Peptidase S1 domain-containing protein

Overview
NamePeptidase S1 domain-containing protein
Smed IDSMED30031603
Length (bp)476
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Peptidase S1 domain-containing protein (SMED30031603) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Peptidase S1 domain-containing protein (SMED30031603) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30031603

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30031603h1SMcG0005808 SmedASXL_014322SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30031603h1SMcG0005808 dd_Smed_v4_13570_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30031603h1SMcG0005808 dd_Smed_v4_13570_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
anterior sideSMED30031603h1SMcG0005808 dd_Smed_v4_13570_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30031603h1SMcG0005808 dd_Smed_v4_7966_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30031603h1SMcG0005808 dd_Smed_v4_7966_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30031603h1SMcG0005808 dd_Smed_v4_7966_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30031603h1SMcG0005808 dd_Smed_v6_13570_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS2 (transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876])

HSP 1 Score: 83.9593 bits (206), Expect = 4.959e-19
Identity = 54/147 (36.73%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            DIAL+K+ K L F      +    LP    M  P  +Q C   GWG T  +G  SE      + +IE +RC+  YV  YD++      CAG+   +V  C GDSG  LV S NN ++L G  S  SG      PG++  V  F+ WI
Sbjct:  345 DIALMKLQKPLTFNDLVKPVC---LPNPGMMLQP--EQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYV--YDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS2 (transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876])

HSP 1 Score: 83.9593 bits (206), Expect = 4.959e-19
Identity = 54/147 (36.73%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            DIAL+K+ K L F      +    LP    M  P  +Q C   GWG T  +G  SE      + +IE +RC+  YV  YD++      CAG+   +V  C GDSG  LV S NN ++L G  S  SG      PG++  V  F+ WI
Sbjct:  345 DIALMKLQKPLTFNDLVKPVC---LPNPGMMLQP--EQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYV--YDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS15 (transmembrane serine protease 15 [Source:HGNC Symbol;Acc:HGNC:9490])

HSP 1 Score: 84.3445 bits (207), Expect = 5.206e-19
Identity = 51/157 (32.48%), Postives = 80/157 (50.96%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIAS-GTSGTRPGRYPGIFTRVSYFSKWITS 476
            N  + + DIA++ ++ K+ +  Y   I    LP+   +  P   +NC   GWG    QG  +   Q   +P++  +RC +       + N     CAGY +  +  C GDSG  L+C  NN+++LAG+ S G     P R PG++ RVS F++WI S
Sbjct:  869 NRRRKDNDIAMMHLEFKVNYTDYIQPIC---LPEENQVFPPG--RNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM---ICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNR-PGVYARVSRFTEWIQS 1016
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS2 (transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876])

HSP 1 Score: 83.9593 bits (206), Expect = 5.387e-19
Identity = 54/147 (36.73%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            DIAL+K+ K L F      +    LP    M  P  +Q C   GWG T  +G  SE      + +IE +RC+  YV  YD++      CAG+   +V  C GDSG  LV S NN ++L G  S  SG      PG++  V  F+ WI
Sbjct:  345 DIALMKLQKPLTFNDLVKPVC---LPNPGMMLQP--EQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYV--YDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS2 (transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876])

HSP 1 Score: 83.9593 bits (206), Expect = 6.056e-19
Identity = 54/147 (36.73%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            DIAL+K+ K L F      +    LP    M  P  +Q C   GWG T  +G  SE      + +IE +RC+  YV  YD++      CAG+   +V  C GDSG  LV S NN ++L G  S  SG      PG++  V  F+ WI
Sbjct:  382 DIALMKLQKPLTFNDLVKPVC---LPNPGMMLQP--EQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYV--YDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: svh-1 (HGF/MSP/plasminogen-like protein [Source:UniProtKB/TrEMBL;Acc:Q17800])

HSP 1 Score: 67.781 bits (164), Expect = 9.478e-14
Identity = 49/155 (31.61%), Postives = 76/155 (49.03%), Query Frame = 3 
Query:   21 LEYDIALIKVD-KKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGL-ISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNN-KYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
              +DIA++++    +EF  Y   I    LP    +  P   + C+  GWG     GL  +ER Q   +PII +  C  +   +Y S++R   FCAGY +  +  C GDSG    C   +  + LAG+ S   G    + PGI+T V+ +  WI++
Sbjct:  800 FSHDIAILEIPYPGIEFNEYAQPI---CLPSKDFVYTPG--RQCVVSGWG---SMGLRYAERLQAALIPIINRFDCVNS-SQIYSSMSRS-AFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWISA 944
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-1 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q23528])

HSP 1 Score: 61.6178 bits (148), Expect = 8.945e-12
Identity = 42/153 (27.45%), Postives = 67/153 (43.79%), Query Frame = 3 
Query:   24 EYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTP-QGLISERAQTVTLPIIEQKRCSE--TYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIAS-GTSGTRPGRYPGIFTRVSYFSKWI 470
             YD A++++   +        I +  LP          ++ C+  GWG T     L +   + + +P++    CS    Y+G    I+     CAGY    +  C GDSG  L+C+ +  + L G+ S G    RPG  PG++  V   S WI
Sbjct:  143 SYDFAIMRIHPPVNTSTTARPICLPSLPAV-------ENRLCVVTGWGSTIEGSSLSAPTLREIHVPLLSTLFCSSLPNYIG---RIHLPSMLCAGYSYGKIDSCQGDSGGPLMCARDGHWELTGVVSWGIGCARPG-MPGVYGNVHSASTWI 284
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-3 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q94176])

HSP 1 Score: 53.1434 bits (126), Expect = 6.914e-9
Identity = 49/172 (28.49%), Postives = 82/172 (47.67%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMN---WPKTDQNCIFVGWGCTT-------PQGLISERAQTVTLPIIEQKRCSET--YVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNN-KYYLAGI----ASGTSGT-RPGRYPGIFTRVSYFSKWI 470
            N +  + DIAL+++   L      +K+ IK  P  L  +     K  +N + +G+G T        P+ + S+  Q+ ++PII    C +T  ++ +       ++ CAG Y    G   GDSG  L+   +N +Y   GI    A G  G    G++PG++TR+S +  WI
Sbjct:   67 NNQTADNDIALLRISSDL------SKLGIK--PVCLVHDDSKLLKQYKNGVVIGYGLTLGEDSSGEPKLINSQTLQSTSVPIISDDDCVKTWRFLSLLSVKITGYQICAGAYLH--GTAPGDSGGPLLIHKSNGEYVQIGITSYGADGLDGVIDQGKFPGVYTRISKYVPWI 228
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: try-3 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q94176])

HSP 1 Score: 53.1434 bits (126), Expect = 1.034e-8
Identity = 49/172 (28.49%), Postives = 82/172 (47.67%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMN---WPKTDQNCIFVGWGCTT-------PQGLISERAQTVTLPIIEQKRCSET--YVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNN-KYYLAGI----ASGTSGT-RPGRYPGIFTRVSYFSKWI 470
            N +  + DIAL+++   L      +K+ IK  P  L  +     K  +N + +G+G T        P+ + S+  Q+ ++PII    C +T  ++ +       ++ CAG Y    G   GDSG  L+   +N +Y   GI    A G  G    G++PG++TR+S +  WI
Sbjct:  117 NNQTADNDIALLRISSDL------SKLGIK--PVCLVHDDSKLLKQYKNGVVIGYGLTLGEDSSGEPKLINSQTLQSTSVPIISDDDCVKTWRFLSLLSVKITGYQICAGAYLH--GTAPGDSGGPLLIHKSNGEYVQIGITSYGADGLDGVIDQGKFPGVYTRISKYVPWI 278
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: etaTry (gene:FBgn0011554 transcript:FBtr0088163)

HSP 1 Score: 80.4925 bits (197), Expect = 9.198e-19
Identity = 49/155 (31.61%), Postives = 73/155 (47.10%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWIT 473
            N+  ++ DIAL+ VD  L    + T  +I++  +      P         GWG T   GL S++ Q V +PI++ ++C E Y   Y     +   CAG  +     C GDSG  LV ++     LAGI S   G     YPG++  V+Y+  WI 
Sbjct:  113 NSSTMDNDIALVVVDPPLPLDSFSTMEAIEIASEQ-----PAVGVQATISGWGYTKENGLSSDQLQQVKVPIVDSEKCQEAY---YWRPISEGMLCAGLSEGGKDACQGDSGGPLVVANK----LAGIVSWGEGCARPNYPGVYANVAYYKDWIA 255
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: Sb (gene:FBgn0003319 transcript:FBtr0344008)

HSP 1 Score: 76.6406 bits (187), Expect = 9.775e-17
Identity = 53/160 (33.12%), Postives = 77/160 (48.12%), Query Frame = 3 
Query:   24 EYDIALIKVDKKLEFGYYKTKISIKMLPKT----LGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEF------CAGYYDSDVGICTGDSGSGLVC-SHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            EYD+AL+K+++ LEF  + + I    LP+T    +GMN   T       GWG  +  G +    Q V++PI+    C   ++        + EF      CAGY       C GDSG  L   S + +++LAGI S   G      PG+ TR+S F+ WI
Sbjct:  638 EYDLALVKLEQPLEFAPHVSPIC---LPETDSLLIGMNATVT-------GWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRA-----GRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: Sb (gene:FBgn0003319 transcript:FBtr0083250)

