Propionyl-CoA carboxylase alpha chain, mitochondrial

Query:  166 HDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +DP E  F KIL+ANRGEIACR+I +CK+ GIK VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+T A+AVHPGYGFLSEN  FA+ L   +VVF+GP++ AI +MGDKIESK +A  A+V+ IPG+DG + D +EA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++LS  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++ ETR+AMGEQAV +A+AV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHP++E ITG+D+V +M RV KG+PL  KQ+DI +NGWAVECRVYAEDPYKSFGLPS+GRL+ Y+EPLHLP VR DSGIQ GS+ISIYYDPMI KL+TYG DR++AL  M  ALD+YVIRGVTHNI LLR+++   RFV G+I+T +L +VYPDGFKG  LT  E   L A+++ +FV  ++R + F +  R  +I       + D+++   W LS+    +  DK   V  S   + S F+V  + G+   + + ++LA  +++ ++D  +  +Q +SR   G ++ Q++GT YK+ + + +  +L+KFML K   DTSSV+ +PMPG+V  VSVK G  V++GQE+CV+EAMKMQNSM A K G +K+VH Q G TV +GD+++ELE
Sbjct:   56 YDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPDGFKGHMLTKSEKNQLLAIASSLFVAFQLRAQHFQENSRMPVI-------KPDIAN---WELSV----KLHDKVHTVVAS--NNGSVFSVEVD-GSKLNVTSTWNLASPLLSVSVDGTQRTVQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE 728          

Query:  187 FKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            F KIL+ANRGEIACR+I +CK+ GIK VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+T A+AVHPGYGFLSEN  FA+ L   +VVF+GP++ AI +MGDKIESK +A  A+V+ IPG+DG + D +EA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++LS  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++ ETR+AMGEQAV +A+AV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHP++E ITG+D+V +M RV KG+PL  KQ+DI +NGWAVECRVYAEDPYKSFGLPS+GRL+ Y+EPLHLP VR DSGIQ GS+ISIYYDPMI KL+TYG DR++AL  M  ALD+YVIRGVTHNI LLR+++   RFV G+I+T +L +VYPDGFKG  LT  E   L A+++ +FV  ++R + F +  R  +I       + D+++   W LS+    +  DK   V  S   + S F+V  + G+   + + ++LA  +++ ++D  +  +Q +SR   G ++ Q++GT YK+ + + +  +L+KFML K   DTSSV+ +PMPG+V  VSVK G  V++GQE+CV+EAMKMQNSM A K G +K+VH Q G TV +GD+++ELE
Sbjct:   37 FDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPDGFKGHMLTKSEKNQLLAIASSLFVAFQLRAQHFQENSRMPVI-------KPDIAN---WELSV----KLHDKVHTVVAS--NNGSVFSVEVD-GSKLNVTSTWNLASPLLSVSVDGTQRTVQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE 702          

Query:  166 HDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +DP E  F KIL+ANRGEIACR+I +CK+ GIK VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+T A+AVHPGYGFLSEN  FA+ L   +VVF+GP++ AI +MGDKIESK +A  A+V+ IPG+DG + D +EA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++LS  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++ ETR+AMGEQAV +A+AV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHP++E ITG+D+V +M RV KG+PL  KQ+DI +NGWAVECRVYAEDPYKSFGLPS+GRL+ Y+EPLHLP VR DSGIQ GS+ISIYYDPMI KL+TYG DR++AL  M  ALD+YVIRGVTHNI LLR+++   RFV G+I+T +L +VYPDGFKG  LT  E   L A+++ +FV  ++R + F +  R  +I       + D+++   W LS+    +  DK   V  S   + S F+V  + G+   + + ++LA  +++ ++D  +  +Q +SR   G ++ Q++GT                                                V++GQE+CV+EAMKMQNSM A K G +K+VH Q G TV +GD+++ELE
Sbjct:   56 YDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPDGFKGHMLTKSEKNQLLAIASSLFVAFQLRAQHFQENSRMPVI-------KPDIAN---WELSV----KLHDKVHTVVAS--NNGSVFSVEVD-GSKLNVTSTWNLASPLLSVSVDGTQRTVQCLSREAGGNMSIQFLGTV-----------------------------------------------VAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE 681          

Query:  166 HDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLP 1281
            +DP E  F KIL+ANRGEIACR+I +CK+ GIK VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+T A+AVHPGYGFLSEN  FA+ L   +VVF+GP++ AI +MGDKIESK +A  A+V+ IPG+DG + D +EA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++LS  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++ ETR+AMGEQAV +A+AV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHP++E ITG+D+V +M RV KG+PL  KQ+DI +NGWAVECRVYAEDPYKSFGLPS+GRL+ Y+EPLHLP
Sbjct:   16 YDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLP 387          

Query:  193 KILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKI-ANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKV---ESIIGHKLSK-------FMLPKKVVDTSSV-----IIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            K+LIANRGEIACR++ + K+ G++ VAV+S+ D  S  V MADEA  IGPA +  SYL+MEKI+   K + A+A+HPG GFLSEN  FA+  +   ++F+GP   AI  MG K  SK I  AA V  + GY GE + +D+ +K  A +IGYPVMIKA  GGGGKGMRI  +++E  E  + +R EAK SF DD MLIEK+++ PRH+E+Q+  D HGNA+YL ER+CS+QRR+QK+IEEAP+  I  E RK +GE AV+ AKAV Y  AGTVEF++D K NF F+EMNTRLQVEHP++E+ITG D+V    R+  G  + L Q +I++ G A E R+YAEDP  +F +P  G L     P   P+ R ++G+++G E+S++YDPMI KLV +  DR  AL  +  +L  Y I G+  NI  L ++   P F +GN+ T+++P+ +      ++   KE+    A+   + +K +    TF  +         S S R         ++S +  +  +D   NV ++V       T N +   S +I       DK         +++  L S     Y+     G   K K+   E+ I +  SK         +PK +   SS       +APM G ++ V VK G +V  G  L V+ AMKM++++ + K G +K V ++ G   +    ++E E
Sbjct:   51 KVLIANRGEIACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGE-DQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNF-MPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALG--LILKEKAMTDTFTLQAHDQFSPFSSSSGR-------RLNISYTRNMTLKDGKNNVAIAV-------TYNHDGSYSMQIE------DKTF-------QVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTI-YLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFE 715          

Query:  139 ARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFL--KKDRSLLIAEKSESFRGDLSHP-EEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
             + IY     D  E KF KILIANRGEIACR+I + +  GIK VAVHSDVD+ S  V+MADEA+C+G A T+ SYL  ++IL AV+ TGA+AVHPGYGFLSENT FA +LE     F+GPNSKAI  MGDKI SK+IA AA+V  IPGYDGEI D D  +K++  IGYPVMIKASAGGGGKGMR+AWNDK+A EGY+LS+ EA SSFGDDRML+EK+I+ PRHIE+Q++CDKHGNAL+LNERECSIQRRNQKVIEEAPS+F+ PE R+ MGEQAVQ+AKAVGYDSAGTVEFLVD +RNFYFLEMNTRLQVEHPI+E ITG+DIV QM RV  GHPL + Q  + +NGWA E RVYAEDPYK FGLPSVGRL+ Y EP H+  VRCDSGI+EGSEISIYYDP+ICKLVT+G++R +AL  M +ALD+YVIRGVTHNIPLLRDIV E RF +G+ITT YLPEVYP+GF+G  L+PKE  ++ A ++ +  +   R   FL   K RS  +A  S++++   S P +E      H +E +       V    +++   +    G +  I+ + +L+  + +  +D + I  Q++ +  +G IT  Y GT +K+KV      K  ++M  K  VD S+V+++PMPG +K V+VK G  VS+GQEL V+EAMKMQNS+ A K G +KAV+ + G TV +G++++ELE
Sbjct:   33 GKEIYTTVGIDYNEPKFDKILIANRGEIACRVIKTARAMGIKTVAVHSDVDSNSLHVKMADEAVCVGEAPTAKSYLRADRILQAVEDTGAQAVHPGYGFLSENTKFAAELEKAGAKFIGPNSKAILDMGDKIHSKKIATAARVSMIPGYDGEIADEDMCVKVSRDIGYPVMIKASAGGGGKGMRVAWNDKQAREGYRLSKQEAASSFGDDRMLVEKFIDNPRHIEMQVLCDKHGNALWLNERECSIQRRNQKVIEEAPSSFVPPEMRRKMGEQAVQLAKAVGYDSAGTVEFLVDSQRNFYFLEMNTRLQVEHPITECITGIDIVQQMLRVSYGHPLPITQEQVPLNGWAFESRVYAEDPYKGFGLPSVGRLSRYVEPKHVDGVRCDSGIREGSEISIYYDPLICKLVTHGDNREQALNRMQEALDNYVIRGVTHNIPLLRDIVQEKRFRTGDITTKYLPEVYPEGFQGTSLSPKEQDVVIAFASALNARKLARANQFLNQNKQRSTHVASFSKTYKFVSSLPVKEGERPTEHAVEVE------FVEGSANKAQVRIG---GKTVTISGDLNLSHPVNSIEVDGEHITTQIVGKR-AGEITVLYKGTPFKVKVLPEQAVKYLQYMKEKAKVDLSTVVLSPMPGAIKNVNVKPGDMVSEGQELVVMEAMKMQNSLHAGKTGRVKAVNVKVGATVDEGEVLVELE 724          

Query:  139 ARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFL--KKDRSLLIAEKSESFRGDLSHP-EEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
             + IY     D  E KF KILIANRGEIACR+I + +  GIK VAVHSDVD+ S  V+MADEA+C+G A T+ SYL  ++IL AV+ TGA+AVHPGYGFLSENT FA +LE     F+GPNSKAI  MGDKI SK+IA AA+V  IPGYDGEI D D  +K++  IGYPVMIKASAGGGGKGMR+AWNDK+A EGY+LS+ EA SSFGDDRML+EK+I+ PRHIE+Q++CDKHGNAL+LNERECSIQRRNQKVIEEAPS+F+ PE R+ MGEQAVQ+AKAVGYDSAGTVEFLVD +RNFYFLEMNTRLQVEHPI+E ITG+DIV QM RV  GHPL + Q  + +NGWA E RVYAEDPYK FGLPSVGRL+ Y EP H+  VRCDSGI+EGSEISIYYDP+ICKLVT+G++R +AL  M +ALD+YVIRGVTHNIPLLRDIV E RF +G+ITT YLPEVYP+GF+G  L+PKE  ++ A ++ +  +   R   FL   K RS  +A  S++++   S P +E      H +E +       V    +++   +    G +  I+ + +L+  + +  +D + I  Q++ +  +G IT  Y GT +K+KV      K  ++M  K  VD S+V+++PMPG +K V+VK G  VS+GQEL V+EAMKMQNS+ A K G +KAV+ + G TV +G++++ELE
Sbjct:   33 GKEIYTTVGIDYNEPKFDKILIANRGEIACRVIKTARAMGIKTVAVHSDVDSNSLHVKMADEAVCVGEAPTAKSYLRADRILQAVEDTGAQAVHPGYGFLSENTKFAAELEKAGAKFIGPNSKAILDMGDKIHSKKIATAARVSMIPGYDGEIADEDMCVKVSRDIGYPVMIKASAGGGGKGMRVAWNDKQAREGYRLSKQEAASSFGDDRMLVEKFIDNPRHIEMQVLCDKHGNALWLNERECSIQRRNQKVIEEAPSSFVPPEMRRKMGEQAVQLAKAVGYDSAGTVEFLVDSQRNFYFLEMNTRLQVEHPITECITGIDIVQQMLRVSYGHPLPITQEQVPLNGWAFESRVYAEDPYKGFGLPSVGRLSRYVEPKHVDGVRCDSGIREGSEISIYYDPLICKLVTHGDNREQALNRMQEALDNYVIRGVTHNIPLLRDIVQEKRFRTGDITTKYLPEVYPEGFQGTSLSPKEQDVVIAFASALNARKLARANQFLNQNKQRSTHVASFSKTYKFVSSLPVKEGERPTEHAVEVE------FVEGSANKAQVRIG---GKTVTISGDLNLSHPVNSIEVDGEHITTQIVGKR-AGEITVLYKGTPFKVKVLPEQAVKYLQYMKEKAKVDLSTVVLSPMPGAIKNVNVKPGDMVSEGQELVVMEAMKMQNSLHAGKTGRVKAVNVKVGATVDEGEVLVELE 724          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDR-SHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPK--KVVDT------SSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIEL 2232
            +++L+ANRGEIA R+ N+ ++ GI+ VAV SD D  S FV+ AD+A  IGP   + SYLNM+KI+++  ++GA+A+HPGYGFLSEN  FA+K     +VF+GP ++AI  MG K  SK+I   AKV  + G+ GE        K + +IGYPVM+KA  GGGGKGMRIAWN+ E  E    +R EAK SFG+D ML+EK++ KPRH+E+Q+  D HGN ++L ER+CS+QRR+QK+IEEAP+  +  +TR  +GE AV+ A AVGY  AGTVEF++D +  FYF+EMNTRLQVEHP+SE ITG D+V    RV +G  L LKQS+I +NG A ECRVYAED  K   +P+ GRL     P    + R D+G+  G E+SI+YDPMI K+V +G+DR+ A A +  AL    I G+  NI  +R ++  P F +GN+ T+++P+   + F   + TP E          ++V++ + +     +     + +    FR +LS    +            K     VS+ FD  S  TV+++ GNS+       L + I +    + +  L+   R +S  +  + +G    +      G   +++  P+  +  D+      S   +APMPG+++ + VK G++V+ GQ L V+ AMKM+  + A +   ++ +  Q G+ V    ++++ 
Sbjct:   20 QRVLVANRGEIAIRVQNTARKMGIETVAVFSDADRNSLFVKKADKAYHIGPPLAAESYLNMDKIINSALRSGAQAIHPGYGFLSENAGFAEKCAQAGLVFIGPPAQAIRDMGAKNVSKQIMEDAKVPVVKGFHGEDQSDANLKKKSAEIGYPVMLKAVYGGGGKGMRIAWNEAEFEEKLASARNEAKKSFGNDEMLVEKFVEKPRHVEVQVFGDHHGNYVHLWERDCSVQRRHQKIIEEAPAPNMEHDTRVKLGESAVRAAAAVGYVGAGTVEFIMDPRGEFYFMEMNTRLQVEHPVSEAITGTDLVEWQLRVAQGEKLPLKQSEIPLNGHAFECRVYAEDTRKGAFMPTAGRLNYVDFP---EDARIDTGVVSGDEVSIHYDPMIAKVVVWGQDRAVAAAKLESALARTRISGLPTNIDFVRRVLAHPEFAAGNVYTDFIPDHQKELFAESE-TPAE----------IYVESAVAHALAALQKSDAGVFQNLSFFRMNLSPKYIF------------KIDGKDVSIRFDSDSRLTVSYD-GNSYET-----LLNDIESTTDGSFKFTLEANGRRWSTVV--KNLGNSLMVN-----GVGQNEYETPQIHETFDSLSGGAASHSAVAPMPGIIEKILVKPGEQVTTGQALVVMTAMKMEYIIRAPEDSTVEHIKCQAGKNVPKNAVLVQF 670          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDR-SHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPK--KVVDT------SSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIEL 2232
            +++L+ANRGEIA R+ N+ ++ GI+ VAV SD D  S FV+ AD+A  IGP   + SYLNM+KI+++  ++GA+A+HPGYGFLSEN  FA+K     +VF+GP ++AI  MG K  SK+I   AKV  + G+ GE        K + +IGYPVM+KA  GGGGKGMRIAWN+ E  E    +R EAK SFG+D ML+EK++ KPRH+E+Q+  D HGN ++L ER+CS+QRR+QK+IEEAP+  +  +TR  +GE AV+ A AVGY  AGTVEF++D +  FYF+EMNTRLQVEHP+SE ITG D+V    RV +G  L LKQS+I +NG A ECRVYAED  K   +P+ GRL     P    + R D+G+  G E+SI+YDPMI K+V +G+DR+ A A +  AL    I G+  NI  +R ++  P F +GN+ T+++P+   + F   + TP E          ++V++ + +     +     + +    FR +LS    +            K     VS+ FD  S  TV+++ GNS+       L + I +    + +  L+   R +S  +  + +G    +      G   +++  P+  +  D+      S   +APMPG+++ + VK G++V+ GQ L V+ AMKM+  + A +   ++ +  Q G+ V    ++++ 
Sbjct:   20 QRVLVANRGEIAIRVQNTARKMGIETVAVFSDADRNSLFVKKADKAYHIGPPLAAESYLNMDKIINSALRSGAQAIHPGYGFLSENAGFAEKCAQAGLVFIGPPAQAIRDMGAKNVSKQIMEDAKVPVVKGFHGEDQSDANLKKKSAEIGYPVMLKAVYGGGGKGMRIAWNEAEFEEKLASARNEAKKSFGNDEMLVEKFVEKPRHVEVQVFGDHHGNYVHLWERDCSVQRRHQKIIEEAPAPNMEHDTRVKLGESAVRAAAAVGYVGAGTVEFIMDPRGEFYFMEMNTRLQVEHPVSEAITGTDLVEWQLRVAQGEKLPLKQSEIPLNGHAFECRVYAEDTRKGAFMPTAGRLNYVDFP---EDARIDTGVVSGDEVSIHYDPMIAKVVVWGQDRAVAAAKLESALARTRISGLPTNIDFVRRVLAHPEFAAGNVYTDFIPDHQKELFAESE-TPAE----------IYVESAVAHALAALQKSDAGVFQNLSFFRMNLSPKYIF------------KIDGKDVSIRFDSDSRLTVSYD-GNSYET-----LLNDIESTTDGSFKFTLEANGRRWSTVV--KNLGNSLMVN-----GVGQNEYETPQIHETFDSLSGGAASHSAVAPMPGIIEKILVKPGEQVTTGQALVVMTAMKMEYIIRAPEDSTVEHIKCQAGKNVPKNAVLVQF 670          

