Intermediate filament 1
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Overview
Neoblast Clusters
Zeng et. al., 2018
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppEmbryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031632 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Intermediate filament 1 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 115.161 bits (287), Expect = 5.300e-26 Identity = 127/533 (23.83%), Postives = 252/533 (47.28%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ--KAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS-----IKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIEL-SSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNR--TTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D++ LN++LA YI++VR LE +N ++ ++ ++ +K Y E+ + +K L K R + + +L + E + KA++ + + K E ++ +KR + E H + ++ KL + ++ L ++ ++ ++ E LQ +E++F K I+ +L E + L D K + +++ L+ A+Q++++ ++D+++ + +E Y ++ +NA+ E NS +E ++ + S +++ L+ ++ + E L DL +S +RD L + K +E+ E + + + + + LLD KL+L +EI AYRKLLEGEE R S G +S+ +Q + V KK + +T ++S+F++ T G V++ E +G+ + L N + + + I R + LL + P K + + + IWA G + ++ + WG G+ + T L N+ GEE A
Sbjct: 28 RLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRG--QVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQRE--FESRLADALQELRAQHEDQVEQYKKELEKTYSAKL-----DNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDL-EDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSH----SSQTQGGGSVTKKRKLEST------ESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQ-NGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVA 539
BLAST of Intermediate filament 1 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 114.39 bits (285), Expect = 7.478e-26 Identity = 127/533 (23.83%), Postives = 252/533 (47.28%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ--KAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS-----IKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIEL-SSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNR--TTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D++ LN++LA YI++VR LE +N ++ ++ ++ +K Y E+ + +K L K R + + +L + E + KA++ + + K E ++ +KR + E H + ++ KL + ++ L ++ ++ ++ E LQ +E++F K I+ +L E + L D K + +++ L+ A+Q++++ ++D+++ + +E Y ++ +NA+ E NS +E ++ + S +++ L+ ++ + E L DL +S +RD L + K +E+ E + + + + + LLD KL+L +EI AYRKLLEGEE R S G +S+ +Q + V KK + +T ++S+F++ T G V++ E +G+ + L N + + + I R + LL + P K + + + IWA G + ++ + WG G+ + T L N+ GEE A
Sbjct: 28 RLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRG--QVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQRE--FESRLADALQELRAQHEDQVEQYKKELEKTYSAKL-----DNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDL-EDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSH----SSQTQGGGSVTKKRKLEST------ESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQ-NGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVA 539
BLAST of Intermediate filament 1 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 113.62 bits (283), Expect = 1.188e-25 Identity = 127/533 (23.83%), Postives = 252/533 (47.28%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ--KAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS-----IKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIEL-SSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNR--TTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D++ LN++LA YI++VR LE +N ++ ++ ++ +K Y E+ + +K L K R + + +L + E + KA++ + + K E ++ +KR + E H + ++ KL + ++ L ++ ++ ++ E LQ +E++F K I+ +L E + L D K + +++ L+ A+Q++++ ++D+++ + +E Y ++ +NA+ E NS +E ++ + S +++ L+ ++ + E L DL +S +RD L + K +E+ E + + + + + LLD KL+L +EI AYRKLLEGEE R S G +S+ +Q + V KK + +T ++S+F++ T G V++ E +G+ + L N + + + I R + LL + P K + + + IWA G + ++ + WG G+ + T L N+ GEE A
Sbjct: 28 RLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRG--QVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQRE--FESRLADALQELRAQHEDQVEQYKKELEKTYSAKL-----DNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDL-EDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSH----SSQTQGGGSVTKKRKLEST------ESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQ-NGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVA 539
BLAST of Intermediate filament 1 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 112.849 bits (281), Expect = 2.623e-25 Identity = 125/530 (23.58%), Postives = 250/530 (47.17%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ--KAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS-----IKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIEL-SSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNR--TTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGE 1834
R ++K D++ LN++LA YI++VR LE +N ++ ++ ++ +K Y E+ + +K L K R + + +L + E + KA++ + + K E ++ +KR + E H + ++ KL + ++ L ++ ++ ++ E LQ +E++F K I+ +L E + L D K + +++ L+ A+Q++++ ++D+++ + +E Y ++ +NA+ E NS +E ++ + S +++ L+ ++ + E L DL +S +RD L + K +E+ E + + + + + LLD KL+L +EI AYRKLLEGEE R S G +S+ +Q + V KK + +T ++S+F++ T G V++ E +G+ + L N + + + I R + LL + P K + + + IWA G + ++ + WG G+ + T L N+ GE
Sbjct: 28 RLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRG--QVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQRE--FESRLADALQELRAQHEDQVEQYKKELEKTYSAKL-----DNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDL-EDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSH----SSQTQGGGSVTKKRKLEST------ESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQ-NGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGE 536
BLAST of Intermediate filament 1 vs. Ensembl Human
Match: LMNB1 (lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637]) HSP 1 Score: 107.457 bits (267), Expect = 1.077e-23 Identity = 148/580 (25.52%), Postives = 277/580 (47.76%), Query Frame = 2
Query: 188 TNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDL--INLEHE---LQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSML--KKRL-GKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERA----------LVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETR--WTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPETN-WGMGSDIHTILYNAVGEERA 1843
T VP ++ R+ T + P++ + R ++K ++R LN++LA YI++VR LE +N +++ ++ G++ +K Y E+ + ++ L + + R K + +L EH+ L AK E D+ +K E S++ AL + L KK L G LE+ K +I +L + ++ L ++T+ +++E Q +++EF K +++ ++NE + L D+ + + +K L+ A+ +++ +D ++++ + +E Y ++ ENA+L E+N+ + R E +R RI L +++ +L++ L DL + ++N R L+ K +E+ E + + + LLD KL+L +EI+AYRKLLEGEE R + S+ V + + +++T + +K+V + A+ +S + + T GNV I E DG+ I L+N + + + + R I G + + + + +T+ IWA G DL N WG G D+ IL N+ GEE A
Sbjct: 3 TATPVPPRMGSRAGGPTTPLSPTRLS-----------RLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKE----SDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKD----QIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYK--LAQALHEMREQHDAQVRLYKEELEQTYHAKL-----ENARLSSEMNTSTVNSAR--EELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRM---LTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGK-------RKRVDVEESEASSSVSISHSASAT--GNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKI--GDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVA 540
BLAST of Intermediate filament 1 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 282.722 bits (722), Expect = 1.063e-86 Identity = 193/577 (33.45%), Postives = 324/577 (56.15%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGN-----YKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE-ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI--PETNWGMGSDIHTILYNAVGEERATY 1849
S S R + RT V SQ R T + + G + RE++K +M +LN++LA YIE+VRFLEAQN+K + +L L+ KWGKDT ++ Y E+ + +KL+ E K R E L ++ EL + + +L + + KI+ LS EA IS+LK+R+ +LE+ + K E +L E+Q + DL+ +T+ ++ + ++Q L+E++FL+++H ++ EL LA RDTT +N++F+K ELS A++DI+ +YD + R+ +ES Y +++Q+ +T++A+ ME K+E KR++ + R ++ DLE++ LE+ + +L ++ E+++R YE L+ + ++ + ++L+ LLD K +L EIA YRK+LEGEE R + LK V Q VK I Q+ ET GE +++ +F R+ KGNVSI E + DG+ I+L+N + K+E I + + R ID R+ + + +P+ + KT+KI+A+ D + E ++G G+++ TIL+N GEERAT+
Sbjct: 4 TSTTPSARAPLGGRTTGNVTSQ--DRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENR-----------------AGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENV-YTLPRDFVLRAGKTLKIFARNQGVASPPDQLVYDAEDSFGSGNNVQTILFNKEGEERATH 560
BLAST of Intermediate filament 1 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 282.722 bits (722), Expect = 1.063e-86 Identity = 193/577 (33.45%), Postives = 324/577 (56.15%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGN-----YKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE-ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI--PETNWGMGSDIHTILYNAVGEERATY 1849
S S R + RT V SQ R T + + G + RE++K +M +LN++LA YIE+VRFLEAQN+K + +L L+ KWGKDT ++ Y E+ + +KL+ E K R E L ++ EL + + +L + + KI+ LS EA IS+LK+R+ +LE+ + K E +L E+Q + DL+ +T+ ++ + ++Q L+E++FL+++H ++ EL LA RDTT +N++F+K ELS A++DI+ +YD + R+ +ES Y +++Q+ +T++A+ ME K+E KR++ + R ++ DLE++ LE+ + +L ++ E+++R YE L+ + ++ + ++L+ LLD K +L EIA YRK+LEGEE R + LK V Q VK I Q+ ET GE +++ +F R+ KGNVSI E + DG+ I+L+N + K+E I + + R ID R+ + + +P+ + KT+KI+A+ D + E ++G G+++ TIL+N GEERAT+
Sbjct: 4 TSTTPSARAPLGGRTTGNVTSQ--DRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENR-----------------AGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENV-YTLPRDFVLRAGKTLKIFARNQGVASPPDQLVYDAEDSFGSGNNVQTILFNKEGEERATH 560
BLAST of Intermediate filament 1 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 282.722 bits (722), Expect = 1.063e-86 Identity = 193/577 (33.45%), Postives = 324/577 (56.15%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGN-----YKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE-ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI--PETNWGMGSDIHTILYNAVGEERATY 1849
S S R + RT V SQ R T + + G + RE++K +M +LN++LA YIE+VRFLEAQN+K + +L L+ KWGKDT ++ Y E+ + +KL+ E K R E L ++ EL + + +L + + KI+ LS EA IS+LK+R+ +LE+ + K E +L E+Q + DL+ +T+ ++ + ++Q L+E++FL+++H ++ EL LA RDTT +N++F+K ELS A++DI+ +YD + R+ +ES Y +++Q+ +T++A+ ME K+E KR++ + R ++ DLE++ LE+ + +L ++ E+++R YE L+ + ++ + ++L+ LLD K +L EIA YRK+LEGEE R + LK V Q VK I Q+ ET GE +++ +F R+ KGNVSI E + DG+ I+L+N + K+E I + + R ID R+ + + +P+ + KT+KI+A+ D + E ++G G+++ TIL+N GEERAT+
Sbjct: 4 TSTTPSARAPLGGRTTGNVTSQ--DRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENR-----------------AGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENV-YTLPRDFVLRAGKTLKIFARNQGVASPPDQLVYDAEDSFGSGNNVQTILFNKEGEERATH 560
BLAST of Intermediate filament 1 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 283.108 bits (723), Expect = 1.185e-86 Identity = 193/577 (33.45%), Postives = 324/577 (56.15%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGN-----YKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE-ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI--PETNWGMGSDIHTILYNAVGEERATY 1849
