Innexin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031582 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]) HSP 1 Score: 203.756 bits (517), Expect = 5.221e-60 Identity = 122/379 (32.19%), Postives = 211/379 (55.67%), Query Frame = 1 Query: 391 EDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLED-LFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDF 1524 +D DK ++ ++ I+ ++IVS KQY+ I C++P + ++Y +NYCWV T P + +R+I+YYQWVPFVL L+ + FY+P ++W+ +++ SG +++ L A A + R T+ +A +ED L +QR V +S +C +R + LY+ IK+LYL N + Q+ ++ +FL N +G+ IL+D+L+G++W + FPRV+ C ++ + + +HH QC L INM NEKI++FLWFW V F++ +S+ W+ ++F + R + D+++ + +FV +FL +DG+F + +IS +AGD++AT+++ LW +N KI F Sbjct: 19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFPLEYGD----RRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREV----------TDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFL----GTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDF-EVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWII-ISFLPGQHMKFIRKYLRATDLATDRQS-VKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQF 375
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]) HSP 1 Score: 203.756 bits (517), Expect = 5.221e-60 Identity = 122/379 (32.19%), Postives = 211/379 (55.67%), Query Frame = 1 Query: 391 EDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLED-LFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDF 1524 +D DK ++ ++ I+ ++IVS KQY+ I C++P + ++Y +NYCWV T P + +R+I+YYQWVPFVL L+ + FY+P ++W+ +++ SG +++ L A A + R T+ +A +ED L +QR V +S +C +R + LY+ IK+LYL N + Q+ ++ +FL N +G+ IL+D+L+G++W + FPRV+ C ++ + + +HH QC L INM NEKI++FLWFW V F++ +S+ W+ ++F + R + D+++ + +FV +FL +DG+F + +IS +AGD++AT+++ LW +N KI F Sbjct: 19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFPLEYGD----RRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREV----------TDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFL----GTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDF-EVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWII-ISFLPGQHMKFIRKYLRATDLATDRQS-VKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQF 375
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412]) HSP 1 Score: 205.297 bits (521), Expect = 8.598e-60 Identity = 125/387 (32.30%), Postives = 213/387 (55.04%), Query Frame = 1 Query: 358 TAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTK--FPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRM---TXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNK 1503 +AF+A +D DK ++ ++ IL +++VS KQY+ I C++P + +++Y +NYCWV T E +P+ I + +R+I YYQWVPF+L ++ +LFY+P ++W+ ++Y SG +L+GLV A A EI+ T+ +A+ ++D GH++ F L+ + CGR G + LYI IK+LY N + Q L+ + L G + L A+G+++LKD++ +W +FPRV+ C ++ + + + H QC L INM NEKI++FLWFW + +T+ + W+ M + R L A + +F FLR DG+F+L +IS +AG+L++++++ LW+ +N Sbjct: 69 SAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPRE----IYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDELTNIDRQGHSRSCFSNLQLGAN---CGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLL--GSNDL--AYGFSLLKDLMHAIEWEQTGMFPRVTLCDF-EVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNN 442