HSP 1 Score: 76.6406 bits (187), Expect = 9.775e-17
Identity = 53/160 (33.12%), Postives = 77/160 (48.12%), Query Frame = 3 
Query:   24 EYDIALIKVDKKLEFGYYKTKISIKMLPKT----LGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEF------CAGYYDSDVGICTGDSGSGLVC-SHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            EYD+AL+K+++ LEF  + + I    LP+T    +GMN   T       GWG  +  G +    Q V++PI+    C   ++        + EF      CAGY       C GDSG  L   S + +++LAGI S   G      PG+ TR+S F+ WI
Sbjct:  638 EYDLALVKLEQPLEFAPHVSPIC---LPETDSLLIGMNATVT-------GWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRA-----GRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: tpr (gene:FBgn0034661 transcript:FBtr0071743)

HSP 1 Score: 73.559 bits (179), Expect = 9.080e-16
Identity = 47/156 (30.13%), Postives = 72/156 (46.15%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGL--VCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            NA   + DIA+IK+D+ +EF      + +    ++         +N I  GWG     G  S+  Q V +PI+ Q  C ++  G   + N     C GY +     C GDSG  L  V S   ++ +AG+ S   G     YPG++ RV+ +  WI
Sbjct:  208 NARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSF------KGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNM---LCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG18735 (gene:FBgn0042098 transcript:FBtr0071744)

HSP 1 Score: 70.8626 bits (172), Expect = 8.987e-15
Identity = 51/157 (32.48%), Postives = 73/157 (46.50%), Query Frame = 3 
Query:   18 KLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTD---QNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDS-DVGICTGDSGSGL-VCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWIT 473
              + DIALI+ ++ +  G       I M P  + M  P  +   Q  +  GWG  +  G IS+  Q V +PI+ Q+ C  +  G  +S    +  CAGY +      C GDSG  + V    + Y LAGI S   G      PG++TRV  F+ WI 
Sbjct:  167 NFDSDIALIRFNEPVRLG-------IDMHP--VCMPTPSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYG--ESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIA 312
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: tmprss5 (transmembrane serine protease 5 [Source:ZFIN;Acc:ZDB-GENE-131121-184])

HSP 1 Score: 76.6406 bits (187), Expect = 1.242e-16
Identity = 49/155 (31.61%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQG-LISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N    + DIAL+K+   L F      + +      L    P   Q C   GWG T P   LI E  +   +P+I  K+C+ + +  Y+        CAGY +  V  C GDSG  LVC   N + L G+ S  +G     +PG++++V+ F  WI
Sbjct:  397 NHRTHDNDIALVKLKTPLNFSDTIRPVCLPQYDHDL----PGGTQ-CWISGWGYTQPDDVLIPEVLKEAPVPLISTKKCNSSCM--YNGEITSRMLCAGYSEGKVDACQGDSGGPLVCQDENVWRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWI 544
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: tmprss5 (transmembrane serine protease 5 [Source:ZFIN;Acc:ZDB-GENE-131121-184])

HSP 1 Score: 76.2554 bits (186), Expect = 1.648e-16
Identity = 51/155 (32.90%), Postives = 74/155 (47.74%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQG-LISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N    + DIAL+K+   L F      I    LP+    + P   Q C   GWG T P   LI E  +   +P+I  K+C+ + +  Y+        CAGY +  V  C GDSG  LVC   N + L G+ S  +G     +PG++++V+ F  WI
Sbjct:  397 NHRTHDNDIALVKLKTPLNF---SDTIRPVCLPQ-YDHDLPGGTQ-CWISGWGYTQPDDVLIPEVLKEAPVPLISTKKCNSSCM--YNGEITSRMLCAGYSEGKVDACQGDSGGPLVCQDENVWRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWI 544
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: zmp:0000001088 (zmp:0000001088 [Source:ZFIN;Acc:ZDB-GENE-140106-48])

HSP 1 Score: 73.9442 bits (180), Expect = 3.379e-16
Identity = 54/152 (35.53%), Postives = 73/152 (48.03%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSIN---RKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            DI LIK+   +   Y  + +S+  LP+   M      + C   GWG TT  G IS   +TV LPI+    C+ T     DS N    ++  CAGY       C GDSG  LVC       + GI S  +G    +YPG++T VS F +WI +
Sbjct:  114 DIMLIKLQSPV---YLNSYVSLVPLPRQDAM--VAVGRLCSVSGWGFTTSTGGISSILRTVKLPIVSTAVCNGT-----DSFNGNITENMICAGYSTGGKDACKGDSGGPLVCEGR----VYGIVSWGNGCADAQYPGVYTAVSQFRQWIDA 251
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: CR352265.1 (pep chromosome:GRCz11:24:21813127:21819010:-1 gene:ENSDARG00000062758.6 transcript:ENSDART00000091096.6 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR352265.1)

HSP 1 Score: 73.9442 bits (180), Expect = 4.829e-16
Identity = 45/150 (30.00%), Postives = 67/150 (44.67%), Query Frame = 3 
Query:   24 EYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVC-SHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +YDIAL+++   + F      + +             +  +C   GWG  T +G ++   Q  T+ II    C++    +YD        CAG     V  C GDSG  LVC     +++LAGI S   G      PG++TRV  F+ WI
Sbjct:  148 DYDIALLELSAPVFFNELVQPVCVPAPSHVF-----TSGTSCFVTGWGVLTEEGELATLLQEATVNIINHNTCNK----MYDDAVTPRMLCAGNIQGGVDACQGDSGGPLVCLERGRRWFLAGIVSWGEGCARQNRPGVYTRVIKFTDWI 288
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:55888 (zgc:55888 [Source:ZFIN;Acc:ZDB-GENE-040426-834])

HSP 1 Score: 74.3294 bits (181), Expect = 8.188e-16
Identity = 47/158 (29.75%), Postives = 71/158 (44.94%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISI--KMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            N +  E DIAL+K+   L F  +   I +    LP  +          C   GWG  T  G  + R Q V + + E ++C+  Y G       K   CAG  +  +  C GDSG  L C    +Y LAG+ S   G    + PG++T + ++ +W+ S
Sbjct:  140 NQKTNENDIALLKLQSPLVFSKFVRPIGVFNNDLPPLV---------TCTVTGWGSVTENGPQASRLQEVNVTVYEPQKCNRFYRGKV----LKSMICAGANEGGMDACQGDSGGPLSCFDGERYKLAGVVSWGVGCGRAQKPGVYTTLYHYRQWMVS 284

HSP 2 Score: 52.373 bits (124), Expect = 3.944e-8
Identity = 31/109 (28.44%), Postives = 50/109 (45.87%), Query Frame = 3 
Query:  144 NCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +C+  GWG    +  +  + + + +  ++         G  D  NR+   C     S    C GDSG+ LVC+ N  Y+L G+ +  S     + P +FTRVS +  WI
Sbjct:  451 SCVTTGWG--PRKATLDLQPEILHMARVKPLSEDTCRTGWGDGFNRQSHLCTHAAASTS--CLGDSGAPLVCAKNGIYHLVGLTTWGSKKCQPQKPAVFTRVSAYHSWI 555
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: TMPRSS9 (transmembrane serine protease 9 [Source:NCBI gene;Acc:100489279])

HSP 1 Score: 83.5741 bits (205), Expect = 8.139e-19
Identity = 47/156 (30.13%), Postives = 76/156 (48.72%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLI-SERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            + +  +YD+A++++D  L+F  Y   + +        +      + CI  GWG      L+  E  Q  T+ I++Q  C+     +Y ++  +   CAGY +  +  C GDSG  LVC   + K++LAGI S   G    R PG++ RVS    WI
Sbjct:  133 DPDTADYDVAVLELDSPLKFNKYTQPVCLPDPTHVFPVG-----KKCIITGWGYLKEDNLVKPEVLQKATVAIMDQSLCNS----LYSNVVTERMLCAGYLEGKIDSCQGDSGGPLVCEEPSGKFFLAGIVSWGVGCAEARRPGVYVRVSKIRNWI 279

HSP 2 Score: 73.559 bits (179), Expect = 2.284e-15
Identity = 47/158 (29.75%), Postives = 75/158 (47.47%), Query Frame = 3 
Query:    6 LNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS--ERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHN-NKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
             N   L++D+A++++   L F  Y   + +    +     W      C+  GWG    +G +S  E  Q  ++ II+QK CS     +Y+    +   CAG+ D  V  C GDSG  L C  +   ++LAGI S   G    + PG+++RV+    WI
Sbjct:  424 FNPLTLDFDVAVLELASSLTFNKYVQPVCLPSALQKFPAGW-----KCMISGWG-NIKEGNVSKPEVLQKASVGIIDQKICSV----LYNFSITERMICAGFLDGKVDSCQGDSGGPLACEESPGIFFLAGIVSWGIGCAQAKKPGVYSRVTKLKDWI 571

