Tyrosine-protein kinase

Overview


Name	Tyrosine-protein kinase
Smed ID	SMED30031519
Length (bp)	2207

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Tyrosine-protein kinase (SMED30031519) t-SNE clustered cells

Violin plots show distribution of expression levels for Tyrosine-protein kinase (SMED30031519) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tyrosine-protein kinase (SMED30031519) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tyrosine-protein kinase (SMED30031519) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30031519

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30031519	SMESG000020289.1	dd_Smed_v4_9416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
photoreceptor neuron	SMED30031519	SMESG000020289.1	SMED30031519	smed_20140614	PMID:22884275 Lapan et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: FYN (FYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4037])

HSP 1 Score: 521.546 bits (1342), Expect = 3.663e-178
Identity = 248/472 (52.54%), Postives = 324/472 (68.64%), Query Frame = 1

Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++   KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE M+KGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP  ++E+M+ CW   PE RPTF  L+   +D F   E  Y+  E
Sbjct:   66 GVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGE 535

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Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++   KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE M+KGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP  ++E+M+ CW   PE RPTF  L+   +D F   E  Y+  E
Sbjct:   66 GVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGE 535

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BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283])

HSP 1 Score: 508.064 bits (1307), Expect = 7.203e-173
Identity = 240/451 (53.22%), Postives = 316/451 (70.07%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  KKG+R+ ++ + + DWWL    +TG  GY+PS+++A   S ++++WYF  ITR+++ER LL   N RG FL+R SETT+GA CLSV D     G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+ ETG+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CP  ++++M QCW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   89 FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE 534

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Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  KKG+R+ ++ + + DWWL    +TG  GY+PS+++A   S ++++WYF  ITR+++ER LL   N RG FL+R SETT+GA CLSV D     G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+ ETG+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CP  ++++M QCW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   89 FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE 534

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Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  KKG+R+ ++ + + DWWL    +TG  GY+PS+++A   S ++++WYF  ITR+++ER LL   N RG FL+R SETT+GA CLSV D     G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+ ETG+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CP  ++++M QCW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   89 FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE 534

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BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 454.521 bits (1168), Expect = 2.475e-153
Identity = 220/455 (48.35%), Postives = 304/455 (66.81%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLD-HPVNSGYVVNHYKIKKTNQGAVY-ITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEG----EICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIY-EIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGY 1857
            L+A++ Y +R   ++  +KGD + LL+ ++ DWW V  + TG  GYVP +F+A + + ES++WY   I R  AER +L     +G FLIR  E       L++ D     +G  V HYKIK+ +    Y ITT++ F SL +L+ YYS+ P+GLCC L+ P  +  P   DLS+ T+  WEI R+ L L  KLG G FGEVW G W G   VA+KT+KPGTM+ E FL+EA++MK   H NLV+LYA+C+ +EP YI+TE M  GSLLQYLR++ G  + ++ L+D  +QIANGM YLE    VHRDLAARN+LVG+      + K+ADFGLAR +    ++YEA  G++FP+KWTAPEAA  G F+ KSDVWS+G+L+YEI+T+GQVP+P M N E ++ +E GYRMP P+ CP  IY E++L+CW+  P+ RPTF +L   FDD F++ +  Y
Sbjct:   20 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKL-MEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 472

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BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 455.677 bits (1171), Expect = 5.441e-153
Identity = 221/456 (48.46%), Postives = 306/456 (67.11%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLD-HPVNSGYVVNHYKIKKTNQGAVY-ITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEG----EICKIADFGLAR-LIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIY-EIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGY 1857
            L+A++ Y +R   ++  +KGD + LL+ ++ DWW V  + TG  GYVP +F+A + + ES++WY   I R  AER +L     +G FLIR  E       L++ D     +G  V HYKIK+ +    Y ITT++ F SL +L+ YYS+ P+GLCC L+ P  +  P   DLS+ T+  WEI R+ L L  KLG G FGEVW G W G   VA+KT+KPGTM+ E FL+EA++MK   H NLV+LYA+C+ +EP YI+TE M  GSLLQYLR++ G  + ++ L+D  +QIANGM YLE    VHRDLAARN+LVG+      + K+ADFGLAR L++   ++YEA  G++FP+KWTAPEAA  G F+ KSDVWS+G+L+YEI+T+GQVP+P M N E ++ +E GYRMP P+ CP  IY E++L+CW+  P+ RPTF +L   FDD F++ +  Y
Sbjct:   76 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEE--DIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 528

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Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLD-HPVNSGYVVNHYKIKKTNQGAVY-ITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEG----EICKIADFGLAR-LIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIY-EIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGY 1857
            L+A++ Y +R   ++  +KGD + LL+ ++ DWW V  + TG  GYVP +F+A + + ES++WY   I R  AER +L     +G FLIR  E       L++ D     +G  V HYKIK+ +    Y ITT++ F SL +L+ YYS+ P+GLCC L+ P  +  P   DLS+ T+  WEI R+ L L  KLG G FGEVW G W G   VA+KT+KPGTM+ E FL+EA++MK   H NLV+LYA+C+ +EP YI+TE M  GSLLQYLR++ G  + ++ L+D  +QIANGM YLE    VHRDLAARN+LVG+      + K+ADFGLAR L++   ++YEA  G++FP+KWTAPEAA  G F+ KSDVWS+G+L+YEI+T+GQVP+P M N E ++ +E GYRMP P+ CP  IY E++L+CW+  P+ RPTF +L   FDD F++ +  Y
Sbjct:   76 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEE--DIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 528

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BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 455.292 bits (1170), Expect = 9.862e-153
Identity = 221/456 (48.46%), Postives = 306/456 (67.11%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLD-HPVNSGYVVNHYKIKKTNQGAVY-ITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEG----EICKIADFGLAR-LIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIY-EIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGY 1857
            L+A++ Y +R   ++  +KGD + LL+ ++ DWW V  + TG  GYVP +F+A + + ES++WY   I R  AER +L     +G FLIR  E       L++ D     +G  V HYKIK+ +    Y ITT++ F SL +L+ YYS+ P+GLCC L+ P  +  P   DLS+ T+  WEI R+ L L  KLG G FGEVW G W G   VA+KT+KPGTM+ E FL+EA++MK   H NLV+LYA+C+ +EP YI+TE M  GSLLQYLR++ G  + ++ L+D  +QIANGM YLE    VHRDLAARN+LVG+      + K+ADFGLAR L++   ++YEA  G++FP+KWTAPEAA  G F+ KSDVWS+G+L+YEI+T+GQVP+P M N E ++ +E GYRMP P+ CP  IY E++L+CW+  P+ RPTF +L   FDD F++ +  Y
Sbjct:   80 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEE--DIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 532

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Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLD-HPVNSGYVVNHYKIKKTNQGAVY-ITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEG----EICKIADFGLAR-LIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIY-EIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGY 1857
            L+A++ Y +R   ++  +KGD + LL+ ++ DWW V  + TG  GYVP +F+A + + ES++WY   I R  AER +L     +G FLIR  E       L++ D     +G  V HYKIK+ +    Y ITT++ F SL +L+ YYS+ P+GLCC L+ P  +  P   DLS+ T+  WEI R+ L L  KLG G FGEVW G W G   VA+KT+KPGTM+ E FL+EA++MK   H NLV+LYA+C+ +EP YI+TE M  GSLLQYLR++ G  + ++ L+D  +QIANGM YLE    VHRDLAARN+LVG+      + K+ADFGLAR L++   ++YEA  G++FP+KWTAPEAA  G F+ KSDVWS+G+L+YEI+T+GQVP+P M N E ++ +E GYRMP P+ CP  IY E++L+CW+  P+ RPTF +L   FDD F++ +  Y
Sbjct:   80 LVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTD-GSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEE--DIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNY 532

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BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src42A (gene:FBgn0264959 transcript:FBtr0335275)

HSP 1 Score: 484.182 bits (1245), Expect = 3.595e-164
Identity = 228/458 (49.78%), Postives = 317/458 (69.21%), Query Frame = 1

Query:  511 RFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSK-PTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQ--LIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAEC 1872
            +  +A++DY ART +++  +KG+ + +L     DWWL   + T + GY+PS+++A   S E++ WYF  I R +AE+ LL P N  G FLIR SE+      LSV D     G  V HY+I++ ++G  +I  +  F +L +L+ +YS   +GLC +L  PC +   P+   LS++T+D+WEIDR+SL+   KLG+GQFG+VW GLWN TTPVA+KTLK GTM  +DFL EA++MK L H  L++LYA+C+ +EPIYI+TELM  GSLL+YL++  G+   LK   LID  +QIA GMAYLE+  Y+HRDLAARN+LVG+G I KIADFGLARLI    + YEA  G+RFP+KWTAPEAA + KFS KSDVWSFG+L+ E++T G++P+P M+N+E L  +E GYRMP P  C   +YEIML+CW+  P  RPTF +L+   +D + + +S Y+ A+ 
Sbjct:   66 KIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRD-----GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKE--DEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQA 516

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BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100508)

HSP 1 Score: 448.743 bits (1153), Expect = 7.354e-150
Identity = 222/456 (48.68%), Postives = 295/456 (64.69%), Query Frame = 1

Query:  511 RFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQ--CPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            R ++A++DYK+R   ++   KGDR+ +++  + DWW V    T   G +P +F+A E S  S+DW+F  + RK+A++ LL   N RG FL+R SE       LSV D     GY V HY+IK  + G  YI T + FPSL  L++ YS    GLC  LS PC KP P + DL  + +DK+EI RS +QL  KLG G FGEV+ G W  +  VAVKTL+ GTM+   FL+EA +MK   H  LV LYA+CS +EPIYIV E MSKGSLL +LR   G+ +  + LI   +Q+A+GM YLE+   +HRDLAARN+L+GE  + KI DFGLAR+I    + Y   QGSRFPVKWTAPEA ++GKFS KSDVWS+G+L+ E+ T GQVP+P M + E ++NIE G+RMP P     P  IY+++LQCW+  PE RPTF  L   F+   +T+E  YR  +
Sbjct:   98 RVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI--ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYREVQ 551

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BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100505)

HSP 1 Score: 448.743 bits (1153), Expect = 7.354e-150
Identity = 222/456 (48.68%), Postives = 295/456 (64.69%), Query Frame = 1

Query:  511 RFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQ--CPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            R ++A++DYK+R   ++   KGDR+ +++  + DWW V    T   G +P +F+A E S  S+DW+F  + RK+A++ LL   N RG FL+R SE       LSV D     GY V HY+IK  + G  YI T + FPSL  L++ YS    GLC  LS PC KP P + DL  + +DK+EI RS +QL  KLG G FGEV+ G W  +  VAVKTL+ GTM+   FL+EA +MK   H  LV LYA+CS +EPIYIV E MSKGSLL +LR   G+ +  + LI   +Q+A+GM YLE+   +HRDLAARN+L+GE  + KI DFGLAR+I    + Y   QGSRFPVKWTAPEA ++GKFS KSDVWS+G+L+ E+ T GQVP+P M + E ++NIE G+RMP P     P  IY+++LQCW+  PE RPTF  L   F+   +T+E  YR  +
Sbjct:   98 RVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI--ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYREVQ 551

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BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100504)

HSP 1 Score: 448.743 bits (1153), Expect = 7.354e-150
Identity = 222/456 (48.68%), Postives = 295/456 (64.69%), Query Frame = 1

Query:  511 RFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQ--CPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            R ++A++DYK+R   ++   KGDR+ +++  + DWW V    T   G +P +F+A E S  S+DW+F  + RK+A++ LL   N RG FL+R SE       LSV D     GY V HY+IK  + G  YI T + FPSL  L++ YS    GLC  LS PC KP P + DL  + +DK+EI RS +QL  KLG G FGEV+ G W  +  VAVKTL+ GTM+   FL+EA +MK   H  LV LYA+CS +EPIYIV E MSKGSLL +LR   G+ +  + LI   +Q+A+GM YLE+   +HRDLAARN+L+GE  + KI DFGLAR+I    + Y   QGSRFPVKWTAPEA ++GKFS KSDVWS+G+L+ E+ T GQVP+P M + E ++NIE G+RMP P     P  IY+++LQCW+  PE RPTF  L   F+   +T+E  YR  +
Sbjct:   98 RVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI--ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYREVQ 551

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BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0304990)

HSP 1 Score: 448.743 bits (1153), Expect = 7.354e-150
Identity = 222/456 (48.68%), Postives = 295/456 (64.69%), Query Frame = 1