S S R + RT V SQ R T + + G + RE++K +M +LN++LA YIE+VRFLEAQN+K + +L L+ KWGKDT ++ Y E+ + +KL+ E K R E L ++ EL + + +L + + KI+ LS EA IS+LK+R+ +LE+ + K E +L E+Q + DL+ +T+ ++ + ++Q L+E++FL+++H ++ EL LA RDTT +N++F+K ELS A++DI+ +YD + R+ +ES Y +++Q+ +T++A+ ME K+E KR++ + R ++ DLE++ LE+ + +L ++ E+++R YE L+ + ++ + ++L+ LLD K +L EIA YRK+LEGEE R + LK V Q VK I Q+ ET GE +++ +F R+ KGNVSI E + DG+ I+L+N + K+E I + + R ID R+ + + +P+ + KT+KI+A+ D + E ++G G+++ TIL+N GEERAT+
Sbjct: 12 TSTTPSARAPLGGRTTGNVTSQ--DRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENR-----------------AGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENV-YTLPRDFVLRAGKTLKIFARNQGVASPPDQLVYDAEDSFGSGNNVQTILFNKEGEERATH 568
BLAST of Intermediate filament 1 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 282.722 bits (722), Expect = 1.462e-86 Identity = 193/577 (33.45%), Postives = 324/577 (56.15%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGN-----YKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE-ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI--PETNWGMGSDIHTILYNAVGEERATY 1849
S S R + RT V SQ R T + + G + RE++K +M +LN++LA YIE+VRFLEAQN+K + +L L+ KWGKDT ++ Y E+ + +KL+ E K R E L ++ EL + + +L + + KI+ LS EA IS+LK+R+ +LE+ + K E +L E+Q + DL+ +T+ ++ + ++Q L+E++FL+++H ++ EL LA RDTT +N++F+K ELS A++DI+ +YD + R+ +ES Y +++Q+ +T++A+ ME K+E KR++ + R ++ DLE++ LE+ + +L ++ E+++R YE L+ + ++ + ++L+ LLD K +L EIA YRK+LEGEE R + LK V Q VK I Q+ ET GE +++ +F R+ KGNVSI E + DG+ I+L+N + K+E I + + R ID R+ + + +P+ + KT+KI+A+ D + E ++G G+++ TIL+N GEERAT+
Sbjct: 12 TSTTPSARAPLGGRTTGNVTSQ--DRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENR-----------------AGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENV-YTLPRDFVLRAGKTLKIFARNQGVASPPDQLVYDAEDSFGSGNNVQTILFNKEGEERATH 568
BLAST of Intermediate filament 1 vs. Ensembl Fly
Match: Lam (gene:FBgn0002525 transcript:FBtr0346460) HSP 1 Score: 116.701 bits (291), Expect = 5.749e-27 Identity = 137/538 (25.46%), Postives = 255/538 (47.40%), Query Frame = 2
Query: 266 AYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNE---LSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDL--RHESEENKRDYEIELSSKTKELTEADSIIHETEI--QLK---TLLDDKLSLQLEIAAYRKLLEGEETRW--TDKSSTVVVHE-NGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPV--GTNDLEIPETNWGMGSDIHTILYNAVGE 1834
A + + R +K +++NLN++LA YI++VR LE +N + + E+ +D ++T +K + E+ ++LL + ++R + E D+ L E ++ K++L+ + + E + +E + KL E + E+ +LR + + +++L +T+ +++E +Q +E+ F QIH ++NE + Y + + A+L ++Q++++ Y++++Q+ R I+S Y ++Q + A+ + +K I+ E STR RI L I LE+A DL R E + D + E + +L E + I E+ QLK L+D K+SL LEIAAY KLL GEE R T ++T V + +L ++ + ++ V++K + S + A + + KGNV I E +G+ + L N G + I + R I+ + + ++ N I +W+ K + L + W + TIL N+ GE
Sbjct: 40 ASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAAR------TSNSTHKSIE-ELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSV-ADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVSADNTRTILLNSEGE 569
BLAST of Intermediate filament 1 vs. Ensembl Fly
Match: Lam (gene:FBgn0002525 transcript:FBtr0307059) HSP 1 Score: 116.701 bits (291), Expect = 5.749e-27 Identity = 137/538 (25.46%), Postives = 255/538 (47.40%), Query Frame = 2
Query: 266 AYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNE---LSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDL--RHESEENKRDYEIELSSKTKELTEADSIIHETEI--QLK---TLLDDKLSLQLEIAAYRKLLEGEETRW--TDKSSTVVVHE-NGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPV--GTNDLEIPETNWGMGSDIHTILYNAVGE 1834
A + + R +K +++NLN++LA YI++VR LE +N + + E+ +D ++T +K + E+ ++LL + ++R + E D+ L E ++ K++L+ + + E + +E + KL E + E+ +LR + + +++L +T+ +++E +Q +E+ F QIH ++NE + Y + + A+L ++Q++++ Y++++Q+ R I+S Y ++Q + A+ + +K I+ E STR RI L I LE+A DL R E + D + E + +L E + I E+ QLK L+D K+SL LEIAAY KLL GEE R T ++T V + +L ++ + ++ V++K + S + A + + KGNV I E +G+ + L N G + I + R I+ + + ++ N I +W+ K + L + W + TIL N+ GE
Sbjct: 40 ASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAAR------TSNSTHKSIE-ELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSV-ADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVSADNTRTILLNSEGE 569
BLAST of Intermediate filament 1 vs. Ensembl Fly
Match: Lam (gene:FBgn0002525 transcript:FBtr0307058) HSP 1 Score: 116.701 bits (291), Expect = 5.749e-27 Identity = 137/538 (25.46%), Postives = 255/538 (47.40%), Query Frame = 2
Query: 266 AYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNE---LSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDL--RHESEENKRDYEIELSSKTKELTEADSIIHETEI--QLK---TLLDDKLSLQLEIAAYRKLLEGEETRW--TDKSSTVVVHE-NGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPV--GTNDLEIPETNWGMGSDIHTILYNAVGE 1834
A + + R +K +++NLN++LA YI++VR LE +N + + E+ +D ++T +K + E+ ++LL + ++R + E D+ L E ++ K++L+ + + E + +E + KL E + E+ +LR + + +++L +T+ +++E +Q +E+ F QIH ++NE + Y + + A+L ++Q++++ Y++++Q+ R I+S Y ++Q + A+ + +K I+ E STR RI L I LE+A DL R E + D + E + +L E + I E+ QLK L+D K+SL LEIAAY KLL GEE R T ++T V + +L ++ + ++ V++K + S + A + + KGNV I E +G+ + L N G + I + R I+ + + ++ N I +W+ K + L + W + TIL N+ GE
Sbjct: 40 ASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAAR------TSNSTHKSIE-ELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSV-ADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVSADNTRTILLNSEGE 569
BLAST of Intermediate filament 1 vs. Ensembl Fly
Match: Lam (gene:FBgn0002525 transcript:FBtr0079100) HSP 1 Score: 116.701 bits (291), Expect = 5.749e-27 Identity = 137/538 (25.46%), Postives = 255/538 (47.40%), Query Frame = 2
Query: 266 AYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNE---LSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDL--RHESEENKRDYEIELSSKTKELTEADSIIHETEI--QLK---TLLDDKLSLQLEIAAYRKLLEGEETRW--TDKSSTVVVHE-NGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPV--GTNDLEIPETNWGMGSDIHTILYNAVGE 1834
A + + R +K +++NLN++LA YI++VR LE +N + + E+ +D ++T +K + E+ ++LL + ++R + E D+ L E ++ K++L+ + + E + +E + KL E + E+ +LR + + +++L +T+ +++E +Q +E+ F QIH ++NE + Y + + A+L ++Q++++ Y++++Q+ R I+S Y ++Q + A+ + +K I+ E STR RI L I LE+A DL R E + D + E + +L E + I E+ QLK L+D K+SL LEIAAY KLL GEE R T ++T V + +L ++ + ++ V++K + S + A + + KGNV I E +G+ + L N G + I + R I+ + + ++ N I +W+ K + L + W + TIL N+ GE
Sbjct: 40 ASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAAR------TSNSTHKSIE-ELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSV-ADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVSADNTRTILLNSEGE 569
BLAST of Intermediate filament 1 vs. Ensembl Fly
Match: LamC (gene:FBgn0010397 transcript:FBtr0087512) HSP 1 Score: 106.686 bits (265), Expect = 1.140e-23 Identity = 137/566 (24.20%), Postives = 260/566 (45.94%), Query Frame = 2
Query: 254 SKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELN-LSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDF---WKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLE--RALVDLRHESEENKRDYEIE-----LSSKTKELTEA-DSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKS--------------------TFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
S+ A + R+++K ++++LN++LA YI+++R LE +N + + EL+ +D ++T +K Y E+ +KLL E K + K E D+ L E K L+ +++ L R K E+ + +E +LR ++ +L++ L +T+ +++E + Q +E+ F Q+H +L E + + ++ + ++A+L ++Q+++ Y+ ++++ R IE Y +Q+ K A + +++ E R+ R++I L K+ +LE A ++ R EN D E + ++S EL D + H+ + + + L+D K+SL LEIAAY KLL GEE R +S ++G ++SN + + SAT IS S + N KG++ I+E +GR I L N G + ++ + R G + L F + + + G ++ IW+ G N+L + + W + + + ++L NA E+ A+Y
Sbjct: 28 SRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADR-KKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAA-ANRAAQGSALATEEVRL------MRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQ-EYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSG-ISSNGSHLTASASSRS--GRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTRIA--GDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNL-VMKKKWPVANSMRSVLANADKEDVASY 578
BLAST of Intermediate filament 1 vs. Ensembl Zebrafish
Match: lmnl3 (lamin L3 [Source:ZFIN;Acc:ZDB-GENE-020424-4]) HSP 1 Score: 108.612 bits (270), Expect = 3.319e-24 Identity = 134/565 (23.72%), Postives = 260/565 (46.02%), Query Frame = 2
Query: 200 VPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLL--TEAEKNRGKTEFDLINLEHELQKAKD-----ELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGF--KPVGTNDLEIP-ETNWGMGSDIHTILYNAVGEERATY 1849
V S ++RS + R A+ V + R ++K D+R LN++LA YIE+VR LEA L ++ ++ V+ Y E+ + +K L T E+ R + EF + +H A++ EL + D L + E + + L+ + +L K ++ L +Q L+ LN++ ++ ++ E ++Q ++++F K + + ++ E+ S L D + K+F + +L+ AM+ ++ +++ +I+ + +E + ++++ K K S K+E K S +I +L+ +++ LE +++L+ E ++ + +LS + +E+ + E + + LLD KL L +EI AYRK+LEGEE R N +L+ +T ++Q +KK + T + + + + + + +G VSI E DGR I L+N + +S + + ++ F P M+ + +WA + +DL + +WG +D+ L N EE A Y
Sbjct: 4 VTSTPMERSASAAVRASRRSGASPCTVSPTRLTRLQEKEDLRQLNDRLANYIERVRQLEADKSSMQILLEEKEESSLREVGNVRRLYESELADARKSLDATANERARLQIEFSQLQEDHRKLAARNNKKECELTAAVDRWRNLEVALNAKEADFANLLSTNRRLETEISEL-------KTQVPALEAALQKLKTQLNSEMLRRVDAENQIQTLQEQLDFQKHLGEQEVREMRSRHESRLLELDCGR-QKEF-EGKLAEAMKQLRDEHETQIRQYKDELEKTFNAKLENAKQTAVKNSDFAFSTKEELAGTKLRLESQTQQINNLQKQVVCLEARVLELQQTLEHERQVSQQKLSQQQQEMAALRLQMQEQLEEYENLLDVKLMLDMEINAYRKMLEGEEKRL-----------NQSLSPIQQTLSPIIQQS---RKKRKHDATCSGFSPNYRLSQHSSCRGPVSIEEVDLDGRYIKLKNASDRDQVVSGWQLRKSEAEAPDIV-FCFPSPCVMNAGHMLTVWAAAAVDQCGSASDLLLSTHQSWGSFADVRVSLLNIQNEEMAEY 544
BLAST of Intermediate filament 1 vs. Ensembl Zebrafish
Match: lmnl3 (lamin L3 [Source:ZFIN;Acc:ZDB-GENE-020424-4]) HSP 1 Score: 107.842 bits (268), Expect = 4.802e-24 Identity = 134/565 (23.72%), Postives = 260/565 (46.02%), Query Frame = 2
Query: 200 VPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLL--TEAEKNRGKTEFDLINLEHELQKAKD-----ELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGF--KPVGTNDLEIP-ETNWGMGSDIHTILYNAVGEERATY 1849
V S ++RS + R A+ V + R ++K D+R LN++LA YIE+VR LEA L ++ ++ V+ Y E+ + +K L T E+ R + EF + +H A++ EL + D L + E + + L+ + +L K ++ L +Q L+ LN++ ++ ++ E ++Q ++++F K + + ++ E+ S L D + K+F + +L+ AM+ ++ +++ +I+ + +E + ++++ K K S K+E K S +I +L+ +++ LE +++L+ E ++ + +LS + +E+ + E + + LLD KL L +EI AYRK+LEGEE R N +L+ +T ++Q +KK + T + + + + + + +G VSI E DGR I L+N + +S + + ++ F P M+ + +WA + +DL + +WG +D+ L N EE A Y
Sbjct: 4 VTSTPMERSASAAVRASRRSGASPCTVSPTRLTRLQEKEDLRQLNDRLANYIERVRQLEADKSSMQILLEEKEESSLREVGNVRRLYESELADARKSLDATANERARLQIEFSQLQEDHRKLAARNNKKECELTAAVDRWRNLEVALNAKEADFANLLSTNRRLETEISEL-------KTQVPALEAALQKLKTQLNSEMLRRVDAENQIQTLQEQLDFQKHLGEQEVREMRSRHESRLLELDCGR-QKEF-EGKLAEAMKQLRDEHETQIRQYKDELEKTFNAKLENAKQTAVKNSDFAFSTKEELAGTKLRLESQTQQINNLQKQVVCLEARVLELQQTLEHERQVSQQKLSQQQQEMAALRLQMQEQLEEYENLLDVKLMLDMEINAYRKMLEGEEKRL-----------NQSLSPIQQTLSPIIQQS---RKKRKHDATCSGFSPNYRLSQHSSCRGPVSIEEVDLDGRYIKLKNASDRDQVVSGWQLRKSEAEAPDIV-FCFPSPCVMNAGHMLTVWAAAAVDQCGSASDLLLSTHQSWGSFADVRVSLLNIQNEEMAEY 544
BLAST of Intermediate filament 1 vs. Ensembl Zebrafish
Match: lmnb2 (lamin B2 [Source:ZFIN;Acc:ZDB-GENE-990630-13]) HSP 1 Score: 107.842 bits (268), Expect = 5.319e-24 Identity = 138/560 (24.64%), Postives = 269/560 (48.04%), Query Frame = 2
