origin recognition complex subunit 3

Overview
Nameorigin recognition complex subunit 3
Smed IDSMED30031477
Length (bp)1871
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of origin recognition complex subunit 3 (SMED30031477) t-SNE clustered cells

Violin plots show distribution of expression levels for origin recognition complex subunit 3 (SMED30031477) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of origin recognition complex subunit 3 (SMED30031477) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for origin recognition complex subunit 3 (SMED30031477) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031477

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30031477h1SMcG0006624 SmedASXL_013039SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30031477h1SMcG0006624 SmedASXL_013039SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30031477h1SMcG0006624 dd_Smed_v6_15606_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
zeta neoblastSMED30031477h1SMcG0006624 dd_Smed_v4_15606_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30031477h1SMcG0006624 SmWIOct06_032773GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30031477h1SMcG0006624 SMED_10775_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30031477h1SMcG0006624 SMED_10775_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30031477h1SMcG0006624 SMED_31753_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30031477h1SMcG0006624 SMED_31753_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Human
Match: ORC3 (origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489])

HSP 1 Score: 152.14 bits (383), Expect = 3.655e-38
Identity = 159/675 (23.56%), Postives = 302/675 (44.74%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP-----KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPS-TDLT---ELNLPISSKS---SLIALDEW-----------LNSKEFFILKQ-----IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKEN-----CQILSDFMGNALKLASKVTTRESLSESIPVTIPNS------RRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y++I  +     E    + N+  F  +I+FLQ ++   FQ K   DL      + +P   ++LG N  D D T+ +L + +      YVV L+++DC  +K  L+ +I  ++    D+    E ++ ++ +    S+ +L  W           + SK+     Q     +++I++D+E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S  + L   L  LL +  FP +++ ++   + N +F+  D+S+ + I+  Q  L +H  S                                SF +  E Q+ +      TN   +         N+  YH     + R L    S  P+  LG +  +++   L+  + +S E  S L+L++ L+ +E++ +++       +  EN      + + +F+     L ++    E  S S P  +  +      +  L+ +  R + KQT F    ++  N++   ++++L  P    L  +E ++       R ++N + +  L   L+ P+ Y+ +++L+ +    I N  PD CI YK  ++  RLI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   43 RFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSG-FQ-KNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTN-IFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQSLDAETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPL--HEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEE-GCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 711
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Human
Match: ORC3 (origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489])

HSP 1 Score: 147.132 bits (370), Expect = 1.737e-36
Identity = 159/675 (23.56%), Postives = 301/675 (44.59%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP-----KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPS-TDLT---ELNLPISSKS---SLIALDEW-----------LNSKEFFILKQ-----IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKEN-----CQILSDFMGNALKLASKVTTRESLSESIPVTIPNS------RRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y++I  +     E    + N+  F  +I+FLQ ++   FQ K   DL      + +P   ++LG N  D D T+ +L + +      YVV L+++DC  +K  L+ +I  ++    D+    E ++ ++ +    S+ +L  W           + SK+     Q     +++I++D+E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S  + L   L  LL +  FP +++ ++   + N +F+  D+S+ + I+  Q  L +H  S                                SF +  E Q+ +      TN   +         N+  YH     + R L    S  P+  LG +  +++   L+  + +S E  S L+L++ L+ +E++ +++       +  EN      + + +F+     L  +    E  S S P  +  +      +  L+ +  R + KQT F    ++  N++   ++++L  P    L  +E ++       R ++N + +  L   L+ P+ Y+ +++L+ +    I N  PD CI YK  ++  RLI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   43 RFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSG-FQ-KNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTN-IFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQSL-DETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPL--HEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEE-GCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 710
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Human
Match: ORC3 (origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489])

HSP 1 Score: 121.324 bits (303), Expect = 2.304e-28
Identity = 119/501 (23.75%), Postives = 226/501 (45.11%), Query Frame = 3 
Query:  501 IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKEN-----CQILSDFMGNALKLASKVTTRESLSESIPVTIPNS------RRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            +++I++D+E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S  + L   L  LL +  FP +++ ++   + N +F+  D+S+ + I+  Q  L +H  S                                SF +  E Q+ +      TN   +         N+  YH     + R L    S  P+  LG +  +++   L+  + +S E  S L+L++ L+ +E++ +++       +  EN      + + +F+     L  +    E  S S P  +  +      +  L+ +  R + KQT F    ++  N++   ++++L  P    L  +E ++       R ++N + +  L   L+ P+ Y+ +++L+ +    I N  PD CI YK  ++  RLI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   72 VVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTN-IFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQSL-DETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPL--HEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEE-GCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 567
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Fly
Match: Orc3 (gene:FBgn0005654 transcript:FBtr0087768)

HSP 1 Score: 156.377 bits (394), Expect = 6.989e-40
Identity = 162/641 (25.27%), Postives = 275/641 (42.90%), Query Frame = 3 
Query:  198 KTEYDLP-KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPI---------------SSKSSLIALDEWL--NSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGML----NNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHL--NSPF-------HSFWKESELQSID------------YLELCSTNAPIINV---RNYHKTS-------------VFIC--RWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFA----NTNLSNE------KENCQILSDFMGNALKLASKVTTRESLSESIPVTIPN-------------SRRNLKEQIFRNA--NKQTHFLQ----DFCNWLHEWL--------KQHLPHYSALIGYEELFM-DDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTW 1811
            + E D P +++P   +L G N PD    +TAL  ++     + V  L+SRDC +LK  +E ++  ++      E                     S+ ++  L  W   N       +Q+++I+ D E FN  +LQ LI I S+     PFVL++G+++A+ ++ G L    +++  +RV   F   A+P+ L  +    LLS  +   LS + + ++ + +F+  D+SI   IQ +++CL +H    + F        +  +  +L   D            Y+E  +    II V    +Y K               +F C   +L +L    P   LG    +++   L   + ++ E +  L+++  LS +E V  V+ A       L  E       E C  +      A++LA     + +++ +I  T PN             SR+ LK+Q+ + +  +K  H L      F   L + L        + HL          ELF+  D+ T R N+  + +  L   L+ P  Y+  K   L     +   LPD  ++YK  ++  R+I L+DWLQAF  +V   D +    +      Q RF +AV EL+FLG++K  K K D    LTW
Sbjct:   86 QAERDTPDEVLPTAALLTGINQPDHLSQFTALTQRLHAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVEQMEDEDEDEDGAERDRKRLRRSQCTMKQLKSWYTNNFDSEQKRRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVLGVATAMTAVHGTLPYHVSSKIRLRV---FQTQAAPTGLNEVLDKVLLSPKYAFHLSGKTFKFLTH-IFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSKALGRIKQLTHEDMETIRRLPSFRPYVEQINDCKRIIAVLTDDDYLKKKLPQLLRDCLLHFLLFRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIISTPEYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAVLRPKLEAIRLAVDEVVKATMA-TITTTSPNETRQATDHLTPVASRQELKDQLLQRSKEDKMRHQLNTPTTQFGRALQKTLQLIETQIVQDHLRALQDAPPIHELFVFSDIATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTLPDLSVVYKLHLECGRMINLFDWLQAFRSVVSDSDHEEVAQEQIDPQIQARFTRAVAELQFLGYIKMSKRKTDHATRLTW 721
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Fly
Match: Orc3 (gene:FBgn0005654 transcript:FBtr0087769)

HSP 1 Score: 156.377 bits (394), Expect = 6.989e-40
Identity = 162/641 (25.27%), Postives = 275/641 (42.90%), Query Frame = 3 
Query:  198 KTEYDLP-KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPI---------------SSKSSLIALDEWL--NSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGML----NNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHL--NSPF-------HSFWKESELQSID------------YLELCSTNAPIINV---RNYHKTS-------------VFIC--RWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFA----NTNLSNE------KENCQILSDFMGNALKLASKVTTRESLSESIPVTIPN-------------SRRNLKEQIFRNA--NKQTHFLQ----DFCNWLHEWL--------KQHLPHYSALIGYEELFM-DDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTW 1811
            + E D P +++P   +L G N PD    +TAL  ++     + V  L+SRDC +LK  +E ++  ++      E                     S+ ++  L  W   N       +Q+++I+ D E FN  +LQ LI I S+     PFVL++G+++A+ ++ G L    +++  +RV   F   A+P+ L  +    LLS  +   LS + + ++ + +F+  D+SI   IQ +++CL +H    + F        +  +  +L   D            Y+E  +    II V    +Y K               +F C   +L +L    P   LG    +++   L   + ++ E +  L+++  LS +E V  V+ A       L  E       E C  +      A++LA     + +++ +I  T PN             SR+ LK+Q+ + +  +K  H L      F   L + L        + HL          ELF+  D+ T R N+  + +  L   L+ P  Y+  K   L     +   LPD  ++YK  ++  R+I L+DWLQAF  +V   D +    +      Q RF +AV EL+FLG++K  K K D    LTW
Sbjct:   86 QAERDTPDEVLPTAALLTGINQPDHLSQFTALTQRLHAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVEQMEDEDEDEDGAERDRKRLRRSQCTMKQLKSWYTNNFDSEQKRRQLVVILPDFECFNASVLQDLILILSAHCGSLPFVLVLGVATAMTAVHGTLPYHVSSKIRLRV---FQTQAAPTGLNEVLDKVLLSPKYAFHLSGKTFKFLTH-IFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSKALGRIKQLTHEDMETIRRLPSFRPYVEQINDCKRIIAVLTDDDYLKKKLPQLLRDCLLHFLLFRCSLEFLTELVGDLPRCPLGKLRRELYVNCLNRAIISTPEYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLELGEACTAVLRPKLEAIRLAVDEVVKATMA-TITTTSPNETRQATDHLTPVASRQELKDQLLQRSKEDKMRHQLNTPTTQFGRALQKTLQLIETQIVQDHLRALQDAPPIHELFVFSDIATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTLPDLSVVYKLHLECGRMINLFDWLQAFRSVVSDSDHEEVAQEQIDPQIQARFTRAVAELQFLGYIKMSKRKTDHATRLTW 721
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Zebrafish
Match: orc3 (origin recognition complex, subunit 3 [Source:ZFIN;Acc:ZDB-GENE-030131-6247])