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412]) HSP 1 Score: 205.297 bits (521), Expect = 1.172e-59 Identity = 125/387 (32.30%), Postives = 213/387 (55.04%), Query Frame = 1 Query: 358 TAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTK--FPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRM---TXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNK 1503 +AF+A +D DK ++ ++ IL +++VS KQY+ I C++P + +++Y +NYCWV T E +P+ I + +R+I YYQWVPF+L ++ +LFY+P ++W+ ++Y SG +L+GLV A A EI+ T+ +A+ ++D GH++ F L+ + CGR G + LYI IK+LY N + Q L+ + L G + L A+G+++LKD++ +W +FPRV+ C ++ + + + H QC L INM NEKI++FLWFW + +T+ + W+ M + R L A + +F FLR DG+F+L +IS +AG+L++++++ LW+ +N Sbjct: 82 SAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPRE----IYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDELTNIDRQGHSRSCFSNLQLGAN---CGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLL--GSNDL--AYGFSLLKDLMHAIEWEQTGMFPRVTLCDF-EVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNN 455
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412]) HSP 1 Score: 204.912 bits (520), Expect = 4.693e-59 Identity = 125/387 (32.30%), Postives = 213/387 (55.04%), Query Frame = 1 Query: 358 TAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTK--FPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRM---TXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNK 1503 +AF+A +D DK ++ ++ IL +++VS KQY+ I C++P + +++Y +NYCWV T E +P+ I + +R+I YYQWVPF+L ++ +LFY+P ++W+ ++Y SG +L+GLV A A EI+ T+ +A+ ++D GH++ F L+ + CGR G + LYI IK+LY N + Q L+ + L G + L A+G+++LKD++ +W +FPRV+ C ++ + + + H QC L INM NEKI++FLWFW + +T+ + W+ M + R L A + +F FLR DG+F+L +IS +AG+L++++++ LW+ +N Sbjct: 128 SAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPRE----IYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDELTNIDRQGHSRSCFSNLQLGAN---CGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLL--GSNDL--AYGFSLLKDLMHAIEWEQTGMFPRVTLCDF-EVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNN 501
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860) HSP 1 Score: 82.4185 bits (202), Expect = 1.033e-16 Identity = 82/294 (27.89%), Postives = 123/294 (41.84%), Query Frame = 1 Query: 463 TKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETL----------PQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVV--SAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILK-DILSGKQWNDNL--LFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMT 1299 ++QYI I C + + GV + YCW++ T F E L P D + YYQWV FVL Q +LFY+PR +WK+ G L+ LV+ ++ +++ RK K L D F+ L F R + V + L N I QI + FL S +G +LK L + D + +FP+V+ C H C LP+N++NEKIY+FLWFW + + ++ IS+ +YR+ Sbjct: 44 SRQYIGDPIDCIVDEIPLGV-----MDTYCWIYST--FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKS----WEGGRLKMLVMDLNSPIVNDECKNDRK-------KILVDYFIGN--LNRHNFYAFR-------------------FFVCEALNFVNVIGQIYFVDFFLDGEFS----TYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL---IYRIA 291
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005) HSP 1 Score: 82.4185 bits (202), Expect = 1.033e-16 Identity = 82/294 (27.89%), Postives = 123/294 (41.84%), Query Frame = 1 Query: 463 TKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETL----------PQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVV--SAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILK-DILSGKQWNDNL--LFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMT 1299 ++QYI I C + + GV + YCW++ T F E L P D + YYQWV FVL Q +LFY+PR +WK+ G L+ LV+ ++ +++ RK K L D F+ L F R + V + L N I QI + FL S +G +LK L + D + +FP+V+ C H C LP+N++NEKIY+FLWFW + + ++ IS+ +YR+ Sbjct: 44 SRQYIGDPIDCIVDEIPLGV-----MDTYCWIYST--FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKS----WEGGRLKMLVMDLNSPIVNDECKNDRK-------KILVDYFIGN--LNRHNFYAFR-------------------FFVCEALNFVNVIGQIYFVDFFLDGEFS----TYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL---IYRIA 291