Query: 251 PSK-SAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ------KAKD-ELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEH--KAKDKMEILKLRDEIQNLQR-DLNNQTIKYLNVECELQGKL--DEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRI---KNEWGSTRSRIPDLENKIISLERALVDLRHESEE------NKRD-YEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW---TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEI-PETNWGMGSDIHTILYNAVGEERA 1843
PS+ SAA + + R ++K ++R LN++LA YI++VR LE +N + ++S ++ ++ +K Y E+ + +++L E + R K + +L + EL+ K KD +L + +L + E L+ + + L L L+ KA+D + K + E++ L R DL N+ + L E E + + +E+ ++ H+ ++ E+ + +D ++ +LS A+QD++ +++++Q+ + ++ + ++ +NAK+ +LN +K + + E RI L ++ +L++ E + RD Y +L +K +E+ E + + + + LLD KL+L +EI AYRKLLEGEE R SS V V +++ + ++ K++ + E S+T + + G+VSI E +G+ + L N + + + R I G +++ PK G +T+ +W+ G +DL +++WG G +I T+L N+ GE+ A
Sbjct: 6 PSRASAAQTPLSPARISRLQEKEELRALNDRLAVYIDRVRALELENDRLQFKVSEKEEVTTREVSGIKSLYEAELADARRVLDETARERAKLQIELGKVNSELEEVTRNYKKKDGDLAAALVRIKDLEAQYNKNEAALNTALSENASLSAELADLKAQLAKAEDAHGVAKKQLEVETLMRVDLENR-CQSLTEELEFRKSMFDEEVRETRRRHEKRMVEVDSGMQQD--------YEFKLSQALQDLRKQHEEQVQIYKEELQHTFKAKL-----DNAKVSSDLN-----DKAVLTAREELQEAHVRIEGLSYQLSALQKQASAAEERIRELEGLLSSDRDKYRRQLDAKEREMAEMRECMQQQLNEYQELLDVKLALDMEINAYRKLLEGEEDRLKLSPSPSSRVTVSRTTASSTSASSRSSRAKRKRV------ELEESSTAGPKVQISQQAEASGSVSIEEIDLEGKSVTLRNNSDKDQSLGSWRLKRQIGDGEEIVYKFSPKFVLKAG-QTVTVWSADAGMSHSPPSDLLWKSQSSWGTGENILTLLVNSSGEDVA 539
BLAST of Intermediate filament 1 vs. Ensembl Zebrafish
Match: lmna (lamin A [Source:ZFIN;Acc:ZDB-GENE-020424-3]) HSP 1 Score: 107.842 bits (268), Expect = 7.500e-24 Identity = 125/550 (22.73%), Postives = 262/550 (47.64%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINL-----EHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKD-KMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYR----DTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS--IKDENKRIKNEWGSTRSRIPDLENKIISLERALV----DLRHESEENKRDYEI---ELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW-----TDKSSTVVVHE---NGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNR-----TTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D+ NLN++LA YI++VR LE +N ++ + + ++ +K Y E+ + +K L K R + + +L + E + + K E +L + + + + S ++ +KR ++E +D K ++ KL + + ++ L ++ ++ ++ E +Q +E+EF K I+ +L E S Y + + ++++L+ A+ D+++ +++++++ + IE Y ++K ENA+ E NS + ++ ++ TR R+ + +++ L++ L +R E R+ +I L K KE+ E + + + + LLD KL+L +EI+AYRKLLEGEE R + V V +G+ T +++ ++ + ++++ + ++ A+ + T R + G V++ E +G+ + L N + + + R I G ++ + P K + +T+ IWA G + ++ + +WG G T L ++ GEE A
Sbjct: 25 RLQEKEDLSNLNDRLAVYIDKVRSLEVENAGLRMRITESETEISRELSGMKAAYEAELADARKTLDSVAKERARLQLELSKVREDYKELKARNGKKEADLESALARLKDLESLLNSKDASLST---ALGEKRTLEVE---VRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYSEELRE-SKRRYESRVVEIDSGRQQDYESKLADALTDLRNQHEEQLRIYKEEIEKTY-----NSKLENARSSAERNSHLVGAAHEELQQ----TRVRMEGVSSQLSQLQKQLAAREAKIRELEEALSRERDILRRRLEDKEKEMAEMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPARGVTVTRSSGSGSHTRVVQSSTSRTSSGSAKKRRLNDNDSDASSVVGGTVTRTRISQQASASGRVTVDEVDLEGKFVRLNNKSDQDQSLGHWQVKRQIGSGTPIV-YKFPPKFNLKAGQTVTIWAAGAGGTHSPPSDLVWKTQNSWGSGDLFQTTLISSSGEEMA 557
BLAST of Intermediate filament 1 vs. Ensembl Zebrafish
Match: lmna (lamin A [Source:ZFIN;Acc:ZDB-GENE-020424-3]) HSP 1 Score: 107.842 bits (268), Expect = 7.500e-24 Identity = 125/550 (22.73%), Postives = 262/550 (47.64%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINL-----EHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKD-KMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYR----DTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS--IKDENKRIKNEWGSTRSRIPDLENKIISLERALV----DLRHESEENKRDYEI---ELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW-----TDKSSTVVVHE---NGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNR-----TTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D+ NLN++LA YI++VR LE +N ++ + + ++ +K Y E+ + +K L K R + + +L + E + + K E +L + + + + S ++ +KR ++E +D K ++ KL + + ++ L ++ ++ ++ E +Q +E+EF K I+ +L E S Y + + ++++L+ A+ D+++ +++++++ + IE Y ++K ENA+ E NS + ++ ++ TR R+ + +++ L++ L +R E R+ +I L K KE+ E + + + + LLD KL+L +EI+AYRKLLEGEE R + V V +G+ T +++ ++ + ++++ + ++ A+ + T R + G V++ E +G+ + L N + + + R I G ++ + P K + +T+ IWA G + ++ + +WG G T L ++ GEE A
Sbjct: 25 RLQEKEDLSNLNDRLAVYIDKVRSLEVENAGLRMRITESETEISRELSGMKAAYEAELADARKTLDSVAKERARLQLELSKVREDYKELKARNGKKEADLESALARLKDLESLLNSKDASLST---ALGEKRTLEVE---VRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYSEELRE-SKRRYESRVVEIDSGRQQDYESKLADALTDLRNQHEEQLRIYKEEIEKTY-----NSKLENARSSAERNSHLVGAAHEELQQ----TRVRMEGVSSQLSQLQKQLAAREAKIRELEEALSRERDILRRRLEDKEKEMAEMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPARGVTVTRSSGSGSHTRVVQSSTSRTSSGSAKKRRLNDNDSDASSVVGGTVTRTRISQQASASGRVTVDEVDLEGKFVRLNNKSDQDQSLGHWQVKRQIGSGTPIV-YKFPPKFNLKAGQTVTIWAAGAGGTHSPPSDLVWKTQNSWGSGDLFQTTLISSSGEEMA 557
BLAST of Intermediate filament 1 vs. Ensembl Xenopus
Match: lmx1a (LIM homeobox transcription factor 1 alpha [Source:Xenbase;Acc:XB-GENE-481569]) HSP 1 Score: 107.457 bits (267), Expect = 1.077e-23 Identity = 131/559 (23.43%), Postives = 268/559 (47.94%), Query Frame = 2
Query: 239 TRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNR-------GKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTK------DNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKII-------SLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGR-QLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
+R SAA + R ++K D+R+LN++LA YIE+VR LEA +L ++ ++ +++ Y E+ + +KLL + R GK D L+ K + +L+L++++ +L K+ E L+ + L + G LEE + + +I L +++ + L+++ + +++E ++Q ++++F + IH+ ++ E+ R T+ + ++++L+ A+Q+++ D++ +I + +E + ++ ENA+L NS D + E +T+ R+ L +++ +LE + +L+ + + +++ K +E+TE + + + LLD KL+L +EI AYRK+LEGEE R S +++ + +++ K ++K++ET S T + K ++ G VS+ + +G + L N + + ++ R HG + + +P + + + + IWA G V + ++ NWG G DI IL ++ GEE A
Sbjct: 7 SRAREHASAAPSPGSPTRISRMQEKEDLRHLNDRLAAYIERVRSLEADKSLLKIQLEEKEEVTSREVTNLRLLYETELADARKLLDQTANERARLQVELGKVREDYRQLQARNSKKETDLSLAQNLLRDLESKLNTKEADLA------TALSGKRG-LEEQLQEQRAQIAGLESSLRDTTKQLHDEMLWRVDLENKMQTIKEQLDFQRNIHEQEVKEMRK---RHDTRIVEIDSGRRIEFESKLAEALQELRRDHEQQISDYKEQLERNFSAKL-----ENAQLAAAKNS--DYASATREEIMATKLRVDTLSSQLSQYQKQNSALEAKVRELQDMLDRAHDMHRRQMTEKDREVTEIRQTLQAQLEEYEQLLDVKLALDMEINAYRKMLEGEEQRLKLSPSPSQRSTVSRASTSQSSRLSRGK-----KRKLEETGRSVTKR-AYKVVQEASSTGPVSVEDIDPEGNYVRLLNNTEEDHSLHGWVVRR--KHGSLPEIAYKLPCRFVLKSEQRVTIWAAGAGAVHSPPTDLVWKSHKNWGTG-DIKIILLDSSGEECA 539
BLAST of Intermediate filament 1 vs. Ensembl Xenopus
Match: lmx1a (LIM homeobox transcription factor 1 alpha [Source:Xenbase;Acc:XB-GENE-481569]) HSP 1 Score: 107.071 bits (266), Expect = 1.382e-23 Identity = 131/559 (23.43%), Postives = 268/559 (47.94%), Query Frame = 2
Query: 239 TRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNR-------GKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTK------DNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKII-------SLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGR-QLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
+R SAA + R ++K D+R+LN++LA YIE+VR LEA +L ++ ++ +++ Y E+ + +KLL + R GK D L+ K + +L+L++++ +L K+ E L+ + L + G LEE + + +I L +++ + L+++ + +++E ++Q ++++F + IH+ ++ E+ R T+ + ++++L+ A+Q+++ D++ +I + +E + ++ ENA+L NS D + E +T+ R+ L +++ +LE + +L+ + + +++ K +E+TE + + + LLD KL+L +EI AYRK+LEGEE R S +++ + +++ K ++K++ET S T + K ++ G VS+ + +G + L N + + ++ R HG + + +P + + + + IWA G V + ++ NWG G DI IL ++ GEE A
Sbjct: 7 SRAREHASAAPSPGSPTRISRMQEKEDLRHLNDRLAAYIERVRSLEADKSLLKIQLEEKEEVTSREVTNLRLLYETELADARKLLDQTANERARLQVELGKVREDYRQLQARNSKKETDLSLAQNLLRDLESKLNTKEADLA------TALSGKRG-LEEQLQEQRAQIAGLESSLRDTTKQLHDEMLWRVDLENKMQTIKEQLDFQRNIHEQEVKEMRK---RHDTRIVEIDSGRRIEFESKLAEALQELRRDHEQQISDYKEQLERNFSAKL-----ENAQLAAAKNS--DYASATREEIMATKLRVDTLSSQLSQYQKQNSALEAKVRELQDMLDRAHDMHRRQMTEKDREVTEIRQTLQAQLEEYEQLLDVKLALDMEINAYRKMLEGEEQRLKLSPSPSQRSTVSRASTSQSSRLSRGK-----KRKLEETGRSVTKR-AYKVVQEASSTGPVSVEDIDPEGNYVRLLNNTEEDHSLHGWVVRR--KHGSLPEIAYKLPCRFVLKSEQRVTIWAAGAGAVHSPPTDLVWKSHKNWGTG-DIKIILLDSSGEECA 539
BLAST of Intermediate filament 1 vs. Ensembl Xenopus
Match: lmx1a (LIM homeobox transcription factor 1 alpha [Source:Xenbase;Acc:XB-GENE-481569]) HSP 1 Score: 106.301 bits (264), Expect = 2.122e-23 Identity = 130/559 (23.26%), Postives = 267/559 (47.76%), Query Frame = 2
Query: 239 TRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNR-------GKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTK------DNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKII-------SLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGR-QLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
+R SAA + R ++K D+R+LN++LA YIE+VR LEA +L ++ ++ +++ Y E+ + +KLL + R GK D L+ K + +L+L++++ +L K+ E L+ + L + G LEE + + +I L +++ + L+++ + +++E ++Q ++++F + IH+ ++ E+ R T+ + ++++L+ A+Q+++ D++ +I + +E + ++ ENA+L NS D + E +T+ R+ L +++ +LE + +L+ + + +++ K +E+TE + + + LLD KL+L +EI AYRK+LEGEE R S +++ + +++ K ++K++ET S T + K ++ G VS+ + +G + L N + + ++ R HG + + +P + + + + IWA G V + ++ NWG G DI IL ++ GE R
Sbjct: 7 SRAREHASAAPSPGSPTRISRMQEKEDLRHLNDRLAAYIERVRSLEADKSLLKIQLEEKEEVTSREVTNLRLLYETELADARKLLDQTANERARLQVELGKVREDYRQLQARNSKKETDLSLAQNLLRDLESKLNTKEADLA------TALSGKRG-LEEQLQEQRAQIAGLESSLRDTTKQLHDEMLWRVDLENKMQTIKEQLDFQRNIHEQEVKEMRK---RHDTRIVEIDSGRRIEFESKLAEALQELRRDHEQQISDYKEQLERNFSAKL-----ENAQLAAAKNS--DYASATREEIMATKLRVDTLSSQLSQYQKQNSALEAKVRELQDMLDRAHDMHRRQMTEKDREVTEIRQTLQAQLEEYEQLLDVKLALDMEINAYRKMLEGEEQRLKLSPSPSQRSTVSRASTSQSSRLSRGK-----KRKLEETGRSVTKR-AYKVVQEASSTGPVSVEDIDPEGNYVRLLNNTEEDHSLHGWVVRR--KHGSLPEIAYKLPCRFVLKSEQRVTIWAAGAGAVHSPPTDLVWKSHKNWGTG-DIKIILLDSSGEVRC 539
BLAST of Intermediate filament 1 vs. Ensembl Xenopus
Match: rnasek (ribonuclease K [Source:Xenbase;Acc:XB-GENE-6046202]) HSP 1 Score: 103.605 bits (257), Expect = 1.672e-22 Identity = 132/535 (24.67%), Postives = 257/535 (48.04%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDL--INLEHE-----LQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLER-----ALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPETN-WGMGSDIHTILYNAVGEERA 1843
R ++K D++ LN++LA YI++VR LE++N +++ ++ ++ +K Y E+ + ++ L + + R + + +L I++EHE K + EL ++ E + L+ ++ L+ G++E+ KA EI +L + ++ L + + +++E Q ++E++F K +++ ++ E + L D+ K + ++ +LS A+ D++ +D ++ + + +E Y +K ENA+L E+NS + R E +R RI L +++ L++ L D+ + ++N R L+ + +E+ + + + + LLD KL+L +EI+AYRKLLEGEE R S +T + + V+ +K++ + A+ +S + + T G+VSI E DG+ I L+N + + + R I G + F + + +T+ IWA G +DL N W G D+ IL N+ GE+ A
Sbjct: 18 RLQEKVDLQELNDRLAVYIDKVRSLESENSLLHVQVTEREEVRSREVSGIKELYETELADARRSLDDTARERARLQLELSKISVEHEDLRASFSKKESELESAQARFRETEALLNSKNAALATTQSENKSLQ---GEVEDLKA----EIGQLESALALAKKQLEEEILIKVDLENRCQSLIEELDFRKNVYEEEIKETRRRHETRLVEVDSGKQIE--YEHKLSQALADMREQHDSQVTLYKEELEHTY-----QSKLENARLSSEMNSSAVNSTR--EELMESRYRIDSLTSQLSELQKEVKISKLEDMLAKEKDNSRKM---LAEREREMADIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSP-----PSRVTVSRASSSRSVRTAKGKRKRIDVEESEASSSVSISHSASAT--GDVSIEEVDVDGKYIRLKNNSEQDHPLGGWELTRTI--GEASVNFKFTSRYVLKAGQTVTIWAADAGVTASPPSDLIWKNQNSWATGEDVKVILKNSQGEDVA 524
