Histone-lysine N-methyltransferase

Overview
NameHistone-lysine N-methyltransferase
Smed IDSMED30031607
Length (bp)1811
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Histone-lysine N-methyltransferase (SMED30031607) t-SNE clustered cells

Violin plots show distribution of expression levels for Histone-lysine N-methyltransferase (SMED30031607) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Histone-lysine N-methyltransferase (SMED30031607) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Histone-lysine N-methyltransferase (SMED30031607) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031607

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30031607SMESG000074842.1 Contig1168newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30031607SMESG000074842.1 Contig1168uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30031607SMESG000074842.1 Contig1168newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30031607SMESG000074842.1 Contig1168uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30031607SMESG000074842.1 Contig1168newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30031607SMESG000074842.1 Contig1168uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30031607SMESG000037819.1 Contig1168newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30031607SMESG000037819.1 Contig1168uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30031607SMESG000037819.1 Contig1168newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30031607SMESG000037819.1 Contig1168uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30031607SMESG000037819.1 Contig1168newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30031607SMESG000037819.1 Contig1168uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
X1 cellSMED30031607SMESG000074842.1 SmedASXL_015702SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Human
Match: SUV39H1 (suppressor of variegation 3-9 homolog 1 [Source:HGNC Symbol;Acc:HGNC:11479])

HSP 1 Score: 256.914 bits (655), Expect = 6.363e-79
Identity = 162/430 (37.67%), Postives = 229/430 (53.26%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYP-LFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++EVE + D  +   ++ YLVKW+ +     TWEP++NL  C    +++ K  LE               EL+ +  RS T     P H+   L   L  K+ +R                      +AL  WE  +N     L ++TVEN VD +GPP  F +I +Y        +   + C C          C   +S+H     Y   G+V  + G+PIYECNS C C  +CP RVVQ+G++  L IFRT + RGWG++TL KI + +F+MEY+GEI+  +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R I+AGEELTFDY M     D +             ++ N    AG   +   ++  R+ C C +E CRK+L+
Sbjct:   42 DFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNL-KCVRILKQFHK-DLER--------------ELLRRHHRSKT-----PRHLDPSLANYLVQKAKQR----------------------RALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLH--KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTR----------MDSNFGL-AGLPGSPKKRV--RIECKCGTESCRKYLF 412
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Human
Match: SUV39H1 (suppressor of variegation 3-9 homolog 1 [Source:HGNC Symbol;Acc:HGNC:11479])

HSP 1 Score: 256.914 bits (655), Expect = 7.664e-79
Identity = 162/430 (37.67%), Postives = 229/430 (53.26%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYP-LFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++EVE + D  +   ++ YLVKW+ +     TWEP++NL  C    +++ K  LE               EL+ +  RS T     P H+   L   L  K+ +R                      +AL  WE  +N     L ++TVEN VD +GPP  F +I +Y        +   + C C          C   +S+H     Y   G+V  + G+PIYECNS C C  +CP RVVQ+G++  L IFRT + RGWG++TL KI + +F+MEY+GEI+  +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R I+AGEELTFDY M     D +             ++ N    AG   +   ++  R+ C C +E CRK+L+
Sbjct:   53 DFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNL-KCVRILKQFHK-DLER--------------ELLRRHHRSKT-----PRHLDPSLANYLVQKAKQR----------------------RALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLH--KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTR----------MDSNFGL-AGLPGSPKKRV--RIECKCGTESCRKYLF 423
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Human
Match: SUV39H2 (suppressor of variegation 3-9 homolog 2 [Source:HGNC Symbol;Acc:HGNC:17287])

HSP 1 Score: 250.751 bits (639), Expect = 1.287e-76
Identity = 149/372 (40.05%), Postives = 200/372 (53.76%), Query Frame = 1 
Query:  226 YEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETY-PLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGA 1332
            YEVE + D     + + YLVKWK W     TWEP +NL                             K  L+ Q F +           + YL  + + K+   K N+    P      +  +  + AL  W+  +N        + VENTVD EGPP DF +I +Y  +  I + ++    C CT      +K C +  G    Y    ++    G PIYECNS C C  +CP R+VQ+G +  L IFRT N RGWG+KTL KI R +F+MEY+GE++  +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD R+PRIA F+ R I AGEELTFDY M G+
Sbjct:   47 YEVEYLCDYKVVKDMEYYLVKWKGWPDSTNTWEPLQNL-----------------------------KCPLLLQQFSN---------DKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFF--QKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESD-EFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGS 377
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Human
Match: SUV39H2 (suppressor of variegation 3-9 homolog 2 [Source:HGNC Symbol;Acc:HGNC:17287])

HSP 1 Score: 245.358 bits (625), Expect = 2.688e-75
Identity = 144/355 (40.56%), Postives = 192/355 (54.08%), Query Frame = 1 
Query:  277 YLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETY-PLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGA 1332
            YLVKWK W     TWEP +NL                             K  L+ Q F +           + YL  + + K+   K N+    P      +  +  + AL  W+  +N        + VENTVD EGPP DF +I +Y  +  I + ++    C CT      +K C +  G    Y    ++    G PIYECNS C C  +CP R+VQ+G +  L IFRT N RGWG+KTL KI R +F+MEY+GE++  +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD R+PRIA F+ R I AGEELTFDY M G+
Sbjct:    4 YLVKWKGWPDSTNTWEPLQNL-----------------------------KCPLLLQQFSN---------DKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFF--QKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESD-EFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGS 317
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Human
Match: EHMT1 (euchromatic histone lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24650])

HSP 1 Score: 160.229 bits (404), Expect = 1.763e-40
Identity = 93/240 (38.75%), Postives = 141/240 (58.75%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFIT-DYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHG--GDPP----YTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            I   Y    +   N VD+E  P ++++++ + V+S + I  +     YC   CID   DCSS +   G       Y   G+++P+F +     I+ECN ACSC  NC  RVVQ G++ +L+++RT++ GWG+++L  I  G F+ EY+GE+++  EA+ R      +  +YLFDLD      + +DA   GN+S FINH C PN+    VF+ + D+R PRIAFF+ R I+AGE+L FDY
Sbjct:  983 IARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCV--CID---DCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVR------EEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDY 1211
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Celegans
Match: set-23 (Probable histone-lysine N-methyltransferase set-23 [Source:UniProtKB/Swiss-Prot;Acc:Q95Y12])

HSP 1 Score: 107.842 bits (268), Expect = 3.873e-26
Identity = 82/251 (32.67%), Postives = 111/251 (44.22%), Query Frame = 1 
Query:  763 ACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDL---NCPYRVVQRGVKLQLKIFRT--KNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLY-DQQNLTYLFDLDFAGDPEFT-VDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFL 1494
             C C   C  +   CS +      YTV GK I K    + EC+  C+C L   +C  RVVQ G + +L+IF T    +G+G++   +I  G F+ EY GE +   E E R + +    N T      F G P  T VD   +GN+  F+NHSC PN     + +  L   +P    FA RDI  GEEL +DY                                     S+++   R  CLCKSEKCRK+L
Sbjct:   26 GCNCEAEC-SSAAGCSCLINKIDNYTVDGK-INKSSELLIECSDQCACILLPTSCRNRVVQCGPQKKLEIFSTCEMAKGFGVRAGEQIAAGEFVCEYAGECIGEQEVERRCREFRGDDNYTLTLKEFFGGKPVKTFVDPRLRGNIGRFLNHSCEPNCE---IILARLGRMIPAAGIFAKRDIVRGEELCYDY-----------------------------------GHSAIEGENRKLCLCKSEKCRKYL 236
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Celegans
Match: set-11 (SET (Trithorax/polycomb) domain containing [Source:UniProtKB/TrEMBL;Acc:O17186])

HSP 1 Score: 101.679 bits (252), Expect = 4.670e-23
Identity = 75/251 (29.88%), Postives = 107/251 (42.63%), Query Frame = 1 
Query:  748 SDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIY----ECNSACSCDLNCPYRVVQRGVKLQLKIF-RTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCR 1485
            + P   C C   C  N +  S + G        G  +    + ++    ECN  C+C L C  RV Q+G    ++IF R    GWG++    I  G FI EY GE++  +EA +R       + T+LF+    G    T+DA   GN + FINHSC PN+    +  +   I++  + FF  + I+ GEELT DY    A   NK                                  + PCLCKS +CR
Sbjct:  158 ASPTFMCQCAGQCSTNCECSSGVFG-------EGGTVENMELLMWDTVRECNEYCNCALWCGNRVAQKGAMYPVEIFARDPWCGWGVRASVDIAFGTFIGEYAGELIDDEEAMDR------HDSTFLFETK-VGSETLTIDAKYSGNYTRFINHSCAPNVKVANISWDYDKIQLIHMCFFTDKAIRKGEELTIDY--GEAWWANK----------------------------------KFPCLCKSSECR 358
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Celegans
Match: set-25 (Histone-lysine N-methyltransferase set-25 [Source:UniProtKB/Swiss-Prot;Acc:G5EEU2])

HSP 1 Score: 95.9005 bits (237), Expect = 2.189e-20
Identity = 53/168 (31.55%), Postives = 84/168 (50.00%), Query Frame = 1 
Query:  877 IYECNSACSCDLNCPYRVVQRGVKLQLKI-FRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAV-------------DEAEERGKLYDQQNLTYLFDLDF-AGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNL--DIRMPRIAFFAARDIKAGEELTFDYMMTG 1329
            + EC+ AC C L+CP R +QRG +  L + +    +G+G++    I  G  + EY G++  +             D+ EE+      + +   +D  F A D +  + A K GN+S FINHSC+P+     V+      D  +PR+A +A +DI  GEE+T  Y   G
Sbjct:  523 VMECSDACGCSLDCPRRSLQRGQQHPLAVYYEGPEKGFGVRAAANIKAGELVCEYTGDVTLLPTSDPVASSSTKTDDGEEQENPEAPERVDSSYDAAFNAMDTKIIISAKKTGNISRFINHSCDPSSVFVEVYSRRFEEDPLIPRVAVYAIKDIALGEEITIAYYEPG 690
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Celegans
Match: set-23 (Probable histone-lysine N-methyltransferase set-23 [Source:UniProtKB/Swiss-Prot;Acc:Q95Y12])

HSP 1 Score: 83.5741 bits (205), Expect = 1.236e-18
Identity = 55/174 (31.61%), Postives = 75/174 (43.10%), Query Frame = 1 
Query:  979 RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLY-DQQNLTYLFDLDFAGDPEFT-VDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFL 1494
            +G+G++   +I  G F+ EY GE +   E E R + +    N T      F G P  T VD   +GN+  F+NHSC PN     + +  L   +P    FA RDI  GEEL +DY                                     S+++   R  CLCKSEKCRK+L
Sbjct:   16 KGFGVRAGEQIAAGEFVCEYAGECIGEQEVERRCREFRGDDNYTLTLKEFFGGKPVKTFVDPRLRGNIGRFLNHSCEPNCE---IILARLGRMIPAAGIFAKRDIVRGEELCYDY-----------------------------------GHSAIEGENRKLCLCKSEKCRKYL 151
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Celegans
Match: met-1 (Histone-lysine N-methyltransferase [Source:UniProtKB/TrEMBL;Acc:A4LBC2])

HSP 1 Score: 88.1965 bits (217), Expect = 7.727e-18
Identity = 54/152 (35.53%), Postives = 79/152 (51.97%), Query Frame = 1 
Query:  877 IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLY---DQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYM 1320
            + EC S  SC + C  +   +     ++ F T   +G GL+ +  I +G FI+EY+GE+V  D+ E+R   Y    +    YL D        +T+DA   GN S F+NHSC+PN       +      + R+ FF+ R IKAGEE+TFDY 
Sbjct:  661 LTECPS--SCQVKCKNQRFAKKKYAAVEAFHTGTAKGCGLRAVKDIKKGRFIIEYIGEVVERDDYEKRKTKYAADKKHKHHYLCDTGV-----YTIDATVYGNPSRFVNHSCDPNAICEKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDYQ 805
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Fly
Match: Su(var)3-9 (gene:FBgn0263755 transcript:FBtr0310385)

HSP 1 Score: 177.948 bits (450), Expect = 7.759e-48
Identity = 153/455 (33.63%), Postives = 222/455 (48.79%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQ-------------SKSTKR-KKNSDISLPNK--KRKKIVLSTIKKALSDWETLINET-YPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPP------IACYCTT---SCIDNKKDCSSIHGGDPPY-TVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDF--AGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            EY VE I     +  + V+ VKW  +H    TWE   N+ +C     E EK  +E  +  + I   +   EL  Q+       N+  + V  Y P  LQ             S+S +  +K  + +L +   KR + V       L+ +E  +N    P   + VEN +D +    +F +I D +     I  D P      + C CT     C  + K C+   G    Y   T ++  + G  IYECNS CSCD +C  R+VQ G ++ L +F+T N  GWG++  T + +G F+ EY+GEI+  DEA ERGK YD    TYLFDLD+  A D E+T+DA   GN+SHFINHSC+PN+     +I +L++ +P + FF  R IKAGEEL+FDY+     +DN+                +  YE       +L    RV C C ++ CRK L+
Sbjct:  218 EYVVERIECVEMDQYQPVFFVKWLGYHDSENTWESLANVADCA----EMEK-FVERHQQLYEIYIAKITTELEKQLEALPLMENITVAEVDAYEPLNLQIDLILLAQYRAAGSRSQREPQKIGERALKSMQIKRAQFVRRKQLADLALFEKRMNHVEKPSPPIRVENNIDLDTIDSNFMYIHDNI-----IGKDVPKPEAGIVGCKCTEDTEECTASTKCCARFAGELFAYERSTRRLRLRPGSAIYECNSRCSCDSSCSNRLVQHGRQVPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEIITSDEANERGKAYDDNGRTYLFDLDYNTAQDSEYTIDAANYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDYIR----ADNE----------------DVPYE-------NLSTAVRVECRCGADNCRKVLF 635
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Fly
Match: G9a (gene:FBgn0040372 transcript:FBtr0332992)