HSP 1 Score: 163.31 bits (412), Expect = 3.338e-42
Identity = 152/625 (24.32%), Postives = 283/625 (45.28%), Query Frame = 3 
Query:  186 WFQVKTEYDLPKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLK----KVLECIIKSIIPSTDLTELN--LPISSKSSLIALDEWLNS--------KEFFILKQ---IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSD-LLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSID-----------YLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKEN-----CQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRN----LKEQIFRNANKQTHFLQDF-------CNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPA----KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            W Q  +E      +P   ++LG N PD   T+ +LC+ + +    +VV + +++C ++K    KVLE ++   +   +  E +  LP  ++ ++ AL +W  +        K    L+Q   +++I +D E FN ++LQ  I I S    + PF+ + G++++  ++   L +     +    F S S +  L ++F   +L+  FP +LSSR+   +V  +F+  D+S+ + ++  QF + +H NS                                SF +  E Q  +             E+C T   + ++  YHK    I + L  L S  P+  LG    ++     +  L  + E  S ++L++ L+  E+V  +   +  L +          Q + DF+     L S  +   S++ +I   I   R+     L++ +    +++T  +  F         ++   ++++L         E  +       R  +N + + +++  LS+P+ Y+ ++SL+ ++  +IS+  PD CI+YK  ++  RLI LYDWL+AF  ++   E +D DS        +   RF +AV E+EFLGFVK  K K D +  LTWG 
Sbjct:   91 WRQRTSE------IPTAALMLGVNVPDHAMTFRSLCNLLQDSVTPFVVSVHAKECAAVKHLIQKVLEQLMGKAVSVDEEQEEDAALPQKAQCTISALCQWYKTATKKCSQKKNDNGLRQSLPVVVIFKDFEAFNSQVLQDFIHICSRYIQELPFIFVFGIATSPSAIQHRLPHSVSSLLCIEVFQSVSCTQHLASVFDKLILNAHFPFKLSSRVIQVLVG-IFLYHDFSVQNFVKGLQFSMLEHFNSQPLSVLCCRKREALLCAKTLSQQNVERIRHLPSFMRYVETQEPEEQVKLLTSDQHVKEVCQT--LLKSLHKYHKNYFPILQCLHSLTSSLPKFPLGKHIRELHVSCNEKNLWETEEYDSAMQLLRILAKNELVAALQGCSDILQSASTKRMQTVFQQVEDFINRLETLESVSSEDSSVNGAISGKIDYQRKTDLFQLQKTLLEKESRRTKKMSPFEVLRSQVIEFIDSLVREYLTPAHLQPLSEVCYFSSSGILRQRLNVTPRTSIQAALSHPYYYLQNESLKTNA-GTISSAAPDLCIVYKLHLECGRLINLYDWLEAFVTVLSAAEDQDADSGDHGQLDSLKHARFIQAVSEMEFLGFVKSTKQKTDHVARLTWGG 705
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Xenopus
Match: orc3 (origin recognition complex subunit 3 [Source:NCBI gene;Acc:100125181])

HSP 1 Score: 148.288 bits (373), Expect = 4.606e-37
Identity = 165/635 (25.98%), Postives = 292/635 (45.98%), Query Frame = 3 
Query:  132 NELSFGKIIQFLQINYENWFQVKTEYDL---PKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELN-----LPISSK---SSLIALDEW------LNSKE------FFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLS--NEKENCQILSDFMGNAL-KLASKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPA--KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            N+  F  +I FL+ ++ ++   K ++        +P   ++LG N  D D T+ +L D + E    YVV L+S++C  +K++L+ ++  ++ +T   EL+     + IS +    SL +L  W      +N K+       +    +++I +D+E F   +LQ  I I+S    + P VL+ G++++   +  +L++    R+    F S S ++ L   +  LL +  FP +LS R    ++  +F+  D+S+ + I+  Q  + +H  +                                SF    E Q+ +      TN   +          + +YH+    I R L       P+  LG +  +++   L+  +  + +  S L L++ L+ +EIV  +      L+  +EKE        +G+ L KL   +   +SL E I + +      L+ +  R A K T F    QD  +++   ++++L     L  +E ++     T R ++N + +  L   L+ P +Y+  K+L  +   S+SN  PD CI YK  ++  RLI LYDWL+AF+ +V   E  D DS     ++T  RF +AV ELE LGFVK  K K D +  LTWG 
Sbjct:   68 NKRLFENLIGFLRKSHADFHDKKDDWSCRMRASEIPTAALVLGVNVTDHDLTFNSLADILHETITPYVVLLQSKECPGIKQLLQKLLIQLMGNTADIELDEEEEQVTISQRKMNCSLASLSGWYKRATKVNEKKRSSTSTHWESPPVVVIFKDLESFTASVLQEFIVISSGYVQELPLVLVFGIATSPMIIHRLLSHSVSSRLCIELFQSMSCTEHLATVVDQLLLTNHFPFKLSGRALQVLIT-IFLYHDFSVQNFIKGLQLSVVEHFYTQPLSVLCCSLPESRKRIKNLSHAQCENIRHLSSFMSYVESQTPENQVKLLTNDSFLKEMTQEFLERLTSYHENFTPILRCLHHFTCILPKYPLGKQVRELYCACLEKKVWETEDYNSALLLLRMLAKDEIVTTLQKCVAVLTPYSEKE--------LGHTLEKLEEFLIHFQSL-EGIFLKL------LEMKETRRAKKLTKFEMLRQDVVDFIDCIVREYLVPPEMLPLHEVVYFSAASTLRRHLNAAPRVALHTALNNPASYL--KTLE-NEAGSVSNVAPDICIAYKLHLECGRLINLYDWLEAFSTVVHAGEGSDSDSAQQVDEVTHARFIRAVSELELLGFVKPTKQKTDHVARLTWGG 683
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Xenopus
Match: orc3 (origin recognition complex subunit 3 [Source:NCBI gene;Acc:100125181])

HSP 1 Score: 144.821 bits (364), Expect = 6.853e-36
Identity = 160/647 (24.73%), Postives = 287/647 (44.36%), Query Frame = 3 
Query:  132 NELSFGKIIQFLQINYENWFQVKTEYDL---PKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPST-----DLTELNLPISSKS---SLIALDEWL---------------NSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLS--NEKE---NCQILSDFMGNALKLASKVTTRESLSESIPVTIPN-------SRRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPA--KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            N+  F  +I FL+ ++ ++   K ++        +P   ++LG N  D D T+ +L D + E    YVV L+S++C  +K++L+ ++  ++ +T     D  E  + IS +    SL +L  W                ++   +    +++I +D+E F   +LQ  I I+S    + P VL+ G++++   +  +L++    R+    F S S ++ L   +  LL +  FP +LS R    ++  +F+  D+S+ + I+  Q  + +H  +                                SF    E Q+ +      TN   +          + +YH+    I R L       P+  LG +  +++   L+  +  + +  S L L++ L+ +EIV  +      L+  +EKE     + L +F+ +   L       E    S    +          ++ L+ +  R A K T F    QD  +++   ++++L     L  +E ++     T R ++N + +  L   L+ P +Y+  K+L  +   S+SN  PD CI YK  ++  RLI LYDWL+AF+ +V   E  D DS     ++T  RF +AV ELE LGFVK  K K D +  LTWG 
Sbjct:   41 NKRLFENLIGFLRKSHADFHDKKDDWSCRMRASEIPTAALVLGVNVTDHDLTFNSLADILHETITPYVVLLQSKECPGIKQLLQKLLIQLMGNTADIELDEEEEQVTISQRKMNCSLASLSGWYKRATKKPASPKKKRSSTSTHWESPPVVVIFKDLESFTASVLQEFIVISSGYVQELPLVLVFGIATSPMIIHRLLSHSVSSRLCIELFQSMSCTEHLATVVDQLLLTNHFPFKLSGRALQVLIT-IFLYHDFSVQNFIKGLQLSVVEHFYTQPLSVLCCSLPESRKRIKNLSHAQCENIRHLSSFMSYVESQTPENQVKLLTNDSFLKEMTQEFLERLTSYHENFTPILRCLHHFTCILPKYPLGKQVRELYCACLEKKVWETEDYNSALLLLRMLAKDEIVTTLQKCVAVLTPYSEKELGHTLEKLEEFLIHFQSLEENTLNGEDEDTSPQKALQKKTDLYQLQKKLLEMKETRRAKKLTKFEMLRQDVVDFIDCIVREYLVPPEMLPLHEVVYFSAASTLRRHLNAAPRVALHTALNNPASYL--KTLE-NEAGSVSNVAPDICIAYKLHLECGRLINLYDWLEAFSTVVHAGEGSDSDSAQQVDEVTHARFIRAVSELELLGFVKPTKQKTDHVARLTWGG 683
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Xenopus
Match: orc3 (origin recognition complex subunit 3 [Source:NCBI gene;Acc:100125181])

HSP 1 Score: 145.206 bits (365), Expect = 7.078e-36
Identity = 160/647 (24.73%), Postives = 287/647 (44.36%), Query Frame = 3 
Query:  132 NELSFGKIIQFLQINYENWFQVKTEYDL---PKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPST-----DLTELNLPISSKS---SLIALDEWL---------------NSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLS--NEKE---NCQILSDFMGNALKLASKVTTRESLSESIPVTIPN-------SRRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPA--KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            N+  F  +I FL+ ++ ++   K ++        +P   ++LG N  D D T+ +L D + E    YVV L+S++C  +K++L+ ++  ++ +T     D  E  + IS +    SL +L  W                ++   +    +++I +D+E F   +LQ  I I+S    + P VL+ G++++   +  +L++    R+    F S S ++ L   +  LL +  FP +LS R    ++  +F+  D+S+ + I+  Q  + +H  +                                SF    E Q+ +      TN   +          + +YH+    I R L       P+  LG +  +++   L+  +  + +  S L L++ L+ +EIV  +      L+  +EKE     + L +F+ +   L       E    S    +          ++ L+ +  R A K T F    QD  +++   ++++L     L  +E ++     T R ++N + +  L   L+ P +Y+  K+L  +   S+SN  PD CI YK  ++  RLI LYDWL+AF+ +V   E  D DS     ++T  RF +AV ELE LGFVK  K K D +  LTWG 
Sbjct:   66 NKRLFENLIGFLRKSHADFHDKKDDWSCRMRASEIPTAALVLGVNVTDHDLTFNSLADILHETITPYVVLLQSKECPGIKQLLQKLLIQLMGNTADIELDEEEEQVTISQRKMNCSLASLSGWYKRATKKPASPKKKRSSTSTHWESPPVVVIFKDLESFTASVLQEFIVISSGYVQELPLVLVFGIATSPMIIHRLLSHSVSSRLCIELFQSMSCTEHLATVVDQLLLTNHFPFKLSGRALQVLIT-IFLYHDFSVQNFIKGLQLSVVEHFYTQPLSVLCCSLPESRKRIKNLSHAQCENIRHLSSFMSYVESQTPENQVKLLTNDSFLKEMTQEFLERLTSYHENFTPILRCLHHFTCILPKYPLGKQVRELYCACLEKKVWETEDYNSALLLLRMLAKDEIVTTLQKCVAVLTPYSEKELGHTLEKLEEFLIHFQSLEENTLNGEDEDTSPQKALQKKTDLYQLQKKLLEMKETRRAKKLTKFEMLRQDVVDFIDCIVREYLVPPEMLPLHEVVYFSAASTLRRHLNAAPRVALHTALNNPASYL--KTLE-NEAGSVSNVAPDICIAYKLHLECGRLINLYDWLEAFSTVVHAGEGSDSDSAQQVDEVTHARFIRAVSELELLGFVKPTKQKTDHVARLTWGG 708
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Xenopus
Match: orc3 (origin recognition complex subunit 3 [Source:NCBI gene;Acc:100125181])