BLAST of Intermediate filament 1 vs. Ensembl Xenopus
Match: rnasek (ribonuclease K [Source:Xenbase;Acc:XB-GENE-6046202]) HSP 1 Score: 102.064 bits (253), Expect = 5.423e-22 Identity = 132/540 (24.44%), Postives = 257/540 (47.59%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDL--INLEHE-----LQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERA----------LVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPETN-WGMGSDIHTILYNAVGEERA 1843
R ++K D++ LN++LA YI++VR LE++N +++ ++ ++ +K Y E+ + ++ L + + R + + +L I++EHE K + EL ++ E + L+ ++ L+ G++E+ KA EI +L + ++ L + + +++E Q ++E++F K +++ ++ E + L D+ K + ++ +LS A+ D++ +D ++ + + +E Y +K ENA+L E+NS + R E +R RI L +++ L++ L D+ + ++N R L+ + +E+ + + + + LLD KL+L +EI+AYRKLLEGEE R S +T + + V+ +K++ + A+ +S + + T G+VSI E DG+ I L+N + + + R I G + F + + +T+ IWA G +DL N W G D+ IL N+ GE+ A
Sbjct: 37 RLQEKVDLQELNDRLAVYIDKVRSLESENSLLHVQVTEREEVRSREVSGIKELYETELADARRSLDDTARERARLQLELSKISVEHEDLRASFSKKESELESAQARFRETEALLNSKNAALATTQSENKSLQ---GEVEDLKA----EIGQLESALALAKKQLEEEILIKVDLENRCQSLIEELDFRKNVYEEEIKETRRRHETRLVEVDSGKQIE--YEHKLSQALADMREQHDSQVTLYKEELEHTY-----QSKLENARLSSEMNSSAVNSTR--EELMESRYRIDSLTSQLSELQKESRAWHDRMQELEDMLAKEKDNSRKM---LAEREREMADIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSP-----PSRVTVSRASSSRSVRTAKGKRKRIDVEESEASSSVSISHSASAT--GDVSIEEVDVDGKYIRLKNNSEQDHPLGGWELTRTI--GEASVNFKFTSRYVLKAGQTVTIWAADAGVTASPPSDLIWKNQNSWATGEDVKVILKNSQGEDVA 548
BLAST of Intermediate filament 1 vs. Ensembl Mouse
Match: Lmnb2 (lamin B2 [Source:MGI Symbol;Acc:MGI:96796]) HSP 1 Score: 125.176 bits (313), Expect = 1.505e-29 Identity = 138/559 (24.69%), Postives = 266/559 (47.58%), Query Frame = 2
Query: 248 IPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKA-KDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSA-----LAYRDTTKDNK-DFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLER---ALVDLRHESEE---NKRD-YEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW---TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSAT----GEISAKSTFNRTT--KGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERAT 1846
+P + + + R ++K ++R LN++LA YI++VR LE +N + +S ++ ++ +K Y E+ + +++L E + R + + ++ ++ EL++A K ++ + ++ E L + L + G LE A+ + ++ K D ++ L +T+ +++E Q +E+ F K + + ++ E L D+++ + DF +++ A++D++S +D+++++ R +E Y K +NAKLL + N R E R R+ L +++ L++ A + HE EE +RD + L +K +E+TE + + + + LLD KL+L +EI+AYRKLLEGEE R SS + + + +S+ V Q +++++ +TS + +S+ S + T G V+I E +GR + L+N + + + I R + G + PK G +T+ +WA G + + +TNWG G T L +A GEE A
Sbjct: 4 LPPHAGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQG-LETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDF---KMAQALEDLRSQHDEQVRLYRVELEQTY-----QAKLDNAKLLSDQNDKAAHAAR--EELKEARMRVESLSYQLLGLQKQASAAENHIHELEEALAGERDKFRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDMEISAYRKLLEGEEERLKLSPSPSSRITISRATSSSSSSSGVGMSVGQGRGKRRRLETEDTSGSPSRASRVSSGSRLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKRQVLEGEDIAYKFTPKYVLRAG-QTVTVWAAGAGATHSPPSTLVWKSQTNWGPGESFRTALVSADGEEVAV 550
BLAST of Intermediate filament 1 vs. Ensembl Mouse
Match: Lmnb2 (lamin B2 [Source:MGI Symbol;Acc:MGI:96796]) HSP 1 Score: 124.79 bits (312), Expect = 1.929e-29 Identity = 138/559 (24.69%), Postives = 266/559 (47.58%), Query Frame = 2
Query: 248 IPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKA-KDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSA-----LAYRDTTKDNK-DFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLER---ALVDLRHESEE---NKRD-YEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW---TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSAT----GEISAKSTFNRTT--KGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERAT 1846
+P + + + R ++K ++R LN++LA YI++VR LE +N + +S ++ ++ +K Y E+ + +++L E + R + + ++ ++ EL++A K ++ + ++ E L + L + G LE A+ + ++ K D ++ L +T+ +++E Q +E+ F K + + ++ E L D+++ + DF +++ A++D++S +D+++++ R +E Y K +NAKLL + N R E R R+ L +++ L++ A + HE EE +RD + L +K +E+TE + + + + LLD KL+L +EI+AYRKLLEGEE R SS + + + +S+ V Q +++++ +TS + +S+ S + T G V+I E +GR + L+N + + + I R + G + PK G +T+ +WA G + + +TNWG G T L +A GEE A
Sbjct: 23 LPPHAGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQG-LETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDF---KMAQALEDLRSQHDEQVRLYRVELEQTY-----QAKLDNAKLLSDQNDKAAHAAR--EELKEARMRVESLSYQLLGLQKQASAAENHIHELEEALAGERDKFRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDMEISAYRKLLEGEEERLKLSPSPSSRITISRATSSSSSSSGVGMSVGQGRGKRRRLETEDTSGSPSRASRVSSGSRLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKRQVLEGEDIAYKFTPKYVLRAG-QTVTVWAAGAGATHSPPSTLVWKSQTNWGPGESFRTALVSADGEEVAV 569
BLAST of Intermediate filament 1 vs. Ensembl Mouse
Match: Lmnb1 (lamin B1 [Source:MGI Symbol;Acc:MGI:96795]) HSP 1 Score: 106.686 bits (265), Expect = 1.402e-23 Identity = 139/554 (25.09%), Postives = 264/554 (47.65%), Query Frame = 2
Query: 260 SAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDL--INLEHE---LQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRL-GKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERA----------LVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETR--WTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPETN-WGMGSDIHTILYNAVGEERA 1843
SA + + R ++K ++R LN++LA YI++VR LE +N +++ ++ G++ +K Y E+ + ++ L + + R K + +L EH+ L AK E +LS + + + + AL KK L G LE+ K +I +L + ++ L ++T+ +++E Q +++EF K +++ ++NE + L D+ + + +K L+ A+ +++ +D ++++ + +E Y ++ ENA+L E+N+ + R E +R RI L +++ +L++ L D+ + +N R LS + +E+ E + + + LLD KL+L +EI+AYRKLLEGEE R + S+ V + + +++T + +K+V + A+ +S + + T GNV I E DG+ I L+N + + + + R I G + + + + +T+ +WA G DL N WG G D+ IL N+ GEE A
Sbjct: 17 SAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGD--KKSLEGDLEDLKD----QIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYK--LAQALHEMREQHDAQVRLYKEELEQTYHAKL-----ENARLSSEMNTSTVNSAR--EELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRM---LSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGK-------RKRVDVEESEASSSVSISHSASAT--GNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKI--GDTSVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVA 541
BLAST of Intermediate filament 1 vs. Ensembl Mouse
Match: Lmna (lamin A [Source:MGI Symbol;Acc:MGI:96794]) HSP 1 Score: 106.301 bits (264), Expect = 2.564e-23 Identity = 122/531 (22.98%), Postives = 249/531 (46.89%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ--KAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS-----IKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIEL-SSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D++ LN++LA YI++VR LE +N ++ ++ ++ +K Y E+ + +K L K R + + +L + E + KA++ + + K E ++ +KR + E H + ++ KL + ++ L ++ ++ ++ E LQ +E++F K I+ +L E + L D K + +++ L+ A+Q++++ ++D+++ + +E Y ++ +NA+ E NS +E ++ + S +++ L+ ++ + E L DL +S +RD L + K +E+ E + + + + + LLD KL+L +EI AYRKLLEGEE R S G ++ + +Q ++K++ + + ++ A+ T G V++ E +G+ + L N + + + I R + L+ + P K + + + IWA G + ++ + WG GS + T L N+ GEE A
Sbjct: 28 RLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRG--QVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQRE--FESRLADALQELRAQHEDQVEQYKKELEKTYSAKL-----DNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDL-EDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRG--RASSHSSQSQGGGSVTKKRKLESSESRSSFSQHAR------TSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQ-NGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINSTGEEVA 539
BLAST of Intermediate filament 1 vs. Ensembl Mouse
Match: Lmna (lamin A [Source:MGI Symbol;Acc:MGI:96794]) HSP 1 Score: 105.145 bits (261), Expect = 3.570e-23 Identity = 122/531 (22.98%), Postives = 249/531 (46.89%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ--KAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNS-----IKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIEL-SSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI---PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D++ LN++LA YI++VR LE +N ++ ++ ++ +K Y E+ + +K L K R + + +L + E + KA++ + + K E ++ +KR + E H + ++ KL + ++ L ++ ++ ++ E LQ +E++F K I+ +L E + L D K + +++ L+ A+Q++++ ++D+++ + +E Y ++ +NA+ E NS +E ++ + S +++ L+ ++ + E L DL +S +RD L + K +E+ E + + + + + LLD KL+L +EI AYRKLLEGEE R S G ++ + +Q ++K++ + + ++ A+ T G V++ E +G+ + L N + + + I R + L+ + P K + + + IWA G + ++ + WG GS + T L N+ GEE A
Sbjct: 28 RLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRG--QVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQRE--FESRLADALQELRAQHEDQVEQYKKELEKTYSAKL-----DNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDL-EDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRG--RASSHSSQSQGGGSVTKKRKLESSESRSSFSQHAR------TSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQ-NGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINSTGEEVA 539
BLAST of Intermediate filament 1 vs. UniProt/SwissProt
Match: sp|Q01241|NF70_DORPE (70 kDa neurofilament protein OS=Doryteuthis pealeii OX=1051067 PE=2 SV=1) HSP 1 Score: 301.597 bits (771), Expect = 3.254e-92 Identity = 204/550 (37.09%), Postives = 313/550 (56.91%), Query Frame = 2
Query: 227 FNYETRVIPSKSAAYGDVG--NYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELT----EADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSST-VVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETN--WGMGSDIHTILYNAVGEERATY 1849
F+Y +P + A G + K RE++K DMR+LNE+ A YIE+VRFLEAQNKK +GEL LK KWGK+T +K Y E++ +KL+ K + + + L +L++ + +L SR ++I ++L++ E ISML++ + LE+ K + + K+ DE++ ++ DLNN+TI +L+ E Q +E+EF K +H +L EL+ALAYRDTT +N++FW+ EL+ A++DIQ +YD + +R IE+ Y +++Q+ +T K ME+ K+EN ++K+ R+R+ DLE + LER DL + EE R E+E +E+T E +SI+ E L+ L+D KLSL+LEIAAYRKLLEGEE+R K VV L T + + + Q + GE++AK+T+ RT+KG+VSI E + G I LE K +E ++ I R +D + + + IP G +KIW+K + D + N WG GS++ TIL N GE++A Y
Sbjct: 67 FSYGATAMPGRYANISSTGVNHVKANREREKQDMRDLNERFANYIEKVRFLEAQNKKLAGELEELKSKWGKETSAIKEMYETELEEARKLIDATNKEKITLDVRVTELIDQLERQQKDLEESRTYHQIDQEQIARQNQQLADLEGEISMLRRSIESLEKEKMRQSNILAKMNDEMEKMRMDLNNETINHLDAENRRQTLEEELEFQKDVHAQELKELAALAYRDTTAENREFWRNELAQAIRDIQQEYDAKCDQMRGDIEAYYNLKVQEFRTGATKQNMEVTRNKEENTKLKSNMTEIRNRLADLEARNAQLERTNQDLLRDLEEKDRQNELESCQYKEEITKLRGEMESILKE----LQDLMDIKLSLELEIAAYRKLLEGEESRVGMKQIVEQVVGARPNEAEVLSTILTRSEGGYEATGDSQISMKMMRGELAAKTTYQRTSKGSVSIKEADSQGCFIALET--KKEENLTGWKIVRKVDDNK-VYTYEIPNLVLKTGT-VVKIWSKNHQAQARGDDLVSRENDTWGTGSNVVTILQNEKGEDKANY 608
BLAST of Intermediate filament 1 vs. UniProt/SwissProt
Match: sp|P90901|IFA1_CAEEL (Intermediate filament protein ifa-1 OS=Caenorhabditis elegans OX=6239 GN=ifa-1 PE=1 SV=2) HSP 1 Score: 282.722 bits (722), Expect = 1.860e-85 Identity = 193/577 (33.45%), Postives = 324/577 (56.15%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGN-----YKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE-ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEI--PETNWGMGSDIHTILYNAVGEERATY 1849