HSP 1 Score: 130.183 bits (326), Expect = 5.802e-31
Identity = 75/217 (34.56%), Postives = 113/217 (52.07%), Query Frame = 1 
Query:  700 DFQFITDYVSSSIEIHSDPPIA----CYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFG----VPIYECNSACSCD-LNCPYRVVQRGVKLQLKIFRTKN--RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            DF+++T  +     +  D  ++    C C  SC  ++  C+     +  YT   ++   F       I+ECN  C C+ L+C  RVVQ G +  L+I   ++  +GWG++ L  + +G F+  Y GEI+   EA+ R       + +Y FDLD        +DA   GN++ F NHSC PN+    VF  + D R P+IAFF+ RDI AGEE+ FDY
Sbjct: 1392 DFRYVTQCIIQQNSVQIDRRVSQMRICSCLDSCSSDRCQCNGASSQNW-YTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADRR------TDDSYYFDLDNG----HCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDY 1597
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Fly
Match: G9a (gene:FBgn0040372 transcript:FBtr0070063)

HSP 1 Score: 130.183 bits (326), Expect = 5.879e-31
Identity = 75/217 (34.56%), Postives = 113/217 (52.07%), Query Frame = 1 
Query:  700 DFQFITDYVSSSIEIHSDPPIA----CYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFG----VPIYECNSACSCD-LNCPYRVVQRGVKLQLKIFRTKN--RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            DF+++T  +     +  D  ++    C C  SC  ++  C+     +  YT   ++   F       I+ECN  C C+ L+C  RVVQ G +  L+I   ++  +GWG++ L  + +G F+  Y GEI+   EA+ R       + +Y FDLD        +DA   GN++ F NHSC PN+    VF  + D R P+IAFF+ RDI AGEE+ FDY
Sbjct: 1372 DFRYVTQCIIQQNSVQIDRRVSQMRICSCLDSCSSDRCQCNGASSQNW-YTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEILTAMEADRR------TDDSYYFDLDNG----HCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDY 1577
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Fly
Match: CG4565 (gene:FBgn0037841 transcript:FBtr0113216)

HSP 1 Score: 110.923 bits (276), Expect = 6.261e-27
Identity = 88/276 (31.88%), Postives = 132/276 (47.83%), Query Frame = 1 
Query:  700 DFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGK--VIPKFGVPIYECNSACSCDLN-CPYRVVQRGVKLQLKIFRTKNRGW-GLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNL---TYLFDL-DFAGDPE---FTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFL 1494
            +F+F+ D  +S +    +P   C+C  +C +N + C+  HGG   +T  G   ++     P+ ECN  C C  N C  R+V  G +  L+IF +   G  GL+T  KI +G +I EY GE++ V EA  R +L+D + L    Y+  L ++  D +     VD  ++GN+  ++NHSC PN     V I   D  +P+I  FAARDI A EEL F Y   G                        +Y+         ++TG   CLC + KC  F+
Sbjct:   34 EFKFLADEYNSVL---LNP---CHCKGAC-ENSEVCA--HGGQYEFTEDGSELILRNSANPVIECNDMCKCCRNTCSNRLVYSGPRKHLEIFDSPVYGSKGLRTTAKITKGGYICEYAGELLTVPEA--RSRLHDNEKLGLMNYILVLNEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRI---DCPIPKIGIFAARDIAAKEELCFHYGGEG------------------------QYK---------KMTGGKTCLCGASKCTGFM 262
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Fly
Match: E(z) (gene:FBgn0000629 transcript:FBtr0334067)

HSP 1 Score: 100.138 bits (248), Expect = 1.131e-21
Identity = 66/191 (34.55%), Postives = 89/191 (46.60%), Query Frame = 1 
Query:  763 ACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCD------LNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
             C C   C  N K C       P Y    +  P           AC  D      + C    VQRG+   L +  +   GWG+       +  FI EY GEI++ DEA+ RGK+YD+   ++LF+L    + +F VDA +KGN   F NHS NPN  ++ + +        RI  FA R I+ GEEL FDY
Sbjct:  579 GCRCKAQC--NTKQC-------PCYLAVRECDPDLC-------QACGADQFKLTKITCKNVCVQRGLHKHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNL----NNDFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDH----RIGIFAKRAIQPGEELFFDY 745
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Zebrafish
Match: suv39h1b (suppressor of variegation 3-9 homolog 1b [Source:ZFIN;Acc:ZDB-GENE-030131-5105])

HSP 1 Score: 246.514 bits (628), Expect = 5.559e-75
Identity = 158/432 (36.57%), Postives = 222/432 (51.39%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNL--INCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINE--TYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKD--CSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            +Y+ + I D   +  +++YLVKWK +     TWEP++NL  +N   +F E                      E+  Q  RS     + P+ V         +  T+R K                  +++ L  WET +N   T+  + ++V N VD EGPP  F +I DY      + ++  + C CT  C+ +  +  C+        Y   G+V  + G+PIYECN  C C  +C  RVVQRG++  L IFRT N RGWG++T+ +I +  F+MEY+GEI+  +EAE RG +YD++  TYLFDLD+  D E+TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R IKAGEELTFDY M     D +  +           N       GS          RV C C    CRK+L+
Sbjct:   52 DYKRKVITDGKRQTVQELYLVKWKGYPESRNTWEPRRNLRCVNLLSQFWE------------------DLNAEMQRQNKRSAPR-RLDPATV---------THLTQRAK------------------LRQTLKQWETHLNSLGTHKGY-ISVRNQVDLEGPPKSFTYINDYKVGDGILLNEVSVGCECT-DCLASPVEGCCAGASQHKFAYNELGQVRIRPGLPIYECNKRCRCGPDCSNRVVQRGIRYSLCIFRTDNGRGWGVRTMERIRKNTFVMEYVGEIITTEEAERRGHVYDKEGATYLFDLDYV-DDEYTVDAAHYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRGIKAGEELTFDYNMKIDPVDAESTK--------MDTNFGVMGLPGSPKKRM-----RVECKCGVATCRKYLF 421
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Zebrafish
Match: suv39h1b (suppressor of variegation 3-9 homolog 1b [Source:ZFIN;Acc:ZDB-GENE-030131-5105])

HSP 1 Score: 246.128 bits (627), Expect = 1.016e-74
Identity = 158/432 (36.57%), Postives = 222/432 (51.39%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNL--INCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINE--TYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKD--CSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            +Y+ + I D   +  +++YLVKWK +     TWEP++NL  +N   +F E                      E+  Q  RS     + P+ V         +  T+R K                  +++ L  WET +N   T+  + ++V N VD EGPP  F +I DY      + ++  + C CT  C+ +  +  C+        Y   G+V  + G+PIYECN  C C  +C  RVVQRG++  L IFRT N RGWG++T+ +I +  F+MEY+GEI+  +EAE RG +YD++  TYLFDLD+  D E+TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R IKAGEELTFDY M     D +  +           N       GS          RV C C    CRK+L+
Sbjct:   62 DYKRKVITDGKRQTVQELYLVKWKGYPESRNTWEPRRNLRCVNLLSQFWE------------------DLNAEMQRQNKRSAPR-RLDPATV---------THLTQRAK------------------LRQTLKQWETHLNSLGTHKGY-ISVRNQVDLEGPPKSFTYINDYKVGDGILLNEVSVGCECT-DCLASPVEGCCAGASQHKFAYNELGQVRIRPGLPIYECNKRCRCGPDCSNRVVQRGIRYSLCIFRTDNGRGWGVRTMERIRKNTFVMEYVGEIITTEEAERRGHVYDKEGATYLFDLDYV-DDEYTVDAAHYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRGIKAGEELTFDYNMKIDPVDAESTK--------MDTNFGVMGLPGSPKKRM-----RVECKCGVATCRKYLF 431
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Zebrafish
Match: suv39h1a (suppressor of variegation 3-9 homolog 1a [Source:NCBI gene;Acc:445198])

HSP 1 Score: 239.58 bits (610), Expect = 1.736e-72
Identity = 153/430 (35.58%), Postives = 228/430 (53.02%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINET-YPLFKVTVENTVDTEGPPLDFQFITD-YVSSSIEIHSDPPIACYCTTSCIDNKKD--CSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            +YEVE + +  +    + +LVKWK +     TWEP KNL  C     ++ K    + K   ++   +P                +  + +   + + L+ K+T+R +                      L  WE L+N+T +   ++ V N VD +GPP +F +I +  +   +++++   + C C   C+    D  C  +      Y  + +V    GVPIYECNS C C  +C  RVVQRG++  L IF+T N RGWG++TL +I + +F+MEYLGEI+  DEAE+RG LYD+Q +TYLFDLD+  D  +T+DA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIA FA R IKAGEELTFDY MT    D +  +  +  +            AG E +   ++   + C C    CRK+L+
Sbjct:   42 DYEVEYLCNYKKHKGREFFLVKWKGYEESENTWEPLKNL-KCPILLHQFRK----DMKAA-LLQANEP----------------LDSASLSGPIISFLRQKATQRIR----------------------LKKWEDLMNQTCWHKGRIFVSNEVDMDGPPKNFTYINENKLGKGVDMNA-VIVGCECE-DCVSQPVDGCCPGLLKFRRAYNESRRVKVMPGVPIYECNSKCRCGPDCANRVVQRGIQYDLCIFKTDNGRGWGVRTLQRINKNSFVMEYLGEIITTDEAEQRGVLYDKQGVTYLFDLDYVDDV-YTIDAAHYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIALFAKRGIKAGEELTFDYKMTVDPVDAESTKMDLDFS-----------RAGIEGSPIKRV--HMECKCGVRNCRKYLF 411
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Zebrafish
Match: ehmt1a (euchromatic histone-lysine N-methyltransferase 1a [Source:ZFIN;Acc:ZDB-GENE-040724-44])

HSP 1 Score: 148.288 bits (373), Expect = 1.576e-39
Identity = 87/236 (36.86%), Postives = 132/236 (55.93%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGG---DPPYTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            ++  Y    V   N VD E  P +F++I +   +S +++ D  I      SC D+    S I G       Y   G+++ +F       ++ECN ACSC   C  RV+Q G++L+L++FRT+  GWG++TL  I  G F+ E+ GEI++  EA  R      +N +Y+F+LD      + +D    GN+S F+NH C PN+    VF  + D+R PRIAFFA++ I+AG+EL FDY
Sbjct:   30 VSRGYEDIPVPCVNGVDHEPCPSNFKYIPENCFTS-QVNIDENIKHLQHCSCKDDCASSSCICGQLSMHCWYGKDGRLLKEFCRDDPPFLFECNHACSCWRTCRNRVIQNGLRLRLQVFRTERMGWGVRTLQDIPEGGFVCEFAGEIISDGEANIR------ENDSYMFNLDNKVGEAYCIDGQFYGNVSRFMNHLCEPNLFPVRVFTKHQDMRFPRIAFFASKHIQAGDELGFDY 258
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Zebrafish
Match: ehmt1b (euchromatic histone-lysine N-methyltransferase 1b [Source:ZFIN;Acc:ZDB-GENE-080515-3])

HSP 1 Score: 154.836 bits (390), Expect = 5.652e-39
Identity = 92/237 (38.82%), Postives = 133/237 (56.12%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPP---YTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            I   Y    V   N VD+E  P +++++ D  V+S + I  +     YC   C D+    S + G       Y    +++P+F       I+ECN ACSC   C  RVVQ G++ +L++F+T+  GWG+KTL  I +G F+ EY+GEI++  EA+ R      +N +YLF LD      + VDA   GN+S FINH C PN+    VF ++ D+R P IAFFA ++I AG+EL FDY
Sbjct:  720 IARGYEKVPVPCVNAVDSEPCPDNYKYVPDSCVTSPLNIDKNITHLQYCV--CKDDCSSASCMCGQLSLRCWYDKESRLLPEFSNEEPPLIFECNHACSCWRTCKNRVVQNGLRTRLQLFKTQMMGWGVKTLQDIPQGTFVCEYVGEIISDAEADVR------ENDSYLFSLDSKVGDMYCVDARFYGNISRFINHHCEPNLLPCRVFTSHQDLRFPHIAFFACKNISAGDELGFDY 948
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Xenopus
Match: suv39h2 (suppressor of variegation 3-9 homolog 2 [Source:NCBI gene;Acc:549262])

HSP 1 Score: 251.136 bits (640), Expect = 7.996e-77
Identity = 168/437 (38.44%), Postives = 222/437 (50.80%), Query Frame = 1 
Query:  226 YEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRK---KNSDISLPNKKRKKIVLSTIKKALSDWETLIN----ETYPLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITG-----RVPCLCKSEKCRKFL 1494
            YEVE + D   E   + + VKWK W     TWEP +NL  C                             L+ Q +          S +Y Y   L  +K    K   K+ D SL +   KK   +  + AL  WE  +N     +  LF   VENTVD EGPP+DF +I DY  S  +    +  + C C+  C   K  C +  G    Y    ++    G PIYECNS C C  +CP RVVQ+G    L IFRT N RGWG+KTL KI + +F+MEY+GE++  +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD+R+PRIA F+ R+IKAGEELTFDY M G                           +G  ST S+ ++      R+ C C +  CR +L
Sbjct:   43 YEVEYLCDYRIEKGVEKFFVKWKGWPESCNTWEPTRNL-KCP---------------------------TLLKQFY----------SDLYNYFCALKPNKKGFLKNSIKSLDPSLSDYIVKK---AKQRIALRRWEEELNRKKTHSGTLF---VENTVDLEGPPMDFYYINDYKASPGVNTLGEAIVGCDCS-DCFKGKC-CPTEAGVLFAYNEHRQIKIPPGRPIYECNSRCKCGPDCPNRVVQKGPPYSLCIFRTDNGRGWGVKTLQKIKKNSFVMEYVGEVITSEEAERRGQQYDSRGITYLFDLDYEAD-EFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDVRLPRIALFSTRNIKAGEELTFDYQMKG---------------------------SGDLSTDSIDMSPAKKRVRIACKCGAATCRGYL 405
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Xenopus
Match: suv39h2 (suppressor of variegation 3-9 homolog 2 [Source:NCBI gene;Acc:549262])

