKAFSDMGFIKSKYRNSICDSTLQQIIRISTTSISA 598
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Xenopus
Match: spag1 (sperm associated antigen 1 [Source:Xenbase;Acc:XB-GENE-853609]) HSP 1 Score: 151.369 bits (381), Expect = 8.486e-52 Identity = 100/292 (34.25%), Postives = 144/292 (49.32%), Query Frame = 3
Query: 2130 YHCIIHQQALCAKFLNMNSVMKLVVKIINSIRG--KALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRH------QELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPN---LKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
+HCI+HQ+ LC L M +M +V K+ N IRG ++L R FK + LD YG+LLLH VRWLS GK L RF L +I L+L + L++VS+L LAFLTDIT LN LN++LQ +D+NV + + + F KL LLK L +NDL HF + L +E+ + + ++P + LI EF RF DF G NQF + ++ + K++ + YP LRD ++++ + GST F
Sbjct: 285 FHCIVHQEVLCGTSLKMADIMDVVTKVTNLIRGGNRSLTHRRFKNFLEELDAAYGDLLLHTNVRWLSAGKCLVRFFALRKEIHLYLSDIKCDSYLLEHLTDVSFLTALAFLTDITQFLNSLNLNLQGRDQNVSQLYSHIAAFRNKLHLLKSFLAKNDLTHFESCCELFQEMKGNGVILNFSQFVPKMDILIHEFNTRFQDF----------------------EGNGGNQFLHSCSEKGVAFFKLL-----------------SQEQYPILRDFGMRMASMFGSTYICEKAF 537 HSP 2 Score: 75.0998 bits (183), Expect = 8.486e-52 Identity = 42/102 (41.18%), Postives = 57/102 (55.88%), Query Frame = 2
Query: 1796 QLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKK 2101
+L+N L + YFS+ LDES D+ D QL IFVR V F + EELL+I+ L G T G+DIY VK + + I TDGA A+ G ++ +K
Sbjct: 177 KLQNILRSAPYFSIALDESTDITDTCQLVIFVRSVDQEFHISEELLEIVPLHGSTKGEDIYNAVKATVTKYG-GFSSCTCIVTDGARAMVGRNQGLAGRLRK 277
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Xenopus
Match: ENSXETT00000028445.1 (general transcription factor II-I repeat domain-containing protein 2-like [Source:NCBI gene;Acc:101734469]) HSP 1 Score: 102.449 bits (254), Expect = 2.051e-30 Identity = 93/290 (32.07%), Postives = 142/290 (48.97%), Query Frame = 3
Query: 2133 HCIIHQQALCAKFLNMNSVMKLVVKIINSI---RG--KALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRH------QELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKE---EVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQ---LEFCSHVTPNHYPFLRDVALKISCLIGST 2951
HCI+H++ L L M+ VM++VVKI N I RG A+ ++ FK D L YG+ H W S G+ L RF L +I LFL+ + + L N +L LAFLTD+T L+ L +++ KD+ + + + F KL+LLK+NLI NDL +F + E E + ++ + LIE F RF DF K+ K P + +IS ++ + MEL + + F+ + + F + Y LRD+ALK++ + GST
Sbjct: 275 HCIMHEEMLIGTLLKMSDVMEVVVKISNFILEKRGFITAVTKKKFKTFLDELSAAYGDFDSHKNAYWSSAGQCLFRFFSLRKEIYLFLKDTNYDPILTESLCNEDFLSSLAFLTDLTHYLHSLKKNIEAKDQLITQLYTHVSVFSNKLMLLKLNLISNDLTYFESCNELYREYEECNIFLDFSKFVEKIEVLIENFNLRFQDFSKINSCFKLYNNPLT-------TDIIS-----ERMEYHMELCDL-QADLFFATREELGVPFFRLLPKEKYRNLRDLALKMTSMFGST 551 HSP 2 Score: 49.2914 bits (116), Expect = 2.051e-30 Identity = 33/114 (28.95%), Postives = 55/114 (48.25%), Query Frame = 2
Query: 1760 RSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKK 2101
R +M +L L C YFS+ LDE+ D L IF+R + + F++ E++LK ++L +D+ K + E DK S+ T+G+ ++T AL +K
Sbjct: 154 RRVSAMHQQITQKLHAILKNCCYFSLALDETTDSCGTDLLVIFIRAIDDGFNISEDILKCVSLPKTAKEEDLLNEAKSSLLEYG-GFDKCTSVMTNGSKSMTAKSLGLSALLRK 266 HSP 3 Score: 22.7126 bits (47), Expect = 2.051e-30 Identity = 12/35 (34.29%), Postives = 21/35 (60.00%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTN 3058
+CE FS + +K+ Y ++N+ L L L++TN
Sbjct: 553 ICERAFSELNHLKSNYRNSISNRTLQEILHLSITN 587
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Xenopus
Match: ENSXETT00000010836.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:7:63865670:63866962:-1 gene:ENSXETG00000001503.1 transcript:ENSXETT00000010836.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 61.6178 bits (148), Expect = 4.739e-10 Identity = 35/73 (47.95%), Postives = 47/73 (64.38%), Query Frame = 3
Query: 2343 RFRELLPKISLFLEGR---HQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILL 2552
RF LLP+IS F E + + EL + WL DLAFLTD T+KLN+LN++LQ +DK + + + GQK LL
Sbjct: 121 RFHYLLPEISQFSEEKDELYSELYDYQWLADLAFLTDKTSKLNNLNLELQGQDKTTCIFKHKL---GQKSFLL 190
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Mouse
Match: Gtf2ird2 (GTF2I repeat domain containing 2 [Source:MGI Symbol;Acc:MGI:2149780]) HSP 1 Score: 135.576 bits (340), Expect = 1.078e-43 Identity = 83/238 (34.87%), Postives = 123/238 (51.68%), Query Frame = 3
Query: 2127 SYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM 2831
S CIIH + LCA+ L M VM +VV +N I + L F + LD QYG+LL H ++WL +G +LRRF E L +I F+ R + +LS+ W+ DLAFL D+T LN L+ LQ + V M + ++ F KL L + +L N+L HFP LK + S +Y+P + L EF++R DF + + PF S + + +L+ME+I +
Sbjct: 644 SVRCIIHPEWLCAQKLRMGHVMDVVVDSVNWICSRGLNHGDFTTLLYELDSQYGSLLYHTALKWLGRGLVLRRFFESLEEIDSFMSSRGKPVPQLSSRDWILDLAFLVDMTTHLNTLDASLQGHSQIVTQMYDFIRAFLAKLCLWETHLARNNLAHFPTLKSVSRSESDGL---NYIPKIVELKAEFQRRLSDFKSCESELTLFSSPF------------STTIDSVREELQMEVIDL 866 HSP 2 Score: 63.1586 bits (152), Expect = 1.078e-43 Identity = 33/98 (33.67%), Postives = 57/98 (58.16%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPAL 2062
+ +A + +L+ + + +S+ +DE D+ D QLAIF+R V + FDV EELL + + G G +I+ V+ + + +I KLVS+ + G PA+
Sbjct: 521 EEVAGSLWEKLRQKIRSFVAYSIAIDEITDINDTTQLAIFIRGVDDNFDVSEELLDTVPMTGAKSGNEIFLRVEKSLKKFSIDWSKLVSVASTGTPAM 618
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Mouse
Match: Zbed5 (zinc finger, BED type containing 5 [Source:MGI Symbol;Acc:MGI:1919220]) HSP 1 Score: 89.7373 bits (221), Expect = 4.942e-28 Identity = 58/168 (34.52%), Postives = 86/168 (51.19%), Query Frame = 3
Query: 2115 PEFISYHCIIHQQALCAKFL--NMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGR-----HQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNL 2597
P+ I HC++H Q L K L + VMK V+ +N ++ +L RLF + LD LLLH E RWLS+GK+L+R EL ++ +F + S+ S L+ +A+L DI LN+LN+ LQ + + + + F KL L + L EN P L
Sbjct: 426 PKAIGAHCMLHLQTLAMKTLPQDFQEVMKSVLSSVNFVKASSLNSRLFLQLCSDLDEPSKTLLLHTEGRWLSRGKVLKRIFELRDELKMFFNQKAIRQFEALFSDNSALQKVAYLVDIFTILNELNLSLQGPNSTCLDLSEKIHSFQMKLQLWQKKLDENKFYMLPTL 593 HSP 2 Score: 56.225 bits (134), Expect = 4.942e-28 Identity = 31/87 (35.63%), Postives = 46/87 (52.87%), Query Frame = 2
Query: 1832 SMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIAL 2092
S+QLDES DV + QL ++VR + N D ++E L LE D+++ V F+ ++ I + + TDGAPA G F L
Sbjct: 335 SIQLDESTDVANCLQLMVYVRYI-NDGDFKDEFLCCKPLERTATALDVFEAVDSFLRQHEISWKSICGVCTDGAPATLGCQSGFQRL 420
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Mouse
Match: Zmym6 (zinc finger, MYM-type 6 [Source:MGI Symbol;Acc:MGI:106505]) HSP 1 Score: 82.8037 bits (203), Expect = 6.884e-24 Identity = 59/200 (29.50%), Postives = 100/200 (50.00%), Query Frame = 3
Query: 2133 HCIIHQQALCAKFLN--MNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQELS----NVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKP 2714
HC IH++ L AK L+ ++ ++ +I++ ++ A ++ + + + ++ NL L+ EVRWLS+G+IL R EL +I +FL +H +L+ + W+ LA+L DI + +N LN LQ + N + F ++L + END FP E +++S S I S + E E FH P
