RING-type domain-containing protein

Overview
NameRING-type domain-containing protein
Smed IDSMED30031551
Length (bp)1885
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RING-type domain-containing protein (SMED30031551) t-SNE clustered cells

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30031551) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RING-type domain-containing protein (SMED30031551) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30031551) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30031551

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30031551SMESG000076269.1 SmedASXL_017037SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30031551SMESG000076269.1 SmedASXL_017037SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
muscle cellSMED30031551SMESG000076269.1 dd_Smed_v4_9026_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30031551SMESG000076269.1 dd_Smed_v4_9026_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 58.151 bits (139), Expect = 4.581e-8
Identity = 35/130 (26.92%), Postives = 59/130 (45.38%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E    ++G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESHQYVVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 57.7658 bits (138), Expect = 4.793e-8
Identity = 35/130 (26.92%), Postives = 59/130 (45.38%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E    ++G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESHQYVVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 53.1434 bits (126), Expect = 2.150e-7
Identity = 26/90 (28.89%), Postives = 45/90 (50.00%), Query Frame = 2 
Query:  131 WTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E    ++G+ I + L+
Sbjct:    7 WDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESHQYVVGDTITMQLM 95
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: CG12099 (gene:FBgn0035232 transcript:FBtr0072829)

HSP 1 Score: 51.2174 bits (121), Expect = 2.579e-6
Identity = 25/92 (27.17%), Postives = 42/92 (45.65%), Query Frame = 2 
Query:  131 WTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVK 406
            W+ + +I   T +   C IC    + A++ RCGH +C  C+L    ++      CP+C D  I    LK     + +   +GE I   L+ +
Sbjct:  196 WSYIEQINIQTTEELQCPICLYPPVAAKLTRCGHAYCWPCLLHYLSLSDKTWRKCPICYDA-IHAGDLKSCTIEQLRDLQVGEKITFQLMRR 286
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: CG12099 (gene:FBgn0035232 transcript:FBtr0072828)

HSP 1 Score: 51.2174 bits (121), Expect = 2.579e-6
Identity = 25/92 (27.17%), Postives = 42/92 (45.65%), Query Frame = 2 
Query:  131 WTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVK 406
            W+ + +I   T +   C IC    + A++ RCGH +C  C+L    ++      CP+C D  I    LK     + +   +GE I   L+ +
Sbjct:  196 WSYIEQINIQTTEELQCPICLYPPVAAKLTRCGHAYCWPCLLHYLSLSDKTWRKCPICYDA-IHAGDLKSCTIEQLRDLQVGEKITFQLMRR 286
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf10 (ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-2969])

HSP 1 Score: 58.151 bits (139), Expect = 2.917e-8
Identity = 33/131 (25.19%), Postives = 62/131 (47.33%), Query Frame = 2 
Query:   20 KYKMDNKINHRLAFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            K+   +K  ++  F+Q  C   V +   +  +  D      W  V ++  ++++   C IC    + A M RCGHI+C  C+L    +++ + + CP+C +   S + LK V   E +  + G  I + L+
Sbjct:  165 KWGHKHKPFNKELFLQANCQFVVSDDQDYQAHFTDPDTLVDWDCVQQVRIYSHEVPSCPICLYPPVAAHMTRCGHIYCWPCMLHYLSLSEKSWSKCPICYEAVHSAD-LKSVVAMETRQYVSGNSITMCLM 294
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: zgc:66440 (zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640])

HSP 1 Score: 50.0618 bits (118), Expect = 3.563e-6
Identity = 25/67 (37.31%), Postives = 40/67 (59.70%), Query Frame = 2 
Query:  119 HDFSWTSVSK-IICFTNDSKVCSICFDKII-LARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDV 313
             + S  +VS+ ++C   +S VCSIC  +++    +D+CGH FC SC+   F V K+    CP+C+ V
Sbjct:   86 QEASARTVSELVVCHEEESTVCSICMGEMVEKTTLDKCGHAFCRSCLEQAFQVKKA----CPVCRLV 148
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: zgc:66440 (zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640])