Query:  511 RFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQ--CPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            R ++A++DYK+R   ++   KGDR+ +++  + DWW V    T   G +P +F+A E S  S+DW+F  + RK+A++ LL   N RG FL+R SE       LSV D     GY V HY+IK  + G  YI T + FPSL  L++ YS    GLC  LS PC KP P + DL  + +DK+EI RS +QL  KLG G FGEV+ G W  +  VAVKTL+ GTM+   FL+EA +MK   H  LV LYA+CS +EPIYIV E MSKGSLL +LR   G+ +  + LI   +Q+A+GM YLE+   +HRDLAARN+L+GE  + KI DFGLAR+I    + Y   QGSRFPVKWTAPEA ++GKFS KSDVWS+G+L+ E+ T GQVP+P M + E ++NIE G+RMP P     P  IY+++LQCW+  PE RPTF  L   F+   +T+E  YR  +
Sbjct:   98 RVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI--ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYREVQ 551

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BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: fyna (FYN proto-oncogene, Src family tyrosine kinase a [Source:NCBI gene;Acc:373872])

HSP 1 Score: 524.628 bits (1350), Expect = 1.144e-179
Identity = 244/452 (53.98%), Postives = 320/452 (70.80%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              +A++DY+AR+ D++  +KG++  +L S + DWW      TG  GY+PS+++A   S +++DWYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VAVKTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+ + L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CPS ++E+MLQCW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   86 LFVALYDYEARSEDDLSFRKGEKFQILNSTEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSNGNPRGTFLIRESETTKGAYSLSIQDWDETKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVHHYSARAAGLCCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQPGD 535

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BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: fynb (FYN proto-oncogene, Src family tyrosine kinase b [Source:NCBI gene;Acc:574422])

HSP 1 Score: 517.309 bits (1331), Expect = 1.384e-176
Identity = 240/452 (53.10%), Postives = 318/452 (70.35%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              +A++DY+ART D++  +KG++  ++ S + DWW      TG  GY+PS+++A   S +++DWYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +Y+    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE M KGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+GKF+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRM  P+ CPS ++E+M+QCW    E RPTF  L+   +D F   E  Y+  +
Sbjct:   93 LFVALYDYEARTEDDLSFRKGEKFQIINSTEGDWWDARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPRGTFLIRESETTKGAFSLSIRDWDDVKGDHVKHYKIRKLDSGGYYITTRAQFETLQQLVQHYTERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPQDCPSSLHELMVQCWKKDAEERPTFEYLQAFLEDYFTATEPQYQPGD 542

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Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              +A++DY+ART D++  +KG++  ++ S + DWW      TG  GY+PS+++A   S +++DWYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +Y+    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE M KGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+GKF+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRM  P+ CPS ++E+M+QCW    E RPTF  L+   +D F   E  Y+  +
Sbjct:   93 LFVALYDYEARTEDDLSFRKGEKFQIINSTEGDWWDARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPRGTFLIRESETTKGAFSLSIRDWDDVKGDHVKHYKIRKLDSGGYYITTRAQFETLQQLVQHYTERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPQDCPSSLHELMVQCWKKDAEERPTFEYLQAFLEDYFTATEPQYQPGD 542

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BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: yrk (Yes-related kinase [Source:ZFIN;Acc:ZDB-GENE-030131-9517])

HSP 1 Score: 509.605 bits (1311), Expect = 6.383e-174
Identity = 240/452 (53.10%), Postives = 318/452 (70.35%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              IA+++Y ART D++  +KG++  ++ + + DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL   N RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F ++ QL+ +Y+    GLCC L   C +  P ++DLS KTKD WEI R SLQL +KLG GQFGEVW G+WNGTT VAVKTLKPGTM+ E FL EA++MK L H  LV+LYA+ S+EPIYI+TE MS+GSLL +L+   G+ + L QL+D  +QIA GMAY+E   Y+HRDL A NILVG+G +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+GKF+ KSDVWSFG+L+ E+IT+G+VP+P M+N E L+ +E GYRMP P+  P+ ++E+MLQCW   P+ R TF  L+   +D F   E  Y+  E
Sbjct:   77 LFIALYEYDARTEDDLSFQKGEKFHIINNTEGDWWEARSLDTGKSGYIPSNYVAPVDSIQAEEWYFGKMGRKDAERQLLAQNNPRGTFLIRESETTKGAYSLSIRDWDDAKGDHVKHYKIRKLDNGGYYITTRTQFDTVQQLVEHYTERAAGLCCRLIGSCRRGMPKLADLSVKTKDVWEIPRESLQLIKKLGNGQFGEVWMGMWNGTTKVAVKTLKPGTMSPEAFLDEAQIMKRLRHDKLVQLYAVVSEEPIYIITEFMSQGSLLDFLKDGDGRNLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDGLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVERGYRMPCPQGSPASLHELMLQCWRKDPDERHTFEYLQSFLEDYFTATEPQYQPGE 526

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Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              IA+++Y ART D++  +KG++  ++ + + DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL   N RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F ++ QL+ +Y+    GLCC L   C +  P ++DLS KTKD WEI R SLQL +KLG GQFGEVW G+WNGTT VAVKTLKPGTM+ E FL EA++MK L H  LV+LYA+ S+EPIYI+TE MS+GSLL +L+   G+ + L QL+D  +QIA GMAY+E   Y+HRDL A NILVG+G +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+GKF+ KSDVWSFG+L+ E+IT+G+VP+P M+N E L+ +E GYRMP P+  P+ ++E+MLQCW   P+ R TF  L+   +D F   E  Y+  E
Sbjct:   77 LFIALYEYDARTEDDLSFQKGEKFHIINNTEGDWWEARSLDTGKSGYIPSNYVAPVDSIQAEEWYFGKMGRKDAERQLLAQNNPRGTFLIRESETTKGAYSLSIRDWDDAKGDHVKHYKIRKLDNGGYYITTRTQFDTVQQLVEHYTERAAGLCCRLIGSCRRGMPKLADLSVKTKDVWEIPRESLQLIKKLGNGQFGEVWMGMWNGTTKVAVKTLKPGTMSPEAFLDEAQIMKRLRHDKLVQLYAVVSEEPIYIITEFMSQGSLLDFLKDGDGRNLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDGLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVERGYRMPCPQGSPASLHELMLQCWRKDPDERHTFEYLQSFLEDYFTATEPQYQPGE 526

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BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ccdc13 (coiled-coil domain containing 13 [Source:Xenbase;Acc:XB-GENE-992948])

HSP 1 Score: 520.776 bits (1340), Expect = 1.198e-178
Identity = 244/455 (53.63%), Postives = 321/455 (70.55%), Query Frame = 1

Query:  505 RNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            R    +A++DY+ART D++  +KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG +LIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG +FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP+ ++E+ML CW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   33 RVTLFVALYDYEARTEDDLSFQKGEKFQILNSSEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTYLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGMKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPNSLHELMLNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGD 485

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BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ccdc13 (coiled-coil domain containing 13 [Source:Xenbase;Acc:XB-GENE-992948])

HSP 1 Score: 520.776 bits (1340), Expect = 1.752e-178
Identity = 246/460 (53.48%), Postives = 324/460 (70.43%), Query Frame = 1

Query:  496 DIH--RNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            D+H  R    +A++DY+ART D++  +KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG +LIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG +FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP+ ++E+ML CW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   39 DLHALRVTLFVALYDYEARTEDDLSFQKGEKFQILNSSEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTYLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGMKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPNSLHELMLNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGD 496

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BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ccdc13 (coiled-coil domain containing 13 [Source:Xenbase;Acc:XB-GENE-992948])

HSP 1 Score: 521.161 bits (1341), Expect = 3.870e-178
Identity = 248/472 (52.54%), Postives = 325/472 (68.86%), Query Frame = 1

Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++  +KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG +LIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG +FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP+ ++E+ML CW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   67 GVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFQKGEKFQILNSSEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTYLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGMKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPNSLHELMLNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGD 536

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BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: FGR (FGR proto-oncogene, Src family tyrosine kinase [Source:NCBI gene;Acc:100493811])

HSP 1 Score: 505.753 bits (1301), Expect = 4.546e-173
Identity = 243/469 (51.81%), Postives = 323/469 (68.87%), Query Frame = 1

Query:  469 TSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECI 1875
            T   + ++T +   R  IA++DY ART D++  KKG++  ++ +++ DWW     ++GN GY+PS+++A   S +S+DWYF  I RKDAER LL  GN RG F+IR SETT+GA  LSV D     G    HYKI+K + G  YITT+  F ++ +L+ +YS   +GLC  L++PC    P    LS   KD WEI R S+ L +KLG G FG+VW+G WNGTT VAVKTLKP TM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE M+KGSLL YL+   G  + L QL+D   QIA+GMAY+E   Y+HRDL A NILVG+  ICKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+GKF+ KSDVWSFG+++ E++T+G++P+P MSN E L+ +E GYRMP+P  CP  ++E+MLQCW   PE RPTF  L+   +D F   E  Y+  + I
Sbjct:    5 TRAGFINRTSMQPLRNFIALYDYDARTEDDLTFKKGEKFHIINNSEGDWWEARSLSSGNTGYIPSNYVAPMNSIQSKDWYFGKIGRKDAERLLLCEGNPRGTFMIRESETTKGAYSLSVRDWDATRGDHAKHYKIRKLDNGGFYITTRVQFDTVEELVEHYSEFNDGLCHLLTNPCINQKPQTLGLS---KDAWEITRDSISLDKKLGQGCFGDVWKGTWNGTTNVAVKTLKPSTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEFMTKGSLLDYLKEGEGHLLKLPQLVDMSGQIASGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGIMVCELVTKGRIPYPGMSNREVLEQVERGYRMPAPPACPPSLHELMLQCWRGDPEERPTFEYLQSFLEDYFTATEPQYQPGDNI 468

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BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161])

HSP 1 Score: 504.212 bits (1297), Expect = 3.597e-172
Identity = 243/466 (52.15%), Postives = 319/466 (68.45%), Query Frame = 1

Query:  472 STNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            S N+G  T        +A++DY++RT  ++  KKG+R+ ++ + + DWWL    ++G  GY+PS+++A   S ++++WY   ITR++AER LL   N RG FL+R SETT+GA CLSV D+  N G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    LS   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+ E G+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P  CP  ++++M QCW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   33 SKNHGGVTT------FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLS---KDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQPGD 487

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BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Fyn (Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602])

HSP 1 Score: 522.702 bits (1345), Expect = 7.885e-179
Identity = 249/472 (52.75%), Postives = 324/472 (68.64%), Query Frame = 1

Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++   KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP  ++E+M+ CW   PE RPTF  L+   +D F   E  Y+  E
Sbjct:   66 GVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGE 535

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BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397])

HSP 1 Score: 506.138 bits (1302), Expect = 2.132e-172
Identity = 239/451 (52.99%), Postives = 316/451 (70.07%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  KKG+R+ ++ + + DWWL    +TG  GY+PS+++A   S ++++WYF  ITR+++ER LL   N RG FL+R SETT+GA CLSV D     G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE M+KGSLL +L+ ETG+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CP  ++++M QCW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   88 FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE 533

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Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  KKG+R+ ++ + + DWWL    +TG  GY+PS+++A   S ++++WYF  ITR+++ER LL   N RG FL+R SETT+GA CLSV D     G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE M+KGSLL +L+ ETG+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CP  ++++M QCW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   88 FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE 533

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Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  KKG+R+ ++ + + DWWL    +TG  GY+PS+++A   S ++++WYF  ITR+++ER LL   N RG FL+R SETT+GA CLSV D     G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE M+KGSLL +L+ ETG+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CP  ++++M QCW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   88 FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE 533

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BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397])

HSP 1 Score: 499.975 bits (1286), Expect = 8.015e-170
Identity = 239/457 (52.30%), Postives = 316/457 (69.15%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILL------ESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  KKG+R+ ++      +  + DWWL    +TG  GY+PS+++A   S ++++WYF  ITR+++ER LL   N RG FL+R SETT+GA CLSV D     G  V HYKI+K + G  YIT++  F SL QL+ YYS   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE M+KGSLL +L+ ETG+ + L QL+D  +QIA+GMAY+E   YVHRDL A NILVGE  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CP  ++++M QCW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   88 FVALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLA---KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE 539

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BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P27446|FYN_XIPHE (Tyrosine-protein kinase Fyn OS=Xiphophorus helleri OX=8084 GN=fyn PE=2 SV=3)

