Dpy-19 like C-mannosyltransferase 3

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNN--SFAKYFQEKFVNPTFRVYRV 2157
            KIL   I     + I L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    ++  F+ L  +N TE    IN++ RMNI+QE+FL  LY+++    + + P+ FY+ ++  LQ + +++++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ I +      +R      LS++      ++ST LF L WQF QF++L+++ V+F L+  + +    A   Y   + SLL    +Q  N M+L S  ++  +S  I    +   +   SF  RL  L +     L L L L  +   IL    D HIF+FL  KFG+G++R+FD NLY C E FG +P   F    + + + ++I  + +    +I A  V +H+      L  S ++  V   G    G   L    PE AY+   +     L L   RM+YL+T +  +++S    +  +++ + K     S   Y P          K+  +          M +S   +++  +C   ++ +  +  EL +LREFYDPDTV+L++WI  +T     FAGSMQL+A VKL + R + NHPHYED +LR +T+ +YQ+YAK+  + V  +L+ +   Y+ILEDSIC       GC+L+D++D++NGH+ +    +  DL     PRFC EI+       N   +  YF   F N TF VY++
Sbjct:   43 KILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVL-PIQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNL-QPLSERLTLLAIFISTFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQK-NLKTGSFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKSDEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSIT---VIVAFVVAFHN------LSDSTNQQSV---GKMEKGTVDL---KPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFGLCSPEIWELLLK-----SVHLYNP----------KRICI----------MRYSVPILILLYLC---YKFWPGMMDELSELREFYDPDTVELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDSSLRERTRAVYQIYAKRAPEEVHALLRSFGTDYVILEDSICYERRHRRGCRLRDLLDIANGHMMDGPGENDPDLKPADHPRFCEEIK------RNLPPYVAYFTRVFQNKTFHVYKL 712          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNN--SFAKYFQEKFVNPTFRVYRV 2157
            KIL   I     + I L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    ++  F+ L  +N TE    IN++ RMNI+QE+FL  LY+++    + + P+ FY+ ++  LQ + +++++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ I +      +R      LS++      ++ST LF L WQF QF++L+++ V+F L+  + +    A   Y   + SLL    +Q  N M+L S  ++  +S  I    +   +   SF  RL  L +     L L L L  +   IL    D HIF+FL  KFG+G++R+FD NLY C E FG +P   F    + + + ++I  + +    +I A  V +H+      L  S ++  V   G    G   L    PE AY+   +     L L   RM+YL+T +  +++S    +  +++ + K     S   Y P          K+  +          M +S   +++  +C   ++ +  +  EL +LREFYDPDTV+L++WI  +T     FAGSMQL+A VKL + R + NHPHYED +LR +T+ +YQ+YAK+  + V  +L+ +   Y+ILEDSIC       GC+L+D++D++NGH+ +    +  DL     PRFC EI+       N   +  YF   F N TF VY++
Sbjct:   43 KILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVL-PIQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNL-QPLSERLTLLAIFISTFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQK-NLKTGSFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKSDEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSIT---VIVAFVVAFHN------LSDSTNQQSV---GKMEKGTVDL---KPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFGLCSPEIWELLLK-----SVHLYNP----------KRICI----------MRYSVPILILLYLC---YKFWPGMMDELSELREFYDPDTVELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDSSLRERTRAVYQIYAKRAPEEVHALLRSFGTDYVILEDSICYERRHRRGCRLRDLLDIANGHMMDGPGENDPDLKPADHPRFCEEIK------RNLPPYVAYFTRVFQNKTFHVYKL 712          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIP 2004
            KIL   I     + I L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    ++  F+ L  +N TE    IN++ RMNI+QE+FL  LY+++    + + P+ FY+ ++  LQ + +++++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ I +      +R      LS++      ++ST LF L WQF QF++L+++ V+F L+  + +    A   Y   + SLL    +Q  N M+L S  ++  +S  I    +   +   SF  RL  L +     L L L L  +   IL    D HIF+FL  KFG+G++R+FD NLY C E FG +P   F    + + + ++I  + +    +I A  V +H+      L  S ++  V   G    G   L    PE AY+   +     L L   RM+YL+T +  +++S    +  +++ + K     S   Y P          K+  +          M +S   +++  +C   ++ +  +  EL +LREFYDPDTV+L++WI  +T     FAGSMQL+A VKL + R + NHPHYED +LR +T+ +YQ+YAK+  + V  +L+ +   Y+ILEDSIC       GC+L+D++D++NGH P
Sbjct:   43 KILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVL-PIQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNL-QPLSERLTLLAIFISTFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQK-NLKTGSFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKSDEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSIT---VIVAFVVAFHN------LSDSTNQQSV---GKMEKGTVDL---KPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFGLCSPEIWELLLK-----SVHLYNP----------KRICI----------MRYSVPILILLYLC---YKFWPGMMDELSELREFYDPDTVELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDSSLRERTRAVYQIYAKRAPEEVHALLRSFGTDYVILEDSICYERRHRRGCRLRDLLDIANGHKP 665          

Query:   19 FISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHI--PERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            FI  +  +   + Y  Y+ +  E  FW+SN  ++E+ I+F+ +  +YYSYY++ +         Y L  NN T     IN + +M+++ E+    LY+  G   E I P+ FY+  V  LQ + ++++F+ S  ++ + L G+L+VA F +NR   +R+ Y +PLREN+ALP++   +      ++S   +   ++F   +   ST  F + W++  +++ L++  +F L+ F           Y   + SL     +Q  N  LL S  +  L+++L+L       +   SF  ++  + +       L + L  +    +   ++ H+ +FL VKFG+  ++NF +N   C E     P + F + L   +   F  YI + +   +S L V++           S+ E++    G         +   PE+ YH   +  +  L ++++ ++Y++ PY  + ++    +  ++  + K +                       L +    L++ ++  +   I+   + K   E F  + TEL +L+EFYDPDTV+L++WIK        FAGS QLM A+KL +   + + P Y D +L  + + +YQ+Y+K+ A+ + +IL  YK +Y+I+ED+IC  +    GC++KD++D++NGH+   E    +Y         RFC+E++    +  + +  YF   + N ++ VY++
Sbjct:   53 FIGCLAAVTSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQQMSLYPELIASILYQATGS-NEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL-NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPALLVS-PLLSLVAALMLAKCLQLNVKKGSFVAKIIKV-INFYLVCTLTITLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQ-APSQDFFLRLTQSSLLPF--YILVLIICFLSMLQVIFRRIN-----GKSLKETVTLEDGR--------IGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWL----------------------RLRTVHPILLALILSMAVPTIIGLSLWK---EFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEGDKLTYSKYG-----RFCHEVK----INYSPYVNYFTRVYWNRSYFVYKI 715          

Query:   85 ESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFY----------------ERISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTK--PSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSN 1992
            E++  +S++S +E+ ++FRTE GLYYSY++  ++    LN  +++  + LTEYP VIN + R N++ E+ L   Y+I  K                  E +SPIE          FYV  + +L  L ++  FI    ++ S LGG+++V  F  N    +RV++  PLRE+F+ PF  + +L    ++R+TK    +L    I  +F+M      L WQF QFV+L +   +FA+ +  ++     R   +  +ISL     +  GN MLL+S+  + L+    + + K P  +  + S    W+ +Q    L   ++L++L++ I    DD+HI   L  KF   S ++FD  LY C   F +M  E     L         V + + +A++   +S +W     +++ H   H+                  ++ EL YH     A   L +++ R++   TP+  + +S+  S         +++    F    P                               AIV A++  +S +   +++T+   + EF +    +LI WIK+ST P   FAG+M  MA+VKL + RPIVNHPHYED  LR +T+ +Y MY++K A+ V R L + KV+Y ILE+S C+ +S  GC + +I D+ +
Sbjct:   43 ENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFM------LPWQFAQFVLLTQIASLFAVYVVGYIDICKLRKIIYIHMISLALCFVLMFGNSMLLTSYYASSLVIIWGILAMK-PHFLKINVSELSLWV-IQGCFWLFGTVILKYLTSKIFGIADDAHIGNLLTSKF--FSYKDFDTLLYTCAAEFDFMEKET---PLRYTKTLLLPVVLVVFVAIVRKIISDMW-GVLAKQQTHVRKHQ-----------------FDHGELVYHALQLLAYTALGILIMRLKLFLTPHMCVMASLICS---------RQLFGWLFCKVHP------------------------------GAIVFAILAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPIVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLKVNYYILEESWCVRRSKPGCSMPEIWDVED 637          

Query:   16 SFISSVTLIVINLGYCFY--IYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYE---------------RISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSS-FTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWM---PIEKF----LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVY-DKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC 1941
            ++++SV +I + +GY  Y  +Y+  E++  +S+++D E+ +++RTE GLYYSYY+  I+    L     +  + +TE+ + IN +NR N++ E+ L FLY+    F +                + P+E          FY+  V ++     SSIF L + ++ S+ GG LSV  F  N    +RV +  PLRE+FA PF   H+     +I+  K S  S   +     +  LLF   WQF QF    +   IF     + +  + A+    + +IS L    +  GN M++++ +  ++L   +I+  Y +P + +  F  R  ++   +     + L L+   +  L   DD+HIF  L  KF   S  NF   LY C   F ++    IEK     LI L +++  +F+          +   ++LW ++EE            +G  G              E+ Y+        V+  ++ R++   TP+  I +++F +++++  D+I+K I                                       R + ++ +I  + +    +IR +L    E+ +PD   L  WI+H+T     FAG+M +MA VKL + RPIVNHPHYE   +R +T K+Y M++KK    V +I+K+  V+Y + +   C
Sbjct:   26 TWLASVVIIGLLVGYINYQHVYTLFENDKHFSHLADFEREMAYRTEMGLYYSYYKTIINAPSFLEGVQEITHDTVTEHGHEINTLNRFNLYPEVILAFLYRPFRAFAKSANWQIELCWQVNRGELRPVESCEGIGNPHYFYITGVFIVAGTVASSIFYLGVLVSDSIFGGFLSVLCFAFNHGEATRVQWTPPLRESFAFPFIIGHIAILTFVIKYKK-SGHSMILLLTSMAVPALLF---WQFTQFAFFTQICSIFLAFSLDLIPFSTAKTVIHSHIISFLIGFLLLFGNEMMITALYFPSILALGMII--YISPLLSNLKF--RPAYVLFLAIIFASITLGLKIGLSKGLGIEDDAHIFDILRSKFT--SFANFHTRLYTCSAEFDFIQYSTIEKLCGTLLIPLALISLVTFVFN-------FVKNTNLLWRNSEE------------IGENG--------------EILYNVVQLCCSTVMAFLIMRLKLFMTPHLCIVAALFANSKLLGGDRISKTI---------------------------------------RVSALVGVIAILFYRGIPNIRQQLNVKGEYSNPDQEMLFDWIQHNTKQDAVFAGTMPVMANVKLTTLRPIVNHPHYEHVGIRERTLKVYSMFSKKPIAEVHKIMKEMGVNYFVFQLMNC 621          

Query: 1660 DLREFYDP--------DTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK-SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLN 2082
            ++RE Y P        D   ++ WIK +T     FAG + ++  V L +KRPIVNH H E   +  +T+ +Y +Y+++ +  +     Q K+ Y+I+    C  +  + C L  I D  +     ++Y           P+FC+E+ + N
Sbjct:  699 NIREEYFPTRYSKSGDDLDSMLEWIKLNTERDAVFAGPVDIIGTVHLTTKRPIVNHAHLEMRQIAERTEHVYSVYSRQQSSDIYNQCAQLKIQYLIISLDECTNEVRDDCDLLAIWD--DKQPAYQKY-----------PQFCHELLHKN 835          

Query: 1660 DLREFYDP--------DTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK-SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLN 2082
            ++RE Y P        D   ++ WIK +T     FAG + ++  V L +KRPIVNH H E   +  +T+ +Y +Y+++ +  +     Q K+ Y+I+    C  +  + C L  I D  +     ++Y           P+FC+E+ + N
Sbjct:  584 NIREEYFPTRYSKSGDDLDSMLEWIKLNTERDAVFAGPVDIIGTVHLTTKRPIVNHAHLEMRQIAERTEHVYSVYSRQQSSDIYNQCAQLKIQYLIISLDECTNEVRDDCDLLAIWD--DKQPAYQKY-----------PQFCHELLHKN 720          

Query:   25 SSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK--SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVY 2151
             S+  + + L  C Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    I    Y L  +N TE    IN++ RMNI+QE+FL  LY+I+      + PI FY+ +V  LQT+ + ++FI S  ++ S L G LS   + LNR   +RV + + LREN+++PF+ + V      +R  K   + Q+ + ++ ++ST  FCL WQF QFV+L+++ +I+ L+  +F++       Y   + SLL    +Q  N M+L S  ++ ++S+L +  ++T   M   F  R+  L++ +   L L   + + +  +L    D HIF+F+  KFG G++R+FD +LY C E FG +P++ F  ++  ++ YP    Y+C    L I  L V               + S+ G G              P++AY+   +    +L     RM+YL+T +    ++     + V+            +Y +              ++   T    +L+ +S   +++A    + ++ +  +  E+ +LREFYDPDTV+L+ WI+  T     FAGSMQL+A +KL + R + NHPHYED  LR +T+++YQ+YA++ A+ V ++L      YI+LEDSIC  +  S GC+L+D++DL+NGHI +    +  DL     PRFC  I+         ++  F   F N TF VY
Sbjct:   50 GSIVGVSLGLLCCIYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLKAPTIQQGLYELTHDNTTESKRTINILQRMNIYQEVFLSILYRIL-PIQTYLEPIYFYIYTVFALQTVYVIALFITSWLLSDSWLAGALSGVWYILNRVDTTRVEFTISLRENWSIPFFALQVAAITCYLRP-KLKPIHQRVVLWLVFVSTFCFCLTWQFNQFVLLVQALIIYTLDCLDFLTAEQVVSLYLMQVSSLLLVWLLQFCNSMILGSLVLSFIVSALFIKHFQTGLKM-GGFVIRVGKLALHTLLVLALTFTINYSAKKVLQLKSDEHIFKFIKAKFGFGATRDFDASLYLCEEAFGLLPLDTFERLAGTVLLYP----YLCTLSVLFILLLLVA------------LSNLSLNGLGQASGEKEDRTFKMRPDVAYNLMHTVFFGLLAFSTMRMKYLWTGHMCTIAAFGVCGKEVWA-----------LYLR--------------VLHCNTKTAMRLIRYSVPIVILAF---LYYKFWPRLMEEISELREFYDPDTVELMEWIRLKTPKRAVFAGSMQLLAGIKLCTGRVLTNHPHYEDQALRERTRQVYQIYARQSAEEVHKVLGSVGTDYIVLEDSICYERRHSRGCRLRDLLDLANGHIMDGPGENDPDLIPASHPRFCEGIK----TDMPPYSTLFTRVFKNKTFNVY 710          

