Sphingosine-1-phosphate phosphatase 1-like

Overview
NameSphingosine-1-phosphate phosphatase 1-like
Smed IDSMED30031613
Length (bp)1871
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Sphingosine-1-phosphate phosphatase 1-like (SMED30031613) t-SNE clustered cells

Violin plots show distribution of expression levels for Sphingosine-1-phosphate phosphatase 1-like (SMED30031613) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Sphingosine-1-phosphate phosphatase 1-like (SMED30031613) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Sphingosine-1-phosphate phosphatase 1-like (SMED30031613) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031613

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymaSMED30031613h1SMcG0005219 dd_Smed_v4_4050_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30031613h1SMcG0005219 Contig39968uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30031613h1SMcG0005219 Contig39968newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Human
Match: SGPP1 (sphingosine-1-phosphate phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:17720])

HSP 1 Score: 125.946 bits (315), Expect = 1.930e-30
Identity = 90/274 (32.85%), Postives = 148/274 (54.01%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIR-------NYEEIVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            +GR++++ W +VMY+GQ  KD+ +  RP+SPPVV LE  Y  EY MPSTHAM+  A+P  +VL  + +  Y +   ++    WC L+  SR+Y G+HS+ D+I G +  I+++A   P+++   +   T      I+  + L + +       W + R DT  ILGS  G+  GSH+ Y +        +   +  P  T+T+    I R L+G+V ++  R + K I + +  KI N+    I + RQ+   EL Y+   Y ++G  I+F +P
Sbjct:  159 VGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHLALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVTLFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITYGMVGFSITFFVP 432
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Human
Match: SGPP1 (sphingosine-1-phosphate phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:17720])

HSP 1 Score: 125.946 bits (315), Expect = 1.930e-30
Identity = 90/274 (32.85%), Postives = 148/274 (54.01%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIR-------NYEEIVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            +GR++++ W +VMY+GQ  KD+ +  RP+SPPVV LE  Y  EY MPSTHAM+  A+P  +VL  + +  Y +   ++    WC L+  SR+Y G+HS+ D+I G +  I+++A   P+++   +   T      I+  + L + +       W + R DT  ILGS  G+  GSH+ Y +        +   +  P  T+T+    I R L+G+V ++  R + K I + +  KI N+    I + RQ+   EL Y+   Y ++G  I+F +P
Sbjct:  159 VGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHLALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVTLFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITYGMVGFSITFFVP 432
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Human
Match: SGPP2 (sphingosine-1-phosphate phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:19953])

HSP 1 Score: 111.309 bits (277), Expect = 1.142e-25
Identity = 82/276 (29.71%), Postives = 146/276 (52.90%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLG---SHIDYIIRNYEEIV-----LPEAT---LTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            + R++++ W +VMYIGQ  KD+ +  RPSSPPVV LE+R + EYGMPSTHAMAA A+   L+++   +  Y   L ++ +V++  L+  SRLY G+H++ DV+ G+++  +L+    P       +        + + ++   +   YP    +   R+DT  IL +  GV +G   +H   ++    E +     +P  T   L + + +F +G+V+I+  R L + + ++V      +  +  E R+    E+ YK   YT +G+  +  +P L
Sbjct:  117 LSRRLIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPML 392
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Zebrafish
Match: SGPP2 (sphingosine-1-phosphate phosphatase 2 [Source:NCBI gene;Acc:100330698])

HSP 1 Score: 125.946 bits (315), Expect = 9.740e-31
Identity = 91/278 (32.73%), Postives = 150/278 (53.96%), Query Frame = 2 
Query:  953 RQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHID------YIIRNYEEIVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRLSYKCDL 1759
            R+++  W +VMYIGQ MKD+ ++ RP SPPVV LE R   EYGMPSTHAMAA A+   L+L+  +++ +   L +  +VL  +L+  SRLY G+HS  DVI G+ ++  ++A   P+     ++ +      ++  ++ L +A  YP+   + + R DT +IL    G  +G  ++      + +     + LP  TL       ARF++GV+++V  R   + + +RV   I        E R+ K  E+ YK + Y  +G++ S ++ RL  K  L
Sbjct:  131 RRLVNMWVVVMYIGQVMKDVLKLPRPPSPPVVKLETRVDAEYGMPSTHAMAATAISFTLLLSAEERVQFPFELGLAVAVLMSVLVCLSRLYTGMHSALDVICGVAISAFIIAVSYPYWGTIDYLQLHNPVAPVVGMVLPLFLAYTYPELDHYSTTRGDTTIILACSAGCSVGYWVNERLGLTFYLTGPFPVTLPPLTLAALGCGFARFVIGVLMLVLTRQTVRFVSLRVLCWIFGASASDPEARKRKEIEVPYKFTTYVAIGLVNSILVNRLFVKMGL 408
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Zebrafish
Match: SGPP2 (sphingosine-1-phosphate phosphatase 2 [Source:NCBI gene;Acc:100330698])

HSP 1 Score: 120.939 bits (302), Expect = 2.014e-29
Identity = 89/271 (32.84%), Postives = 145/271 (53.51%), Query Frame = 2 
Query:  974 SIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHID------YIIRNYEEIVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRLSYKCDL 1759
             +VMYIGQ MKD+ ++ RP SPPVV LE R   EYGMPSTHAMAA A+   L+L+  +++ +   L +  +VL  +L+  SRLY G+HS  DVI G+ ++  ++A   P+     ++ +      ++  ++ L +A  YP+   + + R DT +IL    G  +G  ++      + +     + LP  TL       ARF++GV+++V  R   + + +RV   I        E R+ K  E+ YK + Y  +G++ S ++ RL  K  L
Sbjct:   84 EVVMYIGQVMKDVLKLPRPPSPPVVKLETRVDAEYGMPSTHAMAATAISFTLLLSAEERVQFPFELGLAVAVLMSVLVCLSRLYTGMHSALDVICGVAISAFIIAVSYPYWGTIDYLQLHNPVAPVVGMVLPLFLAYTYPELDHYSTTRGDTTIILACSAGCSVGYWVNERLGLTFYLTGPFPVTLPPLTLAALGCGFARFVIGVLMLVLTRQTVRFVSLRVLCWIFGASASDPEARKRKEIEVPYKFTTYVAIGLVNSILVNRLFVKMGL 354
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Zebrafish
Match: sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:ZFIN;Acc:ZDB-GENE-090319-2])

HSP 1 Score: 115.546 bits (288), Expect = 3.764e-27
Identity = 89/316 (28.16%), Postives = 165/316 (52.22%), Query Frame = 2 
Query:  827 QSTLLSCKHM*FNINLRRKLFS*LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEE-------IVLPEATLT---MHIARFLLGVVVIVCCRFLYKPILVRVTAKILNL-DPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            Q  L+  K + +   L  +L + L Y  +  +  +   + + R++++ W  VMY+GQ  KD+F+  RP+SPPVV +E  Y  EY MPSTHAM+  A+P  L L  + +  Y + L +  ++ WC+L+  SR+Y G+HS+ D+I G + +++++    P ++       T     +++  + + + L       W + R DT  ILGS  G+ L SH++Y +    +       +  P  TL+   + + RF LGV++++  R + K + + +   +  +    + + RQ+   EL Y+  +Y  +G+   F++P L
Sbjct:  100 QEFLIENKFLFYLFTLGTELGNELFYISFFPFFMWNVDAYVSRRLVVVWVWVMYLGQCTKDVFRWPRPASPPVVKVEMFYNSEYSMPSTHAMSGTAIPLSLFLLTYGRWEYPMLLGLSLAISWCVLVCLSRIYMGMHSILDIIAGFLYSLLILVVFSPALDIIDTFNRTHPYAPLMIISLHVGLGLFSFTLDTWSTSRGDTAQILGSGAGIALASHVNYHLGLLPDPPASAFPLQPPSFTLSLVALCLLRFFLGVLILLATRAVMKALTIPLVCWVFGIPSNDVRKARQHMEVELPYRYIVYGTVGLNALFLVPFL 415
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Zebrafish
Match: sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:ZFIN;Acc:ZDB-GENE-090319-2])