HSP 1 Score: 529.25 bits (1362), Expect = 1.403e-180
Identity = 251/472 (53.18%), Postives = 328/472 (69.49%), Query Frame = 1

Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++  +KG+R  +L S + DWW      TG  GY+PS+++A   S +++DWYF  + RKDAER LL  GN RG +LIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS+   GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNGTT VAVKTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP+ ++E+MLQCW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   66 GVNTSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFRKGERFQILNSTEGDWWDARSLTTGGSGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPRGTYLIRESETTKGAFSLSIRDWDDEKGDHVKHYKIRKLDSGGYYITTRAQFDTLQQLVQHYSDRAAGLCCRLVVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGTTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDNLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPASLHELMLQCWKKDPEERPTFEYLQAFLEDYFTATEPQYQPGD 535

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BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|Q6EWH2|FYNA_DANRE (Tyrosine-protein kinase fyna OS=Danio rerio OX=7955 GN=fyna PE=1 SV=2)

HSP 1 Score: 524.628 bits (1350), Expect = 8.639e-179
Identity = 244/452 (53.98%), Postives = 320/452 (70.80%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              +A++DY+AR+ D++  +KG++  +L S + DWW      TG  GY+PS+++A   S +++DWYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VAVKTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+ + L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CPS ++E+MLQCW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   86 LFVALYDYEARSEDDLSFRKGEKFQILNSTEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSNGNPRGTFLIRESETTKGAYSLSIQDWDETKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVHHYSARAAGLCCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQPGD 535

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BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P39688|FYN_MOUSE (Tyrosine-protein kinase Fyn OS=Mus musculus OX=10090 GN=Fyn PE=1 SV=4)

HSP 1 Score: 522.702 bits (1345), Expect = 5.515e-178
Identity = 249/472 (52.75%), Postives = 324/472 (68.64%), Query Frame = 1

Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++   KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP  ++E+M+ CW   PE RPTF  L+   +D F   E  Y+  E
Sbjct:   66 GVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGE 535

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BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P13406|FYN_XENLA (Tyrosine-protein kinase Fyn OS=Xenopus laevis OX=8355 GN=fyn PE=2 SV=3)

HSP 1 Score: 521.546 bits (1342), Expect = 1.545e-177
Identity = 248/472 (52.54%), Postives = 325/472 (68.86%), Query Frame = 1

Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++  +KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG +LIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP  ++E+ML CW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   66 GVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFQKGEKFQILNSSEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTYLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGD 535

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BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P06241|FYN_HUMAN (Tyrosine-protein kinase Fyn OS=Homo sapiens OX=9606 GN=FYN PE=1 SV=3)

HSP 1 Score: 521.546 bits (1342), Expect = 1.759e-177
Identity = 248/472 (52.54%), Postives = 324/472 (68.64%), Query Frame = 1

Query:  472 STNYGSKTDIHRNR------FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              N  S T   R R        +A++DY+ART D++   KG++  +L S++ DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNG T VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE M+KGSLL +L+   G+A+ L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG G ICKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP  ++E+M+ CW   PE RPTF  L+   +D F   E  Y+  E
Sbjct:   66 GVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGE 535

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BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A0V0J867 (Tyrosine-protein kinase OS=Schistocephalus solidus OX=70667 GN=TR96230 PE=3 SV=1)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 271/458 (59.17%), Postives = 341/458 (74.45%), Query Frame = 1

Query:  472 STNYGSKTDIHRN--RFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKK-TNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLF 1836
            + N    T   RN  R  +AIFDY+A + +++ +++ DR+++L+ +D DWWLVE  AT   GYVPS++LA E S E  +WYF  I+RKD+ER LL  GN RG FL+R SETTQGA  LSV DH  N G +VNHYKIK   + GAV IT+KK FP+L  L+  Y+   +GLCC L++ C +P P++SDLS +TKD WEI RS L L EKLG GQFGEVW+G WNGTTPVAVKT++PGTM+KE+FLKEA++MK+L H  LVRLYA+ + EPI+IVTELMS GSLL YLRSE G+A+ LKQ +D ++QIA+GM+YLE    VHRDLAARN+LVGE    K+ADFGLAR ID   E Y A QG++FP+KWTAPEAAL G+F+ KSDVWS+GV++YEIIT GQVPFPSM+N+E LQ +  GYRMP P  CP  IY +ML+ W   P  RP+F+SL   F+D F
Sbjct:  260 TVNSADSTRQSRNTARNFVAIFDYQAHSKEDLSVRRQDRLVVLDKSDSDWWLVENPATSCHGYVPSAYLAEEGSVEVYEWYFREISRKDSERLLLLNGNVRGTFLVRESETTQGALSLSVRDHDPNRGDIVNHYKIKPYGDDGAVCITSKKGFPNLVALVRNYTEHADGLCCRLTNYCPRPPPVLSDLSKRTKDHWEIPRSQLVLQEKLGNGQFGEVWKGEWNGTTPVAVKTMRPGTMSKEEFLKEARIMKTLNHPRLVRLYAVVTTEPIFIVTELMSNGSLLHYLRSEAGKALDLKQQVDIMAQIADGMSYLEAKDLVHRDLAARNVLVGESNEVKVADFGLARQIDRDTEAYNAKQGAKFPIKWTAPEAALLGQFTVKSDVWSYGVVLYEIITYGQVPFPSMANTEILQQVSDGYRMPCPNNCPPVIYAVMLRTWEEDPNKRPSFSSLCGYFEDYF 717

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BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A3Q0KT01 (Tyrosine-protein kinase OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 570.081 bits (1468), Expect = 0.000e+0
Identity = 275/453 (60.71%), Postives = 346/453 (76.38%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQ-GAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            + +AIFDY+A T +E+  +KGD++ +L+ +D +WWLVE   +G  GY+PSS+LA   S E++DWYF  I+RKD+ER LL  GN RG FL+RASETT GA  LSV D     G  V HYKIK++++   VYITTK++FP L  L+++YSN  +GLCC L+ PC +P P+ +DLS  T+D+WEI RSSL+L E LGAGQFGEVW+G WN T  VAVKTLK GTMTKE+FLKEA++MK L H  LVRLYA+ + EPIYI+TELM  GSLL+YLR   G+ + LK LID ++QIA+GMAYLE   Y+HRDLAARNILVGE    K+ADFGLAR+ID+G E Y A QG++FP+KWTAPEAAL G+F+ KSDVWSFG++IYEIIT GQVPFPSM+N+E LQ +E GYRMP P  CP+ IYEIML  W+ +PE RPTFA L + F+D F +AE  YR A+
Sbjct:  337 YHVAIFDYEAHTSEEVSARKGDQLRVLDLSDSEWWLVEH--SGQVGYIPSSYLAQANSVEAEDWYFRSISRKDSERLLLLKGNIRGTFLVRASETTNGALSLSVRDTEQQRGETVKHYKIKQSSETNDVYITTKQVFPDLKSLVIHYSNQADGLCCCLTRPCPRPPPVPTDLSRLTRDQWEISRSSLKLIELLGAGQFGEVWKGKWNETIEVAVKTLKQGTMTKEEFLKEARIMKQLHHPRLVRLYAVVTAEPIYIITELMKNGSLLKYLRDGPGKELGLKPLIDMMAQIASGMAYLEKEHYIHRDLAARNILVGENNSVKVADFGLARIIDSGNETYTAKQGAKFPIKWTAPEAALMGRFTIKSDVWSFGIVIYEIITYGQVPFPSMNNTETLQQVENGYRMPCPINCPNSIYEIMLNTWDAKPECRPTFAFLCNYFEDYFTSAELSYRPAD 787

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BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A4Z2CUE7 (Tyrosine-protein kinase OS=Schistosoma japonicum OX=6182 GN=EWB00_007520 PE=3 SV=1)

HSP 1 Score: 568.54 bits (1464), Expect = 0.000e+0
Identity = 276/452 (61.06%), Postives = 344/452 (76.11%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQ-GAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAA 1866
            + +AIFDY+A T +E+  +KGD + +L+ +D +WWLVE   +G  GY+PSS+LA   S E++DWYF  I+RKD+ER LL  GN RG FL+RASETT GA  LSV D     G  V HYKIK+ ++ G VYITTK++F  L  L+++YSN P+GLCC L+ PC +P P+ +DLS  T+D+WEI RSSL+L E LGAGQFGEVW+G WN T  VAVKTLK GTMTKE+FLKEA++MK L H  LVRLYA+ + EPIYIVTELM+ GSLL+YLR   G+ + LK LID ++QIA+GMAYLE   Y+HRDLAARNILVGE    K+ADFGLAR+ID+  + Y A QG++FP+KWTAPEAAL G+F+ KSDVWSFG++IYEIIT GQVPFPSM+N+E LQ +E GYRMP P  CP+ IYEIML  W+ RPE RPTFA L + F+D F +AE  YR A
Sbjct:  329 YHVAIFDYEAHTAEEVSARKGDLLRVLDLSDSEWWLVEH--SGQVGYIPSSYLAQANSVEAEDWYFRSISRKDSERLLLLKGNIRGTFLVRASETTNGALSLSVRDTEQQRGETVKHYKIKQCHETGDVYITTKQVFSDLKSLVIHYSNQPDGLCCCLTRPCPRPPPVPTDLSRLTRDQWEISRSSLKLIELLGAGQFGEVWKGKWNETIEVAVKTLKQGTMTKEEFLKEARIMKQLHHPRLVRLYAVVTAEPIYIVTELMTNGSLLKYLRDGPGKELGLKPLIDMMAQIASGMAYLEKEHYIHRDLAARNILVGENNSVKVADFGLARIIDSANDTYTAKQGAKFPIKWTAPEAALMGRFTIKSDVWSFGIVIYEIITYGQVPFPSMNNTETLQQVENGYRMPCPINCPNSIYEIMLNTWDARPECRPTFAFLCNYFEDYFTSAELSYRPA 778

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BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A4E0S0K6 (Tyrosine-protein kinase OS=Fasciola hepatica OX=6192 GN=D915_003399 PE=3 SV=1)

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 267/452 (59.07%), Postives = 340/452 (75.22%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQ-GAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAA 1866
            + + IFDY  +  +E+ ++KGD++ +L+ +D +WWL E   +G  GY+PSS+LA  +S E++DWYF  I+RKD+ER LL  GN RG FL+R SETT GA  LSV D  ++ G  V HYKIK+T +   VYITTK+I P L  L+ +YS   +GLCC L+ PC +P P+ +DLS  T+D+WEI RSSL L E+LG+GQFG+VW+G WNGTT VA+KTLK GTM++EDFLKEAK+MK L H  LVRLYA+ + EPIYIVTELM  GSLL YLR   GQ + L+ L+D ++QIA+GMAYLE  GY+HRDLAARNILVGE    K+ADFGLAR+ID+G E Y A QG++FP+KWTAPEAAL G+F+ KSDVWSFG++IYEI+T GQVPFPSM+N+E LQ +++GYRMP P  CP  IYE+ML  W+  PE+RPTFA L   F+D F  AE  YR A
Sbjct:  335 YHVTIFDYVTKEAEELRVRKGDKIRVLDMSDSEWWLAEHLHSGLVGYIPSSYLAPAHSVEAEDWYFRNISRKDSERLLLLKGNIRGTFLVRESETTDGALSLSVRDTEMHRGDTVKHYKIKRTGKRDEVYITTKQILPDLKALVAHYSAQADGLCCCLTRPCPRPPPVPNDLSRLTRDQWEIPRSSLALIERLGSGQFGDVWKGKWNGTTEVAIKTLKQGTMSREDFLKEAKIMKRLHHPRLVRLYAVVTTEPIYIVTELMPNGSLLHYLRDGAGQDLGLRPLVDMMAQIASGMAYLEQEGYIHRDLAARNILVGEHNTVKVADFGLARIIDSGNETYTAKQGAQFPIKWTAPEAALLGRFTVKSDVWSFGIVIYEIVTHGQVPFPSMNNTETLQQVDSGYRMPRPANCPVSIYEVMLHAWDAIPENRPTFAFLCAYFEDYFANAERAYRPA 786

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BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A0V0J6V3 (Tyrosine-protein kinase OS=Schistocephalus solidus OX=70667 GN=TR116233 PE=3 SV=1)

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 261/470 (55.53%), Postives = 340/470 (72.34%), Query Frame = 1