S S R + RT V SQ R T + + G + RE++K +M +LN++LA YIE+VRFLEAQN+K + +L L+ KWGKDT ++ Y E+ + +KL+ E K R E L ++ EL + + +L + + KI+ LS EA IS+LK+R+ +LE+ + K E +L E+Q + DL+ +T+ ++ + ++Q L+E++FL+++H ++ EL LA RDTT +N++F+K ELS A++DI+ +YD + R+ +ES Y +++Q+ +T++A+ ME K+E KR++ + R ++ DLE++ LE+ + +L ++ E+++R YE L+ + ++ + ++L+ LLD K +L EIA YRK+LEGEE R + LK V Q VK I Q+ ET GE +++ +F R+ KGNVSI E + DG+ I+L+N + K+E I + + R ID R+ + + +P+ + KT+KI+A+ D + E ++G G+++ TIL+N GEERAT+
Sbjct: 12 TSTTPSARAPLGGRTTGNVTSQ--DRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENR-----------------AGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENV-YTLPRDFVLRAGKTLKIFARNQGVASPPDQLVYDAEDSFGSGNNVQTILFNKEGEERATH 568
BLAST of Intermediate filament 1 vs. UniProt/SwissProt
Match: sp|P90900|IFA4_CAEEL (Intermediate filament protein ifa-4 OS=Caenorhabditis elegans OX=6239 GN=ifa-4 PE=1 SV=3) HSP 1 Score: 263.462 bits (672), Expect = 3.430e-78 Identity = 172/526 (32.70%), Postives = 310/526 (58.94%), Query Frame = 2
Query: 290 KKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEI---QLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIP--ETNWGMGSDIHTILYNAVGEERATY 1849
++ R ++K +M LN++LA YIE+VRFLEAQN+K +L+ L+ KWG D+ VK+ Y E+++ K L+ +++K R + E + L EL +++L+ + + K+++ +L EA I +LK+R+ +EE K E ++ D + + + + +T+ ++ + ++Q L+E +F+++IH +++++L A+A RDTT +N++++K ELS A+++I+S+YD R+ IES Y +++Q+ T+N++ +E N ++E KR++ G R ++ DLE + + LE+ + DL ++ EE+ R YE L+ K T + + E++I +L+ L+D K +L EI YRK+L+GEE R + L+ V Q VK +I Q K E+ GE ++ S+++R+ KGN++I E G+ I+LENI + E I D + R I R+++ F P++ + K++KI+A+G D + E ++G G+D+ T LYN GE+RA++
Sbjct: 64 RESRTREKKEMSELNDRLASYIEKVRFLEAQNRKMEKDLNLLRGKWGHDSTSVKVMYETELRSAKDLIADSDKERAQLEDQIKKLVEELNNYRNKLHEAERGADVTRKELDNVLGRLGALEAEIELLKRRISLMEESIGHLKRENHRMIDSLHHARNAVEQETLNRIDYQNQVQTLLEECDFIRRIHDSEIHDLLAMASRDTTVENREYFKNELSSAIREIRSEYDHVSNTTRTDIESWYKLKVQEIHTQNSRNCLEQNYAREEVKRLRTTLGDMRGKMADLEGRNLLLEKQIEDLNYQMEEDMRSYEQSLNDKD---TSINKLRDESKILMVELQMLIDTKQTLDAEIVIYRKMLDGEENR-----------------AGLRQLVEQVVKTTSIHQTKEIESLRVLKGETTSHSSYSRSAKGNIAIQEAEPSGKYIVLENISRRDENIGDWKLRRKIAGKREIV-FTFPREFTLRAQKSVKIFARGQGVHSPPDSLVYDLEDSFGTGNDVVTTLYNKEGEDRASH 568
BLAST of Intermediate filament 1 vs. UniProt/SwissProt
Match: sp|P23730|IFEA_ASCSU (Intermediate filament protein A (Fragment) OS=Ascaris suum OX=6253 PE=1 SV=1) HSP 1 Score: 250.751 bits (639), Expect = 2.940e-74 Identity = 175/523 (33.46%), Postives = 305/523 (58.32%), Query Frame = 2
Query: 320 MRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXS-------MLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQ-LKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQ-VKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE-ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIP---ETNWGMGSDIHTILYNAVGEERATY 1849
M +LN++LA YIE+VRFLEAQN+K + +L L+ +WGKDT V+ Y E+Q +KL+ + NR + E LE E++K DEL+ R + L+ +I +++ E +S +L++R+ + E A+ K E L+ +E+ + DL+ +T+ ++ + ++Q L+E++F++++H ++ EL A+A RDTT +N++++K EL+ A++DI+++YD + R +ES Y +++Q+ +T++ + +E N K KR++ + R ++ DLE + SL + +L ++ E+++R YE L+ + ++ + D E Q L LLD K +L EIA YRK+LEGEE R + L+ V Q VK + Q E+ GE +++++F R+ KGNVSI E DGR ++LEN ++KEE I + + R ID R+++ + +P+ + K++KIWA+G + + ++ E +G GS++ TIL+N GEERAT+
Sbjct: 1 MSDLNDRLASYIEKVRFLEAQNRKLAADLDLLRGRWGKDTLSVRAMYEGELQEARKLVNDT--NRQREE-----LEKEIRKLLDELSEYRRKYEDALRGHQIDRDRIDELLNQLSGLEAEINLLRRRIANIIEEIARIKKENLQFANELTKARSDLDQETLNRIDFQNQVQTLLEEIDFMRRVHDQEIAELQAMASRDTTPENREYFKNELASAIRDIRAEYDQICNVNRMDMESWYKLKVQEIQTQSTRQNLEQNYAK---KRLRVQLTDLRGKLADLEGR-NSLLKQTQELNYQLEDDQRSYEAALNDRDAQIRKMDE-----ECQALMMLLDTKQTLDAEIAIYRKMLEGEENR-----------------AGLRQLVEQVVKTHGLTQVDETESLRVLKGETASRTSFQRSAKGNVSIQETAPDGRYVVLENTHRSKEEAIGEWKLKRKIDGKREIV-YTLPRDFILRPGKSVKIWARGQGGIHSPPEQLVFDLEDTFGSGSNVQTILFNREGEERATH 489
BLAST of Intermediate filament 1 vs. UniProt/SwissProt
Match: sp|Q01240|NF60_DORPE (60 kDa neurofilament protein OS=Doryteuthis pealeii OX=1051067 PE=2 SV=1) HSP 1 Score: 249.21 bits (635), Expect = 1.529e-73 Identity = 155/386 (40.16%), Postives = 238/386 (61.66%), Query Frame = 2
Query: 227 FNYETRVIPSKSAAYGDVG--NYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELT----EADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETR 1366
F+Y +P + A G + K RE++K DMR+LNE+ A YIE+VRFLEAQNKK +GEL LK KWGK+T +K Y E++ +KL+ K + + + L +L++ + +L SR ++I ++L++ E ISML++ + LE+ K + + K+ DE++ ++ DLNN+TI +L+ E Q +E+EF K +H +L EL+ALAYRDTT +N++FW+ EL+ A++DIQ +YD + +R IE+ Y +++Q+ +T K ME+ K+EN ++K+ R+R+ DLE + LER DL + EE R E+E +E+T E +SI+ E L+ L+D KLSL+LEIAAYRKLLEGEE+R
Sbjct: 67 FSYGATAMPGRYANISSTGVNHVKANREREKQDMRDLNERFANYIEKVRFLEAQNKKLAGELEELKSKWGKETSAIKEMYETELEEARKLIDATNKEKITLDVRVTELIDQLERQQKDLEESRTYHQIDQEQIARQNQQLADLEGEISMLRRSIESLEKEKMRQSNILAKMNDEMEKMRMDLNNETINHLDAENRRQTLEEELEFQKDVHAQELKELAALAYRDTTAENREFWRNELAQAIRDIQQEYDAKCDQMRGDIEAYYNLKVQEFRTGATKQNMEVTRNKEENTKLKSNMTEIRNRLADLEARNAQLERTNQDLLRDLEEKDRQNELESCQYKEEITKLRGEMESILKE----LQDLMDIKLSLELEIAAYRKLLEGEESR 448
BLAST of Intermediate filament 1 vs. TrEMBL
Match: A0A1Z1R173 (Intermediate filament 1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1155.2 bits (2987), Expect = 0.000e+0 Identity = 596/596 (100.00%), Postives = 596/596 (100.00%), Query Frame = 2
Query: 62 IIREKSNSTVSLKTMTENNQIENSKEKTVSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
IIREKSNSTVSLKTMTENNQIENSKEKTVSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMENELLKKIEICEEKLSEEEALISMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY
Sbjct: 1 IIREKSNSTVSLKTMTENNQIENSKEKTVSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMENELLKKIEICEEKLSEEEALISMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 596
BLAST of Intermediate filament 1 vs. TrEMBL
Match: Q86M45 (Intermediate filament protein OS=Dugesia japonica OX=6161 GN=Djf-2 PE=2 SV=1) HSP 1 Score: 870.152 bits (2247), Expect = 0.000e+0 Identity = 446/614 (72.64%), Postives = 537/614 (87.46%), Query Frame = 2
Query: 32 MQKTVTQNSTIIREKSNSTVSLKTMTENNQI--------ENSKEKTVSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
MQKTVTQN+TIIREKS+S VSLK E NQI EN +++++SPI++QRTIIINRTN+Q II +SF Y++ + P S G++GN+K++REKDK DMRNLNEKLAGYIEQVRFLEAQNKKQ EL+NLK+KWGK+TEEVK Y+ E++NL+ LL +AEKNRGK +FDL NL+++LQ+AK+EL++SR+ ENEL K++E CEE+LSEEEALISMLKKR+ L+E K +D+ EIL LRDEIQNLQ DLNNQTIKYLN ECELQGKLDE+EFLKQIHQ QLNELSALAYRDTTKDNKDFWKAE++LAMQDIQSDYDDRIQMLRSSIESQ GV+MQD K+ENAK MELN+ K+ENKRIKN+W S++S++PDLENKII LER LVD+R E EENKRDYE+E+S+KTKEL +AD +I + +++LKTLLDDKLSLQLEIAAYRKLLEGEETRWT+K++TVVVHENG+L ++LKTF+NQ+++E+IV+KK+QETNT +TGEISAKSTFNRTTKGN SILEC+TDG+CI LENIGK KE++SDM INRDIDHGRQL KF++PKKT +D +KT+KIWAKGFKP GTNDLEI ETNWG+GSDIHT L +A GEE+ATY
Sbjct: 1 MQKTVTQNTTIIREKSSSNVSLKKGGELNQIDLSSENMKENVQKRSLSPIATQRTIIINRTNSQPSHTIINKSFAYDSMLSPINSNVSGEIGNFKRDREKDKKDMRNLNEKLAGYIEQVRFLEAQNKKQGEELTNLKEKWGKETEEVKNMYSNELKNLQILLIDAEKNRGKMDFDLNNLQNDLQRAKEELDISRNFENELRKQLEKCEEELSEEEALISMLKKRIANLDEQKLRDRKEILNLRDEIQNLQTDLNNQTIKYLNSECELQGKLDEIEFLKQIHQAQLNELSALAYRDTTKDNKDFWKAEIALAMQDIQSDYDDRIQMLRSSIESQNGVKMQDIKSENAKFYMELNATKEENKRIKNDWNSSKSKMPDLENKIIVLERTLVDVRQELEENKRDYEMEISNKTKELADADFLIQDIQMKLKTLLDDKLSLQLEIAAYRKLLEGEETRWTEKNNTVVVHENGSLNNSLKTFINQIQEESIVKKKIQETNTMSTGEISAKSTFNRTTKGNCSILECSTDGKCITLENIGKLKEDMSDMTINRDIDHGRQLTKFMLPKKTILDPSKTLKIWAKGFKPSGTNDLEILETNWGIGSDIHTTLLSATGEEKATY 614
BLAST of Intermediate filament 1 vs. TrEMBL
Match: A0A5J6BTN2 (Intermediate filament b-like protein 1 (Fragment) OS=Minona ileanae OX=60013 PE=2 SV=1) HSP 1 Score: 427.172 bits (1097), Expect = 5.749e-138 Identity = 238/584 (40.75%), Postives = 387/584 (66.27%), Query Frame = 2
Query: 146 VSPISSQRTIIINRT-----NNQVPSQI----IQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTS----ATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGN---KTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
+ P+++ RT++I RT N S + ++RS + V + + V N + REK+K DMR+LNE+ A YIE+VRFLEAQNKK + EL+ L+D+WGK+TE +K Y++EM L+KLL +A K++ + E + +LE + + + +L+ + + N + I+ ++S++E+ +S+L++R+ E ++DK E+ +LRDEI+ L+ DL+ +T+ ++N E E DE+EFLK++H ++L EL+ALAYRDTT++N++FW++E+S ++DIQ++YD+++ +++S +E+ Y +++Q+++T N + EL K+EN RIK + R RIP+LE + LER L +LR ++EE RD+E+E SS K L++ + + ++L+TLLD KLSL+LEIAAYRKLLEGEE+R ++ +V E +S+ +T I +K S GE+SAK+T+ RT KGN+SI EC DG+ + +EN GK +E+IS M I R++D+GRQ+++F P KTF++ K+IK+WA+G KP G++D+E E WG G++IHT+L ++ GEE+AT+
Sbjct: 34 IKPVATPRTVVITRTAHGGGGNSTGSVVREVEMRRSTGALSSVNGHTAGVHNGVSNIMENREKEKKDMRDLNERFANYIEKVRFLEAQNKKLANELATLRDRWGKETERIKQMYDVEMTQLRKLLDDAMKSKAELEVKVNSLEETVDELQKQLDAANQLHNSDREMIDRLNSQVSDQESELSVLRRRISSFESDHSRDKAEVQRLRDEIRRLRMDLDQETLNHINSEQEAHSLRDEIEFLKKVHDSELKELAALAYRDTTQENREFWRSEMSQCLRDIQNEYDNKLDVMQSEMETHYNLKIQESRTNNTRGGAELQHTKEENIRIKQQLSELRDRIPELEARNAQLERLLEELRRDNEEKLRDWELERSSLRKTLSDNQAELESVLVELQTLLDAKLSLELEIAAYRKLLEGEESRAGLRN---LVEETMKRSSDYET------TRVIETRKTNAMPPSNMGIIKGEMSAKTTYQRTAKGNISIQECAPDGKFLTIENTGKKREDISGMRITRNVDNGRQIIRFTFPDKTFLEPEGRAKSIKVWARGLKPPGSSDMECNENTWGNGANIHTVLISSDGEEKATH 608
BLAST of Intermediate filament 1 vs. TrEMBL
Match: A0A267FSC2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010052g3 PE=3 SV=1) HSP 1 Score: 426.017 bits (1094), Expect = 8.118e-138 Identity = 252/581 (43.37%), Postives = 388/581 (66.78%), Query Frame = 2
Query: 143 TVSPISSQRTIIINRTNNQVPSQIIQRSFNYET----RVIPSKSAAYG------DVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFM-DG-NKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
T PIS+ +T++INRT +P I R ++ RV S ++A G +V N REK+K DM+ LNE+ A YIE+VRFLEAQNKK S EL LKD+WGK+TE VK Y E+ L+KLL ++EK + + E + +LE +L + + L+ + + I+ ++L++ + IS+L++R+ +E +++D+ EI +LRDE+ L+ DL+ +T+ ++N E E Q +++EF+KQIH+++L EL+ALAYRDTT +N++FWK E++ A+ +IQ +YD+++ ++RS IESQY +++Q+ +T N + MEL+ +++ENKRIK + R+RIP+LE + LER L +LR E EE +R+ E+E +L + + E +L+TL+D KLSL+LEIAAYRKLLEGEETR T + + T ++F V+Q+ + Q + ++ + GE+SAK+T+ RT KGNVSI EC+ DG+ I+LEN GK KE+IS + R+ID+GRQ++KF +P + DG +K I+IWA+G KP G++DLE E++WG+G++I+T LYN GEERAT+
Sbjct: 20 TRGPISAPKTVVINRT---LPGFGIGRGDTVDSVKSVRVTRSMASASGIQQTNAEVNNMLNGREKEKKDMQELNERFANYIEKVRFLEAQNKKLSNELQQLKDRWGKETERVKQTYETELAQLRKLLDDSEKQKAEAEVRISSLEDQLNELQVLLDEANRQHQVDRETIDKLNQQLADYDGEISLLRRRVATFDEERSRDRKEIKRLRDEVNRLRGDLDAETLNHINAENEAQSLREQLEFMKQIHESELKELAALAYRDTTSENREFWKNEMAQALHEIQREYDNKMDVMRSEIESQYSMKVQEARTTNTRDNMELSHLREENKRIKGQMTDARNRIPELEARNAQLERELEELRREMEEAERECEMEKGRLRTDLANTQATLEEYLKELQTLMDMKLSLELEIAAYRKLLEGEETRINQHHRTQELMSQKSSTVESRSFA--VEQQAMHQGQNKQQMSLIKGEMSAKTTYQRTAKGNVSIQECSADGKYILLENTGKKKEDISGWRLLRNIDNGRQVIKFTVPNGVVLGDGPHKNIRIWARGLKPPGSDDLEAAESSWGVGANINTSLYNTEGEERATH 595
BLAST of Intermediate filament 1 vs. TrEMBL
Match: W0GAA8 (Intermediate filament b-like protein OS=Macrostomum lignano OX=282301 GN=if1 PE=2 SV=1) HSP 1 Score: 425.631 bits (1093), Expect = 1.171e-137 Identity = 252/581 (43.37%), Postives = 388/581 (66.78%), Query Frame = 2
Query: 143 TVSPISSQRTIIINRTNNQVPSQIIQRSFNYET----RVIPSKSAAYG------DVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFM-DG-NKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