Sbjct: 841 HCFIHREHLAAKKLSPCLHEILLQSSQILSFVKNSASDSQMLTILCEEMGSEHVNLPLNAEVRWLSRGRILTRLFELRHEIEIFLNQKHSDLARYFHDEEWIAKLAYLADIFSLINKLNSSLQGTMTTFFNLYNKVDVFQKRLKMWLKRAQENDYGMFPLFSEFLDSSDV-----SVKNIASIIFEHLEGLSQIFHACYP 1035 HSP 2 Score: 49.2914 bits (116), Expect = 6.884e-24 Identity = 22/81 (27.16%), Postives = 48/81 (59.26%), Query Frame = 2
Query: 1826 YFSMQLDESLDVVDKAQLAIFVRMV-FNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALT 2065
+F++Q+DES + + L +VR + ++ DV+EELL + P+ ++++++ +I+ ++ + V TDGA ++T
Sbjct: 739 WFALQVDESSEATEVPLLLCYVRFIDYDRGDVKEELLFCTEMPSPSTDLEVFELINKYIDSRSLNWNHCVGFCTDGAASMT 819
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Mouse
Match: Zmym6 (zinc finger, MYM-type 6 [Source:MGI Symbol;Acc:MGI:106505]) HSP 1 Score: 82.8037 bits (203), Expect = 7.526e-24 Identity = 59/200 (29.50%), Postives = 100/200 (50.00%), Query Frame = 3
Query: 2133 HCIIHQQALCAKFLN--MNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQELS----NVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKP 2714
HC IH++ L AK L+ ++ ++ +I++ ++ A ++ + + + ++ NL L+ EVRWLS+G+IL R EL +I +FL +H +L+ + W+ LA+L DI + +N LN LQ + N + F ++L + END FP E +++S S I S + E E FH P
Sbjct: 933 HCFIHREHLAAKKLSPCLHEILLQSSQILSFVKNSASDSQMLTILCEEMGSEHVNLPLNAEVRWLSRGRILTRLFELRHEIEIFLNQKHSDLARYFHDEEWIAKLAYLADIFSLINKLNSSLQGTMTTFFNLYNKVDVFQKRLKMWLKRAQENDYGMFPLFSEFLDSSDV-----SVKNIASIIFEHLEGLSQIFHACYP 1127 HSP 2 Score: 49.2914 bits (116), Expect = 7.526e-24 Identity = 22/81 (27.16%), Postives = 48/81 (59.26%), Query Frame = 2
Query: 1826 YFSMQLDESLDVVDKAQLAIFVRMV-FNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALT 2065
+F++Q+DES + + L +VR + ++ DV+EELL + P+ ++++++ +I+ ++ + V TDGA ++T
Sbjct: 831 WFALQVDESSEATEVPLLLCYVRFIDYDRGDVKEELLFCTEMPSPSTDLEVFELINKYIDSRSLNWNHCVGFCTDGAASMT 911
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Mouse
Match: Epm2aip1 (EPM2A (laforin) interacting protein 1 [Source:MGI Symbol;Acc:MGI:1925031]) HSP 1 Score: 65.4698 bits (158), Expect = 3.110e-13 Identity = 66/297 (22.22%), Postives = 126/297 (42.42%), Query Frame = 3
Query: 2124 ISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVR----WLSKGKILRRFRELLPKISLFL---EGRHQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFP-------NLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
I Y +H + L + +++N ++ + + + I+ + ++R F+ + + ++G + R WL +GK L+ L +I FL S+ WL D FL DI L +++ +LQ + F KL L+ ++ E +L FP LK++ F + Y ++S L ++FE+ F D +K ++ PF + + IS + K Q +L + K+ +F + ++ YP ++ VA K++ L S + F
Sbjct: 277 IHYSGFLHLELLSSYDVDINQIINTISEWVVMIKTRGVRRPEFQPLLTESESEHGE---RVNGRCLNNWLRRGKTLKLIFSLRKEIEAFLVSVGATTVHFSDKQWLCDFGFLVDIMDYLREISEELQISKVFAAAAFERICTFEGKLSSLQRHMEEVNLTDFPAFSIIVDELKQQFKEDQKIFDPDRYQMVISRLQKDFERHFKDLRFIKKDLELFSNPF---SFKPEYAPISVRVELTKLQANTDLWNEYRV-----KDLGQFYAGLSGEAYPIIKGVAYKVASLFDSNQICDKAF 562 HSP 2 Score: 30.4166 bits (67), Expect = 3.110e-13 Identity = 24/111 (21.62%), Postives = 50/111 (45.05%), Query Frame = 2
Query: 1772 SMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
S+ S+ QL N +S+ LD+ V + L +F+R V +V+E+LL I+ L + + + + + L ++V +TT + G + ++ ++
Sbjct: 157 SIDSNLRSQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGRDLEVQEDLLTIINLTHHFSVGALMSAILEALQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREK 267
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. UniProt/SwissProt
Match: sp|Q86UP8|GTD2A_HUMAN (General transcription factor II-I repeat domain-containing protein 2A OS=Homo sapiens OX=9606 GN=GTF2IRD2 PE=1 SV=3) HSP 1 Score: 149.828 bits (377), Expect = 6.639e-47 Identity = 102/294 (34.69%), Postives = 153/294 (52.04%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
E S CIIH ++LCA+ L M+ VM +VVK +N I + L F + LD QYG+LL + E++WLS+G +L+RF E L +I F+ R + +LS++ W+RDLAFL D+T LN LN+ LQ + V M + ++ F KL L + +L N+L HFP LK N S +Y+P ++ L EF+KR DF + + PF S + + +L+ME+I + L ++ K + EF ++ YP + KI + GST F I
Sbjct: 647 ELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGL---NYIPKIAELQTEFQKRLSDFKLYESELTLFSSPF------------STKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLW-GSYPKYKHHCAKILSMFGSTYICEQLFSI 924 HSP 2 Score: 62.003 bits (149), Expect = 6.639e-47 Identity = 34/100 (34.00%), Postives = 58/100 (58.00%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLD--KLVSITTDGAPAL 2062
+ +A + + +L+ + + +S+ +DE D+ + QLAIF+R V FDV EELL + + G G +I+ V+ + N C+D KLVS+ + G PA+
Sbjct: 527 EDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLK--NFCIDWSKLVSVASTGTPAM 624
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. UniProt/SwissProt
Match: sp|A4IFA3|GT2D2_BOVIN (General transcription factor II-I repeat domain-containing protein 2 OS=Bos taurus OX=9913 GN=GTF2IRD2 PE=2 SV=1) HSP 1 Score: 148.288 bits (373), Expect = 8.724e-47 Identity = 100/288 (34.72%), Postives = 152/288 (52.78%), Query Frame = 3
Query: 2136 CIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
CIIH ++LCA+ L M+ +M +VV +N I + L F + LDCQYG+LL + E++WLS+G +L+RF E L +I F+ R + +LS+ W++DLAFL D+T LN LN+ LQ + V M + ++ F KL L + +L N+L HFP LK N S +Y+P + L EF+KR DF + + PF ++ IE++ + L+ME+I + L ++ K + EF H+ YP + KI + GST F I
Sbjct: 654 CIIHPESLCAQKLKMDHIMSVVVNAVNWICSRGLNHSEFTTLLYELDCQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSQDWIKDLAFLVDMTMHLNTLNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLARNNLAHFPTLKSVSRNESDGL---NYIPKIVELKTEFQKRLSDFKLYESELTLFSSPF-SMKIESV-----------QEALQMEVIDLQCNTVLKTKYDKVGIPEFYKHLW-GSYPKYKIHCAKILSMFGSTYICEQLFSI 925 HSP 2 Score: 63.1586 bits (152), Expect = 8.724e-47 Identity = 33/98 (33.67%), Postives = 57/98 (58.16%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPAL 2062
+ +A + + +L+ + + +S+ +DE D+ + QLAIF+R V FDV EELL + + G G +I+ V+ + + NI KLVS+ + G PA+
Sbjct: 528 EDVAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFNIDWSKLVSVASTGTPAM 625
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. UniProt/SwissProt
Match: sp|Q6EKJ0|GTD2B_HUMAN (General transcription factor II-I repeat domain-containing protein 2B OS=Homo sapiens OX=9606 GN=GTF2IRD2B PE=1 SV=1) HSP 1 Score: 148.673 bits (374), Expect = 7.081e-46 Identity = 102/294 (34.69%), Postives = 153/294 (52.04%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
E S CIIH ++LCA+ L M+ VM +VVK +N I + L F + LD QYG+LL + E++WLS+G +L+RF E L +I F+ R + +LS++ W+RDLAFL D+T LN LN+ LQ + V M + ++ F KL L + +L N+L HFP LK N S +Y+P ++ L EF+KR DF + + PF S + + +L+ME+I + L ++ K + EF ++ YP + KI + GST F I
Sbjct: 647 ELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGL---NYIPKIAELKTEFQKRLSDFKLYESELTLFSSPF------------STKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLW-GSYPKYKHHCAKILSMFGSTYICEQLFSI 924 HSP 2 Score: 59.6918 bits (143), Expect = 7.081e-46 Identity = 31/98 (31.63%), Postives = 56/98 (57.14%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPAL 2062