HSP 1 Score: 141.739 bits (356), Expect = 8.508e-35
Identity = 158/649 (24.35%), Postives = 282/649 (43.45%), Query Frame = 3 
Query:  132 NELSFGKIIQFLQINYENWFQVKTEYDL---PKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSL-------KKVLECIIKSIIPSTDLTELNLPISSKS---SLIALDEWL---------------NSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLS--NEKE---NCQILSDFMGNALKLASKVTTRESLSESIPVTIPN-------SRRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPA--KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            N+  F  +I FL+ ++ ++   K ++        +P   ++LG N  D D T+ +L D + E    YVV L+S++C  +       K +++ +  +     D  E  + IS +    SL +L  W                ++   +    +++I +D+E F   +LQ  I I+S    + P VL+ G++++   +  +L++    R+    F S S ++ L   +  LL +  FP +LS R    ++  +F+  D+S+ + I+  Q  + +H  +                                SF    E Q+ +      TN   +          + +YH+    I R L       P+  LG +  +++   L+  +  + +  S L L++ L+ +EIV  +      L+  +EKE     + L +F+ +   L       E    S    +          ++ L+ +  R A K T F    QD  +++   ++++L     L  +E ++     T R ++N + +  L   L+ P +Y+  K+L  +   S+SN  PD CI YK  ++  RLI LYDWL+AF+ +V   E  D DS     ++T  RF +AV ELE LGFVK  K K D +  LTWG 
Sbjct:   63 NKRLFENLIGFLRKSHADFHDKKDDWSCRMRASEIPTAALVLGVNVTDHDLTFNSLADILHETITPYVVLLQSKECPGMWIKQLLQKLLIQLMGNTADIELDEEEEQVTISQRKMNCSLASLSGWYKRATKKPASPKKKRSSTSTHWESPPVVVIFKDLESFTASVLQEFIVISSGYVQELPLVLVFGIATSPMIIHRLLSHSVSSRLCIELFQSMSCTEHLATVVDQLLLTNHFPFKLSGRALQVLIT-IFLYHDFSVQNFIKGLQLSVVEHFYTQPLSVLCCSLPESRKRIKNLSHAQCENIRHLSSFMSYVESQTPENQVKLLTNDSFLKEMTQEFLERLTSYHENFTPILRCLHHFTCILPKYPLGKQVRELYCACLEKKVWETEDYNSALLLLRMLAKDEIVTTLQKCVAVLTPYSEKELGHTLEKLEEFLIHFQSLEENTLNGEDEDTSPQKALQKKTDLYQLQKKLLEMKETRRAKKLTKFEMLRQDVVDFIDCIVREYLVPPEMLPLHEVVYFSAASTLRRHLNAAPRVALHTALNNPASYL--KTLE-NEAGSVSNVAPDICIAYKLHLECGRLINLYDWLEAFSTVVHAGEGSDSDSAQQVDEVTHARFIRAVSELELLGFVKPTKQKTDHVARLTWGG 707
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Xenopus
Match: orc3 (origin recognition complex subunit 3 [Source:NCBI gene;Acc:100125181])

HSP 1 Score: 123.635 bits (309), Expect = 3.148e-29
Identity = 145/592 (24.49%), Postives = 263/592 (44.43%), Query Frame = 3 
Query:  132 NELSFGKIIQFLQINYENWFQVKTEYDL---PKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELN-----LPISSKS---SLIALDEWLN-----SKEFFILKQIILIVEDIELFNVELLQSLIE-----ITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTH-LLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQSIDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKENCQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPA--KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            N+  F  +I FL+ ++ ++   K ++        +P   ++LG N  D D T+ +L D + E    YVV L+S++C  +K++L+ ++  ++ +T   EL+     + IS +    SL +L  W       ++   +   + + + D+  F  +L +         I  S   + P VL+ G++++   +  +L++    R+    F S S ++ L   +   LL+  FP +LS R    ++  +F+  D+S+ + I+  Q  + +H  +           Q +  L  CS       ++N         R  L  F  + ES+                  N ++L +N   +K ++ E + +L  +      N     + L  F        + +  +  L + +   +  +RR         A K T F    QD  +++   ++++L     L  +E ++     T R ++N + +  L   L+ P +Y+  K+L  +   S+SN  PD CI YK  ++  RLI LYDWL+AF+ +V   E  D DS     ++T  RF +AV ELE LGFVK  K K D +  LTWG 
Sbjct:   15 NKRLFENLIGFLRKSHADFHDKKDDWSCRMRASEIPTAALVLGVNVTDHDLTFNSLADILHETITPYVVLLQSKECPGIKQLLQKLLIQLMGNTADIELDEEEEQVTISQRKMNCSLASLSGWYKRATKVNEAIHVNTWLQINLHDLSHFKFDLKEQTNRTDTHVICCSLEGELPLVLVFGIATSPMIIHRLLSHSVSSRLCIELFQSMSCTEHLATVVDQLLLTNHFPFKLSGRALQVLIT-IFLYHDFSVQNFIKGLQLSVVEHFYT-----------QPLSVL-CCSLPESRKRIKNLSHAQCENIRH-LSSFMSYVESQTPE---------------NQVKLLTNDSFLKEMTQEFLERLTSYHE----NFTPILRCLHHF--------TCILPKYPLGKQVSKKMKETRR---------AKKLTKFEMLRQDVVDFIDCIVREYLVPPEMLPLHEVVYFSAASTLRRHLNAAPRVALHTALNNPASYL--KTLE-NEAGSVSNVAPDICIAYKLHLECGRLINLYDWLEAFSTVVHAGEGSDSDSAQQVDEVTHARFIRAVSELELLGFVKPTKQKTDHVARLTWGG 553
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Mouse
Match: Orc3 (origin recognition complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1354944])

HSP 1 Score: 140.584 bits (353), Expect = 1.820e-34
Identity = 152/670 (22.69%), Postives = 280/670 (41.79%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP---KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLK--------KVLECII----KSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQ----------IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPIINVRN---------YHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNL--SNEKE---NCQILSDFMGNALKLASKVTTRESLSESIPVTIPNS------RRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y ++        E    + NE  F  ++ FLQ ++  + +   ++      + +P   ++LG N  D D    +L + +      YVV L+++DC  +K        ++++C +    K +     L + N  + S  S  +        +  I K+          ++LI++ +E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S    L + L  LL +  FP +LS +    + N +F+  D+SI   I+  +  L +H  S                                SF +  E Q +       TN   +  +          YH     + R L +  S  P+  LG +  +++   L+  + +S E +S L+L++ L+ +E+V ++      L  S EK+     Q + DF+     L +     E    S P  +  +      +  L+ +  R   K T F    ++  N++   ++ +L    +   +E ++     T R ++N + +  L   L+ P+ Y+ ++ L       I N  PD CI YK  ++   LI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   50 RFETYSLLWQRMKSETEQLQEELNENLFDNLVDFLQKSHPEFQKNSRDWGSQMKFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTSQLMDCCVDRHSKEVTSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRSPPVVLILKSMESFTSKVLQDFITISSQHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCVELFQSLSCEQHLTVVLDKLLLTPQFPFKLSKKALQVLTN-IFLYHDFSIQSFIKGIKLSLLEHFYSQPLSVLCCDLSEAKKRVNVFSVSQCENIRRLPSFRRYVENQPLGKQVALLTNETFLKEKTQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYKSALQLLRMLAKDELVSILQRCIEVLDSSTEKQLGNTTQKIKDFLTQFQNLDADSKEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRRTKKPTKFEMLRENVMNFIDNLVRDYLLPPESQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEELE----GCIPNTAPDICIAYKLHLECSLLINLVDWAEAFATVVTAAEKMDANSTVSEEMSEVIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 714
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Mouse
Match: Orc3 (origin recognition complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1354944])

HSP 1 Score: 135.961 bits (341), Expect = 5.337e-33
Identity = 152/670 (22.69%), Postives = 279/670 (41.64%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP---KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLK--------KVLECII----KSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQ----------IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPIINVRN---------YHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNL--SNEKE---NCQILSDFMGNALKLASKVTTRESLSESIPVTIPNS------RRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y ++        E    + NE  F  ++ FLQ ++  + +   ++      + +P   ++LG N  D D    +L + +      YVV L+++DC  +K        ++++C +    K +     L + N  + S  S  +        +  I K+          ++LI++ +E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S    L + L  LL +  FP +LS +    + N +F+  D+SI   I+  +  L +H  S                                SF +  E Q +       TN   +  +          YH     + R L +  S  P+  LG +  +++   L+  + +S E +S L+L++ L+ +E+V ++      L  S EK+     Q + DF+     L       E    S P  +  +      +  L+ +  R   K T F    ++  N++   ++ +L    +   +E ++     T R ++N + +  L   L+ P+ Y+ ++ L       I N  PD CI YK  ++   LI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   50 RFETYSLLWQRMKSETEQLQEELNENLFDNLVDFLQKSHPEFQKNSRDWGSQMKFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTSQLMDCCVDRHSKEVTSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRSPPVVLILKSMESFTSKVLQDFITISSQHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCVELFQSLSCEQHLTVVLDKLLLTPQFPFKLSKKALQVLTN-IFLYHDFSIQSFIKGIKLSLLEHFYSQPLSVLCCDLSEAKKRVNVFSVSQCENIRRLPSFRRYVENQPLGKQVALLTNETFLKEKTQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYKSALQLLRMLAKDELVSILQRCIEVLDSSTEKQLGNTTQKIKDFLTQFQNLDDS-KEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRRTKKPTKFEMLRENVMNFIDNLVRDYLLPPESQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEELE----GCIPNTAPDICIAYKLHLECSLLINLVDWAEAFATVVTAAEKMDANSTVSEEMSEVIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 713
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Mouse
Match: Orc3 (origin recognition complex, subunit 3 [Source:MGI Symbol;Acc:MGI:1354944])