HSP 1 Score: 50.0618 bits (118), Expect = 3.563e-6
Identity = 25/67 (37.31%), Postives = 40/67 (59.70%), Query Frame = 2 
Query:  119 HDFSWTSVSK-IICFTNDSKVCSICFDKII-LARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDV 313
             + S  +VS+ ++C   +S VCSIC  +++    +D+CGH FC SC+   F V K+    CP+C+ V
Sbjct:   86 QEASARTVSELVVCHEEESTVCSICMGEMVEKTTLDKCGHAFCRSCLEQAFQVKKA----CPVCRLV 148
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: zgc:66440 (zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640])

HSP 1 Score: 50.0618 bits (118), Expect = 5.174e-6
Identity = 25/67 (37.31%), Postives = 40/67 (59.70%), Query Frame = 2 
Query:  119 HDFSWTSVSK-IICFTNDSKVCSICFDKII-LARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDV 313
             + S  +VS+ ++C   +S VCSIC  +++    +D+CGH FC SC+   F V K+    CP+C+ V
Sbjct:  156 QEASARTVSELVVCHEEESTVCSICMGEMVEKTTLDKCGHAFCRSCLEQAFQVKKA----CPVCRLV 218
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: zgc:66440 (zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640])

HSP 1 Score: 49.6766 bits (117), Expect = 6.469e-6
Identity = 22/56 (39.29%), Postives = 34/56 (60.71%), Query Frame = 2 
Query:  149 IICFTNDSKVCSICFDKII-LARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDV 313
            ++C   +S VCSIC  +++    +D+CGH FC SC+   F V K+    CP+C+ V
Sbjct:  191 VVCHEEESTVCSICMGEMVEKTTLDKCGHAFCRSCLEQAFQVKKA----CPVCRLV 242
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: egfl7 (EGF like domain multiple 7 [Source:Xenbase;Acc:XB-GENE-491413])

HSP 1 Score: 64.3142 bits (155), Expect = 3.969e-10
Identity = 38/131 (29.01%), Postives = 66/131 (50.38%), Query Frame = 2 
Query:   20 KYKMDNKINHRLAFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            ++K  NK  ++  F+Q  C   V +   +  +  D     SW  V ++  F+++   C IC    + A++ RCGHIFC +CIL    +++ + + CP+C    I  + LK V   E  L  +G+ I + L+
Sbjct:  148 RHKWGNKPFNKELFLQANCQFVVSDDNDYSVHFADPDTLVSWDFVEQVRIFSHEVPSCPICLYPPVAAKITRCGHIFCWACILHYLSLSEKDWSRCPICYSSVIKKD-LKSVVTTETHLYSVGDKITMQLM 277
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: egfl7 (EGF like domain multiple 7 [Source:Xenbase;Acc:XB-GENE-491413])