Query:   16 SFISSVTLIVINLGYCFY----IYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEI--------------FLGFLYKIVGKFY--ERISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSF-SGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSN----GHIP--------ERRYFSYFDLDDVH----IPRFCNEIR 2073
            +F+  +T++++ +   F+    +    E++  +S++S +EK ++FRTE GLYYSY++  I+    ++  Y++  + LTEYP VIN + R N++ E+              F GF  K+       E + P+E          FYV  V LL    +S  FI    ++ S LGG ++V  F  N    +RV++  PLRE+F+ PF  + +L    ++R+  PS    K       +S + F L WQF QFV+L +   +FA  +  ++S A  +    T ++SL     +  GN MLL+SF  + L+S  I G     + +  +F  G +TW++ Q    ++  ++L+F+ + I   +DD+HI   +  KF   S ++FD  +Y C   F ++  +  +  +  +  P  ++ +       I  + V   + ++E+       +S             HLL+    L YH     A  VL +++ R++   TP+  I S +  S R ++  I +K+                                        Q  V+ ++C ++ +   +++++   + EF +    +L+ WIK STSPT  FAG+M  MA+VKL + R IVNHPHYED  LR +T+ +Y MY++K A+ V R L + +  Y ILEDS C  +S  GC + +I D+ +    G +P         R +FS    ++++    +P+   ++R
Sbjct:   59 AFVRGITVLILAVVAGFFHWYHLSHLFENDRHFSHMSTLEKEMAFRTEMGLYYSYFKTIIEAPSFMDGLYMIMNDRLTEYPLVINTLKRFNLYPEVVLASWYRAYSSTMNFFGFPTKLCWTINRGEGLDPVESCEGLGDPAYFYVAFVFLLNGAMMSLFFIYGTYLSGSRLGGTVTVLCFFFNHGESTRVMWTPPLRESFSYPFLVLQMLLLTYILRTKNPS----KNTMMALGISNVFFMLPWQFAQFVLLTQVASLFASYILGYLSPAKMQSILVTHMVSLAVCFLLMFGNSMLLTSFYASSLVS--IWGVIALRDRLVGTFRPGLITWVT-QCFAWVVSTVILKFMLSVIFGASDDAHISSLIKSKFT--SYKDFDTMMYTCAAEFDFIEADTPIRYIKTMLLPINVLIVAFIAGRTIQDVIVFLRNEKQEKSEDDETEQS-------------HLLAK-GVLVYHSLQLVAFAVLAVLIMRLKLFLTPHMCIMSCLICS-RQLFGWIGEKL--------------------------------------KLQMTVVGILCIMAAQGVVNLQSQWSIIGEFSNYPQEELLEWIKDSTSPTAVFAGAMPTMASVKLSTGRAIVNHPHYEDAGLRARTKMVYAMYSRKPAEEVKRNLIKLQADYFILEDSWCTRRSKPGCSMPEIWDVEDAENAGKVPLCTLMSRDSRPHFSTVFHNNIYKVLRVPKTARDVR 730          

Query: 1027 KFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTS 1725
            KFG G++R+FD +LY C E FG +P++ F  ++  ++ YP    Y+C    L I  L V               + S+ G G              P++AY+   +    +L     RM+YL+T +    ++     + V+    +                         ++   T    +L+ +S   +++A    + ++ +  +  E+ +LREFYDPDTV+L+ WI    S
Sbjct:    2 KFGFGATRDFDASLYLCEEAFGLLPLDTFERLAGTVLLYP----YLCTLSVLFILLLLVA------------LSNLSLNGLGQASGEKEDRTFKMRPDVAYNLMHTVFFGLLAFSTMRMKYLWTGHMCTIAAFGVCGKEVWALYLR-------------------------VLHCNTKTAMRLIRYSVPIVILAF---LYYKFWPRLMEEISELREFYDPDTVELMEWISGMNS 191          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIF-QFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            IL   I ++  I + L   +Y+ +  E++ W+SNI DVE+ ISFRTE GLYYSYY++ +    I      L  +N TE    IN++ RMN++QE+ L  +Y+ +  F+  + P+ FY+ ++  LQTL +S+++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ + +     L+R    +AL ++    + ++ST +F + WQF QFV+LL++ V+FAL+  + +        Y   +  LL    +Q  N M+L S  ++ +I+ L     KT ++   S   ++ ++ ++S    L           +   N  + +  Q   + F + S R+FD +LY C E F  +P + F   S  ++ YP    Y+C+   L ++AL+  +++       +    +                +   P++AY+   +     L L   RM+YL+T +  +++S    +  V+  + K      F  Y                 + R N++       R  + IA+I  + F+    I  EL +LREFYDPDTVQL++WIK +T     FAGSMQL+A VKL + R + NHPHYED  LR +T+++YQ+YA +  + V  IL+ +   Y ILEDS        C+L+D++DL NGH+  R   +  DL     PRFC+EI+        S++KYF   F N TF VYR+
Sbjct:   41 ILSHIIGAMMAIALGLLTSYYVATLHENDLWFSNIKDVEREISFRTECGLYYSYYKQMLLAPSIKQGIIDLIYDNKTESMRTINILQRMNVYQEVVLATIYRYL-PFWNYLEPVYFYIYTLFGLQTLYVSALYINSWLLSRTWLSGLLTAIWYIFNRVDTTRVEFTIPLRENWALPFFAVQIAGITYLLRPNL-TALKERMALSVVFISTFIFSITWQFNQFVLLLQALVLFALDCSDMIPAIKVTKLYLIQVTCLLAVCVLQFNNTMILGSLVLSFVIAKLQSQCIKTFDLFTIS---QMVFIIIKSLFLFL-----------VCFPNVPAKLKPQTNRIDFILCSCRDFDASLYLCEEAFRQLPFDTFGRFSDTLLFYP----YLCVLFILTMAALATTFNNFSSSNPNNMEKEKK-------------KPIYVKPDVAYNLMHTILFGCLALSTMRMKYLWTSHMCVFASFGLCSIEVWGMLLK-----CFRLY----------------TAQRANIM-------RYFVSIAVIIYLLFKFSPRIMEELSELREFYDPDTVQLMNWIKLNTPKNAVFAGSMQLLAGVKLCTGRVLTNHPHYEDKTLRERTKQVYQIYANRSPEDVHSILRSFGTDYAILEDS--------CRLRDLLDLDNGHV--RITDNDPDLKPSPSPRFCDEIKRDLP----SYSKYFTRVFKNKTFHVYRL 684          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSNGCQLKDIIDLSNGH-------IPERRYFSYF---------DLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            IL   I ++  I + L   +Y+ +  E++ W+SNI DVE+ ISFRTE GLYYSYY++ +    I      L  +N TE    IN++ RMN++QE+ L  +Y+ +  F+  + P+ FY+ ++  LQTL +S+++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ + +     L+R    +AL ++    + ++ST +F + WQF QFV+LL++ V+FAL+  + +        Y   +  LL    +Q  N M+L S  ++ +I+++++   +     +   SG + +  MQ      L                     Q   + F + S R+FD +LY C E F  +P + F   S  ++ YP    Y+C+   L ++AL+  +++       +    +                +   P++AY+   +     L L   RM+YL+T +  +++S    +  V+  + K      F  Y                 + R N++       R  + IA+I  + F+    I  EL +LREFYDPDTVQL++WIK +T     FAGSMQL+A VKL + R + NHPHYED  LR +T+++YQ+YA +  + V  IL+ +   Y ILEDS        C+L+D++DL NGH       I +  + S           DL     PRFC+EI+        S++KYF   F N TF VYR+
Sbjct:   41 ILSHIIGAMMAIALGLLTSYYVATLHENDLWFSNIKDVEREISFRTECGLYYSYYKQMLLAPSIKQGIIDLIYDNKTESMRTINILQRMNVYQEVVLATIYRYL-PFWNYLEPVYFYIYTLFGLQTLYVSALYINSWLLSRTWLSGLLTAIWYIFNRVDTTRVEFTIPLRENWALPFFAVQIAGITYLLRPNL-TALKERMALSVVFISTFIFSITWQFNQFVLLLQALVLFALDCSDMIPAIKVTKLYLIQVTCLLAVCVLQFNNTMILGSLVLSFVIAAMLVRRLQVTISAYRLHSGSV-YCHMQPNVPAKLKP-------------------QTNRIDFILCSCRDFDASLYLCEEAFRQLPFDTFGRFSDTLLFYP----YLCVLFILTMAALATTFNNFSSSNPNNMEKEKK-------------KPIYVKPDVAYNLMHTILFGCLALSTMRMKYLWTSHMCVFASFGLCSIEVWGMLLK-----CFRLY----------------TAQRANIM-------RYFVSIAVIIYLLFKFSPRIMEELSELREFYDPDTVQLMNWIKLNTPKNAVFAGSMQLLAGVKLCTGRVLTNHPHYEDKTLRERTKQVYQIYANRSPEDVHSILRSFGTDYAILEDS--------CRLRDLLDLDNGHVRITGSKISDIVFLSQIMDGPGDNDPDLKPSPSPRFCDEIKRDLP----SYSKYFTRVFKNKTFHVYRL 695          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSNGCQLKDIIDLSNGH-------IPERRYFSYF---------DLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            IL   I ++  I + L   +Y+ +  E++ W+SNI DVE+ ISFRTE GLYYSYY++ +    I      L  +N TE    IN++ RMN++QE+ L  +Y+ +  F+  + P+ FY+ ++  LQTL +S+++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ + +     L+R    +AL ++    + ++ST +F + WQF QFV+LL++ V+FAL+  + +        Y   +  LL    +Q  N M+L S  ++ +I+++++   +  ++  +++   + +   +             +  +I+    +S I       F + S R+FD +LY C E F  +P + F   S  ++ YP    Y+C+   L ++AL+  +++       +    +                +   P++AY+   +     L L   RM+YL+T +  +++S    +  V+  + K      F  Y                 + R N++       R  + IA+I  + F+    I  EL +LREFYDPDTVQL++WIK +T     FAGSMQL+A VKL + R + NHPHYED  LR +T+++YQ+YA +  + V  IL+ +   Y ILEDS        C+L+D++DL NGH       I +  + S           DL     PRFC+EI+        S++KYF   F N TF VYR+
Sbjct:   41 ILSHIIGAMMAIALGLLTSYYVATLHENDLWFSNIKDVEREISFRTECGLYYSYYKQMLLAPSIKQGIIDLIYDNKTESMRTINILQRMNVYQEVVLATIYRYL-PFWNYLEPVYFYIYTLFGLQTLYVSALYINSWLLSRTWLSGLLTAIWYIFNRVDTTRVEFTIPLRENWALPFFAVQIAGITYLLRPNL-TALKERMALSVVFISTFIFSITWQFNQFVLLLQALVLFALDCSDMIPAIKVTKLYLIQVTCLLAVCVLQFNNTMILGSLVLSFVIAAMLV---RRLQVTSTTYRIHINYARYRHA---------LVVFCYIIENVCNSEI------DFILCSCRDFDASLYLCEEAFRQLPFDTFGRFSDTLLFYP----YLCVLFILTMAALATTFNNFSSSNPNNMEKEKK-------------KPIYVKPDVAYNLMHTILFGCLALSTMRMKYLWTSHMCVFASFGLCSIEVWGMLLK-----CFRLY----------------TAQRANIM-------RYFVSIAVIIYLLFKFSPRIMEELSELREFYDPDTVQLMNWIKLNTPKNAVFAGSMQLLAGVKLCTGRVLTNHPHYEDKTLRERTKQVYQIYANRSPEDVHSILRSFGTDYAILEDS--------CRLRDLLDLDNGHVRITGSKISDIVFLSQIMDGPGDNDPDLKPSPSPRFCDEIKRDLP----SYSKYFTRVFKNKTFHVYRL 697          