HSP 1 Score: 62.003 bits (149), Expect = 5.241e-10
Identity = 63/263 (23.95%), Postives = 116/263 (44.11%), Query Frame = 3 
Query:  132 NELSFGKIIQFLQINYENWFQVKTEYDLPKIM-----PLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLK--------KVLECII----KSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQ----------IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTH-LLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQ 836
            NE  F  ++ FLQ ++   FQ K   D    M     P   ++LG N  D D    +L + +      YVV L+++DC  +K        ++++C +    K +     L + N  + S  S  +        +  I K+          ++LI++ +E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S    L + L   LL+  FP +LS +    + N +F+  D+SI   I+
Sbjct:   15 NENLFDNLVDFLQKSHPE-FQ-KNSRDWGSQMKFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTSQLMDCCVDRHSKEVTSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRSPPVVLILKSMESFTSKVLQDFITISSQHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCVELFQSLSCEQHLTVVLDKLLLTPQFPFKLSKKALQVLTN-IFLYHDFSIQSFIK 274
[Close]
BLAST of origin recognition complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q32PJ3|ORC3_BOVIN (Origin recognition complex subunit 3 OS=Bos taurus OX=9913 GN=ORC3 PE=2 SV=1)

HSP 1 Score: 152.525 bits (384), Expect = 1.340e-37
Identity = 156/678 (23.01%), Postives = 295/678 (43.51%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP---KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKS-------------SLIALDEWL----------------NSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSI---------DYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVD-----FANTNLSNEKENCQILSDFMGNALKL---ASKVTTRESLSESIPVT----IPNSRRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPA----KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y++I  +     E    + N+  F  +++FLQ ++   ++   ++      + +P   ++LG N  D D T  +L + +      YVV L+++DC  +K  L+ ++      + L +  + + SK              S+ +L  W                  S   +    ++LI++D+E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S  + L   L  LL +  FP +LS ++   + N +F+  D+SI + I+  Q  L +H  S                                SF +  E QS          D      T + + N+  YHK    + R L    S  P+  LG +  +++ + L+  + +S E  S L+L++ L+ +E++ ++      F +++        + + +F+     L     +  T +S S+ +  T    +  S   +KE +   + +QT F    +   +++   ++++L        +E L+     T R ++N + +  L   L+ P+ Y+ +++LR +    I N  PD CI YK  ++  RLI L DW +AFA +V   E+ D +S  +    ++   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   43 RFETYQLIWQQMKSETERLQEELNKNLFDSLVEFLQTSHSGLWKNSKDWSCEIKLREIPTAALVLGVNVTDHDLTLRSLTEVLQNNVTPYVVSLQAKDCPDMKHFLQKLV------SQLMDCKVDVQSKEKESVQVIQKNVHYSMDSLSAWYMSVTQKTDPKMPRKKRTSSSQWQSPPVVLILKDMESFTTKVLQDFIIISSQHLHEFPLILIFGIATSPVVIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKLSEKVLQILTN-IFLYHDFSIQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRIRFLSANQCENIRRLPSFRRYVEKQSSEKQVALLTSDKFLKEETQSLLENLHVYHKNYFLVLRCLHQFTSSLPKYPLGRQIRELYCMCLEKSIWDSEEYASVLQLLRLLAKDELMAMLQNCFKLFQSSSGKELGNTAKRIEEFLAQFQSLDETKEEEDTSQSQSKGLQKTDLYHLQKSLLEMKE-LRSTSKRQTKFEVLREQVVSFVDSLVREYLLPPDTQPLHETLYFSSAHTLRQHLNAAPRIALHTALNNPYYYLKNEALRSEE-GCIPNVAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSVTSGERNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 711
[Close]
BLAST of origin recognition complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q5DJU3|ORC3_SPECI (Origin recognition complex subunit 3 OS=Spermophilus citellus OX=9997 GN=ORC3 PE=2 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 4.664e-36
Identity = 153/685 (22.34%), Postives = 304/685 (44.38%), Query Frame = 3 
Query:   30 KKNRQHHDICTRQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP---KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSI----IPSTDLTELNLPISSKSSLIALD---EW-----------LNSKEFFILKQ-----IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVD--FANTNLSNEKE---NCQILSDFMGNALKLASKVTTRESLSESIPVTIPNS-----RRNLKE--QIFRNANKQTHF---LQDFCNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            K   +  D   R   Y ++  +     E    + N+  F  +I+FLQ ++  + +   ++      + +P+  ++LG N  D D  + +L + +      YVV L+++DC  +K  L+ +I  +    + +    + ++ ++ K +  ++D    W           ++ K+     +     ++LI++D+E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S    + L   L  LL +  FP ++S ++   + N +F+  D+SI + ++  Q  L +H  S                                SF +  E Q  +      TN   +         N+  YH     + R L +  S  P+  LG +  +++   L+  + +S E  S L+L++ L+ ++++ ++   F     S+EK+     + + +F+     L +     E  S S P  +  +     +++L E  ++ R + KQT F    +   N++   ++++L  P    L  +E ++     T R ++N + +  L   L+ P+ Y+ +++L+ +    I N  PD CI YK  ++  RLI L DW +AFA +V   E+ + +S   +    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   32 KGKNESEDSKLRFETYHLMWEQMKCETERLQEELNKNLFDSLIEFLQKSHTGFKKNSGDWGHQIKHREIPVAALVLGVNVTDHDLIFRSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMACCVDAKPKEKESIQVTQKMTHCSMDPLSSWYMTVTQKTHPKISGKKRTTSSKWQSPPVVLILKDMESFTTKILQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLPCKEHLTTVLDKLLLTAQFPFKISEKVLQILTN-IFLYHDFSIQNFVKGLQLSLLEHFYSQPLSVLCCSLPEAKRRINFLSAHQCENIRRLPSFRRYVEKQVSEKQVALLTNERFLKEETQSLLENLHVYHTNYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASALQLLRMLARDDLMTILQKCFKVFKSSSEKQLGSTAKRIEEFLAQFQSLDADAKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRTSKKQTRFEVLREKVVNFIDCLVREYLLPPETQPL--HEVVYFSAAHTLREHLNAAPRIALHTALNDPYFYIKNEALKSEE-GCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMESNSATTEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 712
[Close]
BLAST of origin recognition complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q9UBD5|ORC3_HUMAN (Origin recognition complex subunit 3 OS=Homo sapiens OX=9606 GN=ORC3 PE=1 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 8.341e-36
Identity = 159/675 (23.56%), Postives = 301/675 (44.59%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP-----KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPS-TDLT---ELNLPISSKS---SLIALDEW-----------LNSKEFFILKQ-----IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKEN-----CQILSDFMGNALKLASKVTTRESLSESIPVTIPNS------RRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y++I  +     E    + N+  F  +I+FLQ ++   FQ K   DL      + +P   ++LG N  D D T+ +L + +      YVV L+++DC  +K  L+ +I  ++    D+    E ++ ++ +    S+ +L  W           + SK+     Q     +++I++D+E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S  + L   L  LL +  FP +++ ++   + N +F+  D+S+ + I+  Q  L +H  S                                SF +  E Q+ +      TN   +         N+  YH     + R L    S  P+  LG +  +++   L+  + +S E  S L+L++ L+ +E++ +++       +  EN      + + +F+     L  +    E  S S P  +  +      +  L+ +  R + KQT F    ++  N++   ++++L  P    L  +E ++       R ++N + +  L   L+ P+ Y+ +++L+ +    I N  PD CI YK  ++  RLI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   43 RFETYQLIWQQMKSENERLQEELNKNLFDNLIEFLQKSHSG-FQ-KNSRDLGGQIKLREIPTAALVLGVNVTDHDLTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKEEESVHVTQRKTHYSMDSLSSWYMTVTQKTDPKMLSKKRTTSSQWQSPPVVVILKDMESFATKVLQDFIIISSQHLHEFPLILIFGIATSPIIIHRLLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTN-IFLYHDFSVQNFIKGLQLSLLEHFYSQPLSVLCCNLPEAKRRINFLSNNQCENIRRLPSFRRYVEKQASEKQVALLTNERYLKEETQLLLENLHVYHMNYFLVLRCLHKFTSSLPKYPLGRQIRELYCTCLEKNIWDSEEYASVLQLLRMLAKDELMTILEKCFKVFKSYCENHLGSTAKRIEEFLAQFQSL-DETKEEEDASGSQPKGLQKTDLYHLQKSLLEMKELRRSKKQTKFEVLRENVVNFIDCLVREYLLPPETQPL--HEVVYFSAAHALREHLNAAPRIALHTALNNPYYYLKNEALKSEE-GCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 710
[Close]
BLAST of origin recognition complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q9JK30|ORC3_MOUSE (Origin recognition complex subunit 3 OS=Mus musculus OX=10090 GN=Orc3 PE=1 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 1.273e-33
Identity = 152/670 (22.69%), Postives = 280/670 (41.79%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENWFQVKTEYDLP---KIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLK--------KVLECII----KSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQ----------IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPIINVRN---------YHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNL--SNEKE---NCQILSDFMGNALKLASKVTTRESLSESIPVTIPNS------RRNLKEQIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y ++        E    + NE  F  ++ FLQ ++  + +   ++      + +P   ++LG N  D D    +L + +      YVV L+++DC  +K        ++++C +    K +     L + N  + S  S  +        +  I K+          ++LI++ +E F  ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S    L + L  LL +  FP +LS +    + N +F+  D+SI   I+  +  L +H  S                                SF +  E Q +       TN   +  +          YH     + R L +  S  P+  LG +  +++   L+  + +S E +S L+L++ L+ +E+V ++      L  S EK+     Q + DF+     L +     E    S P  +  +      +  L+ +  R   K T F    ++  N++   ++ +L    +   +E ++     T R ++N + +  L   L+ P+ Y+ ++ L       I N  PD CI YK  ++   LI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   50 RFETYSLLWQRMKSETEQLQEELNENLFDNLVDFLQKSHPEFQKNSRDWGSQMKFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTSQLMDCCVDRHSKEVTSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRSPPVVLILKSMESFTSKVLQDFITISSQHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCVELFQSLSCEQHLTVVLDKLLLTPQFPFKLSKKALQVLTN-IFLYHDFSIQSFIKGIKLSLLEHFYSQPLSVLCCDLSEAKKRVNVFSVSQCENIRRLPSFRRYVENQPLGKQVALLTNETFLKEKTQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYKSALQLLRMLAKDELVSILQRCIEVLDSSTEKQLGNTTQKIKDFLTQFQNLDADSKEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRRTKKPTKFEMLRENVMNFIDNLVRDYLLPPESQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEELE----GCIPNTAPDICIAYKLHLECSLLINLVDWAEAFATVVTAAEKMDANSTVSEEMSEVIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 714
[Close]
BLAST of origin recognition complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q4R180|ORC3_RAT (Origin recognition complex subunit 3 OS=Rattus norvegicus OX=10116 GN=Orc3 PE=2 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 3.010e-33
Identity = 155/652 (23.77%), Postives = 285/652 (43.71%), Query Frame = 3 
Query:  132 NELSFGKIIQFLQI-------NYENWFQVKTEYDLPKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECI----IKSIIPSTDLTELNLPISSKSS--LIALDEW-----------LNSKEFFILKQ-----IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSIDYLELCSTNAPII---------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIV----QLVDFANTNLSNEKEN-CQILSDFMGNALKLASKVTTRESLSESIPVTIPNS-----RRNLKE--QIFRNANKQTHF---LQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPPAK----MTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            NE  F  ++ FLQ        N  NW    ++  L +I P   ++LG N  D D  + +L + +      YVV L+++DC  +K  L+ +    I   +      E N     ++S  + +L  W           + SK+     Q     ++LI++++E F+ ++LQ  I I+S    ++P +L+ G++++   +  +L +     +    F S S  + L + L  LL +  FP +LS +    + N +F+  D+SI + I+  +  L +H  S                                SF +  E Q ++      TN   +         ++  YH     + R L +  S  P+  LG +  +++   L+  + +S E +S L+L++ L+ +E++    Q V   N++   +  N  Q +  F+     L       E    S P  +  +     +++L E  ++ R   K T F    ++  N++   ++ +L        +E ++     T R ++N + +  L   L+ P+ Y+ +++L+ +    I +  PD CI YK  ++  RLI L DW +AFA +V   E+ D +S  ++    +   RF +AV ELE LGF+K  K K D +  LTWG 
Sbjct:   66 NENLFDNLVDFLQKSHSEFQKNSGNW---GSQMRLREI-PTAALILGVNVTDHDVIFRSLTETLHNNVTPYVVSLQAKDCPDVKHFLQKLTSELIDCCVDRNSKEEKNDKALRRTSYSMDSLSSWYSTVAQKTGPKMTSKKRATCSQWQSPPVVLILKNMESFSTKVLQDFIIISSQHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCIELFQSLSCKEHLTVVLDKLLLTPQFPFKLSKKALQVLTN-IFLYHDFSIQNFIKGLKLSLLEHFYSQPLSVLCCDLSEAKKRINVFSVNQCEKIRRLPSFRRYVENQPLEKQVALLTNETFLKEETQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYESALQLLRMLAKDELMGILEQCVKVLNSSTEKQLSNTAQKIKGFLTQFQNLDDS-KEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRRTTKKPTKFEMLRENVINFIDNLVRDYLLPPEGQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEALKSEE-GCIPSVAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKMDTNSTVSEEMSEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGG 710
[Close]
BLAST of origin recognition complex subunit 3 vs. TrEMBL
Match: A0A5N5N3P8 (Uncharacterized protein OS=Pangasianodon hypophthalmus OX=310915 GN=PHYPO_G00014640 PE=4 SV=1)