HSP 3 Score: 67.0106 bits (162), Expect = 5.320e-13
Identity = 45/157 (28.66%), Postives = 73/157 (46.50%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            F N   L+ D+AL+++   L    Y   I    LP  +   +P+  + C   GWG T   G +S + Q  ++ I+  + C +     Y         CAG+    V  C+GD+G  L C   + +++LAGI S   G     +PG++TR++    WI
Sbjct:  739 FYNVYTLDNDVALLELPSPLT---YTNLIRPICLPD-ISHIFPEGTR-CFITGWGSTKEGGAMSRQLQKASVSIVGDQTCKK----FYPIQISPRMLCAGFMQGGVDSCSGDAGGPLACREPSGRWFLAGITSWGYGCARPYFPGVYTRITSVRNWI 886
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: TMPRSS9 (transmembrane serine protease 9 [Source:NCBI gene;Acc:100489279])

HSP 1 Score: 83.5741 bits (205), Expect = 8.162e-19
Identity = 47/156 (30.13%), Postives = 76/156 (48.72%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS-ERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            + +  +YD+A++++D  L+F  Y   + +        +      + CI  GWG      L+  E  Q  T+ I++Q  C+     +Y ++  +   CAGY +  +  C GDSG  LVC   + K++LAGI S   G    R PG++ RVS    WI
Sbjct:  320 DPDTADYDVAVLELDSPLKFNKYTQPVCLPDPTHVFPVG-----KKCIITGWGYLKEDNLVKPEVLQKATVAIMDQSLCNS----LYSNVVTERMLCAGYLEGKIDSCQGDSGGPLVCEEPSGKFFLAGIVSWGVGCAEARRPGVYVRVSKIRNWI 466

HSP 2 Score: 73.559 bits (179), Expect = 2.334e-15
Identity = 47/158 (29.75%), Postives = 75/158 (47.47%), Query Frame = 3 
Query:    6 LNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS--ERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHN-NKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
             N   L++D+A++++   L F  Y   + +    +     W      C+  GWG    +G +S  E  Q  ++ II+QK CS     +Y+    +   CAG+ D  V  C GDSG  L C  +   ++LAGI S   G    + PG+++RV+    WI
Sbjct:  611 FNPLTLDFDVAVLELASSLTFNKYVQPVCLPSALQKFPAGW-----KCMISGWG-NIKEGNVSKPEVLQKASVGIIDQKICSV----LYNFSITERMICAGFLDGKVDSCQGDSGGPLACEESPGIFFLAGIVSWGIGCAQAKKPGVYSRVTKLKDWI 758

HSP 3 Score: 66.6254 bits (161), Expect = 5.928e-13
Identity = 45/157 (28.66%), Postives = 73/157 (46.50%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            F N   L+ D+AL+++   L    Y   I    LP  +   +P+  + C   GWG T   G +S + Q  ++ I+  + C +     Y         CAG+    V  C+GD+G  L C   + +++LAGI S   G     +PG++TR++    WI
Sbjct:  941 FYNVYTLDNDVALLELPSPLT---YTNLIRPICLPD-ISHIFPEGTR-CFITGWGSTKEGGAMSRQLQKASVSIVGDQTCKK----FYPIQISPRMLCAGFMQGGVDSCSGDAGGPLACREPSGRWFLAGITSWGYGCARPYFPGVYTRITSVRNWI 1088
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: dkk2 (dickkopf WNT signaling pathway inhibitor 2 [Source:Xenbase;Acc:XB-GENE-480441])

HSP 1 Score: 80.1073 bits (196), Expect = 1.297e-17
Identity = 50/156 (32.05%), Postives = 76/156 (48.72%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDV-GICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N+E  + DIAL+ +++ LEF  +   + +    + L          C+  GWG T   G  + R Q + LPI++ K C+E+Y   Y      H  CAG+  S     C GDSG  LVC +   +Y++ G+ S   G      PG++T+V  F  WI
Sbjct:  631 NSENYDNDIALLYLEEPLEFNDFLRPVCLPEPEEAL-----TPTSLCVVTGWGNTAEGGQPALRLQQLHLPILDSKICNESY---YPGQMTNHMLCAGFPSSKAKDACQGDSGGPLVCGNTKEQYFIYGLVSWGEGCGQVYKPGVYTKVRLFLTWI 778

HSP 2 Score: 66.6254 bits (161), Expect = 5.957e-13
Identity = 43/136 (31.62%), Postives = 65/136 (47.79%), Query Frame = 3 
Query:   72 YYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLI-SERAQTVTLPIIEQKRCSETYV-GVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWIT 473
            +    +++  LP  +  +W  T   C+  GWG T  +G+I   + Q   +PI+  K+C   +V GV D     +  CAG   +    C GDSG  L+C    +YYL G+ S  S       PG++T  S F  WI+
Sbjct: 1342 HLNNSVAVICLPDGV-TDW--THSECLVAGWGITNVEGMIFPTQLQQAKVPIVSIKKCKNYWVSGVTD-----NNVCAG--KAGATSCMGDSGGPLICKMEERYYLVGVVSWGSSECNVNAPGVYTLTSAFMDWIS 1467

HSP 3 Score: 62.003 bits (149), Expect = 2.366e-11
Identity = 49/163 (30.06%), Postives = 71/163 (43.56%), Query Frame = 3 
Query:   18 KLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNK-YYLAGIASGTSG-------TRPGR----YPGIFTRVSYFSKWI 470
            K+ YDIALI + K + FG     I +  + + L     +    C+  GWG     G +S   Q V LPII    CS     +   +      CAG+ +     C GDSG  LVC   +  ++LAG  S   G        + GR     P I++RVS   +++
Sbjct:  145 KMSYDIALIFLAKPIVFGSQVQPICLPQVGEKL-----EIGTLCVSSGWGRLEENGELSPVLQEVKLPIIGNATCSSVLESMGLPLLDDSMLCAGFPEGGRDACQGDSGGPLVCRRRSGVWFLAGCVSWGVGCGRIWGDKKTGRTQLGSPAIYSRVSSLLEFL 302
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: dkk2 (dickkopf WNT signaling pathway inhibitor 2 [Source:Xenbase;Acc:XB-GENE-480441])

HSP 1 Score: 80.1073 bits (196), Expect = 1.496e-17
Identity = 50/156 (32.05%), Postives = 76/156 (48.72%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDV-GICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N+E  + DIAL+ +++ LEF  +   + +    + L          C+  GWG T   G  + R Q + LPI++ K C+E+Y   Y      H  CAG+  S     C GDSG  LVC +   +Y++ G+ S   G      PG++T+V  F  WI
Sbjct:  613 NSENYDNDIALLYLEEPLEFNDFLRPVCLPEPEEAL-----TPTSLCVVTGWGNTAEGGQPALRLQQLHLPILDSKICNESY---YPGQMTNHMLCAGFPSSKAKDACQGDSGGPLVCGNTKEQYFIYGLVSWGEGCGQVYKPGVYTKVRLFLTWI 760

HSP 2 Score: 66.6254 bits (161), Expect = 7.491e-13
Identity = 43/136 (31.62%), Postives = 65/136 (47.79%), Query Frame = 3 
Query:   72 YYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLI-SERAQTVTLPIIEQKRCSETYV-GVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWIT 473
            +    +++  LP  +  +W  T   C+  GWG T  +G+I   + Q   +PI+  K+C   +V GV D     +  CAG   +    C GDSG  L+C    +YYL G+ S  S       PG++T  S F  WI+
Sbjct: 1305 HLNNSVAVICLPDGV-TDW--THSECLVAGWGITNVEGMIFPTQLQQAKVPIVSIKKCKNYWVSGVTD-----NNVCAG--KAGATSCMGDSGGPLICKMEERYYLVGVVSWGSSECNVNAPGVYTLTSAFMDWIS 1430
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000036430.1 (prostasin-like [Source:NCBI gene;Acc:101734975])

HSP 1 Score: 78.1814 bits (191), Expect = 1.732e-17
Identity = 55/155 (35.48%), Postives = 71/155 (45.81%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS--ERAQTVTLPIIEQKRCSETY------VGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            DIALIK+   ++F  Y   + I     T  + +P    NCI  GWG    Q  +   +  Q V +PII +  C + Y      +  Y SI      CAGY     G C GDSG  LVC  N  + LAGI S   G      PG++T V  +S WI
Sbjct:  119 DIALIKLANPVQFTDYIIPVCIP----TQNVVFPD-GMNCIVSGWGTINQQVSLPYPKTLQKVRVPIIGRASCDQMYHINNPTLPPYQSIIMWDMICAGYKAGRRGSCQGDSGGPLVCPWNGSWLLAGIVSWGFGCAQPNKPGVYTSVPAYSAWI 268
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Klkb1 (kallikrein B, plasma 1 [Source:MGI Symbol;Acc:MGI:102849])