Query:   19 FISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISF--EAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHI----PRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            F+  +  ++  + Y  Y+ +  E  FW+SN  D+E+ I+F+    +YYS+Y++ +           L  NN T     IN + +M ++ E+    LY++ G     + P+ FY+  +  LQ + +S++F+ S  ++ + L G+L+VA F +NR   +R+ + +PLREN+ALP++   V      +++   S+  ++        ST  F + W++  +++ L++  +  L+    V        +   + S+L     Q  N  +L+S  ++++I S+I  S +   M   +F  ++  +        +   +   + T ++  ND+ H+ +FL V+FG+  S+NF VN   C E     P + +L+ L   +   F +     L L I   SV            P   ++ V  G          +   PE+ YH   +  +  L ++ + M+YL+TPY  + ++    +  ++  + K I                           R   +  +M     +  + ++   S   E    I  EL++L E Y+ DTV+L++WI+        FAGS  +M  ++L +   + + P Y D +L  + + LYQ+Y+ + A+ + +IL  YK SY+++EDSIC  +    GC++KD++D++N H+         +  DV+      RFC+EI+   S     +  YF   F N ++ V+++
Sbjct:   53 FVGCMGAVISGMMYAIYLSTYHERKFWFSNRRDIEREITFQGSGAVYYSFYKDMLRAPSFERGVIELAYNNRTVPLKTINAVQQMTLYPELIASALYQMSGS-QGVVEPVYFYIGILFGLQGIYVSALFVTSWIMSGTWLAGMLTVAWFIINRTDTTRIEHSIPLRENWALPYFACQVAALTGFLKNNISSS-GERLCYLFMSASTYSFIMMWEYSHYLLFLQALALCLLDGLSLVPKEKVHEVHKMYIFSVLVAYLFQFENYAILTSPLLSLVIGSMIAKSLQI-SMKKGTFRAKVMKIMYFYLAFTIAVSLHFLIRT-VVPPNDNKHLLRFLEVRFGLNMSKNFTVNWLLCQESLQ-PPSQDYLLRLTQSSLLPFYI-----LVLFICMCSVT-QAIIRRLRGAPVSTDNRVEEGR---------IGERPEVIYHVVQTILLGSLAMVFEGMKYLWTPYVCMLTAFGLCSPELWTTLFKWI---------------------------RLKSVQPVMLAFVLSAAVPMVIGFSLWREFLPRILAELEELEEHYESDTVELMNWIRTQAPINAVFAGSPAIMGVIRLCTGWMVTSLPVYNDEDLMRRNENLYQIYSMRSAEDIYKILTSYKASYVVIEDSICNEVGVMKGCRVKDLLDVANDHVIN-------EDGDVYAYSKYGRFCHEIKMNYS----PYVNYFTRVFWNRSYSVFKI 715          

Query:   19 FISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISF--EAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHI----PRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            F+  +  ++  + Y  Y+ +  E  FW+SN  D+E+ I+F+    +YYS+Y++ +            + + +   P  +                   I+   +  + P+ FY+  +  LQ + +S++F+ S  ++ + L G+L+VA F +NR   +R+ + +PLREN+ALP++   V      +++   S+  ++        ST  F + W++  +++ L++  +  L+    V        +   + S+L     Q  N  +L+S  ++++I S+I  S +               +SM+                 ++  ND+ H+ +FL V+FG+  S+NF VN   C E     P + +L+ L   +   F +     L L I   SV              + E  +G                PE+ YH   +  +  L ++ + M+YL+TPY  + ++    +  ++  + K I                           R   +  +M     +  + ++   S   E    I  EL++L E Y+ DTV+L++WI+        FAGS  +M  ++L +   + + P Y D +L  + + LYQ+Y+ + A+ + +IL  YK SY+++EDSIC  +    GC++KD++D++N H+            DV+      RFC+EI+   S     +  YF   F N ++ V+++
Sbjct:   11 FVGCMGAVISGMMYAIYLSTYHERKFWFSNRRDIEREITFQGSGAVYYSFYKDMLR----------CFTHKILPSPTSL-------------------ILSAAFGVVEPVYFYIGILFGLQGIYVSALFVTSWIMSGTWLAGMLTVAWFIINRTDTTRIEHSIPLRENWALPYFACQVAALTGFLKNNISSS-GERLCYLFMSASTYSFIMMWEYSHYLLFLQALALCLLDGLSLVPKEKVHEVHKMYIFSVLVAYLFQFENYAILTSPLLSLVIGSMIAKSLQ---------------ISMKKG---------------VVPPNDNKHLLRFLEVRFGLNMSKNFTVNWLLCQESLQ-PPSQDYLLRLTQSSLLPFYI-----LVLFICMCSVT-QAIIRRLRTDNRVEEGRIG--------------ERPEVIYHVVQTILLGSLAMVFEGMKYLWTPYVCMLTAFGLCSPELWTTLFKWI---------------------------RLKSVQPVMLAFVLSAAVPMVIGFSLWREFLPRILAELEELEEHYESDTVELMNWIRTQAPINAVFAGSPAIMGVIRLCTGWMVTSLPVYNDEDLMRRNENLYQIYSMRSAEDIYKILTSYKASYVVIEDSICNEVGVMKGCRVKDLLDVANDHVINED-------GDVYAYSKYGRFCHEIKMNYS----PYVNYFTRVFWNRSYSVFKI 612          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIAL-ICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN--GCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNN--SFAKYFQEKFVNPTFRVYRV 2157
            KIL S +     + I L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    +L  F+ L  +N TE    IN++ RMNI+QE+FL  LY+++    + + P+ FY+ ++  LQ + +++++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ I +      +R      LS++      ++ST LF L WQF QF++LL++ V+F L+  + +    A   Y   +  LL    +Q  N M+L S  ++  +S LI+   +   +   SF  R+  L +       L L L  +   +L    D HIF+FL  KFG G++R+FD NLY C E FG +P+  F  +S  ++    F  Y+ + +  +++A  V +H+  +   L  S+ ++   A           +   PE AY+   +    VL L   RM+YL+T +  +++S    +  V++ +      L  ++   P  I                       W  + +V  L +  + ++++  +  EL +L+EFYDPDTV+L++WI  +T     FAGSMQL+A VKL + R + NHPHYED +LR +TQ +YQ+YAK+  + V  +L+ +   ++ILEDSIC  + +  GC+L+D++D++NGH  +    S  DL     PRFC EI+       N  S+A +F   F N TF VY++
Sbjct:   43 KILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVL-PIQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNL-QPLSERLTLLAIFVSTFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAMKATWLYGIQISCLLLVCTLQFFNSMILGSLLISFNLSVLIVRKLQK-NLKTGSFLTRIWKLLLHLLLVFCLTLFLNNIIKKVLNLKSDEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLL----FYAYMFVLVVTVVTASVVAFHNLSDSTSLK-SMDQTRKRA-----------VDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFGLCSSEVWELL------LRLVHLCNPKRI-----------------------WVLRYLVPVLTLLYLCYKSWPGVMDELSELKEFYDPDTVELMTWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDKSLRERTQAVYQIYAKRSPEEVHALLRSFGTDFVILEDSICYERRHHRGCRLRDLLDVANGHEMDGPGESDPDLRPADHPRFCEEIK------RNLPSYAAHFTRVFQNKTFHVYKL 712          

Query:   22 ISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGN-----LMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISF--EAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFD-LDDVHIPRFCNEIRYLNSVVNNS-FAKYFQEKFVNPTFRVYRV 2157
            I  +  ++  + + FY+ +  E  FW+SN  ++E+ I+F+ +  +YYSYY++ +         Y L  NN T     IN + +M+++ E+    LY+  G   E I P+ FY+  V  LQ + ++++F+ S  ++ + L G+L+VA F +NR   +R+ Y +PLREN+ALP++   V      ++    +  +++F   +   ST  F + W++  +V+ L++  +  L++F           Y   + SL     +Q  N       LLS     ML+  L L   K       +F  ++  +  +      L + L  +    +   ++ H+ +FL VKFG+  ++NF +N   C E     P + F   L   +   F  Y+ + +  L+S   V +           S  E++    G         +   PE+ YH   +  +  L ++++ +++++TPY  + ++                             + S + +   L   R   +  ++     ++ +  I  +S   E F  + TEL +L+EFYDPDTV+L++WIK        FAGS QLM  +KL +   + + P Y D +L  + + +YQ+Y+K+ A+ + +IL  YK +Y+I+ED+IC  L  + GC++KD++D++NGH+     F   D L      RFC+E++     +N S +  YF   + N ++ VY+V
Sbjct:   53 IGCLAAVISGMMHVFYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTISLKTINAMQQMSLYPELIASVLYQATGS-NEVIEPVYFYIGIVFGLQGMYVTALFVTSWLMSGTWLAGMLTVAWFLINRVDTTRIEYSIPLRENWALPYFACQVAALTGYLKRNL-NTYAERFCYLLLSTSTYTFMMVWEYSHYVLFLQAVSLLLLDIFSVEQSDKVYEVYKVYIFSLFLGYLLQFENPALLVSPLLSLVGAFMLVKCLQLNGKK------GTFVAKVIKV-FEFYLLCTLPVTLNLIVKMFVPHKENEHVLKFLEVKFGLNMTKNFTLNWLLCQESLQ-APSQDFFFRLTQSSLLPF--YVLVLIICLLSMTQVFFRRMS-----GKSKKETVTLEDGR--------IGERPEIIYHVIHTLLLGSLAMLMEGLKFIWTPYVCMLAAF---------------------------GVCSPELWMTLLKWLRLRTVHPMLLALILSMAVPTIIGLSLWKEFFPRLITELTELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWTVTSLPLYSDDDLLQRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNELGTTRGCRVKDLLDIANGHV----VFEEGDKLTYSKYGRFCHEVK-----INYSPYVNYFTRVYWNRSYFVYKV 714          

Query:   85 ESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYK-IVGKF------------YERISPIE-------------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWT-------CLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLI-SALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            E++  +S++S +E+ ++FRTE GLYYSY++  I+    L   +++  + LTEYP VIN + R +++ E+ + + Y+ I+G                R+ P+              FY+  + +L  L +   FI S  ++ S LGG+++VA +  N    +RV++  PLRE+F+ PF  + +    +++R++  +   + ++   F  S + F L WQF QF++  +   +F + +  ++  +  +   +        C I + G S             T A++     +      E+      G   W            ++L+FL++ I   +D   +   +A +  I    +FD  +Y C   F +M     L  +  +  P  +V   L    ++   + VL+ +T   +                       LL N  EL +H     A   L +++ R++   TP+  I +S+  S R ++  +  +I                          H  N++              ++  +S +   ++  +   + EF +    +LI WIKHST P   FAG+M  MA++KL + RPIVNHPHYED +LR +T+ +Y +Y++K A  V   L +  V+Y +LE++ C+ ++  GC + +I D+              D  +   P  C       S++      YF   F N  +RV ++
Sbjct:  144 ENDHHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLVINTVKRFHLYPEVVIAYWYRTIIGIMNLFGIETKTCWNVTRMEPLNEVQSCEGLGDPACFYIGVIFILNGLMMGLFFIYSTYLSGSQLGGLITVACYFFNHGEATRVMWTPPLRESFSYPFLVLQMYILTIILRTS--TVHKKHYMALCF--SNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYVNMSSVALCFILMFGNSMYLSSYYSSCLLVTWAIMQKKSKIQKLGGTELQFWLIQGCFWWCG---------TIILKFLTSKICGVSDHIRLSDLIAAR--ILRYTDFDTLIYTCAPEFDFMEQATPLRYIKTLLLPLILVITYLIFKKIVRDIMCVLYTNTYVRK----------------------QLLDN-AELIFHTLQLLAFTGLAILIMRLKLFLTPHMCIMASLICSQR-LFGWLFCRI--------------------------HFENVV------------FGILTMMSIQGCANLHNQWSIMGEFTNLPQEELIHWIKHSTRPDAVFAGAMPTMASIKLSTLRPIVNHPHYEDADLRARTKIVYSVYSRKSAVEVRNNLLKLHVNYYVLEEAWCVVRTKPGCSMLEIWDVE-------------DPSNAANPPLC-------SILLKDSRPYFTTVFQNSMYRVLKI 772          

Query: 1627 EAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHI--PERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNS-FAKYFQEKFVNPTFRVYRV 2157
            E F  + TEL +L+EFYDPDTV+L++WIK        FAGS QLM  +KL +   + + P Y D +L  + + +YQ+Y+K+ A+ + +IL  YK +Y+I+ED+IC  L  + GC++KD++D++NGH+   E    +Y         RFC+E++     +N S +  YF   + N ++ VY+V
Sbjct:  317 EFFPRLITELTELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWTVTSLPLYSDDDLLQRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNELGTTRGCRVKDLLDIANGHVVFEEGDKLTYSKYG-----RFCHEVK-----INYSPYVNYFTRVYWNRSYFVYKV 488          

Query:  454 VALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGN-----LMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISL---NMVAYPSFIVYICL 1167
            VA F +NR   +R+ Y +PLREN+ALP++   V      ++    +  +++F   +   ST  F + W++  +V+ L++  +  L++F           Y   + SL     +Q  N       LLS     ML+  L L   K       +F  ++  +  +      L + L  +    +   ++ H+ +FL VKFG+  ++NF +N   C E     P + F   L   +++ +   ++ ICL
Sbjct:   10 VAWFLINRVDTTRIEYSIPLRENWALPYFACQVAALTGYLKRNL-NTYAERFCYLLLSTSTYTFMMVWEYSHYVLFLQAVSLLLLDIFSVEQSDKVYEVYKVYIFSLFLGYLLQFENPALLVSPLLSLVGAFMLVKCLQLNGKK------GTFVAKVIKV-FEFYLLCTLPVTLNLIVKMFVPHKENEHVLKFLEVKFGLNMTKNFTLNWLLCQESLQ-APSQDFFFRLTQSSLLPFYVLVLIICL 246          