HSP 1 Score: 114.39 bits (285), Expect = 7.536e-27
Identity = 89/316 (28.16%), Postives = 165/316 (52.22%), Query Frame = 2 
Query:  827 QSTLLSCKHM*FNINLRRKLFS*LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEE-------IVLPEATLT---MHIARFLLGVVVIVCCRFLYKPILVRVTAKILNL-DPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            Q  L+  K + +   L  +L + L Y  +  +  +   + + R++++ W  VMY+GQ  KD+F+  RP+SPPVV +E  Y  EY MPSTHAM+  A+P  L L  + +  Y + L +  ++ WC+L+  SR+Y G+HS+ D+I G + +++++    P ++       T     +++  + + + L       W + R DT  ILGS  G+ L SH++Y +    +       +  P  TL+   + + RF LGV++++  R + K + + +   +  +    + + RQ+   EL Y+  +Y  +G+   F++P L
Sbjct:  101 QEFLIENKFLFYLFTLGTELGNELFYISFFPFFMWNVDAYVSRRLVVVWVWVMYLGQCTKDVFRWPRPASPPVVKVEMFYNSEYSMPSTHAMSGTAIPLSLFLLTYGRWEYPMLLGLSLAISWCVLVCLSRIYMGMHSILDIIAGFLYSLLILVVFSPALDIIDTFNRTHPYAPLMIISLHVGLGLFSFTLDTWSTSRGDTAQILGSGAGIALASHVNYHLGLLPDPPASAFPLQPPSFTLSLVALCLLRFFLGVLILLATRAVMKALTIPLVCWVFGIPSNDVRKARQHMEVELPYRYIVYGTVGLNALFLVPFL 416
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Zebrafish
Match: si:ch211-212g7.6 (si:ch211-212g7.6 [Source:ZFIN;Acc:ZDB-GENE-030131-4695])

HSP 1 Score: 98.5969 bits (244), Expect = 1.818e-21
Identity = 77/276 (27.90%), Postives = 145/276 (52.54%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDY---IIRNYEEIVLP-------EATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNL-DPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            + RQ+++ W+ V+++GQ+ KD+ +  RP+SPPVV +E  Y  EY MPSTHAM+  A+P  L L    +  Y     +  ++ W +L+  SR+Y G+HS+ +VI G + +++++A + P ++D     ++     +++ ++ +  +L+      W + R DT   L +  G  L   +++   ++ +  E  LP       EA LT  + R L+GV V++  R   K + + +  KI  +    + + RQ+   EL Y+  +Y  +      ++P L
Sbjct:  154 VSRQLIVVWAWVLFLGQSTKDVVRWTRPASPPVVKVEVFYNSEYSMPSTHAMSGTALPFSLFLLTCSRWEYPFMFGLSIALFWSILVCISRIYMGMHSVLEVITGFLYSVLILAVLHPMLDDIDTFYLSHSYAPLVVLLVHVGFSLVAFSLDTWSTSRGDTAQALATAAGAALACRLNHQLGLLPDPPEEALPLALPLIDEALLTRSVMRMLMGVAVLLAVRAAMKVVAIPLACKIFGVPSDDVRKARQHAQVELAYRFLVYGTVAYCCVCLVPLL 429
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Xenopus
Match: sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:NCBI gene;Acc:549040])

HSP 1 Score: 122.479 bits (306), Expect = 1.781e-29
Identity = 96/276 (34.78%), Postives = 150/276 (54.35%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIR-----NYEEI--VLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            +GR+V++ W  VMY+GQ  KDL +  RP SPPVV LE  Y  EYGMPSTHAM+  A+P  ++L  + +  Y     ++ +++WC L+  SR+Y G+HS+ DVI G + AI+++    P +E   +  +T     +I+  + L M +       W + R DT  ILGS  GV  GSH +Y++        +E+  + P  T+T+    + +FL+GVVV++  R   K I + +  K+  +    I + RQ    EL Y+   Y  +G     I+P L
Sbjct:  126 VGRKVIVIWVWVMYLGQCTKDLIRWPRPPSPPVVKLEVFYNTEYGMPSTHAMSGTAIPISILLLTYGRWQYPFTFGLILALIWCSLVCLSRVYMGMHSILDVIAGFLYAILILIVFHPALEIIDNFNLTYKYAPLIIISLHLAMGIFSFTLDTWSTSRGDTAQILGSGAGVACGSHFNYMLGLMVDPTPKELPFIPPSITVTLIGKAMLKFLIGVVVLLLLRAAMKKISIPLACKVFGIPCDDIRKARQRMEVELPYRYITYGFVGFGAMVIVPYL 401
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Xenopus
Match: ndst4 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 [Source:Xenbase;Acc:XB-GENE-951845])

HSP 1 Score: 117.472 bits (293), Expect = 6.198e-28
Identity = 90/273 (32.97%), Postives = 148/273 (54.21%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRN---YEEIVLPEATLTMH-----IARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            IG ++++ W+IVMY+GQA KDL +  RPSSPPVV LE R   EYGMPSTHA+AA A+    +L    +  Y  +L  L+++    L+S SRLY G+H++ DVI G ++A++ +A   P  +    +++      I    +    +  YP    + + R+DT  I+G   G  +G  +  +  N        LP   +++H       RFLLGV++++  RF+ K + ++   K  N+  +    RQ    E+ YK   YT +G++ + ++P+L
Sbjct:  110 IGHRLVVVWAIVMYLGQASKDLLKWPRPSSPPVVKLETRVDAEYGMPSTHAIAATAISFTFLLATVGRYQYPFWLGFLAALFLSTLVSLSRLYTGMHTVLDVICGALIALLFLALTYPVWDKMDEVLLAHPLSPIFTVTVGFLSSYNYPKMDHYSTTRADTTTIIGVAVGTCVGVSVSKLQLNSIPSSHFPLPIPPISLHSVVLQTERFLLGVLLLLITRFVAKTLSLQTLGKWHNVCTQDHLVRQRLEIEVPYKFVTYTSIGLVATGVVPQL 382
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Xenopus
Match: ndst4 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 [Source:Xenbase;Acc:XB-GENE-951845])

HSP 1 Score: 117.472 bits (293), Expect = 7.338e-28
Identity = 90/273 (32.97%), Postives = 148/273 (54.21%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRN---YEEIVLPEATLTMH-----IARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            IG ++++ W+IVMY+GQA KDL +  RPSSPPVV LE R   EYGMPSTHA+AA A+    +L    +  Y  +L  L+++    L+S SRLY G+H++ DVI G ++A++ +A   P  +    +++      I    +    +  YP    + + R+DT  I+G   G  +G  +  +  N        LP   +++H       RFLLGV++++  RF+ K + ++   K  N+  +    RQ    E+ YK   YT +G++ + ++P+L
Sbjct:  122 IGHRLVVVWAIVMYLGQASKDLLKWPRPSSPPVVKLETRVDAEYGMPSTHAIAATAISFTFLLATVGRYQYPFWLGFLAALFLSTLVSLSRLYTGMHTVLDVICGALIALLFLALTYPVWDKMDEVLLAHPLSPIFTVTVGFLSSYNYPKMDHYSTTRADTTTIIGVAVGTCVGVSVSKLQLNSIPSSHFPLPIPPISLHSVVLQTERFLLGVLLLLITRFVAKTLSLQTLGKWHNVCTQDHLVRQRLEIEVPYKFVTYTSIGLVATGVVPQL 394
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Mouse
Match: Sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:MGI Symbol;Acc:MGI:2135760])