T PIS+ +T++INRT +P I R ++ RV S ++A G +V N REK+K DM+ LNE+ A YIE+VRFLEAQNKK S EL LKD+WGK+TE VK Y E+ L+KLL ++EK + + E + +LE +L + + L+ + + I+ ++L++ + IS+L++R+ +E +++D+ EI +LRDE+ L+ DL+ +T+ ++N E E Q +++EF+KQIH+++L EL+ALAYRDTT +N++FWK E++ A+ +IQ +YD+++ ++RS IESQY +++Q+ +T N + MEL+ +++ENKRIK + R+RIP+LE + LER L +LR E EE +R+ E+E +L + + E +L+TL+D KLSL+LEIAAYRKLLEGEETR T + + T ++F V+Q+ + Q + ++ + GE+SAK+T+ RT KGNVSI EC+ DG+ I+LEN GK KE+IS + R+ID+GRQ++KF +P + DG +K I+IWA+G KP G++DLE E++WG+G++I+T LYN GEERAT+
Sbjct: 20 TRGPISAPKTVVINRT---LPGFGIGRGDTVDSVKSVRVTRSMASASGIQQTNAEVNNMLNGREKEKKDMQELNERFANYIEKVRFLEAQNKKLSNELQQLKDRWGKETERVKQTYETELAQLRKLLDDSEKQKAEAEVRISSLEDQLNELQVLLDEANRQHQVDRETIDKLNQQLADYDGEISLLRRRVATFDEERSRDQKEIKRLRDEVNRLRGDLDAETLNHINAENEAQSLREQLEFMKQIHESELKELAALAYRDTTSENREFWKNEMAQALHEIQREYDNKMDVMRSEIESQYSMKVQEARTTNTRDNMELSHLREENKRIKGQMTDARNRIPELEARNAQLERELEELRREMEEAERECEMEKGRLRTDLANTQATLEEYLKELQTLMDMKLSLELEIAAYRKLLEGEETRINQHHRTQELMSQKSSTVESRSFA--VEQQAMHQGQNKQQMSLIKGEMSAKTTYQRTAKGNVSIQECSADGKYILLENTGKKKEDISGWRLLRNIDNGRQVIKFTVPNGVVLGDGPHKNIRIWARGLKPPGSDDLEAAESSWGVGANINTSLYNTEGEERATH 595
BLAST of Intermediate filament 1 vs. Ensembl Cavefish
Match: lmnb1 (lamin B1 [Source:NCBI gene;Acc:103034386]) HSP 1 Score: 99.3673 bits (246), Expect = 2.200e-21 Identity = 138/544 (25.37%), Postives = 262/544 (48.16%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDL--INLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQI-----------HQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLE-------NKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLK---TLLDDKLSLQLEIAAYRKLLEGEETR--WTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEI-PETNWGMGSDIHTILYNAVGEERAT 1846
R ++K ++ NLN++LA YI++VR LE++N ++S ++ ++ +K Y E+ + ++ L + K R + + +L I EHE Q + D+ + ++ S+E +L + L +R LE A + +I +L + + ++ L ++T+ +++E Q ++E+EF K + H+T+L E+ D+ + + ++ +L+ A+ D++ +DD++++ + +E Y ++++ + + + ++E K S +++ L+ ++I LE AL E + ++R L+ K +E++E I + ++QL+ LLD KL+L +EI AYRKLLEGEE R + S+ V + + +++T + K+ V + E ++S + SA +T GNV I E DG+ I L N + + + R I KF PK G K + IWA G DL +++WG G ++ +L N GEE A
Sbjct: 25 RLQEKEELSNLNDRLAIYIDKVRSLESENSVLHLQISEKEEVRSRELTGLKALYETELADARRSLDDTAKERARLQIELGKIRTEHE-QLLQSYAKKDSDLAGCQARLKDVEALLNSKEASLATALSERKA-LEGSLADLQAQIHELEASLASARKQLGDETLLRVDLENRCQSLVEELEFRKNMFEEEIKDTRRRHETRLVEV------DSGRQVE--YEFKLAQALTDMRQQHDDQVKVYKEEMEQTYMAKLENVRLSSEMNSSSASMAREELKEASLRVESLTAQLSGLQKEARGWQDRINELESALA---QEKDLSRR----MLADKEREISE---IRAKMQLQLEEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKR---VDVEESEASSSVSIAHSASAT------GNVCIDELDVDGKFIRLHNTSDQDQPMVGFEMTRTIGDSSATYKFT-PKYVLKAGQK-VTIWASNAGVSSSPPTDLIWKSQSSWGTGENVKVVLTNGDGEEVAV 537
BLAST of Intermediate filament 1 vs. Ensembl Cavefish
Match: lmnb1 (lamin B1 [Source:NCBI gene;Acc:103034386]) HSP 1 Score: 94.7449 bits (234), Expect = 6.103e-20 Identity = 141/564 (25.00%), Postives = 266/564 (47.16%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDL--INLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQI-----------HQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENA---------------------KLLMELNSIKDENKRIKNEWGSTRS------RIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQL---KTLLDDKLSLQLEIAAYRKLLEGEETR--WTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEI-PETNWGMGSDIHTILYNAVGEERAT 1846
R ++K ++ NLN++LA YI++VR LE++N ++S ++ ++ +K Y E+ + ++ L + K R + + +L I EHE Q + D+ + ++ S+E +L + L +R LE A + +I +L + + ++ L ++T+ +++E Q ++E+EF K + H+T+L E+ D+ + + ++ +L+ A+ D++ +DD++++ + +E Y ++++ + + L +L+ ++ E + N GS+R + +++I LE AL E + ++R L+ K +E++E I + ++QL + LLD KL+L +EI AYRKLLEGEE R + S+ V + + +++T + K+ V + E ++S + SA +T GNV I E DG+ I L N + + + R I KF PK G K + IWA G DL +++WG G ++ +L N GEE A
Sbjct: 25 RLQEKEELSNLNDRLAIYIDKVRSLESENSVLHLQISEKEEVRSRELTGLKALYETELADARRSLDDTAKERARLQIELGKIRTEHE-QLLQSYAKKDSDLAGCQARLKDVEALLNSKEASLATALSERKA-LEGSLADLQAQIHELEASLASARKQLGDETLLRVDLENRCQSLVEELEFRKNMFEEEIKDTRRRHETRLVEV------DSGRQVE--YEFKLAQALTDMRQQHDDQVKVYKEEMEQTYMAKLENVRLSSEMNSSSASMAREELKEASLRVESLTAQLSGLQKEEEETLNR-GSSRGGGECQDQARGWQDRINELESALA---QEKDLSRR----MLADKEREISE---IRAKMQLQLEEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKR---VDVEESEASSSVSIAHSASAT------GNVCIDELDVDGKFIRLHNTSDQDQPMVGFEMTRTIGDSSATYKFT-PKYVLKAGQK-VTIWASNAGVSSSPPTDLIWKSQSSWGTGENVKVVLTNGDGEEVAV 556
BLAST of Intermediate filament 1 vs. Ensembl Cavefish
Match: lmnl3 (lamin-L(III)-like [Source:NCBI gene;Acc:103047028]) HSP 1 Score: 94.3597 bits (233), Expect = 8.875e-20 Identity = 138/549 (25.14%), Postives = 248/549 (45.17%), Query Frame = 2
Query: 278 VGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLL--TEAEKNRGKTEFDLINLEHEL---QKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSA-----LAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQL-------EIAAYRKLLEGEETRW------TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATG-EISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPE-TNWGMGSDIHTILYNAVGEERA 1843
V + R ++K D+R LN++LA YIE+VR LE+ L ++ ++ V++ Y E+ + +K L T E+ R + E+ + +H + K E LS +E + + ++ + R +LE A + + L +QN + +N++T++ ++VE ++Q ++M+F K + + ++ E+ + L D+ + K+F +++L+ AMQ ++ +++ +IQ + +E + ++ ENAK + NS D K E T+ R+ +I +L+ L +E +R + E + L++ D + + Q++T L++ SL EI AYRK+LEGEE R + SS H GT + K K+ E A+G S K + + +++G VSI E G I L N + + ++ R G + F IPK + T+ IW+ G +P DL + WG SD+ L+N EE A
Sbjct: 24 VSPTRLSRLQEKEDLRQLNDRLANYIERVRQLESDKSSMQLLLEEKEETTTRELRSVRLLYENELADARKTLDTTANERARLQIEYSQLCEDHRRLVSRNNKKEAELSNAVERWRSLEAALNSKEADYANL---LAANR--RLETDVADLRTHVDNLESALQNAKTQINSETLRRVDVENQIQTLQEQMDFQKHVTEQEVREMRSRHETRLVEVDSGR-QKEF-ESKLAEAMQQLRQEHEAQIQQYKDDLERTFSAKL-----ENAKQVAVKNS--DFATSTKEELAGTKLRLESQSLQISNLQTQNSTLEARVQELERMLDRERQVSHQRLSQKDQEMADMRQQMQTQLEEYQSLLDLKLMLDMEINAYRKMLEGEEKRLNLSPSPSQHSSISRTHAQGTRKAGSK-------------KRKHE---GASGLSPSYKVSQHSSSRGVVSIDEIDLMGNFIKLRNNSDTDQSLGGWVV-RKRQSGTPDVVFKIPKSCILRAEDTVTIWSAGAGVEPNPPTDLVLSGLKTWGAVSDVLVSLFNTHNEEAA 541
BLAST of Intermediate filament 1 vs. Ensembl Cavefish
Match: lmnl3 (lamin-L(III)-like [Source:NCBI gene;Acc:103047028]) HSP 1 Score: 94.3597 bits (233), Expect = 9.385e-20 Identity = 137/542 (25.28%), Postives = 246/542 (45.39%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLL--TEAEKNRGKTEFDLINLEHEL---QKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSA-----LAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQL-------EIAAYRKLLEGEETRW------TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATG-EISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPE-TNWGMGSDIHTILYNAVGEERA 1843
R ++K D+R LN++LA YIE+VR LE+ L ++ ++ V++ Y E+ + +K L T E+ R + E+ + +H + K E LS +E + + ++ + R +LE A + + L +QN + +N++T++ ++VE ++Q ++M+F K + + ++ E+ + L D+ + K+F +++L+ AMQ ++ +++ +IQ + +E + ++ ENAK + NS D K E T+ R+ +I +L+ L +E +R + E + L++ D + + Q++T L++ SL EI AYRK+LEGEE R + SS H GT + K K+ E A+G S K + + +++G VSI E G I L N + + ++ R G + F IPK + T+ IW+ G +P DL + WG SD+ L+N EE A
Sbjct: 31 RLQEKEDLRQLNDRLANYIERVRQLESDKSSMQLLLEEKEETTTRELRSVRLLYENELADARKTLDTTANERARLQIEYSQLCEDHRRLVSRNNKKEAELSNAVERWRSLEAALNSKEADYANL---LAANR--RLETDVADLRTHVDNLESALQNAKTQINSETLRRVDVENQIQTLQEQMDFQKHVTEQEVREMRSRHETRLVEVDSGR-QKEF-ESKLAEAMQQLRQEHEAQIQQYKDDLERTFSAKL-----ENAKQVAVKNS--DFATSTKEELAGTKLRLESQSLQISNLQTQNSTLEARVQELERMLDRERQVSHQRLSQKDQEMADMRQQMQTQLEEYQSLLDLKLMLDMEINAYRKMLEGEEKRLNLSPSPSQHSSISRTHAQGTRKAGSK-------------KRKHE---GASGLSPSYKVSQHSSSRGVVSIDEIDLMGNFIKLRNNSDTDQSLGGWVV-RKRQSGTPDVVFKIPKSCILRAEDTVTIWSAGAGVEPNPPTDLVLSGLKTWGAVSDVLVSLFNTHNEEAA 541
BLAST of Intermediate filament 1 vs. Ensembl Cavefish
Match: lmnl3 (lamin-L(III)-like [Source:NCBI gene;Acc:103047028]) HSP 1 Score: 94.3597 bits (233), Expect = 9.605e-20 Identity = 138/549 (25.14%), Postives = 248/549 (45.17%), Query Frame = 2
Query: 278 VGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLL--TEAEKNRGKTEFDLINLEHEL---QKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSA-----LAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQL-------EIAAYRKLLEGEETRW------TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATG-EISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPE-TNWGMGSDIHTILYNAVGEERA 1843
V + R ++K D+R LN++LA YIE+VR LE+ L ++ ++ V++ Y E+ + +K L T E+ R + E+ + +H + K E LS +E + + ++ L + +LE A + + L +QN + +N++T++ ++VE ++Q ++M+F K + + ++ E+ + L D+ + K+F +++L+ AMQ ++ +++ +IQ + +E + ++ ENAK + NS D K E T+ R+ +I +L+ L +E +R + E + L++ D + + Q++T L++ SL EI AYRK+LEGEE R + SS H GT + K K+ E A+G S K + + +++G VSI E G I L N + + ++ R G + F IPK + T+ IW+ G +P DL + WG SD+ L+N EE A
Sbjct: 24 VSPTRLSRLQEKEDLRQLNDRLANYIERVRQLESDKSSMQLLLEEKEETTTRELRSVRLLYENELADARKTLDTTANERARLQIEYSQLCEDHRRLVSRNNKKEAELSNAVERWRSLEAALNSKEADYANLLAAN-----RRLETDVADLRTHVDNLESALQNAKTQINSETLRRVDVENQIQTLQEQMDFQKHVTEQEVREMRSRHETRLVEVDSGR-QKEF-ESKLAEAMQQLRQEHEAQIQQYKDDLERTFSAKL-----ENAKQVAVKNS--DFATSTKEELAGTKLRLESQSLQISNLQTQNSTLEARVQELERMLDRERQVSHQRLSQKDQEMADMRQQMQTQLEEYQSLLDLKLMLDMEINAYRKMLEGEEKRLNLSPSPSQHSSISRTHAQGTRKAGSK-------------KRKHE---GASGLSPSYKVSQHSSSRGVVSIDEIDLMGNFIKLRNNSDTDQSLGGWVV-RKRQSGTPDVVFKIPKSCILRAEDTVTIWSAGAGVEPNPPTDLVLSGLKTWGAVSDVLVSLFNTHNEEAA 541
BLAST of Intermediate filament 1 vs. Ensembl Sea Lamprey
Match: lmnb2 (lamin B2 [Source:ZFIN;Acc:ZDB-GENE-990630-13]) HSP 1 Score: 99.7525 bits (247), Expect = 7.050e-23 Identity = 92/348 (26.44%), Postives = 172/348 (49.43%), Query Frame = 2
Query: 848 HQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVD-----------LRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW---TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPE-TNWGMGSDIHTILYNAVGEER 1840
H+++L E+ A ++ ++++L+ A+QD+++++ D++Q+ ++ +E+ Y TK ENAK+ ++ NS + ++ E +R RI L N++ +L+R + LR E + + R +L+ K +ELTE + + + LL+ KL+L +EI+AYRK+LEGEE R SS V V + + ++T ++ VQ+ ++ S T SA G +++ E GR + L N + + + + R I HG + + +T + +I IWA G + DL + + + WG G ++ ++ NA GEE+
Sbjct: 11 HESRLVEIDA--------GHQQEYESKLAQALQDLRAEHMDQVQLYKNELENNY-----KTKMENAKMSLQQNSTM--SGVVQEELTESRMRIETLNNQLGALQRQVAGAEAKIRDLEETLRRERDSHWR----QLADKDRELTEIRQAMTAQINEYEQLLEVKLALDMEISAYRKMLEGEEERLHLSPSPSSRVTVTRS---SETVRTSGGAKRKRLDVQESEATSSVSVTQRASA--------SGVIAVDEIDAGGRFVKLINDSQQDQAVGGWTVKRSI-HGHADIVYKFTGRTIVKAGDSITIWAGGAGVQHNPPRDLLMKQHSTWGSGDEVRVVVLNANGEEQ 327
BLAST of Intermediate filament 1 vs. Ensembl Sea Lamprey
Match: lmnb2 (lamin B2 [Source:ZFIN;Acc:ZDB-GENE-990630-13]) HSP 1 Score: 94.3597 bits (233), Expect = 2.035e-20 Identity = 121/550 (22.00%), Postives = 264/550 (48.00%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELS----------NLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQ-------RDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTT-----KDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLE---RALVD-LRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWT----DKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQ-ETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEI-PETNWGMGSDIHTILYNAVGEERAT 1846