Query:   85 ESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFY----------------ERISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYK-TPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFL 1116
            E++  +S++S +E+ ++FRTE GLYYSY++  ++    LN  +++  + LTEYP VIN + R N++ E+ L   Y+I  K                  E +SPIE          FYV  + +L  L ++  FI    ++ S LGG+++V  F  N    +RV++  PLRE+F+ PF  + +L    ++R+  P       I     +S +LF L WQF QFV+L +   +FA+ +  ++     +   +  +ISL+    +  GN MLL+S+  + L+  +I G     P+ +  + S    W+ +Q  G L   ++L+ +++ I    DD+HI   L  KF   S ++FD  LY C   F +M  E  L
Sbjct:  114 ENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFMLNGLMMALFFIYGTYLSGSRLGGVVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRA--PELCRGSLI--ALCISNVLFMLPWQFAQFVLLTQIASLFAVYVVGYIDTHKLQKIIYMHMISLVLCFVLMFGNSMLLTSYYASSLV--IIWGMLAMKPQFLRMNVSELSLWV-IQGCGWLFGTVILKSVTSRIFGIADDAHIGNLLTSKF--FSYKDFDTLLYTCAAEFDFMEKETPL 475          

Query: 1591 AIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL 2160
            A+V A++  +S +   +++T+   + EF +    +LI WI++ST P   FAG+M  MA+VKL + RP+VNHPHYED  LR +T+ +Y MY++K  + V + L + KV+Y ILE+S C+ +S  GC + +I D+              D D+      CN       ++      +F   F N  ++V  VL
Sbjct:  574 AVVFAILAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIRYSTKPDAVFAGAMPTMASVKLSALRPVVNHPHYEDAGLRARTKIVYSMYSRKAPEDVKKELMKLKVNYYILEESWCIRRSKPGCSMPEIWDVE-------------DPDNAGKTPLCN-------ILVKDSKPHFTTVFQNSVYKVLEVL 744          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIAL-ICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN--GCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNN--SFAKYFQEKFVNPTFRVYRV 2157
            KIL S +     + I L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    +L  F+ L  +N TE    IN++ RMNI+QE+FL  LY+++    + + P+ FY+ ++  LQ + +++++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ I +      +R      LS++      ++ST LF L WQF QF++LL++ V+F L+  + +    A   Y   +  LL    +Q  N M+L S  ++  +S LI+   +   +   SF  R+  L +       L L L  +   +L    D HIF+FL  KFG G++R+FD NLY C E FG +P+  F  +S  ++    F  Y+ + +  +++A  V +H+  +   L  S+ ++   A           +   PE AY+   +    VL L   RM+YL+T +  +++S    +  V++ +      L  ++   P  I                       W  + +V  L +  + ++++  +  EL +L+EFYDPDTV+L++WI  +T     FAGSMQL+A VKL + R + NHPHYED +LR +TQ +YQ+YAK+  + V  +L+ +   ++ILEDSIC  + +  GC+L+D++D++NGH  +    S  DL     PRFC EI+       N  S+A +F   F N TF VY++
Sbjct:   43 KILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVL-PIQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNL-QPLSERLTLLAIFVSTFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAMKATWLYGIQISCLLLVCTLQFFNSMILGSLLISFNLSVLIVRKLQK-NLKTGSFLTRIWKLLLHLLLVFCLTLFLNNIIKKVLNLKSDEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLL----FYAYMFVLVVTVVTASVVAFHNLSDSTSLK-SMDQTRKRA-----------VDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFGLCSSEVWELL------LRLVHLCNPKRI-----------------------WVLRYLVPVLTLLYLCYKSWPGVMDELSELKEFYDPDTVELMTWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDKSLRERTQAVYQIYAKRSPEEVHALLRSFGTDFVILEDSICYERRHHRGCRLRDLLDVANGHEMDGPGESDPDLRPADHPRFCEEIK------RNLPSYAAHFTRVFQNKTFHVYKL 712          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNN--SFAKYFQEKFVNPTFRVYRV 2157
            KIL   I     + I L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    ++  F+ L  +N TE    IN++ RMNI+QE+FL  LY+++    + + P+ FY+ ++  LQ + +++++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ I +      +R      LS++      ++ST LF L WQF QF++L+++ V+F L+  + +    A   Y   + SLL    +Q  N M+L S  ++  +S  I    +   +   SF  RL  L +     L L L L  +   IL    D HIF+FL  KFG+G++R+FD NLY C E FG +P   F    + + + ++I  + +    +I A  V +H+      L  S ++  V   G    G   L    PE AY+   +     L L   RM+YL+T +  +++S    +  +++ + K     S   Y P          K+  +          M +S   +++  +C   ++ +  +  EL +LREFYDPDTV+L++WI  +T     FAGSMQL+A VKL + R + NHPHYED +LR +T+ +YQ+YAK+  + V  +L+ +   Y+ILEDSIC       GC+L+D++D++NGH+ +    +  DL     PRFC EI+       N   +  YF   F N TF VY++
Sbjct:   43 KILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVL-PIQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNL-QPLSERLTLLAIFISTFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQK-NLKTGSFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKSDEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSIT---VIVAFVVAFHN------LSDSTNQQSV---GKMEKGTVDL---KPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFGLCSPEIWELLLK-----SVHLYNP----------KRICI----------MRYSVPILILLYLC---YKFWPGMMDELSELREFYDPDTVELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDSSLRERTRAVYQIYAKRAPEEVHALLRSFGTDYVILEDSICYERRHRRGCRLRDLLDIANGHMMDGPGENDPDLKPADHPRFCEEIK------RNLPPYVAYFTRVFQNKTFHVYKL 712          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKI--VGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIP 2004
            KIL   I     + I L    Y  +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    ++  FY L  +N TE    IN++ RMNI+QE+FL  LY++  V K+ E   P+ FY+ ++  LQ + +++++I S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ I +      +R      LS++      ++ST LF L WQF QF++L+++ V+F L+  + +    A   Y   + SLL    +Q  N M+L S  ++  +S  I    +   +   SF  RL  L +     L L L L  +   IL    D HIF+FL  KFG+G++R+FD NLY   E FG +P   F    + + + ++I  + +    +I A  V +H+      L  S ++  V   G    G   L    PE AY+   +     L L   RM+YL+T +  +++S    +  +++ + K     S   Y P          K+  +          M +S   +++  +C   ++ +  +  EL +LREFYDPDTV+L++WI  +T     FAGSMQL+A VKL + R + NHPHYED +LR +T+ +YQ+YAK+  + V  +L+ +   Y+ILEDSIC       GC+L+D++D++NGH P
Sbjct:   43 KILSLTIGGTIALCIGLLTSVYPATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFYGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVLPVQKYLE---PVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNL-QPLSERLTLLAIFISTFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQK-NLKTGSFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKSDEHIFKFLKAKFGLGATRDFDANLYLREEAFGLLPFNTFGRLSDTLLFYAYIFVLSIT---VIVAFVVAFHN------LSDSTNQQSV---GKMEKGTVDL---KPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFGLCSPEIWELLLK-----SVHLYNP----------KRICI----------MRYSVPILILLYLC---YKFWPGMMDELSELREFYDPDTVELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDSSLRERTRAVYQIYAKRAPEEVHALLRSFGTDYVILEDSICYERRHRRGCRLRDLLDIANGHNP 665          

Query:   19 FISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHI--PERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNS-FAKYFQEKFVNPTFRVYRV 2157
            FI  +  +   + Y  Y+ +  E  FW+SN  ++E+ I+F+ +  +YYSYY++ +         Y L  NN T     IN + +M+++ E+    LY+  G   E I P+ FY+  V  LQ + ++++F+ S  ++ + L G+L+VA F +NR   +R+ Y +PLREN+ALP++   +      ++S   +   ++F   +   ST  F + W++  +++ L+   +F L++F           Y   + SL     +Q  N  LL S  +  L+++L+L       +   SF  ++  + +       L + L  +    +   ++ H+ +FL VKFG+  ++NF +N   C E     P + F + L   +   F  YI + +   +S L V++           S+ E+I    G         +   PE+ YH   +  +  L ++++ ++Y++ PY  + ++    +  ++  + K +                       L +    L++ ++  +   I+   + K   E F  + TEL +L+EFYDPDTV+L++WIK        FAGS QLM A+KL +   + + P Y D +L  + + +YQ+Y+K+ A+ + +IL  YK +Y+I+ED+IC  +    GC++KD++D++NGH+   E    +Y         RFC+E++     +N S +  YF   + N ++ VY++
Sbjct:   16 FIGCLAAVTSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQQMSLYPELIASVLYQATGS-KEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFIINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL-NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQVISLFLLDIFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPALLVS-PLLSLVAALMLAKCLQLNVKKGSFVAKIIKV-INFYLVCTLTITLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQ-APSQDFFLRLTQSSLLPF--YILVLIICFLSMLQVIFRRIN-----GKSLKETITLEDGR--------IGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWL----------------------RLRTVHPILLALILSMAVPTIIGLSLWK---EFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPIRGCRVKDLLDIANGHMVCEEGDKLTYSKYG-----RFCHEVK-----INYSPYVNYFTRVYWNRSYFVYKI 678          

Query:   19 FISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHI--PERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            FI  +  +   + Y  Y+ +  E  FW+SN  ++E+ I+F+ +  +YYSYY++ +         Y L  NN T     IN + +M+++ E+    LY+  G   E I P+ FY+  V  LQ + ++++F+ S  ++ + L G+L+VA F +NR   +R+ Y +PLREN+ALP++   +      ++S   +   ++F   +   ST  F + W++  +++ L++  +F L+ F           Y   + SL     +Q  N  LL S  +  L+++L+L       +   SF  ++  + +       L + L  +    +   ++ H+ +FL VKFG+  ++NF +N   C E     P + F + L   +   F  YI + +   +S L V++           S+ E++    G         +   PE+ YH   +  +  L ++++ ++Y++ PY  + ++    +  ++  + K +                       L +    L++ ++  +   I+   + K   E F  + TEL +L+EFYDPDTV+L++WIK        FAGS QLM A+KL +   + + P Y D +L  + + +YQ+Y+K+ A+ + +IL  YK +Y+I+ED+IC  +    GC++KD++D++NGH+   E    +Y         RFC+E++    +  + +  YF   + N ++ VY++
Sbjct:   53 FIGCLAAVTSGMMYALYLSAYHERKFWFSNRQELEREITFQGDSAIYYSYYKDMLKAPSFERGVYELTHNNKTVSLKTINAVQQMSLYPELIASILYQATGS-NEIIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFVINRVDTTRIEYSIPLRENWALPYFACQIAALTGYLKSNL-NTYGERFCYLLMSASTYTFMMMWEYSHYLLFLQAISLFLLDTFSVEQSDKVYEVYKIYIFSLFLGYLLQFENPALLVS-PLLSLVAALMLAKCLQLNVKKGSFVAKIIKV-INFYLVCTLTITLNIIMKMFVPHKENGHMLKFLEVKFGLNMTKNFTMNWLLCQESLQ-APSQDFFLRLTQSSLLPF--YILVLIICFLSMLQVIFRRIN-----GKSLKETVTLEDGR--------IGERPEIIYHVIHTILLGSLAMVIEGLKYIWIPYVCMLAAFGVCSPELWMTLFKWL----------------------RLRTVHPILLALILSMAVPTIIGLSLWK---EFFPRLMTELMELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMRGCRVKDLLDIANGHMVCEEGDKLTYSKYG-----RFCHEVK----INYSPYVNYFTRVYWNRSYFVYKI 715          

Query:   25 SSVTLIVINLGYCFYIYST-----RESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKS-NGCQLKDIIDLSNGHIPERRYFSYF-DLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL 2160
            S+V L ++ + +C  I++       E+  W++NI +VE+ ISFRTE GLYYSYY++ +    I    Y +  +N+TE+P+ INV+ RMNI+QE+ L  LY+++        P++ + +      T S                           ++   +RV Y++PLRE+F+LPF W+ +       R +  +    K    +  +ST  F L WQF QF+ILL+S  +F + + + V     +  ++   ISLL    +Q  N M+L SF ++ + ++L L   K  +M   S   R+  +   ST  L+L + +      ++    D HI++F+  KFGIG+ R+FD  +Y C E F ++  + +      + +P ++    + L +L  A+   W +          +H+S V       +   HLLSN PELAYH   +    VL +   RM+YL+TPY  I +S   S+  ++                            +T+++H       +++  R    + ++  +   A   +  EL++L+EF+DPDTVQL+ WIK  T    +F GSMQL+A VKL + RPI NHPHYED  LR KT+ LYQ+YA+K  + V ++LK++K +YIILEDSICLA S NGC+  D++D  NGH+P+         L    + RFC+EIRY  +     F K F+    N TFRV++V+
Sbjct:   55 STVMLGLVAMFWCGLIHAKFMSQLHENWLWFTNIKEVEREISFRTESGLYYSYYKQLVHASSITQGLYEITHDNMTEHPSTINVLERMNIYQEVILSILYRVLPIKVSPQHPLQPHQSKSSAPSTAS---------------------------SKLDTTRVEYIIPLRESFSLPFLWVQIAATSFYFRPSN-NPTKDKLSIALSLVSTFFFALGWQFNQFIILLQSFSLFGVWILDLVPPKKVKMMFYIEAISLLAVCLLQFINKMILGSFVMSFIPAALFLMYIKGDDMKLCSIPSRIFKVISYSTVVLMLMVSINLSVKVLINVEADEHIYKFVLSKFGIGNPRDFDSRIYLCLEAFNFLSFDTYERLTKGMVFPFYVATHAVLLIVLCVAVLQNWSN---------HVHDSTVKDTAS--TKKSHLLSNRPELAYHIVQTVFFGVLAMSTLRMKYLWTPYMCILASFGISDYRMW----------------------------RTVLAHLKTQ-GMMVQIVRHLATLIVLAALLAIALPPVFKELEELKEFWDPDTVQLMEWIKKETPKKAAFTGSMQLLAGVKLCTGRPITNHPHYEDKQLRDKTKDLYQIYARKTPEDVHKLLKKHKANYIILEDSICLAPSRNGCRTPDLMDFHNGHLPDASNGKMEPGLVRSKVARFCDEIRYNGT----RFLKLFKPVLSNKTFRVHKVV 701          