HSP 1 Score: 247.284 bits (630), Expect = 5.393e-75
Identity = 157/375 (41.87%), Postives = 204/375 (54.40%), Query Frame = 1 
Query:  226 YEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRK---KNSDISLPNKKRKKIVLSTIKKALSDWETLIN----ETYPLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMM 1323
            YEVE + D   E   + + VKWK W     TWEP +NL  C                             L+ Q +          S +Y Y   L  +K    K   K+ D SL +   KK   +  + AL  WE  +N     +  LF   VENTVD EGPP+DF +I DY  S  +    +  + C C+  C   K  C +  G    Y    ++    G PIYECNS C C  +CP RVVQ+G    L IFRT N RGWG+KTL KI + +F+MEY+GE++  +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD+R+PRIA F+ R+IKAGEELTFDY M
Sbjct:   43 YEVEYLCDYRIEKGVEKFFVKWKGWPESCNTWEPTRNL-KCP---------------------------TLLKQFY----------SDLYNYFCALKPNKKGFLKNSIKSLDPSLSDYIVKK---AKQRIALRRWEEELNRKKTHSGTLF---VENTVDLEGPPMDFYYINDYKASPGVNTLGEAIVGCDCS-DCFKGKC-CPTEAGVLFAYNEHRQIKIPPGRPIYECNSRCKCGPDCPNRVVQKGPPYSLCIFRTDNGRGWGVKTLQKIKKNSFVMEYVGEVITSEEAERRGQQYDSRGITYLFDLDYEAD-EFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDVRLPRIALFSTRNIKAGEELTFDYQM 370
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Xenopus
Match: slc7a2.1 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 2, gene 1 [Source:Xenbase;Acc:XB-GENE-994549])

HSP 1 Score: 160.229 bits (404), Expect = 1.412e-40
Identity = 94/239 (39.33%), Postives = 137/239 (57.32%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHG--GDPP----YTVTGKVIPKFG----VPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            I   Y    +   N VD E  P D++++++   +S  +  D  I      SC+D   DCSS +   G       Y   G+++ +F       I+ECN ACSC   C  RVVQ G+K++L+++RT   GWG++ L  I +G FI EY+GE+++  EA+ R      ++ +YLFDLD      + +DA   GN+S FINH C PN+    VF+++ D+R PRIAFF+ RDI+AGEEL FDY
Sbjct:  835 IAHGYERVPIPCVNGVDEELCPDDYKYVSENCETSA-MSIDRNITHLQNCSCVD---DCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWQTCKNRVVQSGIKVRLQLYRTAKMGWGVRALQAIPQGTFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNVSRFINHLCEPNLIPVRVFMSHQDLRFPRIAFFSGRDIRAGEELGFDY 1063
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Xenopus
Match: slc7a2.1 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 2, gene 1 [Source:Xenbase;Acc:XB-GENE-994549])

HSP 1 Score: 159.844 bits (403), Expect = 1.676e-40
Identity = 94/239 (39.33%), Postives = 137/239 (57.32%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHG--GDPP----YTVTGKVIPKFG----VPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            I   Y    +   N VD E  P D++++++   +S  +  D  I      SC+D   DCSS +   G       Y   G+++ +F       I+ECN ACSC   C  RVVQ G+K++L+++RT   GWG++ L  I +G FI EY+GE+++  EA+ R      ++ +YLFDLD      + +DA   GN+S FINH C PN+    VF+++ D+R PRIAFF+ RDI+AGEEL FDY
Sbjct:  795 IAHGYERVPIPCVNGVDEELCPDDYKYVSENCETSA-MSIDRNITHLQNCSCVD---DCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWQTCKNRVVQSGIKVRLQLYRTAKMGWGVRALQAIPQGTFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNVSRFINHLCEPNLIPVRVFMSHQDLRFPRIAFFSGRDIRAGEELGFDY 1023
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Xenopus
Match: slc7a2.1 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 2, gene 1 [Source:Xenbase;Acc:XB-GENE-994549])

HSP 1 Score: 159.844 bits (403), Expect = 1.724e-40
Identity = 94/239 (39.33%), Postives = 137/239 (57.32%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHG--GDPP----YTVTGKVIPKFG----VPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            I   Y    +   N VD E  P D++++++   +S  +  D  I      SC+D   DCSS +   G       Y   G+++ +F       I+ECN ACSC   C  RVVQ G+K++L+++RT   GWG++ L  I +G FI EY+GE+++  EA+ R      ++ +YLFDLD      + +DA   GN+S FINH C PN+    VF+++ D+R PRIAFF+ RDI+AGEEL FDY
Sbjct:  808 IAHGYERVPIPCVNGVDEELCPDDYKYVSENCETSA-MSIDRNITHLQNCSCVD---DCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWQTCKNRVVQSGIKVRLQLYRTAKMGWGVRALQAIPQGTFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNVSRFINHLCEPNLIPVRVFMSHQDLRFPRIAFFSGRDIRAGEELGFDY 1036
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Mouse
Match: Suv39h2 (suppressor of variegation 3-9 2 [Source:MGI Symbol;Acc:MGI:1890396])

HSP 1 Score: 255.373 bits (651), Expect = 8.763e-78
Identity = 162/428 (37.85%), Postives = 211/428 (49.30%), Query Frame = 1 
Query:  226 YEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETY-PLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNR-GWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSEST--SSLQITGRVPCLCKSEKCRKFL 1494
            YEVE + D       + YLVKWK W     TWEP +NL  C    R++   K                                          T L  +   +  NS    P      +  +  + AL  W+  +N        + VENTVD EGPPLDF +I +Y  +  I I+S+    C CT    D  K C +  G    Y    ++  + G PIYECNS C C   CP R+VQ+G +  L IFRT N  GWG+KTL KI R +F+MEY+GE++  +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD R+PRIA F+ R I AGEELTFDY M G+                         EA S+S   S  +   R  C C +E CR +L
Sbjct:  118 YEVEYLCDYKVAKGVEYYLVKWKGWPDSTNTWEPLRNL-RCPQLLRQFSDDK-----------------------------------------KTYLAQERKCKAVNSKSLQPAIAEYIVQKAKQRIALQRWQDYLNRRKNHKGMIFVENTVDLEGPPLDFYYINEYRPAPGISINSEATFGCSCTDCFFD--KCCPAEAGVVLAYNKKQQIKIQPGTPIYECNSRCRCGPECPNRIVQKGTQYSLCIFRTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESD-EFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGS------------------------GEASSDSIDHSPAKKRVRTQCKCGAETCRGYL 476
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Mouse
Match: Suv39h2 (suppressor of variegation 3-9 2 [Source:MGI Symbol;Acc:MGI:1890396])

HSP 1 Score: 249.21 bits (635), Expect = 1.197e-76
Identity = 157/411 (38.20%), Postives = 204/411 (49.64%), Query Frame = 1 
Query:  277 YLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETY-PLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNR-GWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSEST--SSLQITGRVPCLCKSEKCRKFL 1494
            YLVKWK W     TWEP +NL  C    R++   K                                          T L  +   +  NS    P      +  +  + AL  W+  +N        + VENTVD EGPPLDF +I +Y  +  I I+S+    C CT    D  K C +  G    Y    ++  + G PIYECNS C C   CP R+VQ+G +  L IFRT N  GWG+KTL KI R +F+MEY+GE++  +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD R+PRIA F+ R I AGEELTFDY M G+                         EA S+S   S  +   R  C C +E CR +L
Sbjct:   33 YLVKWKGWPDSTNTWEPLRNL-RCPQLLRQFSDDK-----------------------------------------KTYLAQERKCKAVNSKSLQPAIAEYIVQKAKQRIALQRWQDYLNRRKNHKGMIFVENTVDLEGPPLDFYYINEYRPAPGISINSEATFGCSCTDCFFD--KCCPAEAGVVLAYNKKQQIKIQPGTPIYECNSRCRCGPECPNRIVQKGTQYSLCIFRTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESD-EFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGS------------------------GEASSDSIDHSPAKKRVRTQCKCGAETCRGYL 374
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Mouse
Match: Suv39h1 (suppressor of variegation 3-9 1 [Source:MGI Symbol;Acc:MGI:1099440])

HSP 1 Score: 250.366 bits (638), Expect = 1.271e-76
Identity = 161/430 (37.44%), Postives = 226/430 (52.56%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYP-LFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++EVE + D  +   ++ YLVKW+ +     TWEP++NL  C    +++ K  LE               EL+ +  RS       P H+   L   L  K+ +R+                      AL  WE  +N     L ++TVEN VD +GPP  F +I +Y        +   + C C    +     C   +S+H     Y   G+V  K G PIYECNS C C  +CP RVVQ+G++  L IFRT + RGWG++TL KI + +F+MEY+GEI+  +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R I AGEELTFDY M     D +             ++ N    AG   +   ++  R+ C C +  CRK+L+
Sbjct:   42 DFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNL-KCIRVLKQFHK-DLER--------------ELVRRHRRSKP-----PRHLDPNLANYLVQKAKQRR----------------------ALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLH--KFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYDLCIFRTNDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYNMQVDPVDMESTR----------MDSNFGL-AGLPGSPKKRV--RIECKCGTTACRKYLF 412
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Mouse
Match: Suv39h1 (suppressor of variegation 3-9 1 [Source:MGI Symbol;Acc:MGI:1099440])

HSP 1 Score: 250.366 bits (638), Expect = 1.703e-76
Identity = 161/430 (37.44%), Postives = 226/430 (52.56%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYP-LFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++EVE + D  +   ++ YLVKW+ +     TWEP++NL  C    +++ K  LE               EL+ +  RS       P H+   L   L  K+ +R+                      AL  WE  +N     L ++TVEN VD +GPP  F +I +Y        +   + C C    +     C   +S+H     Y   G+V  K G PIYECNS C C  +CP RVVQ+G++  L IFRT + RGWG++TL KI + +F+MEY+GEI+  +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R I AGEELTFDY M     D +             ++ N    AG   +   ++  R+ C C +  CRK+L+
Sbjct:   43 DFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNL-KCIRVLKQFHK-DLER--------------ELVRRHRRSKP-----PRHLDPNLANYLVQKAKQRR----------------------ALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLH--KFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYDLCIFRTNDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGEELTFDYNMQVDPVDMESTR----------MDSNFGL-AGLPGSPKKRV--RIECKCGTTACRKYLF 413
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Mouse
Match: Ehmt1 (euchromatic histone methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1924933])

HSP 1 Score: 160.614 bits (405), Expect = 9.032e-41
Identity = 92/240 (38.33%), Postives = 141/240 (58.75%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFIT-DYVSSSIEIHSDPPIACYCTTSCIDNKKDCSS--IHGGDPP----YTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            I   Y    +   N VD+E  P ++++++ + V+S + I  +     YC   C+D   DCSS     G       Y   G+++P+F +     I+ECN ACSC  NC  RVVQ G++ +L+++RT++ GWG+++L  I  G F+ EY+GE+++  EA+ R      +  +YLFDLD      + +DA   GN+S FINH C PN+    VF+++ D+R PRIAFF+ R I+AGE+L FDY
Sbjct:  964 IARGYERIPIPCVNAVDSELCPTNYKYVSQNCVTSPMNIDRNITHLQYCV--CVD---DCSSSTCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTQDMGWGVRSLQDIPLGTFVCEYVGELISDSEADVR------EEDSYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMSHQDLRFPRIAFFSTRLIQAGEQLGFDY 1192
[Close]
BLAST of Histone-lysine N-methyltransferase vs. UniProt/SwissProt
Match: sp|Q5RB81|SUV91_PONAB (Histone-lysine N-methyltransferase SUV39H1 OS=Pongo abelii OX=9601 GN=SUV39H1 PE=2 SV=1)

HSP 1 Score: 256.914 bits (655), Expect = 3.056e-78
Identity = 162/430 (37.67%), Postives = 229/430 (53.26%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYP-LFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++EVE + D  +   ++ YLVKW+ +     TWEP++NL  C    +++ K  LE               EL+ +  RS T     P H+   L   L  K+ +R                      +AL  WE  +N     L ++TVEN VD +GPP  F +I +Y        +   + C C          C   +S+H     Y   G+V  + G+PIYECNS C C  +CP RVVQ+G++  L IFRT + RGWG++TL KI + +F+MEY+GEI+  +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R I+AGEELTFDY M     D +             ++ N    AG   +   ++  R+ C C +E CRK+L+
Sbjct:   42 DFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNL-KCVRILKQFHK-DLER--------------ELLRRHHRSKT-----PRHLDPSLANYLVQKAKQR----------------------RALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLH--KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTR----------MDSNFGL-AGLPGSPKKRV--RIECKCGTESCRKYLF 412
[Close]
BLAST of Histone-lysine N-methyltransferase vs. UniProt/SwissProt
Match: sp|O43463|SUV91_HUMAN (Histone-lysine N-methyltransferase SUV39H1 OS=Homo sapiens OX=9606 GN=SUV39H1 PE=1 SV=1)