Query:  151 YWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHP---LLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAV 1593
            Y N    P+E  F K+++ANRGEIA R+  +       +VA++++ D  S     ADEA  +G     ++ YL +++I++   +   +A+HPGYGFLSE + FA   ++  +VF+GP+   +  MGDK+ +++ A  A V  +PG  G I   DEA++ A Q G P+++KA+ GGGG+G+R     +E  E ++ S +EA+++FGD  + +EK++ +PRHIE+Q++ D HGN ++L ER+CS+QRR+QKV+E AP+  +    R+ +   A+++A+ VGY +AGTVEFLVD K N+YF+E+N RLQVEH ++E ITGVD+V    R+ +G     L L Q  I   G A++CRV  EDP K F  P  GR+  ++    +  +R DS     GS IS +YD ++ K++    +   A A M++AL  + IRGV  NIP L +++ +P F+  ++ T ++ E +P+ F+ K    +   LL  +  V
Sbjct:   22 YANGVIKPRE--FNKVMVANRGEIAIRVFRALTELNKTSVAIYAEQDKNSMHRLKADEAYLVGKGLPPVAAYLTIDQIIETALKHNIDAIHPGYGFLSERSDFAAACQNAGIVFIGPSPDVMARMGDKVAARQAAIEAGVQVVPGTPGPITTADEAVEFAKQYGTPIILKAAYGGGGRGIRRVDKLEEVEEAFRRSYSEAQAAFGDGSLFVEKFVERPRHIEVQLLGDHHGNIVHLYERDCSVQRRHQKVVEIAPAPALPEGVREKILADALRLARHVGYQNAGTVEFLVDQKGNYYFIEVNARLQVEHTVTEEITGVDLVQAQIRIAEGKSLDDLKLSQETIQTTGSAIQCRVTTEDPAKGFQ-PDSGRIEVFRSGEGM-GIRLDSASAFAGSVISPHYDSLMVKVIASARNHPNAAAKMIRALKKFRIRGVKTNIPFLLNVLRQPSFLDASVDTYFIDE-HPELFQFKPSQNRAQKLLNYLGEV 502          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            P+ +      I APMPG V  + +K G +V+  Q L VL AMKM+  + +  AG +KA+H   G   S GD+++E+E
Sbjct: 1098 PRALPGVRGHIGAPMPGDVLELKIKEGDKVTKKQPLFVLSAMKMEMVIDSPIAGTVKAIHAPQGTKCSAGDLVVEVE 1174          

Query:  172 PKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAI-KIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVD-DKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEI----RNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVN-----------FESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIII 2226
            PK     KILI+NRGEIACR+I + ++ G++ VAV SD D  S   Q+ADE+  +G A +S SYL  E+ILD  K++GA+A+HPGYGFLSE+  FA+  +   ++F+GP S AI  MG K  SK I  AA V  I GY G+ + +DE + + A++IG+P+MIKA  GGGGKGMRIA    + +     +R E++ SFGD  +L+E+Y+  PRH+E+Q+  D++G+A+YL ER+CS+QRR+QK+IEEAP+  ++ + R+ +GE AV+ AKAVGY  AGTVEF++D +  +F+F+EMNTRLQVEHPI+E+ITG D+V    R+  G PL LKQS+I+  G A E R+YAE+P   F LP  G L     P    NVR ++G++EG E+S++YDPMI KLV +GE+R++AL ++V  L  Y I G+  NI  L D+ + P F   N+ T ++ E +   F    ++P++     + +A+  V NE+    RN     KD+   +A  +            + L   + L++ +K  +V V  D +     V+            + G+  +I  N +    + T N   D   + L S   SG + F+    K+     S  G +L             S I+APMPG+++ V VK G +V  G+ L VL AMKM++ + A K   IK++    G  V+ G  +I
Sbjct:   22 PKVRPISKILISNRGEIACRVIRTARKLGVRTVAVFSDPDEKSMHTQLADESYRVGEAASSASYLRGERILDIAKRSGAQAIHPGYGFLSESVEFAELCQREGIIFMGPPSSAIRDMGIKSTSKAIMAAAGVPIINGYHGD-DQSDECLQREADKIGFPLMIKAVRGGGGKGMRIAEKPDDFLTALNSARTESEKSFGDSSVLLERYVRSPRHVEVQVFADQYGDAVYLWERDCSVQRRHQKIIEEAPAPGLSEDLRRELGEAAVRAAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQVEHPITEMITGTDLVEWQIRIAAGEPLPLKQSEITRRGHAFEARIYAENPRGGF-LPGAGPLRYLSTPQPSNNVRVETGVREGDEVSVHYDPMIAKLVVWGENRTQALNSLVARLGEYHISGLDTNINFLIDLASHPEFQLANVHTGFIDEQFDTLFPPIIISPQQV----SQAALALVLNELQAAFRNGN---KDQDPFVATPNARL--------NYSLVRRYDLKANEKVYSVAVKFDGEDMQIQVDNGDWQDAKVERVQDGSRLKIRANIN--SNVTTYNASIDGTSVSLFSE--SGKVDFEVGQPKFL----SAQGDQLGA---------VGSRIVAPMPGILEKVLVKPGDKVKKGENLAVLIAMKMEHILKAPKDATIKSIGGAAGDNVAKGAAVI 689          

Query:  172 PKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAI-KIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVD-DKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEI----RNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVN-----------FESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIII 2226
            PK     KILI+NRGEIACR+I + ++ G++ VAV SD D  S   Q+ADE+  +G A +S SYL  E+ILD  K++GA+A+HPGYGFLSE+  FA+  +   ++F+GP S AI  MG K  SK I  AA V  I GY G+ + +DE + + A++IG+P+MIKA  GGGGKGMRIA    + +     +R E++ SFGD  +L+E+Y+  PRH+E+Q+  D++G+A+YL ER+CS+QRR+QK+IEEAP+  ++ + R+ +GE AV+ AKAVGY  AGTVEF++D +  +F+F+EMNTRLQVEHPI+E+ITG D+V    R+  G PL LKQS+I+  G A E R+YAE+P   F LP  G L     P    NVR ++G++EG E+S++YDPMI KLV +GE+R++AL ++V  L  Y I G+  NI  L D+ + P F   N+ T ++ E +   F    ++P++     + +A+  V NE+    RN     KD+   +A  +            + L   + L++ +K  +V V  D +     V+            + G+  +I  N +    + T N   D   + L S   SG + F+    K+     S  G +L             S I+APMPG+++ V VK G +V  G+ L VL AMKM++ + A K   IK++    G  V+ G  +I
Sbjct:   22 PKVRPISKILISNRGEIACRVIRTARKLGVRTVAVFSDPDEKSMHTQLADESYRVGEAASSASYLRGERILDIAKRSGAQAIHPGYGFLSESVEFAELCQREGIIFMGPPSSAIRDMGIKSTSKAIMAAAGVPIINGYHGD-DQSDECLQREADKIGFPLMIKAVRGGGGKGMRIAEKPDDFLTALNSARTESEKSFGDSSVLLERYVRSPRHVEVQVFADQYGDAVYLWERDCSVQRRHQKIIEEAPAPGLSEDLRRELGEAAVRAAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQVEHPITEMITGTDLVEWQIRIAAGEPLPLKQSEITRRGHAFEARIYAENPRGGF-LPGAGPLRYLSTPQPSNNVRVETGVREGDEVSVHYDPMIAKLVVWGENRTQALNSLVARLGEYHISGLDTNINFLIDLASHPEFQLANVHTGFIDEQFDTLFPPIIISPQQV----SQAALALVLNELQAAFRNGN---KDQDPFVATPNARL--------NYSLVRRYDLKANEKVYSVAVKFDGEDMQIQVDNGDWQDAKVERVQDGSRLKIRANIN--SNVTTYNASIDGTSVSLFSE--SGKVDFEVGQPKFL----SAQGDQLGA---------VGSRIVAPMPGILEKVLVKPGDKVKKGENLAVLIAMKMEHILKAPKDATIKSIGGAAGDNVAKGAAVI 689          

Query:  307 VQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAI-KIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVD-DKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEI----RNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVN-----------FESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIII 2226
             Q+ADE+  +G A +S SYL  E+ILD  K++GA+A+HPGYGFLSE+  FA+  +   ++F+GP S AI  MG K  SK I  AA V  I GY G+ + +DE + + A++IG+P+MIKA  GGGGKGMRIA    + +     +R E++ SFGD  +L+E+Y+  PRH+E+Q+  D++G+A+YL ER+CS+QRR+QK+IEEAP+  ++ + R+ +GE AV+ AKAVGY  AGTVEF++D +  +F+F+EMNTRLQVEHPI+E+ITG D+V    R+  G PL LKQS+I+  G A E R+YAE+P   F LP  G L     P    NVR ++G++EG E+S++YDPMI KLV +GE+R++AL ++V  L  Y I G+  NI  L D+ + P F   N+ T ++ E +   F    ++P++     + +A+  V NE+    RN     KD+   +A  +            + L   + L++ +K  +V V  D +     V+            + G+  +I  N +    + T N   D   + L S   SG + F+    K+     S  G +L             S I+APMPG+++ V VK G +V  G+ L VL AMKM++ + A K   IK++    G  V+ G  +I
Sbjct:    3 TQLADESYRVGEAASSASYLRGERILDIAKRSGAQAIHPGYGFLSESVEFAELCQREGIIFMGPPSSAIRDMGIKSTSKAIMAAAGVPIINGYHGD-DQSDECLQREADKIGFPLMIKAVRGGGGKGMRIAEKPDDFLTALNSARTESEKSFGDSSVLLERYVRSPRHVEVQVFADQYGDAVYLWERDCSVQRRHQKIIEEAPAPGLSEDLRRELGEAAVRAAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQVEHPITEMITGTDLVEWQIRIAAGEPLPLKQSEITRRGHAFEARIYAENPRGGF-LPGAGPLRYLSTPQPSNNVRVETGVREGDEVSVHYDPMIAKLVVWGENRTQALNSLVARLGEYHISGLDTNINFLIDLASHPEFQLANVHTGFIDEQFDTLFPPIIISPQQV----SQAALALVLNELQAAFRNGN---KDQDPFVATPNARLN--------YSLVRRYDLKANEKVYSVAVKFDGEDMQIQVDNGDWQDAKVERVQDGSRLKIRANIN--SNVTTYNASIDGTSVSLFSE--SGKVDFEVGQPKFL----SAQGDQLGA---------VGSRIVAPMPGILEKVLVKPGDKVKKGENLAVLIAMKMEHILKAPKDATIKSIGGAAGDNVAKGAAVI 625          

Query:  307 VQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAI-KIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVD-DKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEI----RNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVN-----------FESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIII 2226
             Q+ADE+  +G A +S SYL  E+ILD  K++GA+A+HPGYGFLSE+  FA+  +   ++F+GP S AI  MG K  SK I  AA V  I GY G+ + +DE + + A++IG+P+MIKA  GGGGKGMRIA    + +     +R E++ SFGD  +L+E+Y+  PRH+E+Q+  D++G+A+YL ER+CS+QRR+QK+IEEAP+  ++ + R+ +GE AV+ AKAVGY  AGTVEF++D +  +F+F+EMNTRLQVEHPI+E+ITG D+V    R+  G PL LKQS+I+  G A E R+YAE+P   F LP  G L     P    NVR ++G++EG E+S++YDPMI KLV +GE+R++AL ++V  L  Y I G+  NI  L D+ + P F   N+ T ++ E +   F    ++P++     + +A+  V NE+    RN     KD+   +A  +            + L   + L++ +K  +V V  D +     V+            + G+  +I  N +    + T N   D   + L S   SG + F+    K+     S  G +L             S I+APMPG+++ V VK G +V  G+ L VL AMKM++ + A K   IK++    G  V+ G  +I
Sbjct:    3 TQLADESYRVGEAASSASYLRGERILDIAKRSGAQAIHPGYGFLSESVEFAELCQREGIIFMGPPSSAIRDMGIKSTSKAIMAAAGVPIINGYHGD-DQSDECLQREADKIGFPLMIKAVRGGGGKGMRIAEKPDDFLTALNSARTESEKSFGDSSVLLERYVRSPRHVEVQVFADQYGDAVYLWERDCSVQRRHQKIIEEAPAPGLSEDLRRELGEAAVRAAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQVEHPITEMITGTDLVEWQIRIAAGEPLPLKQSEITRRGHAFEARIYAENPRGGF-LPGAGPLRYLSTPQPSNNVRVETGVREGDEVSVHYDPMIAKLVVWGENRTQALNSLVARLGEYHISGLDTNINFLIDLASHPEFQLANVHTGFIDEQFDTLFPPIIISPQQV----SQAALALVLNELQAAFRNGN---KDQDPFVATPNARLN--------YSLVRRYDLKANEKVYSVAVKFDGEDMQIQVDNGDWQDAKVERVQDGSRLKIRANIN--SNVTTYNASIDGTSVSLFSE--SGKVDFEVGQPKFL----SAQGDQLGA---------VGSRIVAPMPGILEKVLVKPGDKVKKGENLAVLIAMKMEHILKAPKDATIKSIGGAAGDNVAKGAAVI 625          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSL-SYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSG-IQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVV 1596
            + +L+ANRGEIA R+  +C   GIK+VAV+S+ D +    Q ADE+  +G     + +YLN+ +++   K+   +AVHPGYGFLSE + FA+ + D  + F+GP+ + +  MGDK+ ++  A  A V  +PG DG +   +EA++   + G PV+ KA+ GGGG+GMR+    ++  E ++ + +EAK++FG+  M IEK+I +PRHIE+Q++ DK GN ++L ER+CS+QRR+QKV+E AP+  +  E R  M E AV++A+ VGY++AGTVEFL D+  NFYF+E+N RLQVEH ++E ITG+D+V    RV +G  L      Q  I   G+A++CRV  EDP   F  P+ GRL  ++    +  +R DS     G+ IS YYD ++ K++++  D   + + M +AL  + IRGV  NIP L +++   +F+ G + T ++ E +P  FK K    +   LL  M  V+
Sbjct:   40 RSVLVANRGEIAIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKGLPPVEAYLNIPELIRVCKENDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGDKVAARVAAIEAGVPIVPGTDGPVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESFQRASSEAKAAFGNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQKVVEIAPAPRLPIEIRDKMTEAAVRLARHVGYENAGTVEFLCDESGNFYFIEVNARLQVEHTVTEEITGIDLVQSQIRVAEGMTLPELGYTQDKIVPRGYAIQCRVTTEDPANDFQ-PNTGRLEVFRSGEGM-GIRLDSASAYAGAIISPYYDSLLVKVISHASDLQSSASKMNRALREFRIRGVKTNIPFLLNVLENQKFLHGVLDTYFIDE-HPQLFKFKPSLNRAQKLLNYMGEVL 510          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            PK      S + APMPG V  + VKVG +V  GQ L VL AMKM+  + +  AGV+K +    G  +   D+I+ +E
Sbjct: 1105 PKANKSNKSEVGAPMPGTVIDIRVKVGDKVEKGQPLVVLSAMKMEMVVQSPLAGVVKKLEIANGTKLEGEDLIMIIE 1181          