HSP 1 Score: 88.5817 bits (218), Expect = 1.014e-20
Identity = 53/148 (35.81%), Postives = 71/148 (47.97%), Query Frame = 3 
Query:   27 YDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            YDIALIK+   L +  ++  I    LP     N   T  NC   GWG T  QG      Q  T+P++  + C + Y    D +  K   CAGY +     C GDSG  LVC H+ ++ L GI S   G      PG++T+VS +  WI
Sbjct:  482 YDIALIKLQTPLNYTEFQKPIC---LPSKADTNTIYT--NCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKY---RDYVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWI 621
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss9 (transmembrane protease, serine 9 [Source:MGI Symbol;Acc:MGI:3612246])

HSP 1 Score: 81.2629 bits (199), Expect = 3.548e-18
Identity = 51/156 (32.69%), Postives = 79/156 (50.64%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS-ERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +A+  ++D+A++++ + L FG Y   +    LP    +  P   + C+  GWG      L+  E  Q  T+ +++Q  CS  Y   +   +R    CAGY D  V  C GDSG  LVC   + +++LAGI S   G    R PG++TRV+    WI
Sbjct:  321 DADTADFDVAVLELARPLPFGRY---VQPACLPAATHVFPP--GKKCLISGWGYLKEDFLVKPEVLQKATVELLDQSLCSSLYG--HSLTDRM--VCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDWI 467

HSP 2 Score: 69.707 bits (169), Expect = 4.589e-14
Identity = 51/162 (31.48%), Postives = 74/162 (45.68%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWG------CTTPQGLISERAQTVTLPIIEQKRCSETY-VGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHN-NKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N   L++D+AL+++ + L F  Y   I    LP  L ++     + C+  GWG       T P  L     Q  ++ IIEQK C   Y   + D +      CAG+ +  V  C GDSG  L C      +YLAGI S   G    + PG++ R++    WI
Sbjct:  621 NPGILDFDVALLELAQPLVFNKY---IQPVCLP--LAIHKFPVGRKCMISGWGNMQEGNATKPDIL-----QKASVGIIEQKMCGALYNFSLTDRM-----LCAGFLEGRVDSCQGDSGGPLACEETPGVFYLAGIVSWGIGCAQAKKPGVYARITRLKDWI 767

HSP 3 Score: 63.5438 bits (153), Expect = 6.569e-12
Identity = 42/157 (26.75%), Postives = 68/157 (43.31%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            F N   L+YD+AL+++   +        I    LP   G   P     C+  GWG     G ++ + Q   + ++ ++ C   Y     S       CAG+    V  C+GD+G  L C   + ++ L G+ S   G     +PG++TRV+    WI
Sbjct:  947 FYNIYTLDYDVALLELAGPVRRSRLVRPIC---LP---GPARPPDGARCVITGWGSLREGGSMARQLQKAAVRVLSEQTCRRFYPVQISS----RMLCAGFPQGGVDSCSGDAGGPLACREPSGQWVLTGVTSWGYGCGRPHFPGVYTRVAAVLGWI 1093
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss9 (transmembrane protease, serine 9 [Source:MGI Symbol;Acc:MGI:3612246])

HSP 1 Score: 81.2629 bits (199), Expect = 3.548e-18
Identity = 51/156 (32.69%), Postives = 79/156 (50.64%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS-ERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +A+  ++D+A++++ + L FG Y   +    LP    +  P   + C+  GWG      L+  E  Q  T+ +++Q  CS  Y   +   +R    CAGY D  V  C GDSG  LVC   + +++LAGI S   G    R PG++TRV+    WI
Sbjct:  321 DADTADFDVAVLELARPLPFGRY---VQPACLPAATHVFPP--GKKCLISGWGYLKEDFLVKPEVLQKATVELLDQSLCSSLYG--HSLTDRM--VCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDWI 467

HSP 2 Score: 69.707 bits (169), Expect = 4.589e-14
Identity = 51/162 (31.48%), Postives = 74/162 (45.68%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWG------CTTPQGLISERAQTVTLPIIEQKRCSETY-VGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHN-NKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N   L++D+AL+++ + L F  Y   I    LP  L ++     + C+  GWG       T P  L     Q  ++ IIEQK C   Y   + D +      CAG+ +  V  C GDSG  L C      +YLAGI S   G    + PG++ R++    WI
Sbjct:  621 NPGILDFDVALLELAQPLVFNKY---IQPVCLP--LAIHKFPVGRKCMISGWGNMQEGNATKPDIL-----QKASVGIIEQKMCGALYNFSLTDRM-----LCAGFLEGRVDSCQGDSGGPLACEETPGVFYLAGIVSWGIGCAQAKKPGVYARITRLKDWI 767

HSP 3 Score: 63.5438 bits (153), Expect = 6.569e-12
Identity = 42/157 (26.75%), Postives = 68/157 (43.31%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            F N   L+YD+AL+++   +        I    LP   G   P     C+  GWG     G ++ + Q   + ++ ++ C   Y     S       CAG+    V  C+GD+G  L C   + ++ L G+ S   G     +PG++TRV+    WI
Sbjct:  947 FYNIYTLDYDVALLELAGPVRRSRLVRPIC---LP---GPARPPDGARCVITGWGSLREGGSMARQLQKAAVRVLSEQTCRRFYPVQISS----RMLCAGFPQGGVDSCSGDAGGPLACREPSGQWVLTGVTSWGYGCGRPHFPGVYTRVAAVLGWI 1093
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss13 (transmembrane protease, serine 13 [Source:MGI Symbol;Acc:MGI:2682935])

HSP 1 Score: 78.5666 bits (192), Expect = 3.177e-17
Identity = 51/153 (33.33%), Postives = 76/153 (49.67%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQG-LISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            E+ +YDIALI++ K L    +     + M  +T G+N     + C   G+G T       S   + V + +I+ K+C++  V  YDS       CAG        C GDSG  LVC  NN++YLAG+ S  +G      PG++T+V+    WI
Sbjct:  390 EQDDYDIALIRLSKPLTLSAHIHPACLPMHGQTFGLN-----ETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLV--YDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWI 535
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Tmprss2 (transmembrane protease, serine 2 [Source:MGI Symbol;Acc:MGI:1354381])

HSP 1 Score: 77.7962 bits (190), Expect = 5.885e-17
Identity = 46/147 (31.29%), Postives = 68/147 (46.26%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            DIAL+K+   L F      + +      L +     DQ C   GWG T  +G  S+      +P+IE  +C+  Y+  Y+++      CAG+    V  C GDSG  LV   N  ++L G  S  SG      PG++  V+ F+ WI
Sbjct:  343 DIALMKLQTPLAFNDLVKPVCLPNPGMMLDL-----DQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYI--YNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWI 482
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P26262|KLKB1_MOUSE (Plasma kallikrein OS=Mus musculus OX=10090 GN=Klkb1 PE=1 SV=2)

HSP 1 Score: 88.5817 bits (218), Expect = 7.095e-20
Identity = 53/148 (35.81%), Postives = 71/148 (47.97%), Query Frame = 3 
Query:   27 YDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            YDIALIK+   L +  ++  I    LP     N   T  NC   GWG T  QG      Q  T+P++  + C + Y    D +  K   CAGY +     C GDSG  LVC H+ ++ L GI S   G      PG++T+VS +  WI
Sbjct:  482 YDIALIKLQTPLNYTEFQKPIC---LPSKADTNTIYT--NCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKY---RDYVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWI 621
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P14272|KLKB1_RAT (Plasma kallikrein OS=Rattus norvegicus OX=10116 GN=Klkb1 PE=1 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 2.565e-19
Identity = 51/148 (34.46%), Postives = 72/148 (48.65%), Query Frame = 3 
Query:   27 YDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            YDIALIK+   L +  ++  I    LP     N   T  NC   GWG T  +G      Q  T+P++  + C + Y    D +  K   CAGY +  +  C GDSG  LVC H+ ++ L GI S   G      PG++T+V+ +  WI
Sbjct:  482 YDIALIKLQTPLNYTEFQKPIC---LPSKADTNTIYT--NCWVTGWGYTKERGETQNILQKATIPLVPNEECQKKY---RDYVITKQMICAGYKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKEQPGVYTKVAEYIDWI 621
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P54629|TRYU_DROER (Trypsin eta OS=Drosophila erecta OX=7220 GN=etaTry PE=3 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.482e-18
Identity = 51/158 (32.28%), Postives = 73/158 (46.20%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
              NA  ++ DIAL+ VD  L      T  +I++  +      P         GWG T   GL S++ Q V +P+++ ++C E Y   Y     +   CAG  +     C GDSG  LV ++     LAGI S   G     YPG++  V+YF  WI S
Sbjct:  111 LYNATIMDNDIALVIVDPPLPLASSSTMEAIEIAAEQ-----PAVGVQATISGWGYTKENGLSSDQLQQVNVPVVDSEKCQEAY---YWRPISEGMLCAGLSEGGKDACQGDSGGPLVVANK----LAGIVSWGEGCARPNYPGVYANVAYFKDWIAS 256
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|O15393|TMPS2_HUMAN (Transmembrane protease serine 2 OS=Homo sapiens OX=9606 GN=TMPRSS2 PE=1 SV=3)