HSP 1 Score: 256.914 bits (655), Expect = 3.056e-78
Identity = 162/430 (37.67%), Postives = 229/430 (53.26%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYP-LFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++EVE + D  +   ++ YLVKW+ +     TWEP++NL  C    +++ K  LE               EL+ +  RS T     P H+   L   L  K+ +R                      +AL  WE  +N     L ++TVEN VD +GPP  F +I +Y        +   + C C          C   +S+H     Y   G+V  + G+PIYECNS C C  +CP RVVQ+G++  L IFRT + RGWG++TL KI + +F+MEY+GEI+  +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R I+AGEELTFDY M     D +             ++ N    AG   +   ++  R+ C C +E CRK+L+
Sbjct:   42 DFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNL-KCVRILKQFHK-DLER--------------ELLRRHHRSKT-----PRHLDPSLANYLVQKAKQR----------------------RALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLH--KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTR----------MDSNFGL-AGLPGSPKKRV--RIECKCGTESCRKYLF 412
[Close]
BLAST of Histone-lysine N-methyltransferase vs. UniProt/SwissProt
Match: sp|Q2NL30|SUV91_BOVIN (Histone-lysine N-methyltransferase SUV39H1 OS=Bos taurus OX=9913 GN=SUV39H1 PE=2 SV=1)

HSP 1 Score: 254.988 bits (650), Expect = 1.971e-77
Identity = 161/430 (37.44%), Postives = 228/430 (53.02%), Query Frame = 1 
Query:  223 EYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYP-LFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++EVE + D  +   ++ YLVKW+ +     TWEP++NL  C    +++ K  LE               EL+ +  RS       P H+   L   L  K+ +R                      +AL  WE  +N     L ++TVEN VD +GPP  F +I +Y        +   + C C          C   +S+H     Y   G+V  + G+PIYECNS C C  +CP RVVQ+G++  L IFRT + RGWG++TL KI + +F+MEY+GEI+  +EAE RG++YD+Q  TYLFDLD+  D  +TVDA   GN+SHF+NHSC+PN+    VFI+NLD R+PRIAFFA R I+AGEELTFDY M     D +             ++ N    AG   +   ++  R+ C C +E CRK+L+
Sbjct:   42 DFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNL-KCVRILKQFHK-DLER--------------ELLRRHHRSKP-----PRHLDPSLANYLVQKAKQR----------------------RALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPAGGCCPGASLH--KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDV-YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTR----------MDSNFGL-AGLPGSPKKRV--RIECKCGTESCRKYLF 412
[Close]
BLAST of Histone-lysine N-methyltransferase vs. UniProt/SwissProt
Match: sp|Q5F3W5|SUV92_CHICK (Histone-lysine N-methyltransferase SUV39H2 OS=Gallus gallus OX=9031 GN=SUV39H2 PE=2 SV=1)

HSP 1 Score: 254.218 bits (648), Expect = 2.449e-77
Identity = 154/375 (41.07%), Postives = 208/375 (55.47%), Query Frame = 1 
Query:  220 QEYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDW-ETLINETYPLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAI 1335
            + YEVE + D   E+ ++ YLVKWK W     TWEP+KNL  C         + LEN    F+ D  +                         YL  + + ++ K + +     P      +  +  + AL  W E L  +      + VENTVD EGPP+DF +I +Y  +  I + +     C C+      +K C    G    Y    K+  + G+PIYECNS C C  +CP R+VQ+G +  L IFRT N RGWG+KTL KI   +F+MEY+GE++  +EAE RG+ YD Q  TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD+R+PRIA F+ R IKAGEELTFDY M G+I
Sbjct:   41 KSYEVEYLCDYKVEEGKEYYLVKWKGWPESSNTWEPQKNL-KCP--------KLLEN----FLSDKDE-------------------------YLSRMKEGRALKVRNSVKALKPAVADYIVKKAKQRIALQRWKEELNRKKNHKGMILVENTVDLEGPPIDFYYINEYKPAPGINVINGITTGCECSD--CPAEKCCPKEAGFILAYNKQKKLKIQPGLPIYECNSFCRCGPDCPNRIVQKGTQYSLCIFRTNNGRGWGVKTLQKIKTNSFVMEYVGEVITSEEAERRGQFYDNQGNTYLFDLDYDSD-EFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDLRLPRIALFSTRTIKAGEELTFDYQMKGSI 374
[Close]
BLAST of Histone-lysine N-methyltransferase vs. UniProt/SwissProt
Match: sp|Q9EQQ0|SUV92_MOUSE (Histone-lysine N-methyltransferase SUV39H2 OS=Mus musculus OX=10090 GN=Suv39h2 PE=1 SV=1)

HSP 1 Score: 254.218 bits (648), Expect = 2.172e-76
Identity = 161/428 (37.62%), Postives = 211/428 (49.30%), Query Frame = 1 
Query:  226 YEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETY-PLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNR-GWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSEST--SSLQITGRVPCLCKSEKCRKFL 1494
            YEVE + D       + YLVKWK W     TWEP +NL  C    R++   K                                          T L  +   +  NS    P      +  +  + AL  W+  +N        + VENTVD EGPPLDF +I +Y  +  I I+S+    C CT    D  K C +  G    Y    ++  + G PIYECNS C C   CP R+VQ+G +  L IF+T N  GWG+KTL KI R +F+MEY+GE++  +EAE RG+ YD + +TYLFDLD+  D EFTVDA + GN+SHF+NHSC+PN+    VFI+NLD R+PRIA F+ R I AGEELTFDY M G+                         EA S+S   S  +   R  C C +E CR +L
Sbjct:  118 YEVEYLCDYKVAKGVEYYLVKWKGWPDSTNTWEPLRNL-RCPQLLRQFSDDK-----------------------------------------KTYLAQERKCKAVNSKSLQPAIAEYIVQKAKQRIALQRWQDYLNRRKNHKGMIFVENTVDLEGPPLDFYYINEYRPAPGISINSEATFGCSCTDCFFD--KCCPAEAGVVLAYNKKQQIKIQPGTPIYECNSRCRCGPECPNRIVQKGTQYSLCIFKTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESD-EFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGS------------------------GEASSDSIDHSPAKKRVRTQCKCGAETCRGYL 476
[Close]
BLAST of Histone-lysine N-methyltransferase vs. TrEMBL
Match: A0A267DBX9 (Histone-lysine N-methyltransferase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032093g3 PE=3 SV=1)

HSP 1 Score: 321.242 bits (822), Expect = 3.263e-99
Identity = 184/506 (36.36%), Postives = 273/506 (53.95%), Query Frame = 1 
Query:   70 TITDKQVKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEA--EEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYE-----KRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKR-----KKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSS-SIEIHSDPPIACYCTTSCIDNKKDCSSIH---GGDPPYTVTGKVIPKF--GVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQIT------------GRVPCLCKSEKCRKFLY 1497
             +    +K  + N+  +  L    L+S   +  ++ + LI   ++K E D EYEVE+I D    E D    YL+KW+ W IE  TWEP+ +L NC++  +EY+     K +        V + ++     + Q+   I   ++ P    + L   L  ++ +      I LP++ R     K+ +   I+  L +WE L+N   P  K+ +EN VD EGPPL F ++T  V    + I  DP + C CT  C + +  C + H    G  PYT  G+ +P      PI+ECNS C C  +CP+RVVQRG +  L I+RTKNRGWG++TL +I RG+F++EY+GE+V  +EAE RG  YD+Q  TYLFDLD  G+P ++VDA   GN++HF+NHSC+PN+T RCV+   +D  +P +A FAA  I  G ELTFDY M+GAIS                +  +   E+ +E+ S +  +             R+ CLC S  CR+FL+
Sbjct:   21 VLQSNNLKFPNDNVAQFVALHLQKLNSN--QALHVISNLITQELVKYE-DAEYEVESIEDHDWDEVDQTMRYLIKWRGWPIECATWEPEPDLTNCQELLKEYKNFISGKSRKRRPTAAEVAESSERSKARVLQLLDCINFDDLTPERFEQVLAETLTKRALQSVAKRRI-LPSQSRMIAGSKRSLGIKIQAELKNWELLLNANEPRAKIVIENKVDLEGPPLAFTYVTKRVPGPGVSIPDDPVLGCTCT-DCYEERHSCVASHVHNEGRVPYTRQGR-LPNVHASFPIHECNSLCKCGPDCPFRVVQRGRQFGLAIYRTKNRGWGVRTLQRIPRGSFVVEYVGEVVTFEEAERRGLEYDRQAQTYLFDLDLDGEPVYSVDARDYGNIAHFLNHSCSPNLTIRCVYTQCIDKDLPLLALFAAEPIPKGAELTFDYQMSGAIS------AEQQQQQQQQLGADDASESAAENASVVSSSVGGASSVNGGGLARMRCLCGSANCRRFLF 514
[Close]
BLAST of Histone-lysine N-methyltransferase vs. TrEMBL
Match: A0A1I8J5Y4 (Histone-lysine N-methyltransferase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027750g1 PE=3 SV=1)

HSP 1 Score: 320.087 bits (819), Expect = 8.209e-99
Identity = 185/506 (36.56%), Postives = 274/506 (54.15%), Query Frame = 1 
Query:   70 TITDKQVKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEA--EEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYE-----KRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKR-----KKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSS-SIEIHSDPPIACYCTTSCIDNKKDCSSIH---GGDPPYTVTGKVIPKFGV--PIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSES--------TSSLQITG----RVPCLCKSEKCRKFLY 1497
             +    +K  + N+  +  L    L+S   +  ++ + LI   ++K E D EYEVE+I D    E D    YL+KW+ W IE  TWEP+ +L NC++  +EY+     K +        V + ++     + Q+   I   ++ P    + L   L  ++ +      I LP++ R     K+ +   I+  L +WE L+N   P  K+ +EN VD EGPPL F ++T  V    + I  DP + C CT  C + +  C + H    G  PYT  G+ +P      PI+ECNS C C  +CP+RVVQRG +  L I+RTKNRGWG++TL +I RG+F++EY+GE+V  +EAE RG  YD+Q  TYLFDLD  G+P ++VDA   GN++HF+NHSC+PN+T RCV+   +D  +P +A FAA  I  G ELTFDY M+GAIS       +        +  +   E+ +E+          +  I G    R+ CLC S  CR+FL+
Sbjct:   21 VLQSNNLKFPNDNVVQFVALHLQKLNSN--QALHVISNLITQELVKYE-DAEYEVESIEDHDWDEVDQTMRYLIKWRGWPIECATWEPEPDLTNCQELLKEYKNFISGKSRKRRPTAAEVAESSERSKARVLQLLDCINFDDLTPERFEQVLAETLTKRALQSVAKRRI-LPSQSRMIAGSKRSLAIKIQAELKNWELLLNANEPQAKIFIENKVDLEGPPLAFTYVTKRVPGPGVSIPDDPVLGCTCT-DCYEERHSCVASHVHNEGRVPYTRQGR-LPNVNASFPIHECNSLCKCGPDCPFRVVQRGRQFGLAIYRTKNRGWGVRTLQRIPRGSFVVEYVGEVVTFEEAERRGLEYDRQAQTYLFDLDLDGEPVYSVDARDYGNIAHFLNHSCSPNLTIRCVYTQCIDKDLPLLALFAAEPIPKGAELTFDYQMSGAIS-------AEQQQQQQQLGADDASESAAENASVVSSSVGGASSINGGGLARMRCLCGSANCRRFLF 513
[Close]
BLAST of Histone-lysine N-methyltransferase vs. TrEMBL
Match: A0A1I8GFF2 (Histone-lysine N-methyltransferase OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 314.694 bits (805), Expect = 2.185e-97
Identity = 172/435 (39.54%), Postives = 250/435 (57.47%), Query Frame = 1 
Query:   88 VKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEA--EEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYE-----KRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKR-----KKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSS-SIEIHSDPPIACYCTTSCIDNKKDCSSIH---GGDPPYTVTGKVIPKF--GVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAIS 1338
            +K  + N+  +  L    L+S   +  ++ + LI   ++K E D EYEVE+I D    E D    YL+KW+ W IE  TWEP+ +L NC++  +EY+     K +        V + ++     + Q+   I   ++ P    + L   L  ++ +      I LP++ R     K+ +   I+  L +WE L+N   P  K+ +EN VD EGPPL F ++T  V    + I  DP + C CT  C + +  C + H    G  PYT  G+ +P      PI+ECNS C C  +CP+RVVQRG +  L I+RTKNRGWG++TL +I RG+F++EY+GE+V  +EAE RG  YD+Q  TYLFDLD  G+P ++VDA   GN++HF+NHSC+PN+T RCV+   +D  +P +A FAA  I  G ELTFDY M+GAIS
Sbjct:   27 LKFPNDNVAQFVALHLQKLNSN--QALHVISNLITQELVKYE-DAEYEVESIEDHDWDEVDQTMRYLIKWRGWPIECATWEPEPDLTNCQELLKEYKNFISGKSRKRRPTAAEVAESSERSKARVLQLLDCINFDDLTPERFEQVLAETLTKRALQSVAKRRI-LPSQSRMIAGSKRSLGIKIQAELKNWELLLNANEPRAKIVIENKVDLEGPPLAFTYVTKRVPGPGVSIPDDPVLGCTCT-DCYEERHSCVASHVHNEGRVPYTRQGR-LPNVHASFPIHECNSLCKCGPDCPFRVVQRGRQFGLAIYRTKNRGWGVRTLQRIPRGSFVVEYVGEVVTFEEAERRGLEYDRQAQTYLFDLDLDGEPVYSVDARDYGNIAHFLNHSCSPNLTIRCVYTQCIDKDLPLLALFAAEPIPKGAELTFDYQMSGAIS 455
[Close]
BLAST of Histone-lysine N-methyltransferase vs. TrEMBL
Match: A0A1I8I7P4 (Histone-lysine N-methyltransferase OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 314.694 bits (805), Expect = 2.251e-97
Identity = 172/435 (39.54%), Postives = 250/435 (57.47%), Query Frame = 1 
Query:   88 VKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEA--EEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYE-----KRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKR-----KKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSS-SIEIHSDPPIACYCTTSCIDNKKDCSSIH---GGDPPYTVTGKVIPKF--GVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAIS 1338
            +K  + N+  +  L    L+S   +  ++ + LI   ++K E D EYEVE+I D    E D    YL+KW+ W IE  TWEP+ +L NC++  +EY+     K +        V + ++     + Q+   I   ++ P    + L   L  ++ +      I LP++ R     K+ +   I+  L +WE L+N   P  K+ +EN VD EGPPL F ++T  V    + I  DP + C CT  C + +  C + H    G  PYT  G+ +P      PI+ECNS C C  +CP+RVVQRG +  L I+RTKNRGWG++TL +I RG+F++EY+GE+V  +EAE RG  YD+Q  TYLFDLD  G+P ++VDA   GN++HF+NHSC+PN+T RCV+   +D  +P +A FAA  I  G ELTFDY M+GAIS
Sbjct:   27 LKFPNDNVAQFVALHLQKLNSN--QALHVISNLITQELVKYE-DAEYEVESIEDHDWDEVDQTMRYLIKWRGWPIECATWEPEPDLTNCQELLKEYKNFISGKSRKRRPTAAEVAESSERSKARVLQLLDCINFDDLTPERFEQVLAETLTKRALQSVAKRRI-LPSQSRMIAGSKRSLGIKIQAELKNWELLLNANEPRAKIVIENKVDLEGPPLAFTYVTKRVPGPGVSIPDDPVLGCTCT-DCYEERHSCVASHVHNEGRVPYTRQGR-LPNVHASFPIHECNSLCKCGPDCPFRVVQRGRQFGLAIYRTKNRGWGVRTLQRIPRGSFVVEYVGEVVTFEEAERRGLEYDRQAQTYLFDLDLDGEPVYSVDARDYGNIAHFLNHSCSPNLTIRCVYTQCIDKDLPLLALFAAEPIPKGAELTFDYQMSGAIS 455
[Close]
BLAST of Histone-lysine N-methyltransferase vs. TrEMBL
Match: A0A0X3P079 (Histone-lysine N-methyltransferase OS=Schistocephalus solidus OX=70667 GN=TR117325 PE=3 SV=1)