+ +A + + +L+ + + +S+ +DE D+ + QLAIF+R V FDV EELL + + G G +I+ V+ + + I +LVS+ + G PA+
Sbjct: 527 EDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAM 624
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. UniProt/SwissProt
Match: sp|Q99NI3|GT2D2_MOUSE (General transcription factor II-I repeat domain-containing protein 2 OS=Mus musculus OX=10090 GN=Gtf2ird2 PE=2 SV=1) HSP 1 Score: 135.576 bits (340), Expect = 6.578e-43 Identity = 83/238 (34.87%), Postives = 123/238 (51.68%), Query Frame = 3
Query: 2127 SYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQ---ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM 2831
S CIIH + LCA+ L M VM +VV +N I + L F + LD QYG+LL H ++WL +G +LRRF E L +I F+ R + +LS+ W+ DLAFL D+T LN L+ LQ + V M + ++ F KL L + +L N+L HFP LK + S +Y+P + L EF++R DF + + PF S + + +L+ME+I +
Sbjct: 644 SVRCIIHPEWLCAQKLRMGHVMDVVVDSVNWICSRGLNHGDFTTLLYELDSQYGSLLYHTALKWLGRGLVLRRFFESLEEIDSFMSSRGKPVPQLSSRDWILDLAFLVDMTTHLNTLDASLQGHSQIVTQMYDFIRAFLAKLCLWETHLARNNLAHFPTLKSVSRSESDGL---NYIPKIVELKAEFQRRLSDFKSCESELTLFSSPF------------STTIDSVREELQMEVIDL 866 HSP 2 Score: 63.1586 bits (152), Expect = 6.578e-43 Identity = 33/98 (33.67%), Postives = 57/98 (58.16%), Query Frame = 2
Query: 1769 DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPAL 2062
+ +A + +L+ + + +S+ +DE D+ D QLAIF+R V + FDV EELL + + G G +I+ V+ + + +I KLVS+ + G PA+
Sbjct: 521 EEVAGSLWEKLRQKIRSFVAYSIAIDEITDINDTTQLAIFIRGVDDNFDVSEELLDTVPMTGAKSGNEIFLRVEKSLKKFSIDWSKLVSVASTGTPAM 618
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. UniProt/SwissProt
Match: sp|Q6R2W3|SCND3_HUMAN (SCAN domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZBED9 PE=2 SV=1) HSP 1 Score: 108.612 bits (270), Expect = 5.173e-32 Identity = 88/289 (30.45%), Postives = 150/289 (51.90%), Query Frame = 3
Query: 2115 PEFISYHCIIHQQALCAKFLN--MNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGR----HQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVS----SLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGST 2951
PE + HC IH+++L K ++ +NSV+ +VKI+N I+ +L RLF + D ++ + LLLH E+RWLS+GK+L R E+ ++ +FL+G+ Q +V+W LA+L+DI + NDLN +Q K+ M + ++ QKL K + + F NL +N ++S +L+E FE F + +I PF++ + + L+ ++ Q DK L++ + +++S E + + F N YP L ++ALK+ L ST
Sbjct: 992 PECKTTHCFIHRESLAMKKISAELNSVLNDIVKIVNYIKSNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRNELLVFLQGKKPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQKQKLEAWKNRISTDCYDMFHNLTTIINEVGNDLDIAHLRKVISEHLTNLLECFEFYFPSKEDPRIGNLWIQNPFLS-SKDNLNLTVTLQ---DKL-LKLATDEGLKISFENTASLPSFWIKAK-NDYPELAEIALKLLLLFPST 1274 HSP 2 Score: 53.5286 bits (127), Expect = 5.173e-32 Identity = 34/115 (29.57%), Postives = 60/115 (52.17%), Query Frame = 2
Query: 1760 RSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFI-NENNICLDKLVSITTDGAPALTGMHKDFIALCKK 2101
R +A+D QL + YFS+QLDE D+ + L ++VR + D++EE +L T ++Y+ VK++I N+ + V + +DGA ++TG H + + K+
Sbjct: 876 RRIQELANDMEDQLIEQIKLAKYFSLQLDECRDIANMIILLVYVRFEHDD-DIKEEFFFSASLPTNTTSSELYEAVKNYIVNKCGLEFKFCVGVCSDGAASMTGKHSEVVTQIKE 989
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. TrEMBL
Match: A0A3Q2R058 (Uncharacterized protein OS=Fundulus heteroclitus OX=8078 PE=4 SV=1) HSP 1 Score: 214.927 bits (546), Expect = 1.427e-100 Identity = 116/287 (40.42%), Postives = 173/287 (60.28%), Query Frame = 3
Query: 2109 NYPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRH---QELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSS--TPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMI-ELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGST 2951
++P+F++YHC+IHQQAL K +N+N VM +VV++INSIR KALQ RLFK + D L G+LLLH +VRWLS+GK+L+RF +LLP+I F+E R+ +ELS+ WL DL FLTD+TAK+N LN +LQ KD+++ MI+A+ F KL + L L HF NL++ S F E Y + + EF RF + ++ + FI+ PF+ ++E ++ F ++ME++ I ++ + F V+ +P L AL++S IGST
Sbjct: 301 DFPDFVNYHCVIHQQALVGKVVNLNHVMTVVVRLINSIRAKALQHRLFKALLDELHAACGDLLLHADVRWLSRGKVLQRFVDLLPEIKTFMETRNEECEELSDDQWLLDLGFLTDLTAKMNALNNELQGKDRHLPHMISAVNAFKAKLGVWNTQLKNGRLTHFSNLEKMSQGISDKDAFHPEDYCGHLDKVAAEFSHRFGELDAMEDVAAFILNPFLTTDVEQVAAKFQQVFALPNG-VDMEMLDSINDIELKGRSGDGNFWGIVSREKFPLLTSCALRVSAYIGST 586 HSP 2 Score: 132.494 bits (332), Expect = 1.427e-100 Identity = 79/195 (40.51%), Postives = 115/195 (58.97%), Query Frame = 2
Query: 1583 SLNYQQTFFKKQAGKNEVATLASFRVCKVLT-IKKNI*RW*IFKTSI--------------------LRSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
SL QQ+ F K A +++ AT ASFR+ +L KK IFK ++ LRS QL L+ +R E+ M++D Q+ +L C YFS+Q DESLDV+D AQL +FVRM F +E+LL +L L+ T G+DIY+ K ++ +N+I +DKLV++TTDG PA+ G+ F+ALC+ +
Sbjct: 106 SLKTQQSLFTKPAAQHKAATEASFRISHLLAKHKKPFTDGDIFKEAMAITADTIFNSFSNKDDIKTALRSIQLGLNTVARRVEE-MSADVDRQVLADLSHCEYFSLQFDESLDVMDTAQLVVFVRMAFPDATTKEDLLTLLHLKERTRGEDIYKAFKTYVCDNDIPIDKLVAVTTDGVPAMRGVRSGFVALCRND 299 HSP 3 Score: 57.3806 bits (137), Expect = 1.427e-100 Identity = 33/75 (44.00%), Postives = 41/75 (54.67%), Query Frame = 3
Query: 1371 AVTMAKKRKNYHFHEE-----FFIYVND--ICIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVED 1574
A KK K YHFHEE F + D IC++C+ ++A+ KR NLERH NT H FP S IR KV +
Sbjct: 28 AAAPRKKSKTYHFHEEWEEEFVFTMLKDKCICMLCHQTLALSKRGNLERHHNTNHVKFKDSFPAKSAIRAGKVAE 102 HSP 4 Score: 36.965 bits (84), Expect = 1.427e-100 Identity = 19/38 (50.00%), Postives = 29/38 (76.32%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
LCE FS MK +K+ Y ++L++K+L +CLRLA ++Y P
Sbjct: 588 LCEMAFSQMKIIKSKYRSRLSDKHLTDCLRLAASSYEP 625
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. TrEMBL
Match: A0A3P9D7F1 (Uncharacterized protein OS=Maylandia zebra OX=106582 PE=4 SV=1) HSP 1 Score: 221.476 bits (563), Expect = 2.483e-85 Identity = 119/298 (39.93%), Postives = 180/298 (60.40%), Query Frame = 3
Query: 2112 YPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFL----EGRHQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTP---FSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFV-NINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
+P+F++YHCIIHQQALCAK LNM +M + KI SIR ++LQRRLF+ + DC + LLLH +VRWLS+GK L+RFREL P+I F + + +L++ WL DLAFLTD+T LNDLN+ LQ KDK V+ MI+++ F +K+ L + L +DL +F NL E+ Y + + + EF+KRF DF ++P+ F+ YPF + ++++L+ I+ F + + +E E++ + IEL S++ +F + +T YP +R A ++ L GST F
Sbjct: 156 FPDFLNYHCIIHQQALCAKMLNMKEIMNVATKIACSIRARSLQRRLFRAHLEKADCDHSELLLHTDVRWLSRGKFLQRFRELCPEIKEFFRVAGQAEYMQLNDGQWLLDLAFLTDLTNMLNDLNLQLQGKDKTVINMISSVNAFKRKMQHLSLKLQRHDLINFQNLASELEMQGMACLQLDSARYTEQIDNCLSEFDKRFQDFSLLEPVATFMCYPFREDADVDSLASKIAKLFHLNSSAVEDEILTLQADIELK---SRDHGQFWNLLTEVKYPNMRKCAASLTALFGSTYLCESSF 450 HSP 2 Score: 108.612 bits (270), Expect = 2.483e-85 Identity = 60/131 (45.80%), Postives = 84/131 (64.12%), Query Frame = 2
Query: 1712 TSILRSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