HSP 1 Score: 174.096 bits (440), Expect = 1.432e-42
Identity = 156/624 (25.00%), Postives = 287/624 (45.99%), Query Frame = 3 
Query:  225 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPST-----DLTELNLPISSKS---SLIALDEWLNS-----------------KEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHL-LSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSI-DYLELCSTNAPII--------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIV----QLVDFANTNLSNE-KENCQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIF------------RNANKQTHF---LQDFCNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQI---VEQKDPDSPP----AKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            +P   ++LG N PD D T+ +L D + E    + V +++++C +LK +++ +++ ++ +      D  + ++P+  K    S+ AL +W  +                  +F     I++I +D E FN  +LQ  I I S    + P + + G++++  ++  ML +     +    F S S +  L   +  L L+  FP +L+ ++   +V+ +F+  D+S+ + ++  Q  L +H +S                                SF +  E Q   + ++L +++  +         ++R YHK    I R L  L S  P+  LG +  ++    L+  +  + E +S ++L++ L+ +E+V    + VD   +  + + +   Q L D++    +L S   + E L+E   VT P      K  +F            R + K + F     +    +   ++ HL  P    L  YE  + +     R ++N + + +++  LS+PF Y+ + SL+ D+  ++SN  PD CI YK  ++  RLI L+DWL+A+A +    E KDPDS       ++   RF +AV ELEFLGFVK  K K D +  LTWG 
Sbjct:   99 IPTAALVLGVNVPDHDMTFQSLSDLLQESVTPFAVSVQAKECAALKNLMQRVLERLMGARVSVEDDEEDPSVPLPQKRVSCSMSALCQWYKTVTKKQTMKSPEKKCSSVNDFSETPPILVIFKDFEAFNPRVLQDFILICSRYIQELPLIFVFGIATSPSTIQHMLPHSVSSLLCIELFQSLSCTQHLATVIDKLILTSQFPFKLNGKVLQVLVS-IFLYHDFSVRNFVKGLQLALLEHFHSQPLSVLCCEKKEFLVYAQKLSHQDVEMIRQLPSFMRYVEAQDAQEQVQLLTSDEHVKVVCQKLLKDLRKYHKNYYPILRCLHTLTSSLPKYPLGKQIRELHISCLEKNVWETNEYESAMQLLRLLAKDELVTTLRKCVDILKSGKTKKMRSALQQLEDYLVKFEQLDS--MSVEDLNEE-EVTSPGKDLQKKTDLFQLQKTLLEMKGTRRSKKMSPFEVLRNEALGVIDGLVRSHLTPPELQPL--YEVCYYNSSGILRRHLNATPRTSIQTALSHPFYYLQNVSLKTDA-GTVSNAAPDICIAYKLHLECGRLINLFDWLEAYATVASAAEGKDPDSEEYGKVDELKHARFIQAVSELEFLGFVKSTKQKTDHVARLTWGG 715
[Close]
BLAST of origin recognition complex subunit 3 vs. TrEMBL
Match: A0A210QFR9 (Origin recognition complex subunit 3 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT06788 PE=4 SV=1)