HSP 1 Score: 83.9593 bits (206), Expect = 2.381e-18
Identity = 54/147 (36.73%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            DIAL+K+ K L F      +    LP    M  P  +Q C   GWG T  +G  SE      + +IE +RC+  YV  YD++      CAG+   +V  C GDSG  LV S NN ++L G  S  SG      PG++  V  F+ WI
Sbjct:  345 DIALMKLQKPLTFNDLVKPVC---LPNPGMMLQP--EQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYV--YDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
[Close]
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P98073|ENTK_HUMAN (Enteropeptidase OS=Homo sapiens OX=9606 GN=TMPRSS15 PE=1 SV=3)

HSP 1 Score: 84.3445 bits (207), Expect = 2.500e-18
Identity = 51/157 (32.48%), Postives = 80/157 (50.96%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIAS-GTSGTRPGRYPGIFTRVSYFSKWITS 476
            N  + + DIA++ ++ K+ +  Y   I    LP+   +  P   +NC   GWG    QG  +   Q   +P++  +RC +       + N     CAGY +  +  C GDSG  L+C  NN+++LAG+ S G     P R PG++ RVS F++WI S
Sbjct:  869 NRRRKDNDIAMMHLEFKVNYTDYIQPIC---LPEENQVFPPG--RNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM---ICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNR-PGVYARVSRFTEWIQS 1016
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A3S5CJI8 (Peptidase S1 domain-containing protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS6908 PE=4 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 2.424e-43
Identity = 69/152 (45.39%), Postives = 94/152 (61.84%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            + LE+DIALIK+   L+        S+++ P     NWPK  + C+ VGWGCT   G  S  AQ     ++  K CS+ Y      +N  HEFCAGYY++++GIC GDSGSGLVC+    +YL G+AS T  T+P ++PG+FTRVS+F  WI
Sbjct:   39 DDLEWDIALIKLSVPLDLARMIEVSSVRLPPTVQPENWPKAGEVCVLVGWGCTRVDGGPSTHAQMARFQVVANKDCSQMYQH-NAGLNEHHEFCAGYYNANLGICPGDSGSGLVCNREGLWYLIGVASATHATKPSKFPGLFTRVSHFRGWI 189
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A183W161 (Peptidase S1 domain-containing protein OS=Trichobilharzia regenti OX=157069 PE=4 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 6.855e-39
Identity = 69/152 (45.39%), Postives = 89/152 (58.55%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            + LEYD+A++++D  L       +++ ++ P    M WP     CIFVGWGC    G  S  AQ V L  +    CS  Y G    +N  HEFCAGYY   VGIC+GDSGSGL+   ++K Y+ G+AS T  T P  YPG+FTRVSYF  WI
Sbjct:   13 DDLEYDLAVLELDAPLPLEDPGVQLA-ELPPSEYYMTWPPESAECIFVGWGCRAKHGKPSAEAQVVHLTTLTNDDCSLLY-GHAAGLNDNHEFCAGYYQGRVGICSGDSGSGLIYKKDDKNYVVGVASATHATAPELYPGLFTRVSYFRDWI 162
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A3P8LM66 (Peptidase S1 domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS6467 PE=4 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 7.006e-39
Identity = 69/152 (45.39%), Postives = 89/152 (58.55%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            + LEYD+A++++D  L       +++ ++ P    M WP     CIFVGWGC    G  S  AQ V L  +    CS  Y G    +N  HEFCAGYY   VGIC+GDSGSGL+   ++K Y+ G+AS T  T P  YPG+FTRVSYF  WI
Sbjct:   13 DDLEYDLAVLELDAPLPLEDPGVQLA-ELPPSEYYMTWPPESAECIFVGWGCRAKHGKPSAEAQVVHLTTLTNDDCSLLY-GHAAGLNDNHEFCAGYYQGRVGICSGDSGSGLIYKKDDKNYVVGVASATHATAPELYPGLFTRVSYFRDWI 162
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A183LRV2 (Peptidase S1 domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS6527 PE=3 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 2.789e-38
Identity = 68/152 (44.74%), Postives = 89/152 (58.55%), Query Frame = 3 
Query:   21 LEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            LEYDIAL K+ +            I++  K +G  WPK +Q C+ VGWGC+   G  + + Q V LPI++ K C   Y   Y ++  +HEFCAGY++   G+C GDSG  LVC  + +Y LAGI S T    P  YP IFTRVSYF+KWI  
Sbjct:   44 LEYDIALFKLKETPVLWKINHLDLIELPDKKIGEEWPKPNQKCVAVGWGCSFVDGPPTLKIQAVELPILQSKTCMSMY-SAYINLTEEHEFCAGYHNFGKGVCPGDSGGPLVCEDDGEYRLAGIVSATHSKLPADYPAIFTRVSYFAKWIND 194
[Close]
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A183QKR2 (Peptidase S1 domain-containing protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 5.899e-38
Identity = 69/152 (45.39%), Postives = 92/152 (60.53%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            + LEYD+ALI+++  L       + + ++ P    + WP    +CIFVGWGC    G  S +AQ V L  ++ + CS  Y G    +N  HEFCAGYY   VGIC+GDSGSGL+   + K+Y+ G+AS T  T P  YPG+FTRVSYF  WI
Sbjct:   28 DDLEYDLALIELENPLPSEDPGVQPA-ELPPSENYLAWPADHADCIFVGWGCRVKNGRPSAQAQAVHLLTLKNQDCSLMY-GNAAGLNDHHEFCAGYYQGRVGICSGDSGSGLIYMKDKKHYVVGVASATHATAPELYPGLFTRVSYFRAWI 177
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: tmprss5 (transmembrane serine protease 5 [Source:ZFIN;Acc:ZDB-GENE-131121-184])

HSP 1 Score: 76.6406 bits (187), Expect = 4.734e-17
Identity = 50/155 (32.26%), Postives = 75/155 (48.39%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGL-ISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N    + DIAL+K+   L F      I    LP+    + P   Q C   GWG T P  + I +  +   +P+I  K+C+ +   +Y+        CAGY +  V  C GDSG  LVC  +N + L G+ S  +G     +PG++T+V+ F  WI
Sbjct:  114 NHRSHDNDIALMKLRTPLNF---SDTIRPACLPQ-YDHDLPGGTQ-CWISGWGYTQPDDVHIPDTLKEAPVPLISTKKCNSS--CMYNGEITSRMLCAGYTEGKVDACQGDSGGPLVCQDDNVWRLVGVVSWGTGCAEPNHPGVYTKVAEFLGWI 261
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: zmp:0000001088 (trypsin-like [Source:NCBI gene;Acc:103044589])

HSP 1 Score: 76.2554 bits (186), Expect = 4.978e-17
Identity = 51/155 (32.90%), Postives = 70/155 (45.16%), Query Frame = 3 
Query:    6 LNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
             N      DI LIK+   +    Y T   +     ++        + C   GWG TTP G I    +TV LPI+ +  C+ T    Y+    +   CAGY D     C+GDSG  LVC       + GI S  +G    +YPG++T V+ F KWI
Sbjct:  105 FNQNTNNADIMLIKLQSPVIVNSYVTTAPLPRQNASI-----SEGRVCSVSGWGFTTPSGGIPTTLRTVALPIVSESWCNST--DSYNGNITELMICAGYTDGGKDACSGDSGGPLVCEGR----VYGIVSWGTGCADAQYPGVYTSVAKFRKWI 248
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000049564.1 (coagulation factor X-like [Source:NCBI gene;Acc:103041525])

HSP 1 Score: 77.411 bits (189), Expect = 6.913e-17
Identity = 46/153 (30.07%), Postives = 80/153 (52.29%), Query Frame = 3 
Query:   21 LEYDIALIKVDKKLEFGYYKTKISI--KMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIAS-GTSGTRPGRYPGIFTRVSYFSKWI 470
             + D+AL+ + + +EF    +   +    L + L MN     Q  +  GWG T+  G  S   + V LP+I+Q+ C ++     + +   + FCAG+  +++  CTGDSG   V ++   ++L G+ S G      G+Y G++TR+S F +WI
Sbjct:  319 FDSDVALLYLSQPVEFSSVASPACLPNAALAQVLMMN----GQRGLVTGWGATSFMGRSSRFLRKVVLPVIDQQECMQST----EQVVTDNMFCAGFLQAEMDACTGDSGGPFVVNYRGTWFLTGVVSWGEKCAAEGKY-GVYTRLSNFLQWI 462
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000003105.2 (coagulation factor X-like [Source:NCBI gene;Acc:103041525])