TS +++ QL +R E +MA D QL ++ C FS+QLDES DV D AQ+ IF+RMVF +EELL +L ++ T G+DI+Q K+FI + + + KLVSITTDGAPA+ G FIA C+++
Sbjct: 24 TSSIKALQLSRSTVTRRCE-AMAEDLTQQLWKDIGDCQCFSLQLDESTDVSDTAQVCIFIRMVFTDITAKEELLTVLPMKEQTRGEDIFQSFKNFIEKTQLPVYKLVSITTDGAPAMVGRLNGFIAKCRQD 153 HSP 3 Score: 39.6614 bits (91), Expect = 2.483e-85 Identity = 20/38 (52.63%), Postives = 31/38 (81.58%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
LCES FS+M +K+ Y + +T+++L+ CLRLAV++YSP
Sbjct: 445 LCESSFSHMNIIKSKYRSTMTDEHLEVCLRLAVSSYSP 482
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. TrEMBL
Match: A0A3B3HZV5 (Uncharacterized protein OS=Oryzias latipes OX=8090 PE=4 SV=1) HSP 1 Score: 216.468 bits (550), Expect = 3.009e-84 Identity = 116/306 (37.91%), Postives = 183/306 (59.80%), Query Frame = 3
Query: 2091 YVKKIKN---YPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQELS---NVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSC-----ESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMI-ELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
++ + KN +P+F+ YHCIIHQQA+CAK + VM VVKIINSIR KA Q R+FK + D L +YG+LLLH E+RWLS+G+IL+RF LL +I F++ + ++ S + W+ DLAFLTD+T LN LN +LQ KDK V I+A+ F KL + L + + HFP+++ +N++ + + + Y +++ L +EFE RF DF +++P V F+ PF+ +++ + + +S F + +EME++ + +L + ++ F V Y + A+KI+C GST F
Sbjct: 263 FIAQCKNDPDFPKFLHYHCIIHQQAICAKVTGFDHVMTPVVKIINSIRSKAKQHRMFKMLMDELSAEYGDLLLHTEIRWLSRGRILQRFLSLLGEIKEFMKSKGEDTSLLEDPEWVLDLAFLTDLTGNLNHLNRELQGKDKTVAHTISAVNAFRAKLSIFSTQLQKKKMLHFPSVQAALNDNVSASAALNEAVKKYSQVINRLGQEFEDRFCDFEQLEPCVSFVTNPFMQVDVTSTAEQLSALFTLNAGDVEMEILTLQNDLLLKAHQSAPNFWCLVDQEKYSGVCTAAMKIACFFGSTYLCESAF 568 HSP 2 Score: 107.457 bits (267), Expect = 3.009e-84 Identity = 80/203 (39.41%), Postives = 106/203 (52.22%), Query Frame = 2
Query: 1553 QKEEG*GSEKSLNYQQTFFKKQAGKNEVATLASFRVCKVLTIKKN-------------I*RW*IFK--------TSILRSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCK 2098
+ E+ G + +L+ Q+TFF + A K+ AT ASFR L K + IFK S L QL R S++ + +L +L C +FS+Q DES+D AQL IF+RMVF F +EELL +L L+ T G DIY VK+F E + + KLVS+TTDGAPA+TG H FIA CK
Sbjct: 67 RTEKARGLKAALDMQRTFFTRPAKKSHNATEASFRAAHFLIKNKKPFSDGEVLKEAMMLVANTIFKDEKYAPDVISTLSDVQL-GASTIARRVTSLSENLTEKLDRDLAACRWFSVQCDESVDSASTAQLMIFIRMVFEDFSTKEELLTLLPLKTTTRGVDIYTTVKNFFVEKKVPVQKLVSVTTDGAPAMTGRHVGFIAQCK 268 HSP 3 Score: 42.3578 bits (98), Expect = 3.009e-84 Identity = 23/38 (60.53%), Postives = 30/38 (78.95%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
LCES FSNM F+KN + T LT+ +L + LR+AV+NYSP
Sbjct: 563 LCESAFSNMNFIKNKHRTCLTDAHLQDSLRIAVSNYSP 600
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. TrEMBL
Match: A0A498MQH6 (General transcription factor II-I repeat domain-containing 2A-like protein OS=Labeo rohita OX=84645 GN=ROHU_023746 PE=4 SV=1) HSP 1 Score: 205.297 bits (521), Expect = 3.780e-83 Identity = 122/298 (40.94%), Postives = 175/298 (58.72%), Query Frame = 3
Query: 2112 YPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLE-GRHQELSN---VSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEV---NNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFV-NINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
+P+F++YHCIIHQQALCAK LNM +M + KI SIR ++LQRRLF+ + DC + LLLH +VRWLS+GK L+RFREL P+I FL +H E S WL DLAFLTD+T LNDLN++LQ KDK V MI+++ F +K+ L +DL +F NL E+ S Y + + + EF+KRF DF ++PI F+ YPF + + +L+ I+ F + + +E E++ + I+L S+ +F + +T YP +R A ++ L GST F
Sbjct: 251 FPDFLNYHCIIHQQALCAKMLNMKEIMDVATKIACSIRARSLQRRLFRAHLENADCDHSELLLHTDVRWLSRGKFLQRFRELCPEIKEFLRVAKHAEYSQLNDNLWLLDLAFLTDLTNMLNDLNLELQGKDKTVTNMISSVNAFKRKMQHFSSKLQRHDLANFQNLVSELEMQGKSCVQLDNARYKEQIDNCLSEFDKRFQDFALLEPIATFMCYPFQEDAEVVSLASKIATLFHLNSSGVEDEILTLQADIQLK---SRAHGQFWNLLTEEKYPNMRKCATSLTALFGSTYLCESAF 545 HSP 2 Score: 117.472 bits (293), Expect = 3.780e-83 Identity = 77/194 (39.69%), Postives = 108/194 (55.67%), Query Frame = 2
Query: 1586 LNYQQTFFKKQAGKNEVATLASFRVCKVLTIKKNI*R----------------W*IFKT-----SILRSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
L+ QQ+FF + K AT ASFRV ++ K + + FK S +++ QL +RSE +MA D QL ++ C FS+QLDES DV D AQL IF+RMVFN +EELL +L ++ T G+DI+Q K+F+ + + + KLVSITTDGAPA+ G FIA C+++
Sbjct: 56 LSGQQSFFSQLTSKARAATEASFRVSHLIVKNKKSFQDGEMVKEAFVEAADSLFRDFKNKPEILSSIKALQLSRSTVTRRSE-AMAEDLTQQLWKDVTDCECFSLQLDESTDVSDTAQLCIFIRMVFNDMTAKEELLTVLPMKEHTRGEDIFQSFKNFMEKTRLPVCKLVSITTDGAPAMVGRSNGFIAKCRED 248 HSP 3 Score: 39.6614 bits (91), Expect = 3.780e-83 Identity = 19/38 (50.00%), Postives = 30/38 (78.95%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
LCES FS+MK +K+ Y + +T+ +L+ CLRLA+++Y P
Sbjct: 540 LCESAFSHMKIIKSKYRSTMTDDHLEVCLRLAISSYCP 577 HSP 4 Score: 63.1586 bits (152), Expect = 2.627e-6 Identity = 38/103 (36.89%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 1440 ICIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVEDXXXXXXXXXXXXXXXXXXXXXXX*HPFASAKF*LL-KKTFEDGEYLKQAFLEVGSYSF 1745
IC+IC S +A+ K+ N+ERHF T H+N +T FP SE+RK++V++LK + +K + F + + KK+F+DGE +K+AF+E F
Sbjct: 7 ICLICQSVIAIPKKGNVERHFRTVHKNYDTDFPPKSELRKRRVKELKSQLSGQQSFFSQLTSKARAATEASFRVSHLIVKNKKSFQDGEMVKEAFVEAADSLF 109
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. TrEMBL
Match: A0A498NXL4 (General transcription factor II-I repeat domain-containing 2A-like protein OS=Labeo rohita OX=84645 GN=ROHU_003188 PE=4 SV=1) HSP 1 Score: 202.216 bits (513), Expect = 1.516e-82 Identity = 121/298 (40.60%), Postives = 174/298 (58.39%), Query Frame = 3
Query: 2112 YPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLE-GRHQELSN---VSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEV---NNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFV-NINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
+P+ ++YHCIIHQQALCAK LNM +M + KI SIR ++LQRRLF+ + DC + LLLH +VRWLS+GK L+RFREL P+I FL +H E S WL DLAFLTD+T LNDLN++LQ KDK V MI+++ F +K+ L +DL +F NL E+ S Y + + + EF+KRF DF ++PI F+ YPF + + +L+ I+ F + + +E E++ + I+L S+ +F + +T YP +R A ++ L GST F
Sbjct: 251 FPDSLNYHCIIHQQALCAKMLNMKEIMDVATKIACSIRARSLQRRLFRAHLENADCDHSELLLHTDVRWLSRGKFLQRFRELCPEIKEFLRVAKHAEYSQLNDNLWLLDLAFLTDLTNMLNDLNLELQGKDKTVTNMISSVNAFKRKMQHFSSKLQRHDLANFQNLVSELEMQGKSCVQLDNARYKEQIDNCLSEFDKRFQDFALLEPIATFMCYPFQEDAEVVSLASKIATLFHLNSSGVEDEILTLQADIQLK---SRAHGQFWNLLTEEKYPNMRKCATSLTALFGSTYLCESAF 545 HSP 2 Score: 118.242 bits (295), Expect = 1.516e-82 Identity = 78/194 (40.21%), Postives = 109/194 (56.19%), Query Frame = 2
Query: 1586 LNYQQTFFKKQAGKNEVATLASFRVCKVLTIKK------------------NI*RW*IFKTSIL---RSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
L+ QQ+FF + K + AT ASFRV ++ K ++ R K IL ++ QL +RSE +MA D QL ++ C FS+QLDES DV D AQL IF+RMVFN +EELL +L ++ T G+DI+Q K+F+ + + + KLVSITTDGAPA+ G FIA C+++