Query:  469 TSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGY----VVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAA 1866
            +S   GS++   +NR L+AIFDY ART +EI L+KGD +++L  +D +WW VE   T  +GYVPSS++A E+S E+++WY P I+RKD+ER LL   N RG FLIR SETT+G   LSV D  V+S       V HY++K  + G  YITTK+ FP+L  L+ +YS   NGLCC L+ PC +P P+ +DLS +TKD WE+ R S+   E+LG+GQFGEVW+  WNGTT VAVK LKPGTM+ E+FLKEA++MK+  H  LVRLYA+C ++PI I+TELM  GSLL YLR   G+ + L+ L+D ++QIA+GMAYLE   Y+HRDLAARNILVGE    KIADFGLAR+++   E Y A +G++FP+KWTAPEAAL G+F+ KSDVWS+G+++YEIIT GQVP+PSM+N+E L  +  GYRMP P  CP  IY IMLQ W+   + RPTFA L D F+D F + E+ YR A
Sbjct:  199 SSNEQGSESPELKNR-LVAIFDYNARTDEEISLRKGDVMLVLNDSDSEWWFVEHCRTSAKGYVPSSYVAFEFSVEAEEWYVPKISRKDSERLLLLNSNNRGTFLIRESETTKGTLTLSVRDREVDSCLHTTDTVKHYRVKHIDGGGFYITTKRGFPTLRDLVEHYSADANGLCCRLTRPCPRPPPLTTDLSVQTKDHWEVPRKSISFVEQLGSGQFGEVWKATWNGTTEVAVKMLKPGTMSTEEFLKEARIMKAARHPRLVRLYAVCIEDPILIITELMPHGSLLHYLRDGPGKNLTLRPLVDMMAQIASGMAYLERERYIHRDLAARNILVGENCCVKIADFGLARMVEDRYETYVAQKGTKFPIKWTAPEAALMGRFTIKSDVWSYGIVLYEIITHGQVPYPSMNNTETLNQVGNGYRMPQPTTCPDPIYGIMLQTWDAVADKRPTFAYLCDFFEDYFASTETNYRHA 667

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BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: fyna (tyrosine-protein kinase fyna [Source:NCBI gene;Acc:103043249])

HSP 1 Score: 522.702 bits (1345), Expect = 7.129e-179
Identity = 244/452 (53.98%), Postives = 319/452 (70.58%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              +A++DY+ART D++  +KG++  +L S + DWW      TG  GY+PS+++A   S +++DWYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNGTT VAVKTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE M KGSLL +L+   G+ + L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP  ++E+MLQCW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   86 LFVALYDYEARTEDDLSFRKGEKFQILNSTEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSNGNPRGTFLIRESETTKGAYSLSIQDWDDIKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSARAAGLCCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGTTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMGKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQPGD 535

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BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: yrk (proto-oncogene tyrosine-protein kinase Yrk [Source:NCBI gene;Acc:103036565])

HSP 1 Score: 509.605 bits (1311), Expect = 9.407e-174
Identity = 240/452 (53.10%), Postives = 319/452 (70.58%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              IA++DY ART D++  +KG++  ++ + + DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL   N RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F ++ QL+++YS+   GLCC L   C +  P ++DLS KTKD WEI R SLQL +KLG GQFGEVW G+WNGTT VAVKTLKPGTM+ E FL EA++MK L H  LV+LYA+ S+EPIYI+TE MS+GSLL +L+   G+++ L QL+D  +QIA GMAY+E   Y+HRDL A NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+GKF+ KSDVWSFG+L+ E+IT+G+VP+P M+N E L+ +E GYRMP P+  P+ ++E+MLQCW    + R TF  L+   +D F   E  Y+  E
Sbjct:   86 LFIALYDYDARTEDDLTFQKGEKFHIINNTEGDWWEARSLDTGKSGYIPSNYVAPVDSIQAEEWYFGKMGRKDAERQLLGQNNPRGTFLIRESETTKGAYSLSIRDWDDAKGDHVKHYKIRKLDNGGYYITTRSQFETVQQLVVHYSDRAAGLCCRLIGSCRRGMPKLADLSVKTKDVWEIPRESLQLIKKLGNGQFGEVWMGMWNGTTKVAVKTLKPGTMSPEAFLDEAQIMKRLRHDKLVQLYAVVSEEPIYIITEFMSQGSLLDFLKDGEGRSLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVERGYRMPCPQGSPASLHELMLQCWRKDADERHTFEYLQGFLEDYFTATEPQYQPGE 535

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BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: SRC (proto-oncogene tyrosine-protein kinase Src-like [Source:NCBI gene;Acc:103042998])

HSP 1 Score: 501.516 bits (1290), Expect = 1.743e-170
Identity = 239/461 (51.84%), Postives = 318/461 (68.98%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR*LYYQK 1899
             +A++DY++RT  ++  KKG+R+ +L + + DWWL     TG  GY+PS+++A   S ++++W+F  ITR+D+ER LL   N RG FL+R SETT+GA CLSVLD+    G  + HYKI+K + G  YIT++  F SL QL+L+Y    +GLC  L+  C    P    L+   +D WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLK GTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MS+GSLL +L+ + G+ + L QL+D  SQIA GMAY+E   YVHRDL A NILVG+  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CPS ++E+ML CW   PE RPTF  L+   +D F + E  Y+        +Y QK
Sbjct:   89 FVALYDYESRTTADLTFKKGERLQILNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWFFGKITRRDSERLLLNIQNRRGTFLVRESETTKGAYCLSVLDYDNMKGLNIKHYKIRKLDSGGFYITSRTQFTSLQQLVLHYRTHADGLCHVLTDICPMLKPQTQGLA---RDAWEIPRESLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKRGTMSPEAFLEEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSQGSLLDFLKGDKGKFLRLPQLVDMASQIAAGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQVERGYRMPCPAECPSSMHELMLSCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQPENLFLYKIYSQK 544

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BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: clul1 (tyrosine-protein kinase yes [Source:NCBI gene;Acc:103029125])

HSP 1 Score: 494.197 bits (1271), Expect = 1.192e-167
Identity = 232/452 (51.33%), Postives = 312/452 (69.03%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            F +A++DY+ART D++  KKGDR  ++ + + DWW      TG +GY+PS+++A   S ++++WYF  + RKDAER LL PGN RG FL+R SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L +L+ +Y+   +GLC  L+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA++MK L H  LV LYA+ S+EPIYIVTE M KGSLL +L+   G+ + L QL+D  +QIA+GMA++E   Y+HRDL A NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M N E L+ +E GYRMP P+ CP  ++E+M  CW   P+ RPTF  ++   +D F   E  Y+  +
Sbjct:   99 FFVALYDYEARTSDDLSFKKGDRFQIINNTEGDWWEARSINTGKKGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLVPGNQRGTFLVRESETTKGAYSLSIRDWDDMKGDNVKHYKIRKLDNGGYYITTRAQFETLQKLVKHYTEHADGLCYRLTTVCPTVKPQTQGLA---KDAWEIPRESLRLELKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEYIQSFLEDYFTATEPQYQPGD 545

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BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: SRC (proto-oncogene tyrosine-protein kinase Src-like [Source:NCBI gene;Acc:103042998])

HSP 1 Score: 494.582 bits (1272), Expect = 7.182e-167
Identity = 237/456 (51.97%), Postives = 315/456 (69.08%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESN------DPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAA 1866
             +A++DY++RT  ++  KKG+R+ +L +       + DWWL     TG  GY+PS+++A   S ++++W+F  ITR+D+ER LL   N RG FL+R SETT+GA CLSVLD+    G  + HYKI+K + G  YIT++  F SL QL+L+Y    +GLC  L+  C    P    L+   +D WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLK GTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MS+GSLL +L+ + G+ + L QL+D  SQIA GMAY+E   YVHRDL A NILVG+  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  +E GYRMP P +CPS ++E+ML CW   PE RPTF  L+   +D F + E  Y+ A
Sbjct:   89 FVALYDYESRTTADLTFKKGERLQILNNTRKYNYREGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWFFGKITRRDSERLLLNIQNRRGTFLVRESETTKGAYCLSVLDYDNMKGLNIKHYKIRKLDSGGFYITSRTQFTSLQQLVLHYRTHADGLCHVLTDICPMLKPQTQGLA---RDAWEIPRESLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKRGTMSPEAFLEEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSQGSLLDFLKGDKGKFLRLPQLVDMASQIAAGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQVERGYRMPCPAECPSSMHELMLSCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQPA 539

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BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57])

HSP 1 Score: 494.197 bits (1271), Expect = 2.042e-169
Identity = 235/460 (51.09%), Postives = 315/460 (68.48%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESN--------DPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              +A++DY ART D++  +KG++  ++ +         + DWW     +TGN+GY+PS+++A   S ++++WYF  ++RKDAER LL PGN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L +L+ +YS   +GLC  L+  C    P    L+   +D WE+ R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+ + L QL+D  +QIA GMAY+E   Y+HRDL A NILVG+  ICKIADFGLARLI+     Y A QG++FP+KWTAPEAA++G+F+ KSDVWSFG+L+ E++T+G+VP+P M N E L+ +E GYRMP P  CP  ++E+M+QCW   PE RPTF  L+   +D F   E  Y+  E
Sbjct:   17 LFVALYDYDARTQDDLSFRKGEKFQIINNTIEVAVVYREGDWWEARSLSTGNKGYIPSNYVAPADSVQAEEWYFGKVSRKDAERQLLCPGNPRGTFLIRESETTKGAYSLSIRDWDEVKGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVQHYSEHADGLCYKLTLVCPNEKPQTQGLA---RDAWEMPRDSLKLELKLGQGCFGEVWAGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARLIEDN--EYTARQGAKFPIKWTAPEAAMFGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPPSCPESLHELMMQCWKKDPEERPTFEYLQAFLEDYFTATEPQYQPGE 471

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BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72])

HSP 1 Score: 461.07 bits (1185), Expect = 8.495e-157
Identity = 214/449 (47.66%), Postives = 305/449 (67.93%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYR 1860
             ++A++D++    D++  KKGD++ +++    +WW+ E     ++GY+PS+++A   S E+++W+F  ++RK+ ER LL PGN+ G +L+R SE+ +G+  LSV D+ + +G VV HYKI+  + G  +I+ +  FP L  LI +Y+   +GLC  L  PC    P         KD WEI R SL+LS++LGAGQFGEVW G++N  T VA+KT+KPG+M+ E FL EA +MK+L H  LVRLYA+ + EPIYIVTE M  GSLL YL+S  G  + + ++ID  +QIA GMA++E   Y+HRDL A NILV E    KIADFGLAR+I+     Y A +G++FP+KWTAPEA  +G FS KSDVWSFG+L+ EIIT G++P+P MSNS+ ++ +E GYRMP P+Q P  +Y +M+ CW  RPE RPTF  L+ V +D F + E  Y+
Sbjct:    2 LVVALYDFEQLNPDDMGFKKGDKMRIIQERG-EWWMAELMDGSHKGYIPSNYVAKANSLETEEWFFSGVSRKEGERLLLAPGNSIGAYLLRDSESNKGSYSLSVRDYDITNGDVVRHYKIRTLDNGGYFISARLTFPDLFALIQHYTAHSDGLCQKLLRPCVSKKP----QQLWEKDAWEIPRDSLKLSKRLGAGQFGEVWMGIYNNRTKVAIKTMKPGSMSPEAFLDEANLMKTLQHPRLVRLYAVVTQEPIYIVTEFMENGSLLDYLKSTEGSTLPMPKMIDMAAQIAEGMAFIERKNYIHRDLRAANILVNEQLASKIADFGLARIIEDN--EYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEIITFGRIPYPGMSNSDVIRQLERGYRMPCPEQAPKQLYGVMMDCWKERPEERPTFEYLQGVLEDFFTSTEGQYQ 443

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BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7])

HSP 1 Score: 458.373 bits (1178), Expect = 1.128e-155
Identity = 224/452 (49.56%), Postives = 309/452 (68.36%), Query Frame = 1