HSP 1 Score: 77.0258 bits (188), Expect = 8.753e-17
Identity = 46/153 (30.07%), Postives = 80/153 (52.29%), Query Frame = 3 
Query:   21 LEYDIALIKVDKKLEFGYYKTKISI--KMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIAS-GTSGTRPGRYPGIFTRVSYFSKWI 470
             + D+AL+ + + +EF    +   +    L + L MN     Q  +  GWG T+  G  S   + V LP+I+Q+ C ++     + +   + FCAG+  +++  CTGDSG   V ++   ++L G+ S G      G+Y G++TR+S F +WI
Sbjct:  313 FDSDVALLYLSQPVEFSSVASPACLPNAALAQVLMMN----GQRGLVTGWGATSFMGRSSRFLRKVVLPVIDQQECMQST----EQVVTDNMFCAGFLQAEMDACTGDSGGPFVVNYRGTWFLTGVVSWGEKCAAEGKY-GVYTRLSNFLQWI 456
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000036517.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:21871702:21873022:1 gene:ENSAMXG00000043708.1 transcript:ENSAMXT00000036517.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.7886 bits (177), Expect = 2.506e-16
Identity = 47/160 (29.38%), Postives = 71/160 (44.38%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVC--SHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            + NA   +YDIAL+++ K            + +   +L ++       C   GWG  + Q ++    Q   + I+ Q  C  TY  V   +      CAG    +   C GDSG  L C  S   +++L GI S  SG     +PG++TRV+ F  WI S
Sbjct:   21 YYNARTFDYDIALLQLRKAWPSNLASFIQPVCLPSASLTLS---DGHRCWVTGWGYRSEQKVLPTVLQKAEVNIMSQSECKRTYGPVSPRM-----LCAGVPSGEQDACRGDSGGPLACRVSLGGRWFLTGIVSWGSGCGRPNFPGVYTRVAKFIDWINS 172
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001315.1 (pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-1 gene:ENSPMAG00000001180.1 transcript:ENSPMAT00000001315.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 1.490e-17
Identity = 52/153 (33.99%), Postives = 71/153 (46.41%), Query Frame = 3 
Query:   24 EYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGL-ISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICT-GDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            +YDIAL+++D  +       ++    +P       P   Q C   GWG        +S   Q V LP+I Q  C    +G YD    +   CAGY D     C  GDSG  LVC     ++LAG+ S   G      PG++TRV+ F+KWI S
Sbjct:  182 DYDIALLELDSPVNL---TEQVQTVCMPAASHAFLPG--QMCWVSGWGTVIGNEFSLSNNMQEVQLPLISQSDC----IGSYDHATPRM-LCAGYPDGGKDACQQGDSGGPLVCEDRGSWFLAGLVSWGVGCGLVNKPGVYTRVTAFTKWINS 324
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: tmprss3a (transmembrane serine protease 3a [Source:ZFIN;Acc:ZDB-GENE-070912-70])

HSP 1 Score: 70.0922 bits (170), Expect = 3.873e-15
Identity = 47/162 (29.01%), Postives = 69/162 (42.59%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPK-----TLGMNWPKTDQNCIFVGWGCT-TPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +++    +YDIAL+K+ K L        I    LP       +GMN       C   GWG T    G  S   Q V +PI+  + C+      Y+        CAG+       C GDSG  LVC     +++ G  S   G     +PG+++RV+ +  WI
Sbjct:  196 YVDNTNNDYDIALVKLSKPLSM---SNTIGPACLPNYQTDFQVGMN-------CWITGWGATKVSAGPASTTLQEVMVPILSTETCNA--ANSYNGQITSRMVCAGFMQGGQDACQGDSGGPLVCQTGTTWFVVGATSFGEGCALTNFPGVYSRVTAYLDWI 345
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007252.1 (pep scaffold:Pmarinus_7.0:GL477828:77502:80240:-1 gene:ENSPMAG00000006546.1 transcript:ENSPMAT00000007252.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.0106 bits (162), Expect = 1.203e-14
Identity = 52/152 (34.21%), Postives = 74/152 (48.68%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHN-NKYYLAGIASGTS--GTRPGRYPGIFTRVSYFSKWITS 476
            DIALI++ K +       K+ +  LP   G+  P  +  C   GWG     G + +  Q   LP+++   CS+     + S  + +  CAG    D G C GDSG  L C ++  K+ + GIAS  S  G    R P +FTRVS F+ WI S
Sbjct:   53 DIALIRLVKPVTL---TNKVQLSCLPPA-GLVLPN-NYVCYITGWGRIATGGALPDALQQANLPVVDHATCSQP--SWWSSTVQTNMVCAGGDGYDAG-CNGDSGGPLNCINSAGKWEVHGIASFVSSMGCNYIRKPTVFTRVSAFNDWIDS 196
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006839.1 (pep scaffold:Pmarinus_7.0:GL478004:17964:21571:1 gene:ENSPMAG00000006178.1 transcript:ENSPMAT00000006839.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 3.990e-14
Identity = 53/153 (34.64%), Postives = 75/153 (49.02%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRK-HEFCAGYYDSDVGICTGDSGSGLVCSHN-NKYYLAGIASGTS--GTRPGRYPGIFTRVSYFSKWITS 476
            DIALI++ + +       K+ +  LP   G+  P  D  C   GWG  +  G + +  Q   LP+++   CS+     + S N K +  CAG    D G C GDSG  L C ++  K+ + GI S  S  G    R P +FTRVS F+ WI S
Sbjct:   48 DIALIRLAQPVVL---SNKVQLSCLPPA-GLVLPH-DSPCYITGWGRLSTGGALPDALQQANLPVVDHATCSQPS---WWSTNAKTNMVCAGGDGYDSG-CNGDSGGPLNCINSAGKWEVHGITSYVSSMGCNYIRKPTVFTRVSAFNDWIDS 191
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006889.1 (pep scaffold:Pmarinus_7.0:GL476534:609000:610491:1 gene:ENSPMAG00000006219.1 transcript:ENSPMAT00000006889.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 7.060e-14
Identity = 49/157 (31.21%), Postives = 71/157 (45.22%), Query Frame = 3 
Query:   24 EYDIALIKVDKKLEFGYYKTKISIKMLP---KTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSH-NNKYYLAGIASGTS--GTRPGRYPGIFTRVSYFSKWITS 476
             YDIA+ K+   +      +K+ +  LP   + L  N+P     C   GWG     G      Q  +LP+++   CS+     + S  R    CAG   S    C GD G  L C   +N + + GIAS  S  G    R P +FTRVS ++ WI++
Sbjct:    1 RYDIAMFKIASPVAL---SSKVRLACLPSANQILPNNYP-----CYATGWGSLDTSGPFPSALQQASLPVVDYATCSQP--SWWGSSLRSSVICAG--GSTRSACYGDGGGPLNCQRWDNAWVVQGIASYVSSLGCNTIRKPTVFTRVSAYNSWISA 145
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO42420 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1T0])

HSP 1 Score: 80.4925 bits (197), Expect = 3.652e-19
Identity = 48/151 (31.79%), Postives = 75/151 (49.67%), Query Frame = 3 
Query:   30 DIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVG-VYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIAS-GTSGTRPGRYPGIFTRVSYFSKWITS 476
            DIAL+K+D+  +   Y   ++   LP  +    PK    C   GWG  +  G   +  Q  T+P++ + RC + Y G +++S+      CAG     V  C GDSG  +VC +  ++Y+ G  S G     PG++ G++ RV Y   WI S
Sbjct:  108 DIALLKLDRPAKLDRY---VNFACLPDQVPE--PKEGDRCYITGWGKLSSHGSAPDILQQATVPVVGRARCMKAYRGQIHESM-----LCAGLDAGGVDACQGDSGGPMVCENAGRFYIQGATSWGNGCAAPGKF-GVYARVKYVLDWIKS 247
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO43454 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYF8])

HSP 1 Score: 77.0258 bits (188), Expect = 5.329e-18
Identity = 46/151 (30.46%), Postives = 70/151 (46.36%), Query Frame = 3 
Query:   21 LEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGT-SGTRPGRYPGIFTRVSYFSKWI 470
            L+YDIAL+K+ + + F  Y +++ +       G         C   GWG        S   Q  ++P+++Q+ C E Y  +     R    CAG Y +  G C GDSG  LVC    ++ L G+ S + +G     Y G++  V YF  WI
Sbjct:   89 LDYDIALLKLRQPITFNAYVSQVCLPQAALLAGTP-------CYVSGWGRIGESSPGSNVLQEASIPLVDQRACEEQYRNLKPITARMR--CAGIYGTPKGTCKGDSGGPLVCESKGRWVLMGVTSWSYNGCADSGYAGVYADVVYFKDWI 230
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO39623 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9K4])

HSP 1 Score: 76.6406 bits (187), Expect = 6.952e-18
Identity = 47/152 (30.92%), Postives = 74/152 (48.68%), Query Frame = 3 
Query:   18 KLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVG-VYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +  YDIAL+K+ K  E   +   I++  LP   GM  P     C   GWG  +P G      +  ++PI+ + RC  TY   ++DS+      CAGY    +  C GDSG  +VC    +++L G+ S   G       G++++V++   WI
Sbjct:   87 RYAYDIALLKLRKPAELNKF---INLVCLPH--GMQIPAEHTKCWITGWGRLSPGGWAPINLRQASVPIVSRARCEVTYPKRLHDSM-----LCAGYDQGGIDSCQGDSGGPMVCESGGRFFLHGVTSWGVGCGFRGNFGVYSKVTHSLGWI 228
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO46103 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR41])