Sbjct: 56 LSGQQSFFSQLTSKGKAATEASFRVSHLIVKNKKSFQDGEMVKEAFVEAADSLFRDFKNKPEILSSIKALQLSRSTVTRRSE-AMAEDLTQQLWKDITDCECFSLQLDESTDVSDTAQLCIFIRMVFNDMTAKEELLTVLPMKEHTRGEDIFQSFKNFMEKTRLPVCKLVSITTDGAPAMVGRSNGFIAKCRED 248 HSP 3 Score: 39.6614 bits (91), Expect = 1.516e-82 Identity = 19/38 (50.00%), Postives = 30/38 (78.95%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
LCES FS+MK +K+ Y + +T+ +L+ CLRLA+++Y P
Sbjct: 540 LCESAFSHMKIIKSKYRSTMTDDHLEVCLRLAISSYCP 577 HSP 4 Score: 63.1586 bits (152), Expect = 3.174e-6 Identity = 39/103 (37.86%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 1440 ICIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVEDXXXXXXXXXXXXXXXXXXXXXXX*HPFASAKF*LL-KKTFEDGEYLKQAFLEVGSYSF 1745
IC+IC S +A+ K+ N+ERHF T H+N +T FP SE+RK++V++LK + +K K F + + KK+F+DGE +K+AF+E F
Sbjct: 7 ICLICQSVIAIPKKGNVERHFRTVHKNYDTDFPPKSELRKRRVKELKSQLSGQQSFFSQLTSKGKAATEASFRVSHLIVKNKKSFQDGEMVKEAFVEAADSLF 109
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000039226.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000099.1:564912:568121:1 gene:ENSAMXG00000042173.1 transcript:ENSAMXT00000039226.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 202.986 bits (515), Expect = 5.013e-84 Identity = 124/295 (42.03%), Postives = 179/295 (60.68%), Query Frame = 3
Query: 2112 YPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGR---HQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSST--PFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
+P F+SYHC+IHQQAL +K ++ + VM +VVKI+NSIR KALQ RLFK + D LD +YG+L+LH +VRWLS+GK+L+RF LLP+I FL+ R ++EL++ +WL DLAFLTD+T+KLN+LN +LQ KD +V M++A+ F KL L L L HF N+ + +NN S F E++ ++ L EEF KRF + + K I++ + F + E +GV +ME+I + IE+ + +F V+ YP L ALK+ GST + F
Sbjct: 271 FPAFVSYHCVIHQQALASKVVDFSHVMTVVVKIVNSIRAKALQHRLFKSLLDELDAEYGDLILHADVRWLSRGKVLQRFINLLPEIISFLKSRKEEYRELADDTWLLDLAFLTDLTSKLNELNCELQGKDCDVPHMVSAVNAFKVKLALWTSQLKCKKLTHFQNVDKMLNNISNKDSFHPENFCIHLNRLEEEFSKRFEELN--KDIIEELSAKFQQV-FELPNGV------------DMEIIDLENDIEM--KARSRDKDFWGLVSRERYPSLSACALKVKAFFGSTYFCEMSF 548 HSP 2 Score: 113.235 bits (282), Expect = 5.013e-84 Identity = 53/115 (46.09%), Postives = 77/115 (66.96%), Query Frame = 2
Query: 1760 RSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
R + ++ D Q+ ++L C YFS+Q DES+D+ D AQL +FVRM F+ V+E+ L +L L T G+DIY+ + + EN++ KLVSIT DGAPA+ G+H FIALC+K+
Sbjct: 154 RRVELLSEDISKQVLSDLSRCEYFSLQFDESVDITDTAQLVVFVRMTFSDASVKEDFLTLLPLNERTRGEDIYRAFRTYATENDLPFQKLVSITRDGAPAMCGIHAGFIALCRKD 268 HSP 3 Score: 35.4242 bits (80), Expect = 5.013e-84 Identity = 19/38 (50.00%), Postives = 27/38 (71.05%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
CE F MK +K+ Y T LT+ +L +C+RLAV+NY+P
Sbjct: 543 FCEMSFPQMKIIKSKYRTCLTDAHLTDCVRLAVSNYTP 580 HSP 4 Score: 24.2534 bits (51), Expect = 5.013e-84 Identity = 10/15 (66.67%), Postives = 11/15 (73.33%), Query Frame = 3
Query: 1680 KKTFEDGEYLKQAFL 1724
KKTF DGE K+A L
Sbjct: 108 KKTFTDGELFKEAML 122
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000030525.1 (pep primary_assembly:Astyanax_mexicanus-2.0:1:12992682:12994541:1 gene:ENSAMXG00000035573.1 transcript:ENSAMXT00000030525.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 167.548 bits (423), Expect = 5.116e-59 Identity = 109/300 (36.33%), Postives = 161/300 (53.67%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQE---LSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSK-----NQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI*N 2984
E I+ HCIIHQQALC+K L ++VM +VVK IN IR ++L+ R F+ + + ++ +YG++L EVRWLS+G IL+RF EL ++ F+E LS+ WL DLAFL DIT +LN LN LQ + + V + ++ F KL+L K L + + HFP K + ++ TPFS E Y+ + L EEF+ RF DF + + PF + +++ V L+MELI + EL +F + ++L P +P L + + CL GST F N
Sbjct: 322 EAIALHCIIHQQALCSKCLKFDNVMSVVVKCINQIRSRSLKHRRFRALLEEMESEYGDVLYFTEVRWLSRGNILKRFFELRAEVKAFMEKDGVAVTVLSDPKWLMDLAFLVDITHELNVLNKKLQGQGQLVSAAYDNVRAFSAKLMLWKAQLSQTNFCHFPACK-ALMDAGTPFSGEKYVDAILMLQEEFDHRFADFKTHRATFQIFADPF-SFDVQDAPPV-----------LQMELIDLQCNSELRAKFREVSGKADKLGQFLRELPLSFPELSRMFKRTMCLFGSTYLCEKLFSTLN 608 HSP 2 Score: 82.0333 bits (201), Expect = 5.116e-59 Identity = 60/176 (34.09%), Postives = 90/176 (51.14%), Query Frame = 2
Query: 1595 QQTFFKKQAGKNEVATLASFRVCKVLT-----------IKKNI*RW*IFKTSILRSWQL*LHCNYQRSEDSMA-------SDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTG 2068
QQ FFKK +N+ A AS+ V +++ +KK I + SI+ + N S +++A SD + QL +S+ LDES D+ D AQLAI+VR V + F+V EELL ++ + G T Q+I+ + D I + + V ITTDGAP++TG
Sbjct: 139 QQDFFKKATKENDAAVEASYVVSEMIAKAGKPFTEGEFVKKCI----LQAASIVCPEKKGQFSNISLSANTVAERISDLSSDIYDQLCEKAKRFSVYSVALDESTDITDTAQLAIYVRGVDDNFEVTEELLTVIPMHGQTTAQEIFHQLCDAIENAGLPWKRFVGITTDGAPSMTG 310
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000052542.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000549.1:35642:40620:1 gene:ENSAMXG00000033785.1 transcript:ENSAMXT00000052542.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 148.288 bits (373), Expect = 9.048e-54 Identity = 81/222 (36.49%), Postives = 124/222 (55.86%), Query Frame = 3
Query: 2115 PEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQE---LSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSG 2771
E YHCIIHQ+ALC K L +M VV +N IR ++L R F+ + + YG+++ H EVRWLS+G +L+ F L +I LFLE + ++ + N W+ DLAFLTD+T LN+LN+ LQ KD+ + + A+ F KL L L + +L HFP +E + + +S S ++ L F RF F + ++ + PF +++ ET+ G
Sbjct: 274 AELKHYHCIIHQEALCGKHLQFKQIMDFVVSAVNFIRARSLNHREFQSFLEDISAAYGDVIYHTEVRWLSRGNVLKIFFALRNEIKLFLEQKGKDTLVMENTDWIADLAFLTDLTGLLNELNLKLQGKDRLICHLFEAVCAFEMKLNLFATQLKKGNLTHFPTCQEAFAHKNYNWSRHSC--VLEDLKLAFSARFGQFRNEQATLQLLADPF-SVDTETVPG 492 HSP 2 Score: 83.5741 bits (205), Expect = 9.048e-54 Identity = 62/205 (30.24%), Postives = 98/205 (47.80%), Query Frame = 2
Query: 1577 EKSLNYQQTFFKKQAGKNEVATLASFRV------------------------CKVLTIK-----KNI*RW*IFKTSILRSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
+K L QQ F+K+ ++E T+AS+R+ C V+ + KNI S+ R+ QR ++S+++ QL++ ++ YFS LDES D D AQL+IF+R V T V +EL ++ L G T G +I+ K + N+ KL ++TTDGAP++ G FI K++
Sbjct: 78 KKQLVSQQGVFEKRRKESEACTIASYRIANLVAKSARPFIDGEFVKDCMLEACDVICPEAKDAFKNI--------SLSRT-------TIQRRIVDLSSNSYCQLQSRINDVTYFSAALDESTDNTDTAQLSIFIRGVTGTCQVYQELAALVPLYGRTTGFEIFNAFKTAVENLNLPWSKLSAVTTDGAPSMVGETNGFIGHLKRH 267
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000037725.1 (pep primary_assembly:Astyanax_mexicanus-2.0:14:29162452:29166863:1 gene:ENSAMXG00000037303.1 transcript:ENSAMXT00000037725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 153.295 bits (386), Expect = 1.823e-53 Identity = 97/295 (32.88%), Postives = 154/295 (52.20%), Query Frame = 3
Query: 2115 PEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQE---LSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQ----LEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
E YHCIIHQ+ALC K L+ +M VV +N IR ++L+ R F + + YG+++ H EVRWLS+G +L+RF L +I LFLE + ++ + N W+ DLAFLTD+T LN+LN+ LQ KD+ + + A+ F KL L L + +L HFP +E + + +S S ++ L F RF F + ++ + PF +++ ET+ G +L+ E+I++ + +K++ LEF + +P L A K + GST F +