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314) HSP 1 Score: 82.4185 bits (202), Expect = 1.033e-16 Identity = 82/294 (27.89%), Postives = 123/294 (41.84%), Query Frame = 1 Query: 463 TKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETL----------PQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVV--SAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILK-DILSGKQWNDNL--LFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMT 1299 ++QYI I C + + GV + YCW++ T F E L P D + YYQWV FVL Q +LFY+PR +WK+ G L+ LV+ ++ +++ RK K L D F+ L F R + V + L N I QI + FL S +G +LK L + D + +FP+V+ C H C LP+N++NEKIY+FLWFW + + ++ IS+ +YR+ Sbjct: 44 SRQYIGDPIDCIVDEIPLGV-----MDTYCWIYST--FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKS----WEGGRLKMLVMDLNSPIVNDECKNDRK-------KILVDYFIGN--LNRHNFYAFR-------------------FFVCEALNFVNVIGQIYFVDFFLDGEFS----TYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL---IYRIA 291
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006) HSP 1 Score: 82.4185 bits (202), Expect = 1.033e-16 Identity = 82/294 (27.89%), Postives = 123/294 (41.84%), Query Frame = 1 Query: 463 TKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETL----------PQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVV--SAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILK-DILSGKQWNDNL--LFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMT 1299 ++QYI I C + + GV + YCW++ T F E L P D + YYQWV FVL Q +LFY+PR +WK+ G L+ LV+ ++ +++ RK K L D F+ L F R + V + L N I QI + FL S +G +LK L + D + +FP+V+ C H C LP+N++NEKIY+FLWFW + + ++ IS+ +YR+ Sbjct: 44 SRQYIGDPIDCIVDEIPLGV-----MDTYCWIYST--FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKS----WEGGRLKMLVMDLNSPIVNDECKNDRK-------KILVDYFIGN--LNRHNFYAFR-------------------FFVCEALNFVNVIGQIYFVDFFLDGEFS----TYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL---IYRIA 291
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0071037) HSP 1 Score: 79.337 bits (194), Expect = 1.240e-15 Identity = 67/271 (24.72%), Postives = 112/271 (41.33%), Query Frame = 1 Query: 469 QYITADISCYIPVVLSGVDLDKYVKNYCWVHGT--IPFYANETL------PQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQ-----NFLKYGVSKLNAAFGWTILKDILSGKQWNDNL-LFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFW 1239 QY+ ISC +++GV V +CW+H T +P + P +++ DA + YYQWV FVL Q + Y P+ +W L + GL ++ + + E +++ +L +L + V H + + +CC N I Q+ LM FL YG + + L D+ ++ + + +FPRV+ C H + C LP+N++NEK Y+F+WFW Sbjct: 46 QYVGQPISC----IVNGVP-PHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNITI--CTREEKEAKRDALLD--------YLIKHVKRHKLYAIRYWACEFLCC--------------------INIIVQMYLMNRFFDGEFLSYGTNIMK-------LSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEKTYVFIWFW 274