HSP 1 Score: 173.326 bits (438), Expect = 2.825e-42
Identity = 159/671 (23.70%), Postives = 295/671 (43.96%), Query Frame = 3 
Query:   60 TRQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQINYENW-FQVKTEYDLPKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIP----------STDLTELNLPISSKSSLIALDEWLNSK-------------------EFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTH-LLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQH--------LNSPFHSFWKESELQSIDYLEL-------------CSTNAP-----------------IINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNE-----KENCQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQI------FRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSP-----PAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            T Q+++E +  E   +  +   K     F  +++F +  +  +    +T     K +P   ++ G NTPD    +  L   + E  +  V  L+S+DC ++K  L  ++  I+           S ++ + NLPIS    L  L +W + K                   +  IL  +I++ ED+E F   +LQ  I I S+  SQ P V + G++++V ++  +L N     +    F +   ++ L L +   L+++  P +L SR++  +++ +F+  D+S+ + I+  QF +  H        L  P      +++  + D LEL             CS                     +  +  Y +    I R L  L SK P+  LG +  +V+   L + +  + + Q +L+L+K +S +E++ L+    + L N+     K+    ++  +     L  +V   E  +   PV       +LK+++       +  +       +  ++     +++L    AL  +E L+ D   T R ++  S +  ++  L     Y+ +++   D+  +IS  +PD CI+YK  ++  +LI LYDWLQAF  +    D ++      P ++ Q RF +AV EL+FLGFVK  K K D +  LTWG 
Sbjct:   42 TYQSLWESVDTEIQILQSDLNTKI----FDDLLKFTKTCHSRFTLSSQTGDSRTKEIPTAALVTGVNTPDHGVMFATLVTLLQERVSPLVAILQSKDCNNVKNTLSKLLGQILKNPQLFEDDEDSPEVNQKNLPIS----LATLADWYDDKYTLNHSSPKKRKSEEGDLVDIQILPPVIMVFEDLESFQPRVLQEFITICSNYLSQLPIVFVFGIATSVSAVHRLLPNAVSSTLCMEKFQAPPSTEYLTLLINQILMTKHCPFKLGSRVFKLLLD-IFLYHDFSVLNFIKGLQFSMMDHFLSNPMSQLCCPLEELPNQTKRMNSDELELIRQLPSFMRYVESCSLERQAELLTDDAETKIEVLKLVTEIHTYREEFYPILRCLHTLVSKLPKQPLGKQLREVYATVLGWNMEENEDYQISLDLLKFMSKDELIGLLRGCGSCLGNDLPSSLKDIPVSINSLLDRFDTLHEQVEEDEEETTDSPVIQKTDLHSLKKRLQELEKKKKKLSPYEKLRTECVDYFDSLFRKYLVSPKALPLHELLYYDSASTVRSHLTASPRAAVQLALGSSHTYLRNQT-ESDNSGTISPDIPDVCIVYKLHMECSQLINLYDWLQAFITVKTSNDEENDDQVKNPDQVLQARFIRAVSELQFLGFVKPTKRKTDHVARLTWGG 702
[Close]
BLAST of origin recognition complex subunit 3 vs. TrEMBL
Match: A0A1S3I245 (origin recognition complex subunit 3-like OS=Lingula unguis OX=7574 GN=LOC106160311 PE=4 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 4.199e-42
Identity = 149/614 (24.27%), Postives = 276/614 (44.95%), Query Frame = 3 
Query:  225 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTE------LNL--------------------PISSKSSLIALDEWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGML-NNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLN-SPFHSFW-----KESELQSIDYLEL--------------------------------CSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNE-------------KENCQILSDFMGNALKLASKVTTRESLSESIP--VTIPNSRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMT---QCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            +P   ++ G N PD D  ++ L   + E    YV  L+S+DC ++K ++  ++  I+ + DL E      LN+                    P  SK   ++  E  NS   F    I++++ED+E F   ++Q  +   S+  ++ P VL++G+++AV ++  +L +  S +   + F A  S   L  +    +++     +L  +++  +++ +F+  D+S+ + I+  QF L  H   +P  +        E+ L ++   EL                                 +    + ++ +YH     +   L       P+   G +  +++  +L   + +S   + +  L++TLS +E++ ++     +LS               KE  Q   D     L  A+     ES S+S+P  + +   R+ L E+  +  +  T    D  N++ +  +Q+L        YE  + D+L   R ++N S +  ++  LS P+ Y+ ++SL  ++  +IS  LPD CI+YK  ++  RLI LYDWLQAFA +++    D  P ++    Q RF +AV EL+FLGF+K  K K D +  LTWG 
Sbjct:   81 VPTAALITGVNMPDHDLMFSNLVSLLQERVTPYVALLRSKDCGTMKNIMAKMMGLILGTKDLFEEDAEEQLNVKRVPPTLSVLASWYASKTTCPSPSKKKRMSGGEARNSGVLF--PPIVIVMEDLEGFPAHVVQDFVIACSNHLAELPIVLVLGIATAVTAVHRILPSTVSALLCIEKFQAPPSTEYLTQVISKVVMTARHHFKLGPKVFRLLLD-IFLYHDFSVLNYIRGLQFALMDHFYVNPLSALCCSKEKAEANLHALSAKELEEIRKAASFRLFVEGQPAKAQKQLLLDDKYLKSAVTELLADLYDYHAAYFPVLSCLFCFVRNLPKHPFGKQIRELYGTNLGTSVFDSEVYKDSFALLRTLSRDELLSILGKCIESLSETDVPTKLDSVTAKLKEFVQKFKDI--EDLPQATVEADAESNSDSLPKRMDMHTLRKTLLEKKKKKQSAYTILRHDVINYVDKLCRQYLKAPKLYPLYEIFYYDNLGEIRKHINGSPRIAVQTALSNPYHYLQNESLHCEA-GAISPSLPDICIVYKLHLECGRLINLYDWLQAFATVIQGDTDDDQPKQLNKEIQARFIRAVSELQFLGFIKPTKKKTDHVARLTWGG 688
[Close]
BLAST of origin recognition complex subunit 3 vs. TrEMBL
Match: W5UAE7 (Origin recognition complex subunit 3 OS=Ictalurus punctatus OX=7998 GN=ORC3 PE=2 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 6.320e-42
Identity = 158/624 (25.32%), Postives = 284/624 (45.51%), Query Frame = 3 
Query:  225 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPST-------DLTELNLPISSKS-SLIALDEWLNS-----------------KEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHL-LSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSI-DYLELCSTNAPII--------NVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIV----QLVDFANTNLSNEKENC-QILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIF------------RNANKQTHF---LQDFCNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQI---VEQKDPDSPP----AKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            +P   ++LG N PD D T+ +L D + E    + V +++++C +LK +++ +++ +I +        D    +LP    S S+ AL +W  +                  +F     I++I +D E FN  +LQ  I I S    + P + + G++++  ++  ML +     +    F S S +  L   +  L L+  FP +LS ++   +V+ +F+  D+S+ + ++  Q  L +H  S                                SF +  E Q   + ++L +++  +         ++R YHK+   I R L  L S  P+  LG +  +++   L+  +  + E +S ++L++ L+ +E+V    + VD   +  + +  +  Q L D++    +L S   + E L+E   V  P      K  +F            R + K + F     +    +   ++ HL  P    L  YE  +       R ++N + + +++  LS+PF Y+ + +L+ D+  ++SN  PD CI YK  ++  RLI LYDWL+A+A +    E KDPDS       ++   RF +AV ELEFLGFVK  K K D +  LTWG 
Sbjct:  101 IPTAALVLGVNVPDHDMTFQSLSDLLQESVTPFAVSVQAKECAALKNLMQRVLERLIGAGVSVEDDEDDPSSSLPQKRVSCSMSALCQWYKTVTKKQTVKLPGKKCSSVNDFSESPPILVIFKDFEAFNPRVLQDFILICSRYIQELPLIFVFGIATSPSTIQHMLPHSVSSLLCIELFQSLSCTQHLATVIDKLILTSQFPFKLSGKVLQVLVS-IFLYHDFSVRNFVKGLQLALLEHFYSQPLSVLCCEKKEFLVRAQKLSHQDVEMVRQLPSFMRYVEAQDTQEQVQLLTSDEHVKVVCQKLLKDLRKYHKSYYPIVRCLHTLTSSLPKYPLGKQIRELYISCLEKNVWETNEYESAIQLLRLLAKDELVTTLRKCVDILKSGKTKKMTSALQQLDDYLVKFEQLDS--MSVEDLNEE-EVMSPGKDLQKKTDLFQLQKTLLEMKSTRRSKKMSPFEVLRNEALGVIDGLVRSHLTPPEMQPL--YEVCYYSSSGVLRRHLNATPRTSIQTALSHPFYYLQNVNLKTDA-GTVSNAAPDICIAYKLHLECGRLINLYDWLEAYATVASAAEGKDPDSEEYGKVDQLKHARFIQAVSELEFLGFVKSTKQKTDHVARLTWGG 717
[Close]
BLAST of origin recognition complex subunit 3 vs. TrEMBL
Match: A0A3P8YB72 (Origin recognition complex, subunit 3 OS=Esox lucius OX=8010 PE=4 SV=1)

HSP 1 Score: 170.244 bits (430), Expect = 2.195e-41
Identity = 157/606 (25.91%), Postives = 278/606 (45.87%), Query Frame = 3 
Query:  225 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLK----KVLECIIKSII---------PSTDLTELNLPISSKSSLIALDEWLNSKEF------------FILKQ---IILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTH-LLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSP-----------------------------FHSFWKESELQSI-DYLELCSTNAPI--------INVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKENCQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFLQD-FCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIV---EQKDPDSPP----AKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            +P   ++LG N PD D T+ +L +++    + +VV L++++C +LK    KVLE ++ + +         P    T +NL      SL  L +W  +K +              ++Q   I++I +D+E+F+ ++LQ  I I S    Q P + + G+++A   +   L +     +    F S S +  L   +   +L+  FP +LS ++   +V+ +F+  D+S+ + I+  Q  L +H +S                                SF +  E Q   D +EL + +  +        I++  YHK    I R L  L S  P+  LG +  ++    L+  + ++ E  S + L++ ++ EE+V L+   +  L   K             L+L   +T     ++S+ + +  SRR  K   F         L+D    +    ++ HL    +   YE  +       R ++N + + +++  LS P+ Y+ ++SLR +   + S+  PD CI+YK  ++  RLI LYDWL+A+A +V   E KDP+S       ++   RF +AV ELEFLGF+K  K K D ++ LTWG 
Sbjct:   64 IPTAALVLGVNVPDHDMTFQSLSEQLQLSVSPFVVSLQAKECAALKNLIQKVLERLMGAGVWVNDEDQCEPEQGSTSVNLK-RVHCSLKTLHDWYKTKTYTSTPGEKRTSIGINVQQHPPIVVIFKDLEVFSPKVLQDFIIICSRYIEQLPLIFVFGIATAPSVIQHTLPHSVSSLLGIELFQSLSCTQHLATVIDQVILTSEFPFKLSGKVLQVLVS-IFLYHDFSVRNFIKGLQLALLEHFHSQPLSVLCCRKQEALGHISKLSHQDVERIQQLPSFMRYVEQQGPQDQVELLTNDDHVKEVCVKLLIDLHKYHKNHYPILRCLHVLTSSLPKYPLGKQIRELHISCLEKNVWDNEEYASAMTLLRMMAKEELVSLLQKCSVILKPGKTK-----KMRAVLLRLDDLIT---KFTKSL-LEMKESRRTKKMSQFE-------ILRDEVLEFFDSLVRCHLAPPESQPLYEVCYYSSSAVLRRHLNATPRTSIQTALSNPYHYLKNESLRTED-GTFSSAAPDICIVYKLHLECGRLINLYDWLEAYATVVSAAEGKDPESADYGKVDELKHARFIQAVSELEFLGFIKSTKQKTDHVSRLTWGG 650
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Cavefish
Match: orc3 (origin recognition complex subunit 3 [Source:NCBI gene;Acc:103029540])

HSP 1 Score: 159.844 bits (403), Expect = 4.388e-41
Identity = 150/626 (23.96%), Postives = 283/626 (45.21%), Query Frame = 3 
Query:  225 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIP-------STDLTELNLPISSKS-SLIALDEWLNS-----------------KEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHL-LSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNS--------------------------------PFHSFWKESELQSIDYL--------ELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIV----QLVDFANTNLSNE-KENCQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIFR--------NANKQTHFLQDF-------CNWLHEWLKQHL--PHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQI---VEQKDPDSPP----AKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            +P   ++LG N PD D T+ +L + + +    + V +++++C +LK +++ +++ ++          + T ++LP    S S+ AL +W  S                   F     II+I +D E FN  +LQ  I I +    + PF+ + G++++  ++  ML +     +    F S   +  L   +  L L+  FP +LSS++   +V+ +F+  D+S+ + ++  Q  L +H +S                                 F  + +  E Q   +L        E+C     + ++R YHK    + + L  L S  P+  LG +  ++    ++  +  + E +S ++L++ L+ +E+V    +  D    + + + K   Q L +++    +L S ++  +  +E   VT P      K  +F+           ++T  +  F         ++   ++ +L  P    L   E  +       R ++N + + +++  LS+PF Y+ ++SL+ D+  ++SN  PD CI YK  ++  RLI L+DWL+A+A +    E KDPDS       ++   RF +AV ELEFLGFVK  K K D +  LTWG 
Sbjct:  100 IPTAALVLGVNVPDHDVTFQSLSELLRKSVTPFAVSVQAKECAALKNLMQKVLERLMGVGVTLEDDEEDTGIHLPHKKVSCSVSALSQWYKSMMKTRAIKSPDKTGGSENGFSQSPPIIVIFKDFEAFNPRVLQDFILICNRYIQELPFIFIFGIATSPSTIQHMLPHSVSSLLCIELFQSLPCTQHLATVIDKLILTSQFPFKLSSKVLQVLVS-IFLYHDFSVRNFVKGLQLALLEHFHSQPLSVLCCGKNEALLYAQKLSHQDVEMVRQLPSFMRYVENQEPQEQVHLLTSDEGVREVCQRF--LKDLRKYHKNYYPVLKCLHSLTSSLPKYPLGKQIRELHIYCMEKNVWETNEYESAMQLLRLLAKDELVLSLRKCADILKPDKTKKMKSALQQLENYIAKFEQLDS-MSIEDLCAEE--VTSPGKDLQKKTDLFQLQKTLLEMKGTRRTKKISPFELLRNEALEFIDGLVRSYLTPPELQPL--NEVCYYSSSGVLRRHLNATPRTSIQTALSHPFYYLQNESLKTDA-GTVSNSAPDICIAYKLHLECGRLINLFDWLEAYATVTSAAEGKDPDSEDYGKVDELKHARFIQAVSELEFLGFVKSTKQKTDHVARLTWGG 716
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Sea Lamprey
Match: orc3 (origin recognition complex, subunit 3 [Source:ZFIN;Acc:ZDB-GENE-030131-6247])