Sbjct: 462 AELKHYHCIIHQEALCGKHLHFKEIMDFVVSAVNFIRARSLKHREFPSFLEDISAAYGDVIYHTEVRWLSRGNVLKRFFALRNEIKLFLEQKGKDTLVMENTDWIADLAFLTDLTGLLNELNLKLQGKDRLICHLFEAVCAFEMKLNLFATQLKKGNLTHFPTCQEAFAHKNYNWSRHSC--VLEDLKLAFSARFGQFRNEQATLQLLADPF-SVDTETVPG-----------ELQPEIIELKCSTAMRTKHREMPLLEFYQSLDREQFPNLFANAQKWISMFGSTYICEQMFSL 742 HSP 2 Score: 77.7962 bits (190), Expect = 1.823e-53 Identity = 41/110 (37.27%), Postives = 65/110 (59.09%), Query Frame = 2
Query: 1775 MASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
++S+++ QL++ ++ YFS LDES D D AQL+IF+R V T V +EL ++ L G T G +I+ K + N+ KL ++TTDGA ++ G FI K++
Sbjct: 346 LSSNSYCQLQSRINDVTYFSAALDESTDNTDTAQLSIFIRGVTGTCQVYQELAALVPLYGRTTGFEIFNAFKTAVENLNLPWSKLSAVTTDGALSVVGETNGFIGHLKRH 455
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000035253.1 (general transcription factor II-I repeat domain-containing protein 2B-like [Source:NCBI gene;Acc:111191579]) HSP 1 Score: 143.665 bits (361), Expect = 8.388e-52 Identity = 98/311 (31.51%), Postives = 150/311 (48.23%), Query Frame = 3
Query: 2073 IKILLHYVKKIKNYPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRH---QELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIELS*EFSKNQ----LEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI*N 2984
+ ++ ++K+ + I+YHCIIHQ+ALC K L M++++ V+K +N IR + L R F+ +D ++G++L H EVRWLS+ RF EL I+LF++ + ELS+ WL D A L DIT L LN LQ + + + M + + F +KL L +++L HFP + FSC +S L EF++RF DF + PF + L+MELI++ S +K Q +F + P P LR A ++ + GST F I N
Sbjct: 259 VGLMKGKMQKMNCHMPLITYHCIIHQEALCGKVLGMDNIVTTVMKTVNFIRARGLNHRQFQMFLQEIDSEHGDVLYHTEVRWLSRS----RFFELREDIALFMQSKGNPLSELSDPKWLCDFAVLCDITEHLAQLNQKLQGRKQVITQMSDMITAFQRKLDLWMCQAKQDNLAHFPVCQSMSALFPGTFSCAQLTTKLSRLKTEFDRRFSDFRGQQSGFAIFANPF------------TTDVCTAPQHLQMELIELQSDSGLRAKFQDAAIQDFYRLLPPGLMPQLRLHAARVLSMFGSTYLCEQMFSIMN 553 HSP 2 Score: 81.6481 bits (200), Expect = 8.388e-52 Identity = 63/186 (33.87%), Postives = 89/186 (47.85%), Query Frame = 2
Query: 1586 LNYQQTFFKKQAGKNEVATLASFRVCKVLTIKKNI*RW*IF-KTSILRSW------QL*LHCNYQRSEDSMASDTFVQLKNNLDTCFY--------FSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCK 2098
L QQ F K KN A ASF V + + F K +L+ Q+ N S +++A D +L NL T FS+ +DES D D AQLAIF+R V + V E+LL + + G T GQDI+ V+ +++N + + LV +TTDGAPA+ G + L K
Sbjct: 79 LKSQQNLFTKATAKNSAAVKASFIVAEEIARASKYFSGGAFLKQCMLKVCEQVCPDQIQTFKNVSLSRNTIA-DRVKELAENLATQLAEETRSYTAFSLAVDESTDNTDTAQLAIFIRGVKSDLSVTEDLLDVAAMHGTTTGQDIFDAVEKSVSKNALAWENLVGLTTDGAPAMCGEKNGLVGLMK 263
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Medaka
Match: ENSORLT00000033470.1 (pep primary_assembly:ASM223467v1:22:24335229:24337076:1 gene:ENSORLG00000028972.1 transcript:ENSORLT00000033470.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 216.468 bits (550), Expect = 1.927e-87 Identity = 116/306 (37.91%), Postives = 183/306 (59.80%), Query Frame = 3
Query: 2091 YVKKIKN---YPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQELS---NVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSC-----ESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMI-ELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
++ + KN +P+F+ YHCIIHQQA+CAK + VM VVKIINSIR KA Q R+FK + D L +YG+LLLH E+RWLS+G+IL+RF LL +I F++ + ++ S + W+ DLAFLTD+T LN LN +LQ KDK V I+A+ F KL + L + + HFP+++ +N++ + + + Y +++ L +EFE RF DF +++P V F+ PF+ +++ + + +S F + +EME++ + +L + ++ F V Y + A+KI+C GST F
Sbjct: 263 FIAQCKNDPDFPKFLHYHCIIHQQAICAKVTGFDHVMTPVVKIINSIRSKAKQHRMFKMLMDELSAEYGDLLLHTEIRWLSRGRILQRFLSLLGEIKEFMKSKGEDTSLLEDPEWVLDLAFLTDLTGNLNHLNRELQGKDKTVAHTISAVNAFRAKLSIFSTQLQKKKMLHFPSVQAALNDNVSASAALNEAVKKYSQVINRLGQEFEDRFCDFEQLEPCVSFVTNPFMQVDVTSTAEQLSALFTLNAGDVEMEILTLQNDLLLKAHQSAPNFWCLVDQEKYSGVCTAAMKIACFFGSTYLCESAF 568 HSP 2 Score: 107.457 bits (267), Expect = 1.927e-87 Identity = 80/203 (39.41%), Postives = 106/203 (52.22%), Query Frame = 2
Query: 1553 QKEEG*GSEKSLNYQQTFFKKQAGKNEVATLASFRVCKVLTIKKN-------------I*RW*IFK--------TSILRSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCK 2098
+ E+ G + +L+ Q+TFF + A K+ AT ASFR L K + IFK S L QL R S++ + +L +L C +FS+Q DES+D AQL IF+RMVF F +EELL +L L+ T G DIY VK+F E + + KLVS+TTDGAPA+TG H FIA CK
Sbjct: 67 RTEKARGLKAALDMQRTFFTRPAKKSHNATEASFRAAHFLIKNKKPFSDGEVLKEAMMLVANTIFKDEKYAPDVISTLSDVQL-GASTIARRVTSLSENLTEKLDRDLAACRWFSVQCDESVDSASTAQLMIFIRMVFEDFSTKEELLTLLPLKTTTRGVDIYTTVKNFFVEKKVPVQKLVSVTTDGAPAMTGRHVGFIAQCK 268 HSP 3 Score: 42.3578 bits (98), Expect = 1.927e-87 Identity = 23/38 (60.53%), Postives = 30/38 (78.95%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
LCES FSNM F+KN + T LT+ +L + LR+AV+NYSP
Sbjct: 563 LCESAFSNMNFIKNKHRTCLTDAHLQDSLRIAVSNYSP 600 HSP 4 Score: 59.6918 bits (143), Expect = 1.244e-8 Identity = 46/131 (35.11%), Postives = 67/131 (51.15%), Query Frame = 3
Query: 1380 MAKKRKN-YHFHE----EFF-IYVND--ICIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVEDXXXXXXXXXXXXXXXXXXXXXXX*HPFASAKF*LL-KKTFEDGEYLKQAFLEVGSYSF 1745
M +KRK YHF + EFF ND +C+IC +++A+ R N+ERHF T H+N + +P S +R +K LK + + K F +A F + KK F DGE LK+A + V + F
Sbjct: 1 MTEKRKRVYHFQDDWEVEFFSTSFNDKCLCLICGTAIAVPMRHNVERHFKTCHKNFDANYPPGSALRTEKARGLKAALDMQRTFFTRPAKKSHNATEASFRAAHFLIKNKKPFSDGEVLKEAMMLVANTIF 131
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Medaka
Match: ENSORLT00000046355.1 (pep primary_assembly:ASM223467v1:21:4582475:4584322:1 gene:ENSORLG00000025904.1 transcript:ENSORLT00000046355.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 213.386 bits (542), Expect = 5.150e-83 Identity = 115/306 (37.58%), Postives = 179/306 (58.50%), Query Frame = 3
Query: 2082 LLHYVKKIKNYPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQELS---NVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFS-----CESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMI-ELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYF 2972
+ + K+ ++P+F+ YHCIIHQQALCAK + VM VVKIIN+IR KA Q R+FK + + + +YG+LLLH E+RWLS+G++L RF LL +I F++ + +++S + W DLAFL DIT KLN LN LQ K K V+ MI+A+ F K+ +L + HFP+++ + ++++ E Y+ +++ L +EFE RF D H+++P V FI PF+N + + +S F D Q+E+E+I + +L + + F V Y + A+K++ L GST F
Sbjct: 263 FIAHCKRDPDFPKFLHYHCIIHQQALCAKVIGFGHVMTPVVKIINNIRSKAKQHRIFKVLLEEMSAEYGDLLLHTEIRWLSRGRVLHRFLSLLREIKEFMQSKGEDVSLLEDTEWTLDLAFLVDITGKLNLLNCQLQGKGKTVVDMISALNAFKAKMNAFSADLQRKKVLHFPSVQSVLKDNASASETFEKVAEKYIEVINRLGQEFENRFCDLHQLEPCVFFISNPFMNGDTTCFAEQLSATFNLDAGQVEIEIITLQNDLHLKAYQAAPNFWRLVDTEKYSGVCTAAMKVASLFGSTYLCESAF 568 HSP 2 Score: 103.99 bits (258), Expect = 5.150e-83 Identity = 74/195 (37.95%), Postives = 104/195 (53.33%), Query Frame = 2
Query: 1583 SLNYQQTFFKKQAGKNEVATLASFRVCKVLTIKKN-------------I*RW*IFK--------TSILRSWQL*LHCNYQRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
+L QQ+FF + ++ A+ ASFR L KK + +FK S L QL R +M+S+ QL+ +L C +FS+Q DES+D AQL +F+RMVFN F +EELL +L L+ T G DIY VK+F + + L+KLV++TTDGAPA+ G FIA CK++