Query:  520 IAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQR--ATGN-----RGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQ-GAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPC---SKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCE-MYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLR---DVFD 1827
            +A++DY  RT +++  K+G+ + + +  + DWW  +++  +T N     RGY+P++++A   S +++ W+F  I R DAE+ LL   N  G FLIR SE+ +    LSV D     G  V HY+I++ ++ G  +I+ +  F +L +L+ YY +  +GLC +L  PC     PT I   LSY T DKWEI R+S+QL ++LGAG FGEVW+GLWN +T VAVKTLKPG M KE+F+ EA++MK L H NL++LYA+CS +EPIYI+TELM  GSLL YLR   G+ +   +L+D   QIA GMAYLE+  Y+HRDLAARNILVGEG++CK+ADFGLAR+I    E  YE   G++ P+KWTAPEA  + +FS KSDVWSFG+L+YE+IT G++P+P M N E L+ ++ GYRMP P  CP   Y IML+CWN + E RPTF +L+   D FD
Sbjct:    2 VALYDYDGRTNEDLSFKEGELLEVTDKTNSDWWYAQKKTASTSNERYNTRGYIPANYVAEYQSLDAEPWFFGDIKRADAEKYLLADVNTTGAFLIRQSESRKTDYSLSVRD-----GSTVKHYRIRQLDENGGFFISRRVTFQNLIELVQYYKSNSDGLCMALQKPCVVIEAPTTI--GLSYNTVDKWEIPRASIQLQKRLGAGMFGEVWQGLWNNSTLVAVKTLKPGAMKKEEFIGEAQIMKQLRHANLIQLYAVCSQEEPIYIITELMRHGSLLDYLRGPLGKQLKAPELVDMARQIAAGMAYLESQNYIHRDLAARNILVGEGKVCKVADFGLARIIKVRYEDEYEGKAGAKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELITYGRMPYPEMGNMEVLKQLDRGYRMPQPDNCPPLFYSIMLECWNKKEEERPTFETLQWRLDYFD 446

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BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72])

HSP 1 Score: 452.595 bits (1163), Expect = 1.411e-152
Identity = 210/449 (46.77%), Postives = 302/449 (67.26%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYR 1860
             ++A++DY     D++  ++GD+++++E  + DWW     AT   GY+PS+F+A   S E ++W+F  ++RKDAER LL  GN  G +LIR SET +G+  LSV DH V  G  V HYKI+  ++G  +IT++  F +L +L++YY    +GLC  L  PC    P         KD WEI R S++L +KLGAGQFG+VW G++N  T VAVK +KPG+M  + FL+EA +MK+L H  LVRL+A+ +DEPI+IVTE M KGSLL +L++  G  +   ++ID  +Q+A GMA++E+  Y+HRDL A NILV    +CKIADFGLAR+I+     Y A +G++FP+KWTAPEA  +G FS KSDVWSFG+L+ E++T G++P+P M+N E ++++E GYRMP P  CP  +Y IM +CW  +PE RPTF  L+ + +D +   E  Y+
Sbjct:   67 LVVALYDYDPIHADDLCFRRGDQLVIVEEGN-DWWKARSVATKKEGYIPSNFVAKVNSIEKEEWFFKGLSRKDAERQLLLCGNKIGSYLIRDSETNKGSYSLSVRDHIVEVGDTVKHYKIRTLDKGGYFITSRITFHTLQELVVYYHLKADGLCQKLGKPCIAIQP----QKPWEKDAWEIPRESIKLEKKLGAGQFGDVWMGVYNKKTKVAVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRLHAVVTDEPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDN--EYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDNCPCELYSIMQECWRQKPEERPTFEYLQSLLEDFYTATELQYQ 508

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BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006670.1 (pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene:ENSPMAG00000006016.1 transcript:ENSPMAT00000006670.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 414.075 bits (1063), Expect = 1.742e-139
Identity = 200/381 (52.49%), Postives = 265/381 (69.55%), Query Frame = 1

Query:  745 LLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPC-SKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCE-MYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECIS 1878
            L++ GN  G FL+R SET+     LSV D     G  V HYKI+   +G+ +IT +  F +L  L+  YS   NGLC +L+ PC  K  P    LS    DKWEI RSS+QL ++LGAGQFGEVW+GLWN TTPVA+KTLK GTM ++DFL+EA++MK L H  L++LYA+C+ +EPIYI+TELMS GSL  YL++  G+++ L +L+D  +Q+A GMAYLE   Y+HRDLAARNILV E   CK+ADFGLAR+I    E  YEA  GS+FP+KWTAPEAA + +FS KSDVWSFGVL++EIIT G++P+P  +N+E L  ++ GYRMP P  CP   Y++ML+CWN+  + RPTF +L+   +D F    + Y  A  ++
Sbjct:   10 LMKSGNVHGSFLVRQSETSGHGYSLSVRD-----GDTVKHYKIRVLEKGSFFITRRNQFATLRDLVQSYSRDANGLCVTLNQPCLKKEMPQTEGLSSDMADKWEIPRSSVQLVKRLGAGQFGEVWQGLWNKTTPVAIKTLKQGTMDRDDFLREAQLMKRLRHPKLIQLYAVCTQEEPIYIITELMSNGSLANYLQTPEGRSLDLVELVDMAAQVAAGMAYLEAQNYIHRDLAARNILVAEHNACKVADFGLARVIKMSNEDEYEARVGSKFPIKWTAPEAANYNRFSIKSDVWSFGVLLHEIITYGKLPYPGQTNAEVLAAVDRGYRMPCPPGCPQAFYDLMLECWNVDDQARPTFETLQWQLEDFFSQEGTNYTEAGALN 385

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BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 92.8189 bits (229), Expect = 7.564e-20
Identity = 65/247 (26.32%), Postives = 120/247 (48.58%), Query Frame = 1

Query: 1072 QLSEKLGAGQFGEVWRGLWNGTTPV-AVK-TLKPGTMTKEDFLKEAKVMKSLCHINLVRLYA-ICSDEPIYIVTELMSKGSLLQYL-RSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPT 1800
             L + +G G +G V++ +   T  V A+K  +        D + E  ++K+L H N+V+ +  I     +YI+ E  + GSL + + RS TG +    +   +++Q   G+ YL   G +HRD+ A NIL+      K+ADFG++ ++++       +      + W APE       ST SD+WS G  + E++T+   P+ +++++     +E     P P      + + + +C+      RPT
Sbjct:   26 HLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSE--NESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGT------LNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNP-PYHNLTDANIYYAVENDTYYP-PSSFSEPLKDFLSKCFVKNMYKRPT 262

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BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952])

HSP 1 Score: 88.9669 bits (219), Expect = 8.963e-20
Identity = 73/238 (30.67%), Postives = 120/238 (50.42%), Query Frame = 1

Query: 1063 SSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKED-----FLKEAKVMKSLCHINLVRLY-AICSDEPIYIVTELMSKGSLLQYLRSET----GQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGK-FSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPS 1743
            S  +  EKLG G +  V++GL N TT V V  LK   +  E+      ++E  +MK L H N+VRLY  I ++  + +V E M    L +Y+ S T     + + L  +  F  Q+  G+A+   +  +HRDL  +N+L+ +    K+ DFGLAR        + +   + +   + AP+  +  + +ST  D+WS G ++ E+IT G+  FP  ++ E L+ I      P+    PS
Sbjct:    5 SQFKQLEKLGNGTYATVYKGL-NKTTGVYV-ALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMD-NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLW---YRAPDVLMGSRTYSTSIDIWSCGCILAEMIT-GKPLFPGTNDEEQLKLIFDIMGTPNESLWPS 235

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BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103])

HSP 1 Score: 89.3521 bits (220), Expect = 2.469e-19
Identity = 74/203 (36.45%), Postives = 105/203 (51.72%), Query Frame = 1

Query: 1087 LGAGQFGEVWRGLWNGTT-PVAVK-TLKP---GTMTKEDFLKEAKVMKSLCHINLVRLYAICSD--EPIYIVTELMSKGSLLQYLRSETGQAMILKQLID-FISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAAL-WGKFSTKSDVWSFGVLIYEIITRGQVPFP 1668
            +G G FG V       T+ PVA+K  +KP     + K  + +E K++K L H NL+ L  I     E IY VTEL  +G+ L  L        + KQ +  F+ QI  G+ Y+ ++G +HRDL   NIL+ E    KI DFGLAR+ D     Y +++  R      APE  L W K+  + D+WS G +  E+I  G+  FP
Sbjct:   29 VGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTY-RELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL--QGTDLHRLLQTRP---LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYR------APEIMLTWQKYDVEVDIWSAGCIFAEMI-EGKPLFP 218

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BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 89.3521 bits (220), Expect = 9.891e-19
Identity = 79/264 (29.92%), Postives = 127/264 (48.11%), Query Frame = 1

Query: 1081 EKLGAGQFGEVWRGLWNGTTP--VAVKTLKPGT---------MTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIY-IVTELMSKGSLLQYLRSETG-QAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGS-RFPVKWTAPEAALWGK-FSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPS-PKQCPSYIYEI----MLQCWNLRPEHRPTFASL 1812
            E +G G FG V+  L N TT   +AVK ++             T E    E   +K L H+N+V+     +   IY +  E ++ GS+   +R        ++K L    +Q+  G+AYL + G +HRD+ A N+L+ +  ICKI+DFG++R      ++Y  S  + R  V W APE     + +S K D+WS G ++ E+   G+ P+ ++    A+  I      P  P+     I +I    +  C+ + PE RPT   L
Sbjct: 1179 EMIGKGSFGAVYLCL-NVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLT---TQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISR---KSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANEL 1434

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BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: GIN4 (Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915])

HSP 1 Score: 86.2705 bits (212), Expect = 8.977e-18
Identity = 84/268 (31.34%), Postives = 126/268 (47.01%), Query Frame = 1

Query: 1072 QLSEKLGAGQFGEVWRGLWNGTT--PVAVKTLKPGTM-------------TKEDFL-----KEAKVMKSLCHINLVRLYAI-CSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAAL---WGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNS--EALQNIETG-YRMPSPKQCPSYIYEIMLQCWNLRPEHR 1794
            +L E LG G  G+V     NG+T    AVK +                  T  D L     +E  +MK L H N++RLY +  ++  +Y+V E   KG L   L  E G  +   + I F  QI  G++Y    G VHRDL   N+L+      KIADFG+A L   G ++ E S GS     + APE      +  F+  SDVWS GV+++ ++T G++PF     +    L  ++ G + MPS  +      +++ +   + PE R
Sbjct:   20 KLGETLGLGSTGKVQLA-RNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLL-VERG-PLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEG-KLLETSCGSPH---YAAPEIVSGIPYQGFA--SDVWSCGVILFALLT-GRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERR 277

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BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO47195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN18])

HSP 1 Score: 267.314 bits (682), Expect = 5.785e-84
Identity = 124/267 (46.44%), Postives = 177/267 (66.29%), Query Frame = 1

Query: 1042 DKWEIDRSSLQLSEKLGAGQFGEVWRGLWNG-TTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEP-IYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLF 1836
            D+WEI+R+ + +  KLG GQ+GEV+ G W      VAVKTL+  TM  E+FLKEA VMK + H NLV+L  +C+ EP  YI+TE M  G+LL YLRS  G+ +    L+   +Q+ + M+YLE+  ++HRDLAARN LVG+  + K+ADFGL+RL+    ++Y A QG++FP+KWTAPEA     FS KSDVW+FG+L++E+ T G  P+P +  S+    ++ GYRMP P+ CP  +Y +M  CW   P  RP+F  + +  + +F
Sbjct:    5 DEWEIERTEIAMKHKLGGGQYGEVYEGTWKKYNKTVAVKTLREETMEVEEFLKEASVMKGIKHQNLVQLLGVCTREPPFYIITEFMMNGNLLDYLRSPKGKDLDAVTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGDNNLVKVADFGLSRLVSE--DIYTAHQGAKFPIKWTAPEALAHNTFSIKSDVWAFGILLWELATYGMSPYPGIDLSQVYDKLDGGYRMPCPEGCPPEVYSLMQTCWCWDPNSRPSFKEIHEKLNTMF 269

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BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO49804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFY7])

HSP 1 Score: 239.58 bits (610), Expect = 2.436e-74
Identity = 109/219 (49.77%), Postives = 155/219 (70.78%), Query Frame = 1

Query: 1123 LWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLAR-LIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWN 1776
            +W GT PVAVK +K G M++EDF++EAKVMK   H NLV+LY ICS++PIYI+ ELM  G LL YLR    + +   ++ + + Q+A  M YLE+  ++HRDLAARN L+GE    K+ADFGLAR +ID   + Y AS+G++FP+KW APE  L+ KFS+KSDVW+FG+L +E+ T G+ P+P+ +N++ +Q +  GYR+  P +CP   Y  M +CW+
Sbjct:    1 MWRGTIPVAVKMMKDGAMSEEDFIEEAKVMKQFQHGNLVQLYGICSEKPIYIIQELMKGGCLLHYLRKSQFK-LQSAEMTEMVRQVAAAMKYLESHNFIHRDLAARNCLIGENRTVKVADFGLARYVID---DEYTASEGTKFPIKWAAPEVILYSKFSSKSDVWAFGILAWEVYTGGKQPYPATNNTDVVQMVINGYRLEKPLRCPDAAYSTMRKCWH 215