HSP 1 Score: 147.517 bits (371), Expect = 1.328e-37
Identity = 160/693 (23.09%), Postives = 302/693 (43.58%), Query Frame = 3 
Query:   63 RQNIYEIILNEFMKIAENFYLKTNELSFGKIIQFLQI-------NYENWFQVKTEYDLPKIMPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIP-----------STDLTELNLPISS---KSSLIALDEWLNS----------------KEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNR--SLMRVSKHFFASASPSDLLNLFLTHLL-SEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQH--------LNSPFHSFWKESELQSIDYLELCST--NAP-------------------------------IINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKENCQI---LSDFMG-----NALKLASKVTTRESLS---ESIPVTIPNSRRNLKEQIF--RNANKQTHFLQDF-------CNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPA-------KMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            R   Y+ +  E    AE  +++ N   F K+I FL         N ++W + +   ++P        + G N  D +  +  L +++ E    ++V L+ ++C  LK+ ++ I+ +++            S DL +   P+S+     S  AL  W +S                        I++I+ ++E F   +LQ LI I S   ++ P VL++G++++  +L  +L +   SL+ V +  F +   ++LL+  L  LL ++ F  +L+ +    ++  +F+  D+S+ + ++  QF + +H        L  P  S   ++ ++S+   ELC     AP                               +  +  YH+    + R L     + P   LG +  +++   L+  +  S    S + L++ L+ +E+  L++     LS    + ++   ++   G     +AL    +    E ++   + +PV        L++ +   + A KQ      +        + L++ ++++L        +E  +  D  T + ++N S +  ++  L+ P+ Y+ +K+LR  +  SI+N  PD CI YK  ++   +I LYDWLQAF Q V Q   DS  A       + T  RF +AV EL+FLGFVK  K K D +  LTWG 
Sbjct:   13 RFETYQTLSQELKTSAEAVHVEMNAQVFEKMISFLSGARGVASDNLQSWAERQRSNEIPT----AAFVTGVNVADHEVVFQTLTERLRESVTPHIVSLQPKECRGLKQAVQKILGTLLGRQISCEDDEGESDDLGDRK-PLSAWRVLPSFSALCNWYSSLPQPVSDHVKGKRKVSGRHSTTPPIVIILRELESFPPRVLQDLIRICSQYVNRLPLVLVLGIATSPLALHRLLPHSVSSLLCVER--FQTPPATELLSSTLDQLLLTDRFLFKLNGKALQVLIG-IFLYHDFSVRNFVKGLQFAMMEHFYEQPLSVLCMPPSSL--KAHIKSLGP-ELCEAVRQAPSFRRYVEGRKASEQDRLLTDNEYLKTTVWILLSELHRYHRRFFLMLRGLHTFTHQLPGHPLGKQVRELYCSVLESPVWESEGYSSAMHLLRMLARDELCCLLESCVEQLSAAPTDPELQGAVTSLQGVLQGLHALGEPGEAPNVEEMALPAQKVPVLGKTDLHQLQKTLMEMQAAKKQQKKSTPYEVLRTKALDLLNDLVRKYLQPPEGQTLHEVSYFSDSSTLKQHLNASPRAAIQMALTNPYYYLQNKALR-STEGSITNMAPDLCIAYKLHLECGCMINLYDWLQAF-QTVLQAGKDSEEAETPHVIDQQTSARFIRAVSELQFLGFVKPTKRKTDHVARLTWGG 692
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Nematostella
Match: EDO40942 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5P8])

HSP 1 Score: 105.916 bits (263), Expect = 3.614e-24
Identity = 115/517 (22.24%), Postives = 219/517 (42.36%), Query Frame = 3 
Query:  483 FFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTH-LLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHL------------NSPFHSFWKESELQSID----------YLELCSTNAP-------IINVRN----YHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLK-YGLGNSIELQSNLELMKTLSYEEIVQLV--------DFANTNLSNEKENCQILSDFMGNALKLASKVTTRESL---------SESIPVTIPN-SRRNLKEQI-FRNANKQT------HFLQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMT------------QCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            F +   +++I ED E F   ++Q  I I S      P VL+ G++++V ++  +L +     +S   F S      L   ++  L++  +  +L ++++ ++  E F+  D+S+ +     QFC+ +H             ++      +E     +D          ++E C+           II + N    YH     I   L  + +  P   LG K   ++   L    + +  + +  L L++ L+ +E+V+L+         F  T L+ +K  C  L ++  N L+   +      +         S   P      +RR L   + F+ + ++          Q   +++    ++HL    +L  +E ++ D L   + ++    +  ++  LS P  Y+  +   +++  +I + LPD  + YK  ++  R+I LYDWLQAF  ++   DPD   +  T            Q RF +AV EL+F+GF+K  K K D +  LTWG 
Sbjct:    7 FLVSPAMVIIFEDFEGFPAHIVQDFITICSQYADHLPLVLVFGVATSVAAIHQVLPHSVSTLLSIQRFQSQPSLVCLQEIISQVLMTPKYSFKLGAKVFRFLY-ENFLFHDFSLQNFSTGLQFCILEHFYCNPASILCCPSSADREDIIRELTDDELDIIRSLLSFKRHVESCNKQQQAQLLTDIIIELLNGLDSYHWYFFPILDCLHAMAANLPRLPLGKKVRDLYEYSLSPTHIYHQDKYRDALALLRVLAKDELVELIIKCVNILEKFLETALNAKK--CPDLFNYKKNMLEFLEQFEKLSGMCKNNFHIVTSGQQPCQPGKEARRKLSTDLSFKRSTQKRKDTPYDQLRQKTVDYMDSLFRKHLRSPQSLPLHEVMYFDKLHKVKEHLIGMPRAAIQTALSDPRHYLKCECCEIEA-GAIQDSLPDVSVAYKLHLECSRMINLYDWLQAFKVVL---DPDPKASTKTPSKKQKKSDEQLQARFIRAVSELQFMGFIKPTKRKTDHVQRLTWGG 516
[Close]
BLAST of origin recognition complex subunit 3 vs. Ensembl Medaka
Match: orc3 (origin recognition complex subunit 3 [Source:NCBI gene;Acc:101168411])

HSP 1 Score: 157.918 bits (398), Expect = 2.120e-40
Identity = 156/630 (24.76%), Postives = 274/630 (43.49%), Query Frame = 3 
Query:  225 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLK----KVLECIIKSIIPSTDLTELN-----LPISSKSSLIALDEW--LNSK-----------------EFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTH-LLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHL------------NSPFH-----------------SFWKESELQSID-----------YLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIV----QLVDFANTNLSNEKEN-CQILSDFMGNALKLASKVTTRESLSESI---PVTIPN----------------SRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQK--DPDSPP----AKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGS 1817
            +P   ++LG N PD D T+++L D + +    YVV L++++C +LK    +VLE ++++++   D  E +     +  S   SL  L +W  + +K                 E   L  ++++ +D+E FN ++LQ  I I S    + P + + G++++  ++  ML +     +    F S S ++ L   +   +L+  FP +L+ ++ S +V+ +F   D+S+ + ++  Q  L +H              +  H                 SF +  E Q  +             E+C     I  +  YHK      R L  L S  P   LG +  ++    L+  +      QS ++L+K  + +E+V    +  +   +  S   +N C+ L + +    +L + V    S  E +   P  +P                 SRR+ K   F     +T    D     H W  +  P       +E  +   + T + ++N S + +++  LS P  Y+++ SL+ +   S+S+  PD CI YK  ++  RLI LYDWL+A+A +V     DPD        ++   RF +AV ELEFLGFVK  K K D +  LTWG 
Sbjct:   99 IPTAALMLGVNVPDHDLTFSSLSDLLRQSVTPYVVSLQAKECGALKHLLKRVLEGLMETVVAVDDEDEADQAACHVQKSVHCSLTTLCDWYIIKTKKSSNDTPGKKRPSTVTDEPEQLPPVVVVFKDLEAFNPKVLQDFILICSRYVHRLPLMFIFGIATSPSTIQHMLPHSVSSLLCIQLFQSLSCTEHLATVIDKFILTHQFPFKLTEKVLSVLVS-IFFFHDFSVRNFMKGLQLALLEHFYTQPLSVLCCRKKAALHHATQLDHGDLERIRLLPSFKRYVEGQEAEEQVNLMTDDSHLKEVC--QKLIKTLHKYHKNYYPTLRCLHALTSTLPRHLLGKQIRELHEACLRKNVWEQENYQSAMKLLKMQAKDELVVSLRRCAEILRSVKSKTMKNACEQLEELLCRFQQLDAAVDVAPSEDECVLSPPKNLPKKTDLFQLQKTLLEMNESRRSKKLSPFEILRNETVEFVDGLVRSHLWPPESQP------LHEVCYYSSVATVKHHLNASPRTSIQVALSNPDHYLENDSLKTED-GSLSSAAPDICIAYKLHLECGRLINLYDWLEAYATVVSAAKVDPDQDAFGKVDEVKHARFIRAVSELEFLGFVKSTKQKTDHVARLTWGG 718
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BLAST of origin recognition complex subunit 3 vs. Planmine SMEST
Match: SMESG000033631.1 (SMESG000033631.1)

HSP 1 Score: 1012.68 bits (2617), Expect = 0.000e+0
Identity = 501/533 (94.00%), Postives = 503/533 (94.37%), Query Frame = 3 
Query:  225 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQSIDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKENCQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGSVF 1823
            MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQSIDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLK GLGNSIELQSNLELMKTLS                           F GNALKL SKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELF+DDLETFRINMNPSV+ETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGSVF
Sbjct:    1 MPLGIMLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQSIDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKCGLGNSIELQSNLELMKTLS---------------------------FYGNALKLVSKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELFIDDLETFRINMNPSVRETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGSVF 506
[Close]
BLAST of origin recognition complex subunit 3 vs. Planmine SMEST
Match: SMESG000033631.1 (SMESG000033631.1)