Query:  169 DPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDR-SLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVH-VSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +P +  F KILIANRGEIACR+I +C++ GIK VAVHSDVD+ +  V+MADEA+C+GPA TS SYLNM+ I++A+K TGA+AVHPGYGFLSEN  FAK+L    V F+GP++ AI +MGDKIESK IA AAKV+ IPG+DG + D +EA+KIA +IGYPVMIKASAGGGGKGMRIAWND+E  EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++P+TR+ MGEQAV +AKAV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITG+D+V QM R+ KG+ L  KQSDI +NGWA+E RVYAEDPYKSFGLPS+GRL+ Y+EPL L NVR DSGIQEGS+ISIYYDPMI KLVTYG+ R +AL  M +ALD+YV+RGVTHNIPLLR+I+  PRFVSG+I+T +LPEVYPDGFKG  LT  E   L A +A ++   ++R++ FL   R S + AE S           +W L +   LE     ++VH + V    + +TV  + G   +++  ++LA  +++  I+     LQ +SR  +G I  QY+GT +KL+V S +   LSK M  K   DTSS++ +PMPG V  VSVK G  V++GQE+CV+EAMKMQNSM AAK   +K+VH + G TV +GD+++ELE
Sbjct:   50 EPNDKTFDKILIANRGEIACRVIKTCRKMGIKTVAVHSDVDSSAVHVKMADEAVCVGPAPTSKSYLNMDAIMNAIKLTGAQAVHPGYGFLSENKEFAKRLAAEGVTFIGPDTHAIQAMGDKIESKLIAKAAKVNTIPGFDGVVKDAEEAVKIAGEIGYPVMIKASAGGGGKGMRIAWNDEETREGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPDTRRKMGEQAVSLAKAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGLDLVEQMIRIAKGNKLQHKQSDIPINGWAIESRVYAEDPYKSFGLPSIGRLSQYQEPLDLDNVRVDSGIQEGSDISIYYDPMISKLVTYGKTREEALKKMEEALDNYVVRGVTHNIPLLREIIVHPRFVSGDISTKFLPEVYPDGFKGHMLTAGERQELLATAAALYTAAQLRSQRFLGDLRVSCVPAESS-----------DWELCVE--LE-----KSVHMLGVSRSGNKYTVEID-GEKVQVSGEWNLASALLSVTINGKHRTLQCLSRTAAGEIILQYLGTSFKLRVLSKLAASLSKHMPEKVPEDTSSILRSPMPGSVVAVSVKPGDTVAEGQEICVIEAMKMQNSMTAAKTAKVKSVHCKAGDTVGEGDLLVELE 721          

Query:  166 HDPKETKFKKILIANRGEIACR----------IINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDR-SLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVH-VSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            HD K   FK+      G I CR          +I +C++ GIK VAVHSDVD+ +  V+MADEA+C+GPA TS SYLNM+ I++A+K TGA+AVHPGYGFLSEN  FAK+L    V F+GP++ AI +MGDKIESK IA AAKV+ IPG+DG + D +EA+KIA +IGYPVMIKASAGGGGKGMRIAWND+E  EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++P+TR+ MGEQAV +AKAV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITG+D+V QM R+ KG+ L  KQSDI +NGWA+E RVYAEDPYKSFGLPS+GRL+ Y+EPL L NVR DSGIQEGS+ISIYYDPMI KLVTYG+ R +AL  M +ALD+YV+RGVTHNIPLLR+I+  PRFVSG+I+T +LPEVYPDGFKG  LT  E   L A +A ++   ++R++ FL   R S + AE S           +W L +   LE     ++VH + V    + +TV  + G   +++  ++LA  +++  I+     LQ +SR  +G I  QY+GT +KL+V S +   LSK M  K   DTSS++ +PMPG V  VSVK G  V++GQE+CV+EAMKMQNSM AAK   +K+VH + G TV +GD+++ELE
Sbjct:   15 HDVKHVCFKQ----RCGVIICRYSTVIEPNDKVIKTCRKMGIKTVAVHSDVDSSAVHVKMADEAVCVGPAPTSKSYLNMDAIMNAIKLTGAQAVHPGYGFLSENKEFAKRLAAEGVTFIGPDTHAIQAMGDKIESKLIAKAAKVNTIPGFDGVVKDAEEAVKIAGEIGYPVMIKASAGGGGKGMRIAWNDEETREGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPDTRRKMGEQAVSLAKAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGLDLVEQMIRIAKGNKLQHKQSDIPINGWAIESRVYAEDPYKSFGLPSIGRLSQYQEPLDLDNVRVDSGIQEGSDISIYYDPMISKLVTYGKTREEALKKMEEALDNYVVRGVTHNIPLLREIIVHPRFVSGDISTKFLPEVYPDGFKGHMLTAGERQELLATAAALYTAAQLRSQRFLGDLRVSCVPAESS-----------DWELCVE--LE-----KSVHMLGVSRSGNKYTVEID-GEKVQVSGEWNLASALLSVTINGKHRTLQCLSRTAAGEIILQYLGTSFKLRVLSKLAASLSKHMPEKVPEDTSSILRSPMPGSVVAVSVKPGDTVAEGQEICVIEAMKMQNSMTAAKTAKVKSVHCKAGDTVGEGDLLVELE 693          

Query:  184 KFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNS-FRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            + +K++IANRGEIACR++ + ++ G+++VAV+SD D  S  V MADEA  IGPA +  SYL M+KILD  K++ A+AVHPGYGFLSENT FA++ +   ++F+GP S AI  MG K  SK I +AA V  I GY G+          A +IGYPVMIKA  GGGGKGMRIA ++ E  E  + +R EA+ SF DD MLIEK++  PRH+E+Q+  D++G+A+YL ER+CS+QRR+QK+IEEAP   I+PE R+ +GE AV+ AKAV Y  AGTVEF++D + NFYF+EMNTRLQVEHP+SE+ITG D+V    RV  G  L L Q  I + G + E R+YAEDP  +F LP  G L     P    N R ++G++EG E+S +YDPMI KLV +GEDRS AL  +   L  Y I G+  NI  L  +   P F +GN+ T+++P+ Y   F   Q     +G +   +A+  +  E +     ++  S + +  + S    L+  +  ++S+  G         V VS+ ++    T + E+G   F ++    L   +       + ++      +    +        + ++  + +   + KF+            +APM G ++ V VK G  V  G  L V+ AMKM++++ A KAGVIK V F+ G   S    ++E++
Sbjct:   35 RIEKVVIANRGEIACRVMRTARKMGVRSVAVYSDADRHSMHVAMADEAYHIGPAASQQSYLCMDKILDVAKKSSAQAVHPGYGFLSENTEFAEQCKQEGIIFIGPPSSAIRDMGIKSTSKHIMSAAGVPIIEGYHGDDQSDARLQSEAARIGYPVMIKAVRGGGGKGMRIAQSEAEFHEQLESARREARKSFNDDVMLIEKFVENPRHVEVQVFGDQYGDAVYLFERDCSVQRRHQKIIEEAPGPGISPEVRRKLGEAAVRAAKAVNYVGAGTVEFIMDAQHNFYFMEMNTRLQVEHPVSEMITGTDLVEWQLRVAAGEKLPLSQEQIELRGHSFEARIYAEDPNNNF-LPGAGPLLHLSTPPGDHNTRIETGVREGDEVSAHYDPMIAKLVVWGEDRSAALKKLRYCLRQYNIVGLNTNIDFLLSLSGHPEFEAGNVHTSFIPQHYDHLFPPAQ---SPSGEVICQAALGLLLREKQQTQKYREQTSDVFSPFASSNGRRLNVLQCRNMSLQLG------DNKVAVSITYNPDG-TYSMETGGRVFAVSGELQLEGDVTYLCCSVNGVL------SRPKLVILDNTVHLFSMEGSAQVDVPVPKFLAGVSGSSAQGGAVAPMTGTIEKVLVKAGDSVQKGDPLMVMIAMKMEHTIRAPKAGVIKKVFFKEGSQASRHAALVEMQ 702          

Query:  184 KFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNS-FRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            + +K++IANRGEIACR++ + ++ G+++VAV+SD D  S  V MADEA  IGPA +  SYL M+KILD  K++ A+AVHPGYGFLSENT FA++ +   ++F+GP S AI  MG K  SK I +AA V  I GY G+          A +IGYPVMIKA  GGGGKGMRIA ++ E  E  + +R EA+ SF DD MLIEK++  PRH+E+Q+  D++G+A+YL ER+CS+QRR+QK+IEEAP   I+PE R+ +GE AV+ AKAV Y  AGTVEF++D + NFYF+EMNTRLQVEHP+SE+ITG D+V    RV  G  L L Q  I + G + E R+YAEDP  +F LP  G L     P    N R ++G++EG E+S +YDPMI KLV +GEDRS AL  +   L  Y I G+  NI  L  +   P F +GN+ T+++P+ Y   F   Q     +G +   +A+  +  E +     ++  S + +  + S    L+  +  ++S+  G         V VS+ ++    T + E+G   F ++    L   +       + ++      +    +        + ++  + +   +  F+            +APM G ++ V VK G  V  G  L V+ AMKM++++ A KAGVIK V F+ G   S    ++E++
Sbjct:   35 RIEKVVIANRGEIACRVMRTARKMGVRSVAVYSDADRHSMHVAMADEAYHIGPAASQQSYLCMDKILDVAKKSSAQAVHPGYGFLSENTEFAEQCKQEGIIFIGPPSSAIRDMGIKSTSKHIMSAAGVPIIEGYHGDDQSDARLQSEAARIGYPVMIKAVRGGGGKGMRIAQSEAEFHEQLESARREARKSFNDDVMLIEKFVENPRHVEVQVFGDQYGDAVYLFERDCSVQRRHQKIIEEAPGPGISPEVRRKLGEAAVRAAKAVNYVGAGTVEFIMDAQHNFYFMEMNTRLQVEHPVSEMITGTDLVEWQLRVAAGEKLPLSQEQIELRGHSFEARIYAEDPNNNF-LPGAGPLLHLSTPPGDHNTRIETGVREGDEVSAHYDPMIAKLVVWGEDRSAALKKLRYCLRQYNIVGLNTNIDFLLSLSGHPEFEAGNVHTSFIPQHYDHLFPPAQ---SPSGEVICQAALGLLLREKQQTQKYREQTSDVFSPFASSNGRRLNVLQCRNMSLQLG------DNKVAVSITYNPDG-TYSMETGGRVFAVSGELQLEGDVTYLCCSVNGVL------SRPKLVILDNTVHLFSMEGSAQVDVPVPMFLAGVSGSSAQGGAVAPMTGTIEKVLVKAGDSVQKGDPLMVMIAMKMEHTIRAPKAGVIKKVFFKEGSQASRHAALVEMQ 702          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPE 1518
            KK+++ANRGEIA R+  +C   GI+ VAV+S+ D      Q ADEA  IG     ++ YL++  I+   K    +A+HPGYGFLSE   FA+   D  V F+GP    +  MGDK++++ IA +A V  +PG D  I+   EA + +N  G+P++ KA+ GGGG+GMR+    +E  E Y+ + +EA ++FG+  + +EK+I KPRHIE+QI+ DK+GN ++L ER+CSIQRR+QKV+E AP+T ++P  R  +   +V +A+ VGY++AGTVEFLVD     YF+E+N+RLQVEH ++E IT VD+VH   RV +G  L    LKQ  I +NG+A++CRV  EDP + F  P  GRL  ++    +  +R DS    +G+ IS +YD ++ K++  G+D   A A M +AL  + +RGV  NIP L+++++  +F++G + T ++ E
Sbjct:   40 KKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGKGLPPVAAYLHIPDIIKVAKANDVDAIHPGYGFLSERADFAQACVDAGVRFIGPTPDVVRKMGDKVQARAIAISAGVPVVPGTDAPISCLQEAQEFSNSYGFPIIFKAAYGGGGRGMRVVREYEELEENYQRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDKYGNVIHLYERDCSIQRRHQKVVEIAPATQLDPHLRDRLTADSVNLARQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQLRVCEGRSLPELGLKQDKIRINGYAIQCRVTTEDPARGFQ-PDTGRLEVFRSGEGM-GIRLDSASAFQGAVISPHYDSLLVKVIASGKDLPAASAKMSRALAEFRVRGVKTNIPFLQNVLSNNQFLNGTVDTQFIDE 485          

Query: 1924 ITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIEL 2232
            + F+  G    + V+  +  K   F  PK + D    I APMPG V  V VK GQ+V  GQ LCVL AMKM+  + +  +G +  ++     T+   D+I+E+
Sbjct: 1078 VFFELNGQLRSVLVKDTVAMKEMHFH-PKALKDVRGQIGAPMPGKVVEVKVKQGQQVEKGQPLCVLSAMKMETVVNSPISGTVAKIYVTADSTLEGDDLILEI 1179          