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BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO40994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5K8])

HSP 1 Score: 230.72 bits (587), Expect = 1.686e-68
Identity = 122/273 (44.69%), Postives = 170/273 (62.27%), Query Frame = 1

Query: 1051 EIDRSSLQLSEKLGAGQFGEVWRGLWN----GTTPVAVKTLKPGTMTKE--DFLKEAKVMKSLCHINLVRLYAICSD-EPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAE 1848
            E+D+  L+L + +G G+FG+V++G        T PVA+KTLK G+ +K   DFL EA VM   C  N++ L  + S   P+ IVTE MS GSL  +L+ +    + L QL+     IA+GM YL    +VHRDLAARNILV E  +CK+ADFGL+R ++     YE S G + PV+WTAPEA  + KFST SDVWS+G+L++E  +  + P+   SN E +  +ETGYR+P P  CP  I++IML+CW+     RP+FA +    D L  + E
Sbjct:   52 ELDKRWLKLEKVIGGGEFGDVYKGTLKRPGENTIPVAIKTLKQGSTSKNRGDFLSEASVMGQFCDPNVIFLEGVVSKTHPLMIVTEFMSNGSLDNFLK-KMDSKLSLIQLMGMARGIASGMKYLSEMNFVHRDLAARNILVTETLVCKVADFGLSRELEDSA--YETS-GGKIPVRWTAPEAIKYRKFSTSSDVWSYGILLWETFSFAERPYWDWSNFEVMDRVETGYRLPPPMSCPKVIHQIMLECWDADRTKRPSFALIVKQLDSLIRSPE 320

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BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO49315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA0])

HSP 1 Score: 218.394 bits (555), Expect = 8.429e-65
Identity = 123/294 (41.84%), Postives = 168/294 (57.14%), Query Frame = 1

Query: 1015 ISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWR----GLWNGT--TPVAVKTLKPGTMTKE--DFLKEAKVMKSLC-HINLVRLYAICSDE-PIYIVTELMSKGSLLQYLRS-----------ETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDL 1833
            ++++  +  ++WE DR+ L + E LG G FG+V R    GL   +  T VAVK LK     +E  D + E +VMKS+  HIN++ L   C+   P++++ E    G+L Q+LR            E  + + L  L+ F  QIA GM YL +   +HRDLAARNILV +  I KIADFGLAR +    + Y  +   R PVKW A EA     ++T+SDVWSFG++++EIIT G  P+P +   +    + TGYRM  P  C   +YEIM  CWN  PE RPTF SL   FDDL
Sbjct:   41 LNEVEIEYDEEWEFDRTYLVIREVLGEGAFGKVMRAEAFGLHGNSACTTVAVKMLKEDATEQELFDLVSEMEVMKSIGKHINIINLLGTCTQHGPLFVLVEYARWGNLRQFLRDRRPVKDYDDVMEPAETLTLLNLMTFCYQIAKGMEYLASRKCIHRDLAARNILVADDNILKIADFGLARDVH-NVDYYRKTTDGRLPVKWMAFEALFDRVYTTQSDVWSFGIVVWEIITFGGTPYPGVPIEKLCMLLNTGYRMERPVNCSKELYEIMRNCWNENPEARPTFTSLVQAFDDL 333

[Close]

BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO33736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRD7])

HSP 1 Score: 218.394 bits (555), Expect = 3.529e-64
Identity = 110/272 (40.44%), Postives = 167/272 (61.40%), Query Frame = 1

Query: 1051 EIDRSSLQLSEKLGAGQFGEVWRGLWNGTTP----VAVKTLKPGTMTK--EDFLKEAKVMKSLCHINLVRLYAICS-DEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEA---SQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLF 1836
            EI++  L+L   +G G+F +V+RG+          VAVK LKPG+  K  EDF  EA +M    H N++ L  + +   P+ I+TE +  GSL  +L+S  G+   L QL+     +A GMAYL    ++HRDLAARNILV +    K++DFGL+R +D   E  ++   +QG + PV+WTAPEA  + KFS+ SDVWS+G+L++EI++ G+ P+ +  N + +  +E GYR+P+P +CP  I+ +ML CW+     RP FA +   FD++ 
Sbjct:   21 EINKDDLKLEIIIGGGEFADVYRGVLTNEDKTQEKVAVKILKPGSSHKNREDFCVEASIMGQFDHPNVIALKGVITRTRPMMIITEFLENGSLDNFLKSNDGRLTTL-QLVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSRELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVMDRVEGGYRLPAPMKCPKVIHNLMLDCWDKEKTSRPKFADIVRRFDEVI 291

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BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: fyna (tyrosine-protein kinase fyna [Source:NCBI gene;Acc:101157019])

HSP 1 Score: 533.102 bits (1372), Expect = 0.000e+0
Identity = 248/452 (54.87%), Postives = 323/452 (71.46%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              +A++DY+ART D++  +KG+R  +L S + DWW      TG  GY+PS+++A   S +++DWYF  + RKDAER LL  GNARG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L QL+ +YS    GLCC L  PC K  P ++DLS KTKD WEI R SLQL ++LG GQFGEVW G WNGTT VAVKTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYIVTE MSKGSLL +L+   G+ + L  L+D  +Q+A GMAY+E   Y+HRDL + NILVG+G +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+GKF+ KSDVWSFG+L+ E++T+G+VP+P M+N E L+ +E GYRMP P+ CP+ ++E+M+QCW   PE RPTF  L+   +D F   E  Y+  +
Sbjct:   86 LFVALYDYEARTEDDLSFRKGERFQILNSTEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSSGNARGTFLIRESETTKGAYSLSIQDWDDIKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSARAAGLCCRLIAPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGTTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDGLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPTSLHELMVQCWKKDPEERPTFEYLQAFLEDYFTATEPQYQPGD 535

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BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: yrk (proto-oncogene tyrosine-protein kinase Yrk [Source:NCBI gene;Acc:101155365])

HSP 1 Score: 513.842 bits (1322), Expect = 1.382e-175
Identity = 241/452 (53.32%), Postives = 318/452 (70.35%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
              IA++DY ART D++  +KG++  ++ + + DWW      TG  GY+PS+++A   S ++++WYF  + RKDAER LL  GN RG FLIR SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F ++ QL+ +Y+    GLCC L   C +  P ++DLS KTKD WEI R SLQL +KLG GQFGEVW G+WNGTT VAVKTLKPGTM+ E FL+EA++MK L H  LV+LYA+ S+EPIYI+TE MS+GSLL +L+   GQ + L QL+D  +QIA GMAY+E   Y+HRDL A NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+IT+G+VP+P M+N E L+ +E GYRMP    CP+ ++E+MLQCW   P+ R TF  L+   +D F   E  Y+  E
Sbjct:   78 LFIALYDYDARTEDDLTFQKGEKFQIINNTEGDWWEARSLDTGKSGYIPSNYVAPIDSIQAEEWYFGKMGRKDAERQLLGQGNPRGTFLIRESETTKGAYSLSIRDWDDTKGDHVKHYKIRKLDNGGYYITTRSQFDTVQQLVEHYTERAAGLCCRLIGSCKRGMPKLADLSVKTKDMWEIPRESLQLIKKLGNGQFGEVWMGMWNGTTKVAVKTLKPGTMSPEAFLEEAQIMKRLRHDKLVQLYAVVSEEPIYIITEFMSEGSLLDFLKDGEGQTLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVERGYRMPCAPGCPASLHELMLQCWRREPDERHTFEYLQSFLEDYFTATEPQYQPGE 527

[Close]

BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:NCBI gene;Acc:101173856])

HSP 1 Score: 509.605 bits (1311), Expect = 1.039e-173
Identity = 239/451 (52.99%), Postives = 317/451 (70.29%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  +KGDR+ ++ + + DWWL     TG  GY+PS+++A   S ++++WYF  ITR+D+ER LL   N RG FL+R SETT+GA CLSVLD+    G  V HYKI+K + G  YIT++  F SL QL+ +Y    +GLC +L+  C    P    L+   +D WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MS+GSLL +L+ +TG+ + L QL+D  +QIA GMAY+E   YVHRDL A NILVG+  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFGVL+ E+ T+G+VP+P M N E L  +E GYRMP P +CPS ++E+ML CW   PE RPTF  L+   +D F + E  Y+  E
Sbjct:   97 FVALYDYESRTASDLTFRKGDRLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLQNRRGTFLVRESETTKGAYCLSVLDYDNAKGLNVKHYKIRKLDSGGFYITSRTQFTSLQQLVFHYRKHSDGLCHALTDVCPVAKPQTQGLA---RDAWEIPRESLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSQGSLLDFLKGDTGKLLRLPQLVDMAAQIAAGMAYVEKMNYVHRDLRAANILVGDNLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQVERGYRMPCPAECPSSLHELMLSCWRKDPEERPTFEYLQGFLEDYFTSTEPQYQPGE 542

[Close]

BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:101164480])

HSP 1 Score: 496.508 bits (1277), Expect = 9.011e-169
Identity = 236/451 (52.33%), Postives = 313/451 (69.40%), Query Frame = 1

Query:  517 LIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
             +A++DY++RT  ++  +KG+R+ ++ + + DWWL    ATG  GY+PS+++A   S ++++WYF  ITR+D+ER LL   N RG FL+R SETT+GA CLSVLD+    G  V HYKI+K + G  YIT++  F  L QL  Y+    +GLC SL+  C    P    L+   KD WEI R SL+L  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA+VMK L H  LV+LYA+ S+EPIYIVTE MS+GSLL +L+ + G+ + L QL+D  SQIA+GMAY+E   YVHRDL A NILVG+  +CK+ADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E+ T+G+VP+P M N E L  ++ GYRMP P  CP  ++E+ML CW    E RPTF  L+   +D F + E  Y+  E
Sbjct:   89 FVALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLATGESGYIPSNYVAPSESIQAEEWYFGKITRRDSERLLLSLENRRGTFLVRESETTKGAYCLSVLDYDNTKGLNVKHYKIRKLDSGGFYITSRTQFSGL-QLSRYFPAHADGLCHSLTDICPVLKPQTQGLA---KDAWEIPRESLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQVDRGYRMPCPADCPESLHELMLTCWRKEAEERPTFEYLQSFLEDYFTSTEPQYQPGE 533

[Close]

BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: YES1 (YES proto-oncogene 1, Src family tyrosine kinase [Source:NCBI gene;Acc:101158313])

HSP 1 Score: 496.893 bits (1278), Expect = 1.041e-168
Identity = 233/452 (51.55%), Postives = 313/452 (69.25%), Query Frame = 1

Query:  514 FLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAE 1869
            F +A++DY+ART D++  KKGDR  ++ + + DWW      TG +GY+PS+++A   S ++++WYF  + RKDAER LL PGN RG FL+R SETT+GA  LS+ D     G  V HYKI+K + G  YITT+  F +L +L+ +Y+   +GLC  L+  C    P    L+   KD WEI R SLQL  KLG G FGEVW G WNGTT VA+KTLKPGTM+ E FL+EA++MK L H  LV L+A+ S+EPIYIVTE MSKGSLL +L+   G+ + L  L+D  ++IA+GMA++E   Y+HRDL A NILVG+  +CKIADFGLARLI+     Y A QG++FP+KWTAPEAAL+G+F+ KSDVWSFG+L+ E++T+G+VP+P M N E L+ +E GYRMP P+ CP  ++E+M  CW   P+ RPTF  L+   +D F + E  Y+  E
Sbjct:  102 FFVALYDYEARTSDDLTFKKGDRFQIINNTEGDWWEARSITTGKKGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNDRGTFLVRESETTKGAYSLSIRDWDSAKGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHRLTTVCPTVKPQTQGLA---KDAWEISRESLQLELKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLFAVVSEEPIYIVTEYMSKGSLLDFLKEGEGKFLNLVMLVDMAAKIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIED--NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMKLCWKKEPDERPTFEYLQSFLEDYFTSTEPQYQPGE 548

[Close]

BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000020289.1 (SMESG000020289.1)

HSP 1 Score: 1244.18 bits (3218), Expect = 0.000e+0
Identity = 609/609 (100.00%), Postives = 609/609 (100.00%), Query Frame = 1