HSP 1 Score: 64.3142 bits (155), Expect = 4.032e-10
Identity = 38/131 (29.01%), Postives = 66/131 (50.38%), Query Frame = 2 
Query:   20 KYKMDNKINHRLAFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            ++K  NK  ++  F+Q  C   V +   +  +  D     SW  V ++  F+++   C IC    + A++ RCGHIFC +CIL    +++ + + CP+C    I  + LK V   E  L  +G+ I + L+
Sbjct:  148 RHKWGNKPFNKELFLQANCQFVVSDDNDYSVHFADPDTLVSWDFVEQVRIFSHEVPSCPICLYPPVAAKITRCGHIFCWACILHYLSLSEKDWSRCPICYSSVIKKD-LKSVVTTETHLYSVGDKITMQLM 277
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 58.151 bits (139), Expect = 2.347e-8
Identity = 35/134 (26.12%), Postives = 60/134 (44.78%), Query Frame = 2 
Query:   23 YKMDNKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            +   NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E +   +G+ I + L+
Sbjct:  128 WGKRNKWGHKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESRQYAVGDTITMQLM 260
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 58.151 bits (139), Expect = 2.802e-8
Identity = 35/130 (26.92%), Postives = 59/130 (45.38%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E +   +G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESRQYAVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 58.151 bits (139), Expect = 2.852e-8
Identity = 35/130 (26.92%), Postives = 59/130 (45.38%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E +   +G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESRQYAVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 58.151 bits (139), Expect = 2.903e-8
Identity = 35/130 (26.92%), Postives = 59/130 (45.38%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E +   +G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESRQYAVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q32NQ8|RNF10_XENLA (RING finger protein 10 OS=Xenopus laevis OX=8355 GN=rnf10 PE=2 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 1.027e-8
Identity = 38/131 (29.01%), Postives = 65/131 (49.62%), Query Frame = 2 
Query:   20 KYKMDNKINHRLAFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            ++K  NK  ++  F+Q  C   V +   +  +  D     SW  V ++  F+++   C IC    + A++ RCGHIFC  CIL    +++ + + CP+C    I  + LK V   E  L  +G+ I + L+
Sbjct:  149 RHKWANKPFNKELFLQANCQFVVSDVNDYSVHFTDPDTLVSWDFVEQVRIFSHEVASCPICLYPPVAAKITRCGHIFCWPCILHYLSLSEKDWSRCPICYSSIIKKD-LKSVVATETHLYSVGDKITMQLM 278
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5XI59|RNF10_RAT (RING finger protein 10 OS=Rattus norvegicus OX=10116 GN=Rnf10 PE=2 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 2.786e-8
Identity = 36/130 (27.69%), Postives = 60/130 (46.15%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  N  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E +  ++G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYTANFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSERTWSKCPICYS-SVHKKDLKSVVATESRQYVVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q08E13|RNF10_BOVIN (RING finger protein 10 OS=Bos taurus OX=9913 GN=RNF10 PE=2 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 1.744e-7
Identity = 35/130 (26.92%), Postives = 60/130 (46.15%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E +  ++G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYTVHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESRQYVVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3UIW5|RNF10_MOUSE (RING finger protein 10 OS=Mus musculus OX=10090 GN=Rnf10 PE=2 SV=2)

HSP 1 Score: 58.151 bits (139), Expect = 1.995e-7
Identity = 35/130 (26.92%), Postives = 59/130 (45.38%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E +   +G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESRQYAVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8N5U6|RNF10_HUMAN (RING finger protein 10 OS=Homo sapiens OX=9606 GN=RNF10 PE=1 SV=2)