Query:  148 IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            + ++  HDP E  F KILIANRGEIACR+I +C++ GIK VAVHSDVD+ S  V+MADEA+C+GPA TS SYLNM+ I+DA+K TGA+AVHPGYGFLSEN  FA++L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++PETR+AMGEQAV +AKAV Y SAGTVEFLVD K+NF+FLEMNTRLQVEHPI+E ITG+D+V +M RV KG+ L  KQ+DIS+NGWA+ECRVYAEDPYKSFGLPS+GRL+ Y+EP  LP VR DSGIQEGS+ISI+YDPMI KLVT+G DR++AL  M  ALD+YVIRGVTHNIPLL +I+T P FV G+ITT +LPEVYPDGFKG  L+ +E   L   +A ++V  + R+  FL   R  +      S          W LS+    +   K+ +V VS   D   F+V  + G +  +++ ++L+  +++ +  + +  +Q +SR+ +G ++ Q+MGT YKL+V +    +LSK+M  K   DTSS++ +PMPG V TVSVK G  VS+GQE+CV+EAMKMQNSM AAK   +K++H +PG+TV +GD++++LE
Sbjct:   45 VQYSTAHDPNEKTFDKILIANRGEIACRVIKTCRKMGIKTVAVHSDVDSASVHVKMADEAVCVGPAPTSKSYLNMDAIMDAIKHTGAQAVHPGYGFLSENKEFARRLAAESVTFIGPDTHAIQAMGDKIESKLLAKNAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETREGFRFSAQEAASSFGDDRLLIEKFIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPETRRAMGEQAVALAKAVKYSSAGTVEFLVDSKKNFFFLEMNTRLQVEHPITECITGLDLVQEMIRVAKGYSLKHKQADISINGWAIECRVYAEDPYKSFGLPSIGRLSQYQEPHLLPGVRVDSGIQEGSDISIFYDPMISKLVTHGRDRTEALKRMEDALDNYVIRGVTHNIPLLHEIITHPLFVKGDITTKFLPEVYPDGFKGHTLSQEEQNELIGTAASIYVALQRRSHRFLSNTRVPIAKNDVNS----------WDLSV----QLDGKSYSVQVSRINDT--FSVEID-GTTLNVSSEWNLSSSLLSVSFGDAQKTIQCLSRDAAGNLSIQFMGTVYKLQVLTSHAAELSKYMPEKVEEDTSSILRSPMPGTVVTVSVKPGDMVSEGQEICVIEAMKMQNSMTAAKTAKVKSLHVKPGETVGEGDLLVQLE 723          

Query:  148 IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            + ++  HDP E  F KILIANRGEIACR+I +C++ GIK VAVHSDVD+ S  V+MADEA+C+GPA TS SYLNM+ I+DA+K TGA+AVHPGYGFLSEN  FA++L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++PETR+AMGEQAV +AKAV Y SAGTVEFLVD K+NF+FLEMNTRLQVEHPI+E ITG+D+V +M RV KG+ L  KQ+DIS+NGWA+ECRVYAEDPYKSFGLPS+GRL+ Y+EP  LP VR DSGIQEGS+ISI+YDPMI KLVT+G DR++AL  M  ALD+YVIRGVTHNIPLL +I+T P FV G+ITT +LPEVYPDGFKG  L+ +E   L   +A ++V  + R+  FL   R  +      S          W LS+    +   K+ +V VS   D   F+V  + G +  +++ ++L+  +++ +  + +  +Q +SR+ +G ++ Q+MGT YKL+V +    +LSK+M  K   DTSS++ +PMPG V TVSVK G  VS+GQE+CV+EAMKMQNSM AAK   +K++H +PG+TV +GD++++LE
Sbjct:   32 VQYSTAHDPNEKTFDKILIANRGEIACRVIKTCRKMGIKTVAVHSDVDSASVHVKMADEAVCVGPAPTSKSYLNMDAIMDAIKHTGAQAVHPGYGFLSENKEFARRLAAESVTFIGPDTHAIQAMGDKIESKLLAKNAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETREGFRFSAQEAASSFGDDRLLIEKFIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPETRRAMGEQAVALAKAVKYSSAGTVEFLVDSKKNFFFLEMNTRLQVEHPITECITGLDLVQEMIRVAKGYSLKHKQADISINGWAIECRVYAEDPYKSFGLPSIGRLSQYQEPHLLPGVRVDSGIQEGSDISIFYDPMISKLVTHGRDRTEALKRMEDALDNYVIRGVTHNIPLLHEIITHPLFVKGDITTKFLPEVYPDGFKGHTLSQEEQNELIGTAASIYVALQRRSHRFLSNTRVPIAKNDVNS----------WDLSV----QLDGKSYSVQVSRINDT--FSVEID-GTTLNVSSEWNLSSSLLSVSFGDAQKTIQCLSRDAAGNLSIQFMGTVYKLQVLTSHAAELSKYMPEKVEEDTSSILRSPMPGTVVTVSVKPGDMVSEGQEICVIEAMKMQNSMTAAKTAKVKSLHVKPGETVGEGDLLVQLE 710          

Query:  232 IINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDR 1644
            +I +C++ GIK VAVHSDVD+ S  V+MADEA+C+GPA TS SYLNM+ I+DA+K TGA+AVHPGYGFLSEN  FA++L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++PETR+AMGEQAV +AKAV Y SAGTVEFLVD K+NF+FLEMNTRLQVEHPI+E ITG+D+V +M RV KG+ L  KQ+DIS+NGWA+ECRVYAEDPYKSFGLPS+GRL+ Y+EP  LP VR DSGIQEGS+ISI+YDPMI KLVT+G DR++AL  M  ALD+YVIRGVTHNIPLL +I+T P FV G+ITT +LPEVYPDGFKG  L+ +E   L   +A ++V  + R+  FL   R
Sbjct:   35 VIKTCRKMGIKTVAVHSDVDSASVHVKMADEAVCVGPAPTSKSYLNMDAIMDAIKHTGAQAVHPGYGFLSENKEFARRLAAESVTFIGPDTHAIQAMGDKIESKLLAKNAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETREGFRFSAQEAASSFGDDRLLIEKFIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPETRRAMGEQAVALAKAVKYSSAGTVEFLVDSKKNFFFLEMNTRLQVEHPITECITGLDLVQEMIRVAKGYSLKHKQADISINGWAIECRVYAEDPYKSFGLPSIGRLSQYQEPHLLPGVRVDSGIQEGSDISIFYDPMISKLVTHGRDRTEALKRMEDALDNYVIRGVTHNIPLLHEIITHPLFVKGDITTKFLPEVYPDGFKGHTLSQEEQNELIGTAASIYVALQRRSHRFLSNTR 505          

Query: 1945 TKY--KLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAG 2166
            T+Y   LK+ +    +LSK+M  K   DTSS++ +PMPG V TVSVK G  VS+GQE+CV+EAMKMQNSM AAK  
Sbjct:  504 TRYVPSLKILTSHAAELSKYMPEKVEEDTSSILRSPMPGTVVTVSVKPGDMVSEGQEICVIEAMKMQNSMTAAKTA 579          

Query:  229 RIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKG 1542
            ++I +C++ GIK VAVHSDVD+ S  V+MADEA+C+GPA TS SYLNM+ I+DA+K TGA+AVHPGYGFLSEN  FA++L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++PETR+AMGEQAV +AKAV Y SAGTVEFLVD K+NF+FLEMNTRLQVEHPI+E ITG+D+V +M RV KG+ L  KQ+DIS+NGWA+ECRVYAEDPYKSFGLPS+GRL+ Y+EP  LP VR DSGIQEGS+ISI+YDPMI KLVT+G DR++AL  M  ALD+YVIRGVTHNIPLL +I+T P FV G+ITT +LPEVYPDGFKG
Sbjct:   42 QVIKTCRKMGIKTVAVHSDVDSASVHVKMADEAVCVGPAPTSKSYLNMDAIMDAIKHTGAQAVHPGYGFLSENKEFARRLAAESVTFIGPDTHAIQAMGDKIESKLLAKNAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETREGFRFSAQEAASSFGDDRLLIEKFIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPETRRAMGEQAVALAKAVKYSSAGTVEFLVDSKKNFFFLEMNTRLQVEHPITECITGLDLVQEMIRVAKGYSLKHKQADISINGWAIECRVYAEDPYKSFGLPSIGRLSQYQEPHLLPGVRVDSGIQEGSDISIFYDPMISKLVTHGRDRTEALKRMEDALDNYVIRGVTHNIPLLHEIITHPLFVKGDITTKFLPEVYPDGFKG 479          

Query: 1825 IANNFHLADKIITQNI-----DNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAG 2166
            + +N  L  +IIT  +        + + ++    + G   F Y   K     E      LSK+M  K   DTSS++ +PMPG V TVSVK G  VS+GQE+CV+EAMKMQNSM AAK  
Sbjct:  443 VTHNIPLLHEIITHPLFVKGDITTKFLPEVYPDGFKGLSFFIYFSIKRNHAAE------LSKYMPEKVEEDTSSILRSPMPGTVVTVSVKPGDMVSEGQEICVIEAMKMQNSMTAAKTA 555          

Query:  229 RIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKG 1542
            ++I +C++ GIK VAVHSDVD+ S  V+MADEA+C+GPA TS SYLNM+ I+DA+K TGA+AVHPGYGFLSEN  FA++L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG +  ++     +  +GYPVMIKASAGGGGKGMRIAW+D+E  EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++PETR+AMGEQAV +AKAV Y SAGTVEFLVD K+NF+FLEMNTRLQVEHPI+E ITG+D+V +M RV KG+ L  KQ+DIS+NGWA+ECRVYAEDPYKSFGLPS+GRL+ Y+EP  LP VR DSGIQEGS+ISI+YDPMI KLVT+G DR++AL  M  ALD+YVIRGVTHNIPLL +I+T P FV G+ITT +LPEVYPDGFKG
Sbjct:   42 QVIKTCRKMGIKTVAVHSDVDSASVHVKMADEAVCVGPAPTSKSYLNMDAIMDAIKHTGAQAVHPGYGFLSENKEFARRLAAESVTFIGPDTHAIQAMGDKIESKLLAKNAKVNTIPGFDGVVK-SELLSNCSLLLGYPVMIKASAGGGGKGMRIAWDDEETREGFRFSAQEAASSFGDDRLLIEKFIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPETRRAMGEQAVALAKAVKYSSAGTVEFLVDSKKNFFFLEMNTRLQVEHPITECITGLDLVQEMIRVAKGYSLKHKQADISINGWAIECRVYAEDPYKSFGLPSIGRLSQYQEPHLLPGVRVDSGIQEGSDISIFYDPMISKLVTHGRDRTEALKRMEDALDNYVIRGVTHNIPLLHEIITHPLFVKGDITTKFLPEVYPDGFKG 478          

Query: 1951 YKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVS 2208
            YKL+V +    +LSK+M  K   DTSS++ +PMPG V TVSVK G  VS+GQE+CV+EAMKMQNSM AAK   +    + PG + +
Sbjct:  539 YKLQVLTSHAAELSKYMPEKVEEDTSSILRSPMPGTVVTVSVKPGDMVSEGQEICVIEAMKMQNSMTAAKTAKL----YHPGGSAA 620          

Query:  163 KHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +++PKE  F KILIANRGEIACR+I +CK+ GIK VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+T A+AVHPGYGFLSEN  FAK+L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++PETR+AMGEQAV +AKAV Y SAGTVEFLVD ++NFYFLEMNTRLQVEHP++E ITG+D+V +M  V KG+PL  KQ DI ++GWAVECRVYAEDPYKSFGLPS+GRL+ Y+EP+HLP VR DSGIQ GS+ISIYYDPMI KLVTYG DR++AL  M  ALD+YVIRGVTHNIPLLR+++   RFV G+I+T +L +VYPDGFKG  LT  E   L A+++ VFV +++R + F +  R  +I       R D++   +W LS+   L  +D T    V    +   FTV  + G+   + + ++LA  +++ N+D  +  +Q +SR   G ++ Q++GT YK+ + + +  +L+KFML K   DTSS + +PMPG+V  VSVK G  V++GQE+CV+EAMKMQNSM A K G +K VH + G TV +GD+++ELE
Sbjct:   51 EYEPKEKTFDKILIANRGEIACRVIKTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFAKRLAAEDVTFIGPDTHAIQAMGDKIESKLLAKRAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDPETRQAMGEQAVALAKAVKYSSAGTVEFLVDSQKNFYFLEMNTRLQVEHPVTECITGLDLVQEMILVAKGYPLRHKQEDIPISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDSGIQPGSDISIYYDPMISKLVTYGSDRAEALKRMEDALDNYVIRGVTHNIPLLREVIINTRFVKGDISTKFLSDVYPDGFKGHTLTLSERNQLLAIASSVFVASQLRAQRFQEHSRVPVI-------RPDVA---KWELSVK--LHDEDHT----VVASNNGPAFTVEVD-GSKLNVTSTWNLASPLLSVNVDGTQRTVQCLSREAGGNMSIQFLGTVYKVHILTKLAAELNKFMLEKVPKDTSSTLCSPMPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKLVHCKAGDTVGEGDLLVELE 724          

Query:  193 KILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIK-IANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLAD--KIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            K+LIANRGEIACR+I + K+ G+++VAV+S+ D  S  V MADEA  IGPA +  SYL MEKI+   K + A+A+HPGYGFLSEN  FA+  +   ++F+GP S AI  MG K  SK I  AA V  + GY G+ + +D+ ++  A +IGYPVMIKA  GGGGKGMRI  +++E  E  + +R EAK SF DD MLIEK+++ PRH+E+Q+  D HGNA+YL ER+CS+QRR+QK+IEEAP+  INPE R+ +GE AV+ AKAV Y  AGTVEF++D + NFYF+EMNTRLQVEHP++E+ITG D+V    R+  G  + L Q +I + G A E R+YAEDP  +F +P  G L     P    + R ++G+++G E+S++YDPMI KLV +  DR  AL+ +   L  Y I G+  N+  L  +   P F +GN+ T+++P+ + D         KE+ + +A   ++  + E+ +         L   ++   F    S     ++S +  +  +    ++ ++V ++R           SFR+  +    D    +  +I+        ++R  S +I        + ++    +G  + K++ P          IAPM G ++ V VK G RV  G  L V+ AMKM++++ A K G IK V F  G   +    ++E E
Sbjct:   47 KVLIANRGEIACRVIRTAKKMGVQSVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLAMEKIIQVAKSSAAQAIHPGYGFLSENMEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKSIMAAAGVPVVEGYHGK-DQSDQCLREHAGKIGYPVMIKAVRGGGGKGMRIVRSEREFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGINPEVRRKLGEAAVRAAKAVKYVGAGTVEFIMDSRHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEIPLQGHAFEARIYAEDPDNNF-MPGAGPLVHLSTPSADMSTRIETGVRQGDEVSVHYDPMIAKLVVWASDRQSALSKLRYCLHQYNIVGLRSNVDFLLRLSGHPEFEAGNVHTDFIPQHHKDLLPSHSTIAKES-VCQAALGLILKEKEMTSAF------KLHTQDQFSPF--SFSSGRRLNISYTRNMTLRSGKSDIVIAVTYNRDGSYDMQIDNKSFRVLGDLSSEDGCTYLKSSING-------VARK-SKFILLDNTVHLFSMEGSIEVGIPVPKYLSPVSAEGAQGGTIAPMTGTIEKVFVKAGDRVKAGDSLMVMIAMKMEHTIKAPKDGRIKKVFFSEGAQANRHAPLVEFE 711          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIG----PAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKE 1563
            KK+++ANRGEIA R+  +C   GI+ VAV+S+ D      Q ADEA  IG    P Q   +YL++  I+   K+ G +AVHPGYGFLSE   FA+  +D  V F+GP+ + +  MGDK+E++ IA AA V  +PG D  I+   EA + +N  G+P++ KA+ GGGG+GMR+  + +E  E Y  + +EA ++FG+  + +EK+I KPRHIE+QI+ D++GN L+L ER+CSIQRR+QKV+E AP+T ++P+ R  +   +V++AK VGY++AGTVEFLVD     YF+E+N+RLQVEH ++E IT VD+VH    V +G  L    L+Q +I +NG A++CRV  EDP +SF  P  GR+  ++    +  +R D+    +G+ IS +YD ++ K++ +G+D   A   M +AL  + +RGV  NIP L++++   +F++G + T ++ E  P+ F   QL P +
Sbjct:   38 KKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQ---AYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDSPISSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQ-PDTGRIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGTVDTQFIDE-NPELF---QLRPAQ 494          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            PK + D    I APMPG V  + V  G +V+ GQ LCVL AMKM+  + +   G I+ VH     T+   D+I+E+E
Sbjct: 1102 PKALKDVKGQIGAPMPGKVIDIKVAAGDKVAKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE 1178          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIG----PAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKE 1563
            KK+++ANRGEIA R+  +C   GI+ VAV+S+ D      Q ADEA  IG    P Q   +YL++  I+   K+ G +AVHPGYGFLSE   FA+  +D  V F+GP+ + +  MGDK+E++ IA AA V  +PG D  I+   EA + +N  G+P++ KA+ GGGG+GMR+  + +E  E Y  + +EA ++FG+  + +EK+I KPRHIE+QI+ D++GN L+L ER+CSIQRR+QKV+E AP+T ++P+ R  +   +V++AK VGY++AGTVEFLVD     YF+E+N+RLQVEH ++E IT VD+VH    V +G  L    L+Q +I +NG A++CRV  EDP +SF  P  GR+  ++    +  +R D+    +G+ IS +YD ++ K++ +G+D   A   M +AL  + +RGV  NIP L++++   +F++G + T ++ E  P+ F   QL P +
Sbjct:   38 KKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQ---AYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDSPISSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQ-PDTGRIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGTVDTQFIDE-NPELF---QLRPAQ 494          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            PK + D    I APMPG V  + V  G +V+ GQ LCVL AMKM+  + +   G I+ VH     T+   D+I+E+E
Sbjct: 1102 PKALKDVKGQIGAPMPGKVIDIKVAAGDKVAKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE 1178          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIG----PAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKE 1563
            KK+++ANRGEIA R+  +C   GI+ VAV+S+ D      Q ADEA  IG    P Q   +YL++  I+   K+ G +AVHPGYGFLSE   FA+  +D  V F+GP+ + +  MGDK+E++ IA AA V  +PG D  I+   EA + +N  G+P++ KA+ GGGG+GMR+  + +E  E Y  + +EA ++FG+  + +EK+I KPRHIE+QI+ D++GN L+L ER+CSIQRR+QKV+E AP+T ++P+ R  +   +V++AK VGY++AGTVEFLVD     YF+E+N+RLQVEH ++E IT VD+VH    V +G  L    L+Q +I +NG A++CRV  EDP +SF  P  GR+  ++    +  +R D+    +G+ IS +YD ++ K++ +G+D   A   M +AL  + +RGV  NIP L++++   +F++G + T ++ E  P+ F   QL P +
Sbjct:   39 KKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQ---AYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDSPISSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQ-PDTGRIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGTVDTQFIDE-NPELF---QLRPAQ 495          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            PK + D    I APMPG V  + V  G +V+ GQ LCVL AMKM+  + +   G I+ VH     T+   D+I+E+E
Sbjct: 1103 PKALKDVKGQIGAPMPGKVIDIKVAAGDKVAKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE 1179          