HSP 1 Score: 115.546 bits (288), Expect = 3.797e-27
Identity = 85/274 (31.02%), Postives = 147/274 (53.65%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEE-------IVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            +GR++++ W +VMY+GQ  KD+ +  RP+SPPV+ LE  Y  EY MPSTHAM+  A+P  + L  + +  Y +   ++    W  L+  SR+Y G+HS+ DVI G +  I+++    P ++   +   T     +I+  + L + +       W + R DT  ILGS  G+  GSH  Y +    E       + +P  T+T+    I R +LG+++++  R + K I + +  K+ ++    I + RQ+   EL Y+   Y ++G  I+F++P
Sbjct:  148 VGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPVIKLEVFYNSEYSMPSTHAMSGTAIPIAMFLLTYGRWQYPLIYGLILIPCWSSLVCLSRIYMGMHSILDVIAGFLYTILILIIFYPLVDLIDNFNQTYKYAPLIIIGLHLILGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHAAYTLGLSLEPSLHMLPLAIPPLTVTLFGKAILRIVLGMLLVLFVRDIMKKITIPLACKLSSIPCHDIRQARQHMEVELPYRYITYGMVGFSITFLVP 421
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Mouse
Match: Sgpp2 (sphingosine-1-phosphate phosphotase 2 [Source:MGI Symbol;Acc:MGI:3589109])

HSP 1 Score: 110.923 bits (276), Expect = 5.670e-26
Identity = 85/307 (27.69%), Postives = 158/307 (51.47%), Query Frame = 2 
Query:  860 FNINLRRKLFS*LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDY-------------IIRNYEEIVLPEATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            F+  L +++F    Y  +  + ++     + R++++ W +VMYIGQ  KD+ +  RPS PPVV LE+R + EYGMPSTHAMAA A+   L+++   +  Y   L ++ +V++  L+  SRLY G+H++ D++ G+++  VL+A   P       +        + + ++   +   YP    +   R+DT  I+ +  GV LG  I++             +I+N     L    L + + +F++G+++I+  R L + + ++V      +  +  E R+    E+ YK   YT +G+  +  +P L
Sbjct:   47 FSAALGQEVF----YITFLPFTHWNIDPNLSRRLVVIWVLVMYIGQVAKDILKWPRPSFPPVVRLEKRIIAEYGMPSTHAMAATAISFTLLISTMDRYQYPFILGLMMAVVFSTLVCLSRLYTGMHTVLDILGGVLITAVLIALTYPAWTLIDSLDSASPLFPVCVIVVPFLLCYNYPVSDYYSPTRADTTTIVAAGAGVTLGFWINHFFQLVSKPTPSLPVIQNIPP--LTTDMLVLGLTKFMVGIMLILLVRQLVQKLSLQVLFSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPML 347
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Mouse
Match: Sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:MGI Symbol;Acc:MGI:2135760])

HSP 1 Score: 85.5001 bits (210), Expect = 5.794e-18
Identity = 40/99 (40.40%), Postives = 63/99 (63.64%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSL 1243
            +GR++++ W +VMY+GQ  KD+ +  RP+SPPV+ LE  Y  EY MPSTHAM+  A+P  + L  + +  Y +   ++    W  L+  SR+Y G+HS+
Sbjct:  148 VGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPVIKLEVFYNSEYSMPSTHAMSGTAIPIAMFLLTYGRWQYPLIYGLILIPCWSSLVCLSRIYMGMHSI 246
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. UniProt/SwissProt
Match: sp|Q9BX95|SGPP1_HUMAN (Sphingosine-1-phosphate phosphatase 1 OS=Homo sapiens OX=9606 GN=SGPP1 PE=1 SV=2)