HSP 1 Score: 315.079 bits (806), Expect = 3.963e-96
Identity = 191/542 (35.24%), Postives = 291/542 (53.69%), Query Frame = 1 
Query:   82 KQVKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDIS-----------LPNKKRKKIV---LSTIKKALSDWETLINETY----PLFKVTVENTVDTEGPPLDFQFITDYVSSS-IEIHSDPPIACYCT-----TSC-------------IDNKKDCSSIHGGDP-PYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINV------------------NTKYEAGS----ESTSSLQITGRVP----------CLCKSEKCRKFL 1494
            K +KLSD    ++ LLE L      + +  + N L +++V+    D EY VEAIL ++    +  Y VKW+ W   F TWEP++NL  CE    E+   K         +   +   E+++++  ++    + P+ +          + +K ++   +S              +KRK+     L+ +K++LS +E ++N  Y    PL    VEN VD E PP+DFQ I DYV    + + +   + C C       SC             I+    C ++  G   PY++  +++   G  I+ECNSAC+C  +CP+RVVQ G K+ L IFRTKN RGWG+KTL +I +G F+MEYLGEI+  + AE+RG+LYD+Q +TYLFDLDF G+  +TVDA + GN+SHF+NHSC+PN+T RC FI  ++I++PR+A FAAR+I  GEELTFDY MTGA   ++ +E + V   ++S ++                  +   E GS    E+ S +  + + P          CLC ++KCR +L
Sbjct:   30 KDIKLSDEA--AFGLLESLLTRFPLRVVYKVLNTLCQNDVLTFSSDSEYVVEAILKKSNIMGKNYYFVKWEGWPPTFNTWEPEENLAGCEKLINEFLSHKSPYPAVKEPVGKQKQLSEVLDRLKEAVPLSRISPTELLSLFLEHFPPEESKLRRFYQLSNHCVSYVEGAHPKARKRKRPTAESLTALKESLSAFEAMLNSVYCKEAPL---RVENNVDLECPPIDFQPICDYVPDEDVHLPTKAVVGCECAPLEAVQSCDKSLRSAELEPCWINRHNSCCAVRSGARIPYSINKRLLVPPGHAIFECNSACACGPSCPFRVVQLGRKVPLSIFRTKNGRGWGVKTLQRIPKGTFVMEYLGEIITFEGAEKRGQLYDKQRMTYLFDLDFDGEAHYTVDALQMGNVSHFVNHSCDPNLTVRCAFIECMNIKLPRLALFAARNICKGEELTFDYQMTGARDGDEGDEANFVCDGSTSCDLPDDCSESNSLSNNSRCQPSNPSENGSVCTPENCSDVSSSSKTPSVTSKSLKMKCLCGAKKCRGYL 566
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Cavefish
Match: suv39h1b (suppressor of variegation 3-9 homolog 1b [Source:ZFIN;Acc:ZDB-GENE-030131-5105])

HSP 1 Score: 249.98 bits (637), Expect = 5.779e-77
Identity = 144/360 (40.00%), Postives = 204/360 (56.67%), Query Frame = 1 
Query:  259 EDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETY-PLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKD--CSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMM 1323
            E+ +++YLVKWK +     +WEP+KNL  C D   ++ +                   +++ ++ R      +K   + K L   L S   +R K                  ++K L  WET +N       ++ VEN VD EGPP +F +I DY V   I + ++  + C CT  C+++  +  C+        Y   G+V  + G+P+YECN  C C   CP RVVQ+G++  L IFRT N RGWG++T+ +I +  F+MEY+GEI+  +EAE RG +YD++  TYLFDLD+  D E+TVDA   GN+SHF+NHSC+PN+    VFI NLD R+PRIAFFA R IKAGEELTFDY M
Sbjct:   62 EEVQELYLVKWKGYPESMNSWEPRKNL-KCTDLLSQFWE-------------------DMVRELRR------LKKRTIPKKLDASLASHLVQRAK------------------LRKTLKQWETHLNSLGNKKGRIFVENLVDMEGPPKNFTYINDYKVGDGISL-TEVAVGCECT-DCLNDPVEGCCAGASQHKFAYNELGQVRVRPGLPVYECNRRCRCGPECPNRVVQKGIQYSLCIFRTDNGRGWGVRTMERIRKNTFVMEYVGEIITTEEAERRGHVYDKEGTTYLFDLDYV-DDEYTVDAAHYGNISHFVNHSCDPNLQVYNVFIENLDERLPRIAFFATRPIKAGEELTFDYKM 374
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Cavefish
Match: suv39h1b (suppressor of variegation 3-9 homolog 1b [Source:ZFIN;Acc:ZDB-GENE-030131-5105])

HSP 1 Score: 250.751 bits (639), Expect = 6.698e-77
Identity = 153/414 (36.96%), Postives = 221/414 (53.38%), Query Frame = 1 
Query:  271 KVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETY-PLFKVTVENTVDTEGPPLDFQFITDY-VSSSIEIHSDPPIACYCTTSCIDNKKD--CSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            ++YLVKWK +     +WEP+KNL  C D   ++ +                   +++ ++ R      +K   + K L   L S   +R K                  ++K L  WET +N       ++ VEN VD EGPP +F +I DY V   I + ++  + C CT  C+++  +  C+        Y   G+V  + G+P+YECN  C C   CP RVVQ+G++  L IFRT N RGWG++T+ +I +  F+MEY+GEI+  +EAE RG +YD++  TYLFDLD+  D E+TVDA   GN+SHF+NHSC+PN+    VFI NLD R+PRIAFFA R IKAGEELTFDY M     D +               +++ +   +E   S +   R+ C C    CRK+L+
Sbjct:   55 ELYLVKWKGYPESMNSWEPRKNL-KCTDLLSQFWE-------------------DMVRELRR------LKKRTIPKKLDASLASHLVQRAK------------------LRKTLKQWETHLNSLGNKKGRIFVENLVDMEGPPKNFTYINDYKVGDGISL-TEVAVGCECT-DCLNDPVEGCCAGASQHKFAYNELGQVRVRPGLPVYECNRRCRCGPECPNRVVQKGIQYSLCIFRTDNGRGWGVRTMERIRKNTFVMEYVGEIITTEEAERRGHVYDKEGTTYLFDLDYV-DDEYTVDAAHYGNISHFVNHSCDPNLQVYNVFIENLDERLPRIAFFATRPIKAGEELTFDYKMQMDPVDAESTR------------MDSNF-GLTEIPGSPKKRMRIECKCGVASCRKYLF 408
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Cavefish
Match: suv39h1a (histone-lysine N-methyltransferase SUV39H1-A [Source:NCBI gene;Acc:103040252])

HSP 1 Score: 236.884 bits (603), Expect = 1.329e-71
Identity = 133/299 (44.48%), Postives = 181/299 (60.54%), Query Frame = 1 
Query:  610 LSDWETLINETYPL-FKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDP-PYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            L  WE  +N T     ++ V N VD +GPP DF +I+DY            + C CT    D+ K C +        Y  + +V  + G+PIYECNS CSC  +C  RVVQRG++  L IF+T N RGWG++TL +I + +F+MEYLGEI+  +EAE RG+ YD+Q +TYLFDLD+  D  +TVDA + GN+SHF+NHSC+PN+    VFI + D R+PRIAFFA R IKAGEELTFDY MT    D +  +          ++ N    AG + T   ++  R+ C C +E CRK+L+
Sbjct:  127 LLRWEEQLNRTCKHKGRIFVLNEVDMDGPPTDFMYISDYKIEKGVKARQAAVGCKCTNCIKDSIKGCCAGAADHRIAYNDSRQVKVRPGLPIYECNSRCSCGPDCGNRVVQRGIQYDLCIFKTANGRGWGVRTLERINKNSFVMEYLGEIITSEEAERRGEKYDKQGVTYLFDLDYVDDV-YTVDAARCGNISHFVNHSCDPNLQVYNVFIEHSDERLPRIAFFATRAIKAGEELTFDYKMTIDELDAESTK----------MDANFSL-AGIQDTPIKRM--RMECKCGAENCRKYLF 411
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Cavefish
Match: ehmt2 (euchromatic histone-lysine N-methyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-010501-6])

HSP 1 Score: 154.066 bits (388), Expect = 1.479e-41
Identity = 92/259 (35.52%), Postives = 147/259 (56.76%), Query Frame = 1 
Query:  565 NKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIA----CYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFG----VPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            N+K ++ + + I +      + + + Y    +   N VD EG P D+++I +   +S  ++ D  I     C CT  C  +   C  +      Y    +++ +F       I+ECN ACSC  +C  RVVQ G+K++L+++RT+  GWG++ L  I +G+FI EY+GE+++  EA+ R      ++ +YLFDLD      + +DA   GN+S FINH C+PN+    VF+ + D+R PRIAFF++RDI  G+EL FDY
Sbjct:   25 NRKLRRGIANRIIRTERIICSDVAQGYENVPIPCVNGVDDEGCPSDYKYIAENCETS-AMNIDRNITHLQHCSCTDDCSSSNCLCGQL-SIRCWYDKDQRLLQEFNKIEPPLIFECNLACSCYKSCKNRVVQAGMKVRLQLYRTEKMGWGVRALQDIPQGSFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDILTGQELGFDY 275
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Cavefish
Match: ehmt1b (euchromatic histone lysine methyltransferase 1 [Source:NCBI gene;Acc:103025689])

HSP 1 Score: 155.221 bits (391), Expect = 3.418e-39
Identity = 91/237 (38.40%), Postives = 135/237 (56.96%), Query Frame = 1 
Query:  631 INETYPLFKVTVENTVDTEGPPLDFQFITD-YVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPP---YTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            I   Y    V   N VD+E  P D++++ D  V+S + I  +     YC   C D+    S + G       Y    +++P+F       I+ECN ACSC   C  RVVQ G++++L++FRT+ +GWG++TL  I +G F+ EY+GEI++  EA+ R      +N +YLF LD      + +DA   GN+S FINH C PN+    VF ++ D+R P IAFFA++ I +G+EL FDY
Sbjct: 1011 IARGYERVPVPCVNIVDSEPCPDDYKYVPDNCVTSPMNIDKNITHLQYCV--CKDDCSSASCMCGQLSLRCWYDQESRLLPEFCCEEPPLIFECNHACSCWRTCKNRVVQNGLRIRLQLFRTQKKGWGVRTLQDIPQGTFVCEYVGEIISDAEADVR------ENDSYLFSLDSKVGDMYCIDARFYGNISRFINHHCEPNLFPCRVFTSHQDLRFPHIAFFASKSISSGDELGFDY 1239
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Sea Lamprey
Match: SUV39H2 (suppressor of variegation 3-9 homolog 2 [Source:HGNC Symbol;Acc:HGNC:17287])