Query:  163 KHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +++PKE  F KILIANRGEIACR+I +CK+ GIK VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+T A+AVHPGYGFLSEN  FAK+L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++PETR+AMGEQAV +AKAV Y SAGTVEFLVD ++NFYFLEMNTRLQVEHP++E ITG+D+V +M  V KG+PL  KQ DI ++GWAVECRVYAEDPYKSFGLPS+GRL+ Y+EP+HLP VR DSGIQ GS+ISIYYDPMI KLVTYG DR++AL  M  ALD+YVIRGVTHNIPLLR+++   RFV G+I+T +L +VYPDGFKG  LT  E   L A+++ VFV +++R + F +  R  +I       R D++   +W LS+   L  +D T    V    +   FTV  + G+   + + ++LA  +++ N+D  +  +Q +SR   G ++ Q++GT YK+ + + +  +L+KFML K   DTSS + +PMPG+V  VSVK G  V++GQE+CV+EAMKMQNSM A K G +K VH + G TV +GD+++ELE
Sbjct:   51 EYEPKEKTFDKILIANRGEIACRVIKTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFAKRLAAEDVTFIGPDTHAIQAMGDKIESKLLAKRAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDPETRQAMGEQAVALAKAVKYSSAGTVEFLVDSQKNFYFLEMNTRLQVEHPVTECITGLDLVQEMILVAKGYPLRHKQEDIPISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDSGIQPGSDISIYYDPMISKLVTYGSDRAEALKRMEDALDNYVIRGVTHNIPLLREVIINTRFVKGDISTKFLSDVYPDGFKGHTLTLSERNQLLAIASSVFVASQLRAQRFQEHSRVPVI-------RPDVA---KWELSVK--LHDEDHT----VVASNNGPAFTVEVD-GSKLNVTSTWNLASPLLSVNVDGTQRTVQCLSREAGGNMSIQFLGTVYKVHILTKLAAELNKFMLEKVPKDTSSTLCSPMPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKLVHCKAGDTVGEGDLLVELE 724          

Query:  166 HDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +DP E  F KIL+ANRGEIACR+I +CK+ GIK VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+T A+AVHPGYGFLSEN  FA+ L   +VVF+GP++ AI +MGDKIESK +A  A+V+ IPG+DG + D +EA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++LS  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++ ETR+AMGEQAV +A+AV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHP++E ITG+D+V +M RV KG+PL  KQ+DI +NGWAVECRVYAEDPYKSFGLPS+GRL+ Y+EPLHLP VR DSGIQ GS+ISIYYDPMI KL+TYG DR++AL  M  ALD+YVIRGVTHNI LLR+++   RFV G+I+T +L +VYPDGFKG  LT  E   L A+++ +FV  ++R + F +  R  +I       + D+++   W LS+    +  DK   V  S   + S F+V  + G+   + + ++LA  +++ ++D  +  +Q +SR   G ++ Q++GT YK+ + + +  +L+KFML K   DTSSV+ +PMPG+V  VSVK G  V++GQE+CV+EAMKMQNSM A K G +K+VH Q G TV +GD+++ELE
Sbjct:   56 YDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPDGFKGHMLTKSEKNQLLAIASSLFVAFQLRAQHFQENSRMPVI-------KPDIAN---WELSV----KLHDKVHTVVAS--NNGSVFSVEVD-GSKLNVTSTWNLASPLLSVSVDGTQRTVQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE 728          

Query:  163 KHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +++PKE  F KILIANRGEIACR+I +C++ GI+ VA+HSDVDA S  V+MADEA+C+GPA TS SYLNM+ I++A+K+TGA+AVHPGYGFLSEN  FAK L   +V F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRI W+D+E  +G++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++PETR+AMGEQAV   KAV Y SAGTVEFLVD ++NFYFLEMNTRLQVEHP++E ITG+D+V +M  V KG+PL  KQ DI ++GWAVECRVYAEDPYKSFGLPS+GRL+ Y+EP+HLP VR DSGIQ GS+ISIY+DPMI KLVTYG DR++AL  M  ALDSYVIRGVTHNIPLLR+++   RFV G+I+T +L +VYPDGFKG  LTP E   L A+++ +FV +++R + F +  R  +I       R D++   +W LS+   L  +D T    V    +   F V  + G+   + + ++LA  +++ N+D  +  +Q +S +  G ++ Q++GT YK+ + + +  +L+KFML K   DTSSV+ +P PG+V  VSVK G  V++GQE+CV+EAMKMQNSM A K G +K VH + G TV +GD+++ELE
Sbjct:   64 EYEPKEKTFDKILIANRGEIACRVIKTCRKMGIRTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTGAQAVHPGYGFLSENKEFAKCLAAEDVTFIGPDTHAIQAMGDKIESKLLAKRAKVNTIPGFDGVLKDADEAVRIAREIGYPVMIKASAGGGGKGMRIPWDDEETRDGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDPETRRAMGEQAVAWPKAVKYSSAGTVEFLVDSQKNFYFLEMNTRLQVEHPVTECITGLDLVQEMILVAKGYPLRHKQEDIPISGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDSGIQPGSDISIYHDPMISKLVTYGSDRAEALKRMEDALDSYVIRGVTHNIPLLREVIINTRFVKGDISTKFLSDVYPDGFKGHMLTPSERDQLLAIASSLFVASQLRAQRFQEHSRVPVI-------RPDVA---KWELSVK--LHDEDHT----VVASNNGPTFNVEVD-GSKLNVTSTWNLASPLLSVNVDGTQRTVQCLSPDAGGNMSIQFLGTVYKVHILTKLAAELNKFMLEKVPKDTSSVLRSPKPGVVVAVSVKPGDMVAEGQEICVIEAMKMQNSMTAGKMGKVKLVHCKAGDTVGEGDLLVELE 737          

Query:  166 HDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPE--EWHLSIS-----HGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +D  E  F KILIANRGEIACR+I +CK+ GIK VAVHSDVDA S  V MADEA+C+GPA TS SYLNM+ I++AV+ T A+AVHPGYGFLSEN  FAK L    V+F+GP++ AI +MGDKIESK +A  AKV+ IPG+DG + D DEA++IA +IGYPVMIKASAGGGGKGMRIAW+D+E  +G++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPS F++ ETR+AMGEQAV +AKAV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHP++E ITG+D+V +M RV KG+PL  +Q+DI +NGWAVECRVYAEDPYKSFGLPS+GRL+ Y+EP+HLP VR DSGIQ GS+ISIYYDPMI KL+TYG +R +AL  M  ALD+YVIRGVTHNI LLR+++   RFV G+I T +L +VYPDGFKG +LT  E   L A+++ +FV +++R + F          ++ E+ R  +  P+   W LSI      H + + +      V VD            G+   + + ++LA  +++ +ID  +  +Q +SR+  G ++ Q++GT YK+ + + +  +L+KFML K   DTSS++ +PMPG+V  VSVK G  V++GQE+CV+EAMKMQNSM A K G +K+VH + G TV +GD+++ELE
Sbjct:   56 YDSNEKTFDKILIANRGEIACRVIKTCKKMGIKTVAVHSDVDASSVHVTMADEAVCVGPAPTSKSYLNMDAIMEAVRTTRAQAVHPGYGFLSENKEFAKCLAAEGVIFIGPDTHAIQAMGDKIESKLLAKKAKVNTIPGFDGVVKDADEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDSETRRAMGEQAVALAKAVNYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHRQADIPINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPIHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSNRMEALKRMENALDNYVIRGVTHNIALLREVIINSRFVEGDINTKFLSDVYPDGFKGHKLTEDERNQLLAIASSLFVASQLRAQRF----------QEPENSRVPIIKPQVANWELSIRLHDEVHTVTASNSGPTFSVEVD------------GSKLNVTSTWNLASPLLSVSIDGTQRTIQCLSRDAGGNMSIQFLGTVYKVHILTKLAAELNKFMLEKAAEDTSSILHSPMPGVVVAVSVKPGDLVAEGQEICVIEAMKMQNSMTAGKTGKVKSVHCKAGDTVGEGDLLVELE 730          

Query:  139 ARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFL--KKDRSLLIAEKSESFRGDLSHP-EEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
             + IY     D  E KF KILIANRGEIACR+I + +  GIK VAVHSDVD+ S  V+MADEA+C+G A T+ SYL  ++IL AV+ TGA+AVHPGYGFLSENT FA +LE     F+GPNSKAI  MGDKI SK+IA AA+V  IPGYDGEI D D  +K++  IGYPVMIKASAGGGGKGMR+AWNDK+A EGY+LS+ EA SSFGDDRML+EK+I+ PRHIE+Q++CDKHGNAL+LNERECSIQRRNQKVIEEAPS+F+ PE R+ MGEQAVQ+AKAVGYDSAGTVEFLVD +RNFYFLEMNTRLQVEHPI+E ITG+DIV QM RV  GHPL + Q  + +NGWA E RVYAEDPYK FGLPSVGRL+ Y EP H+  VRCDSGI+EGSEISIYYDP+ICKLVT+G++R +AL  M +ALD+YVIRGVTHNIPLLRDIV E RF +G+ITT YLPEVYP+GF+G  L+PKE  ++ A ++ +  +   R   FL   K RS  +A  S++++   S P +E      H +E +       V    +++   +    G +  I+ + +L+  + +  +D + I  Q++ +  +G IT  Y GT +K+KV      K  ++M  K  VD S+V+++PMPG +K V+VK G  VS+GQEL V+EAMKMQNS+ A K G +KAV+ + G TV +G++++ELE
Sbjct:   33 GKEIYTTVGIDYNEPKFDKILIANRGEIACRVIKTARAMGIKTVAVHSDVDSNSLHVKMADEAVCVGEAPTAKSYLRADRILQAVEDTGAQAVHPGYGFLSENTKFAAELEKAGAKFIGPNSKAILDMGDKIHSKKIATAARVSMIPGYDGEIADEDMCVKVSRDIGYPVMIKASAGGGGKGMRVAWNDKQAREGYRLSKQEAASSFGDDRMLVEKFIDNPRHIEMQVLCDKHGNALWLNERECSIQRRNQKVIEEAPSSFVPPEMRRKMGEQAVQLAKAVGYDSAGTVEFLVDSQRNFYFLEMNTRLQVEHPITECITGIDIVQQMLRVSYGHPLPITQEQVPLNGWAFESRVYAEDPYKGFGLPSVGRLSRYVEPKHVDGVRCDSGIREGSEISIYYDPLICKLVTHGDNREQALNRMQEALDNYVIRGVTHNIPLLRDIVQEKRFRTGDITTKYLPEVYPEGFQGTSLSPKEQDVVIAFASALNARKLARANQFLNQNKQRSTHVASFSKTYKFVSSLPVKEGERPTEHAVEVE------FVEGSANKAQVRIG---GKTVTISGDLNLSHPVNSIEVDGEHITTQIVGKR-AGEITVLYKGTPFKVKVLPEQAVKYLQYMKEKAKVDLSTVVLSPMPGAIKNVNVKPGDMVSEGQELVVMEAMKMQNSLHAGKTGRVKAVNVKVGATVDEGEVLVELE 724          

Query:  133 SAARN---IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIA-EKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            SAAR    IYWNDKHD  E++F+KILIANRGEIACR+INSCKR GIK+VAVHS++DA S+FVQ+ADEA+CIGPA TS SYLNME IL AVKQTGA+AVHPGYGFLSENTVFAK+LED++VVFLGPNSKAI +MGDKIESKRIAN AKV+CIPG+DGE+ D DEA+KIAN IGYPVMIKASAGGGGKGMRIAWNDK+A EGY+LS+ EAKSSFGDDRMLIEK+I+KPRHIE+Q++CD+HGNALYLNERECSIQRRNQKVIEEAPS +I+P+TRKAMG QA  +AKAVGYDSAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITGVDIVHQM RVGKGHPLLL Q DI V GWAVECRVYAEDPYK+FGLPS+GRLT+Y EP  L NVRCDSGIQEGSEISIYYDPMICKLVTYG+DR  AL TMV ALD+YVIRGVTHNIPLLRDIVTE RFVSG+ITTNYLPEVYPDGF+GKQ + ++   + A+SAVVF KN++RNKT+LKKDRS ++A E  +SF        +W +  S  L+ +D    +   V +    FTV FE   + +I +NF LA+K+I   I+ D + +Q+MSR++   +T QYMGTK    V +   + LSKFM  +   DTS+ I APMPGLVK+V V VGQ V++GQE+CVLEAMKMQNS+  A AG +KAVHF+ G+TV++ D+I+ELE
Sbjct: 1448 SAARQADAIYWNDKHDSNESRFEKILIANRGEIACRVINSCKRLGIKSVAVHSEIDASSKFVQLADEAVCIGPAPTSKSYLNMEAILQAVKQTGAQAVHPGYGFLSENTVFAKRLEDLDVVFLGPNSKAIRAMGDKIESKRIANKAKVNCIPGFDGEVKDADEAVKIANDIGYPVMIKASAGGGGKGMRIAWNDKQAREGYRLSQEEAKSSFGDDRMLIEKFIDKPRHIEVQVLCDRHGNALYLNERECSIQRRNQKVIEEAPSVYIDPDTRKAMGAQATALAKAVGYDSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGVDIVHQMIRVGKGHPLLLTQKDIGVKGWAVECRVYAEDPYKAFGLPSIGRLTTYSEPTALENVRCDSGIQEGSEISIYYDPMICKLVTYGKDRQSALNTMVNALDNYVIRGVTHNIPLLRDIVTENRFVSGDITTNYLPEVYPDGFRGKQFSDRDRLNIAAVSAVVFAKNDLRNKTYLKKDRSNIVAGEAKKSF--------DWDIVAS--LDGKD----LLCRVSYKEGGFTVAFEGSETLQIKDNFSLANKVIPAVINGDSVCMQMMSRSFDERVTLQYMGTKCTTIVRTARAYDLSKFMPVRSDKDTSTTIKAPMPGLVKSVGVTVGQTVAEGQEICVLEAMKMQNSLSCAIAGKVKAVHFKAGETVNEEDVIVELE 2138          