HSP 1 Score: 58.151 bits (139), Expect = 2.200e-7
Identity = 35/130 (26.92%), Postives = 59/130 (45.38%), Query Frame = 2 
Query:   35 NKINHRL----AFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            NK  H+      F+Q  C   V E   +  +  D     +W  V ++   +++   C IC      A++ RCGHIFC +CIL    +++   + CP+C    +    LK V   E    ++G+ I + L+
Sbjct:  169 NKWGHKPFNKELFLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYS-SVHKKDLKSVVATESHQYVVGDTITMQLM 297
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A0R3WNE4 (RING-type domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS2271 PE=4 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.146e-9
Identity = 70/324 (21.60%), Postives = 143/324 (44.14%), Query Frame = 2 
Query:  131 WTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDV-NKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSYKDYNLPKLENSISKFLS-IVTEKDFRSQQDIIDDLNXXXXXXXXXXXXXXFPRXXXXXXXXXXXXXXXHFQDEIKVINKNEIDENCEIFEDNFNLIEYKNMKEKFELFYQAEGYRFVFLDQLNQKQILDKSQHTWKVVPVQIKSTIREIREEFVDNEFLMRTK-LSHLFRGVKVTIVTIDLPNALLEPIT---GGNLRILRSHQEQIYKARKEDL 1084
            W+ V  + C+  +  VC IC +  IL RM  CGH++C  C+       N ++   C +C  V++  N L+RV      +P +G+ ++L L+ + ++++ P  A  +    + +  +  N  S+FLS +V  K    Q+DI+  ++     +K     ++    + E+ L+  +   K       V  K  ++E      D  + +      E +  +YQ      ++L  +N + +++        +P +IK  + E+    + +    R + L HL  G    ++ I   N ++   T     ++  +R H+ +  +AR+  L
Sbjct:  113 WSDVLVVGCYQTEESVCPICLEAPILPRMGPCGHVYCYLCVSCYISFENDTSSKQCAVC-GVQLRTNDLRRVRLFSSHVPNVGDTVRLDLMRRHKRSIFPMVASEVQGRLEGS-GREANPASRFLSRLVVAK----QEDIVGLVDTDIATMKAFLAEDQLEEADEERFLIAKRILRK------LVAEKRSMEEATVFTRDEVSFVSNDTTAEDYFFYYQEVSGHDIYLHSINWRCLVE--DFGVSNLPQEIKGKVVEVETYTMSSALRSRYRHLRHLPLGRTFHLIEIQFENPIISAETLLLVSDVLTMRQHRREQKEARERSL 422
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A0K2TF82 (CG12099 CG12099PBlike [Tribolium castaneum] (Fragment) OS=Lepeophtheirus salmonis OX=72036 PE=4 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.580e-9
Identity = 41/136 (30.15%), Postives = 65/136 (47.79%), Query Frame = 2 
Query:   59 FIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSY 454
            ++Q  C   V     +  +I+D      W ++ ++   TND   C IC  +  +A+M RCGHI+C  CIL    ++  N   CP+C D  +    LK V         IG+ I+L+L+   ++N    FA+  T Y
Sbjct:   45 YLQANCQFLVKNNRDYSEHINDPDLPLDWEAIERVTLRTNDHPSCPICLYQPKVAKMTRCGHIYCWQCILHYLALSDDNWRKCPIC-DESVYKEDLKSVVTEPFSEHTIGDEIELNLM---RRNRTSMFAYLTTKY 176
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A0K2TF84 (CG12099 CG12099PBlike [Tribolium castaneum] OS=Lepeophtheirus salmonis OX=72036 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 2.328e-9
Identity = 41/136 (30.15%), Postives = 65/136 (47.79%), Query Frame = 2 
Query:   59 FIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSY 454
            ++Q  C   V     +  +I+D      W ++ ++   TND   C IC  +  +A+M RCGHI+C  CIL    ++  N   CP+C D  +    LK V         IG+ I+L+L+   ++N    FA+  T Y
Sbjct:  159 YLQANCQFLVKNNRDYSEHINDPDLPLDWEAIERVTLRTNDHPSCPICLYQPKVAKMTRCGHIYCWQCILHYLALSDDNWRKCPIC-DESVYKEDLKSVVTEPFSEHTIGDEIELNLM---RRNRTSMFAYLTTKY 290
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: E9H0B1 (RING-type domain-containing protein OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_306980 PE=4 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 3.674e-9
Identity = 36/128 (28.12%), Postives = 64/128 (50.00%), Query Frame = 2 
Query:   59 FIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPR 430
            ++Q  C   V     +   + D      W S+ +I  + ++   C IC    + A+M RCGHI+C  CIL    ++     PCP+C DV + I  LK V   EQ+   +G+ +++ L+ + + ++ P+
Sbjct:  166 YLQANCQFVVKADGDYTVYLADPDLLVPWESIEQIRIWGSEVGSCPICLHPPVAAKMTRCGHIYCWPCILHFLALSDKPSRPCPIC-DVSVRIQDLKSVVALEQRNLKVGDALEMRLMKRDRHSLQPQ 292
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A210PUY3 (RING finger protein 10 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT16827 PE=4 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 3.883e-9
Identity = 46/158 (29.11%), Postives = 74/158 (46.84%), Query Frame = 2 
Query:   59 FIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDV--EISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSYKDYNLPKL--ENSISKFLSI 508
            F+Q  C   V +K  +  + H+      W SV  I   ++++  C IC    + A+M RCGHI+C +CIL    + +     CP+C +   +  + S++  E H+ K   +GE I L L+ + + NV             Y LPK    N + KF S+
Sbjct:  137 FLQANCQFVVDQKGDYTIHNHNPDTLVDWDSVELIRVQSSETSSCPICLQAPVAAKMTRCGHIYCWACILHYLALGEKTWRKCPICYESIHDKDLRSVESKEVHQYK---VGETITLQLMKRQKGNV-------------YALPKSCEANKLGKFFSV 278
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf10 (ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-2969])