Sbjct: 77 ALGKQQSFFTRPTKNSQKASEASFRATHFLIKKKKAFTDGEVVKEAMLLIANTVFKDEKNGSDLISTLSDVQL-GASTMARRVSAMSSNLVDQLEQDLAKCKWFSLQCDESVDSSSTAQLLVFIRMVFNDFSTKEELLTLLPLKTTTRGVDIYNTVKEFFVQKKVPLEKLVAVTTDGAPAMVGRQTGFIAHCKRD 270 HSP 3 Score: 33.8834 bits (76), Expect = 5.150e-83 Identity = 19/38 (50.00%), Postives = 30/38 (78.95%), Query Frame = 2
Query: 2954 LCESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
LCES FS+M F+KN + T+LT+ +L + L +AV++Y+P
Sbjct: 563 LCESAFSDMNFIKNKHRTRLTDAHLRDSLTVAVSSYTP 600 HSP 4 Score: 64.6994 bits (156), Expect = 3.449e-10 Identity = 45/131 (34.35%), Postives = 68/131 (51.91%), Query Frame = 3
Query: 1380 MAKKRK-NYHFHEE-----FFIYVND--ICIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVEDXXXXXXXXXXXXXXXXXXXXXXX*HPFASAKF*L-LKKTFEDGEYLKQAFLEVGSYSF 1745
MA+KRK Y FH E FF V + +C+IC ++VA KR N+ERHFNT H++ + ++P S +R +K +LK + + F + F + KK F DGE +K+A L + + F
Sbjct: 1 MAEKRKKTYLFHSEWEEEFFFTTVKETCVCLICGTTVATAKRHNVERHFNTCHKSYHDKYPPASALRAEKARELKTALGKQQSFFTRPTKNSQKASEASFRATHFLIKKKKAFTDGEVVKEAMLLIANTVF 131
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Medaka
Match: ENSORLT00000027093.1 (general transcription factor II-I repeat domain-containing protein 2B-like [Source:NCBI gene;Acc:111947639]) HSP 1 Score: 142.124 bits (357), Expect = 5.175e-56 Identity = 97/289 (33.56%), Postives = 150/289 (51.90%), Query Frame = 3
Query: 2133 HCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLF-LEGRHQ--ELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EF-SKNQLEFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI 2978
HCIIHQ+ LC L M V+ +V K +N IR +AL R F + + ++G++ H VRWLS GK+L+ +L +I F ++ H ELS+ W+ DL F D+TA +N LNV LQ K V M +A++ F +KL L + +N+L H P LKE + Y ++ +L EF +RF DF ++ + + PF I + ++++MELI++ + L+ F S + L+F S + ++P LR A KI L GST + F +
Sbjct: 264 HCIIHQEVLCKTVLKMKHVVDVVTKTVNFIRARALNHRQFVAFLEENEIEHGDIRYHCTVRWLSLGKVLKSVWDLRGQIQDFCVDKGHDVPELSDEDWVADLGFAVDVTALMNQLNVKLQSKGLFVHEMYSAVKAFMRKLQFLSSQVKDNNLTHLPTLKEAKRPEG---HLQKYSTMLEALHAEFSRRFQDFKTLESEMHVVSSPFNCI------------VDDAPSEVQMELIELQSDMLLAERFRSVSLLDFYSSLKKENFPHLRRHAQKILVLFGSTYHCEQAFSV 537 HSP 2 Score: 73.9442 bits (180), Expect = 5.175e-56 Identity = 43/104 (41.35%), Postives = 64/104 (61.54%), Query Frame = 2
Query: 1757 QRSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTG 2068
+R ED +A + +QLK+ FS+ LDES D+ D AQL IF+R + F + EEL + +++G T GQD+++ V ++ + DKLV +TTDG P LTG
Sbjct: 138 RRIED-IAGNLELQLKSRAADFDCFSLALDESCDIRDTAQLLIFLRGITAEFQITEELAAMRSMKGTTTGQDLFREVNACLDMLELKWDKLVGVTTDGCPNLTG 240 HSP 3 Score: 40.0466 bits (92), Expect = 5.175e-56 Identity = 36/106 (33.96%), Postives = 51/106 (48.11%), Query Frame = 3
Query: 1419 FFIYVND--ICIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVEDXXXXXXXXXXXXXXXXXXXXXXX*HPFA-SAKF*LLKKTFEDGEYLKQAFLE 1727
FF V +C+IC + VA++K NL RH+ TKHE E R L+ E R K+ E L + + A + F S K K F DGE++K+ L+
Sbjct: 10 FFTEVKGEAVCLICGAKVAVFKDYNLNRHYTTKHE-EKYR-NLSDEERAKESEALLQKLQTQQGLLTKLHAPRNAAVRTSFVISHKIARNSKPFSDGEFVKECLLD 113 HSP 4 Score: 25.0238 bits (53), Expect = 5.175e-56 Identity = 14/37 (37.84%), Postives = 23/37 (62.16%), Query Frame = 2
Query: 2957 CESVFSNMKFMKN*YXXXXXXXXXDNCLRLAVTNYSP 3067
CE FS MKF K+ + + +T+ +L LR+A ++ P
Sbjct: 531 CEQAFSVMKFNKSKHRSSVTDDHLSAVLRIATSDIQP 567
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Medaka
Match: ENSORLT00000044825.1 (general transcription factor II-I repeat domain-containing protein 2-like [Source:NCBI gene;Acc:111949247]) HSP 1 Score: 162.54 bits (410), Expect = 1.317e-55 Identity = 109/303 (35.97%), Postives = 165/303 (54.46%), Query Frame = 3
Query: 2130 YHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQEL---SNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKE-EVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQL-EFCSHVTPNHYPFLRDVALKISCLIGSTTYVNPYFQI*NS*RINIEQNL 3014
YHCI+HQ+ LCAK + + V++ VVKIIN IR KAL R F+ D +D QY ++L H EVRWLS+G +L+RF EL I+ FL ++ ++ W+ D+AF+ DIT LN+LNV LQ K++ + + + ++ F KL LL +L + HFP+L++ V P Y ++S+L +EF RFVDF K ++ PF +++ +++ L+MELI+ EL +F L +F HV+ YP +R A + L GST F + N +I + L
Sbjct: 242 YHCILHQEQLCAKTIGLADVVRDVVKIINCIRSKALSHRQFRAFLDEVDAQYKDILYHQEVRWLSRGTVLKRFFELRQLIAEFLSSASRDTQIPTDKRWIFDVAFMVDITDLLNNLNVKLQGKEQIITELFDHIKAFQMKLQLLCRHLSAGNFAHFPSLRDVNVEVDRLP----EYGELLSNLNKEFNLRFVDFKKTAGDMELFSQPF-SVSPDSVP-----------EHLQMELIEFQCDTELRRKFVSLPLRDFYPHVSKQRYPQMRKNAQVMLSLFGSTYICEQTFSLMNLNKIKLRGTL 528 HSP 2 Score: 75.485 bits (184), Expect = 1.317e-55 Identity = 37/88 (42.05%), Postives = 54/88 (61.36%), Query Frame = 2
Query: 1829 FSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIAL 2092
FS+ DES D+ D AQL +FVR + ++ +EL + TL G T G+D++ V +++ N+ DK+V ITTDGAPA+ G AL
Sbjct: 140 FSLACDESTDISDSAQLLVFVRGINADMEITQELAGLETLRGTTKGEDLFAAVSRVLDKYNLSWDKMVGITTDGAPAMIGKKAGLTAL 227
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Medaka
Match: ENSORLT00000033718.1 (general transcription factor II-I repeat domain-containing protein 2 [Source:NCBI gene;Acc:110015985]) HSP 1 Score: 144.436 bits (363), Expect = 4.968e-53 Identity = 82/244 (33.61%), Postives = 129/244 (52.87%), Query Frame = 3
Query: 2118 EFISYHCIIHQQALCAKFL--NMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRH---QELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFV----NINIETLSGVISNQFGNDKAQLEMEL 2822
+ +++HCI+HQ+ALCA+ VM LV++I+N I L R F+ + D LD Y +LLLH +VRWLS+G +L+RF L ++ +FL + EL W L F+ D+TA LN LN LQ K + M+ + F +KL + +L L HFP L+ E + + + +++++ F KRF +F + K + F + P +N+ +GV+S + LEMEL
Sbjct: 276 KLLTFHCILHQEALCAQTFPPECTQVMDLVIQIVNKIMANGLNHRQFRSLLDELDSAYSDLLLHNKVRWLSRGVVLKRFAACLEEVKVFLSNKGLTFPELEQPEWQEKLHFMVDMTAHLNTLNTSLQGKGGTALHMLEEVLGFERKLTVFATDLKRGTLYHFPALR-EFQQAGNAINSQYLKSVITAMQTSFGKRFCEFRQEKHTLSFPVTPLTIDPSQLNMTAFAGVVS------QPDLEMEL 512 HSP 2 Score: 62.3882 bits (150), Expect = 4.968e-53 Identity = 34/111 (30.63%), Postives = 64/111 (57.66%), Query Frame = 2
Query: 1772 SMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKN 2104
+MA + Q ++++ +++ + S D D Q+A+F R V + +EE+++++ L+G T G+DI + V + I LV + +DGAP++TG K F+AL +K+
Sbjct: 163 NMAENVTRQQIEDINSALAYAIACNMSKDKNDIEQIALFCRYV-SAAGPQEEMIELIPLKGQTRGEDICEAVLHCLRTKEIKTTHLVPVASDGAPSMTGAQKGFVALLQKS 272 HSP 3 Score: 43.5134 bits (101), Expect = 4.968e-53 Identity = 32/105 (30.48%), Postives = 54/105 (51.43%), Query Frame = 3
Query: 1440 ICIICYSSVAMYKRENLERHFNTKHENENTRFPLNSEIRKKKVEDXXXXXXXXXXXXXXXXXXXXXXX*HPFASAKF*LLK--KTFEDGEYLKQAFLEVGSYSFT 1748
+C+IC +A K+ N+ RHF KH ++P E RKK V +L + +++ K + F A+ ++K K F DGEYLK+ F+++ + F+
Sbjct: 33 VCLICGEILANDKKSNVARHFENKHSAFAKKYPKGEE-RKKAVSELMQKADVSRSHFKKWIKTGNSTTCTSFVVAQE-IVKHGKPFTDGEYLKETFIKISKHLFS 135
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Planmine SMEST