Query:   31 VTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHH--------IRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLA-KSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL 2160
            + ++     + +Y+ +  E+  W++NI +VE+ ISFRTE GL+YSYY++ I  + I      L R+N TEYP+ IN++ RMNI+QE+ L  LYK +     +  PI FYV SV  LQ + I  IF ++  +  + L G+L+   + +N+   +RV +  PLRE FALPF W+ +       +    S + ++        ST LFC+ WQF QF++LL+   +F + + +F+     +   +  L+SL     +Q  N MLL     + L+S  I+   K  +   SS + +L  +   S   L L  +  F+  W L  + D HIF+FL  K G G+ R+FD  LY C + F  +    +    + V +P + +   + L    S   +      E+    P   +S              LLS  PELA+H   ++   +L +   RM+YL+TPY  +++      + +Y                            KT++   +N                L+C   FE F H        I+ E++DLREF+DPDTV+L+ WIK ST P  +F+GSMQL+A VKL S RP+ NHPHYED  LR KT+ +YQMY K++   V  ILK+Y+  YIILEDSICL+ K++ C   DIIDL+NG IP +       L +  +PRFC+EIR+ +      F KYF+  F N TFRVY++L
Sbjct:   59 IVMMFCGAAHSWYMRTLHENTLWFTNIKEVEREISFRTESGLFYSYYKQLIQSKSISQGVQSLVRDNHTEYPSTINILQRMNIYQEVILASLYKFLAI---QSPPIFFYVYSVFNLQAVLIGGIFCMAWMLADNWLAGVLAAIFYAINKENTTRVEFTTPLRECFALPFLWVQIAAISYFFKKNI-SRIGERISLLFIGSSTFLFCICWQFNQFIMLLQLISLFGVWVLDFIPSFKIQRVLFMQLLSLFTVFYLQYYNTMLLGGLWFSFLLSFYIVIFIKVDKPSQSSVTVKLLRVIGYSLLVLSLTFIFHFILKWFLQVDADEHIFKFLINKMGYGNPRDFDSRLYLCLDIFNMLSWSFYTSLTSGVVFPLYTIVHTVLLLYFCSIFLISSSSNTEKRLFTPETKDS--------------LLSYRPELAFHTVQATMFGILAITTMRMKYLWTPYMCVFAGFLVGGKHLY----------------------------KTVLFFTSNE--------------KLVC--IFEYFLHLLRFWMPTIQKEMEDLREFWDPDTVELMEWIKKSTKPIAAFSGSMQLLAGVKLCSGRPVTNHPHYEDKQLREKTKWIYQMYGKREPVEVYTILKKYQTDYIILEDSICLSYKTDSCSTPDIIDLNNGMIPVQGKMEP-GLVNSAVPRFCDEIRHGSP----KFTKYFKLVFSNKTFRVYKLL 710          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK--SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNN--SFAKYFQEKFVNPTFRVYRV 2157
            IL   +  +  I + L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ I    I    + L  +N TE    IN++ RMN++QE+FL  LY+I+    + + P+ FY+ ++  LQ + + ++++ S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ + +     L+R+     + ++      +++T LF L WQF QF++L+++  +F L+ F+ +S A     Y   L  LL   A+Q  N M+L S  ++   S LI  + +   +   S   RL  L +     L L  ++      IL    D HIF+FL  KFG G++R+FD NLY C E FG +P+  F  +S  ++    F +YI +   + ++A+ V + +     ++  +          + C+     ++  P++AY+   +     L L   RM+YL+T +  +++S    +  V+  I K I                         S RT++I       + +I I  +  IS++ +  I  EL +LREFYDPDTV+L++WIK +T  T  FAGSMQL+A VKL + R + NHPHYED NLR +T+++YQ+YAK+  + V RIL+ +   Y+ILEDSIC  +  S GC+L+D++D++NGHI +    +  DL     PRFC EI+       N  S+  +F   F N TF VYR+
Sbjct:   41 ILSITVGGIVAISLGLLTSVYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMIQAASIQQGLHGLVYDNKTESVRTINILERMNVYQEVFLSILYRIL-PIQQYLEPVYFYIYTLFGLQAVYVIALYVTSWLLSGTWLSGLLAACWYITNRIDTTRVEFTIPLRENWALPFFAVQIAAITYLLRN-HLQPVQERLTLMAVFIATFLFSLTWQFNQFMMLIQALALFILDCFDMLSTAKVTWLYIIQLSGLLLVCALQFFNAMILGSLLISFNASVLIARTIQ-KNLKKGSLLNRLGKLILHVLLVLCLTFLINKCIKKILNLESDEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFSRLSDTLL----FYIYIFVLFFMTVAAVVVAFRNLSGSNQVQFT-------EKMEECT-----ITLKPDVAYNLIHTVLFGCLALSTMRMKYLWTSHMCVFASFGLCSTEVWKLILKCI---------------------HLYTSQRTHVI-------KYSIPIITLLYISYKFWPGIMDELSELREFYDPDTVELMNWIKSNTPNTAVFAGSMQLLAGVKLCTGRTLTNHPHYEDKNLRERTKQIYQIYAKRSPEDVYRILRSFGTDYVILEDSICYERRHSRGCRLRDLLDIANGHIMDGLGENEPDLKPSLYPRFCEEIK------KNLPSYTLHFTRVFQNKTFHVYRL 709          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLS----SFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK--SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNN--SFAKYFQEKFVNPTFRVYRV 2157
            IL   +  +  I + L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ I    I    + L  +N TE    IN++ RMN++QE+FL  LY+I+    + + PI FY+ ++  LQ L + ++++ S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ + +     L+R T    + ++      +++T LF L WQF QF++L+++ V+F L+ F+ +  A     Y   +  LL    +Q  N M+L     SF  ++LI+  I  + K   M++     R+  L +     L   L+L      IL    D HIF+FL  KFG G++R+FD NLY C E FG +P+  F  +S  ++ Y    V   + +A +I A   L   +   + +             + C+     ++  P+ AY+   +     L L   RM+YL+T +  +++S    +  V+ K+  K + L                      S RT++I       R +I I  +  +S++ +  I  EL +LREFYDPDTV+L++WIK +T  T  FAGSMQL+A VKL + R + NHPHYED NLR +T+++YQ+YAK+  + V RIL+ +   Y+ILEDSIC  +  S GC+L+D++D++NGHI +    +  DL     PRFC EI+       N  S++ +F   F N TF VYR+
Sbjct:   44 ILSITVGGIVAISLGLLTSVYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMIQAASIQQGLHGLVYDNKTESVRTINILERMNVYQEVFLSILYRIL-PIQQYLEPIYFYIYTLFGLQALYVIALYVTSWLLSGTWLSGLLAACWYITNRIDTTRVEFTIPLRENWALPFFAVQIAAITYLLR-THLQPVRERLTLMAVFIATFLFSLTWQFNQFMMLIQALVLFILDCFDMLPTAKVTWLYIIQISGLLLVCVLQFFNSMILGSLLISFNASVLIARTIQKNLKKGSMLN-----RIGNLILHVLLVLCFTLLLNKFIKKILNLESDEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFSRLSDTLLFYVYLFVLFLMTVAAVIVAFRNLSSGSNRVQFMEKM----------EECT-----ITLKPDAAYNLIHTVLFGCLALSTMRMKYLWTSHMCVFASFGLCSTEVW-KLTLKCIHL--------------------YTSQRTHVI-------RYSIPIITLLYLSYKFWPGIMDELSELREFYDPDTVELMNWIKSNTPNTAVFAGSMQLLAGVKLCTGRTLTNHPHYEDKNLRERTKQIYQIYAKRSPEDVYRILRSFGTDYVILEDSICYERRHSRGCRLRDLLDIANGHIMDGLGENEPDLKPSLYPRFCEEIK------KNLPSYSLHFTRVFQNKTFHVYRL 713          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVL--WHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK--SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            IL   +  +  I + L    Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ I    I    + L  +N TE    IN++ RMN++QE+FL  LY+I+    + + P+ FY+ ++  LQ + + ++++ S  ++ + L G+L+   +  NR   +RV + +PLREN+ALPF+ + +     L+R T    + ++    + +++T LF L WQF QF++L+++  +F L+ F+ +  A     Y   +  LL    +Q  N M+L S  ++   S LI  + +   +   S   RL  L +     L L L++      IL    D HIF+FL  KFG G++R+FD NLY C E FG +P+  F  +S  ++ Y    V   + +A +I A   L   ++T     L    ++       + C+     ++  P+ AY+   +     L L   RM+YL+T +  +++S    +  V+ K+  K + L                      S RT++I       + +I I  +  IS++ +  I  EL +LREFYDPDTV+L++WIK +T  T  FAGSMQL+A VKL + R + NHPHYED NLR +T+K+YQ+YAK+  + V RIL+ +   Y+ILEDSIC  +  S GC+L+D++D++NGHI +    +  DL     PRFC EI+        S+  +F   F N TF VY++
Sbjct:   44 ILSITVGGIVAISLGLLTSVYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMIQAASIQQGLHGLVYDNKTESVRTINILERMNVYQEVFLSILYRIL-PIQQYLEPVYFYIYTLFGLQAVYVIALYVTSWLLSGTWLSGLLAACWYITNRIDTTRVEFTIPLRENWALPFFAVQIAAITYLLR-THLQPVQERLTFMVVFIATFLFSLTWQFNQFMMLIQALALFILDCFDMLPTAKVTWLYIIQISGLLLVCVLQFFNSMILGSLLISFNASVLIARTIQ-KNLKKGSLLNRLGKLILHVLLVLCLTLLINKFVKKILNLESDEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFSRLSDTLLFYVYVFVLFLMAVAAVIVAFWNLRTLYNTFYFLCLISGSNQVQFMEKTEECT-----ITLKPDAAYNLIHTVLFGCLALSTMRMKYLWTSHMCVFASFGLCSTEVW-KLTLKCIHL--------------------YTSQRTHVI-------KYSIPIITLLYISYKFWPGIMDELSELREFYDPDTVELMNWIKSNTPNTAVFAGSMQLLAGVKLCTGRTLTNHPHYEDKNLRERTKKIYQIYAKRSPEDVYRILRSFGTDYVILEDSICYERRHSRGCRLRDLLDIANGHIMDGLGENEPDLKPSLYPRFCEEIKK----TLPSYTIHFTRVFQNKTFHVYKL 725          

Query:   40 IVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRS-TKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYK----TPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYIC-LGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK--SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVY 2151
            + + L  C Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    I    Y L  +N TE    IN++ RMNI+QE+ L  LY+I+      + P+ FY+ +V  LQ + +  +F  S  ++ S L G L+   + LNR   +RV + + LREN++LPF+ + V      +R   +P+   Q+ + ++ ++ TL FCL WQF QF++L+++ +IF L+  +F++    +  Y   ++SLL    +Q  N M+L S  ++ ++S  IL S+     +  M+ S F   L +                     IL    D HIF+F+  KFG+G++R+FD +LY C E FG +P++ F  ++  ++ YP    Y+C L + L++ AL+ +++               +    GD  +      S   ++AY+   +    +L     RM+YL+T +   +++     + V+    + I                  N K  LV              R ++ + ++  + ++ +  +  E+ +LREFYDPDTV+L++WI   TS    FAGSMQL+A +KL + R + NHPHYED  LR +T+++YQ+YA++ A+ V R+L+     Y++LEDSIC  +  S GC+L+D++DL+NGHI +    +  DL     PRFC  I+      +  F + FQ    N TF VY
Sbjct:   33 VSLGLLCCIYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLRAPSIQEGLYELVNDNTTESKRTINILQRMNIYQEVLLSILYRIL-PIQNYLEPVYFYIYTVFALQVVYVLGLFFTSWMLSDSWLAGALTGVWYILNRIDTTRVEFTISLRENWSLPFFALQVAAITCYLRPHLRPA--HQRVVLWLVFVCTLCFCLTWQFNQFILLVQALLIFTLDALDFLT---VKSLYLVQVVSLLSVWLLQFCNSMILGSLVLSFIVSVSILNSFLIILLSVPMLLSHFYHLLPYCCK------------------ILQLRSDEHIFKFIKAKFGLGATRDFDASLYLCEEAFGLLPMDTFERLAGTLLIYP----YLCTLSVLLIVLALAAMFN---------------LRDYDGDEST-----FSMRSDIAYNLLHTVFFGLLAFSTMRMKYLWTGHMCAFAAFGVCGKEVWALCLRVI----------------HCNTKLRLV--------------RYSVPVVVLVFLYYKFWPRLSEEVSELREFYDPDTVELMNWISSKTSKRAVFAGSMQLLAGIKLCTGRVLTNHPHYEDQALRERTRQVYQVYARQSAEEVHRLLRSVGADYVVLEDSICFERRHSRGCRLRDLLDLANGHIMDGPGDNDPDLVPASHPRFCQAIKTGEPPYSTLFTRVFQ----NKTFHVY 663          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSR----QAIVIALICKISF----------EAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHI----PRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            +I+  FI  +  +   + Y  Y+ +  E  FW+S+  ++E+ I+F+   GLYY YY+  +         Y L R+N T     IN + +++++ E+    LY+++G     I P+ FY+  V  LQ + ++++FI S  ++ + + G+L+VA + +NR   ++V Y +PLR+N+ALP++   V      + ++  SA ++ F   +  ++T  F + W+   +V+ ++   +  L+ F+ V        +   L SLL    +Q     LLS   +++LI+SL+   Y    M       RL  + +         +   +L   IL  N +  I +FL VKFG+ ++  F  NL  C EGF   P + F + L   +   F  Y+ + L  LIS +  ++            +  S+    G         +   PE+ YH   +     L +M Q  +YL+TPY   ++                    +F    P                    L   +  W R      +V+ALI   +           E F  + +EL +++EFYDPDTV+L++WIK        FAGS  L+  VKL +  P+ + P Y D NL  +++  YQ+YA + A+ V ++L   K SYII+E+ +C  ++   GC++KD++D +NGH+        +D  +++      RFC+EI+   S   N    YF   F N ++ VYRV
Sbjct:  108 RIVKVFIGCLAAVTCGMMYAVYLSTYHERKFWFSSRQEMEREITFQGGSGLYYYYYKHMLFASSFERGVYELTRDNRTVSGQTINAVEQLSLYPELLSSLLYRLIGS-QNAIEPVYFYIGVVFGLQAVYVTALFICSWVMSGTWVAGMLTVAWYIINRPDTTKVDYAIPLRDNWALPYFSCQVAALTGFLSNSISSA-TEMFCYLLMSVTTFSFIVMWEHSHYVLFVQGVALLLLDCFDLVPPRKTADIHKVYLSSLLLAYVLQYQRPSLLSCPLLSLLIASLLA-RYLQQNMKMGPLVARLMKIVLHLYLVFTTGITFNYLVKKILPTNQNDFILKFLEVKFGLNTTTEFIPNLLLCEEGFQ-SPGQDFFLRLTQASVLPF--YVLVLLVCLISTMQTIYRRLS-----GERLKGSVRMEDGR--------IGERPEVIYHVLHTLLFGALAMMFQGTKYLWTPYVCAFT--------------------AFGVCSP-------------------ELWMTVFRWIRLRSVHPVVLALILSTAVPTIIGFSLWREYFPRVLSELTEVQEFYDPDTVELMNWIKSQAPLAAVFAGSPALLGTVKLCTGWPVTSLPLYTDLNLLQRSESTYQVYAMRSAEEVYKLLTAQKSSYIIIEEELCNEMSPVRGCRIKDLLDYANGHM-------VYDQGEMYTFSKHGRFCHEIKMNYSPYTN----YFTRVFWNRSYHVYRV 776          