HSP 1 Score: 244.202 bits (622), Expect = 5.683e-75
Identity = 157/432 (36.34%), Postives = 227/432 (52.55%), Query Frame = 1 
Query:  226 YEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPS-HVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALS---DWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVS-SSIEIHSDPPIACYCTTSCIDNKKD--CSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            YEVE + +  ++++ + YLVKWK +     +W  +K+L  C+D    + K      K        Q +++++N           KP  H+ K  PT+ +             L  K +++++L+  +K L+   +   LI          VEN VD EGPP  F +I +Y     + +  +P + C C   C   + +  C +I+     Y  +G+V  K G PIYECNS C C   C  RVVQ+G+   L IFRT N RGWG+KT+ KI + +F+MEY+GE++  +EAE RG +YD+   TYLFDLDF  D ++TVDA   GN+SHF+NHSC PN+     FINN D   PRIAFFA  D+ AGEELTFDY +  + S N+              + N      +  T+S +   R+ C C +  CRKFLY
Sbjct:   44 YEVEYLCNYQKKEDMEFYLVKWKGYPESENSWLSRKDL-KCKDLLNVFHKDMERESK-------RQRQVQIVN---------GKKPRRHIRKLHPTVAEY------------LKLKGQQRLLLAAWQKDLNRKKNHSALI---------LVENDVDLEGPPASFIYINEYRPMDGVVMAKEPVVGCSCK-DCFSERGNGCCPTINFTSFAYNNSGRVKVKPGTPIYECNSLCQCGPECKNRVVQKGIPFPLCIFRTDNGRGWGVKTMQKIKKNSFVMEYVGELIPSEEAERRGVIYDRAGTTYLFDLDFCKD-DYTVDATFYGNISHFVNHSCEPNLQVYSTFINNHDFSQPRIAFFAMDDLAAGEELTFDYNIKDSSSQNE--------------SCNKDTVLHTTVTTSPKQRARITCKCGASTCRKFLY 421
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Sea Lamprey
Match: setmar (SET domain and mariner transposase fusion gene [Source:ZFIN;Acc:ZDB-GENE-080204-61])

HSP 1 Score: 130.183 bits (326), Expect = 5.311e-34
Identity = 88/288 (30.56%), Postives = 131/288 (45.49%), Query Frame = 1 
Query:  706 QFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSI------HGGDPP--YTVTGKVI--PKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVA----VDEAEERGKLYDQQNLTYLFDL-DFAGDPEFT-------VDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMM---TGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFL 1494
            Q+  DYV        DP         C D + D S +       GGD    Y   G+++    F  PI+ECN  C C   CP RVVQ+G+ ++L++FRT  +GW ++TL  + RG F+ EY+GE++        A  +    D + + YL  + + AGD           VD  + GN+  F+NHSC PN+    V ++++   +PR+A FAARDI  GEEL +DY     + A+  + + +G                              R PC C +  CR  L
Sbjct:   33 QYTPDYVRGP-GCAVDPGELTLPGCECADGRCDASPVACPCLRGGGDGAACYDPAGRLVGDAGFARPIFECNPLCRCGDACPSRVVQKGLAVRLQVFRTARKGWAVRTLEPLGRGRFVCEYVGEVLGGAEARRRAARQASGSDGRAINYLIAVREHAGDGRGVAPATSTYVDPERVGNVGRFLNHSCEPNLVMALVRVHSV---LPRLALFAARDIADGEELCYDYSGREDSSAVCASPDGDGVAGQ--------------------------RKPCFCGAPSCRGVL 290
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004922.1 (pep scaffold:Pmarinus_7.0:GL479351:23010:32607:-1 gene:ENSPMAG00000004401.1 transcript:ENSPMAT00000004922.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 108.612 bits (270), Expect = 6.741e-25
Identity = 90/298 (30.20%), Postives = 136/298 (45.64%), Query Frame = 1 
Query:  454 RSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTV-DTEGPPLDFQ-FITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCD---LNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGA 1332
            R + E  VK S V   +PT   + +  RKK        K++ ++  +  +K     ++  N  Y          V D+  P ++ Q F   +   S E  +  P  C C   C  N K C       P Y    +  P        C +A   D   ++C    +QRG+K  L +  +   GWG+     + +  FI EY GEI++ DEA+ RGK+YD+   ++LF+L    + +F VDA +KGN   F NHS +PN  ++ + +N       RI  FA R I+ GEEL FDY  + A
Sbjct:  501 RQVYEFAVKESSVMPRVPTD-DANTPPRKK--------KRKHRLWAAHCRKIQLKKDSSSNHVYNYQPCDHPGQVCDSSCPCVNAQNFCEKFCQCSSECQNRFP-GCRCKAQC--NTKQC-------PCYLAVRECDPDL---CQTCGAADHWDNRNVSCKNCCIQRGLKKHLLLAPSDVAGWGIFIKVPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNL----NNDFVVDATRKGNKIRFANHSVSPNCYAKVMMVNGDH----RIGIFAKRAIQTGEELFFDYRYSQA 768
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Sea Lamprey
Match: nsd2 (nuclear receptor binding SET domain protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2581])

HSP 1 Score: 95.5153 bits (236), Expect = 1.299e-20
Identity = 54/149 (36.24%), Postives = 78/149 (52.35%), Query Frame = 1 
Query:  880 YECN-SACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMM 1323
            YEC+ S C     C  +   +      +I +T  RGWGL TL  I +G F+ EY+GE++  +E  +R K   ++NL+  + L    D    +DA  KGN S F+NHSC PN  ++   +N       R+  FA  DI  G ELTF+Y +
Sbjct:  993 YECHPSICPAGDRCQNQAFTKRAYPPSQIVKTAGRGWGLLTLVSIRKGEFVNEYVGELIDEEECRKRIKYAHEKNLSNFYMLTIEKD--RIIDAGPKGNFSRFMNHSCQPNCETQKWTVNGDT----RVGLFATSDIATGTELTFNYNL 1135
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005461.1 (pep scaffold:Pmarinus_7.0:GL477205:1717:42601:-1 gene:ENSPMAG00000004962.1 transcript:ENSPMAT00000005461.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 89.3521 bits (220), Expect = 1.089e-18
Identity = 57/155 (36.77%), Postives = 78/155 (50.32%), Query Frame = 1 
Query:  883 EC-NSACSCDLNCPYRVVQRGVK-LQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVA---VDEAEERGKLYDQ---QNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPN--MTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            EC  S+C C   C  R  QR  +   L+ FRT +RGWG++T       + I+EYLGE+++         R ++  Q   Q   Y   LD        +D+Y+ GN + FINHSC PN  M   CV +N +     RI  FA +DI    ELT+DY
Sbjct: 1142 ECVQSSCPCGELCTNRRFQRQERSAGLERFRTTDRGWGVRTTHHFQANDLIIEYLGEVLSEANFRAFAPRSRMLAQRGEQAGMYCVQLDSG----VVIDSYRMGNEARFINHSCQPNCEMQKWCVSVNGIY----RIGLFALKDIPISTELTYDY 1288
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Yeast
Match: SET2 (Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003704])

HSP 1 Score: 83.9593 bits (206), Expect = 2.269e-17
Identity = 52/152 (34.21%), Postives = 84/152 (55.26%), Query Frame = 1 
Query:  871 VPIYEC-NSACS-CDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMP-RIAFFAARDIKAGEELTFDY 1317
            + + EC N  CS C  +C  +  Q+     + IF+TK++G+G++    I    FI EY GE++   E  +R   YDQ++  + + +    + EF +DA  KG+++ F NHSC+PN      ++N   ++   R+  FA R I  GEE+TFDY
Sbjct:   92 LTLIECVNDLCSSCGNDCQNQRFQKKQYAPIAIFKTKHKGYGVRAEQDIEANQFIYEYKGEVIEEMEFRDRLIDYDQRHFKHFYFM-MLQNGEF-IDATIKGSLARFCNHSCSPN-----AYVNKWVVKDKLRMGIFAQRKILKGEEITFDY 236
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Yeast
Match: SET1 (Histone methyltransferase, subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3K4; Set1p-dependent H3K4 trimethylation recruits Nrd1p, allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway; modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination; required in transcriptional silencing near telomeres and at silent mating type loci; has a SET domain [Source:SGD;Acc:S000001161])

HSP 1 Score: 82.8037 bits (203), Expect = 7.117e-17
Identity = 55/178 (30.90%), Postives = 77/178 (43.26%), Query Frame = 1 
Query:  967 RTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNL--TYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFL 1494
            R+    WGL  L  I     I+EY+GE +    AE R K Y +  +  +YLF +D        +DA KKG ++ FINH C+PN T++ + +        RI  +A RDI A EELT+DY       D +                                  R+PCLC +  C+ FL
Sbjct:  944 RSAIHNWGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRYLKNGIGSSYLFRVD----ENTVIDATKKGGIARFINHCCDPNCTAKIIKVGG----RRRIVIYALRDIAASEELTYDYKFEREKDDEE----------------------------------RLPCLCGAPNCKGFL 1079
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Nematostella
Match: EDO36231 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ88])

HSP 1 Score: 213.772 bits (543), Expect = 2.127e-65
Identity = 117/249 (46.99%), Postives = 155/249 (62.25%), Query Frame = 1 
Query:  610 LSDWE-----TLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIH---SDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNR-GWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFA-GDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMT 1326
            L +WE       +NE Y    ++VEN VD   PP DF +I+     S   H    +  + C C   C     +C    GG   Y   G+V  + G PIYECNS CSC  +C  RVVQRG  +++ IFRT N  GWG+KT+  I++  F+ EY+GE++  +EAE RG+ YD    TYLFDLD+  GD  +T+DA K GN+SHFINHSC+PN++   V+++ LD +MPRIAFFA RDI AGEE+TFDY+MT
Sbjct:    2 LEEWEKWLNDCAVNEPY----ISVENKVDNTPPPTDFVYISQNKVPSFLDHLFDHNYLVGCNCQ-RCTPKSCECPKNSGGVFAYDRFGRVQFEPGKPIYECNSKCSCSESCRNRVVQRGRTVRVTIFRTYNGCGWGVKTMDPIMKNQFVTEYVGEVITNEEAEHRGRHYDAAGQTYLFDLDYNDGDCAYTIDAKKYGNISHFINHSCDPNLSVFGVWVDTLDPQMPRIAFFARRDIPAGEEITFDYLMT 245
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Nematostella
Match: EDO35277 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM02])

HSP 1 Score: 139.043 bits (349), Expect = 3.023e-38
Identity = 71/168 (42.26%), Postives = 104/168 (61.90%), Query Frame = 1 
Query:  877 IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLD----------FAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMM-TGAISDNK 1347
            IYECNS C+C   C  RVVQ G++L+L++F+TK+RGWGL+TL  +  G FI  Y G+I+  + A + G+ Y  +   YL +LD          F  +  + +DA   GN   ++NHSC+PN+  + VFI+  D+R P +AFFA  +I AG ELT+DYM   G++ D +
Sbjct:    1 IYECNSNCACSSQCFNRVVQNGIQLRLQVFKTKSRGWGLRTLDDVPCGTFICTYSGQIMNEEMANKEGRDYGDE---YLAELDHIERPTTRSLFGEEHCYVIDAKAYGNCGRYLNHSCSPNLFVQNVFIDTHDLRFPWVAFFAQHNIPAGSELTWDYMYEVGSVQDKE 165
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Nematostella
Match: EDO49808 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFZ3])

HSP 1 Score: 117.857 bits (294), Expect = 5.674e-30
Identity = 61/151 (40.40%), Postives = 96/151 (63.58%), Query Frame = 1 
Query:  874 PIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEER---GKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            PI+ECNS C+CDL+C  ++VQ+ ++ +L++F++K++ WGL+TL  I +G FI EY GE+++  EA++R   GK      +T    +         VD    GN   FINHSC+PN+    V +++L   +P++A FA++DI   EEL+FDY
Sbjct:   63 PIFECNSQCNCDLSCYTKLVQKLIQTRLEVFKSKHKLWGLRTLEHISQGQFICEYAGEVLSYKEAKKRTIEGKGRPNYIITVKEHISGGKILRTHVDPRIYGNAGRFINHSCDPNLVMVPVRVDSL---IPKLALFASKDIFPNEELSFDY 210
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Nematostella
Match: EDO43763 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXE9])

HSP 1 Score: 120.168 bits (300), Expect = 8.112e-30
Identity = 59/149 (39.60%), Postives = 89/149 (59.73%), Query Frame = 1 
Query:  877 IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMM 1323
            + ECN  C C   C  R  Q G K+++++F+T+ +GWG+KTL  + +  F++EY GE++   + + R + YD+Q   + + +    D    +DA  KG++S FINHSC PN  ++   +N L     RI FF  R IKAGEELTFDY +
Sbjct:   53 MIECNHRCPCGDLCTNRRFQEGCKIKVEVFKTEKKGWGVKTLEDLEQNQFVIEYCGEVMNYRDFQSRAQRYDRQKRRHYYFMTLRADE--IIDATLKGSISRFINHSCEPNCVTQKWTVNGL----LRIGFFTLRTIKAGEELTFDYQL 195
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Nematostella
Match: EDO30322 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T142])

HSP 1 Score: 103.605 bits (257), Expect = 4.223e-23
Identity = 53/138 (38.41%), Postives = 80/138 (57.97%), Query Frame = 1 
Query:  916 CPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTG 1329
            C    +QRG +  + +  +   GWG+     + +  FI EY GE+++ DEA+ RGK+YD+   ++LF+L    + +F VDA +KGN   F NHS +PN  ++ + +N       RI  FA RDI+AGEEL FDY  + 
Sbjct:  541 CKNVSLQRGQRKHMLLAPSDVAGWGIYIKQSVKKNEFISEYCGEVISQDEADRRGKVYDKYMCSFLFNL----NNDFVVDATRKGNKIRFANHSISPNCYAKVMMVNGDH----RIGIFAKRDIEAGEELFFDYRYSA 670
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Medaka
Match: suv39h1b (suppressor of variegation 3-9 homolog 1 [Source:NCBI gene;Acc:101155408])