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1) HSP 1 Score: 201.06 bits (510), Expect = 1.739e-56 Identity = 125/389 (32.13%), Postives = 214/389 (55.01%), Query Frame = 1 Query: 358 TAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRV--LGHTK--FPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRM---TXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNK 1503 +AF+A +D DK ++ ++ IL +++VS KQY+ I C++P + +++Y +NYCWV T E +P+ I + +R+I YYQWVPF+L ++ +LFY+P ++W+ ++Y SG +L+GLV A A EI+ T+ +A+ ++D + GH++ F L+ + CGR G + LYI IK+LY N + Q L+ + L G + L A+G+++LKD++ +W +FPRV+ C ++ + + + H QC L INM NEKI++FLWFW + +T+ + W+ M + R L A + +F FLR DG+F+L +IS +AG+L++++++ LW+ +N Sbjct: 128 SAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPRE----IYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGAN---CGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLL--GSNDL--AYGFSLLKDLMHAIEWEQTGMFPRVTLCDF-EVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNN 503
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1) HSP 1 Score: 192.2 bits (487), Expect = 1.611e-54 Identity = 116/370 (31.35%), Postives = 204/370 (55.14%), Query Frame = 1 Query: 391 EDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLED-LFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIY 1497 +D DK ++ ++ I+ V +++VS KQY+ I C++P + +++Y +NYCWV T ++ +P E +R+I YYQWVPFVL L+ +LFY+P ++W+ + + SG ++ LV A + E R + +A +E+ L ++ +V+ + +L +LI C R +G LYI +K+LY N + QI L+ FL + +G +L D+++G++W ++ FPRV+ C ++ + + + H QC L INM NEKI++FLWFW + T+ S+ W+Y ++ +F+ ++L Y + +FV FLR DG+F+L +++ +AG+L ++ LW Y Sbjct: 21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTE-PMEQYTENYCWVQNTYFLPLHDYIPHNYAE----RENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQ-SGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLL----NLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFL----GNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDF-EVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2) HSP 1 Score: 179.104 bits (453), Expect = 2.332e-49 Identity = 116/373 (31.10%), Postives = 196/373 (52.55%), Query Frame = 1 Query: 391 EDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAF--GWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNK 1503 +DA D+ S++ + +L S++VS KQY+ + I C++P+ G ++Y ++YC++ T +P ++ A+ I YYQWVP VL +Q +FYLP IW ++ Y G D ++ A+ +Q E R + + ++ + D+ R + +F R G+ G LYI IKL+YL N Q I++ FL N F G+ D+ +G++W D+ +FPRV+ C S + + + + + QC L INM NEKIY+F+WFW V VL T I+ +YR++F R ++I+ L KD+K +I+ F L+ DG+ ++ I +AG ++ +I EL++ + + Sbjct: 21 DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKG-GWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAE----IGYYQWVPIVLAIQAFMFYLPSWIWSSL-YKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGDILDTRSKNEYGRFYCYR-------FGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLG------NETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFS-VRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGE 373
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23027|INX5_CAEEL (Innexin-5 OS=Caenorhabditis elegans OX=6239 GN=inx-5 PE=3 SV=2) HSP 1 Score: 166.777 bits (421), Expect = 1.830e-44 Identity = 104/375 (27.73%), Postives = 199/375 (53.07%), Query Frame = 1 Query: 394 DAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGT--IP-FYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLW--LYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLI-SQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYN 1500 D AD+ S+ ++ +L +++++ QY+ I C++P + +KY + YC++ GT +P +A+E A+ ++ YYQW+P VL LQ LFYLP +IW+T +N S + + +AS ++ + ++ K F +++ + PV ++ S++ G+ F +LY+++K+LYL N + Q ++ FL+ + +GW +D+++G++W +FPRV+ C S I +T + H QC + INML EK+Y+F WFW + V LT+ S+ W +Y + + + + +++ + + + FV++ L DG+FI ++ N+GDL + ++ E++ +Y Sbjct: 20 DIADRFSYQYTSTLLGFSAIMMAASQYVGRPIQCWVPAQFTRT-WEKYAETYCFIKGTYFLPGAFASEGEMSVTSPDDAVTATPQVGYYQWIPIVLVLQAFLFYLPSIIWRT--FNESCELKIKELAAVSEASRKIKSNMSDDQVKATKFGRYFF--KKLNFRNESPVFKETGSVVASGK----FLPALYLLVKILYLANIVLQFWILTYFLE----TKSWMWGWQTFQDLMAGREWETTGIFPRVTMCDFS-IMDLTSVHDHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVCSLAYWAVIYMLQSVGRNFIYSYLQQTPEFQTEQERGSFVPANFVDKCLTPDGVFISRLVQQNSGDLFTSIMLGEMFSLYR 380
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1) HSP 1 Score: 157.147 bits (396), Expect = 7.921e-41 Identity = 120/380 (31.58%), Postives = 204/380 (53.68%), Query Frame = 1 Query: 391 EDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQT---KDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFIS-LYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNL------ISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYN 1500 +D +D+ ++L + IL+ SV++S KQ+ I C P G ++Y +NYCW T ++ T + K+E D R+++YYQWVPF L LQ F P +WK N SG + +V AK ++N E+R++ IL + + L + + K V + ++ + +G FIS +Y+ K+LY N Q+ LM FL G ++ + +G+ +++DI+ G+ W + FPR + C ++ V + + QC L IN+ NEKI++ LWFW V +L + +S+ W + F K F+K+ L + + +++N +S+FV Q+L DG+F+L ++S +AG + ATD+V L+E Y+ Sbjct: 20 DDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPG-SWEQYAENYCWSQDT--YFVEPTQDVSLLKKEERYTPD--RQLSYYQWVPFFLLLQAAFFRAPSYLWK-YFSNHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSALRFQANMERKKVQV-HKTVTFLNFQYSSG--FISWIYLFTKVLYFLNVFAQLYLMNYFL--GTNR-HHWYGFGVVQDIVQGEPWERSGYFPRAAVCDF-EVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHLALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAYD 386
BLAST of Innexin vs. TrEMBL
Match: Q2L6M5 (Innexin OS=Dugesia japonica OX=6161 GN=inx10 PE=2 SV=1) HSP 1 Score: 618.231 bits (1593), Expect = 0.000e+0 Identity = 313/415 (75.42%), Postives = 365/415 (87.95%), Query Frame = 1 Query: 334 METFLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDK-KNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSKQTFV 1575 ME+ L+QF+AF+ KYVGIED ADKASFLFSV IL VCS+I+STKQY+T DISCYIP+V+SG D +K+++NYCWVHGTIPF +NE+LPQTK+EW+ A+ +RKINYYQWVPFVLGLQGVLFYLPRLIW+TIIYNLSGN LEGLVVSA+KA+NQVG+ RKETI Q+AK LEDLFLQRRVLGH KFPVLRQKMSL+CCGRRTG+F +SLY VIK+LYL NAI QI+LMQNFL+ G +KLN AFGWTIL DI+SGKQW +NLLFPR +FCFI DIS V KNH +AQC LPINMLNEKIYIFLWFWTVGVL LT+ISIPLWL+RMTFF KR+ F+K+FLKIK +Y+K K K L+S FVE+FLRHDGIFILHIISLNAGDLIA D+V+ELW+IY KYY++ DF K IS +EK+ Q+FV Sbjct: 1 MESLLTQFSAFKVEKYVGIEDGADKASFLFSVAILAVCSIIISTKQYVTTDISCYIPIVVSGSDFEKFIRNYCWVHGTIPFRSNESLPQTKEEWMTAEYTRKINYYQWVPFVLGLQGVLFYLPRLIWRTIIYNLSGNHLEGLVVSAQKATNQVGDNRKETIEQIAKSLEDLFLQRRVLGHKKFPVLRQKMSLVCCGRRTGIFLVSLYFVIKILYLINAIGQILLMQNFLRLGTTKLNVAFGWTILHDIISGKQWTENLLFPRTTFCFIGDISLVAVKNHFVAQCTLPINMLNEKIYIFLWFWTVGVLILTLISIPLWLWRMTFFSKRQKFVKKFLKIKCSYSKGKHKELMSHFVERFLRHDGIFILHIISLNAGDLIAADVVTELWQIYTKYYVERDFSKNVISIIDEKTNQSFV 415
BLAST of Innexin vs. TrEMBL