Query:  133 SAARN---IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHS-----------DVDALSRFVQM 315
            SAAR    IYWNDKHD  E++F+KILIANRGEIACR+INSCKR GIK+VAV +           DV   S+  Q+
Sbjct:  900 SAARQADAIYWNDKHDSNESRFEKILIANRGEIACRVINSCKRLGIKSVAVFTLKRMTDFLNQFDVSCRSKIAQL 974          

Query:  133 SAARN---IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIA-EKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            SAAR    IYWNDKHD  E++F+KILIANRGEIACR+INSCKR GIK+VAVHS++DA S+FVQ+ADEA+CIGPA TS SYLNME IL AVKQTGA+AVHPGYGFLSENTVFAK+LED++VVFLGPNSKAI +MGDKIESKRIAN AKV+CIPG+DGE+ D DEA+KIAN+IGYPVMIKASAGGGGKGMRIAWNDK+A EGY+LS+ EAKSSFGDDRMLIEK+I+KPRHIE+Q++CD+HGNALYLNERECSIQRRNQKVIEEAPS +I+P+TRKAMG QA  +AKAVGYDSAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITGVDIVHQM RVGKGHPLLL Q DI V GWAVECRVYAEDPYK+FGLPS+GRLT+Y EP  L NVRCDSGIQEGSEISIYYDPMICKLVTYG+DR  AL TMV ALD+YVIRGVTHNIPLLRDIVTE RFVSGNITTNYLPEVYPDGF+GKQ + ++   + A+SAVVF KN++RNKT+LKKDRS ++A E  +SF        +W +  S  L+ +D    +   V +    FTV FE   + +I +NF LA+K+I   I+ D + +Q+MSR++   +T QYMGTK    V +   + LSKFM  +   DTS+ I APMPGLVK++ V VGQ V++GQE+CVLEAMKMQNS+  A AG +KAVHF+ G+TV++ D+I+ELE
Sbjct:   26 SAARQADAIYWNDKHDSNESRFEKILIANRGEIACRVINSCKRLGIKSVAVHSEIDASSKFVQLADEAVCIGPAPTSKSYLNMEAILQAVKQTGAQAVHPGYGFLSENTVFAKRLEDLDVVFLGPNSKAIRAMGDKIESKRIANKAKVNCIPGFDGEVKDADEAVKIANEIGYPVMIKASAGGGGKGMRIAWNDKQAREGYRLSQEEAKSSFGDDRMLIEKFIDKPRHIEVQVLCDRHGNALYLNERECSIQRRNQKVIEEAPSVYIDPDTRKAMGAQATALAKAVGYDSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGVDIVHQMIRVGKGHPLLLTQKDIGVKGWAVECRVYAEDPYKAFGLPSIGRLTTYSEPTALENVRCDSGIQEGSEISIYYDPMICKLVTYGKDRQSALNTMVNALDNYVIRGVTHNIPLLRDIVTENRFVSGNITTNYLPEVYPDGFRGKQFSDRDRLNIAAVSAVVFAKNDLRNKTYLKKDRSNIVAGEAKKSF--------DWDIVAS--LDGKD----LLCRVSYKEGGFTVAFEGSETLQIKDNFSLANKVIPAVINGDSVCMQMMSRSFDERVTLQYMGTKCTTIVRTARAYDLSKFMPVRSDKDTSTTIKAPMPGLVKSIGVTVGQTVAEGQEICVLEAMKMQNSLSCAIAGKVKAVHFKAGETVNEEDVIVELE 716          

Query:  133 SAARN---IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIA-EKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            SAAR    IYWNDKHD  E++F+KILIANRGEIACR+INSCKR GIK+VAVHS++DA S+FVQ+ADEA+CIGPA TS SYLNME IL AVKQTGA+AVHPGYGFLSENTVFAK+LED++VVFLGPNSKAI +MGDKIESKRIAN AKV+CIPG+DGE+ D DEA+KIAN IGYPVMIKASAGGGGKGMRIAWNDK+A EGY+LS+ EAKSSFGDDRMLIEK+I+KPRHIE+Q++CD+HGNALYLNERECSIQRRNQKVIEEAPS +I+P+TRKAMG QA  +AKAVGYDSAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITGVDIVHQM RVGKGHPLLL Q DI V GWAVECRVYAEDPYK+FGLPS+GRLT+Y EP  L NVRCDSGIQEGSEISIYYDPMICKLVTYG+DR  AL TMV ALD+YVIRGVTHNIPLLRDIVTE RFVSG+ITTNYLPEVYPDGF+GKQ + ++   + A+SAVVF KN++RNKT+LKKDRS ++A E  +SF        +W +  S  L+ +D    +   V +    FTV FE   + +I +NF LA+K+I   I+ D + +Q+MSR++   +T QYMGTK    V +   + LSKFM  +   DTS+ I APMPGLVK+V V VGQ V++GQE+CVLEAMKMQNS+  A AG +KAVHF+ G+TV++ D+I+ELE
Sbjct:   26 SAARQADAIYWNDKHDSNESRFEKILIANRGEIACRVINSCKRLGIKSVAVHSEIDASSKFVQLADEAVCIGPAPTSKSYLNMEAILQAVKQTGAQAVHPGYGFLSENTVFAKRLEDLDVVFLGPNSKAIRAMGDKIESKRIANKAKVNCIPGFDGEVKDADEAVKIANDIGYPVMIKASAGGGGKGMRIAWNDKQAREGYRLSQEEAKSSFGDDRMLIEKFIDKPRHIEVQVLCDRHGNALYLNERECSIQRRNQKVIEEAPSVYIDPDTRKAMGAQATALAKAVGYDSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGVDIVHQMIRVGKGHPLLLTQKDIGVKGWAVECRVYAEDPYKAFGLPSIGRLTTYSEPTALENVRCDSGIQEGSEISIYYDPMICKLVTYGKDRQSALNTMVNALDNYVIRGVTHNIPLLRDIVTENRFVSGDITTNYLPEVYPDGFRGKQFSDRDRLNIAAVSAVVFAKNDLRNKTYLKKDRSNIVAGEAKKSF--------DWDIVAS--LDGKD----LLCRVSYKEGGFTVAFEGSETLQIKDNFSLANKVIPAVINGDSVCMQMMSRSFDERVTLQYMGTKCTTIVRTARAYDLSKFMPVRSDKDTSTTIKAPMPGLVKSVGVTVGQTVAEGQEICVLEAMKMQNSLSCAIAGKVKAVHFKAGETVNEEDVIVELE 716          

Query:  133 SAARN---IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIA-EKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            SAAR    IYWNDKHD  E++F+KILIANRGEIACR+INSCKR GIK+VAVHS++DA S+FVQ+ADEA+CIGPA TS SYLNME IL AVKQTGA+AVHPGYGFLSENTVFAK+LED++VVFLGPNSKAI +MGDKIESKRIAN AKV+CIPG+DGE+ D DEA+KIAN IGYPVMIKASAGGGGKGMRIAWNDK+A EGY+LS+ EAKSSFGDDRMLIEK+I+KPRHIE+Q++CD+HGNALYLNERECSIQRRNQKVIEEAPS +I+P+TRKAMG QA  +AKAVGYDSAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITGVDIVHQM RVGKGHPLLL Q DI V GWAVECRVYAEDPYK+FGLPS+GRLT+Y EP  L NVRCDSGIQEGSEISIYYDPMICKLVTYG+DR  AL TMV ALD+YVIRGVTHNIPLLRDIVTE RFVSG+ITTNYLPEVYPDGF+GKQ + ++   + A+SAVVF KN++RNKT+LKKDRS ++A E  +SF        +W +  S  L+ +D    +   V +    FTV FE   + +I +NF L+DK+I   I+ + + +Q+M+R++   +T QY+GTK    V +   + LSKFM  +   DTS+ I APMPGLVK+V V VGQ V++GQE+CVLEAMKMQNS+  A AG +KAVHF+ G+TV++ D+I+ELE
Sbjct:   23 SAARQAEAIYWNDKHDSNESRFEKILIANRGEIACRVINSCKRLGIKSVAVHSEIDASSKFVQLADEAVCIGPAPTSKSYLNMEAILQAVKQTGAQAVHPGYGFLSENTVFAKRLEDLDVVFLGPNSKAIRAMGDKIESKRIANKAKVNCIPGFDGEVKDADEAVKIANDIGYPVMIKASAGGGGKGMRIAWNDKQAREGYRLSQEEAKSSFGDDRMLIEKFIDKPRHIEVQVLCDRHGNALYLNERECSIQRRNQKVIEEAPSVYIDPDTRKAMGAQATALAKAVGYDSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGVDIVHQMIRVGKGHPLLLTQKDIGVKGWAVECRVYAEDPYKAFGLPSIGRLTTYSEPTALENVRCDSGIQEGSEISIYYDPMICKLVTYGKDRQSALNTMVNALDNYVIRGVTHNIPLLRDIVTENRFVSGDITTNYLPEVYPDGFRGKQFSDRDRLNIAAVSAVVFAKNDLRNKTYLKKDRSNIVAGEAKKSF--------DWDIVAS--LDGKD----LLCRVSYKEGGFTVAFEGSETLQIKDNFSLSDKVIPAVINGESVCMQMMARSFDERVTLQYLGTKCTTIVRTARAYDLSKFMPVRSDKDTSTTIKAPMPGLVKSVGVTVGQTVAEGQEICVLEAMKMQNSLSCAIAGKVKAVHFKAGETVNEEDVIVELE 713          

Query:  133 SAARN---IYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIA-EKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            SAAR    IYWNDKHD  E++F+KILIANRGEIACR+INSCKR GIK+VAVHS++DA S+FVQ+ADEA+CIGPA TS SYLNME IL AVKQTGA+AVHPGYGFLSENTVFAK+LED++VVFLGPNSKAI +MGDKIESKRIAN AKV+CIPG+DGE+ D DEA+KIAN IGYPVMIKASAGGGGKGMRIAWNDK+A EGY+LS+ EAKSSFGDDRMLIEK+I+KPRHIE+Q++CD+HGNALYLNERECSIQRRNQKVIEEAPS +I+P+TRKAMG QA  +AKAVGYDSAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITGVDIVHQM RVGKGHPLLL Q DI V GWAVECRVYAEDPYK+FGLPS+GRLT+Y EP  L NVRCDSGIQEGSEISIYYDPMICKLVTYG+DR  AL TMV ALD+YVIRGVTHNIPLLRDIVTE RFVSG+ITTNYLPEVYPDGF+GKQ + ++   + A+SAVVF KN++RNKT+LKKDRS ++A E  +SF        +W +  S  L+ +D    +   V +    FTV FE   + +I +NF L+DK+I   I+ + + +Q+M+R++   +T QY+GTK    V +   + LSKFM  +   DTS+ I APMPGLVK+V V VGQ V++GQE+CVLEAMKMQNS+  A AG +KAVHF+ G+TV++ D+I+ELE
Sbjct:   27 SAARQAEAIYWNDKHDSNESRFEKILIANRGEIACRVINSCKRLGIKSVAVHSEIDASSKFVQLADEAVCIGPAPTSKSYLNMEAILQAVKQTGAQAVHPGYGFLSENTVFAKRLEDLDVVFLGPNSKAIRAMGDKIESKRIANKAKVNCIPGFDGEVKDADEAVKIANDIGYPVMIKASAGGGGKGMRIAWNDKQAREGYRLSQEEAKSSFGDDRMLIEKFIDKPRHIEVQVLCDRHGNALYLNERECSIQRRNQKVIEEAPSVYIDPDTRKAMGAQATALAKAVGYDSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGVDIVHQMIRVGKGHPLLLTQKDIGVKGWAVECRVYAEDPYKAFGLPSIGRLTTYSEPTALENVRCDSGIQEGSEISIYYDPMICKLVTYGKDRQSALNTMVNALDNYVIRGVTHNIPLLRDIVTENRFVSGDITTNYLPEVYPDGFRGKQFSDRDRLNIAAVSAVVFAKNDLRNKTYLKKDRSNIVAGEAKKSF--------DWDIVAS--LDGKD----LLCRVSYKEGGFTVAFEGSETLQIKDNFSLSDKVIPAVINGESVCMQMMARSFDERVTLQYLGTKCTTIVRTARAYDLSKFMPVRSDKDTSTTIKAPMPGLVKSVGVTVGQTVAEGQEICVLEAMKMQNSLSCAIAGKVKAVHFKAGETVNEEDVIVELE 717          

Query:  154 WNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVH-VSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            ++  +DP E  F KILIANRGEIACR+I +CK+ GIK VAVHSDVD+ +  V+MADEA C+GPA TS SYLNM+ I++A++QTGA+AVHPGYGFLSEN  FA++L    V F+GP++ AI +MGDKIESK IA AAKV+ IPG+DG + + +EA+KIA +IGYPVMIKASAGGGGKGMRIAWND+E  EG++ S  EA SSFGDDR+LIEKYI+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++P TR+AMGEQAV +AKAV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITG+D+V QM RV KG+ L  KQ DI +NGWA+E RVYAEDPYKSFGLPS+GRL+ Y+EPL+LP VR DSGIQEGS+ISIYYDPMI KLVTYG  R++AL  M  ALD+YVIRGVTHNIPLLR+I+  PRF+SG+I+TN+LPEVYP+GFKG  L   E   L A +A + V  ++R++ FL + R   + ++  +          W L +       +  + VH + V    + +TV  + G    ++  ++LA  ++   I+                IT QY+GT +K++V S +   L+K M  K   DTSS++ +PMPG V  VSVK G  V++GQE+CV+EAMKMQNSM AAK   +K+VH   G+TV +GD+++ELE
Sbjct:   35 YSTVYDPHEKTFDKILIANRGEIACRVIKTCKKMGIKTVAVHSDVDSSAVHVKMADEAFCVGPAPTSKSYLNMDAIMEAIRQTGAQAVHPGYGFLSENKEFARRLAADGVSFIGPDTHAIQAMGDKIESKLIAKAAKVNTIPGFDGVVKNAEEAVKIAGEIGYPVMIKASAGGGGKGMRIAWNDEETREGFRFSSQEAASSFGDDRLLIEKYIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPVTRRAMGEQAVSLAKAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGLDLVQQMIRVAKGYKLQHKQEDIPINGWAIESRVYAEDPYKSFGLPSIGRLSQYEEPLNLPGVRVDSGIQEGSDISIYYDPMISKLVTYGSTRAEALKKMEDALDNYVIRGVTHNIPLLREIIVHPRFISGDISTNFLPEVYPEGFKGHPLAAGEQRELLAAAAALHVAAQLRSQRFLGQQRVSSVPQERRN----------WELCV-------ELDKRVHMLGVSRSGNSYTVEID-GEKVVVSGEWNLASALLPLTINE---------------ITLQYLGTSFKVRVLSKLAASLNKLMPEKIPEDTSSILRSPMPGTVVAVSVKPGDTVAEGQEICVIEAMKMQNSMTAAKTAKVKSVHCTAGETVGEGDLLVELE 696          