HSP 1 Score: 255.758 bits (652), Expect = 9.425e-79
Identity = 167/438 (38.13%), Postives = 237/438 (54.11%), Query Frame = 1 
Query:  223 EYEVEAILD-EAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKA-----LSDWETLINET--YPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDC---SSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKN-RGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYE-AGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            EYEVE + + +  ++ E+ YLVKWK +     TWEPK+NL  C                            +LI Q                 +L   L  KS KR+     ++P K  K++ L  I+KA     L  W+  +N+T  +P  ++ V N VD EGPP +F +I +Y      + ++  + C C     D    C   +S+H     Y   G+V  + G PIYECNS CSC  +CP RVVQ+G++  L IF+T++ RGWG++TL  I +  F+MEY+GEI+  DEAE+RG LYD+Q  TYLFDLD+  D  +TVDA  +GN+SHF+NHSCNPN+    VFI+N+D R+PRIA F+ R I+AGEELTFDY M     D +  +            +++ +  AG   +   ++  RV C C SE CRK+L+
Sbjct:   42 EYEVEFLCNYKKTKEEEEFYLVKWKGFPESDNTWEPKRNL-KCS---------------------------KLIKQF----------------HLDLDLVLKSQKRR-----AIPKKLDKEVALFLIQKAKLRQSLQRWQDHLNDTRNHP-GRIFVTNDVDLEGPPKNFTYINNYKVGPGIVLNEMAVGCDCKNCLEDPVNGCCPGASLH--RMAYNDRGQVRIRPGKPIYECNSRCSCGPDCPNRVVQKGIQFDLCIFKTEDGRGWGVRTLQGIKKNTFVMEYVGEIITTDEAEKRGHLYDRQGSTYLFDLDYVEDV-YTVDAAHQGNISHFVNHSCNPNLQVFNVFIDNIDERLPRIALFSTRSIRAGEELTFDYKMQIDPVDTESTK------------MDSSFSLAGLPGSPKKRV--RVECRCGSELCRKYLF 412
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Medaka
Match: setmar (histone-lysine N-methyltransferase SETMAR [Source:NCBI gene;Acc:101172575])

HSP 1 Score: 149.443 bits (376), Expect = 3.019e-40
Identity = 89/257 (34.63%), Postives = 134/257 (52.14%), Query Frame = 1 
Query:  754 PPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVI------PKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFD-LDFAGDPEFT---VDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFL 1494
            P  +C   + C    + CS +  G   Y  TG ++        +  P++ECN+ CSC  +C  RVVQ+G++L L++F T N+GWG++TL +I RG F+ EY GE+V+  EA  R      +   Y+   ++ AG    T   VD  + GN+  F+NHSC PN+    V ++++   +P +A FAARD++  EELTFDY  +G     +  E              T+  A +E+ S      R PC C +EKC  FL
Sbjct:   52 PGCSCLSRSCC---PESCSCLQTGGQAYHATGALLDLNRTGSDYSSPVFECNALCSCSDSCSNRVVQKGLQLSLEVFHTSNKGWGVRTLQQIPRGTFVCEYAGEVVSFVEARGRQLSQSAEENNYIIAVVEHAGSGSVTETFVDPTRVGNVGRFLNHSCQPNLVMVPVRVHSV---VPSLALFAARDVRTEEELTFDY--SGGCRKQQPAE-----------TTTTQSPAVAEA-SRPNGQQRKPCRCGAEKCTGFL 288
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Medaka
Match: ehmt1b (histone-lysine N-methyltransferase EHMT1 [Source:NCBI gene;Acc:101167635])

HSP 1 Score: 156.377 bits (394), Expect = 1.546e-39
Identity = 102/289 (35.29%), Postives = 156/289 (53.98%), Query Frame = 1 
Query:  484 SHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITD-YVSSSIEIHSDPPIACYCTTSCIDNKKDCSS--IHGGDPP----YTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            SH  K    L   +  +  +NS +   N+  +K++   +        +L  E  P+  V   N+VD E  P D+++I++  V+S + I  +     YC       K+DCSS     G       Y   G+++P+F       I+ECN ACSC   C  RVVQ+G++ +L++FRT+ +GWG++ L  I +G F+ EY+GEI++  EA+ R      Q   YLF LD      + +DA   GN+S F+NH C PN+ +  VF  + D+R P +AFFA+ +IKAGEEL F+Y
Sbjct: 1012 SHNSKAWAALQAGRRDRDARNSRL---NQAEQKLLHRDV--------SLGQERVPIPCV---NSVDNEPHPEDYKYISENCVTSPLNIDRNITHLQYCVC-----KEDCSSSICMCGQLSLRCWYDKHGRLLPEFCREEPPLIFECNHACSCWKTCRNRVVQKGLRTRLQLFRTRKKGWGVRALQDIPKGTFVCEYVGEIISEAEADMR------QMDAYLFSLDDKPQDLYCIDARFYGNISRFLNHMCEPNLFACRVFTTHQDLRFPHVAFFASENIKAGEELGFNY 1275
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Medaka
Match: ehmt1b (histone-lysine N-methyltransferase EHMT1 [Source:NCBI gene;Acc:101167635])

HSP 1 Score: 155.992 bits (393), Expect = 1.990e-39
Identity = 102/289 (35.29%), Postives = 156/289 (53.98%), Query Frame = 1 
Query:  484 SHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITD-YVSSSIEIHSDPPIACYCTTSCIDNKKDCSS--IHGGDPP----YTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            SH  K    L   +  +  +NS +   N+  +K++   +        +L  E  P+  V   N+VD E  P D+++I++  V+S + I  +     YC       K+DCSS     G       Y   G+++P+F       I+ECN ACSC   C  RVVQ+G++ +L++FRT+ +GWG++ L  I +G F+ EY+GEI++  EA+ R      Q   YLF LD      + +DA   GN+S F+NH C PN+ +  VF  + D+R P +AFFA+ +IKAGEEL F+Y
Sbjct:  927 SHNSKAWAALQAGRRDRDARNSRL---NQAEQKLLHRDV--------SLGQERVPIPCV---NSVDNEPHPEDYKYISENCVTSPLNIDRNITHLQYCVC-----KEDCSSSICMCGQLSLRCWYDKHGRLLPEFCREEPPLIFECNHACSCWKTCRNRVVQKGLRTRLQLFRTRKKGWGVRALQDIPKGTFVCEYVGEIISEAEADMR------QMDAYLFSLDDKPQDLYCIDARFYGNISRFLNHMCEPNLFACRVFTTHQDLRFPHVAFFASENIKAGEELGFNY 1190
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Medaka
Match: ehmt1b (histone-lysine N-methyltransferase EHMT1 [Source:NCBI gene;Acc:101167635])

HSP 1 Score: 155.992 bits (393), Expect = 2.022e-39
Identity = 102/289 (35.29%), Postives = 156/289 (53.98%), Query Frame = 1 
Query:  484 SHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITD-YVSSSIEIHSDPPIACYCTTSCIDNKKDCSS--IHGGDPP----YTVTGKVIPKFGVP----IYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            SH  K    L   +  +  +NS +   N+  +K++   +        +L  E  P+  V   N+VD E  P D+++I++  V+S + I  +     YC       K+DCSS     G       Y   G+++P+F       I+ECN ACSC   C  RVVQ+G++ +L++FRT+ +GWG++ L  I +G F+ EY+GEI++  EA+ R      Q   YLF LD      + +DA   GN+S F+NH C PN+ +  VF  + D+R P +AFFA+ +IKAGEEL F+Y
Sbjct:  960 SHNSKAWAALQAGRRDRDARNSRL---NQAEQKLLHRDV--------SLGQERVPIPCV---NSVDNEPHPEDYKYISENCVTSPLNIDRNITHLQYCVC-----KEDCSSSICMCGQLSLRCWYDKHGRLLPEFCREEPPLIFECNHACSCWKTCRNRVVQKGLRTRLQLFRTRKKGWGVRALQDIPKGTFVCEYVGEIISEAEADMR------QMDAYLFSLDDKPQDLYCIDARFYGNISRFLNHMCEPNLFACRVFTTHQDLRFPHVAFFASENIKAGEELGFNY 1223
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Planmine SMEST
Match: SMESG000074842.1 (SMESG000074842.1)

HSP 1 Score: 974.926 bits (2519), Expect = 0.000e+0
Identity = 483/485 (99.59%), Postives = 484/485 (99.79%), Query Frame = 1 
Query:   43 MEEFVFCPFTITDKQVKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGXXXXXXXXXINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 1497
            MEEFVFCPFTITDKQVKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDI LPNKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIAC+CTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGSVVSTSTSSINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY
Sbjct:    1 MEEFVFCPFTITDKQVKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIESNVIKIEEDQEYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLINCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHVYKYLPTLLQSKSTKRKKNSDI-LPNKKRKKIVLSTIKKALSDWETLINETYPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACHCTTSCIDNKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGSVVSTSTSSINVNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY 484
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Planmine SMEST
Match: SMESG000045744.1 (SMESG000045744.1)

HSP 1 Score: 109.383 bits (272), Expect = 1.175e-24
Identity = 56/136 (41.18%), Postives = 80/136 (58.82%), Query Frame = 1 
Query:  910 LNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            + C    +QRG +  L +  +   GWG+ T   I++  FI EY GEI++ DEA+ RGK+YD+   ++LF+L    +  F VDA +KGN   F NHS NPN  ++ + +N       RI  FA  +IKAG+EL FDY
Sbjct:  618 ITCKNMAIQRGQRKHLLMSVSDVAGWGIYTKEDIVKNEFIYEYCGEIISQDEADRRGKIYDKTMSSFLFNL----NQSFVVDATRKGNKIRFANHSVNPNCCAKILLVNG----DHRIGIFAKHNIKAGDELFFDY 745
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Planmine SMEST
Match: SMESG000045744.1 (SMESG000045744.1)

HSP 1 Score: 109.383 bits (272), Expect = 1.179e-24
Identity = 56/136 (41.18%), Postives = 80/136 (58.82%), Query Frame = 1 
Query:  910 LNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            + C    +QRG +  L +  +   GWG+ T   I++  FI EY GEI++ DEA+ RGK+YD+   ++LF+L    +  F VDA +KGN   F NHS NPN  ++ + +N       RI  FA  +IKAG+EL FDY
Sbjct:  614 ITCKNMAIQRGQRKHLLMSVSDVAGWGIYTKEDIVKNEFIYEYCGEIISQDEADRRGKIYDKTMSSFLFNL----NQSFVVDATRKGNKIRFANHSVNPNCCAKILLVNG----DHRIGIFAKHNIKAGDELFFDY 741
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Planmine SMEST
Match: SMESG000039925.1 (SMESG000039925.1)