HSP 1 Score: 60.8474 bits (146), Expect = 2.891e-9
Identity = 34/131 (25.95%), Postives = 64/131 (48.85%), Query Frame = 2 
Query:   20 KYKMDNKINHRLAFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            K+   +K  ++  F+Q  C   V +   +  +  D     SW SV ++  ++++   C IC    + A + RCGHI+C  C+L    +++ + + CP+C +   S + LK V   E    + G+ I + L+
Sbjct:  169 KWGHKHKPFNKELFLQANCQFVVIDDQDYQAHFTDPDTLVSWDSVQQVRIYSHEVPTCPICLYPPVAAHITRCGHIYCWPCMLHYLSLSEKSWSKCPICYEAVHSAD-LKSVVAMETHQYVPGDVITMRLM 298
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Match: MAG2 (Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1 [Source:SGD;Acc:S000004419])

HSP 1 Score: 46.9802 bits (110), Expect = 8.176e-6
Identity = 30/103 (29.13%), Postives = 47/103 (45.63%), Query Frame = 2 
Query:  179 CSICF-DKIILARMDRCGHIFCLSCILSVFDV------------NKSNHAPCPMCKDVEISINSLKRVEFHE-------QKLPIIGEPIKLSLLVKGQQNVCP 427
            CSIC  ++ +  RM  CGHIFCLSC+L+ F +             K  +  CP+C  + I    +K V + +        + P  G  + L L+ K   ++ P
Sbjct:  195 CSICLSEEPVAPRMVTCGHIFCLSCLLNFFSIEETVKNKETGYSKKKKYKECPLCGSI-IGPKRVKPVLYEDDFDVTRLNQKPEPGATVHLQLMCKPHGSLLP 296
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: rnf10 (ring finger protein 10 [Source:NCBI gene;Acc:101166478])

HSP 1 Score: 62.003 bits (149), Expect = 1.450e-9
Identity = 34/131 (25.95%), Postives = 63/131 (48.09%), Query Frame = 2 
Query:   20 KYKMDNKINHRLAFIQNRCTICVYEKYKFLRNIHD----FSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLL 400
            K+   NK  ++  F+Q  C   V +   +  +  D     +W  V ++   +++   C IC    + AR+ RCGHIFC  C+L    ++  + + CP+C +  +    LK V   E +  ++G+ I + L+
Sbjct:  165 KWGHKNKPFNKELFLQANCQFVVSDDQDYKAHFTDPDTLVNWDCVQQVRIHSHEVPSCPICLYPPVAARITRCGHIFCWPCMLHYLSLSDKSWSKCPICYEA-VHTADLKSVVAMETRQYVVGDVITMRLM 294
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000076269.1 (SMESG000076269.1)