HSP 1 Score: 125.946 bits (315), Expect = 9.269e-30
Identity = 90/274 (32.85%), Postives = 148/274 (54.01%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIR-------NYEEIVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            +GR++++ W +VMY+GQ  KD+ +  RP+SPPVV LE  Y  EY MPSTHAM+  A+P  +VL  + +  Y +   ++    WC L+  SR+Y G+HS+ D+I G +  I+++A   P+++   +   T      I+  + L + +       W + R DT  ILGS  G+  GSH+ Y +        +   +  P  T+T+    I R L+G+V ++  R + K I + +  KI N+    I + RQ+   EL Y+   Y ++G  I+F +P
Sbjct:  159 VGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHLALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVTLFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITYGMVGFSITFFVP 432
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. UniProt/SwissProt
Match: sp|Q9JI99|SGPP1_MOUSE (Sphingosine-1-phosphate phosphatase 1 OS=Mus musculus OX=10090 GN=Sgpp1 PE=1 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 2.656e-26
Identity = 85/274 (31.02%), Postives = 147/274 (53.65%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEE-------IVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            +GR++++ W +VMY+GQ  KD+ +  RP+SPPV+ LE  Y  EY MPSTHAM+  A+P  + L  + +  Y +   ++    W  L+  SR+Y G+HS+ DVI G +  I+++    P ++   +   T     +I+  + L + +       W + R DT  ILGS  G+  GSH  Y +    E       + +P  T+T+    I R +LG+++++  R + K I + +  K+ ++    I + RQ+   EL Y+   Y ++G  I+F++P
Sbjct:  148 VGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPVIKLEVFYNSEYSMPSTHAMSGTAIPIAMFLLTYGRWQYPLIYGLILIPCWSSLVCLSRIYMGMHSILDVIAGFLYTILILIIFYPLVDLIDNFNQTYKYAPLIIIGLHLILGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHAAYTLGLSLEPSLHMLPLAIPPLTVTLFGKAILRIVLGMLLVLFVRDIMKKITIPLACKLSSIPCHDIRQARQHMEVELPYRYITYGMVGFSITFLVP 421
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. UniProt/SwissProt
Match: sp|Q99P55|SGPP1_RAT (Sphingosine-1-phosphate phosphatase 1 OS=Rattus norvegicus OX=10116 GN=Sgpp1 PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 3.129e-25
Identity = 82/274 (29.93%), Postives = 146/274 (53.28%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIR-------NYEEIVLPEATLTM---HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            +GR++++ W +VMY+GQ  KD+ +  RP+SPPV+ LE  Y  EY MPSTHAM+  A+P  ++L  + +  Y +   ++    W  L+  SR+Y G+HS+ DVI G +  I+++    P ++   +   T     +I+  + L + +       W + R DT  ILGS  G+  GSH  Y +        +   + +P  T+T+    I R ++G+++++  R + K + + +  K+  +    + + RQ+   EL Y+   Y  +G  I+F+IP
Sbjct:  148 VGRRLVIIWVLVMYLGQCTKDIIRWPRPASPPVIKLEIFYNSEYSMPSTHAMSGTAIPIAMILLTYGRWQYPLIYGLILIPCWSSLVCLSRIYMGMHSILDVIAGFLYTILILIIFYPLVDLIDNFNQTYKYAPLIIIGLHLILGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHAAYNLGISLDPSLHTLPLAIPPLTVTLFGKAILRVVIGMLLVLFVRDIMKKVTIPLACKLFGIPCHDLRQARQHMEVELPYRYITYGTVGFSITFLIP 421
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. UniProt/SwissProt
Match: sp|Q810K3|SGPP2_MOUSE (Sphingosine-1-phosphate phosphatase 2 OS=Mus musculus OX=10090 GN=Sgpp2 PE=1 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 3.966e-25
Identity = 85/307 (27.69%), Postives = 158/307 (51.47%), Query Frame = 2 
Query:  860 FNINLRRKLFS*LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDY-------------IIRNYEEIVLPEATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            F+  L +++F    Y  +  + ++     + R++++ W +VMYIGQ  KD+ +  RPS PPVV LE+R + EYGMPSTHAMAA A+   L+++   +  Y   L ++ +V++  L+  SRLY G+H++ D++ G+++  VL+A   P       +        + + ++   +   YP    +   R+DT  I+ +  GV LG  I++             +I+N     L    L + + +F++G+++I+  R L + + ++V      +  +  E R+    E+ YK   YT +G+  +  +P L
Sbjct:   47 FSAALGQEVF----YITFLPFTHWNIDPNLSRRLVVIWVLVMYIGQVAKDILKWPRPSFPPVVRLEKRIIAEYGMPSTHAMAATAISFTLLISTMDRYQYPFILGLMMAVVFSTLVCLSRLYTGMHTVLDILGGVLITAVLIALTYPAWTLIDSLDSASPLFPVCVIVVPFLLCYNYPVSDYYSPTRADTTTIVAAGAGVTLGFWINHFFQLVSKPTPSLPVIQNIPP--LTTDMLVLGLTKFMVGIMLILLVRQLVQKLSLQVLFSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPML 347
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. UniProt/SwissProt
Match: sp|Q8IWX5|SGPP2_HUMAN (Sphingosine-1-phosphate phosphatase 2 OS=Homo sapiens OX=9606 GN=SGPP2 PE=1 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 5.482e-25
Identity = 82/276 (29.71%), Postives = 146/276 (52.90%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLG---SHIDYIIRNYEEIV-----LPEAT---LTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            + R++++ W +VMYIGQ  KD+ +  RPSSPPVV LE+R + EYGMPSTHAMAA A+   L+++   +  Y   L ++ +V++  L+  SRLY G+H++ DV+ G+++  +L+    P       +        + + ++   +   YP    +   R+DT  IL +  GV +G   +H   ++    E +     +P  T   L + + +F +G+V+I+  R L + + ++V      +  +  E R+    E+ YK   YT +G+  +  +P L
Sbjct:  117 LSRRLIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPML 392
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. TrEMBL
Match: V4B8V5 (acidPPc domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_54296 PE=4 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 5.245e-36
Identity = 96/276 (34.78%), Postives = 150/276 (54.35%), Query Frame = 2 
Query:  935 FKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHID----YIIRN-----YEEIVLPEATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            F + IG +++L W ++MY+GQ++KD+    RP+SPPV  LE RY LEYGMPSTHAM   A+P  L++    +  Y + L ++ ++LWC L+  SR+Y G+H++ D++ G+V+  +L+  M PW E     +V    G ++  +  + + + YP    W + R DT + LG   G++LG+ I+    YII +     Y+  ++    L     R L GVV  V  RF+ K +   +   + N DPK  + +     EL YK   Y  L V  S I P
Sbjct:   38 FDTLIGLKIVLVWVLLMYVGQSLKDVICWPRPASPPVFQLEDRYALEYGMPSTHAMVGTAIPFMLLIFTVDRYEYPVLLGLIIAILWCSLVCLSRIYLGMHTIMDILAGLVLVTILLFIMVPWAETVVLYIVMTKCGGLLALLGGVVLTICYPTLDRWSTARGDTTVFLGVASGMLLGTWINFQLGYIIPSNATLPYQTAIMEFDWLKSGSLRMLTGVVATVTMRFIMKLLTFNLLCYLFNKDPKDPKTKTCLKIELPYKFCTYFGLAVCASVIAP 313
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. TrEMBL
Match: T1ISK6 (acidPPc domain-containing protein OS=Strigamia maritima OX=126957 PE=4 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 4.844e-35
Identity = 93/287 (32.40%), Postives = 158/287 (55.05%), Query Frame = 2 
Query:  911 YNHYLNFYF---KSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYE--------EIVLPEATLT-MHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            Y  +  F+F      +GR+V++ W I+MYIGQ +KD+    RP SPP V LE+++ LE+GMPSTHAM  + VP  ++     +  Y ++L  +  + WC+++  SR+Y G+H++ D+I G+++ ++L+A   P+++   H  +T     II+   IL + + YP   IW   R DT +ILG   G   GS ++Y ++           +I+ P   +  + + R  +G++++V  R  +K I   +   I  LDPK  EN Q  + EL  K   Y ++G  +S++ P
Sbjct:  110 YTSFFPFWFWNIDGAVGRRVVMIWVIIMYIGQGLKDIICWPRPFSPPAVKLEKKWALEFGMPSTHAMVGLGVPFTILYYTMYRYEYPVFLGFILCLAWCVVVCLSRIYLGMHTVLDIIGGLLLTVILLALFLPFLDHLDHFQLTNSYSPIIIVGSILFLVIFYPSGPIWTPARGDTTIILGVGAGCSFGSWLNYKLKIIHGPPIPPPYKILWPTYEMVGLTLLRSCIGILIVVGTRAFFKSISYILVCWIFRLDPKDKENNQKTFVELSCKFITYAVIGFNVSYLSP 396
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. TrEMBL
Match: A0A067R1I7 (Sphingosine-1-phosphate phosphatase 1 OS=Zootermopsis nevadensis OX=136037 GN=L798_09309 PE=4 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 1.601e-34
Identity = 97/296 (32.77%), Postives = 160/296 (54.05%), Query Frame = 2 
Query:  911 YNHYLNFYF---KSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEE--------IVLPE-ATLTMHIARFLLGVVVIVCCRFLYKP-------ILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            Y  ++ F+F      +GR+V+L W+++MYIGQ +KD+ +  RPS PPV+ L++++ LEYGMPSTHAM  V++P  ++L    +  Y + L +L ++ WC +I  SRLY G+HS+ D++VG+++A+ L+  + P ++   H ++T      IL    +C+ + YP    W   R DT M++    GV +G+  +Y +    E        I+ P    L +   R ++G   IV  R L K         L+R+ ++ L       +NRQ    EL YK   Y LLG    +++P +
Sbjct:  132 YASFIPFWFWNIDGAVGRRVVLVWTVIMYIGQGIKDVVRWPRPSCPPVIRLQKKWALEYGMPSTHAMVGVSIPLSVILYTMNRYQYSVSLGVLFAIGWCSVICLSRLYLGMHSVLDIVVGVMLALALMVPVVPLVDAMDHYLLTSSWSPAILLTAGICLVVFYPSSDRWTPTRGDTTMVVSVCVGVHIGAWTNYQLGVLSESPDSPPYAIIWPSYEMLGLSALRTVIGFCCIVATRALCKSASYATVCALLRLNSRELQRSQNSIQNRQKIIVELSYKFITYALLGFNTLYLLPSV 427
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. TrEMBL
Match: A0A226EP55 (Sphingosine-1-phosphate phosphatase 1 OS=Folsomia candida OX=158441 GN=Fcan01_04277 PE=4 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 4.026e-34
Identity = 95/304 (31.25%), Postives = 166/304 (54.61%), Query Frame = 2 
Query:  860 FNINLRRKLFS*LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDY---IIRNYE-----EIVLPE-ATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNK---YFELIYKCSMYTLLGVMISFIIP 1735
            F   L  ++F    YSC+  +  +     +GR+V++ W I+MYIGQ +KD+ +  RP  PPVV LE+++ +EYG+PSTHA+   AVP   ++    +  Y I L ++ +VLWC ++  SRLY G+HS+ D++ G+ + I +     P ++    +++    G + LF++ + +    P    W   RSDT++ILGS  G++ G  +++   IIR        +I+ P  + L + + R ++G+ +IV  R + K  L     K+L +  + D N  +K   + EL  K   Y  +G+ ++F+ P
Sbjct:  164 FGTQLGDEVF----YSCWFSFWFWNIDGAVGRRVVMMWGILMYIGQGLKDIIRWPRPMCPPVVRLEKKWEMEYGLPSTHAVVGAAVPFATIIFTSSRYQYPIELGVIGAVLWCTIVCMSRLYLGMHSVLDILAGLSLVITMFVPAIPLVDWLDSLILQNEFGGLGLFLMGVFLCFCTPGGDRWSPARSDTFVILGSCVGLIAGQWLNFQLSIIRGPPLDPPYQILWPSYSMLGLSLLRLIIGLCIIVASRAIMKSTLYTFFYKLLKITKRNDLNNASKPEIFAELSSKYLTYVFIGLHVTFVAP 463
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. TrEMBL
Match: A0A2J7R4Y5 (Sphingosine-1-phosphate phosphatase 1 OS=Cryptotermes secundus OX=105785 GN=Sgpp1 PE=4 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 5.744e-34
Identity = 101/296 (34.12%), Postives = 159/296 (53.72%), Query Frame = 2 
Query:  911 YNHYLNFYF---KSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEE--------IVLPE-ATLTMHIARFLLGVVVIVCCRFLYKP-------ILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            Y  ++ F+F      +GR+V+L W+++MYIGQ +KD+ +  RPS PPVV L++++ LEYGMPSTHAM  V++P  ++L    +  Y + L +L ++ WC +I  SRLY G+HS+ D++VGIV+A  L+  + P ++   H ++T      IL I  +C+ + YP    W   R DT M+L    GV +G+  +Y +    E        I+ P    L +   R ++G   IV  R L K         L+R+ ++ L       +NRQ    EL Y    Y LLG    +++P +
Sbjct:  135 YASFIPFWFWNIDGAVGRRVVLVWTVIMYIGQGIKDVVRWPRPSCPPVVRLQKKWALEYGMPSTHAMVGVSIPLSVILYTMNRYQYSVSLGVLFAIGWCSVICLSRLYLGMHSVLDIVVGIVLAFGLMVPVVPLVDALDHYLLTSHWSPAILLITAICLVVFYPSSDRWTPTRGDTTMVLSVCVGVHVGAWTNYQLGVLSESPDSPPYAIIWPSYEMLGLSALRTVIGFCCIVATRALCKSASYATVCTLLRLNSRELQQSQNSIKNRQKITVELSYTFITYALLGFNTVYLLPSV 430
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Cavefish
Match: sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:NCBI gene;Acc:103043414])