R ++K + LN++LA YIE+VR LE + +S ++ + T ++ Y+ E+ +++ L +A + LE +L+ A+ E + R ++ ++ + ++ + E + + L K + E+ LR+++ L+ + L +T+ +++E + +E+EF K+IH+ +++E + + R+T + ++ +LS A+ +++ +++++Q+ R ++ +++ + K +++ SI+++ + + G+ S++ ++ + L+ R L + L HE +++KR L +EL E ++ E I+ + LLD KL+L +EIAAYRKLLEGEE+R + VV + + + +++T + +K+VQ E + + + + + G++ I E +G+ + + N + + + ++ R I+ + + + + + +T+ IWA G +DL +++WG G DI T L N+ GEE A
Sbjct: 16 RLQEKESLVELNDRLAAYIERVRSLEVDKARLLARVSMWEEEEEEQRQKSERQREATGGLRAAYDAELAEVRRALDDALGAKAA-------LEIQLRLAQVERDEGRSRCSKYEQEWNVALGRIRDMEVQLCAKEASLSTASGDKEYLETEVDDLRNQVNQLEGVLVSSKQQLEEETLARVDLENRMLTLQEELEFTKRIHEQEIHE--SRSKRETHVLEIDGGQQQAFEYKLSEALTELRQQHEEQVQLYRQELDQTMRAKLEKSILTPEKQSLDI-SIREDLREATSRVGTLSSQLSAAQHDLALLQGRVRELEETLSHERDQSKR----RLDESDRELAELREVMDEQLIEYEQLLDIKLALDMEIAAYRKLLEGEESRLNLSPEKGVQSSVVQTSTSASHSIRTMPGK-------RKRVQLEGFVDSMAQSQRSVSQHASASGSIGIKEVDMEGKSVTMVNNSEKDQPLGGWVLKRQIEDQAE-IAYKFSSRYVLKAGQTVTIWAANAGVSHNPPSDLLWKTQSSWGTGDDIRTSLLNSDGEEVAV 543
BLAST of Intermediate filament 1 vs. Ensembl Sea Lamprey
Match: lmnb2 (lamin B2 [Source:ZFIN;Acc:ZDB-GENE-990630-13]) HSP 1 Score: 86.2705 bits (212), Expect = 2.506e-18 Identity = 88/361 (24.38%), Postives = 171/361 (47.37%), Query Frame = 2
Query: 848 HQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVD-----------LRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW---TDKSSTVVVHEN-----------GTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEE--ISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEIPE-TNWGMGSDIHTILYNAVGEER 1840
H+++L E+ A ++ ++++L+ A+QD+++++ D++Q+ ++ +E+ Y TK ENAK+ ++ NS + ++ E +R RI L N++ +L+R + LR E + + R +L+ K +ELTE + + + LL+ KL+L +EI+AYRK+LEGEE R SS V V + G ++ + + + ++ + S T + G +++ E GR + L N + +++ + + R I HG + + +T + +I IWA G + DL + + + WG G ++ ++ NA GEE+
Sbjct: 10 HESRLVEIDA--------GHQQEYESKLAQALQDLRAEHMDQVQLYKNELENNY-----KTKMENAKMSLQQNSTM--SGVVQEELTESRMRIETLNNQLGALQRQVAGAEAKIRDLEETLRRERDSHWR----QLADKDRELTEIRQAMTAQINEYEQLLEVKLALDMEISAYRKMLEGEEERLHLSPSPSSRVTVTRSSETVRTSGGGGGAVSRSASGAGSASGAGGAASSRSSVASSESEATSSVSVTQRASASGVIAVDEIDAGGRFVKLINDSQQEQDQAVGGWTVKRSI-HGHADIVYKFTGRTIVKAGDSITIWAGGAGVQHNPPRDLLMKQHSTWGSGDEVRVVVLNANGEEQ 350
BLAST of Intermediate filament 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010102.1 (pep scaffold:Pmarinus_7.0:GL478364:74479:82531:1 gene:ENSPMAG00000009106.1 transcript:ENSPMAT00000010102.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 66.6254 bits (161), Expect = 8.969e-12 Identity = 81/363 (22.31%), Postives = 166/363 (45.73%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEIL---KLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSA-LAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTD 1375
R ++K +++LN++ A +I++VRFLE QNK L+ +W E+ +I+ + EA N + + D L H+ K +LN L + +E+ +AK + EI E +++D++ + + +E LQG +DE+ FL+ I +L+EL A + + + + + ++ + D++ Y+ R+ ++ Y + Q +++ + EL ++E + + R+ + L+ + LE A+ + E + R+ + ++ +E+ +A + + + L++ KL+L +EI YRKLLEGEE+R ++
Sbjct: 137 RTQEKEAIKHLNDRFANFIDKVRFLEQQNKV-------LEAQWYALQEKTTTGSSIDE------MFEAYINGLRRQLD--GLGHD----KGQLN---------------------------GNLGQMQAVVEDFRAKYEAEINNRNAAEGEFVVVKKDVDGAYLSKVELETRLQGLVDEINFLRSIFTQELSELEAQIKHTNVLVEIDNSRNLDVDGIIADVRQQYETIAARSRAEADAFYQDKFQSLHSDSGRNDEELRMTRNEITELNRQMQRFRAEMEALKKQRAKLESAIAEAEGRGEADIREAKAAIAQLEEEIHKAKQEMARHVREYQELMNVKLALDIEIVTYRKLLEGEESRSSE 453
BLAST of Intermediate filament 1 vs. Ensembl Sea Lamprey
Match: desmb (desmin b [Source:ZFIN;Acc:ZDB-GENE-061027-102]) HSP 1 Score: 63.929 bits (154), Expect = 4.394e-11 Identity = 94/400 (23.50%), Postives = 176/400 (44.00%), Query Frame = 2
Query: 188 TNNQVPSQIIQRSFNYETRVIPSKSAAYGDV----GNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTE--AEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFW-KAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETR 1366
++ V S + RS+ + +P +S + +Y+ R +K +++ LN++ A YI++VR+LE QNK EL+ LK G++ V Y E++ L+ + EK RG E NL ELQ+ L++RL + + + + + Q ++D+++ T+ +++E +++ +E+ FLK+IH +L E+ T D K +L+ A++DI+++Y+ + E Y + D + L + K E + + + + I L+ SLER + ++ +Y+ ++ ++ + + LL K++L +EIA YRKLLEGEETR
Sbjct: 47 SSGSVASSLYGRSY---VKAMPGQSVDFSLAEALNADYRTTRTNEKVELQELNDRFANYIDKVRYLEQQNKALLAELALLK---GREPTRVGPLYEQELRELRAQVERLTGEKARGDVE--RANLLDELQR-----------------------------------LQQRLQEETAAREEAEKNL-------QAFRQDVDDATLARVDLERKVESLQEEIAFLKKIHDEELREVQVQVQEQTVHVEYDVGTKPDLTAALRDIRAEYEGIAAKNVAEAEEWYKSKFLDLSEAAVRNNEALRAAKQELMDYRRQVQAQQCDIDSLKGANESLERQIREMEERFSVESANYQDTITRLEDDIGNLKDEMARHLRDYQELLHVKMALDIEIATYRKLLEGEETR 396
BLAST of Intermediate filament 1 vs. Ensembl Nematostella
Match: EDO37225 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGD1]) HSP 1 Score: 107.071 bits (266), Expect = 3.137e-24 Identity = 142/566 (25.09%), Postives = 262/566 (46.29%), Query Frame = 2
Query: 239 TRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQ--------------KAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-SALAYRDTTK-----DNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW--TDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDID-HGRQLLKFVIPKKTFMDGNKTIKIW-AKG---FKPVGTNDL---EIPETNWGMGSDIHTILYNAVGEERAT 1846
T V S+ G+ K R ++K+++++LN++LA YI++V+ LE +N K E++ + ++ + +K Y E+ + ++LL E K + K + + ++ Q KA+ ELN D+ L K + E L S+L++ G+ EE L+D ++ + L +T+ +++E Q +E F KQ++ +L+++ S L +T + D KD ++ ++ +Q+++ DYD + + E Y + ++ + + + L +++EN+ + S++ LE K +L + DL+ ++K ++ E+ + E+ E + I + + L+ K++L +EI AYRKLLE EETR T +S V+ G +S V Q K+ + T +T T T +G + E DG+ I + N G+ E + I R + + KF K + + +W A+G KP +DL ++P +WG G++ T L NA GEE AT
Sbjct: 17 TPVSSSRIMGSSPPGSAKFTRAQEKAELQHLNDRLATYIDRVKNLEQENSKLRSEVTVSRKTVEREVDSMKSLYETELADARRLLDETAKEKAKQQIESSKNSNDAQEFKNKFDKEAAARKKAEKELN---DVRKLLHDKENQLTRRNQEALNLESVLRELQGECEE-----------LKDALKAAKYALEQETLTRVDLENRCQSLQEEQNFKKQMYDKELSDIRSQLKTVETKRVVVETDYKDKYEGLMAEKLQELREDYDSDARSFKEETELLYSSKFEELRIQRERDSEALAKLREENRNLSKSVDELSSQVHQLEAKNNALVSRVSDLQGLRAQDKEKHDNEILLRENEIAELRTSIDDALRDYEDLMGVKVALDMEITAYRKLLESEETRLEITPPASPVL----GGSSS--------VSQTRRGNKRARTEETEST------MTTTTTAEGAIQFTEADPDGKYIKIYNSGEKDEALGGWTIQRQVGTEDPSVYKFT--PKYVLKSQSHVTVWSAQGGGTHKP--PSDLVFKQLP--SWGSGNEARTALVNAGGEEMAT 544
BLAST of Intermediate filament 1 vs. Ensembl Medaka
Match: ENSORLT00000011270.2 (lamin-A [Source:NCBI gene;Acc:101160250]) HSP 1 Score: 121.324 bits (303), Expect = 2.481e-28 Identity = 125/529 (23.63%), Postives = 247/529 (46.69%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINL--EHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDN----KDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSAT---GEISAKS--TFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWA--KGFKPVGTNDLEI-PETNWGMGSDIHTILYNAVGEERA 1843
R ++K D+ NLN++LA YI++VR LEA+N ++ + + ++ +K Y E+ + +K L K R + + +L L +H+ KA++ S K + ++ +KR LE K ++ KL + + ++ L ++ ++ ++ E +Q +E+EF K +H +L E + N +DF +++L+ A+ +++S ++ +IQ+ + IE Y +++ + + + + +E ++I+ ST +++ L+ ++ + E + DL + L+ K +E+ + + + + + LLD KL+L +EI AYRKLLEGEE R S G+ +S ++ + + +++ E ++ A+ G A++ T + G V++ E DG+ + L N + + + R + G +L F P K + + + IWA G +DL + +WG G T L +A GEE A
Sbjct: 23 RLQEKEDLSNLNDRLAVYIDKVRSLEAENACLRVRITESETEVTRELTGLKNAYEAELADARKTLDSVAKERARLQLELGKLREDHKELKARNTKKESDLAAALQRLKDLEALMNSKDASLTTALGEKR--NLEVENRDLKAQVSKLDTGLGDARKQLQDEMLRRVDGENRIQTLKEELEFQKNLHSEELQETKRRHESRMVEMNNGQQQDF-ESKLAEALVEMRSQHELQIQLYKEEIEKTYNAKLESARQSADRSSHLVGAAHEELQQIRTRLESTSAQLSQLQKQLAAREAKIRDLEDALTRERDSTRRLLADKEREMADMRQRMQQQLDEYQELLDVKLALDMEICAYRKLLEGEEERLRLSPSPPPTRVTGSRSSVGRSVHSSAQSSPAKRRRPNEADSEASSYGGGALARTRITQQASASGRVTVDEVDLDGKYVRLSNKADEDQNLGSWQVRRQVGSGTPIL-FKFPAKFTLKAGQRVTIWASNAGGSHNPPSDLVWKSQPSWGTGDQFQTTLISASGEEMA 547
BLAST of Intermediate filament 1 vs. Ensembl Medaka
Match: lmnb2 (lamin B2 [Source:NCBI gene;Acc:101158263]) HSP 1 Score: 105.916 bits (263), Expect = 2.014e-23 Identity = 139/555 (25.05%), Postives = 264/555 (47.57%), Query Frame = 2
Query: 257 KSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKA-----KDELNLSRDMXXXXXXXXX--XXXXXXXXXXXXXSMLKKRLGKLEE--HKAKDKMEILKLRDEIQNLQR-DLNNQTIKYLNVECELQGKL--DEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSS-----------KTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIW-AKGFKPVGTND--LEIPETNWGMGSDIHTILYNAVGEERA 1843
+SAA + + R ++K D++ LN++LA YIE+VR LE +N + ++S ++ ++ +K Y E+ +L+++L E K R + + DL + +L++A K E +L+ + + + E LS + + L LG+++ KA+D + K + E + L R DL N+ + L+ + + + + +EM ++ + ++ E+ + A ++ ++ +L+ A+QD++ +D+++ + +E + K ENA + E+++ + R E +RSRI L ++ SL++ + SE+ R+ E LS+ K +E++E + + + LLD KL+L +EI AYRKLLEGEE R S + +T + T + + +V+ + E + T+ G+VSI DG + L N + + + R +D+G +++ PK G +++ +W A KP L + +WG GS I T L ++ GEE A
Sbjct: 14 RSAASTPLSPTRISRLQEKQDLQQLNDRLAVYIERVRALELENDRLMVKVSEKEEVTTREVTGLKALYEAELADLRRVLDETAKERARLQIDLGKAQADLEEATRSAKKKEADLAAAVSRANSLEGQLHKSEAALSTALSQSAALTSELGEVKSLLAKAEDGHAVAKRQLEAETLMRVDLENR-CQSLSEDLDFRRNMFDEEMRESRRHQEQRIVEVDSGARQE--------YEFKLTQALQDLRKQHDEQVSFYKEELEKTF-----QAKLENAHVSSEMSNAAMDAAR--EELQESRSRIESLSYQLSSLQKQV----GTSEDRIRELEEILSAERDRHRRAMERKEQEMSELREGMDAQLSEYQELLDVKLALDVEINAYRKLLEGEEHRLKLSPSP-----SARVTVSRVTGSSSSRSTKRKWSEVEAQEEAGQAEEQLLVSEEATSTGSVSICPTDMDGTSVKLTNETDQDQPLGSWRLRRQVDNGEEVVYKFSPKFVLKAG-QSVTVWSADAGKPHNPPSELLWKSQASWGTGSTIVTSLIDSSGEEVA 542
BLAST of Intermediate filament 1 vs. Ensembl Medaka
Match: lmna (lamin A/C [Source:NCBI gene;Acc:101162240]) HSP 1 Score: 97.4413 bits (241), Expect = 1.179e-20 Identity = 134/560 (23.93%), Postives = 251/560 (44.82%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDL--INLEHELQKA---KDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLE--EHKAKD-KMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNEL-----SALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERAL----VDLRHESEENKRDYEI---ELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRW----TDKSSTVVV-------HENGTLTSNLKTFVNQVKQETIVQKKVQ---ETNTSATGEISAKSTFNR--TTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETN--------WGMGSDIHTILYNAVGEERAT 1846
R ++K D+ NLN++LA YI++VR LEA+N +S + +D +K Y E+ + + L + K + + + DL I EH+ KA K EL+L + + + + + L LG+ E + KD K ++ KL + + ++ L ++ +K ++ E LQ +E+EF K I+ + E S + D ++ + ++ +L+ A+ ++++ +++++ + + +E Y R+++ + +A+ L E E TRSR+ L ++ L++ L +R E R+ ++ L K +E+ E + + + + LLD KL+L +EI+ YR LLEGEE R + S+ V+V H + L S+ ++ KK + S G KS ++ + G + + E +G+ I L N + + + + G + + P K + T+ IWA GT++ P T+ WG G + IL ++ GEE A
Sbjct: 20 RLQEKEDLCNLNDRLAVYIDKVRSLEAENAGLRLRISESESLVTRDLSGIKAAYENELADARHALDQVAKEKARLQLDLGKIREEHKELKARNTKKELDLEAALARLRDLEALLNSKD--------AALATALGEKRNLEAEVKDLKAQLAKLDMNLADARKQLQDEMLKRVDAENRLQTVKEELEFQKNIYNEETRESKRRSESRMVEIDCSRQQE--FENKLAAALVELRAQHEEQVSIYKEELEKTYNSRLENAR-HSAERTTHLVGAAHE------ELQQTRSRLEGLTLQMTQLQKQLSASEAKVRELEEALSRERDLMRRRLEDKDREMAENRARMQQQLEDYQELLDIKLALDMEISHYRTLLEGEEERLRLSPSPPSAKVIVTRSTGSSHASRLLHSSAVASSSRTSSGASSTKKRRLNDSVAASMVGGTVVKSHISQQASASGRIVVNEVDLEGKFIRLSNKSDEDQSLGSWQVKAQVGDGNP-VTYKFPSKFSLKAGATVTIWAASGG--GTHN---PPTDLVWKNQNSWGTGDSLEIILVSSSGEEMAA 556
BLAST of Intermediate filament 1 vs. Ensembl Medaka
Match: lmnl3 (lamin-L(III) [Source:NCBI gene;Acc:101168604]) HSP 1 Score: 92.0485 bits (227), Expect = 4.753e-19 Identity = 115/537 (21.42%), Postives = 252/537 (46.93%), Query Frame = 2