Query: 1051 NFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHI----PRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
             F  NL  C EGF   P + F + L   +   F  Y+ + L  LIS +  ++            +  S+    G         +   PE+ YH   +     L +M Q  +YL+TPY   +++    +  ++  + + I  L  ++   PV +         ++S     I     W               E F  + +EL +++EFYDPDTV+L++WIK        FAGS  L+  VKL +  P+ + P Y D NL  +++  YQ+YA + A+ V ++L   K SYII+E+ +C  ++   GC++KD++D +NGH+        +D  +++      RFC+EI+   S   N    YF   F N ++ VYRV
Sbjct:  325 EFIPNLLLCEEGFQ-SPGQDFFLRLTQASVLPF--YVLVLLVCLISTMQTIYRRLS-----GERLKGSVRMEDGR--------IGERPEVIYHVLHTLLFGALAMMFQGTKYLWTPYVCAFTAFGVCSPELWMTVFRWI-RLRSVH---PVVL-------ALILSTAVPTIIGFSLWR--------------EYFPRVLSELTEVQEFYDPDTVELMNWIKSQAPLAAVFAGSPALLGTVKLCTGWPVTSLPLYTDLNLLQRSESTYQVYAMRSAEEVYKLLTAQKSSYIIIEEELCNEMSPVRGCRIKDLLDYANGHM-------VYDQGEMYTFSKHGRFCHEIKMNYSPYTN----YFTRVFWNRSYHVYRV 647          

Query:    4 KILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFV 726
            +I+  FI  +  +   + Y  Y+ +  E  FW+S+  ++E+ I+F+   GLYY YY+  +         Y L R+N T     IN + +++++ E+    LY+++G     I P+ FY+  V  LQ + ++++FI S  ++ + + G+L+VA + +NR   ++V Y +PLR+N+ALP++   V      + ++    +S  F   +  ++T  F + W+   +V+ ++   +  L+ F+ V
Sbjct:   41 RIVKVFIGCLAAVTCGMMYAVYLSTYHERKFWFSSRQEMEREITFQGGSGLYYYYYKHMLFASSFERGVYELTRDNRTVSGQTINAVEQLSLYPELLSSLLYRLIGS-QNAIEPVYFYIGVVFGLQAVYVTALFICSWVMSGTWVAGMLTVAWYIINRPDTTKVDYAIPLRDNWALPYFSCQVAALTGFLSNS----ISSMFCYLLMSVTTFSFIVMWEHSHYVLFVQGVALLLLDCFDLV 276          

Query:   31 VTLIVINLGYCFYIYSTR---ESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKI----VGKFY------------ERISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSF-SGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIE 1107
            +T+++I   Y  ++Y      E++  +S++S +EK ++FRTE GLYYSY++  I+    LN  +++  + LTEYP +IN + R N++ E+ L   Y+I    +G F             E + P++          FYV  V LL  + +S  +I    ++ S  GG+++V+ F  N    +RV++  PLRE+F+ PF  + +L    ++ S KPS    +       +S ++F L WQF QFV+L +   +FA  +  ++S    +    T ++SL     +  GN MLL+SF  + LIS  I G     E   +SF SG LTW+ MQ    ++  ++L+ L   +L  +DD+HI   +  KF   S ++FD  +Y C   F +M  E
Sbjct:   71 ITVLIIGENYTVFLYHLFHLFENDRHFSHMSGLEKEMAFRTEMGLYYSYFKTVIEAPSFLNGLHLIMNDRLTEYPLIINTLKRFNLYPEVVLASWYRIYTTVMGYFKIPTKMCWSINRGEGLEPVDSCEGMGDPAYFYVTFVFLLNGVMMSLFYIYGTYLSGSHAGGVITVSSFFFNHGESTRVMWTPPLRESFSYPFLVLQMLLLTYIL-SRKPS----RNAVLALCVSNVMFMLPWQFAQFVLLTQVASLFATYILGYLSPDKMQTVLITHMVSLGVCFVLMFGNSMLLTSFYASSLIS--IWGVIYLRERFITSFGSGLLTWV-MQCVAWVITTVILKLLLALVLGASDDAHISSLIKSKF--TSYKDFDTMMYTCAAEFDFMEAE 449          

Query: 1594 IVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSN----GHIP 2004
            IV  ++  ++ +   +++ +   + EF +     L+ WIK +T  +  FAG+M  MA+VKL + R IVNHPHYED  LR +T+ +Y MY++K  + V R L + +V + ILEDS C  +S  GC + +I D+ +    G IP
Sbjct:  541 IVFGILSIMTVQGVANLQNQWGIIGEFSNLPQEDLLEWIKENTPQSAVFAGAMPTMASVKLSAGRAIVNHPHYEDAGLRSRTKLVYAMYSRKPVEEVKRNLVKLQVDFFILEDSWCTRRSRPGCSMPEIWDVEDPGNAGKIP 682          

Query:   64 FYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKI----VGKFY------------ERISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILL-------------QNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIE-KFLISLNMVAYPSFIVYICLGLALLISALSVL 1203
            ++++   E++  +S++S +EK ++FRTE GLYYSY++  I+    LN  +++  + LTEYP +IN + R N++ E+ L   Y+I    +G F             E + P++          FYV  V LL  + +S  +I    ++ S  GG+++V+ F  N    +RV++  PLRE+F+ PF  + +L    ++ S KPS    +       +S ++F L WQF QFV+L +             S+     Y + C +SL     +  GN MLL+SF  + LIS  +  +                +L       ++  + +     W++               +DD+HI   +  KF   S ++FD  +Y C   F +M  E  FLI +   A P  +VY  L L +  + L+VL
Sbjct:   62 YHLFHLFENDRHFSHMSGLEKEMAFRTEMGLYYSYFKTVIEAPSFLNGLHLIMNDRLTEYPLIINTLKRFNLYPEVVLASWYRIYTTVMGYFKIPTKMCWSINRGEGLEPVDSCEGMGDPAYFYVTFVFLLNGVMMSLFYIYGTYLSGSHAGGVITVSSFFFNHGESTRVMWTPPLRESFSYPFLVLQMLLLTYIL-SRKPS----RNAVLALCVSNVMFMLPWQFAQFVLLTQVS-----------SNRRVITYCFVC-VSLGVCFVLMFGNSMLLTSFYASSLISIWVSDT---------------MYLQCVELVCVVCVVQVMQCVAWVITTVILKLLLALVLGASDDAHISSLIKSKF--TSYKDFDTMMYTCAAEFDFMEAEVSFLIQVP--AGPKKVVYHSLQL-VAFAVLAVL 444          

Query: 1594 IVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSN----GHIP 2004
            IV  ++  ++ +   +++ +   + EF +     L+ WIK +T  +  FAG+M  MA+VKL + R IVNHPHYED  LR +T+ +Y MY++K  + V R L + +V + ILEDS C  +S  GC + +I D+ +    G IP
Sbjct:  481 IVFGILSIMTVQGVANLQNQWGIIGEFSNLPQEDLLEWIKENTPQSAVFAGAMPTMASVKLSAGRAIVNHPHYEDAGLRSRTKLVYAMYSRKPVEEVKRNLVKLQVDFFILEDSWCTRRSRPGCSMPEIWDVEDPGNAGKIP 622          

Query:   37 LIVINLGYCF--YIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKP--SALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCL---ISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGD---FCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK--SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL 2160
            L+ I  G C   Y+ +  E+  W+SNI +VE+ ISFRTE GLYYSYY++ +     L     L  +N TE    IN++ RMNI+QE+ +G LY  +      I P+ FY+++V  LQ L + ++ + +  ++ + L G+L+   FT+NR   +R  + + LREN+ALPF    V      +R         +Q+ +    ++ST +F L WQF QFV+L+++  ++ L   +    A AR   W      +S+L    +Q  N M+L S T++ L+++  L     P++    F  R++ L++       L L + F +  +L    D HIF+FL  KFG+G++R+FD  LY C + FGW+P + F+       +P +     L LA+     S              S   +  G GGD     +G   +    P+L Y+   +    +L L   RM+YL+T +  ++++   S+  ++   A+ +                       + + R   + + +  +R  +   L+     +A   +R E+ +LREFYDPDTV L++WIK +T P   FAG+MQLMA VKL + R + NHPHYED  LR +T ++YQ+YA++    V  +L      Y++LEDS+C  +    GC+L+D++D++NG + E    +  DL      RFC+EI+      + +FA+ F+  F N TF VYR+L
Sbjct:   10 LVGIASGLCHAKYLDTLHENELWFSNIQEVEREISFRTECGLYYSYYKQLLQAPSFLQGIRELVYDNRTESLRTINLLQRMNIYQEVIMGLLYCAL-PLQGWIEPVYFYIHAVFQLQGLYVVALHVTAWLLSGTWLAGLLAATWFTVNRLDTTRAEFTVSLRENWALPFLACQVAAVTCYLRPNLKLRQECAQRPVLAAVWLSTFVFSLAWQFNQFVLLIQALALYGLRCLQL---APARKVDWVLAGQTVSMLLVCLLQFLNPMILGSLTLSFLLATF-LARRLQPDLEMGGFWRRISCLALHLLIVTSLTLAINFGAKVLLQLQSDEHIFKFLKAKFGLGNTRDFDAKLYLCEDAFGWLPPDTFVRLSRTAVFPVYT----LALAVCGIGASAAVFRKLRYGSSESSCGAARRGPGGDEMRTATGARDVFLR-PDLLYNLAHTLLFFLLALSTMRMKYLWTSHMCVFAAFAVSDTGLWAATAQAL----------------------GVSNRRLFCVPEQLSKARYVVPALLLLYTLVQAAPRVRREMGELREFYDPDTVDLMNWIKQATPPDAVFAGTMQLMAGVKLCTGRVLTNHPHYEDKTLRERTLQVYQVYARRSPAEVHAMLLSLGAHYVVLEDSVCYERRHGRGCRLRDLLDVANGQVMEGEGPNDADLTAPTHGRFCHEIK----AQSPAFARQFRAVFSNNTFHVYRIL 693          

Query: 1534 TLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDL 1986
            +L+  +  L     +W    + +  +  +S +   +I  +  ++ EF + +   L++WIK  T     FAG+M  MA++KL + R IVNHPHYED  LR +T+K+Y +Y++K A  V  IL++  V Y++LEDS C  ++  GC L +I DL
Sbjct:   16 SLLCSKKTLGEPRRKWLAHGLALVTVALMSVQGTSNIHAQWANVGEFSNVEQEDLVTWIKSHTPEDAVFAGAMPTMASIKLSTGRAIVNHPHYEDAGLRARTKKVYSVYSRKGAAEVKGILQEMGVDYLVLEDSWCTRRTKPGCSLPEIWDL 167          

Query:  148 QGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIV-------------------GKFYERISPIE-------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLIS 846
            QGLYYSYY+   +     +   ++ R+ LTEYP VIN + R N++ E+ LG +Y+                     G     IS  E       FYVN V  L  L +S  F+    ++ S+ GG+++V  F  N    +RV++  PLRE+F+ PF  + +L    ++R  KP    +K    +   +T+ F L WQF QFV+L +   +FA+ +  ++     + +    ++ L+ +  +  GN MLLSSF  A L++
Sbjct:    1 QGLYYSYYKTIAEAPTFWSGLDMIMRDRLTEYPQVINTLKRFNLYPEVILGGMYRTYLAVTNSLGIQTVQCWTVNRGNMLSAISSCEGMGDIAYFYVNMVFFLNGLMMSVFFLYGTYLSGSVAGGLVAVLSFFFNHSEATRVMWTPPLRESFSYPFLVLQMLLVTRVLR--KPQL--EKLTLGMLAGATVCFVLCWQFAQFVLLTQVACLFAVYILGYIDAEKMKTFVLLNVLCLVVSCTLMFGNEMLLSSFYAASLVA 255          