HSP 1 Score: 123.25 bits (308), Expect = 7.826e-30
Identity = 94/298 (31.54%), Postives = 154/298 (51.68%), Query Frame = 2 
Query:  896 LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIE--DFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATL-------------TMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPK-IDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            L Y  +  +L +     + R++++ W  VMY+GQ  KD+ +  RP+SPPVV +E  Y  EY MPSTHAM+  AVP   +L    +  Y   L ++ +  WC+L+  SR+Y G+HS+ DVIVG   +++++ F  P +E  D  H +      +II     L +     D   W + R DT  ILG+  G+ + +H++Y       IV P A++              + + RF+LGV+VI+  R + K + + +   ++ +  K + + RQN   EL Y+  +Y  +G     I+P L
Sbjct:  128 LFYISFFPFLVWNVDPLVARRLIILWVWVMYVGQCTKDVMRWPRPASPPVVKVEVFYNSEYSMPSTHAMSGTAVPLATLLLTQDRWEYPFLLGVILAFSWCILVCTSRIYMGMHSVLDVIVGFFYSLLILLFFSPALEVIDTFHQINRYAPILIISLHAGLGLFSFTLD--TWSTSRGDTAQILGTGAGIAVATHVNY---QLAVIVDPTASMLPLQLPPLSFGLVGLCLLRFVLGVLVILVTRAVMKALTIPLVCWVVGISSKDVRKARQNMQVELPYRYIVYWTVGFSAFCIVPCL 420
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Cavefish
Match: SGPP2 (sphingosine-1-phosphate phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:19953])

HSP 1 Score: 110.923 bits (276), Expect = 1.170e-25
Identity = 84/272 (30.88%), Postives = 150/272 (55.15%), Query Frame = 2 
Query:  953 RQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLP----EATLTM-----HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            R+++  W++VMYIGQ MKD+ ++ RP++PPVV LE R   EYG+PSTHAMAA A+   L+L+  +++ +   L ++ +V+   L+  SRLY G+HS  DVI GI+++ +++    P  +   ++ +      I+  ++ L +   YP+   + + R DT +ILG+  G  +G   +  +    E   P       +TM      +ARF +G+V++V  R   + I +R+      +     E R+ K  E+  K S Y+ +G++ + ++ R+
Sbjct:  147 RRLVNMWAVVMYIGQVMKDVLKLPRPTAPPVVKLEWRVDAEYGLPSTHAMAATAISFTLLLSAPERVQFQFELGLVLAVVLSGLVCLSRLYTGMHSALDVICGILISALILGISYPHWKTLDYLQLNSPISPILTLLLPLYLCYKYPELDHYSTTREDTTIILGASAGCSVGYWANQQLGVTFEPAGPFPVTLGPVTMLGIARGMARFCVGLVILVLTRQTVRSISLRLLCWNYGVALDDVEARKRKEIEVPLKYSTYSAIGLVNTVLVCRI 418
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Cavefish
Match: si:ch211-212g7.6 (sphingosine-1-phosphate phosphatase 1-like [Source:NCBI gene;Acc:103033561])

HSP 1 Score: 108.227 bits (269), Expect = 8.835e-25
Identity = 78/285 (27.37%), Postives = 145/285 (50.88%), Query Frame = 2 
Query:  920 YLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATLTM----------HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLD-PKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            +L +   + + RQV+L W  V++ GQ+ KDL    RP+SPPVV +E  Y+ EY MPS HAM   +VP  L L  + +  Y     +  ++ W  L+  SR+Y G+HS+ +VI+G + +++++A   P  +D     ++     +++ ++ + ++L+      W + R DT   L +  G  LG H+++ +    +  L    L M             R L+GV V++  R + K + + +  ++  +    + + RQN + EL Y+  +Y  + V  + ++P L
Sbjct:  147 FLMWNVDAYVSRQVILVWVWVLFFGQSTKDLVGWTRPASPPVVKVEVFYIFEYSMPSVHAMTGTSVPFCLFLLTYDRWEYPFLFGLSVAICWSFLVCISRIYMGMHSVLEVIMGFLYSLLILAAFLPVFDDIDTFYLSSRYAPLVILLLHIGLSLVAFSLDSWSTSRGDTAQALATGAGGALGCHLNHQLGLQNDPPLSSLPLKMPTIDSSLLGRSFLRLLVGVAVLLAVRAVMKAVAIPLACRMFGVPCDDVRKARQNPHVELTYRFLVYGTVAVCCACLVPLL 431
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Cavefish
Match: sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:NCBI gene;Acc:103043414])