HSP 1 Score: 900.582 bits (2326), Expect = 0.000e+0
Identity = 527/536 (98.32%), Postives = 528/536 (98.51%), Query Frame = 2 
Query:   29 MDNKINHRLAFIQNRCTICVYEKYKFLRNIHDFSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSYKDYNLPKLENSISKFLSIVTEKDFRSQQDIIDDLNXXXXXXXXXXXXXXFPRXXXXXXXXXXXXXXXHFQDEIKVINKNEIDENCEIFEDNFNLIEYKNMKEKFELFYQAEGYRFVFLDQLNQKQILDKSQHTWKVVPVQIKSTIREIREEFVDNEFLMRTKLSHLFRGVKVTIVTIDLPNALLEPITGGNLRILRSHQEQIYKARKEDLDMXXXXXXXXXXXXSLPPRQRVLTTVNTENAQYSRLFDMIAEGFNTCTLGIECLVPDDDYPHAQDCEHYASAKHHLSPLETAPTDEKFLGILRMKLNVFHP-XXXXXXXNEALQPAVVTQCXXXXXXXXXXXXXXXXERLSSDELSLIKEANRIAPYIVPRKPXXXXXXXXXXXXXXXXMKAAS 1633
            MDNKINHRLAFIQNRCTICVYEKYKFLRNIHDFSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSYKDYNLPKLENSISKFLSIVTEKDFRSQQDIIDDLNLIKCKLKQKSKLNKFPRNNLEKLLLNLKSELKHFQDEIKVINKNEIDENCEIFEDNFNLIEYKNMKEKFELFYQAEGYRFVFLDQLNQKQILDKSQ TWKVVPVQIKSTIREIREEFVDNEF+MRTKLSHLFRGVKVTIVTIDLPNALLEPITGGNLRILRSHQEQIYKARKEDLDMRERIAKRAAERRSLPPRQRVLTTVNTENAQYSRLFDMIAEGFNTCTLGIECLVPDDDYPHAQDCEHYASAKHHLSPLETAPTDEKFLGILRMKLNVFHP  AAAAADNEALQPAVVTQCPSPAAA V  LLHAPPERLS DELSLIKEANRIAPYIVPRK KSQNQQKKLRKLQKQSMKAAS
Sbjct:    1 MDNKINHRLAFIQNRCTICVYEKYKFLRNIHDFSWTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSYKDYNLPKLENSISKFLSIVTEKDFRSQQDIIDDLNLIKCKLKQKSKLNKFPRNNLEKLLLNLKSELKHFQDEIKVINKNEIDENCEIFEDNFNLIEYKNMKEKFELFYQAEGYRFVFLDQLNQKQILDKSQQTWKVVPVQIKSTIREIREEFVDNEFVMRTKLSHLFRGVKVTIVTIDLPNALLEPITGGNLRILRSHQEQIYKARKEDLDMRERIAKRAAERRSLPPRQRVLTTVNTENAQYSRLFDMIAEGFNTCTLGIECLVPDDDYPHAQDCEHYASAKHHLSPLETAPTDEKFLGILRMKLNVFHPDAAAAAADNEALQPAVVTQCPSPAAAVVPLLLHAPPERLSLDELSLIKEANRIAPYIVPRKLKSQNQQKKLRKLQKQSMKAAS 536
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000016827.1 (SMESG000016827.1)