Query:  202 IANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVH-VSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVV-DTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            IANRGEIACR+I +CK+ GIK VAVHSDVD+ +  V+MADEA C+GPA TS SYLNM+ I++A++QTGA+AVHPGYGFLSEN  FA++L    V F+GP++ AI +MGDKIESK IA AAKV+ IPG+DG + + +EA+KIA +IGYPVMIKASAGGGGKGMRIAWND+E  EG++ S  EA SSFGDDR+LIEKYI+ PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++P TR+AMGEQAV +AKAV Y SAGTVEFLVD K+NFYFLEMNTRLQVEHPI+E ITG+D+V QM RV KG+ L  KQ DI +NGWA+E RVYAEDPYKSFGLPS+GRL+ Y+EPL+LP VR DSGIQEGS+ISIYYDPMI KLVTYG  R++AL  M  ALD+YVIRGVTHNIPLLR+I+  PRF+SG+I+TN+LPEVYP+GFKG  L   E   L A +A + V  ++R++ FL + R   + ++  +          W L +       +  + VH + V    + +TV  + G    ++  ++LA  ++   I+   I+L +  +  +  +  +   +  KL              +P+K+  DTSS++ +PMPG V  VSVK G  V++GQE+CV+EAMKMQNSM AAK   +K+VH   G+TV +GD+++ELE
Sbjct:    1 IANRGEIACRVIKTCKKMGIKTVAVHSDVDSSAVHVKMADEAFCVGPAPTSKSYLNMDAIMEAIRQTGAQAVHPGYGFLSENKEFARRLAADGVSFIGPDTHAIQAMGDKIESKLIAKAAKVNTIPGFDGVVKNAEEAVKIAGEIGYPVMIKASAGGGGKGMRIAWNDEETREGFRFSSQEAASSFGDDRLLIEKYIDNPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPVTRRAMGEQAVSLAKAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPITECITGLDLVQQMIRVAKGYKLQHKQEDIPINGWAIESRVYAEDPYKSFGLPSIGRLSQYEEPLNLPGVRVDSGIQEGSDISIYYDPMISKLVTYGSTRAEALKKMEDALDNYVIRGVTHNIPLLREIIVHPRFISGDISTNFLPEVYPEGFKGHPLAAGEQRELLAAAAALHVAAQLRSQRFLGQQRVSSVPQERRN----------WELCV-------ELDKRVHMLGVSRSGNSYTVEID-GEKVVVSGEWNLASALLPLTINGVPILLSIQCKTQNLLLLSKLAASLNKL--------------MPEKIPEDTSSILRSPMPGTVVAVSVKPGDTVAEGQEICVIEAMKMQNSMTAAKTAKVKSVHCTAGETVGEGDLLVELE 648          

Query:  181 TKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPE 1518
             + +K+LIANRGEIACR++ + K+ G+++VAV+SD D  S  V MADEA  IG AQ+  SYL MEK+L+  K++ A+AVHPGYGFLSENT FA+  +   ++F+GP S AI  MG K  SK I +AA V  I GY GE     +    A +IGYPVMIKA  GGGGKGMRIA ++ E  E  + +R EA+ SF DD ML+EK++  PRH+E+Q+  D+HGNA+YL ER+CS+QRR+QK+IEEAP   I+PE R+ +GE AV+ AKAV Y  AGTVEF++D + NFYF+EMNTRLQVEHP+SE+ITG D+V    RV  G  + L Q DI + G + E R+YAEDP   F +P  G L     P    + R ++G+++G E+S +YDPMI KLV +GEDR  AL  +   L  Y I G+  NI  L ++   P F +GN+ T+++P+
Sbjct:   33 ARIEKVLIANRGEIACRVMRTAKKMGVRSVAVYSDADRHSMHVAMADEAYHIGAAQSQQSYLCMEKVLEVAKKSSAQAVHPGYGFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKHIMSAAGVPIIEGYHGEDQSDKKLQAEAARIGYPVMIKAVRGGGGKGMRIAHSEAEFHEQLESARREARKSFNDDVMLVEKFVENPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGISPEVRRKLGEAAVRAAKAVNYVGAGTVEFIMDSQHNFYFMEMNTRLQVEHPVSEMITGTDLVEWQLRVAAGEKIPLSQEDIVLRGHSFEARIYAEDPNNDF-MPGAGHLQHLSNPQADEHTRIETGVRDGDEVSAHYDPMIAKLVVWGEDRPAALKKLRYCLRQYNIVGLNTNIDFLLNLSGHPEFEAGNVHTSFIPQ 477          

Query: 1987 LSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVS 2208
            L KF+            +APM G ++ + VK G  V  G  L V+ AMKM++++ A KAGVIK V F+ G   S
Sbjct:  619 LPKFLAGVGTTGAQGGAVAPMSGTIEKIFVKAGDTVQKGDPLVVMIAMKMEHTIRAPKAGVIKKVLFREGSQAS 692          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPE 1518
            KK+++ANR    C  + +C   GI+ VAV+S+ D      Q ADEA  IG     ++ YL++  I+   K+   +A+HPGYGFLSE + FA+  ED  V F+GP+   +  MGDK+E++ +A  A V  +PG D  I    EA + A   G+P++ KA+ GGGG+GMR+    +E  E Y+ + +EA ++FG+  + +EK+I KPRHIE+QI+ DK+GN ++L ER+CSIQRR+QKV+E AP+  ++P  R  +   +V +AK VGY++AGTVEFLVD     YF+E+N+RLQVEH ++E IT VD+VH   RV +G  L    LKQ  I +NG A++CRV  EDP + F  P  GRL  ++    +  +R DS    +G+ IS +YD ++ K+++ G+D   A + M++AL  + IRGV  NIP L+++++  +F+   + T ++ E
Sbjct:   40 KKVMVANRDCNPC--VRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGKGLPPVAAYLHIPDIIKVAKENNVDAIHPGYGFLSERSDFAQACEDAGVRFVGPSPDVVRKMGDKVEARALAIQAGVPVVPGTDAPITSQQEAHEFAKTYGFPIIFKAAYGGGGRGMRVVREYEELEENYQRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDKYGNVIHLYERDCSIQRRHQKVVEIAPAAQLDPHLRDRLTSDSVTLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQLRVCEGRSLPELGLKQDKIRINGCAIQCRVTTEDPARGFQ-PDTGRLEVFRSAEGM-GIRLDSASAFQGAVISPHYDSLLVKVISSGKDLPTAASKMLRALAEFRIRGVKTNIPFLQNVLSNNQFLHSTVDTQFIDE 483          

Query: 1924 ITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIEL 2232
            + F+  G    + V+  +  K   F  PK + D    + APMPG V  V VK GQ+V  GQ LCVL AMKM+  + +  +G +  V+ +   ++   D+I+E+
Sbjct:  993 VFFELNGQLRSVLVKDTVAMKEMHFH-PKALKDVRGQVGAPMPGKVVEVKVKQGQKVEKGQPLCVLSAMKMETVVNSPLSGTVAKVYVKTDTSLEGDDLILEI 1094          

Query:  310 QMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPE 1518
            Q ADEA  IG     ++ YL++  I+   K+   +A+HPGYGFLSE + FA+  ED  V F+GP+   +  MGDK+E++ +A  A V  +PG D  I    EA + A   G+P++ KA+ GGGG+GMR+    +E  E Y+ + +EA ++FG+  + +EK+I KPRHIE+QI+ DK+GN ++L ER+CSIQRR+QKV+E AP+  ++P  R  +   +V +AK VGY++AGTVEFLVD     YF+E+N+RLQVEH ++E IT VD+VH   RV +G  L    LKQ  I +NG A++CRV  EDP + F  P  GRL  ++    +  +R DS    +G+ IS +YD ++ K+++ G+D   A + M++AL  + IRGV  NIP L+++++  +F+   + T ++ E
Sbjct:    4 QKADEAYLIGKGLPPVAAYLHIPDIIKVAKENNVDAIHPGYGFLSERSDFAQACEDAGVRFVGPSPDVVRKMGDKVEARALAIQAGVPVVPGTDAPITSQQEAHEFAKTYGFPIIFKAAYGGGGRGMRVVREYEELEENYQRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDKYGNVIHLYERDCSIQRRHQKVVEIAPAAQLDPHLRDRLTSDSVTLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQLRVCEGRSLPELGLKQDKIRINGCAIQCRVTTEDPARGFQ-PDTGRLEVFRSAEGM-GIRLDSASAFQGAVISPHYDSLLVKVISSGKDLPTAASKMLRALAEFRIRGVKTNIPFLQNVLSNNQFLHSTVDTQFIDE 409          

Query: 1924 ITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIEL 2232
            + F+  G    + V+  +  K   F  PK + D    + APMPG V  V VK GQ+V  GQ LCVL AMKM+  + +  +G +  V+ +   ++   D+I+E+
Sbjct: 1002 VFFELNGQLRSVLVKDTVAMKEMHFH-PKALKDVRGQVGAPMPGKVVEVKVKQGQKVEKGQPLCVLSAMKMETVVNSPLSGTVAKVYVKTDTSLEGDDLILEI 1103          

Query:  154 WNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEA---VEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAE 1209
            +   HDP E  F KILIANRGEIACR+I +CK+ GI  VAVHSDVDA +  V+MADEA C+GPA T+ SYLNM  ILDAVK +GA+AVHPGYGFLSEN  FAK+L    V F+GP++ A+ +MGDKIESK IA  A V+ IPG+DG + +T +A+KIA +IGYPVMIKASAGGGGKGMRIAWND+E     EG++ S  EA SSFGDDR+LIEK+I+ PRHIEIQ++ D+HGNAL+LNERECS+QRRNQKV+EEAPS F++ +TR+AMGEQAV +A+AV Y SAGTVEFLVD +RNFYFLEMNTRLQVEHPI+E ITG+D+V +M RV  GH L L QS++ + GWA+ECRVYAE
Sbjct:    3 YTATHDPSEKTFDKILIANRGEIACRVIKTCKKMGITTVAVHSDVDANAVHVKMADEAFCVGPAPTAQSYLNMAAILDAVKTSGAQAVHPGYGFLSENKEFAKQLAAEGVKFIGPDTHALQAMGDKIESKLIAKTAGVNTIPGFDGVVKNTKDAVKIAREIGYPVMIKASAGGGGKGMRIAWNDEETNVRREGFRFSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLADEHGNALWLNERECSVQRRNQKVVEEAPSMFLDTQTRRAMGEQAVALARAVRYSSAGTVEFLVDSQRNFYFLEMNTRLQVEHPITECITGLDLVMEMIRVAAGHRLRLSQSEVPIRGWAIECRVYAE 357          

Query:  196 ILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPL 1272
            + I   GEIA R+  +C   GI+ VAV+S+ D      Q ADEA  IG     ++ YL++  I+   ++   +A+HPGYGFLSE + FA+   D ++ F+GP+ + +  MGDK+E++ IA +A V  +PG +  +    EA       G+P++ KA+ GGGG+GMR+  + +E  E ++ + +EA ++FG+  + IEKYI KPRHIE+QI+ DK+GN ++L ER+CSIQRR+QKV+E AP   ++P  R+ +   AV++AK VGY++AGTVEFL+D     YF+E+N+RLQVEH ++E ITGVD+VH    + +G  L    L Q  I +NG A++CRV  EDP + F  P  GR+     P 
Sbjct:    1 VCIVALGEIATRVFRACTELGIRTVAVYSEQDNGQVHRQKADEAYLIGKGLAPVAAYLHIPDIIRVAQENAVDAIHPGYGFLSERSDFAQACLDADIRFIGPSPEVVRQMGDKVEARAIAISAGVPVVPGTEEPVVSLVEARHFCETYGFPIIFKAAFGGGGRGMRVVRSYEELEESFQRAYSEALAAFGNGSLFIEKYIEKPRHIEVQILGDKYGNVVHLYERDCSIQRRHQKVVEIAPGANLDPSMREHLTNDAVKLAKQVGYENAGTVEFLLDKSGRHYFIEVNSRLQVEHTVTEQITGVDLVHSQIHIAEGRSLPSLGLHQDTIRINGCAIQCRVTTEDPARGFQ-PDTGRIEXKVAPF 362          

Query:  196 ILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRL 1251
            + I   GEIA R+  +C   GI+ VAV+S+ D      Q ADEA  IG     ++ YL++  I+   ++   +A+HPGYGFLSE + FA+   D ++ F+GP+ + +  MGDK+E++ IA +A V  +PG +  +    EA       G+P++ KA+ GGGG+GMR+  + +E  E ++ + +EA ++FG+  + IEKYI KPRHIE+QI+ DK+GN ++L ER+CSIQRR+QKV+E AP   ++P  R+ +   AV++AK VGY++AGTVEFL+D     YF+E+N+RLQVEH ++E ITGVD+VH    + +G  L    L Q  I +NG A++CRV  EDP + F  P  GR+
Sbjct:   40 VCIVALGEIATRVFRACTELGIRTVAVYSEQDNGQVHRQKADEAYLIGKGLAPVAAYLHIPDIIRVAQENAVDAIHPGYGFLSERSDFAQACLDADIRFIGPSPEVVRQMGDKVEARAIAISAGVPVVPGTEEPVVSLVEARHFCETYGFPIIFKAAFGGGGRGMRVVRSYEELEESFQRAYSEALAAFGNGSLFIEKYIEKPRHIEVQILGDKYGNVVHLYERDCSIQRRHQKVVEIAPGANLDPSMREHLTNDAVKLAKQVGYENAGTVEFLLDKSGRHYFIEVNSRLQVEHTVTEQITGVDLVHSQIHIAEGRSLPSLGLHQDTIRINGCAIQCRVTTEDPARGFQ-PDTGRI 394          