HSP 1 Score: 89.7373 bits (221), Expect = 7.181e-19
Identity = 81/298 (27.18%), Postives = 133/298 (44.63%), Query Frame = 2 
Query:  896 LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIE--DFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATL-------------TMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPK-IDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            L Y  +  +L +     + R++++ W  VMY+GQ  KD+ +  RP+SPPVV +E  Y  EY MPSTHAM+  AVP   +L    +     +  ++    + LLI                         + F  P +E  D  H +      +II     L +     D   W + R DT  ILG+  G+ + +H++Y       IV P A++              + + RF+LGV+VI+  R + K + + +   ++ +  K + + RQN   EL Y+  +Y  +G     I+P L
Sbjct:  128 LFYISFFPFLVWNVDPLVARRLIILWVWVMYVGQCTKDVMRWPRPASPPVVKVEVFYNSEYSMPSTHAMSGTAVPLATLLLTQDR-----WEDVIVGFFYSLLI-------------------------LLFFSPALEVIDTFHQINRYAPILIISLHAGLGLFSFTLD--TWSTSRGDTAQILGTGAGIAVATHVNY---QLAVIVDPTASMLPLQLPPLSFGLVGLCLLRFVLGVLVILVTRAVMKALTIPLVCWVVGISSKDVRKARQNMQVELPYRYIVYWTVGFSAFCIVPCL 390
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Sea Lamprey
Match: si:ch211-212g7.6 (si:ch211-212g7.6 [Source:ZFIN;Acc:ZDB-GENE-030131-4695])

HSP 1 Score: 108.612 bits (270), Expect = 1.646e-25
Identity = 79/288 (27.43%), Postives = 141/288 (48.96%), Query Frame = 2 
Query:  920 YLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPE---------------ATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNL-DPKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            +L +   + + R++++ W  VM++GQ+ KDL +  RP+SPPV+ +E  Y  EYGMPSTHAM+  A+P  +      +  Y + L +  +  WCLL+  SRLY G+HS+ DV+VG++ ++ +++ + P +E    +V T +     + ++ +  AL       W + R DT  IL    GV  GS  + ++        P                  L   IAR LLG  +++  +   K   + +   + ++    +   R++   EL Y+   Y  +G   + ++P
Sbjct:  148 FLFWNVDALVARRIIMVWVWVMFLGQSAKDLLRWPRPASPPVIKVEVFYDSEYGMPSTHAMSGTALPFAIFALTLGRFEYPVVLGLALACCWCLLVCLSRLYMGMHSILDVVVGVLCSVAILSVLLPSLETLDSLVTTHMYTPDRIILVHVAAALAAFTLDGWSTSRGDTAQILAVGAGVASGSRANRLLGLLATTQAPPERLPLPVLPGLPQLPGALVRTIARVLLGSAILLATKAALKSTSIPLACWLFSIPGDDVSVARRHAQVELPYRFITYGAVGFSAACLVP 435
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Nematostella
Match: EDO44029 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWT4])

HSP 1 Score: 112.849 bits (281), Expect = 6.478e-27
Identity = 86/275 (31.27%), Postives = 150/275 (54.55%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIE-DFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEE--------IVLPEATLTMH-IARFLLGVVVIVCCRFLYKPILVRVTAKILN--LDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIP 1735
            + R+++  W + MY+GQ  KD+ Q  RP  PPV+ +E+R+  EYGMPSTHA+    +P  LV   + +  Y + + I   V WCLL+  SRLY G+H+L DV+ G+ + + ++  + P ++    + V+T  S  I +  I L M ++YP P +    ++DT M++G   GV+L S   +      +        I  P     M  ++RFLLG++++   R + K ++  V  ++L   L+PK++++    + E  ++   YT++G    FI+P
Sbjct:  121 VARRLVFLWCLFMYVGQCAKDVIQWPRPPCPPVISVEKRFECEYGMPSTHAIVGALIPFTLVYYTYDRYEYPLPVGIAVFVCWCLLVCSSRLYMGMHTLQDVLAGLALTVAMLMVVIPVLDVQLENWVLTSPSAPIFIVAIPLAMCVLYPTPPLKTETKADTIMVVGVGVGVLLASWARFAPTRVPDPYLGTPFPITFPGFDRVMAMLSRFLLGIMILAPTRSVMKALIHMVLPRVLPKYLEPKLEKD----FIEHTHRFITYTVVGFNAVFIVP 391
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Nematostella
Match: EDO29047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4R8])

HSP 1 Score: 93.5893 bits (231), Expect = 3.346e-22
Identity = 42/99 (42.42%), Postives = 62/99 (62.63%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSL 1243
            + R+++  W + MY+GQ  KD+ Q  RP  PPV+ +E+R+  EYGMPSTHA+    +P  LV   + +  Y + + I   V WCLL+  SRLY G+H+L
Sbjct:   35 VARRLVFLWCLFMYVGQCAKDVIQWPRPPCPPVISVEKRFECEYGMPSTHAIVGALIPFTLVYYTYDRYEYPLPVGIAVFVCWCLLVCSSRLYMGMHTL 133
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Nematostella
Match: EDO34697 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNL5])

HSP 1 Score: 60.077 bits (144), Expect = 1.070e-9
Identity = 35/109 (32.11%), Postives = 59/109 (54.13%), Query Frame = 2 
Query:  923 LNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLN--VHKKIPYYIYLAILSS-VLWCLLISFSRLYKGVHS 1240
            + +   + +GR +     I  Y+   +K+L  + RPS+PP+V LE      +G+PS HA+  V +P  + L   +H     + ++ + +  VLW + + FSRLY GVHS
Sbjct:   93 MTWVIDAKLGRLICFLMGIGFYVAGFVKNLLCLPRPSNPPIVPLEPSSFETWGLPSHHAVLGVLIPWYIWLYSLLHFNFSQWQFITLFAVIVLWSVSVMFSRLYLGVHS 201
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Nematostella
Match: EDO27291 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9N3])

HSP 1 Score: 47.3654 bits (111), Expect = 6.344e-6
Identity = 21/60 (35.00%), Postives = 34/60 (56.67%), Query Frame = 2 
Query:  941 STIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVP 1120
            + +GR +     I  Y+   +K+L  + RPS+PP+V LE      +G+PS HA+  V +P
Sbjct:   26 AKLGRLICFLMGIGFYVAGFVKNLLCLPRPSNPPIVPLEPSSFETWGLPSHHAVLGVLIP 85
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Medaka
Match: SGPP2 (sphingosine-1-phosphate phosphatase 2 [Source:NCBI gene;Acc:101156907])

HSP 1 Score: 129.413 bits (324), Expect = 4.264e-32
Identity = 98/279 (35.13%), Postives = 156/279 (55.91%), Query Frame = 2 
Query:  953 RQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHI-DYIIRNYEEIVLPEATLTMHI------------ARFLLGVVVIVCCRFLYKPILVRVTAKILNL---DPKIDEN-RQNKYFELIYKCSMYTLLGVMISFIIPR 1738
            R+++  W++VMYIGQ MKDL ++ RP SPPVV LE R   EYG+PSTHAMAA A+   L+L+   ++ +   + +L +     L+  SRLY G+HS+ DV+ G++++ VL+    P+ E F    +T      +   ++L ++  YP+   + + R DT  ILG   G  +G  + + + R +E    PE TL + +             RFLLGVV +V  R + K    R++ +IL L    PK D+N R+ K  E+  K + YT++G++ S ++ R
Sbjct:  125 RRLINMWTLVMYIGQVMKDLLKLPRPVSPPVVKLETRVDAEYGLPSTHAMAATAIFFTLLLSAPARVQFPFEVGLLIATTLSTLVCLSRLYTGMHSVLDVVCGVLISAVLILVTFPYWEAFDRFQLTSRISPFVALSLLLFLSYTYPELDHYSTTRGDTTTILGVCAGCSVGYWVNEQLGRTFE----PEGTLPVPVPPMTAPAVGRGACRFLLGVVALVGTRQIMK----RLSLQILYLWYKVPKSDDNARRRKEIEVPSKFTTYTVVGLVNSILVNR 395
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Medaka
Match: sgpp1 (sphingosine-1-phosphate phosphatase 1 [Source:NCBI gene;Acc:101173595])