Query:   55 MGNCVDKLENGSLRDNKYLPNQKENIDKDDYKFSNENSNQTQSYPSTPHMTKANVSSSSSVPIEKKYSISSFANSNVSKLTNSQEGSHMSVKISESCTTFINNSGENILPRLSDCSDRNWNVRXXXXXXXXXXXXLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR 1881
            MGNCVDKLENGSLRDNKYLPNQKENIDKDDYKFSNENSNQTQSYPSTPHMTKANVSSSSSVPIEKKYSISSFANSNVSKLTNSQEGSHMSVKISESCTTFINNSGENILPRLSDCSDRNWNVRSDSPSRHSQSSSLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR
Sbjct:    1 MGNCVDKLENGSLRDNKYLPNQKENIDKDDYKFSNENSNQTQSYPSTPHMTKANVSSSSSVPIEKKYSISSFANSNVSKLTNSQEGSHMSVKISESCTTFINNSGENILPRLSDCSDRNWNVRSDSPSRHSQSSSLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR 609

[Close]

BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000020289.1 (SMESG000020289.1)

HSP 1 Score: 1186.4 bits (3068), Expect = 0.000e+0
Identity = 588/609 (96.55%), Postives = 588/609 (96.55%), Query Frame = 1

Query:   55 MGNCVDKLENGSLRDNKYLPNQKENIDKDDYKFSNENSNQTQSYPSTPHMTKANVSSSSSVPIEKKYSISSFANSNVSKLTNSQEGSHMSVKISESCTTFINNSGENILPRLSDCSDRNWNVRXXXXXXXXXXXXLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR 1881
            MGNCVDKLENGSLRDNKYLPNQKENIDKDDYKFSNENSNQTQSYPSTPHMTKANVSSSSSVPIEKKYSISSFANSNVSKLTNSQEGSHMSVKISES                     RNWNVRSDSPSRHSQSSSLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR
Sbjct:    1 MGNCVDKLENGSLRDNKYLPNQKENIDKDDYKFSNENSNQTQSYPSTPHMTKANVSSSSSVPIEKKYSISSFANSNVSKLTNSQEGSHMSVKISESY--------------------RNWNVRSDSPSRHSQSSSLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR 589

[Close]

BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000020289.1 (SMESG000020289.1)

HSP 1 Score: 1066.22 bits (2756), Expect = 0.000e+0
Identity = 521/521 (100.00%), Postives = 521/521 (100.00%), Query Frame = 1

Query:  319 MSVKISESCTTFINNSGENILPRLSDCSDRNWNVRXXXXXXXXXXXXLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR 1881
            MSVKISESCTTFINNSGENILPRLSDCSDRNWNVRSDSPSRHSQSSSLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR
Sbjct:    1 MSVKISESCTTFINNSGENILPRLSDCSDRNWNVRSDSPSRHSQSSSLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAAECISR 521

[Close]

BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000003807.1 (SMESG000003807.1)

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 261/458 (56.99%), Postives = 344/458 (75.11%), Query Frame = 1

Query:  493 TDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAA 1866
            T+I + R LIA+FDY  RT +E+ L+KGDRV LL   DP+WWLVE   T ++GY+PSSF+A+E S ESQDW+   I+RKD+ER L+   N +G FL+R SET+QG   LSV D+  N    V HYKI+  +   V ITTK +F SL +LI +YS   NGLCC L+ PC +P P+ +DLS+KTKD+WEI RSS++L  KLGAGQFGEVW+G WN +T VAVKTLK G MT ++FLKEA++MK+L H  LV+LYA+C+D+PIYIVTELM+ GSLL YLR   G+ + +K L+D ++QIA GMA+LE   Y+HRDLAARNILVGE  +CK+ADFGLAR+I      YEA +G++FP+KWTAPEAA+ G+F+ KSDVWS+G+++YEI+T+G+VP+PSM+N+E LQ +E GYRMP P +CP  IY IML  W   P+ RPTF  L + F++ ++ AE+ Y+ A
Sbjct:  186 TEIEK-RVLIAMFDYNERTNEELSLRKGDRVYLLNEFDPEWWLVEHATTLDKGYIPSSFVALEGSLESQDWFISKISRKDSERLLMLQCNTQGTFLVRQSETSQGFLSLSVRDNEPNGSESVKHYKIRYADD-MVCITTKCMFSSLVELIDFYSKDSNGLCCRLTRPCPRPAPVTTDLSFKTKDQWEIPRSSIELVTKLGAGQFGEVWKGKWNNSTWVAVKTLKQGAMTTDEFLKEARIMKNLNHAKLVKLYAVCTDDPIYIVTELMTHGSLLAYLREGPGKNLEMKMLVDLMAQIACGMAFLEKERYIHRDLAARNILVGENNMCKVADFGLARMIRENSGTYEAKEGTKFPIKWTAPEAAMIGRFTIKSDVWSYGIVLYEIVTKGKVPYPSMNNTETLQEVEKGYRMPIPAECPHKIYNIMLTTWQQNPDDRPTFEFLCEFFENYYVHAETNYKHA 641

[Close]

BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000016930.1 (SMESG000016930.1)

HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0
Identity = 285/579 (49.22%), Postives = 384/579 (66.32%), Query Frame = 1

Query:  172 QTQSYPSTPHMTKAN--------VSSSSSVPIEKKYS-ISSFANSNVSKLTNSQEGSHMSVKISESCTTFINNSGENILPRLSDCSDRNWNVRXXXXXXXXXXXXLFTTSTNYGSKTDIHRNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGYVPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIKK-----TNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAICSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESGYRAA 1866
            +  SYP+TP  +  N        V+S + V +   +S  SS   S ++   NSQ   H  V+           S EN L +L    D    + S   +      ++    + Y  +TD+      +A+FDY AR  +EI ++K D + +++ +D DWW VE    G +GY+P S++A + S E++DW+F  I+RKD+ER LL  GN +G FLIR SET      LSV     N    VNHY+++K     + +    IT++K+F +L +L+ +YS   NGLCC L+  C +P P+ISDLS  T+D+WEI+R+S++L +KLG+G FGEV++G+WN TT VAVKTLKPGTM KE+FLKEA++MK L H NLVRLYA+CSDEPIYIVTELM+KGSLL+YLR E G+   LK+L+D +SQIANGMAYLE  GY+HRDLAARNIL+GE  ICKIADFGL R+I    + Y A QG++FP+KWTAPEAAL GKF+ KSDVWS+G+++YEIIT GQ PFP+M+N++ LQ +E GYRMP P  CP  +Y++ML CW   PE+RPTF  L + FDD F +AE  Y+ A
Sbjct:   71 KNHSYPNTPKSSSNNLIAHPNSIVASPNEVILSLSFSNCSSPLTSTINSKANSQTTRHSFVE-----------SSENYLKKLRQFPDPLNQINSAYLTSVMGPENV---QSFYSVETDV-----FVALFDYNARDEEEISIRKADYLKVIDDSDLDWWFVEHIGHGVKGYIPKSYIASKGSVEAEDWFFYNISRKDSERLLLLKGNIQGTFLIRGSETMPDQLSLSV-----NYNGTVNHYRVRKRRFPESMEEGFCITSRKMFFALPELVDFYSTEANGLCCKLTRACPRPPPVISDLSRNTRDRWEINRNSIELLKKLGSGNFGEVYQGIWNKTTDVAVKTLKPGTMAKEEFLKEARIMKRLNHSNLVRLYAVCSDEPIYIVTELMTKGSLLEYLREE-GKHTELKELMDMMSQIANGMAYLEKEGYIHRDLAARNILIGENNICKIADFGLTRVIQGSSDTYNARQGAKFPIKWTAPEAALMGKFTVKSDVWSYGIVLYEIITHGQTPFPAMNNTQTLQQVEKGYRMPKPSNCPQELYKVMLYCWEALPENRPTFKYLSEFFDD-FSSAECSYKPA 623

The following BLAST results are available for this feature:

BLAST of Tyrosine-protein kinase vs. Ensembl Human
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
BLAST of Tyrosine-protein kinase vs. TrEMBL
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
BLAST of Tyrosine-protein kinase vs. Planmine SMEST

BLAST of Tyrosine-protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
FYN	3.663e-178	52.54	FYN proto-oncogene, Src family tyrosine kinase [So...	[more]
FYN	3.663e-178	52.54	FYN proto-oncogene, Src family tyrosine kinase [So...	[more]
SRC	7.203e-173	53.22	SRC proto-oncogene, non-receptor tyrosine kinase [...	[more]
SRC	7.203e-173	53.22	SRC proto-oncogene, non-receptor tyrosine kinase [...	[more]
SRC	7.203e-173	53.22	SRC proto-oncogene, non-receptor tyrosine kinase [...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
src-1	2.475e-153	48.35	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]
src-1	5.441e-153	48.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]
src-1	5.441e-153	48.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]
src-1	9.862e-153	48.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]
src-1	9.862e-153	48.46	Tyrosine protein-kinase src-1 [Source:UniProtKB/S...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Src42A	3.595e-164	49.78	gene:FBgn0264959 transcript:FBtr0335275	[more]
Src64B	7.354e-150	48.68	gene:FBgn0262733 transcript:FBtr0100508	[more]
Src64B	7.354e-150	48.68	gene:FBgn0262733 transcript:FBtr0100505	[more]
Src64B	7.354e-150	48.68	gene:FBgn0262733 transcript:FBtr0100504	[more]
Src64B	7.354e-150	48.68	gene:FBgn0262733 transcript:FBtr0304990	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fyna	1.144e-179	53.98	FYN proto-oncogene, Src family tyrosine kinase a [...	[more]
fynb	1.384e-176	53.10	FYN proto-oncogene, Src family tyrosine kinase b [...	[more]
fynb	1.384e-176	53.10	FYN proto-oncogene, Src family tyrosine kinase b [...	[more]
yrk	6.383e-174	53.10	Yes-related kinase [Source:ZFIN;Acc:ZDB-GENE-03013...	[more]
yrk	6.383e-174	53.10	Yes-related kinase [Source:ZFIN;Acc:ZDB-GENE-03013...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccdc13	1.198e-178	53.63	coiled-coil domain containing 13 [Source:Xenbase;A...	[more]
ccdc13	1.752e-178	53.48	coiled-coil domain containing 13 [Source:Xenbase;A...	[more]
ccdc13	3.870e-178	52.54	coiled-coil domain containing 13 [Source:Xenbase;A...	[more]
FGR	4.546e-173	51.81	FGR proto-oncogene, Src family tyrosine kinase [So...	[more]
cthrc1	3.597e-172	52.15	collagen triple helix repeat containing 1 [Source:...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Fyn	7.885e-179	52.75	Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:9560...	[more]
Src	2.132e-172	52.99	Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9...	[more]
Src	2.132e-172	52.99	Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9...	[more]
Src	2.132e-172	52.99	Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9...	[more]
Src	8.015e-170	52.30	Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9...	[more]

BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P27446\|FYN_XIPHE	1.403e-180	53.18	Tyrosine-protein kinase Fyn OS=Xiphophorus helleri...	[more]
sp\|Q6EWH2\|FYNA_DANRE	8.639e-179	53.98	Tyrosine-protein kinase fyna OS=Danio rerio OX=795...	[more]
sp\|P39688\|FYN_MOUSE	5.515e-178	52.75	Tyrosine-protein kinase Fyn OS=Mus musculus OX=100...	[more]
sp\|P13406\|FYN_XENLA	1.545e-177	52.54	Tyrosine-protein kinase Fyn OS=Xenopus laevis OX=8...	[more]
sp\|P06241\|FYN_HUMAN	1.759e-177	52.54	Tyrosine-protein kinase Fyn OS=Homo sapiens OX=960...	[more]