Match: A0A5J4NXS3 (Innexin OS=Paragonimus westermani OX=34504 GN=inx PE=3 SV=1) HSP 1 Score: 355.14 bits (910), Expect = 7.625e-114 Identity = 179/389 (46.02%), Postives = 265/389 (68.12%), Query Frame = 1 Query: 343 FLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKM----SLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIY 1497 F+ Y+G+ED ADK SFL+SV++L++C+ +V+ KQY+ + ISCYIP V SG D DK+++N+CWVHGTIPF ++E +PQT DEW D +INYYQWVPF+LGLQ +LFY+PR+IW+ I N +G D+E LV+ A +ASN + RK+ + VA L+++ Q R K ++ ++ L+ +R G + Y ++K+ YL+N++ Q+ LM+ FL + S N FG + +++G+ W +FPR+SFC+++D+ + N ++AQC LP+NMLNEK+YIFLW+WTV V T +SIPLW+ R+T F+ R F+K+FL+I + K K+L+ QF EQFLRHDGIF+L +IS+NAGD+I +++VSELW Y Sbjct: 6 FIDFLKKLHVPDYIGVEDFADKLSFLYSVLVLMLCTAVVTVKQYLMSAISCYIPTVPSGTDFDKFLENFCWVHGTIPFLSDEPMPQTLDEWAYFDQKYRINYYQWVPFMLGLQCMLFYIPRVIWQVICCNRAGTDIEHLVLVAYQASNSKPDERKQLVSHVASSLKEMLYQHREYRDGKLVEVKNRVFDACGLLVVSKRLGTWLAFTYFIVKVCYLSNSVGQLYLMKRFLGFNASLTN--FGMELAHFMMTGRNWEQTRIFPRISFCYMADLRQLGSTNRYVAQCVLPVNMLNEKLYIFLWYWTVMVSICTALSIPLWMLRLTIFKNRLHFVKKFLRINEQFHKTDKSLLKQFTEQFLRHDGIFLLRMISMNAGDVITSEVVSELWRNY 392
BLAST of Innexin vs. TrEMBL
Match: H2KV19 (Innexin OS=Clonorchis sinensis OX=79923 GN=inx PE=3 SV=1) HSP 1 Score: 354.369 bits (908), Expect = 7.901e-114 Identity = 184/387 (47.55%), Postives = 257/387 (66.41%), Query Frame = 1 Query: 343 FLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKM----SLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWE 1491 FL Y+G+ED ADK SFL+SV++L++C+ IV+ KQY+ + I+CYIP V SG D DK+++N+CWVHGTIP +NE +PQT DEW D +INYYQWVPF+LGLQ +LFY+PR++W+ I N +G D+E LVV A +ASN R + + V L+ + Q R H + ++++ L+ +R G + Y VIKLLYLTN++ Q+ LMQ FL + + N FG + +LSG+ W +FPR+SFC+ +D+ + N ++AQC LP+NMLNEK+YIFLW+WT V LT SIPLWL R+TF + R FIK+FL+I + + K L+ F E FLRHDGIFIL +IS+NAGD+I +++VSELW+ Sbjct: 6 FLDFLNKLHVPDYIGVEDFADKLSFLYSVLVLMLCTTIVTVKQYLMSAIACYIPTVPSGSDFDKFLENFCWVHGTIPLLSNELIPQTMDEWAYFDDKYRINYYQWVPFMLGLQCMLFYIPRIVWQLICCNRTGTDIEHLVVVAHQASNASPTDRSKLVSHVTASLKGMLYQHREYRHGRVLEAKKRLFDACGLLVVSKRLGTWLAFTYFVIKLLYLTNSVGQLYLMQRFLGFNATLTN--FGAKLADYMLSGRNWEQTRIFPRISFCYFADLRQLGSTNRYVAQCVLPVNMLNEKLYIFLWYWTAMVAILTAFSIPLWLMRLTFAKSRVRFIKKFLRINEQFHRSDKQLVKDFTENFLRHDGIFILRMISMNAGDVITSEVVSELWK 390
BLAST of Innexin vs. TrEMBL
Match: A0A4S2M067 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1) HSP 1 Score: 352.829 bits (904), Expect = 3.082e-113 Identity = 182/387 (47.03%), Postives = 257/387 (66.41%), Query Frame = 1 Query: 343 FLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKM----SLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWE 1491 F+ Y+G+ED ADK SFL+SV++L++C+ IV+ KQY+ + I+CYIP V SG D DK+++N+CWVHGTIP +NE +PQT DEW D +INYYQWVPF+LGLQ +LFY+PR++W+ I N +G D+E LVV A +ASN R + + V L+ + Q R H + ++++ L+ +R G + Y VIKLLYLTN++ Q+ LMQ FL + + N FG + +L+G+ W +FPR+SFC+ +D+ + N ++AQC LP+NMLNEK+YIFLW+WT V LT SIPLWL R+TF + R FIK+FL+I + + K L+ F E FLRHDGIFIL +IS+NAGD+I +++VSELW+ Sbjct: 6 FIDFLNKLHVPDYIGVEDFADKLSFLYSVLVLMLCTTIVTVKQYLMSAIACYIPTVPSGSDFDKFLENFCWVHGTIPLLSNELIPQTMDEWAYFDDRYRINYYQWVPFMLGLQCMLFYIPRIVWQLICCNRTGTDIEHLVVVAHQASNATTTDRSKLVSHVTASLKGMLYQHREYRHGRVLEAKKRLFDACGLLVVSKRLGTWLAFTYFVIKLLYLTNSVGQLYLMQKFLGFNATLTN--FGAKLADYMLTGRNWEQTRIFPRISFCYFADLRQLGSTNRYVAQCVLPVNMLNEKLYIFLWYWTAMVAILTAFSIPLWLMRLTFAKSRVRFIKKFLRINEQFHRSDKQLVKDFTENFLRHDGIFILRMISMNAGDVITSEVVSELWK 390
BLAST of Innexin vs. TrEMBL