HSP 1 Score: 126.716 bits (317), Expect = 5.664e-31
Identity = 96/306 (31.37%), Postives = 159/306 (51.96%), Query Frame = 2 
Query:  860 FNINLRRKLFS*LIYSCYNHYLNFYFKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATLTMHI----------ARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKID--ENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            F   L  +LF    Y  +  ++ +     +GR++++ W  VMY+GQ  KDL +  RP+SPPVV +E  Y  EY MPSTHAM+  A+P  L      +  Y   L    ++ WCLL+  SR+Y G+HS+ DVI G +  +VL+ F+ P +E      +T     +++  + + + L+      W + R DT  ILGS  G+ L S ++Y +    ++   +  LTM +           RF+LGV+V++  R L K + + +   ++ + P  D  + RQ+   EL Y+  +Y  +G  + F++P L
Sbjct:  137 FGTELGNELF----YIIFFPFIMWNIDVLVGRRLVMVWVWVMYLGQCTKDLLRWSRPASPPVVKVEVFYNSEYSMPSTHAMSGTAIPFSLFFMTDGRWEYPSSLGFGLALCWCLLVCSSRIYMGMHSVLDVIAGFLYTVVLLQFILPALEPVDTFNLTSRFAPLVILFLHVGLGLLSFTLDTWSTSRGDTAQILGSGAGIALASQVNYRLGLIPDLRADQVPLTMPVLSSGLVGAAMLRFVLGVLVLMVTRALMKAVTIPLVCWLVGV-PGGDTRKARQHMEVELPYRYIVYGTMGFNVLFLVPLL 437
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Medaka
Match: si:ch211-212g7.6 (sphingosine-1-phosphate phosphatase 1 [Source:NCBI gene;Acc:101166766])

HSP 1 Score: 105.916 bits (263), Expect = 4.852e-24
Identity = 80/278 (28.78%), Postives = 149/278 (53.60%), Query Frame = 2 
Query:  947 IGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIE--DFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATLTM----------HIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDP-KIDENRQNKYFELIYKCSMYTLLGVMISFIIPRL 1741
            + R++++ W+  +++GQ+ KD+ +  RP+SPPVV +E  Y  EY MPSTHAM   A+P  L +  + +  Y   L    ++ W +L+  SR+Y G+HS+ +VI G + +++++AF CP +   D ++M+      ++++  + L +     D   W + R DT   LG+  G  L SH++Y +   ++  L    LT+           + RFL+GV V++  R + K + +    ++      ++ + RQ    EL Y+  +Y+++G    F +P+L
Sbjct:  154 VSRRLIVVWAWNLFVGQSTKDMVRWSRPASPPVVKVEVFYNTEYSMPSTHAMTGTAIPFCLFMLTYGRWQYPFLLGFSVALSWSVLVCVSRVYMGMHSILEVITGFLYSLLVLAFFCPLLHKIDSYYMMGQYSPLVVLVSHVSLGLVAFSLDS--WSTSRGDTAQALGTAAGAALASHMNYQLGLLQDPPLSSLPLTLPALSAGLVLRSLLRFLIGVAVLLLTRMMMKAVTIPFLCRLFGFPADEVRQARQQMRVELPYRYIVYSVVGFSCVFFVPQL 429
[Close]
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Planmine SMEST
Match: SMESG000050348.1 (SMESG000050348.1)