BLAST of Tyrosine-protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0V0J867	0.000e+0	59.17	Tyrosine-protein kinase OS=Schistocephalus solidus...	[more]
A0A3Q0KT01	0.000e+0	60.71	Tyrosine-protein kinase OS=Schistosoma mansoni OX=...	[more]
A0A4Z2CUE7	0.000e+0	61.06	Tyrosine-protein kinase OS=Schistosoma japonicum O...	[more]
A0A4E0S0K6	0.000e+0	59.07	Tyrosine-protein kinase OS=Fasciola hepatica OX=61...	[more]
A0A0V0J6V3	0.000e+0	55.53	Tyrosine-protein kinase OS=Schistocephalus solidus...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fyna	7.129e-179	53.98	tyrosine-protein kinase fyna [Source:NCBI gene;Acc...	[more]
yrk	9.407e-174	53.10	proto-oncogene tyrosine-protein kinase Yrk [Source...	[more]
SRC	1.743e-170	51.84	proto-oncogene tyrosine-protein kinase Src-like [S...	[more]
clul1	1.192e-167	51.33	tyrosine-protein kinase yes [Source:NCBI gene;Acc:...	[more]
SRC	7.182e-167	51.97	proto-oncogene tyrosine-protein kinase Src-like [S...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
clul1	2.042e-169	51.09	clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GE...	[more]
hck	8.495e-157	47.66	HCK proto-oncogene, Src family tyrosine kinase [So...	[more]
frk	1.128e-155	49.56	fyn-related Src family tyrosine kinase [Source:ZFI...	[more]
hck	1.411e-152	46.77	HCK proto-oncogene, Src family tyrosine kinase [So...	[more]
ENSPMAT00000006670.1	1.742e-139	52.49	pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
CDC15	7.564e-20	26.32	Protein kinase of the Mitotic Exit Network; locali...	[more]
PHO85	8.963e-20	30.67	Cyclin-dependent kinase; has ten cyclin partners; ...	[more]
HOG1	2.469e-19	36.45	Mitogen-activated protein kinase involved in osmor...	[more]
BCK1	9.891e-19	29.92	MAPKKK acting in the protein kinase C signaling pa...	[more]
GIN4	8.977e-18	31.34	Protein kinase involved in bud growth and assembly...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47195	5.785e-84	46.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49804	2.436e-74	49.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40994	1.686e-68	44.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49315	8.429e-65	41.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33736	3.529e-64	40.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fyna	0.000e+0	54.87	tyrosine-protein kinase fyna [Source:NCBI gene;Acc...	[more]
yrk	1.382e-175	53.32	proto-oncogene tyrosine-protein kinase Yrk [Source...	[more]
SRC	1.039e-173	52.99	SRC proto-oncogene, non-receptor tyrosine kinase [...	[more]
src	9.011e-169	52.33	proto-oncogene tyrosine-protein kinase Src [Source...	[more]
YES1	1.041e-168	51.55	YES proto-oncogene 1, Src family tyrosine kinase [...	[more]

BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000020289.1	0.000e+0	100.00	SMESG000020289.1	[more]
SMESG000020289.1	0.000e+0	96.55	SMESG000020289.1	[more]
SMESG000020289.1	0.000e+0	100.00	SMESG000020289.1	[more]
SMESG000003807.1	0.000e+0	56.99	SMESG000003807.1	[more]
SMESG000016930.1	0.000e+0	49.22	SMESG000016930.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30031519 ID=SMED30031519|Name=Tyrosine-protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2207bp
AAATTAGAATTTTTGAATTAAAAATGTATTCGACAGATTTATTTTTGTGA
CAAAATGGGTAATTGTGTTGATAAATTAGAAAATGGCTCCTTAAGAGATA
ACAAATATTTACCAAATCAGAAAGAAAATATCGATAAAGATGATTATAAG
TTTTCAAATGAAAATTCTAATCAAACTCAATCATATCCGTCTACTCCACA
TATGACTAAAGCTAATGTAAGTTCCAGTAGCTCTGTTCCTATTGAAAAAA
AATATTCAATAAGTAGTTTTGCAAATTCCAATGTCTCTAAACTAACGAAT
TCTCAAGAGGGTTCTCACATGTCAGTTAAAATTTCAGAGTCTTGTACTAC
TTTTATAAATAATTCTGGTGAAAATATCTTACCTCGTTTGTCTGATTGTT
CAGATCGTAATTGGAATGTTAGATCAGATTCTCCAAGTAGGCACAGTCAG
TCATCATCTCTATTTACAACTTCAACAAATTATGGATCGAAAACAGATAT
TCATCGAAATAGATTTTTGATAGCTATCTTCGACTATAAAGCAAGAACAA
TTGATGAAATATATCTTAAAAAAGGCGATAGAGTTATTTTACTAGAATCT
AATGATCCAGATTGGTGGCTAGTCGAACAACGAGCAACGGGAAATAGAGG
CTACGTGCCTTCATCATTTTTGGCTGTGGAATATTCATTTGAATCTCAGG
ATTGGTATTTCCCGTTCATTACAAGAAAAGACGCCGAAAGATCATTGCTA
CAACCAGGAAATGCCCGAGGCTGTTTTTTAATTCGAGCTAGTGAAACTAC
TCAAGGAGCCCAATGTTTGTCGGTATTGGATCATCCGGTTAACAGTGGCT
ATGTTGTTAATCATTACAAAATCAAAAAAACCAATCAAGGCGCTGTGTAT
ATTACCACCAAAAAAATCTTTCCTAGTCTTACTCAGTTAATTTTATATTA
CTCAAATGCACCAAATGGCTTATGCTGTTCACTGTCACATCCATGTTCAA
AGCCAACTCCGATAATAAGTGATTTGTCATATAAAACCAAAGATAAATGG
GAAATCGACAGGTCCTCCTTACAGCTCAGTGAAAAATTAGGTGCTGGTCA
ATTCGGAGAAGTTTGGAGAGGACTTTGGAATGGAACAACACCAGTAGCAG
TTAAGACTTTAAAGCCAGGTACGATGACAAAGGAAGATTTTTTAAAAGAG
GCGAAAGTAATGAAGAGTTTATGTCACATTAATCTAGTTCGATTATACGC
GATATGCTCGGATGAACCAATTTATATCGTAACCGAACTCATGTCGAAAG
GCAGTTTATTACAGTACCTCAGATCAGAAACAGGCCAAGCAATGATTTTA
AAACAACTTATCGATTTTATTTCACAGATTGCAAATGGAATGGCGTATTT
GGAAAACAGTGGCTATGTTCATCGAGATTTAGCAGCTCGTAATATTCTTG
TTGGTGAAGGAGAAATTTGTAAAATCGCCGATTTCGGTCTGGCGCGTTTA
ATTGATGCAGGGTGTGAAATGTATGAAGCTAGCCAAGGATCTCGATTTCC
AGTAAAATGGACAGCACCAGAAGCCGCTTTATGGGGTAAATTCAGCACCA
AGTCCGATGTTTGGTCATTTGGCGTGTTAATTTATGAAATTATAACCCGT
GGTCAAGTACCATTTCCTTCAATGAGCAACTCCGAAGCACTTCAAAATAT
CGAGACAGGATATAGGATGCCAAGTCCGAAACAATGTCCCAGTTATATAT
ATGAAATTATGCTTCAATGTTGGAATTTACGTCCTGAACATAGACCAACC
TTTGCCAGTTTACGAGACGTATTCGATGATCTTTTTATTACTGCTGAATC
AGGATATCGAGCCGCAGAGTGTATCTCTCGTTAGCTTTATTATCAAAAAT
TGATCTGAATTTGCCTGGCTCTGATTCCACTGCTGTCTTCCACCCAGTGT
GATCTCTACACCTTCATTGTGGACAACAGTGCCTGAGACGTTCTAGTCAT
GTTGCCTTATCTGGTCCGAGGGGTGGACGATTATCTCGATCTCAGATTAA
ATTTCGGCTACCTCTAGATTCAACCATTGTCTAGAATAAAGGACTTATCT
CAGCTTTTCAAAATTACTATTAATATTACCATAATAGATTTTTAATTGAT
TTTTTTAATATTGCTTTCATTGTTTTTTATCTACCATATTGATCTGAGAG
ATTGACA

protein sequence of SMED30031519-orf-1

>SMED30031519-orf-1 ID=SMED30031519-orf-1|Name=SMED30031519-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=610bp
MGNCVDKLENGSLRDNKYLPNQKENIDKDDYKFSNENSNQTQSYPSTPHM
TKANVSSSSSVPIEKKYSISSFANSNVSKLTNSQEGSHMSVKISESCTTF
INNSGENILPRLSDCSDRNWNVRSDSPSRHSQSSSLFTTSTNYGSKTDIH
RNRFLIAIFDYKARTIDEIYLKKGDRVILLESNDPDWWLVEQRATGNRGY
VPSSFLAVEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQ
GAQCLSVLDHPVNSGYVVNHYKIKKTNQGAVYITTKKIFPSLTQLILYYS
NAPNGLCCSLSHPCSKPTPIISDLSYKTKDKWEIDRSSLQLSEKLGAGQF
GEVWRGLWNGTTPVAVKTLKPGTMTKEDFLKEAKVMKSLCHINLVRLYAI
CSDEPIYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLE
NSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPV
KWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIE
TGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASLRDVFDDLFITAESG
YRAAECISR*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000017	photoreceptor neuron
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036860	SH2_dom_sf
IPR036028	SH3-like_dom_sf
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR001452	SH3_domain
IPR000980	SH2
IPR020635	Tyr_kinase_cat_dom
IPR017441	Protein_kinase_ATP_BS
IPR008266	Tyr_kinase_AS
IPR000719	Prot_kinase_dom
IPR011009	Kinase-like_dom_sf

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0016310	phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation

Vocabulary: **molecular function**
Term	Definition
GO:0004672	protein kinase activity
GO:0005515	protein binding
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0000166	nucleotide binding
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PRINTS	PR00109	TYRKINASE	coord: 448..466 score: 67.23 coord: 561..583 score: 47.63 coord: 410..423 score: 53.12 coord: 517..539 score: 55.21 coord: 498..508 score: 67.07
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 339..588 e-value: 1.3E-92 score: 309.7
IPR000980	SH2 domain	PRINTS	PR00401	SH2DOMAIN	coord: 267..277 score: 41.64 coord: 217..231 score: 48.68 coord: 238..248 score: 58.75 coord: 250..261 score: 37.29 coord: 288..302 score: 37.12
IPR000980	SH2 domain	SMART	SM00252	SH2_5	coord: 215..305 e-value: 4.4E-27 score: 106.0
IPR000980	SH2 domain	PFAM	PF00017	SH2	coord: 217..299 e-value: 2.5E-20 score: 72.4
IPR000980	SH2 domain	PROSITE	PS50001	SH2	coord: 217..314 score: 21.408
IPR001452	SH3 domain	PRINTS	PR00452	SH3DOMAIN	coord: 167..182 score: 30.84 coord: 184..193 score: 29.96 coord: 197..209 score: 28.34 coord: 153..163 score: 31.94
IPR001452	SH3 domain	SMART	SM00326	SH3_2	coord: 153..210 e-value: 1.7E-15 score: 67.5
IPR001452	SH3 domain	PFAM	PF00018	SH3_1	coord: 156..203 e-value: 5.2E-13 score: 48.4
IPR001452	SH3 domain	PROSITE	PS50002	SH3	coord: 150..211 score: 24.087
IPR020635	Tyrosine-protein kinase, catalytic domain	SMART	SM00219	tyrkin_6	coord: 339..590 e-value: 3.2E-135 score: 465.2
None	No IPR available	GENE3D	G3DSA:3.30.200.20		coord: 329..414 e-value: 6.2E-35 score: 121.2
None	No IPR available	GENE3D	G3DSA:2.30.30.40		coord: 154..206 e-value: 1.5E-16 score: 61.7
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 415..603 e-value: 7.1E-56 score: 191.0
None	No IPR available	PIRSF	PIRSF000615	TyrPK_CSF1-R	coord: 21..133 e-value: 380.0 score: -3.5 coord: 424..604 e-value: 1.5E-53 score: 179.9 coord: 322..432 e-value: 3.1E-15 score: 53.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 36..60
None	No IPR available	PANTHER	PTHR24418:SF224	TYROSINE-PROTEIN KINASE FGR	coord: 138..604
None	No IPR available	PANTHER	PTHR24418	TYROSINE-PROTEIN KINASE	coord: 138..604
None	No IPR available	CDD	cd11845	SH3_Src_like	coord: 154..205 e-value: 4.27177E-17 score: 73.3856
None	No IPR available	CDD	cd05034	PTKc_Src_like	coord: 343..591 e-value: 1.05862E-165 score: 470.612
IPR036860	SH2 domain superfamily	GENE3D	G3DSA:3.30.505.10		coord: 207..316 e-value: 5.2E-30 score: 105.5
IPR036860	SH2 domain superfamily	SUPERFAMILY	SSF55550	SH2 domain	coord: 212..359
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 345..367
IPR008266	Tyrosine-protein kinase, active site	PROSITE	PS00109	PROTEIN_KINASE_TYR	coord: 454..466
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 339..595 score: 41.234
IPR036028	SH3-like domain superfamily	SUPERFAMILY	SSF50044	SH3-domain	coord: 154..236
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 325..591