Match: SMESG000062458.1 (SMESG000062458.1) HSP 1 Score: 429.869 bits (1104), Expect = 4.923e-144 Identity = 224/224 (100.00%), Postives = 224/224 (100.00%), Query Frame = 2
Query: 68 MGWELKRREVKSIFPLDGCLCFDNRMGCFIGALTTAFTSAFSLILIILDVSEWLDRSFKISGGFPADWRQTFWKGFVLCDIAMLIAHPXXXXXXXXXXXXXXXPAKCKIYDLHPQVRSWCIIMFCYIITELGVSFYIFSWYGLAAWRRPYLIFLIMFYILRSISNVAFLIVGYSYKCEIYQELKTPTDAVDNEFDYMSRVTSHKAPSQIFSGSYISPIGSNQVV 739
MGWELKRREVKSIFPLDGCLCFDNRMGCFIGALTTAFTSAFSLILIILDVSEWLDRSFKISGGFPADWRQTFWKGFVLCDIAMLIAHPIMLVISLILSVSILSPAKCKIYDLHPQVRSWCIIMFCYIITELGVSFYIFSWYGLAAWRRPYLIFLIMFYILRSISNVAFLIVGYSYKCEIYQELKTPTDAVDNEFDYMSRVTSHKAPSQIFSGSYISPIGSNQVV
Sbjct: 1 MGWELKRREVKSIFPLDGCLCFDNRMGCFIGALTTAFTSAFSLILIILDVSEWLDRSFKISGGFPADWRQTFWKGFVLCDIAMLIAHPIMLVISLILSVSILSPAKCKIYDLHPQVRSWCIIMFCYIITELGVSFYIFSWYGLAAWRRPYLIFLIMFYILRSISNVAFLIVGYSYKCEIYQELKTPTDAVDNEFDYMSRVTSHKAPSQIFSGSYISPIGSNQVV 224
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Planmine SMEST
Match: SMESG000037770.1 (SMESG000037770.1) HSP 1 Score: 84.3445 bits (207), Expect = 4.507e-42 Identity = 65/191 (34.03%), Postives = 97/191 (50.79%), Query Frame = 2
Query: 1580 KSLNYQQTFFKKQAGKNEVATLASFRVC-KVLTIKKNI*RW*IFKTSILRSWQL*LHCNYQRSE-------------DSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKKNKK 2110
+SL +QT F K + E AT AS + K++ K K +L + N ++ E +S+A D QL N + T +FS+ LDES D+ D AQL IF+R + + F EELL + L+ T GQD++ + +++ + LDKL S+TTDGAP+LTG + I K + K
Sbjct: 599 RSLKQEQTIFLKPSSIQEAATKASLVIAHKIVKHNKPFSEGEFVKDCVLEIADIICPENKKKFENISLSRRTVVRRIESIAEDLSDQLLNKIKTFQWFSIALDESTDIQDTAQLLIFIRGIDDKFIATEELLSMEHLKDTTTGQDLFDNLIKALDKFELPLDKLASVTTDGAPSLTGKNVGLITKIKDHVK 789 HSP 2 Score: 83.5741 bits (205), Expect = 4.507e-42 Identity = 57/166 (34.34%), Postives = 82/166 (49.40%), Query Frame = 3
Query: 2091 YVKKIKNYPEFISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRH------QELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIE 2570
+VK + I HCIIHQ++LC L+ N+++ L LQ FK + L+ + ++L H VRWLS GK+L+R L +I LFLE + ++ WL D +F DI KLN+LNV LQ K + ++ F KL L +L E
Sbjct: 787 HVKNLHPDHTIIPLHCIIHQESLCKSVLDFNTLLTL------------LQ---FKSFLEDLESDHSDVLYHTNVRWLSLGKVLKRVWNLKDEIVLFLEMKDITVEFTTQMKTSEWLSDFSFAVDILDKLNELNVKLQGKGVFAHELFAEVKSFQVKLQLFSRHLKE 937 HSP 3 Score: 45.0542 bits (105), Expect = 4.507e-42 Identity = 23/49 (46.94%), Postives = 32/49 (65.31%), Query Frame = 3
Query: 1425 IYVNDICIICYSSVAMYKRENLERHFNTKHENENTRFPLN---SEIRKK 1562
I N +C+IC SVA++K NL+RHF TKH N F +N +E+R+K
Sbjct: 549 IKTNAVCLICRESVAVFKEYNLKRHFQTKHGN----FGINLNETELRRK 593
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Planmine SMEST
Match: SMESG000045419.1 (SMESG000045419.1) HSP 1 Score: 95.9005 bits (237), Expect = 5.523e-33 Identity = 78/278 (28.06%), Postives = 127/278 (45.68%), Query Frame = 3
Query: 2130 YHCIIHQQALCAKFLN-MNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLFLEGRHQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNVMLMINAMQCFGQKLILLKMNLIENDLKHFPNLKEEVNNSSTPFSCESYLPIVSSLIEEFEKRFVDFHKVKPIVKFIMYPFVNINIETLSGVISNQFGNDKAQLEMELIKMIE---LS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGST 2951
+HCIIHQ++LC L+ M +M ++ +N IR L+ R FK +D ++ +++ + VRWLS+G +LRR L + + LAF+ DIT LN+LN++LQ K K + + + F KL LLK ++IE +L HF K S P + + + F+DFH ++ + PF N++I + +L+ME++++ L F ++ P Y L A K+ GST
Sbjct: 255 FHCIIHQESLCCTILSSMKDIMNTLISTVNYIRRHGLKHRQFKKFLKEIDSEFNDVIYYSAVRWLSRGAVLRRKYYL------------------TAIGSLAFMVDITTYLNELNLNLQGKGKLLADLFCDINAFEAKLCLLKKHMIEENLTHFICCK------SVP--ADGWQTQKGTF-------FMDFHNKSSEIRLFLNPF-NVDINDVPN-----------ELQMEILQLQHNEILKNAFLLENIQHFYRCLPKQYEGLISFAKKMIVAFGST 487 HSP 2 Score: 65.855 bits (159), Expect = 5.523e-33 Identity = 35/103 (33.98%), Postives = 59/103 (57.28%), Query Frame = 2
Query: 1760 RSEDSMASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTG 2068
R + + ++ F QLK + +S+ +DES+D+ D AQL IF+R + F+V EEL + +L+ G D++ VK+ +N + +KL +TTDG + G
Sbjct: 129 RRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELTSLCSLKDAITGNDLFIKVKETLNSLELRWEKLKCVTTDGGRNMCG 231
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Planmine SMEST
Match: SMESG000025120.1 (SMESG000025120.1) HSP 1 Score: 107.071 bits (266), Expect = 4.754e-32 Identity = 70/168 (41.67%), Postives = 97/168 (57.74%), Query Frame = 3
Query: 2121 FISYHCIIHQQALCAKFLNMNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKGKILRRFRELLPKISLF---LEGRHQELSNVSWLRDLAFLTDITAKLNDLNVDLQEKDKNV------MLMIN-AMQCFGQKLILLKMNLIENDLKHFPN 2594
F + I+HQ+ALC K L +K+V KIINSIR LQ RLFK + + + + +L+LH EV WLSKGKIL RF L+ +I F ++ + EL++ L DL FLTDI K + KDKN+ + ++N A++ F KL LL +L N L HFP+
Sbjct: 402 FQTLRPIMHQEALCCKILPFEHDIKIVTKIINSIRAAPLQHRLFKTLLEDTEDKEHDLILHTEVSWLSKGKILTRFVSLIEEIKTFINDIKENYDELADSHRLIDLRFLTDIMEKFEFFKFGVARKDKNIADKVIAIPILNIAVKSFKAKLDLLISHLHINSLVHFPH 569 HSP 2 Score: 51.6026 bits (122), Expect = 4.754e-32 Identity = 23/59 (38.98%), Postives = 36/59 (61.02%), Query Frame = 2
Query: 1925 ELLKILTLEGPTLGQDIYQIVKDFINENNICLDKLVSITTDGAPALTGMHKDFIALCKK 2101
++L+IL +G G+DIY + + N+ L KL +ITTDGAPA+ G KD + ++
Sbjct: 340 DMLQILPRKGQARGEDIYNTFRIYAKSINMPLHKLFAITTDGAPAMVGKKKDLLTSARR 398
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Planmine SMEST
Match: SMESG000031560.1 (SMESG000031560.1) HSP 1 Score: 120.168 bits (300), Expect = 5.110e-32 Identity = 63/77 (81.82%), Postives = 65/77 (84.42%), Query Frame = 3
Query: 2730 MYPFVNINIETLSGVISNQFGNDKAQLEMELIKM---IELS*EFSKNQLEFCSHVTPNHYPFLRDVALKISCLIGST 2951
M PFVNINIETLS VISNQFG DKAQLEMELI + IELS E+SKNQLEF SHVTPN YPFLRDVA KISCL GST
Sbjct: 1 MDPFVNINIETLSEVISNQFGYDKAQLEMELISIQNEIELSCEYSKNQLEFWSHVTPNQYPFLRDVASKISCLFGST 77 The following BLAST results are available for this feature:
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of General transcription factor II-I repeat domain-containing 2A-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031645 ID=SMED30031645|Name=General transcription factor II-I repeat domain-containing 2A-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3098bpback to top protein sequence of SMED30031645-orf-1 >SMED30031645-orf-1 ID=SMED30031645-orf-1|Name=SMED30031645-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=225bp MGWELKRREVKSIFPLDGCLCFDNRMGCFIGALTTAFTSAFSLILIILDVback to top protein sequence of SMED30031645-orf-2 >SMED30031645-orf-2 ID=SMED30031645-orf-2|Name=SMED30031645-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=115bp MASDTFVQLKNNLDTCFYFSMQLDESLDVVDKAQLAIFVRMVFNTFDVREback to top protein sequence of SMED30031645-orf-3 >SMED30031645-orf-3 ID=SMED30031645-orf-3|Name=SMED30031645-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=223bp MNSVMKLVVKIINSIRGKALQRRLFKGVTDVLDCQYGNLLLHIEVRWLSKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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