HSP 1 Score: 58.151 bits (139), Expect = 1.396e-8
Identity = 31/114 (27.19%), Postives = 57/114 (50.00%), Query Frame = 2 
Query:  101 KFLRNIHDFS-----WTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCP 427
            K L++ +DF      W S+ +I  +  +  +C IC D   ++R D+CGH++C  C+          +  C +C + EI +  +KR  F E+    +G+ I L L+ + + +  P
Sbjct:   83 KCLKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALC-NQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFP 195
The following BLAST results are available for this feature:
BLAST of RING-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
RNF104.581e-826.92ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
RNF104.793e-826.92ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
RNF102.150e-728.89ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG120992.579e-627.17gene:FBgn0035232 transcript:FBtr0072829[more]
CG120992.579e-627.17gene:FBgn0035232 transcript:FBtr0072828[more]
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf102.917e-825.19ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
zgc:664403.563e-637.31zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640][more]
zgc:664403.563e-637.31zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640][more]
zgc:664405.174e-637.31zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640][more]
zgc:664406.469e-639.29zgc:66440 [Source:ZFIN;Acc:ZDB-GENE-040426-1640][more]
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
egfl73.969e-1029.01EGF like domain multiple 7 [Source:Xenbase;Acc:XB-... [more]
egfl74.032e-1029.01EGF like domain multiple 7 [Source:Xenbase;Acc:XB-... [more]
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Rnf102.347e-826.12ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf102.802e-826.92ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf102.852e-826.92ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf102.903e-826.92ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
back to top
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q32NQ8|RNF10_XENLA1.027e-829.01RING finger protein 10 OS=Xenopus laevis OX=8355 G... [more]
sp|Q5XI59|RNF10_RAT2.786e-827.69RING finger protein 10 OS=Rattus norvegicus OX=101... [more]
sp|Q08E13|RNF10_BOVIN1.744e-726.92RING finger protein 10 OS=Bos taurus OX=9913 GN=RN... [more]
sp|Q3UIW5|RNF10_MOUSE1.995e-726.92RING finger protein 10 OS=Mus musculus OX=10090 GN... [more]
sp|Q8N5U6|RNF10_HUMAN2.200e-726.92RING finger protein 10 OS=Homo sapiens OX=9606 GN=... [more]
back to top
BLAST of RING-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3WNE41.146e-921.60RING-type domain-containing protein OS=Hydatigena ... [more]
A0A0K2TF821.580e-930.15CG12099 CG12099PBlike [Tribolium castaneum] (Fragm... [more]
A0A0K2TF842.328e-930.15CG12099 CG12099PBlike [Tribolium castaneum] OS=Lep... [more]
E9H0B13.674e-928.13RING-type domain-containing protein OS=Daphnia pul... [more]
A0A210PUY33.883e-929.11RING finger protein 10 OS=Mizuhopecten yessoensis ... [more]
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnf102.891e-925.95ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
MAG28.176e-629.13Cytoplasmic protein of unknown function; induced i... [more]
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnf101.450e-925.95ring finger protein 10 [Source:NCBI gene;Acc:10116... [more]
back to top
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000076269.10.000e+098.32SMESG000076269.1[more]
SMESG000016827.11.396e-827.19SMESG000016827.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031551 ID=SMED30031551|Name=RING-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1885bp
TACTTTTTAAAATATAATAAAATACAAAATGGATAATAAAATAAATCATA
GGCTTGCTTTCATTCAAAATAGATGTACAATATGCGTTTACGAAAAGTAC
AAGTTCTTACGAAATATTCATGATTTTTCATGGACCAGTGTATCTAAAAT
TATCTGCTTTACTAATGATTCCAAAGTTTGTTCAATATGTTTCGATAAAA
TAATATTAGCACGCATGGATCGATGTGGTCACATATTTTGCCTGTCTTGT
ATTTTAAGTGTTTTTGATGTCAACAAATCAAACCATGCGCCATGTCCAAT
GTGTAAAGATGTAGAAATCAGTATCAATTCCTTAAAACGTGTCGAGTTCC
ATGAACAGAAATTACCAATAATAGGCGAGCCTATTAAACTAAGTTTATTA
GTTAAAGGCCAACAAAATGTTTGTCCAAGATTTGCACACTTTTTAACTAG
TTATAAAGATTACAATTTACCGAAGCTTGAAAACTCGATTAGCAAATTTC
TCAGTATTGTAACTGAAAAAGATTTTCGTTCTCAGCAAGATATTATCGAT
GATCTCAATCTTATTAAATGTAAATTAAAACAGAAATCAAAATTAAACAA
ATTTCCACGAAATAATCTCGAGAAATTATTGCTGAATTTAAAAAGTGAAC
TCAAACATTTTCAAGACGAAATTAAAGTGATAAACAAAAATGAAATAGAT
GAAAATTGTGAGATTTTCGAGGATAATTTTAATTTAATTGAATATAAAAA
TATGAAAGAAAAATTCGAATTGTTCTACCAAGCCGAAGGATATCGATTTG
TGTTTCTCGATCAATTGAACCAGAAACAAATACTCGACAAGTCGCAACAT
ACTTGGAAAGTTGTGCCGGTTCAAATAAAATCCACAATCAGAGAAATTCG
GGAAGAATTTGTCGACAATGAGTTTCTAATGCGCACAAAACTGTCGCATC
TGTTCAGGGGAGTCAAAGTGACAATTGTGACAATCGATCTACCGAACGCA
TTGCTGGAACCAATAACGGGTGGAAATCTGAGGATTTTGCGCTCTCATCA
GGAACAGATTTACAAAGCCCGAAAGGAGGATTTGGACATGCGGGAAAGGA
TTGCTAAACGAGCTGCTGAACGAAGGAGTTTACCACCACGGCAACGAGTC
TTAACAACAGTAAATACCGAGAATGCTCAATATTCGCGACTATTCGACAT
GATTGCTGAGGGCTTCAACACTTGCACGCTGGGTATTGAGTGCCTGGTGC
CAGATGATGATTATCCCCATGCACAAGATTGCGAGCATTACGCCAGTGCA
AAGCACCATTTATCACCGTTGGAAACTGCTCCAACAGATGAGAAATTCCT
CGGCATATTGCGGATGAAGCTGAACGTATTCCACCCGGATGCTGCTGCTG
CTGCTGATAATGAGGCACTGCAGCCGGCTGTCGTCACCCAATGCCCGTCT
CCAGCAGCAGCAGCAGTTGTCCCCCTCCTCCATGCCCCTCCAGAACGGTT
GTCATCGGATGAGCTGTCACTCATTAAAGAGGCAAACCGTATTGCGCCAT
ATATCGTTCCCAGGAAACCGAAATCTCAGAACCAGCAAAAGAAACTGAGA
AAACTCCAGAAACAATCAATGAAGGCCGCCAGTTGATATTATGGAAATTA
TATTTTTACTTGAGTTATATATTTACAATTGGAAATTTTATGGCGGTTTT
AGAATTAGATGTCTTAATATTTGCATTTTGATCCGATCTGAGCAGTTTGA
TCCGATCGGGCATTTTGATCCGATTGAGCATTTATTGTTGGGTTTTATTT
TATTATTTTGTGTATGTGTGTGTGTCAGTACATTCTAGATATCGACTTCT
CTTATTGGTTATTACTATTGATTCGTTATTATTAG
back to top