Match: Q2L6M6 (Innexin OS=Dugesia japonica OX=6161 GN=inx9 PE=2 SV=1) HSP 1 Score: 352.058 bits (902), Expect = 7.531e-113 Identity = 183/431 (42.46%), Postives = 270/431 (62.65%), Query Frame = 1 Query: 337 ETFLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLIC--C--GRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDF-----------------RKKYISSSNEKSKQ 1566 + FLS F+ YVG+ED ADK +FLFSV+IL++ ++V+ K Y ++CYI SG + D Y++NYCWVHGTI E +PQT +W I D +++I YYQWVPF+LGLQ ++FY+PR+IW+ I YN G +LE L + A AS+ RK+ I ++ + +ED+ Q R K +R+ + +C C + G + + YI++K +Y N I Q+ LM+ FL + S ++FG+TIL +I GK+W+ +FPRV++C+I +I + N ++ QCALPINMLNEKIY+FLWFW V +T ISIP+W +R+ +R FIK+FL + AY + K LI+ F+ +FLRHDG+F++ +I +NAGD++ DIV+ LWEIY + Y +DF R + ISSS+E K+ Sbjct: 4 QEFLSLVGQFKLTSYVGVEDFADKLNFLFSVVILIISMMVVTVKSYFFKPLACYIATTPSGSNFDNYLENYCWVHGTISILPGENIPQTDADWAIVDQTKRITYYQWVPFILGLQCIMFYVPRVIWQLICYNKVGTNLESLAIDADAASHSPPSERKDKIERIVRTIEDMLFQHRDYRQGKMADMRRNIYKMCNFCVFSKHMGTWLVLSYILMKFMYGINVIGQLFLMKKFLGFNSSM--SSFGYTILSNIADGKEWHQTGIFPRVTYCYIGEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFLVGIITAISIPMWFFRIAILSRRSSFIKKFLMMHQAYNRSDKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLWEIYKENYKNMDFLNFSAYPKPMDMTTGLRRNQNISSSDESIKK 432
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000081749.1 (SMESG000081749.1) HSP 1 Score: 779.63 bits (2012), Expect = 0.000e+0 Identity = 414/414 (100.00%), Postives = 414/414 (100.00%), Query Frame = 1 Query: 334 METFLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSKQTFV 1575 METFLSQFTAFQAGKYVGIEDAADKASFLFSVIILVVCSVIVSTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTFFRKRKDFIKRFLKIKSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSKQTFV Sbjct: 1 METFLSQFTAFQAGKYVGIEDAADKASFLFSVIILVVCSVIVSTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTFFRKRKDFIKRFLKIKSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSKQTFV 414
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000081749.1 (SMESG000081749.1) HSP 1 Score: 713.375 bits (1840), Expect = 0.000e+0 Identity = 373/414 (90.10%), Postives = 393/414 (94.93%), Query Frame = 1 Query: 334 METFLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSKQTFV 1575 ME+ + +F+ F KYVG+ED ADKASFLFSV+ILVVC+VIVSTKQYI +I+CYIP++ +G L+ Y++NYCW HGTIPF NETLPQ + +W+ AD R++NYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTFFRKRKDFIKRFLKIKSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSKQTFV Sbjct: 1 MESLIGEFSNFNVEKYVGVEDGADKASFLFSVVILVVCTVIVSTKQYIFGEIACYIPILNTGEKLEDYIQNYCWAHGTIPFRENETLPQNRKDWMQADFDRRLNYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTFFRKRKDFIKRFLKIKSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSKQTFV 414
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000061679.1 (SMESG000061679.1) HSP 1 Score: 364.77 bits (935), Expect = 1.542e-121 Identity = 192/403 (47.64%), Postives = 273/403 (67.74%), Query Frame = 1 Query: 334 METFLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDL-FLQRRVLGHTKFPVLRQ---KMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRK 1530 + F+ T ++ +VG+ED ADK SF S IL++ +++++ K Y+ I+CYIP+ SG D D ++K+YCWVHGTIP N LP + W D +INYYQWVPFVL LQG+LFYLPR+IW+ I YNLSG DLEGLV A ASNQ G+ + ET+ Q+A LE+L F R++ H+K P++ + S +C +R+G + Y+ IK+LY+ NA Q+ LMQ FL +G +FG+ +LK+IL G++WND ++FPRV++C++ +I V KN+++AQC LPINMLNEKIYIFLWFWTV V+F T IS+ W+YR+T + F+K+FL+I+ YT + +++ F FLR DG+FIL + S+NAGDLI DIV+ LW IY + + + +F K Sbjct: 3 LSEFIDYATKYKWADFVGMEDFADKLSFSISTSILLLLTLVITVKSYLLTSIACYIPIHPSGKDFDDFLKSYCWVHGTIPIKGN--LPPDIESWEKMDEFNRINYYQWVPFVLALQGILFYLPRIIWQMITYNLSGTDLEGLVEMANSASNQTGKAKSETVDQIAMNLENLLFSHRKINLHSK-PIMSKLSTAKSWLCSDKRSGRQLAAQYMFIKVLYVINAFGQLFLMQYFLDFGHK--GTSFGYVVLKNILEGREWNDTMIFPRVTYCYLKNIQHVAIKNNYLAQCVLPINMLNEKIYIFLWFWTVIVVFFTFISLFQWIYRLTQSSSQVHFLKKFLRIREQYTDEDCSVLKSFFRGFLRKDGVFILRMFSINAGDLITADIVTGLWNIYKEKHKEENFSK 400