HSP 1 Score: 76.2554 bits (186), Expect = 1.008e-17
Identity = 46/151 (30.46%), Postives = 70/151 (46.36%), Query Frame = 3 
Query:   21 LEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGT-SGTRPGRYPGIFTRVSYFSKWI 470
            L+YDIAL+K+ + + F  Y +++ +       G         C   GWG        S   Q  ++P+++Q+ C E Y  +     R    CAG Y +  G C GDSG  LVC    ++ L G+ S + +G     Y G++  V YF  WI
Sbjct:   73 LDYDIALLKLRQPITFNAYVSQVCLPQDALLAGTP-------CYVSGWGRIGESSPGSNVLQEASIPLVDQRACEEQYRNLKPITARMR--CAGIYGTPKGTCKGDSGGPLVCESKGRWVLMGVTSWSYNGCADSGYAGVYADVVYFKDWI 214
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO38900 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN0])

HSP 1 Score: 73.559 bits (179), Expect = 2.344e-16
Identity = 53/160 (33.12%), Postives = 78/160 (48.75%), Query Frame = 3 
Query:    3 FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVT---LPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSG-TRPGRYPGIFTRVSYFSKWI 470
            ++  +  ++D+ALIK+ K   F    TK+S   LPK   +   K  +NC   GWG      L+  RA+ +     PI++ + C        D I+++   CAG   + V  C GDSG  LVC  +  + L G AS  S  T PG+   I+ RVS +  WI
Sbjct:  109 YVGGKDKKHDLALIKLAKPATF---STKVSPVCLPKQGDLM--KERENCFATGWG-RVSSSLLHSRAKKLQQGKAPIVDHQTCIRKISQWKDGIDQQSMVCAGGAGNSV--CHGDSGGPLVCEESGHWVLRGAASWVSSMTCPGKKYAIYVRVSSYIDWI 260
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: tmprss5 (transmembrane serine protease 5 [Source:NCBI gene;Acc:101167385])

HSP 1 Score: 73.1738 bits (178), Expect = 2.494e-16
Identity = 50/155 (32.26%), Postives = 74/155 (47.74%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS-ERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N    + DIALIK+   L F      I    LP+    + P   Q C   GWG T P  + S +  +   +P+I  K+C+ +   +Y+        CAGY +  V  C GDSG  LVC  +  + L G+ S  +G     +PG++T+V+ F  WI
Sbjct:   48 NHRTHDSDIALIKLRTPLNF---TDTIRPICLPQ-YKYDLPGGTQ-CWISGWGYTKPDDVQSPDTLKEAPVPLISTKKCNSS--CMYNGEITPRMLCAGYTEGKVDACQGDSGGPLVCQEDTVWRLVGVVSWGTGCAEPNHPGVYTKVAEFLSWI 195
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000009057.2 (transmembrane protease serine 4 [Source:NCBI gene;Acc:101166070])

HSP 1 Score: 74.7146 bits (182), Expect = 4.583e-16
Identity = 48/153 (31.37%), Postives = 75/153 (49.02%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFV-GWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            EK ++DIALI++   +    Y+  + +   PK LG+     +Q+ + V GWG    +G +S   Q   +P+I+   CS +   +Y S   +   CAGY +  V  C GDSG  LV    +++ L G+ S   G      PG++T V     WI
Sbjct:  305 EKQDFDIALIRLSSPITVRDYQKPVCLP--PKDLGL----ANQSPLAVTGWGYREEEGTVSSTLQEADVPLIDWTTCSSS--SLYGSFLTRRMICAGYTEGKVDACKGDSGGPLVYFLPHQWTLVGVVSWGIGCARANKPGVYTNVDEMLNWI 449
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000034247.1 (transmembrane protease serine 4 [Source:NCBI gene;Acc:101166070])

HSP 1 Score: 74.7146 bits (182), Expect = 5.339e-16
Identity = 48/153 (31.37%), Postives = 75/153 (49.02%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFV-GWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            EK ++DIALI++   +    Y+  + +   PK LG+     +Q+ + V GWG    +G +S   Q   +P+I+   CS +   +Y S   +   CAGY +  V  C GDSG  LV    +++ L G+ S   G      PG++T V     WI
Sbjct:  305 EKQDFDIALIRLSSPITVRDYQKPVCLP--PKDLGL----ANQSPLAVTGWGYREEEGTVSSTLQEADVPLIDWTTCSSS--SLYGSFLTRRMICAGYTEGKVDACKGDSGGPLVYFLPHQWTLVGVVSWGIGCARANKPGVYTNVDEMLNWI 449
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000042683.1 (pep primary_assembly:ASM223467v1:8:2747794:2749967:-1 gene:ENSORLG00000030405.1 transcript:ENSORLT00000042683.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.9442 bits (180), Expect = 5.392e-16
Identity = 48/158 (30.38%), Postives = 75/158 (47.47%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTL--GMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            N+   + DIAL+++  ++ F  Y T + +     T   G+N   T    I  G     PQ L     Q V +PI+  ++C  +Y  + D++      CAG        C GDSG  LV   NN++  AG+ S  +G     +PG++TRVS +  WI +
Sbjct:   53 NSVTADNDIALLQLSSQVTFNNYITPVCLPSTNSTFYSGVNTWVTGWGNIGTGVSLPAPQTL-----QEVQVPIVGNRQCKCSYSSITDNM-----VCAGLLAGGKDSCQGDSGGPLVIKQNNRWIQAGVVSFGNGCALPHFPGVYTRVSQYQTWINT 200
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: tmprss5 (transmembrane serine protease 5 [Source:NCBI gene;Acc:101167385])

HSP 1 Score: 72.7886 bits (177), Expect = 6.825e-16
Identity = 49/155 (31.61%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLIS-ERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            N    + DIALIK+   L F      I +      L    P   Q C   GWG T P  + S +  +   +P+I  K+C+ +   +Y+        CAGY +  V  C GDSG  LVC  +  + L G+ S  +G     +PG++T+V+ F  WI
Sbjct:   95 NHRTHDSDIALIKLRTPLNFTDTIRPICLPQYKYDL----PGGTQ-CWISGWGYTKPDDVQSPDTLKEAPVPLISTKKCNSS--CMYNGEITPRMLCAGYTEGKVDACQGDSGGPLVCQEDTVWRLVGVVSWGTGCAEPNHPGVYTKVAEFLSWI 242
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000072099.1 (SMESG000072099.1)

HSP 1 Score: 327.791 bits (839), Expect = 4.157e-112
Identity = 154/156 (98.72%), Postives = 155/156 (99.36%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            N EKLEYDIALIKVDKKLEFGYYKTKI+IKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS
Sbjct:  343 NPEKLEYDIALIKVDKKLEFGYYKTKINIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 498
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000072099.1 (SMESG000072099.1)

HSP 1 Score: 327.405 bits (838), Expect = 4.228e-112
Identity = 154/156 (98.72%), Postives = 155/156 (99.36%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            N EKLEYDIALIKVDKKLEFGYYKTKI+IKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS
Sbjct:  341 NPEKLEYDIALIKVDKKLEFGYYKTKINIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 496
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000072099.1 (SMESG000072099.1)

HSP 1 Score: 325.865 bits (834), Expect = 3.695e-111
Identity = 154/156 (98.72%), Postives = 155/156 (99.36%), Query Frame = 3 
Query:    9 NAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 476
            N EKLEYDIALIKVDKKLEFGYYKTKI+IKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS
Sbjct:  362 NPEKLEYDIALIKVDKKLEFGYYKTKINIKMLPKTLGMNWPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWITS 517
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000012752.1 (SMESG000012752.1)

HSP 1 Score: 148.673 bits (374), Expect = 2.090e-44
Identity = 76/153 (49.67%), Postives = 92/153 (60.13%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMN-WPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +++E+DIAL+K+   +E  Y    + +  LP       WPK  Q CI +GWGC T  G ISERAQ   L I   K C + Y    D +N +HEFCAG Y S  G+C GDSGSGL C   NK+ LAG+AS T    PG YPGIFTRVSYF  WI
Sbjct:  160 DEIEWDIALMKLQSPIEEKYLNEFLEVIPLPSEADSKPWPKIGQMCILIGWGCKTNGGSISERAQIANLKIQSNKFCEKVYNQGAD-LNDEHEFCAGKYKSGHGLCEGDSGSGLACKKGNKWTLAGVASATHAELPGNYPGIFTRVSYFISWI 311
[Close]
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000012752.1 (SMESG000012752.1)