HSP 1 Score: 1000.73 bits (2586), Expect = 0.000e+0
Identity = 496/528 (93.94%), Postives = 498/528 (94.32%), Query Frame = 3 
Query:  240 MLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQSIDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKENCQILSDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGSVF 1823
            MLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQSIDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLK GLGNSIELQSNLELMKTLS                           F GNALKL SKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELF+DDLETFRINMNPSV+ETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGSVF
Sbjct:    1 MLLGANTPDRDETYTALCDKIMEMTNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKSSLIALDEWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIGLSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQLSSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQSIDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVFTVHLKCGLGNSIELQSNLELMKTLS---------------------------FYGNALKLVSKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFLQDFCNWLHEWLKQHLPHYSALIGYEELFIDDLETFRINMNPSVRETLKKGLSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQAFAQIVEQKDPDSPPAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTWGSVF 501
The following BLAST results are available for this feature:
BLAST of origin recognition complex subunit 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ORC33.655e-3823.56origin recognition complex subunit 3 [Source:HGNC ... [more]
ORC31.737e-3623.56origin recognition complex subunit 3 [Source:HGNC ... [more]
ORC32.304e-2823.75origin recognition complex subunit 3 [Source:HGNC ... [more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of origin recognition complex subunit 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Orc36.989e-4025.27gene:FBgn0005654 transcript:FBtr0087768[more]
Orc36.989e-4025.27gene:FBgn0005654 transcript:FBtr0087769[more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
orc33.338e-4224.32origin recognition complex, subunit 3 [Source:ZFIN... [more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
orc34.606e-3725.98origin recognition complex subunit 3 [Source:NCBI ... [more]
orc36.853e-3624.73origin recognition complex subunit 3 [Source:NCBI ... [more]
orc37.078e-3624.73origin recognition complex subunit 3 [Source:NCBI ... [more]
orc38.508e-3524.35origin recognition complex subunit 3 [Source:NCBI ... [more]
orc33.148e-2924.49origin recognition complex subunit 3 [Source:NCBI ... [more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Orc31.820e-3422.69origin recognition complex, subunit 3 [Source:MGI ... [more]
Orc35.337e-3322.69origin recognition complex, subunit 3 [Source:MGI ... [more]
Orc35.241e-1023.95origin recognition complex, subunit 3 [Source:MGI ... [more]
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BLAST of origin recognition complex subunit 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q32PJ3|ORC3_BOVIN1.340e-3723.01Origin recognition complex subunit 3 OS=Bos taurus... [more]
sp|Q5DJU3|ORC3_SPECI4.664e-3622.34Origin recognition complex subunit 3 OS=Spermophil... [more]
sp|Q9UBD5|ORC3_HUMAN8.341e-3623.56Origin recognition complex subunit 3 OS=Homo sapie... [more]
sp|Q9JK30|ORC3_MOUSE1.273e-3322.69Origin recognition complex subunit 3 OS=Mus muscul... [more]
sp|Q4R180|ORC3_RAT3.010e-3323.77Origin recognition complex subunit 3 OS=Rattus nor... [more]
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BLAST of origin recognition complex subunit 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5N5N3P81.432e-4225.00Uncharacterized protein OS=Pangasianodon hypophtha... [more]
A0A210QFR92.825e-4223.70Origin recognition complex subunit 3 OS=Mizuhopect... [more]
A0A1S3I2454.199e-4224.27origin recognition complex subunit 3-like OS=Lingu... [more]
W5UAE76.320e-4225.32Origin recognition complex subunit 3 OS=Ictalurus ... [more]
A0A3P8YB722.195e-4125.91Origin recognition complex, subunit 3 OS=Esox luci... [more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
orc34.388e-4123.96origin recognition complex subunit 3 [Source:NCBI ... [more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
orc31.328e-3723.09origin recognition complex, subunit 3 [Source:ZFIN... [more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of origin recognition complex subunit 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO409423.614e-2422.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of origin recognition complex subunit 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
orc32.120e-4024.76origin recognition complex subunit 3 [Source:NCBI ... [more]
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BLAST of origin recognition complex subunit 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000033631.10.000e+094.00SMESG000033631.1[more]
SMESG000033631.10.000e+093.94SMESG000033631.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031477 ID=SMED30031477|Name=origin recognition complex subunit 3|organism=Schmidtea mediterranea sexual|type=transcript|length=1871bp
TATAAAATTGAATGGAATACAAAATTTTTAAAAAAAATAGGCAGCATCAT
GATATTTGTACTCGACAAAATATCTATGAAATTATACTCAATGAATTTAT
GAAAATAGCTGAAAATTTTTATTTGAAAACAAACGAATTATCATTTGGGA
AGATTATTCAATTTCTACAAATAAATTATGAAAATTGGTTTCAAGTTAAA
ACCGAATATGATTTACCGAAAATAATGCCACTCGGTATCATGTTGTTGGG
TGCTAATACTCCTGATCGTGATGAAACATATACTGCCTTATGTGATAAGA
TTATGGAAATGACTAATAGCTATGTTGTAAAATTAAAATCCCGTGATTGC
ACTTCACTTAAAAAGGTATTGGAATGCATAATAAAGTCAATAATTCCTTC
TACAGATTTAACAGAATTGAATTTACCCATTTCTTCAAAGAGTTCATTGA
TAGCACTTGACGAGTGGTTGAACAGTAAAGAATTCTTTATTTTGAAACAA
ATTATTTTGATTGTTGAAGATATTGAATTATTTAATGTGGAATTGTTGCA
GAGCTTAATCGAAATTACCAGTTCAAGAAATTCCCAATATCCCTTCGTAC
TATTGATCGGCCTCTCGTCTGCTGTCGAATCTCTCGATGGGATGCTTAAT
AACCGATCATTAATGCGCGTTTCCAAGCACTTCTTTGCTTCAGCCAGCCC
TTCCGACTTGTTGAATCTCTTTCTAACTCATTTGCTATCAGAAGGGTTCC
CGATCCAATTGAGCAGCCGATTATATTCATACATTGTCAACGAAATGTTC
ATGTGTTGCGATTATTCCATTTCCCATTTGATTCAGCGATATCAGTTCTG
CCTTTTTCAGCATTTGAATAGCCCATTTCATTCCTTTTGGAAGGAATCAG
AACTCCAATCCATCGACTACTTGGAACTGTGCTCAACGAATGCGCCGATA
ATTAATGTAAGAAATTACCATAAAACATCCGTATTTATCTGCCGCTGGTT
GCTGGACTTGTTTTCGAAATTTCCCGAATCCAAACTAGGATCAAAATTTC
ATCAAGTGTTTACGGTTCATCTGAAATACGGGCTTGGAAATTCTATAGAG
TTGCAATCAAATCTTGAATTGATGAAGACGTTATCGTACGAAGAAATAGT
TCAATTAGTCGATTTCGCTAATACAAATTTATCCAATGAAAAAGAAAACT
GCCAAATTTTATCAGATTTTATGGGGAATGCATTAAAATTGGCCTCCAAG
GTAACGACTAGAGAATCATTGTCCGAGTCAATTCCTGTAACTATTCCAAA
TAGTAGGAGAAATCTGAAAGAACAAATATTCAGGAATGCCAATAAGCAGA
CGCATTTTTTACAGGATTTCTGCAATTGGCTGCATGAGTGGTTGAAACAG
CACCTGCCACACTATTCCGCACTTATTGGTTATGAAGAACTTTTCATGGA
TGATTTGGAAACATTCCGAATCAATATGAATCCATCCGTTAAGGAAACTT
TGAAAAAAGGCCTTTCATATCCATTTGCCTATGTTGACGATAAAAGTTTG
CGACTCGATTCCTTGGAATCAATCAGCAACAAGCTGCCTGATACTTGCAT
TCTGTATAAGCAGCTCATTGATTTCCCTCGATTGATTTATCTTTATGATT
GGCTGCAGGCGTTTGCTCAAATAGTAGAACAAAAAGATCCCGATTCACCT
CCAGCAAAAATGACCCAGTGTAGATTTAACAAGGCCGTTATGGAATTGGA
ATTTTTAGGTTTTGTAAAACGAGTAAAATCCAAGGTCGATGTAATGAATA
ATCTAACGTGGGGCTCTGTGTTTTAGATGTGTTGTATTGCTGAAATATAT
TAGCCAATAATTGAAAAAAAA
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protein sequence of SMED30031477-orf-1

>SMED30031477-orf-1 ID=SMED30031477-orf-1|Name=SMED30031477-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=605bp
MEYKIFKKNRQHHDICTRQNIYEIILNEFMKIAENFYLKTNELSFGKIIQ
FLQINYENWFQVKTEYDLPKIMPLGIMLLGANTPDRDETYTALCDKIMEM
TNSYVVKLKSRDCTSLKKVLECIIKSIIPSTDLTELNLPISSKSSLIALD
EWLNSKEFFILKQIILIVEDIELFNVELLQSLIEITSSRNSQYPFVLLIG
LSSAVESLDGMLNNRSLMRVSKHFFASASPSDLLNLFLTHLLSEGFPIQL
SSRLYSYIVNEMFMCCDYSISHLIQRYQFCLFQHLNSPFHSFWKESELQS
IDYLELCSTNAPIINVRNYHKTSVFICRWLLDLFSKFPESKLGSKFHQVF
TVHLKYGLGNSIELQSNLELMKTLSYEEIVQLVDFANTNLSNEKENCQIL
SDFMGNALKLASKVTTRESLSESIPVTIPNSRRNLKEQIFRNANKQTHFL
QDFCNWLHEWLKQHLPHYSALIGYEELFMDDLETFRINMNPSVKETLKKG
LSYPFAYVDDKSLRLDSLESISNKLPDTCILYKQLIDFPRLIYLYDWLQA
FAQIVEQKDPDSPPAKMTQCRFNKAVMELEFLGFVKRVKSKVDVMNNLTW
GSVF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000420parapharyngeal region
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR020795ORC3
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003688DNA replication origin binding
Vocabulary: biological process
TermDefinition
GO:0006260DNA replication
GO:0006267pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006270DNA replication initiation
Vocabulary: cellular component
TermDefinition
GO:0005664nuclear origin of replication recognition complex
GO:0000784nuclear chromosome, telomeric region
GO:0005634nucleus
GO:0005656nuclear pre-replicative complex
GO:0031261DNA replication preinitiation complex