Query: 299 REKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTE--AEKNR-----GKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKK--RLGKLEEHKAKDKMEILKLRDEIQNLQR-------DLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTK------DNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETN--WGMGSDIHTILYNAVGEE 1837
R +++ ++R+LN++LA YI++V+ LE + L ++ ++T V+ Y E+ ++++ L E AE+ R G D++ L+ QK ++ D+ + ++ ++ S+E +L + RLG E+ L+ +++N +R L+++ ++ + +E ++Q +++E K I + ++ E+ + R T+ + ++++L+ MQ ++ D+ ++Q + ++E + ++Q+ + + + +++ ++E + + + S RS++ + + LE +L+ ++ + ++ LS K +EL + ++ + LLD KL+L +EI AYRK+LE EE R S T H T V +V++ ++ K ++ + + K T KG V++ E G+ + ++N ++ + ++ R H + F P + G +T+ IW+ G + E N WG D+ +L N EE
Sbjct: 27 RVQERGELRHLNDRLANYIQRVQELEQEKGAMLLRLQEQEEATARETRGVRRLYEEELADVRRALDELAAERARLQIEQGNQREDILKLQSRNQKKEN------DLAAAVTQRRKVEAVLSSKEAENRKLLSENGRLGG----------EVADLQVQLENAERLLAETKNQLSSEILRRVEMENQVQTLKEQLELQKNISRQEILEVRS---RQETRLVEVESGRRREFESKLAETMQQLREDHTLQLQQYKEAMEKTFSTKLQNAQQAAEENGVSVSTAREELEASREKLESLRSQLQQNQKDKLVLEERFQELQRTLDQERDAWQQRLSLKERELLSMRTQMNSQLENHQNLLDVKLALDMEINAYRKMLEVEEQRL-QLSPTPPRH----------TSVARVQEHHQLRGKKRKHEEATRSSPAYKICRRSTRKGGVTVAEVDVGGKYVQIQNNSDQEQPLGGWVVRRVYPHSGD-VSFQFPPSCVLAGGQTLTIWSSGAADEAEPGDMVLENNGSWGAVGDMRVVLLNPSHEE 532
BLAST of Intermediate filament 1 vs. Ensembl Medaka
Match: lmnl3 (lamin-L(III) [Source:NCBI gene;Acc:101168604]) HSP 1 Score: 90.5077 bits (223), Expect = 1.772e-18 Identity = 115/540 (21.30%), Postives = 253/540 (46.85%), Query Frame = 2
Query: 290 KKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTE--AEKNR-----GKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKK--RLGKLEEHKAKDKMEILKLRDEIQNLQR-------DLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTK------DNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETN--WGMGSDIHTILYNAVGEE 1837
+ R +++ ++R+LN++LA YI++V+ LE + L ++ ++T V+ Y E+ ++++ L E AE+ R G D++ L+ QK ++ D+ + ++ ++ S+E +L + RLG E+ L+ +++N +R L+++ ++ + +E ++Q +++E K I + ++ E+ + R T+ + ++++L+ MQ ++ D+ ++Q + ++E + ++Q+ + + + +++ ++E + + + S RS++ + + LE +L+ ++ + ++ LS K +EL + ++ + LLD KL+L +EI AYRK+LE EE R S T H T V +V++ ++ K ++ + + K T KG V++ E G+ + ++N ++ + ++ R H + F P + G +T+ IW+ G + E N WG D+ +L N EE
Sbjct: 24 QPPRVQERGELRHLNDRLANYIQRVQELEQEKGAMLLRLQEQEEATARETRGVRRLYEEELADVRRALDELAAERARLQIEQGNQREDILKLQSRNQKKEN------DLAAAVTQRRKVEAVLSSKEAENRKLLSENGRLGG----------EVADLQVQLENAERLLAETKNQLSSEILRRVEMENQVQTLKEQLELQKNISRQEILEVRS---RQETRLVEVESGRRREFESKLAETMQQLREDHTLQLQQYKEAMEKTFSTKLQNAQQAAEENGVSVSTAREELEASREKLESLRSQLQQNQKDKLVLEERFQELQRTLDQERDAWQQRLSLKERELLSMRTQMNSQLENHQNLLDVKLALDMEINAYRKMLEVEEQR-LQLSPTPPRH----------TSVARVQEHHQLRGKKRKHEEATRSSPAYKICRRSTRKGGVTVAEVDVGGKYVQIQNNSDQEQPLGGWVVRRVYPHSGD-VSFQFPPSCVLAGGQTLTIWSSGAADEAEPGDMVLENNGSWGAVGDMRVVLLNPSHEE 532
BLAST of Intermediate filament 1 vs. Planmine SMEST
Match: SMESG000046938.1 (SMESG000046938.1) HSP 1 Score: 1175.23 bits (3039), Expect = 0.000e+0 Identity = 605/606 (99.83%), Postives = 606/606 (100.00%), Query Frame = 2
Query: 32 MQKTVTQNSTIIREKSNSTVSLKTMTENNQIENSKEKTVSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
MQKTVTQNSTIIREKSNSTVSLKTMTENNQIENSKEKTVSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMENELLKKIEICEEKLSEEEALISMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAE+SLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY
Sbjct: 1 MQKTVTQNSTIIREKSNSTVSLKTMTENNQIENSKEKTVSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMENELLKKIEICEEKLSEEEALISMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAEISLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 606
BLAST of Intermediate filament 1 vs. Planmine SMEST
Match: SMESG000062826.1 (SMESG000062826.1) HSP 1 Score: 360.918 bits (925), Expect = 4.831e-116 Identity = 225/587 (38.33%), Postives = 369/587 (62.86%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPS---------QIIQRSFNYETRVIPSKSA--AYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQK-KVQETNTSAT----GEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDG---NKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
+ PIS R ++I RT V + + I+ S +Y P ++ + V N REK+K+++++LN++ A YI++VR LE +NK+ S EL +LKD+WGK+T +K Y+ +M L++ L +AE + + E + LE + +A+ ELN + + + I+ LS+ E I+ L+KRLG LEE K +D EI++L++E+ L++DL +T++++ ELQ +D++EFLK+I ++++ EL++L Y+D+T +NKDFW+ E++ A++DIQ++YD ++ L +E+QY +++Q+ +T ++ +E +++EN R+K++ R+R+P+LE + LER L LR E EE R++++E ++ KEL + + I+L+ LLD KLSL+LEI AYRK+LEGEE R KS ++N T ++ V + +I Q+ T T T GE+SAK++F RT KGNV+I EC+ DG+ IILEN G +E+IS ++ R+ D+GR ++K VIP KT ++ N+ KIWA+G +P G+ D E E+NWG G+ I T+L N+ GEE+AT+
Sbjct: 22 IQPISGYRNVVITRTGPTVSTVGTQGGSNIRTIEMSKSYGLSSTPGATSNIVHNGVNNLMNGREKEKNELQDLNDRFANYIDKVRNLEDENKRLSDELVDLKDQWGKETARIKTFYDNDMIQLRRSLDQAEGAKAQMEMKINTLEDLILEAQTELNDATQLHLADKETIDKMASTLSDYEHEIANLRKRLGGLEEEKVRDNKEIMRLKEELNLLKQDLEKETLEHITAHNELQSLVDQIEFLKKIFESEVRELASLVYKDST-ENKDFWRNEMAQALRDIQTEYDRKLDTLHYDMEAQYTLKIQEIRTTQSQENVETVQLREENTRLKDQLAEMRNRLPELEARNNELERLLELLRREIEEKNREFDLEKNNLRKELLNRKAELEGILIELQILLDAKLSLELEIIAYRKMLEGEEYRVNRKS-----NQNLNQTGRSVDTMDHVTRTSISQQHAAPSTKTQVTSVIKGEMSAKTSFQRTAKGNVTIQECSPDGKFIILENTGSQEEDISGYILQRNTDNGRIVIKHVIPSKTILEPTGKNRYYKIWARGNRPQGSGDPECSESNWGFGAQIVTVLQNSKGEEKATH 602
BLAST of Intermediate filament 1 vs. Planmine SMEST
Match: SMESG000046289.1 (SMESG000046289.1) HSP 1 Score: 350.132 bits (897), Expect = 2.385e-112 Identity = 213/582 (36.60%), Postives = 346/582 (59.45%), Query Frame = 2
Query: 146 VSPISSQRTIIINRTNNQVPSQIIQRSFNYETRVIPSKSAAYGDVGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLE---HELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELT----EADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETR--WTDKSSTVVVHENGTLTSNL--KTFVNQVKQETIVQKKVQETNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDG---NKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
S S++ T+ IN+++ V +++S+N+ + + +V + + RE++K +M++LNE+LA YIE+VRFLEAQNK+ + EL+ L+++WGK+ E ++ Y IEM LKKLL EAE R + + LE HE + DE N M+ E+++K+ + E +L++R+ LEE + + K I +LRDEI+ + DL+ +T+ ++ E E+Q + DE++F+K H ++ EL+ALAYRD+T +N+DFW++E+ +++++Q +YD +++ +R +E+ + V++Q+ + + + +E +K+EN R+KN+ + RS+ P++E K LER L +LR + + D+E E +L E DSI+ E + ++D KLSL+LEIAAYRKLLEGEE+R + + +G + N+ KT V+ + + E +AK RT KGNV I E + DG+ IILEN GK E+IS I R+ID+ R ++++ IP T + K +KIW+KG +P G+NDLE NWG G+ I T L N EERAT+
Sbjct: 2 ASRTSARSTVTINKSSPAVKEYEMRQSYNFSGAPMGGSVQIHSNVSSAVEGREREKREMQDLNERLANYIEKVRFLEAQNKRLTNELNTLRERWGKEAERIRALYEIEMDQLKKLLDEAEAARSELLPKINKLEEQLHEYLQGIDEANNQHGMDQEMIEKLNRQLSECEGEI---GLLRRRIAALEEERGRSKKTISRLRDEIKRTRMDLDQETMNHIASESEVQSRKDEIDFMKDSHDNEMKELAALAYRDSTAENRDFWRSEMGSSLRELQIEYDRKLEAMRGDLENHHNVKVQELRHSSPREGVESIHLKEENIRLKNQLSNLRSKCPEMEAKNAQLERFLEELRRDLDRQINDFESERDKLRSDLQRTQDELDSIMKE----FQNVMDMKLSLELEIAAYRKLLEGEESRSGLRNMMEQTIFKTSGGIEGNIISKTAVSNLMK----------------NERNAKVNHQRTAKGNVIIHETSADGKFIILENTGKKDEDISGFKIIRNIDNDRSIIRYEIPNSTILKPEGQQKFLKIWSKGNRPTGSNDLECSSANWGTGTHIFTALLNKSNEERATH 560
BLAST of Intermediate filament 1 vs. Planmine SMEST
Match: SMESG000030598.1 (SMESG000030598.1) HSP 1 Score: 261.922 bits (668), Expect = 1.099e-77 Identity = 179/537 (33.33%), Postives = 295/537 (54.93%), Query Frame = 2
Query: 278 VGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQE-------------TNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
V + KK R ++K D+++LNE+ A YIE+ RFLEAQNK+ + E+ LK +D ++K Y +E+ L+ L+ E+EK++ E + +LE+E+ + L + D+ ++ I+ + +S E + L++ G K+K E+ LRD+++ L++D + + +L +E ELQ + +EF KQIH T++ EL+ +AYRD TK+N +W++E+ A++DIQ++Y++++ ++ +E+ YG++MQ+ +T + +E K+EN RIK++ S RSRI DLE + E L ++R EE +R E++L ++LT + +L++LLD KL L+LEIAAY KLLE EE+R N TL S +F + T T S + F RTTKGN+SI E G IILENIG E + M I R +D + F I K ++ + I + AKG ++EI + +WG+G+++ T L ++ G E+A +
Sbjct: 145 VTSMKKGRAQEKRDLQDLNERFASYIEKARFLEAQNKQLANEIEKLKGGTVQDNSKIKEIYEVEINQLRALVNESEKSKAPLEAQVDSLEYEIDDLRKRLMMLEDINSQYKSTIDKQRKDISGFEGELVELRRFKGTQGADVNKEKEEVKTLRDDLKKLRQDYEKEALAHLTLEHELQSLKEALEFEKQIHDTEVKELATVAYRDPTKENMVYWQSEMGRALRDIQTEYENKLTGIKQELEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRSRIADLEMQNAEYEHNLNNIRANYEETQRSLELQLLYLQEQLTGTQQELTVALTELQSLLDAKLGLELEIAAYAKLLEFEESRV-----NFSADGNATL-SQFMSFTSSSGAGGAGGSGFGSGSRIGGSSGFSGMTERETTDYQSKRMKFRRTTKGNISIAETDLIGSTIILENIGTKVESLEGMTIKRVVDGSENKISFTISGKVNLNAGEKISLCAKGKITGKGREIEIDDASWGVGNNVVTTLCDSEGAEKAAH 675
BLAST of Intermediate filament 1 vs. Planmine SMEST
Match: SMESG000030598.1 (SMESG000030598.1) HSP 1 Score: 259.996 bits (663), Expect = 6.034e-77 Identity = 177/537 (32.96%), Postives = 294/537 (54.75%), Query Frame = 2
Query: 278 VGNYKKEREKDKSDMRNLNEKLAGYIEQVRFLEAQNKKQSGELSNLKDKWGKDTEEVKIRYNIEMQNLKKLLTEAEKNRGKTEFDLINLEHELQKAKDELNLSRDMXXXXXXXXXXXXXXXXXXXXXXSMLKKRLGKLEEHKAKDKMEILKLRDEIQNLQRDLNNQTIKYLNVECELQGKLDEMEFLKQIHQTQLNELSALAYRDTTKDNKDFWKAELSLAMQDIQSDYDDRIQMLRSSIESQYGVRMQDTKTENAKLLMELNSIKDENKRIKNEWGSTRSRIPDLENKIISLERALVDLRHESEENKRDYEIELSSKTKELTEADSIIHETEIQLKTLLDDKLSLQLEIAAYRKLLEGEETRWTDKSSTVVVHENGTLTSNLKTFVNQVKQETIVQKKVQE-------------TNTSATGEISAKSTFNRTTKGNVSILECTTDGRCIILENIGKNKEEISDMLINRDIDHGRQLLKFVIPKKTFMDGNKTIKIWAKGFKPVGTNDLEIPETNWGMGSDIHTILYNAVGEERATY 1849
V + KK R ++K D+++LNE+ A YIE+ RFLEAQNK+ + E+ LK +D ++K Y +E+ L+ L+ E+EK++ E + +LE+E+ + L + D+ ++ I+ + +S E + L++ G K+K E+ LRD+++ L++D + + +L +E ELQ + +EF KQIH T++ EL+ +AYRD TK+N +W++E+ A++DIQ++Y++++ ++ +E+ YG++MQ+ +T + +E K+EN RIK++ S RSRI DLE + E L ++R EE +R E++L ++LT + +L++LLD KL L+LEIAAY KLLE EE+R N TL+ + + T T S + F RTTKGN+SI E G IILENIG E + M I R +D + F I K ++ + I + AKG ++EI + +WG+G+++ T L ++ G E+A +
Sbjct: 145 VTSMKKGRAQEKRDLQDLNERFASYIEKARFLEAQNKQLANEIEKLKGGTVQDNSKIKEIYEVEINQLRALVNESEKSKAPLEAQVDSLEYEIDDLRKRLMMLEDINSQYKSTIDKQRKDISGFEGELVELRRFKGTQGADVNKEKEEVKTLRDDLKKLRQDYEKEALAHLTLEHELQSLKEALEFEKQIHDTEVKELATVAYRDPTKENMVYWQSEMGRALRDIQTEYENKLTGIKQELEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRSRIADLEMQNAEYEHNLNNIRANYEETQRSLELQLLYLQEQLTGTQQELTVALTELQSLLDAKLGLELEIAAYAKLLEFEESRV-----NFSADGNATLSQFMSFTSSSGAGGGGGSSGFGSGSRIGGSSGFSGMTERETTDYQSKRMKFRRTTKGNISIAETDLIGSTIILENIGTKVESLEGMTIKRVVDGSENKISFTISGKVNLNAGEKISLCAKGKITGKGREIEIDDASWGVGNNVVTTLCDSEGAEKAAH 676 The following BLAST results are available for this feature:
BLAST of Intermediate filament 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Intermediate filament 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Intermediate filament 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Intermediate filament 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Intermediate filament 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031632 ID=SMED30031632|Name=Intermediate filament 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2008bpback to top protein sequence of SMED30031632-orf-1 >SMED30031632-orf-1 ID=SMED30031632-orf-1|Name=SMED30031632-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=616bp MQKTVTQNSTIIREKSNSTVSLKTMTENNQIENSKEKTVSPISSQRTIIIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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