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000080788.1 (SMESG000080788.1) HSP 1 Score: 355.91 bits (912), Expect = 6.060e-118 Identity = 185/402 (46.02%), Postives = 265/402 (65.92%), Query Frame = 1 Query: 337 ETFLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLIC--C--GRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRK 1530 E FL+ F+ YVGIED ADK SFLFSV +L++ ++V+ K Y+ ++CY G + + Y++NYCWVHGTI F E +PQ +W AD +R+INYYQWVPF+LGLQ +FY+P++IW+ I YN SG +LE +V A A+N RK+ I ++A+ +ED+ Q R F LR+K+ C C + G + I YI+IK LY N I Q+ +M+ FL G + ++FG+T+L +++SGK+W+ +FPRV++C++ +I V N ++AQCALP+NMLNEKIY+FLWFW V V +T ISIPLW YRM F +R FIKRFL + Y + K +I+ F+E+FLRHDG+F++ ++ +NAGD+I DIV+ L EIY + Y +DFR Sbjct: 4 EEFLNLIGQFKISTYVGIEDFADKLSFLFSVTLLILSMMVVTIKSYLFKPLACYTATAPGGSNFENYLENYCWVHGTITFLPGEDIPQNDVDWARADDTRRINYYQWVPFILGLQCFMFYIPKIIWQIICYNKSGTNLESIVNDANAANNTPPVERKDKIERIARTIEDMLFQHRDYRQGNFAKLRRKIYNTCNFCVFSKHMGTWLILSYILIKFLYGLNVIGQLFIMKKFL--GFNNSTSSFGYTVLSNMISGKEWHQTGIFPRVTYCYVRNIKHVGVANKYVAQCALPVNMLNEKIYVFLWFWMVLVGIVTAISIPLWFYRMAFLSRRSKFIKRFLMMHQNYERSDKPMINNFIEEFLRHDGVFLVRMLFINAGDIITADIVNRLLEIYKENYKHLDFRN 403
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1) HSP 1 Score: 310.457 bits (794), Expect = 3.840e-100 Identity = 182/417 (43.65%), Postives = 258/417 (61.87%), Query Frame = 1 Query: 343 FLSQFTAFQAGKYVGIEDAADKASFLFXXXXXXXXXXXXXTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKM----SLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLN-AAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHK---NHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTXXXXXXXXXXXXXXXXSAYTKDKKN--LISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDFRKKYISSSNEKSK 1563 FL + Q VG+ED D+ +F FSVI+L+VC +IV+ KQY+ ISCY+P + G +L YV+N CWV GTI P T +EW + K+ YYQWVPF+LGLQ ++FY+P+L+W+ I YN +G D++ LVVSA +A + E R + + ++K LE L Q R K R+K+ + C +R G + +S Y+++KL Y+ N Q+I+MQ FL G S N FG + +I SG W L+FPRVS+CF+ VTH N +AQC LP+NMLNE+IY FLW W + VL LTI+SIP+W+ R+ + R+ FI++FL I TKD+K L+++F QFLRHDGIF+L +ISLNAGD+I ++IV +LW IY Y+ +F ++KS+ Sbjct: 6 FLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLE-KHKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQHRDHRSGKLAKFRRKIHNSVGFLMCSKRIGTWLVSSYLLLKLSYVANGFIQLIIMQKFL--GFSDFNLLTFGIEVGNNIWSGTDWKTTLIFPRVSYCFVK----VTHLGVINSMVAQCVLPVNMLNERIYFFLWCWILIVLSLTILSIPIWILRILCIKYRRHFIRQFLIISEEITKDQKENYLLAKFESQFLRHDGIFLLKMISLNAGDIITSEIVCQLWNIYKTNYVNRNFLNDGSDEDDDKSR 415 The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031582 ID=SMED30031582|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1641bpback to top protein sequence of SMED30031582-orf-1 >SMED30031582-orf-1 ID=SMED30031582-orf-1|Name=SMED30031582-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=415bp METFLSQFTAFQAGKYVGIEDAADKASFLFSVIILVVCSVIVSTKQYITAback to top Aliases
The feature 'Innexin' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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