HSP 1 Score: 490.73 bits (1262), Expect = 7.959e-171
Identity = 276/279 (98.92%), Postives = 277/279 (99.28%), Query Frame = 2 
Query:  935 FKSTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLXXXXXXXXXXXXXXXFMCPWIEDFHHMVVTKXXXXXXXXXXXXXXXXXYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRLSYKCDLGRLY 1771
            +  TIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLADVIVGIVVAIVLVAFMCPWIEDFHHMVVTKISGIIILFIIILCMALIYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRLSYKCDLGRLY
Sbjct:   80 YDDTIGRQVMLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAVAVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLADVIVGIVVAIVLVAFMCPWIEDFHHMVVTKISGIIILFIIILCMALIYPDPTIWKSGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATLTMHIARFLLGVVVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLGVMISFIIPRLSYKCDLGRLY 358
The following BLAST results are available for this feature:
BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SGPP11.930e-3032.85sphingosine-1-phosphate phosphatase 1 [Source:HGNC... [more]
SGPP11.930e-3032.85sphingosine-1-phosphate phosphatase 1 [Source:HGNC... [more]
SGPP21.142e-2529.71sphingosine-1-phosphate phosphatase 2 [Source:HGNC... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SGPP29.740e-3132.73sphingosine-1-phosphate phosphatase 2 [Source:NCBI... [more]
SGPP22.014e-2932.84sphingosine-1-phosphate phosphatase 2 [Source:NCBI... [more]
sgpp13.764e-2728.16sphingosine-1-phosphate phosphatase 1 [Source:ZFIN... [more]
sgpp17.536e-2728.16sphingosine-1-phosphate phosphatase 1 [Source:ZFIN... [more]
si:ch211-212g7.61.818e-2127.90si:ch211-212g7.6 [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
sgpp11.781e-2934.78sphingosine-1-phosphate phosphatase 1 [Source:NCBI... [more]
ndst46.198e-2832.97N-deacetylase/N-sulfotransferase (heparan glucosam... [more]
ndst47.338e-2832.97N-deacetylase/N-sulfotransferase (heparan glucosam... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Sgpp13.797e-2731.02sphingosine-1-phosphate phosphatase 1 [Source:MGI ... [more]
Sgpp25.670e-2627.69sphingosine-1-phosphate phosphotase 2 [Source:MGI ... [more]
Sgpp15.794e-1840.40sphingosine-1-phosphate phosphatase 1 [Source:MGI ... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9BX95|SGPP1_HUMAN9.269e-3032.85Sphingosine-1-phosphate phosphatase 1 OS=Homo sapi... [more]
sp|Q9JI99|SGPP1_MOUSE2.656e-2631.02Sphingosine-1-phosphate phosphatase 1 OS=Mus muscu... [more]
sp|Q99P55|SGPP1_RAT3.129e-2529.93Sphingosine-1-phosphate phosphatase 1 OS=Rattus no... [more]
sp|Q810K3|SGPP2_MOUSE3.966e-2527.69Sphingosine-1-phosphate phosphatase 2 OS=Mus muscu... [more]
sp|Q8IWX5|SGPP2_HUMAN5.482e-2529.71Sphingosine-1-phosphate phosphatase 2 OS=Homo sapi... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V4B8V55.245e-3634.78acidPPc domain-containing protein (Fragment) OS=Lo... [more]
T1ISK64.844e-3532.40acidPPc domain-containing protein OS=Strigamia mar... [more]
A0A067R1I71.601e-3432.77Sphingosine-1-phosphate phosphatase 1 OS=Zootermop... [more]
A0A226EP554.026e-3431.25Sphingosine-1-phosphate phosphatase 1 OS=Folsomia ... [more]
A0A2J7R4Y55.744e-3434.12Sphingosine-1-phosphate phosphatase 1 OS=Cryptoter... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
sgpp17.826e-3031.54sphingosine-1-phosphate phosphatase 1 [Source:NCBI... [more]
SGPP21.170e-2530.88sphingosine-1-phosphate phosphatase 2 [Source:HGNC... [more]
si:ch211-212g7.68.835e-2527.37sphingosine-1-phosphate phosphatase 1-like [Source... [more]
sgpp17.181e-1927.18sphingosine-1-phosphate phosphatase 1 [Source:NCBI... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:ch211-212g7.61.646e-2527.43si:ch211-212g7.6 [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO440296.478e-2731.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO290473.346e-2242.42Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO346971.070e-932.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO272916.344e-635.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SGPP24.264e-3235.13sphingosine-1-phosphate phosphatase 2 [Source:NCBI... [more]
sgpp15.664e-3131.37sphingosine-1-phosphate phosphatase 1 [Source:NCBI... [more]
si:ch211-212g7.64.852e-2428.78sphingosine-1-phosphate phosphatase 1 [Source:NCBI... [more]
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BLAST of Sphingosine-1-phosphate phosphatase 1-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000050348.17.959e-17198.92SMESG000050348.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031613 ID=SMED30031613|Name=Sphingosine-1-phosphate phosphatase 1-like|organism=Schmidtea mediterranea sexual|type=transcript|length=1871bp
GATTTTTACATGTGCAATAAATATATTTACAAAATCAATAAAACCGTGTA
ATGAAAGTTTAGTTTGAAAATCCCCCCCCGAAATTTTTTTCTGTGTATGC
CCTTGTATATATTACCAACATTTACAATTACAAAAAATGAGTCAAGATTA
ACGTTTTTATACGGACATTAACATGCTTTAATAACATTGTTTAATTGATG
AATTATCAAAAGCTGTCTGAATGACACTTTAGCTGAAACAAAAATTGCTC
CCATCTGACCTCGATCCACATGACAAATTAATTTTTTTTAATGAAGCAAA
TTCCCACATTATTACTCACGCCAACCATCACAGTTCTTTTTATCTTTGTT
TTTCAAAAAATAGTCAATTGCTCATCTGTTCTAGGCGAAATTTAATATTG
TCTTTTCTAACTGCTTGTCACAATTCACAGGTATTATTTCTGGCTCGTGT
GATAAGAAAATATTTAGTCTTATTTTAGATAGAAAAATTCCATTAAATAA
TTTGAGAGTGAATTCAGTGTGTTTTGGAATGATTGTTTGATAGATTTGAA
TGACAGGTTTTTCAATAGATGAATTTAAAGATGTGACTACTCACTTATTG
AATATCCATTACGCGCATCAGACTTGTTCAGTCAATGGCTTCTTCTATGG
GGATTCAAGAAAAGTATTTATATTCCCGAAAATGTTTTTTGCATCATTAA
ATCGAAATATATGTAATTGTACACAAATGAAAAATGTGCTAGTTATTATA
GAAATAAAACAAATTTTGACTACTAGAAACACTATTTTATACCAGCTGGT
CCATAAACAATTTTTGAAGTAAAATTCAATCGACACTATTATCATGCAAA
CACATGTGATTTAATATAAATTTAAGACGGAAATTATTTAGCTAGTTAAT
ATATTCTTGTTATAATCATTATTTGAACTTTTATTTCAAAAGTACAATCG
GTCGTCAAGTAATGCTATATTGGAGTATTGTTATGTATATCGGTCAAGCT
ATGAAAGATCTCTTTCAAATGGATCGGCCTTCCTCACCGCCAGTGGTGAT
ACTTGAACAGCGATATTTATTAGAATATGGAATGCCTTCCACTCACGCTA
TGGCAGCTGTTGCTGTCCCTGCTGGTTTAGTTTTGAATGTCCATAAAAAA
ATACCTTATTATATCTATTTGGCAATTTTATCATCGGTGCTCTGGTGTCT
TTTAATTAGCTTCAGTCGCTTGTATAAAGGCGTGCATAGTTTAGCGGATG
TAATAGTCGGTATTGTTGTTGCAATAGTTTTAGTTGCATTTATGTGTCCT
TGGATTGAAGATTTTCATCATATGGTCGTCACGAAAATCAGTGGAATTAT
AATTCTTTTCATTATTATTCTTTGCATGGCATTGATTTATCCCGATCCAA
CAATTTGGAAAAGTGGTCGCAGTGATACATATATGATACTTGGTAGCATA
TTCGGTGTAATGCTGGGGTCTCATATCGACTACATTATACGAAATTATGA
AGAAATTGTTTTACCTGAAGCGACATTGACTATGCACATTGCTCGATTTT
TGTTAGGAGTTGTCGTGATTGTTTGCTGTAGGTTTCTTTACAAACCCATT
CTGGTTCGTGTCACTGCGAAAATATTGAATCTAGATCCAAAAATCGATGA
GAACAGACAAAACAAATACTTCGAATTGATATACAAATGCTCAATGTATA
CTCTCTTAGGTGTTATGATATCTTTTATAATTCCTCGATTATCCTATAAA
TGTGATTTGGGAAGATTGTATTAATAGCCTATTGTTAAAACTTGGTATTT
TTATTATATGAATGGTATCGAATGTATTTTCTAATCGAGTTATTGCAAAA
TTGATTTTTTATAAAATTGAT
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protein sequence of SMED30031613-orf-1

>SMED30031613-orf-1 ID=SMED30031613-orf-1|Name=SMED30031613-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=271bp
MLYWSIVMYIGQAMKDLFQMDRPSSPPVVILEQRYLLEYGMPSTHAMAAV
AVPAGLVLNVHKKIPYYIYLAILSSVLWCLLISFSRLYKGVHSLADVIVG
IVVAIVLVAFMCPWIEDFHHMVVTKISGIIILFIIILCMALIYPDPTIWK
SGRSDTYMILGSIFGVMLGSHIDYIIRNYEEIVLPEATLTMHIARFLLGV
VVIVCCRFLYKPILVRVTAKILNLDPKIDENRQNKYFELIYKCSMYTLLG
VMISFIIPRLSYKCDLGRLY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR036938P_Acid_Pase_2/haloperoxi_sf
IPR000326P_Acid_Pase_2/haloperoxidase
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000326Phosphatidic acid phosphatase type 2/haloperoxidaseSMARTSM00014acid_phosph_2coord: 1..112
e-value: 2.7E-5
score: 33.6
IPR000326Phosphatidic acid phosphatase type 2/haloperoxidasePFAMPF01569PAP2coord: 7..117
e-value: 2.3E-15
score: 56.5
NoneNo IPR availableGENE3DG3DSA:1.20.144.10coord: 20..127
e-value: 3.1E-13
score: 51.3
NoneNo IPR availablePANTHERPTHR14969SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASEcoord: 3..262
NoneNo IPR availablePANTHERPTHR14969:SF14SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2coord: 3..262
NoneNo IPR availableTMHMMTMhelixcoord: 64..83
NoneNo IPR availableTMHMMTMhelixcoord: 191..210
NoneNo IPR availableTMHMMTMhelixcoord: 157..176
NoneNo IPR availableTMHMMTMhelixcoord: 122..144
NoneNo IPR availableTMHMMTMhelixcoord: 90..112
NoneNo IPR availableTMHMMTMhelixcoord: 239..261
IPR036938Phosphatidic acid phosphatase type 2/haloperoxidase superfamilySUPERFAMILYSSF48317Acid phosphatase/Vanadium-dependent haloperoxidasecoord: 7..114