Query:   46 INLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSL-ILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAY---HFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAK-SNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL 2160
            +   Y  Y+    E++ W+SNI  VE+ ISFRTE GLY+SYY++ +    I    Y L  +N TE+   IN++ R NI+QE+ L  LY+ +    E +  + FY+NSV  L  L I +++  +  ++ S L G+L+   +  N+   +R+VY +PLRE+F  PF +   + F           L+Q        +++  F L WQF QF++LL+    F +    F      +  Y   + SLL   AM  GN M+L S  ++  +++L I+G  K P   + +   RL  L +     L L   L  L   IL    D HIF+F+  K G    R+FD  LY C   F  +P E +    + + +P ++  I        S +S   H T                           +L+  PEL Y      +  AM V TL   R ++L+TP+  +    F +  + +    + +++ + I ++P V +                                   K + E    +R       EF+DPDTV+L++WIK ST P  SF GSMQL+A VKL + R + NHPHYE+  LR +T+++YQ+YA++  + V  IL  +  +Y+ILE+SIC ++   GC+L DI+D+ NGH+ E          D  +PRFC+ I+  +S    +F +YF+  F N TF +Y+VL
Sbjct:   54 VGYKYALYVKELHENDMWFSNIGQVEREISFRTESGLYFSYYKQLVLAPSITKGLYDLSHDNTTEHLRTINILERFNIYQEVILAVLYRTIPGIQESVEYVYFYINSVFALHALYIVALYCSAWILSGSWLAGLLAACFYIFNKDDTTRIVYTIPLRESFGFPFLFTQ-MAFITYFLKRDIGRLAQVACVLGIALNSFFFTLVWQFAQFILLLQCFAFFGVYSLGFTPKHKVKILYVVVIGSLLLVCAMMFGNDMMLCSLALSFSVAALVIMGVQKEPYAPNPTLLIRLVKLVLNIVLVLFLMFALTALIKTILNVESDEHIFKFVKAKLGYDIGRDFDSLLYLCEPAFQMLPRETYQRLTSGIVFPCYVPLIPSP-----SRISNPHHMT---------------------------ILNEQPELVYCTIQTVLYGAMAVTTL---RFKFLWTPHMCV----FGAGTLCHQGFWRFVLERAGI-HKPSVRL-----------------------------------KPALEELKELR-------EFHDPDTVELMNWIKTSTPPGSSFTGSMQLLAGVKLCTDRHVTNHPHYENKFLRMRTKQVYQVYARRTPQEVHEILITHGANYVILENSICYSRMRRGCKLSDILDMDNGHVIEGGQ-PREGSRDPSVPRFCDAIKRDDS----AFRRYFRLVFENRTFYMYKVL 675          

Query:   28 SVTLIVINLGYCF----YIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKI----VGKFYER------------ISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCY-YWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSN 1992
            +VT++++   + F    ++    E+  ++S++S +E+ +SFRTE GLYYSYY+  ++    L+  + +   N+TEYP+ +N + R N++ E+ L   ++I      KF  +            + P++          FYV S+  L  L ++  FIL   ++ S+LGG+L    +  N    +RV++  PLRE+F+ P+    +L     +RS K   ++ + I  +  M+T LF + WQF QF +L ++  +F + +  F++ AD  C   +  L++ L   A+Q GN MLLSSF ++ +IS+L++   K    +H      L W + Q  G     L ++     +L   DDS        KF   S R+F   LY C   F ++  E  +     +  PS IV     +A + ++    W   ++ +    S  E   GA G   +   H      E  YH   + A +++ +++ R++   TP   + +S+  S +             SF+           D  +                   QAIVIALI  +S + F +++T+     E+ +P+  +L+ +I   T     FAG+M  MA VKL + R +VNHPHYED  +R +T K+YQ++++K    V   L    V+++I++   C+ +   GC + D+ DL +
Sbjct:   53 AVTVVILACTFGFLNSWHVSRMFENERFFSHLSALERELSFRTEMGLYYSYYKTMVEAPTFLDGLHAVMNCNVTEYPDTVNTLKRFNLYPEVILAGKFRIFEWLASKFEYQTKTCYTVNRGYGLPPVQSCEGLGELSFFYVYSIFFLTGLMMACFFILCFYLSGSILGGVLGTLCYFFNHGEATRVMWTPPLRESFSYPYLVAQLLVVTFTLRSVK---VTWRHITLV-SMTTALFMIPWQFAQFALLTQTCALFVVYIMHFIT-ADKFCKILYGLLVAHLLNFAVQFGNSMLLSSFFMSAVISALVVA--KAESQIHKLPYQLLIW-ATQGLGFAAGTLGIKVAVAKVLSIADDS--------KFT--SYRDFHTLLYTCAPEFDFLDQEAPVKLTKTLLLPSAIVAASAVIAKVGASEWEYWVRGKKSQVKSDSADEHDEGAQGQEANPRPH-----AEYVYHVLQAMAFVLMAVIIMRLKLFGTPALCVLASLVASRQF-----------FSFL----------GDRRR------------------HQAIVIALIAVMSVQGFSNLKTQFNTTGEYNNPEMEELVEFITTRTQKDAVFAGAMPTMATVKLSTGRAVVNHPHYEDVGIRERTHKVYQIFSRKPPHVVWNTLDSMGVTHVIIDAQWCMGRPKPGCGMSDMWDLED 677          

Query:   61 CFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQE 288
            C+++    E+  ++S++S +E+ +SFRTE GLYYSYY+  ++    L+  + +   N+TEYP+ +N + R N++ E
Sbjct:   30 CWHVSRMFENERFFSHLSALERELSFRTEMGLYYSYYKTMVEAPTFLDGLHAVMNCNVTEYPDTVNTLKRFNLYPE 105          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVG-KFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            I+++ +     + + L  C Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    I      +  +NLTE    IN++ RMNI+QE+FL  LY+++  K Y  + P+ FY+ +V  LQ + + ++++ +  ++ S L G L+   + LNR   +RV + + LREN++LPF  + V T    +R  + ++  QK + ++ Y++T  FCL WQF QF++L+++ +I+ L+  + ++       Y   +  LL    +Q  N M+L S  ++ ++++L +   +T ++       RL+ + + S    LL   + +L+   L    D HIF+F+  KF +  +R+FD +LY C E FG +P++    ++  ++ YP     + L   L ++A   L            S  E     GG      G   +   ++AY+   +    ++     RM+Y++T +    ++                             + S++ +   L + R N    L+   R A+ + ++  + F+ +  +  EL +LREFYDPDTV+L++WI   T     FAGSMQL+A +KL + R + NHPHYED +LR +T+++YQ+YA++  + V  IL+     Y++LE+SIC       GC+L+D++DL+NGHI +    +  DL     PRFC  I+   +     F++ FQ    N TF VYR+
Sbjct:   47 IIWTSVGLSVSVGLGLLCCIYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPSIQEGLLEMIHDNLTESRRTINLLQRMNIYQEVFLSVLYRLLPIKTY--LEPVYFYIYTVFSLQAVYVIALYLTAWLLSGSWLAGALAGLWYILNRVDTTRVEFTISLRENWSLPFLALQVATITCYLRP-QLTSFQQKVMVWLMYVTTFCFCLTWQFNQFILLVQALIIYTLDCVDLLTTTQVTTLYLVQVSGLLSVWLLQFFNSMILGSLVLSFIVAALFVRHCQT-DLKVGGLLVRLSKILLHSVLVFLLTFTINYLTKKALQVRSDEHIFKFIKSKFALRPTRDFDASLYLCEEAFGLLPLDTLERLADTLLLYPYVPTLLLLSGTLAVAAFRNL------------SCSE-----GGSAEEKKGAAEAFRSDVAYNLLHTLLYGLVAFSTMRMKYIWTGHMCAVAAH---------------------------GVCSAELWTLLLRTLRCN-SRTLLRIVRCAVPLLIVGFLYFKFWPKLMNELSELREFYDPDTVELMTWISTKTPKQAVFAGSMQLLAGIKLCTGRVLTNHPHYEDKDLRDRTRQVYQVYARRSPEEVYGILRAAGADYVVLENSICYERRHRRGCRLRDLLDLANGHIMDGPGENDPDLTPAEHPRFCEAIQTDGAAYTALFSRTFQ----NKTFHVYRL 714          

Query:    7 ILYSFISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVG-KFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALS-QKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRV 2157
            I+++ +     + + L  C Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    I      +  +NLTE    IN++ RMNI+QE+FL  LY+++  K Y  + P+ FY+ +V  LQ + + ++++ +  ++ S L G L+   + LNR   +RV + + LREN++LPF  + V T    +R   P   S Q+ + ++ Y++T  FCL WQF QF++L+++ +I+ L+                 L  LL    +Q  N M+L S  ++ ++++L         + H   S     L ++S                      D HIF+F+  KF +  +R+FD +LY C E FG +P++    ++  ++ YP     + L   L ++A   L            S  E     GG      G   +   ++AY+   +    ++     RM+Y++T +    ++                             + S++ +   L + R N    L+   R A+ + ++  + F+ +  +  EL +LREFYDPDTV+L++WI   T     FAGSMQL+A +KL + R + NHPHYED +LR +T+++YQ+YA++  + V  IL+     Y++LE+SIC       GC+L+D++DL+NGHI +    +  DL     PRFC  I+   +     F++ FQ    N TF VYR+
Sbjct:   37 IIWTSVGLSVSVGLGLLCCIYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPSIQEGLLEMIHDNLTESRRTINLLQRMNIYQEVFLSVLYRLLPIKTY--LEPVYFYIYTVFSLQAVYVIALYLTAWLLSGSWLAGALAGLWYILNRVDTTRVEFTISLRENWSLPFLALQVATITCYLR---PQLTSFQQVMVWLMYVTTFCFCLTWQFNQFILLVQALIIYTLDYL---------------LPGLLSVWLLQFFNSMILGSLVLSFIVAALF--------VRHCQVSSDDKALQVRS----------------------DEHIFKFIKSKFALRPTRDFDASLYLCEEAFGLLPLDTLERLADTLLLYPYVPTLLLLSGTLAVAAFRNL------------SCSE-----GGSAEEKKGAAEAFRSDVAYNLLHTLLYGLVAFSTMRMKYIWTGHMCAVAAH---------------------------GVCSAELWTLLLRTLRCN-SRTLLRIVRCAVPLLIVGFLYFKFWPKLMNELSELREFYDPDTVELMTWISTKTPKQAVFAGSMQLLAGIKLCTGRVLTNHPHYEDKDLRDRTRQVYQVYARRSPEEVYGILRAAGADYVVLENSICYERRHRRGCRLRDLLDLANGHIMDGPGENDPDLTPAEHPRFCEAIQTDGAAYTALFSRTFQ----NKTFHVYRL 659          

Query:   25 SSVTLIV-INLGY--CFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVG-KFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKF-LISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSIC--LAKSNGCQLKDIIDLSNGH 1998
            +SV L V + LG   C Y+ +  E++ W+SNI +VE+ ISFRTE GLYYSYY++ +    I      +  +NLTE    IN++ RMNI+QE+FL  LY+++  K Y  + P+ FY+ +V  LQ + + ++++ +  ++ S L G L+   + LNR   +RV + + LREN++LPF  + V T    +R  + ++  QK + ++ Y++T  FCL WQF QF++L+++ +I+ L+  + ++       Y   +  LL    +Q  N M+L S  ++ ++++L +   +T ++       RL+ + + S    LL   + +L+   L    D HIF+F+  KF +  +R+FD +LY C E FG +P++    ++  ++ YP     + L   L ++A   L            S  E     GG      G   +   ++AY+   +    ++     RM+Y++T +    ++                             + S++ +   L + R N    L+   R A+ + ++  + F+ +  +  EL +LREFYDPDTV+L++WI   T     FAGSMQL+A +KL + R + NHPHYED +LR +T+++YQ+YA++  + V  IL+     Y++LE+SIC       GC+L+D++DL+NGH
Sbjct:   50 TSVGLSVSVGLGLLCCIYVATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPSIQEGLLEMIHDNLTESRRTINLLQRMNIYQEVFLSVLYRLLPIKTY--LEPVYFYIYTVFSLQAVYVIALYLTAWLLSGSWLAGALAGLWYILNRVDTTRVEFTISLRENWSLPFLALQVATITCYLRP-QLTSFQQKVMVWLMYVTTFCFCLTWQFNQFILLVQALIIYTLDCVDLLTTTQVTTLYLVQVSGLLSVWLLQFFNSMILGSLVLSFIVAALFVRHCQT-DLKVGGLLVRLSKILLHSVLVFLLTFTINYLTKKALQVRSDEHIFKFIKSKFALRPTRDFDASLYLCEEAFGLLPLDTLERLADTLLLYPYVPTLLLLSGTLAVAAFRNL------------SCSE-----GGSAEEKKGAAEAFRSDVAYNLLHTLLYGLVAFSTMRMKYIWTGHMCAVAAH---------------------------GVCSAELWTLLLRTLRCN-SRTLLRIVRCAVPLLIVGFLYFKFWPKLMNELSELREFYDPDTVELMTWISTKTPKQAVFAGSMQLLAGIKLCTGRVLTNHPHYEDKDLRDRTRQVYQVYARRSPEEVYGILRAAGADYVVLENSICYERRHRRGCRLRDLLDLANGH 665          