HSP 1 Score: 148.673 bits (374), Expect = 2.163e-44
Identity = 76/153 (49.67%), Postives = 92/153 (60.13%), Query Frame = 3 
Query:   15 EKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMN-WPKTDQNCIFVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAGYYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVSYFSKWI 470
            +++E+DIAL+K+   +E  Y    + +  LP       WPK  Q CI +GWGC T  G ISERAQ   L I   K C + Y    D +N +HEFCAG Y S  G+C GDSGSGL C   NK+ LAG+AS T    PG YPGIFTRVSYF  WI
Sbjct:  161 DEIEWDIALMKLQSPIEEKYLNEFLEVIPLPSEADSKPWPKIGQMCILIGWGCKTNGGSISERAQIANLKIQSNKFCEKVYNQGAD-LNDEHEFCAGKYKSGHGLCEGDSGSGLACKKGNKWTLAGVASATHAELPGNYPGIFTRVSYFISWI 312
The following BLAST results are available for this feature:
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMPRSS24.959e-1936.73transmembrane serine protease 2 [Source:HGNC Symbo... [more]
TMPRSS24.959e-1936.73transmembrane serine protease 2 [Source:HGNC Symbo... [more]
TMPRSS155.206e-1932.48transmembrane serine protease 15 [Source:HGNC Symb... [more]
TMPRSS25.387e-1936.73transmembrane serine protease 2 [Source:HGNC Symbo... [more]
TMPRSS26.056e-1936.73transmembrane serine protease 2 [Source:HGNC Symbo... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
svh-19.478e-1431.61HGF/MSP/plasminogen-like protein [Source:UniProtK... [more]
try-18.945e-1227.45TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
try-36.914e-928.49TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
try-31.034e-828.49TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
etaTry9.198e-1931.61gene:FBgn0011554 transcript:FBtr0088163[more]
Sb9.775e-1733.13gene:FBgn0003319 transcript:FBtr0344008[more]
Sb9.775e-1733.13gene:FBgn0003319 transcript:FBtr0083250[more]
tpr9.080e-1630.13gene:FBgn0034661 transcript:FBtr0071743[more]
CG187358.987e-1532.48gene:FBgn0042098 transcript:FBtr0071744[more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmprss51.242e-1631.61transmembrane serine protease 5 [Source:ZFIN;Acc:Z... [more]
tmprss51.648e-1632.90transmembrane serine protease 5 [Source:ZFIN;Acc:Z... [more]
zmp:00000010883.379e-1635.53zmp:0000001088 [Source:ZFIN;Acc:ZDB-GENE-140106-48... [more]
CR352265.14.829e-1630.00pep chromosome:GRCz11:24:21813127:21819010:-1 gene... [more]
zgc:558888.188e-1629.75zgc:55888 [Source:ZFIN;Acc:ZDB-GENE-040426-834][more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMPRSS98.139e-1930.13transmembrane serine protease 9 [Source:NCBI gene;... [more]
TMPRSS98.162e-1930.13transmembrane serine protease 9 [Source:NCBI gene;... [more]
dkk21.297e-1732.05dickkopf WNT signaling pathway inhibitor 2 [Source... [more]
dkk21.496e-1732.05dickkopf WNT signaling pathway inhibitor 2 [Source... [more]
ENSXETT00000036430.11.732e-1735.48prostasin-like [Source:NCBI gene;Acc:101734975][more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Klkb11.014e-2035.81kallikrein B, plasma 1 [Source:MGI Symbol;Acc:MGI:... [more]
Tmprss93.548e-1832.69transmembrane protease, serine 9 [Source:MGI Symbo... [more]
Tmprss93.548e-1832.69transmembrane protease, serine 9 [Source:MGI Symbo... [more]
Tmprss133.177e-1733.33transmembrane protease, serine 13 [Source:MGI Symb... [more]
Tmprss25.885e-1731.29transmembrane protease, serine 2 [Source:MGI Symbo... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P26262|KLKB1_MOUSE7.095e-2035.81Plasma kallikrein OS=Mus musculus OX=10090 GN=Klkb... [more]
sp|P14272|KLKB1_RAT2.565e-1934.46Plasma kallikrein OS=Rattus norvegicus OX=10116 GN... [more]
sp|P54629|TRYU_DROER1.482e-1832.28Trypsin eta OS=Drosophila erecta OX=7220 GN=etaTry... [more]
sp|O15393|TMPS2_HUMAN2.381e-1836.73Transmembrane protease serine 2 OS=Homo sapiens OX... [more]
sp|P98073|ENTK_HUMAN2.500e-1832.48Enteropeptidase OS=Homo sapiens OX=9606 GN=TMPRSS1... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3S5CJI82.424e-4345.39Peptidase S1 domain-containing protein OS=Protopol... [more]
A0A183W1616.855e-3945.39Peptidase S1 domain-containing protein OS=Trichobi... [more]
A0A3P8LM667.006e-3945.39Peptidase S1 domain-containing protein OS=Trichobi... [more]
A0A183LRV22.789e-3844.74Peptidase S1 domain-containing protein OS=Schistos... [more]
A0A183QKR25.899e-3845.39Peptidase S1 domain-containing protein OS=Schistos... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmprss54.734e-1732.26transmembrane serine protease 5 [Source:ZFIN;Acc:Z... [more]
zmp:00000010884.978e-1732.90trypsin-like [Source:NCBI gene;Acc:103044589][more]
ENSAMXT00000049564.16.913e-1730.07coagulation factor X-like [Source:NCBI gene;Acc:10... [more]
ENSAMXT00000003105.28.753e-1730.07coagulation factor X-like [Source:NCBI gene;Acc:10... [more]
ENSAMXT00000036517.12.506e-1629.38pep primary_assembly:Astyanax_mexicanus-2.0:3:2187... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000001315.11.490e-1733.99pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-... [more]
tmprss3a3.873e-1529.01transmembrane serine protease 3a [Source:ZFIN;Acc:... [more]
ENSPMAT00000007252.11.203e-1434.21pep scaffold:Pmarinus_7.0:GL477828:77502:80240:-1 ... [more]
ENSPMAT00000006839.13.990e-1434.64pep scaffold:Pmarinus_7.0:GL478004:17964:21571:1 g... [more]
ENSPMAT00000006889.17.060e-1431.21pep scaffold:Pmarinus_7.0:GL476534:609000:610491:1... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO424203.652e-1931.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO434545.329e-1830.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO396236.952e-1830.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461031.008e-1730.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO389002.344e-1633.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmprss52.494e-1632.26transmembrane serine protease 5 [Source:NCBI gene;... [more]
ENSORLT00000009057.24.583e-1631.37transmembrane protease serine 4 [Source:NCBI gene;... [more]
ENSORLT00000034247.15.339e-1631.37transmembrane protease serine 4 [Source:NCBI gene;... [more]
ENSORLT00000042683.15.392e-1630.38pep primary_assembly:ASM223467v1:8:2747794:2749967... [more]
tmprss56.825e-1631.61transmembrane serine protease 5 [Source:NCBI gene;... [more]
back to top
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000072099.14.157e-11298.72SMESG000072099.1[more]
SMESG000072099.14.228e-11298.72SMESG000072099.1[more]
SMESG000072099.13.695e-11198.72SMESG000072099.1[more]
SMESG000012752.12.090e-4449.67SMESG000012752.1[more]
SMESG000012752.12.163e-4449.67SMESG000012752.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031603 ID=SMED30031603|Name=Peptidase S1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=476bp
AATTTTTAAACGCAGAAAAACTTGAATACGACATAGCATTGATTAAAGTG
GACAAGAAATTAGAATTTGGATATTATAAAACAAAAATAAGCATAAAAAT
GCTACCAAAAACGTTGGGTATGAATTGGCCGAAAACTGATCAGAACTGTA
TTTTTGTCGGATGGGGCTGCACGACTCCCCAAGGATTAATTAGTGAAAGA
GCCCAAACGGTAACTTTACCAATAATTGAGCAGAAGCGTTGTAGTGAAAC
TTATGTTGGAGTGTATGATAGTATTAATAGAAAGCATGAATTCTGTGCTG
GATATTATGACAGTGACGTTGGAATATGTACAGGTGACAGTGGAAGTGGT
TTGGTATGTAGTCACAATAACAAGTATTATCTAGCTGGGATTGCATCTGG
AACCTCTGGAACCAGACCAGGACGATATCCAGGAATATTTACAAGAGTAT
CATATTTCTCCAAATGGATTACATCA
back to top

protein sequence of SMED30031603-orf-1

>SMED30031603-orf-1 ID=SMED30031603-orf-1|Name=SMED30031603-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=158bp
FLNAEKLEYDIALIKVDKKLEFGYYKTKISIKMLPKTLGMNWPKTDQNCI
FVGWGCTTPQGLISERAQTVTLPIIEQKRCSETYVGVYDSINRKHEFCAG
YYDSDVGICTGDSGSGLVCSHNNKYYLAGIASGTSGTRPGRYPGIFTRVS
YFSKWITS
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR001254Trypsin_dom
IPR009003Peptidase_S1_PA
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0008233peptidase activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001254Serine proteases, trypsin domainSMARTSM00020trypsin_2coord: 1..156
e-value: 1.7E-6
score: 12.7
IPR001254Serine proteases, trypsin domainPFAMPF00089Trypsincoord: 3..156
e-value: 1.2E-28
score: 100.4
IPR001254Serine proteases, trypsin domainPROSITEPS50240TRYPSIN_DOMcoord: 1..158
score: 16.257
IPR001254Serine proteases, trypsin domainCDDcd00190Tryp_SPccoord: 3..156
e-value: 4.52736E-37
score: 125.081
NoneNo IPR availableGENE3DG3DSA:2.40.10.10coord: 2..158
e-value: 3.3E-36
score: 126.9
NoneNo IPR availablePANTHERPTHR24253FAMILY NOT NAMEDcoord: 8..157
IPR009003Peptidase S1, PA clanSUPERFAMILYSSF50494Trypsin-like serine proteasescoord: 4..158