HSP 1 Score: 97.4413 bits (241), Expect = 1.086e-20
Identity = 55/148 (37.16%), Postives = 83/148 (56.08%), Query Frame = 1 
Query:  877 IYECNS-ACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            +YEC+   C    NC  +   R    + ++F T NRGW L+TL  I +G F+ EY+GE++   EA  R K   + N++  + ++  G  +  +DA    N+S F+NHSC+PN+ ++   +N       RI  FA   IKAGEELTF+Y
Sbjct:  772 MYECHPLVCRNGENCRNQRFMRREYPKQEVFSTDNRGWALRTLEPIKKGAFVNEYVGELIDEAEANRRLKKAHETNVSNFYMMELDG--QRIIDAGPAANISRFMNHSCSPNVYTQKWSVNG----DTRIGLFALHTIKAGEELTFNY 913
[Close]
BLAST of Histone-lysine N-methyltransferase vs. Planmine SMEST
Match: SMESG000039925.1 (SMESG000039925.1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.152e-20
Identity = 55/148 (37.16%), Postives = 83/148 (56.08%), Query Frame = 1 
Query:  877 IYECNS-ACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDY 1317
            +YEC+   C    NC  +   R    + ++F T NRGW L+TL  I +G F+ EY+GE++   EA  R K   + N++  + ++  G  +  +DA    N+S F+NHSC+PN+ ++   +N       RI  FA   IKAGEELTF+Y
Sbjct:  787 MYECHPLVCRNGENCRNQRFMRREYPKQEVFSTDNRGWALRTLEPIKKGAFVNEYVGELIDEAEANRRLKKAHETNVSNFYMMELDG--QRIIDAGPAANISRFMNHSCSPNVYTQKWSVNG----DTRIGLFALHTIKAGEELTFNY 928
The following BLAST results are available for this feature:
BLAST of Histone-lysine N-methyltransferase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SUV39H16.363e-7937.67suppressor of variegation 3-9 homolog 1 [Source:HG... [more]
SUV39H17.664e-7937.67suppressor of variegation 3-9 homolog 1 [Source:HG... [more]
SUV39H21.287e-7640.05suppressor of variegation 3-9 homolog 2 [Source:HG... [more]
SUV39H22.688e-7540.56suppressor of variegation 3-9 homolog 2 [Source:HG... [more]
EHMT11.763e-4038.75euchromatic histone lysine methyltransferase 1 [So... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
set-233.873e-2632.67Probable histone-lysine N-methyltransferase set-23... [more]
set-114.670e-2329.88SET (Trithorax/polycomb) domain containing [Sourc... [more]
set-252.189e-2031.55Histone-lysine N-methyltransferase set-25 [Source... [more]
set-231.236e-1831.61Probable histone-lysine N-methyltransferase set-23... [more]
met-17.727e-1835.53Histone-lysine N-methyltransferase [Source:UniPro... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Su(var)3-97.759e-4833.63gene:FBgn0263755 transcript:FBtr0310385[more]
G9a5.802e-3134.56gene:FBgn0040372 transcript:FBtr0332992[more]
G9a5.879e-3134.56gene:FBgn0040372 transcript:FBtr0070063[more]
CG45656.261e-2731.88gene:FBgn0037841 transcript:FBtr0113216[more]
E(z)1.131e-2134.55gene:FBgn0000629 transcript:FBtr0334067[more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
suv39h1b5.559e-7536.57suppressor of variegation 3-9 homolog 1b [Source:Z... [more]
suv39h1b1.016e-7436.57suppressor of variegation 3-9 homolog 1b [Source:Z... [more]
suv39h1a1.736e-7235.58suppressor of variegation 3-9 homolog 1a [Source:N... [more]
ehmt1a1.576e-3936.86euchromatic histone-lysine N-methyltransferase 1a ... [more]
ehmt1b5.652e-3938.82euchromatic histone-lysine N-methyltransferase 1b ... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
suv39h27.996e-7738.44suppressor of variegation 3-9 homolog 2 [Source:NC... [more]
suv39h25.393e-7541.87suppressor of variegation 3-9 homolog 2 [Source:NC... [more]
slc7a2.11.412e-4039.33solute carrier family 7 (cationic amino acid trans... [more]
slc7a2.11.676e-4039.33solute carrier family 7 (cationic amino acid trans... [more]
slc7a2.11.724e-4039.33solute carrier family 7 (cationic amino acid trans... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Suv39h28.763e-7837.85suppressor of variegation 3-9 2 [Source:MGI Symbol... [more]
Suv39h21.197e-7638.20suppressor of variegation 3-9 2 [Source:MGI Symbol... [more]
Suv39h11.271e-7637.44suppressor of variegation 3-9 1 [Source:MGI Symbol... [more]
Suv39h11.703e-7637.44suppressor of variegation 3-9 1 [Source:MGI Symbol... [more]
Ehmt19.032e-4138.33euchromatic histone methyltransferase 1 [Source:MG... [more]
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BLAST of Histone-lysine N-methyltransferase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5RB81|SUV91_PONAB3.056e-7837.67Histone-lysine N-methyltransferase SUV39H1 OS=Pong... [more]
sp|O43463|SUV91_HUMAN3.056e-7837.67Histone-lysine N-methyltransferase SUV39H1 OS=Homo... [more]
sp|Q2NL30|SUV91_BOVIN1.971e-7737.44Histone-lysine N-methyltransferase SUV39H1 OS=Bos ... [more]
sp|Q5F3W5|SUV92_CHICK2.449e-7741.07Histone-lysine N-methyltransferase SUV39H2 OS=Gall... [more]
sp|Q9EQQ0|SUV92_MOUSE2.172e-7637.62Histone-lysine N-methyltransferase SUV39H2 OS=Mus ... [more]
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BLAST of Histone-lysine N-methyltransferase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267DBX93.263e-9936.36Histone-lysine N-methyltransferase OS=Macrostomum ... [more]
A0A1I8J5Y48.209e-9936.56Histone-lysine N-methyltransferase OS=Macrostomum ... [more]
A0A1I8GFF22.185e-9739.54Histone-lysine N-methyltransferase OS=Macrostomum ... [more]
A0A1I8I7P42.251e-9739.54Histone-lysine N-methyltransferase OS=Macrostomum ... [more]
A0A0X3P0793.963e-9635.24Histone-lysine N-methyltransferase OS=Schistocepha... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
suv39h1b5.779e-7740.00suppressor of variegation 3-9 homolog 1b [Source:Z... [more]
suv39h1b6.698e-7736.96suppressor of variegation 3-9 homolog 1b [Source:Z... [more]
suv39h1a1.329e-7144.48histone-lysine N-methyltransferase SUV39H1-A [Sour... [more]
ehmt21.479e-4135.52euchromatic histone-lysine N-methyltransferase 2 [... [more]
ehmt1b3.418e-3938.40euchromatic histone lysine methyltransferase 1 [So... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SUV39H25.683e-7536.34suppressor of variegation 3-9 homolog 2 [Source:HG... [more]
setmar5.311e-3430.56SET domain and mariner transposase fusion gene [So... [more]
ENSPMAT00000004922.16.741e-2530.20pep scaffold:Pmarinus_7.0:GL479351:23010:32607:-1 ... [more]
nsd21.299e-2036.24nuclear receptor binding SET domain protein 2 [Sou... [more]
ENSPMAT00000005461.11.089e-1836.77pep scaffold:Pmarinus_7.0:GL477205:1717:42601:-1 g... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
SET22.269e-1734.21Histone methyltransferase with a role in transcrip... [more]
SET17.117e-1730.90Histone methyltransferase, subunit of the COMPASS ... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO362312.127e-6546.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352773.023e-3842.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO498085.674e-3040.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO437638.112e-3039.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303224.223e-2338.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
suv39h1b9.425e-7938.13suppressor of variegation 3-9 homolog 1 [Source:NC... [more]
setmar3.019e-4034.63histone-lysine N-methyltransferase SETMAR [Source:... [more]
ehmt1b1.546e-3935.29histone-lysine N-methyltransferase EHMT1 [Source:N... [more]
ehmt1b1.990e-3935.29histone-lysine N-methyltransferase EHMT1 [Source:N... [more]
ehmt1b2.022e-3935.29histone-lysine N-methyltransferase EHMT1 [Source:N... [more]
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BLAST of Histone-lysine N-methyltransferase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000074842.10.000e+099.59SMESG000074842.1[more]
SMESG000045744.11.175e-2441.18SMESG000045744.1[more]
SMESG000045744.11.179e-2441.18SMESG000045744.1[more]
SMESG000039925.11.086e-2037.16SMESG000039925.1[more]
SMESG000039925.11.152e-2037.16SMESG000039925.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031607 ID=SMED30031607|Name=Histone-lysine N-methyltransferase|organism=Schmidtea mediterranea sexual|type=transcript|length=1811bp
AAGCTTGGGATAACTAATCTTTATTAAATTTTTTTTTATTCAATGGAAGA
ATTTGTGTTTTGTCCATTTACTATTACTGACAAACAAGTGAAATTAAGTG
ATTACAATATAAACTCTTACAATTTGTTAGAGTTTTTATTTCTCTCATCA
ACTCCGAAAAAAATTGCAAATATATTTAATGAATTAATTGAATCAAACGT
AATAAAAATCGAAGAAGATCAAGAATATGAAGTAGAAGCAATTTTAGACG
AAGCAGAAGAAGATAACGAAAAAGTCTATTTAGTAAAATGGAAAAATTGG
CACATAGAATTCTGCACTTGGGAACCAAAAAAAAATTTAATTAACTGTGA
AGATGAATTTAGAGAATATGAAAAACGGAAATTAGAAAATCGAAAAGGAG
GATTTGTGATCGATTATACACAACCAAAACTTGAATTAATTAATCAAATA
TTTCGTTCGATAACAGAATGCAATGTTAAACCAAGCCATGTCTATAAGTA
TTTGCCAACACTATTACAAAGCAAATCAACGAAACGGAAAAAAAATAGCG
ACATATCATTACCAAATAAAAAACGAAAGAAAATAGTGCTTTCTACTATT
AAAAAGGCTTTATCAGATTGGGAAACATTAATTAATGAAACCTATCCTTT
ATTTAAAGTAACTGTTGAAAATACCGTTGACACTGAAGGCCCACCGCTTG
ATTTCCAGTTTATCACAGATTATGTTAGTAGTAGCATAGAAATCCATTCA
GACCCTCCTATTGCCTGTTATTGCACTACCTCGTGTATTGACAATAAAAA
GGATTGCTCATCAATCCACGGCGGTGACCCCCCTTACACAGTCACGGGAA
AAGTAATCCCGAAATTCGGTGTACCGATATATGAGTGCAATTCCGCCTGT
TCATGTGATTTAAATTGTCCCTATCGAGTAGTTCAGAGAGGGGTCAAGTT
ACAGTTGAAAATTTTCCGCACCAAAAATAGAGGCTGGGGCTTGAAAACTC
TCACCAAAATTATCAGAGGGAATTTTATAATGGAATATCTTGGAGAGATT
GTTGCAGTTGACGAAGCAGAAGAAAGAGGAAAGTTGTATGATCAACAAAA
TTTGACATATCTTTTTGATCTGGATTTCGCCGGTGATCCGGAATTCACAG
TCGATGCATACAAAAAAGGCAACATGTCTCATTTTATTAATCACTCTTGC
AATCCCAATATGACGAGTCGTTGCGTTTTTATAAATAACCTTGACATTAG
AATGCCCAGAATTGCATTTTTCGCCGCTCGGGATATTAAAGCAGGCGAAG
AATTGACATTTGATTATATGATGACAGGAGCTATATCGGATAACAAGGAA
AATGAAGGCTCAGTGGTTAGTACTTCAACATCTTCGATAAATGTTAACAC
AAAATACGAGGCTGGTTCTGAAAGCACAAGTTCTTTACAGATCACAGGTC
GAGTTCCATGCCTATGCAAATCGGAAAAATGCCGAAAATTCTTATATTAA
TAAAACGTATTTTCACTATTATATATTCTGAATATCGATTTTCCAGATCG
AGTCAAAAAATAAGATTACTTACGCATGATTTGAAACGAAATATTGCTAT
TGAAATTATTTTTGTAATGTAAATTTTCATTTTTTCCCTATTATTATTGG
ACAAGTTATTTGTCAATAATATATTATGATACATCTGAAATGTGTGAGCA
AGAATATTGTGTCGGCGGTGGATATTATTGATGTAATCGGCAGATAATGT
GCATTTTTGTTAAATTTTAATTGTGAGTTTTTAATAAAATGTTTTGTGAT
TTAAAAAACAA
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protein sequence of SMED30031607-orf-1

>SMED30031607-orf-1 ID=SMED30031607-orf-1|Name=SMED30031607-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=486bp
MEEFVFCPFTITDKQVKLSDYNINSYNLLEFLFLSSTPKKIANIFNELIE
SNVIKIEEDQEYEVEAILDEAEEDNEKVYLVKWKNWHIEFCTWEPKKNLI
NCEDEFREYEKRKLENRKGGFVIDYTQPKLELINQIFRSITECNVKPSHV
YKYLPTLLQSKSTKRKKNSDISLPNKKRKKIVLSTIKKALSDWETLINET
YPLFKVTVENTVDTEGPPLDFQFITDYVSSSIEIHSDPPIACYCTTSCID
NKKDCSSIHGGDPPYTVTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRG
VKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYD
QQNLTYLFDLDFAGDPEFTVDAYKKGNMSHFINHSCNPNMTSRCVFINNL
DIRMPRIAFFAARDIKAGEELTFDYMMTGAISDNKENEGSVVSTSTSSIN
VNTKYEAGSESTSSLQITGRVPCLCKSEKCRKFLY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006325chromatin organization
GO:0034968histone lysine methylation
GO:0032259methylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000043dorsal ventral margin of the whole animal
PLANA:0000070intestinal phagocyte
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR003616Post-SET_dom
IPR000953Chromo/chromo_shadow_dom
IPR007728Pre-SET_dom
IPR001214SET_dom
IPR023780Chromo_domain
IPR011381Histone_H3-K9_MeTrfase
IPR023779Chromodomain_CS
IPR016197Chromo-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0018024histone-lysine N-methyltransferase activity
GO:0005515protein binding
GO:0046872metal ion binding
GO:0008168methyltransferase activity
GO:0016740transferase activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005694chromosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003616Post-SET domainSMARTSM00508PostSET_3coord: 468..484
e-value: 0.0071
score: 25.6
IPR003616Post-SET domainPROSITEPS50868POST_SETcoord: 468..484
score: 8.495
IPR000953Chromo/chromo shadow domainSMARTSM00298chromo_7coord: 61..114
e-value: 6.3E-12
score: 55.6
IPR000953Chromo/chromo shadow domainPROSITEPS50013CHROMO_2coord: 62..121
score: 13.499
IPR001214SET domainSMARTSM00317set_7coord: 302..431
e-value: 5.5E-37
score: 138.9
IPR001214SET domainPFAMPF00856SETcoord: 313..424
e-value: 4.8E-19
score: 69.4
IPR001214SET domainPROSITEPS50280SETcoord: 302..425
score: 17.748
IPR007728Pre-SET domainSMARTSM00468preset_2coord: 192..286
e-value: 3.6E-5
score: 33.2
IPR007728Pre-SET domainPFAMPF05033Pre-SETcoord: 202..294
e-value: 2.2E-15
score: 57.2
IPR007728Pre-SET domainPROSITEPS50867PRE_SETcoord: 239..299
score: 9.43
NoneNo IPR availableGENE3DG3DSA:2.170.270.10coord: 159..483
e-value: 1.2E-85
score: 289.7
NoneNo IPR availableGENE3DG3DSA:2.40.50.40coord: 56..120
e-value: 3.8E-16
score: 60.5
NoneNo IPR availablePANTHERPTHR46223FAMILY NOT NAMEDcoord: 54..484
NoneNo IPR availableCDDcd00024CD_CSDcoord: 62..111
e-value: 6.16344E-15
score: 66.7317
NoneNo IPR availableSUPERFAMILYSSF82199SET domaincoord: 199..426
IPR011381Histone H3-K9 methyltransferasePIRSFPIRSF009343SUV39_HMTase_SETcoord: 22..484
e-value: 3.0E-108
score: 360.4
IPR023780Chromo domainPFAMPF00385Chromocoord: 62..112
e-value: 2.0E-11
score: 43.6
IPR023779Chromo domain, conserved sitePROSITEPS00598CHROMO_1coord: 79..99
IPR016197Chromo-like domain superfamilySUPERFAMILYSSF54160Chromo domain-likecoord: 52..115