Query:   55 GYCFYIYSTR--ESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKI----VGKFY------------ERISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIE---KFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSN----GHIP--------ERRYFSYFDLDDVH 2046
            GY  + + +R  E++  +S++S++EK ++FRTE GLYYSYY+  I+    L   +++  + LTE+P VIN + R N++ E+ L   Y++    +G F             E +SP++          FYV  V LL  + +S  FI    ++ S LGGI++  LF  N    +RV++  PLRE+FA PF  + +L    ++R+  PS    +       +S + F L WQF QFV+L +   +FA  +  +++ A  +    T +++L     +  GN MLL+SF  + LIS  ++ + +          G + WL MQ    +   ++L+F+ + IL  +DD+HI   +  KF   S ++F   +Y C   F ++ +E   ++L +L +      +  I     L    +  L H+ +   ++       +V  G               EL YH     A  +L +++ R++   TP+  I  S+  S R ++  I +++                                        Q++V+A+I  ++ +   +++ +   + EF +    +L+ WI+ +T P   FAG+M  MA+VKL + RPIVNHPHYED  LR +T+ +Y MY++   + V + L +  V Y ILEDS C  ++  GC + +I D+ +    G IP         R YF+    +D++
Sbjct:   78 GYLHWYHLSRLFENDRHFSHLSNLEKEMAFRTEMGLYYSYYKTIIEAPTFLEGLHMIMNDRLTEHPLVINTLKRFNLYPEVVLASWYRMYTSTMGYFGIPTKMCWSINRGEGLSPVDSCEGLGDPAYFYVTCVFLLNGVMMSLFFIYGAYLSGSRLGGIVTTLLFFFNHGESTRVMWTPPLRESFAYPFLVLQMLLLTYILRTRSPS----RTALVALGISNVCFMLPWQFAQFVLLTQVASLFASYILGYLAAAKMQSILVTHMVTLGVCFLLMFGNSMLLTSFYASSLISIWVIIALRD-RFAQIFKPGIIIWL-MQGLAWVGSTVLLKFVLSTILGASDDAHISGLIKSKFT--SYKDFHTMMYTCAAEFDFIELETPVRYLKTLLLPVNLLVLALITA--RLFQDIIRTLRHEEKASVKVDDDGGTDLVVKG---------------ELVYHSLQLLAFALLAVLIMRLKLFLTPHMCIMGSLLCS-RQLFGWIGERL--------------------------------------KHQSVVLAVIAMMAVQGVANLQAQWAIIGEFSNLPQEELLDWIQENTRPDSVFAGAMPTMASVKLSTGRPIVNHPHYEDAGLRERTKLVYSMYSRMSGETVKKNLMKLGVDYFILEDSWCTRRTRPGCSMPEIWDIEDPQNVGKIPLCTHMSRSSRPYFTTVFSNDIY 721          

Query:   85 ESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKI----VGKFY------------ERISPIE----------FYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSN-GCQLKDIIDLSN----GHIP--------ERRYFSYFDLDDVH 2046
            E++  +S++S++EK ++FRTE GLYYSYY+  I+    L   +++  + LTE+P VIN + R N++ E+ L   Y++    +G F             E +SP++          FYV  V LL  + +S  FI    ++ S LGGI++  LF  N    +RV++  PLRE+FA PF  + +L    ++R+  PS    +       +S + F L WQF QFV+L +   +FA  +  +++ A  +    T +++L     +  GN MLL+SF  + LIS  +       +   + F   +    MQ    +   ++L+F+ + IL  +DD+HI   +  KF   S ++F   +Y C   F ++ +E  L+                                      +  I   + G     CS   ++ + + +L YH     A  +L +++ R++   TP+  I  S+  S R ++  I +++                                        Q++V+A+I  ++ +   +++ +   + EF +    +L+ WI+ +T P   FAG+M  MA+VKL + RPIVNHPHYED  LR +T+ +Y MY++   + V + L +  V Y ILEDS C  ++  GC + +I D+ +    G IP         R YF+    +D++
Sbjct:   21 ENDRHFSHLSNLEKEMAFRTEMGLYYSYYKTIIEAPTFLEGLHMIMNDRLTEHPLVINTLKRFNLYPEVVLASWYRMYTSTMGYFGIPTKMCWSINRGEGLSPVDSCEGLGDPAYFYVTCVFLLNGVMMSLFFIYGAYLSGSRLGGIVTTLLFFFNHGESTRVMWTPPLRESFAYPFLVLQMLLLTYILRTRSPS----RTALVALGISNVCFMLPWQFAQFVLLTQVASLFASYILGYLAAAKMQSILVTHMVTLGVCFLLMFGNSMLLTSFYASSLISIWV-------KKAAALFGLNVLKQLMQGLAWVGSTVLLKFVLSTILGASDDAHISGLIKSKFT--SYKDFHTMMYTCAAEFDFIELEVMLV------------------------------------LFYNQIRAQMTG-----CSQPFNVKTLFLQLVYHSLQLLAFALLAVLIMRLKLFLTPHMCIMGSLLCS-RQLFGWIGERL--------------------------------------KHQSVVLAVIAMMAVQGVANLQAQWAIIGEFSNLPQEELLDWIQENTRPDSVFAGAMPTMASVKLSTGRPIVNHPHYEDAGLRERTKLVYSMYSRMSGETVKKNLMKLGVDYFILEDSWCTRRTRPGCSMPEIWDIEDPQNVGKIPLCTHMSRSSRPYFTTVFSNDIY 620          

Query:  271 MNIWQEIFLGFLYKIVGKFYERISPIEFYVNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXLHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSNGCQLKDIIDLSNGHIPERRYFSYFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL 2160
            MNIWQEIFLGFLYKIVGKFYERISPIEFYVNSVILLQTLSISSIFILSLSINYSLLGGILSVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRLLLALVLRFLSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTEEEEELHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSNGCQLKDIIDLSNGHIPERRYFS FDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL
Sbjct:    1 MNIWQEIFLGFLYKIVGKFYERISPIEFYVNSVILLQTLSISSIFILSLSINYSLLGGILSVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHADARCYYWTCLISLLGTSAMQMGNLMLLSSFTVAMLISSLILGSYKTPEMMHSSFSGRLTWLSMQSTGRLLLALVLRFLSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTEEEEELHPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQYKVSYIILEDSICLAKSNGCQLKDIIDLSNGHIPERRYFSDFDLDDVHIPRFCNEIRYLNSVVNNSFAKYFQEKFVNPTFRVYRVL 630          

Query:   34 TLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERISPIEFYVN 363
             +I+ + GYCFYIYSTRE NFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILN FYVLYRNNLTEYPNVINVINRMNIWQ IFLGFLYKIVGKFYE IS +EFYVN
Sbjct:  458 NMIIKSCGYCFYIYSTREFNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNGFYVLYRNNLTEYPNVINVINRMNIWQGIFLGFLYKIVGKFYESISLVEFYVN 567          

Query:   19 FISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERIS-------------------------PIEFYVNXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHAD--ARCYYWTCLISLLGTSAMQMGNLMLLSS-FTVAMLISSLILGSYK-TPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXL---HPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQ-YKVSYIILEDSICLAKSN--GC---QLKDIIDLSN-GHIP 2004
            F+ S  +I   L Y    Y  +E+N  +S++S++E+ +SFRTE G YYS+Y++ I      NS  VL ++N+TEYP+ IN + R N++ E+F+G LYK        +                          P  FYVN ++L+    +S  F+L     + + LGG+++ A +  N    +RV +  PLRE+F+ PF  I       ++++   + +S    +  F +STL+  L WQF QF +L +   IF   +           +  Y   LI       +Q GN +LL+   T  ++++ +I+G    +   + +S    L W+ +  +  L   L+   +   + +++DD H+F  L  KF   +S  FD  LY C   F +  +   +  LN            L LA L S L +L++   +  +L    P  +         FC G       +  +AY         ++  ++ R++   TP F I +++    +    K+++ ++                    K +    +++  +L ++ +Q  ++ ++   S   F++++ E      + + D  QL++ +  +T  +DSF G M  MA ++L + RPI+ HPHYED  LR +    Y +Y+KK  K V  +L+      Y+I E + C  + N  GC   ++ DI D SN G +P
Sbjct:   34 FLGSFCIIAGFLNYAHTSY-MQENNVMFSHLSNLERELSFRTEMGFYYSFYKQVIKTFGFGNSLKVLMKDNITEYPDTINSLQRFNVYPELFVGVLYKYFIAITRDLGISTRTCYMVNRGDLPSVQSCEGLGEPAIFYVNIIMLINGFMMSFFFLLGYFVSDKTFLGGLITCASYFFNHRECTRVQWTPPLRESFSYPFLVIQQFFLMFILKNNSYNEVS-IMTKIGFVLSTLMSLLSWQFAQFALLTQCVAIFIAYLIAGTPAKKVITQNVYILLLIVGFANLLLQFGNTLLLAGPLTPCIIMAWVIIGMEPISLSGLRNSILAPLRWIILIISLILSTVLLKYIIGKVLQIKSDD-HMFDILRSKFTNFTS--FDSLLYTCAPEFDFYDMSS-VSQLNSTGL--------LPLA-LCSMLIILFYTMFKWLQLLLKRPDDNSLNQLTDSGFC-GINDFYLFFQTIAYS--------IMAGLIMRLKLFATPQFCIMAALMCKPKWPLIKLSEFLI-------------------VKCMKPSGSHISQKLAKYIQQWPIVLILAICSMAGFNNLKNEWSIQGSYSNWDQEQLMNHVISNTKYSDSFTGQMATMATLRLATGRPIIIHPHYEDEELRKRVHLAYSVYSKKSIKEVWLLLRSTLGAKYLIYEHAHCQMRQNKAGCSYLEMWDIEDPSNAGKVP 692          

Query:   19 FISSVTLIVINLGYCFYIYSTRESNFWWSNISDVEKLISFRTEQGLYYSYYQEFIDQEYILNSFYVLYRNNLTEYPNVINVINRMNIWQEIFLGFLYKIVGKFYERIS-------------------------PIEFYVNXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXVALFTLNRHAMSRVVYLLPLRENFALPFWWIHVLTFHLLIRSTKPSALSQKFIRYIFYMSTLLFCLQWQFGQFVILLESGVIFALNMFEFVSHAD--ARCYYWTCLISLLGTSAMQMGNLMLLSS-FTVAMLISSLILGSYK-TPEMMHSSFSGRLTWLSMQSTGRXXXXXXXXXXSTWILLQNDDSHIFQFLAVKFGIGSSRNFDVNLYNCHEGFGWMPIEKFLISLNMVAYPSFIVYICLGLALLISALSVLWHDTXXXXXL---HPSIHESIVGAGGDFCSGCGHLLSNYPELAYHFGVSSAMLVLTLMVQRMQYLFTPYFVIYSSMFYSNRVVYDKIAKKIVDLSFIYYQPPVNIDSSDNYKKTLVSHRTNLISQLMEWSRQAIVIALICKISFEAFHHIRTELKDLREFYDPDTVQLISWIKHSTSPTDSFAGSMQLMAAVKLISKRPIVNHPHYEDFNLRFKTQKLYQMYAKKDAKYVARILKQ-YKVSYIILEDSICLAKSN--GC---QLKDIIDLSN-GHIP 2004
            F+ S  +I   L Y    Y  +E+N  +S++S++E+ +SFRTE G YYS+Y++ I      NS  VL ++N+TEYP+ IN + R N++ E+F+G LYK        +                          P  FYVN ++L+    +S  F+L     + + LGG+++ A +  N    +RV +  PLRE+F+ PF  I       ++++   + +S    +  F +STL+  L WQF QF +L +   IF   +           +  Y   LI       +Q GN +LL+   T  ++++ +I+G    +   + +S    L W+ +  +  L   L+   +   + +++DD H+F  L  KF   +S  FD  LY C   F +  +   +  LN            L LA L S L +L++   +  +L    P  +         FC      ++++    Y F  + A  ++  ++ R++   TP F I +++    +    K+++ ++                    K +    +++  +L ++ +Q  ++ ++   S   F++++ E      + + D  QL++ +  +T  +DSF G M  MA ++L + RPI+ HPHYED  LR +    Y +Y+KK  K V  +L+      Y+I E + C  + N  GC   ++ DI D SN G +P
Sbjct:   21 FLGSFCIIAGFLNYAHTSY-MQENNVMFSHLSNLERELSFRTEMGFYYSFYKQVIKTFGFGNSLKVLMKDNITEYPDTINSLQRFNVYPELFVGVLYKYFIAITRDLGISTRTCYMVNRGDLPSVQSCEGLGEPAIFYVNIIMLINGFMMSFFFLLGYFVSDKTFLGGLITCASYFFNHRECTRVQWTPPLRESFSYPFLVIQQFFLMFILKNNSYNEVS-IMTKIGFVLSTLMSLLSWQFAQFALLTQCVAIFIAYLIAGTPAKKVITQNVYILLLIVGFANLLLQFGNTLLLAGPLTPCIIMAWVIIGMEPISLSGLRNSILAPLRWIILIISLILSTVLLKYIIGKVLQIKSDD-HMFDILRSKFTNFTS--FDSLLYTCAPEFDFYDMSS-VSQLNSTGL--------LPLA-LCSMLIILFYTMFKWLQLLLKRPDDNSLNQLTDSGFCG-----INDF----YLFFQTIAYSIMAGLIMRLKLFATPQFCIMAALMCKPKWPLIKLSEFLI-------------------VKCMKPSGSHISQKLAKYIQQWPIVLILAICSMAGFNNLKNEWSIQGSYSNWDQEQLMNHVISNTKYSDSFTGQMATMATLRLATGRPIIIHPHYEDEELRKRVHLAYSVYSKKSIKEVWLLLRSTLGAKYLIYEHAHCQMRQNKAGCSYLEMWDIEDPSNAGKVP 679