protein sequence of SMED30031551-orf-1

>SMED30031551-orf-1 ID=SMED30031551-orf-1|Name=SMED30031551-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=536bp
MDNKINHRLAFIQNRCTICVYEKYKFLRNIHDFSWTSVSKIICFTNDSKV
CSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISIN
SLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCPRFAHFLTSYKDYNLPKL
ENSISKFLSIVTEKDFRSQQDIIDDLNLIKCKLKQKSKLNKFPRNNLEKL
LLNLKSELKHFQDEIKVINKNEIDENCEIFEDNFNLIEYKNMKEKFELFY
QAEGYRFVFLDQLNQKQILDKSQHTWKVVPVQIKSTIREIREEFVDNEFL
MRTKLSHLFRGVKVTIVTIDLPNALLEPITGGNLRILRSHQEQIYKARKE
DLDMRERIAKRAAERRSLPPRQRVLTTVNTENAQYSRLFDMIAEGFNTCT
LGIECLVPDDDYPHAQDCEHYASAKHHLSPLETAPTDEKFLGILRMKLNV
FHPDAAAAADNEALQPAVVTQCPSPAAAAVVPLLHAPPERLSSDELSLIK
EANRIAPYIVPRKPKSQNQQKKLRKLQKQSMKAAS*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000101muscle cell
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR039739Mag2/Rnf10
IPR001841Znf_RING
IPR013083Znf_RING/FYVE/PHD
IPR018957Znf_C3HC4_RING-type
IPR017907Znf_RING_CS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0046872metal ion binding
GO:0003677DNA binding
GO:0044212transcription regulatory region DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
Vocabulary: biological process
TermDefinition
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0010626negative regulation of Schwann cell proliferation
GO:0031643positive regulation of myelination
GO:0045944positive regulation of transcription from RNA polymerase II promoter
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 194..221
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 517..536
NoneNo IPR availableCDDcd16536RING-HC_RNF10coord: 51..92
e-value: 2.21977E-14
score: 65.2781
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 30..96
IPR001841Zinc finger, RING-typeSMARTSM00184ring_2coord: 51..92
e-value: 1.5E-6
score: 37.7
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 51..93
score: 12.357
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 30..115
e-value: 3.5E-10
score: 41.5
IPR018957Zinc finger, C3HC4 RING-typePFAMPF00097zf-C3HC4coord: 51..92
e-value: 3.9E-7
score: 29.8
IPR039739RING-finger protein Mag2/Rnf10PANTHERPTHR12983FAMILY NOT NAMEDcoord: 3..372
IPR017907Zinc finger, RING-type, conserved sitePROSITEPS00518ZF_RING_1coord: 66..75