Query:  190 KKILIANRGEIACRIINSCKRFGIK-----------AVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFL--GPNSKAIHSMGDKIESKRIANAAKVHCIP--GYD------------------------GEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISV-----------------------NGWAVECRVYAEDPYKSFGLPSVG-----RLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRG-VTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHG--LESQDKTQNVHVSVDFDRSHFT--VNFESGNSFRIA-NNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +K+LIAN G  A + + S +R+  +            +    D+ A + +++MAD  + +     + +Y N+E ILD  ++   +AV  G+G  SEN    + L   ++ F+  GP S+A+ S+GDKI S  +A  A +  +P  G+                         G +ND +E +K A  IG+PVMIKAS GGGGKG+R + N +E    ++  +AE   S     + + K  N  RH+E+QI+ D +GNA+ L  R+CSIQRR+QK+IEEAP+T  +    + M + AV++AK VGY SAGTVE+L     +F+FLE+N RLQVEHP +E++  V++     ++  G P L +  DI +                        G  +  R+ +E+P + F  PS G        S K      +V    G+ E      + D       ++GE+R +A++ MV AL    IRG     +  L  ++    F    I T +L  +  +                       V+ E  N T      +L +A+   SFR  +S+   +  S+  G  L +   T +V+V + ++   +T  V  +S +++ +  NN H+  ++    + +  ++L     +++ Y+  +    +Y+L     IG+K   F    +  +  S++ AP  G +    V+ G  V  GQ    +E MKM  SMV  ++G +  V  +PG  +  G ++ +L+
Sbjct:   44 EKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGANNNNYANVELILDIARRIPVQAVWAGWGHASENPKLPELLHKNDIAFMGIGPPSQAMWSLGDKIASSIVAQTANIPTLPWSGFGTFQSWNEADRKGKVINVPPEIYERGCVNDAEEGLKAAQTIGFPVMIKASEGGGGKGIRKSTNAEEFANLFRQVQAEVPGS----PVFVMKLANHARHLEVQILADAYGNAISLFGRDCSIQRRHQKIIEEAPATVAHAHVFQQMEQCAVRLAKMVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMVADVNLPAAQLQISMGIP-LYRIKDIRILYGEPPWGDAPIDFEIPPRTPSPRGHVIAARITSENPDEGFK-PSAGTVQELNFRSNKNVWGYFSVAAAGGLHE------FADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFHENTIDTGWLDRLISEK----------------------VQAERPNTTLGIVSGALHVADG--SFRSSMSN---FLHSLERGQVLPAHTLTNSVNVELIYEGMKYTLKVTRQSPSTYVVTMNNSHM--EVDVHRMSDGGLLLSYDGSSHTTYMKEEV--DRYRLT----IGNKTCVF----EKENDPSILRAPSAGKLIQYMVEDGGHVFVGQCYAEIEVMKMVMSMVVNESGCVHYVK-RPGAVLEPGCVVAKLQ 746          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            PK +      + APMPG V  + VK GQ+V  GQ LCVL AMKM+  + A   G I  +H QP   +   D+I+E+E
Sbjct:  499 PKALKSVKGQVGAPMPGSVIEIKVKEGQQVEKGQPLCVLSAMKMETVVNAPMTGKIIKLHVQPSMHLEGDDLILEIE 575          

Query:  187 FKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRN-FYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYL 1512
            F  +LIANRGEIA RII + K+ GI++VAV+SD D  S+ V  AD ++ +     + +YL+M KI+DA KQT A+A+ PGYGFLSEN  F+       + F+GP+   I  +G K  +++IA  A V  +PG    I   +EA K+A ++ YPVM+K++AGGGG G++   ++++    ++  + + ++ FGD  + +E++I   RH+E+Q+M D  G A+ L ER+CS+QRRNQKVIEE P+  +  +TR A+ + A  +   + Y  AGTVEF+ D+K++ FYFLE+NTRLQVEHPI+E++TG+D+V  M R+          + + VNG ++E R+YAE+P K+F  PS G L   K P      R D+ +++G+ IS  YDP + K++ +G+DR  A++ + +AL+   + G   NI  L+ I+T   F    ++TN L
Sbjct:  633 FDTVLIANRGEIAVRIIKTLKKLGIRSVAVYSDPDKYSQHVTDADVSVPLHGTTAAQTYLDMNKIIDAAKQTNAQAIIPGYGFLSENADFSDACTSAGITFVGPSGDIIRGLGLKHSARQIAQKAGVPLVPG-SLLITSVEEAKKVAAELEYPVMVKSTAGGGGIGLQKVDSEEDIEHIFETVKHQGETFFGDAGVFLERFIENARHVEVQLMGDGFGKAIALGERDCSLQRRNQKVIEETPAPNLPEKTRLALRKAAESLGSLLNYKCAGTVEFIYDEKKDEFYFLEVNTRLQVEHPITEMVTGLDLVEWMIRIAANDAPDFDSTKVEVNGVSMEARLYAENPLKNF-RPSPGLLVDVKFPDW---ARVDTWVKKGTNISPEYDPTLAKIIVHGKDRDDAISKLNQALEETKVYGCITNIDYLKSIITSDFFAKAKVSTNIL 1070          

Query:  193 KILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSL---SYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSG-IQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRS 1647
            KIL+ANRGEI  RI  S     ++ +A++S  D LS     ADEA  IG         +YL M++I++  K+   + +HPGYGFLSEN+ FA K+    + ++GP ++ I S+GDK+ ++ +A  A V  +PG  G I    EA+   N+ GYPV+IKA+ GGGG+GMR+     +  + ++ + +EA+++FG+    +E++++KP+HIE+Q++ D HGN ++L ER+CS+QRR+QKV+E AP+  +  E R A+   AV++AK  GY +AGT EFLVD++   YF+E+N R+QVEH I+E ITG+DIV    ++  G  L    L Q  I+  G++++CR+  EDP K+F  P  GRL  Y+       VR D G    G+ IS +YD M+ K    G         M++AL  + IRGV  NIP L  ++T P F+ G   T ++ +  P  F+      +   LL  ++ +    + I+ +  L K +S
Sbjct:   22 KILVANRGEIPIRIFRSAHELSMRTIAIYSHEDRLSMHRLKADEAYVIGEEGQYTPVGAYLAMDEIIEIAKKHKVDFIHPGYGFLSENSEFADKVVKAGITWIGPPAEVIDSVGDKVSARHLAARANVPTVPGTPGPIETVQEALDFVNEYGYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEVQLLADNHGNVVHLFERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKVCGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITGIDIVSAQIQIAAGATLTQLGLLQDKITTRGFSIQCRITTEDPSKNFQ-PDTGRLEVYRSA-GGNGVRLDGGNAYAGATISPHYDSMLVKCSCSGSTYEIVRRKMIRALIEFRIRGVKTNIPFLLTLLTNPVFIEGTYWTTFIDDT-PQLFQMVSSQNRAQKLLHYLADLAVNGSSIKGQIGLPKLKS 510          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            PK  V  +  I APM G++  V V  G  V  G+ + VL AMKM+  + +   G +K V  + G++V   D+++ LE
Sbjct: 1094 PKADVHDTHQIGAPMAGVIIEVKVHKGSLVKKGESIAVLSAMKMEMVVSSPADGQVKDVFIKDGESVDASDLLVVLE 1170          

Query:  193 KILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSL---SYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLL---LKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSG-IQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRS 1647
            KIL+ANRGEI  RI  +     ++ VA++S  D LS   Q ADEA  IG         +YL +++I+   ++   + +HPGYGFLSEN+ FA K+    + ++GP ++ I S+GDK+ ++ +A  A V  +PG  G I   +EA+   N+ GYPV+IKA+ GGGG+GMR+     +  + ++ + +EA+++FG+    +E++++KP+HIE+Q++ D HGN ++L ER+CS+QRR+QKV+E AP+  +  E R A+   AV++AK  GY +AGT EFLVD++   YF+E+N R+QVEH I+E ITG+DIV    ++  G  L    L Q  I+  G+A++CR+  EDP K+F  P  GR+  Y+       VR D G    G+ IS +YD M+ K    G         M++AL  + IRGV  NIP L  ++T P F+ G   T ++ +  P  F+      +   LL  ++ V    + I+ +  L K +S
Sbjct:   21 KILVANRGEIPIRIFRTAHELSMQTVAIYSHEDRLSTHKQKADEAYVIGEVGQYTPVGAYLAIDEIISIAQKHQVDFIHPGYGFLSENSEFADKVVKAGITWIGPPAEVIDSVGDKVSARNLAAKANVPTVPGTPGPIETVEEALDFVNEYGYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEVQLLADNHGNVVHLFERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKECGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGASLPQLGLFQDKITTRGFAIQCRITTEDPAKNFQ-PDTGRIEVYRSA-GGNGVRLDGGNAYAGTIISPHYDSMLVKCSCSGSTYEIVRRKMIRALIEFRIRGVKTNIPFLLTLLTNPVFIEGTYWTTFIDDT-PQLFQMVSSQNRAQKLLHYLADVAVNGSSIKGQIGLPKLKS 509          

Query:  223 ACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKL--EDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDT-------------------------DEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLV---DDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDI----------------------SVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ------EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRG-VTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKG-KQLTPKETGLL-EAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQ-NVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE*KSTASYSHCKLF 2274
            A    N  K      +A   D+ A S +++MAD+ + +     + +Y N++ ILD  +QT  +AV  G+G  SEN    + L      ++F+GP  +A+ S+GDKI S  +A +AK+ CIP + G   DT                         ++A++ A  IG+PVMIKAS GGGGKG+R   N+ + +  Y+ +  E   S     M + K +   RH+E+Q++ D++G  + L  R+CSIQRR+QK+IEEAP T   PET + M   A+++ + VGY SAGTVE+L    DDK  FYFLE+N RLQVEHP +E+I+GV++     ++  G P+ +  SDI                      S  G  + CR+ +EDP + F  PS G+       +H  N R  S +           I  + D     +   G DR  A   MV AL  + IRG     I  L +++    F S NI+T +L ++         +L P    +   AM A VF + ++RNK               E  R     P+++            KT+  V    D +R  F V   S   F ++ N    + +  Q + +D +++ +  + ++ Y      GT+  +   +I    L   + P +V       I+P PG +    V+ G  V  GQ+   +E MKMQ  +VA   GVI+ +  QPG  +  GD+I +L   S +  +   L+
Sbjct:    8 AYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIP-WSGSHIDTIHIDNKTNFVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGS----PMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDK--FYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMI-SDIRKLYGLDPTGTSYIDFKNLKRPSPKGHCISCRITSEDPNEGFK-PSTGK-------IHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTE-KVRNKYL-------------ELLRRGQVPPKDFL-----------KTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCE-VNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIF---LEAELNPTQV-------ISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLR-QPGSIIEAGDVIAKLTLDSPSKANESSLY 700          

Query:  181 TKFKKILIANRGEIACRIINSCKRFGIK-----------AVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLED--MNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIP----GYD--------------------GEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVD-DKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISV------------------------------NGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ------EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRG-VTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDII 2223
            T   KILIAN G  A + I S +++  +           A+A   D++A + +++MAD+ I +     + +Y N++ I+D  ++   +AV  G+G  SEN +  +KL      V+F+GP   A+ S+GDKI S  +A +AKV CIP    G D                    G     ++ ++ A +IG+PVMIKAS GGGGKG+R    +++ +  Y  +  E   S     + I K   + RH+E+Q++ D++G  + L  R+CS+QRR+QK+IEEAP T    ET   M + AV++ K VGY SAGTVE+L   D   FYFLE+N RLQVEHP +E+++GV++     ++  G P + + SDI                                 G    CR+ +EDP   F  PS G        LH  N R  S +           I  + D     +  +GE+R  +   MV AL    IRG     +  L  ++    F    ITT +L ++       ++  P    +  A +       E R+K       SL   +K +    DL             L++      +H   +  R  FTV     + + +  N    D II + + +  +++ +  ++++ Y   +   T  +L V+S     ++  +   +V +  + +  P PG +    V+ G+ +  GQ    +E MKMQ  +V+ + G+++ +  QPG T+  GDI+
Sbjct:   57 TVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGS----PIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIP-MHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFK-PSGGT-------LHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLITHKMTAEKPDPTLAVICGAATKAFLASEEARHKYI----ESL---QKGQVLSKDL-------------LQTMFPVDFIH---EGKRYKFTVAKSGNDRYTLFINGSKCD-IILRQLSDGGLLIAIGGKSHTIYWKEEVAAT--RLSVDS-----MTTLL---EVENDPTQLRTPSPGKLVKFLVENGEHIIKGQPYAEIEVMKMQMPLVSQENGIVQLLK-QPGSTIVAGDIM 764          

Query:  178 ETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHL-PNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSL--LIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            E  F KILIANRGEIACR++ +C+R GIK VA++S+ DA +  V+MADE++C+GP  T  SYLNM  ILDA++ TGA+AVHPGYGFLSEN  F  +LE+  + F+GPN+KA+H+MGDKIESK I   AKV+ IPG++G +           ++ YPVM+KASAGGGGKGMR+AWND+EA EG++LS  EA SSFGDDR+L+E++I+ PRHIEIQ++ DKHGNA+YLNERECSIQRRNQKVIEEAPS F++P+ R+AMGEQAV +AKAVGYDSAGTVE LVD ++NFYFLEMNTRLQVEHPI+E+ TGVDIV QM RV  G+PL +KQ DI + GWA+E RVYAEDP K+FGLPS+GRL  Y +P H+ PNVRCDSGI EGSEISIYYD MI KL TYGE R +A+  M  ALDSYVIRGVT N+ LLRD++  P+F +G+ITT +LP  YP GFKG  LT KE   L A SA +FV+   R +TF  +  S+  + AE++            W L  S   ES      ++V+   D  +  V   SG          L+  +   N++  +++LQ +S+ +      Q+ GT YK++V +    +L ++M  K   D S  + +PMPG V +V+V VG  V +GQEL V+EAMKMQNS+ +A  G +  V+++ G  V++GDI++++E
Sbjct:   46 EKFFDKILIANRGEIACRVMRTCQRLGIKTVAIYSEADANALHVKMADESVCVGPPPTGASYLNMNAILDAIRSTGAQAVHPGYGFLSENYRFVGRLEEEGITFIGPNAKAMHAMGDKIESKLIGKRAKVNIIPGFEGVV-----------KVSYPVMLKASAGGGGKGMRVAWNDEEAREGFRLSSQEAASSFGDDRLLVERFIDNPRHIEIQVIGDKHGNAVYLNERECSIQRRNQKVIEEAPSPFVDPDMRRAMGEQAVSLAKAVGYDSAGTVECLVDSQKNFYFLEMNTRLQVEHPITEMTTGVDIVEQMIRVAAGYPLPMKQEDIPLKGWAIESRVYAEDPTKNFGLPSIGRLYKYIDPTHISPNVRCDSGIVEGSEISIYYDSMISKLATYGETRDEAIDLMNVALDSYVIRGVTDNVSLLRDVLNHPKFRAGDITTKFLPMEYPKGFKGHVLTEKEREELLATSAYMFVQRVRRARTFKNQSTSVDKVTAEQT-----------SWELVCSLLGESYP----INVTYIGDGKYRMVC--SGEEIEFFAGTPLSAPVFEGNVNGKKVLLQTISK-HGNLFNIQHCGTIYKVRVHTKAEEELMQYMPVKDEEDMSPFLKSPMPGKVVSVAVVVGDEVREGQELAVVEAMKMQNSLHSATTGKVIKVNYKAGDNVAEGDIMVQIE 705          

Query:  193 KILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNS-FRIANNFHL--ADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVS 2208
            KIL+ANRGEIACR++++ +R G++ VAV+S+ DA S  V +ADEA  IGPA +S SYL M KI++  K+TGA+A+HPGYGFLSE+  FA   ++ N++F+GP + AI  MG K  SK I + A V  I GY GE    +   + A +IGYPVM+KA  GGGGKGMRI  +  E  E  + ++ E+  SF DD ML+EK++  PRH+E+Q+  D+ GN +YL ER+CS+QRR+QK+IEEAP+  ++ E R+++GE AV+ AKAVGY  AGTVEF++D  +NFYF+EMNTRLQ +HPI+E+ITG+D+V    ++  G  L LKQ ++ ++G A E RVYAEDP   F LP  G L     P    ++R D+G+++G ++S YYDPMI KLV + E R  AL  + ++L  Y + G+  NI  L  +     F +G++ T+++ +   D F  K   P +  + +A  A++ ++ E RN+       +  +   S SFR         +  +   +   D    + + + ++R   + + E G+  F ++ +        ++T  ++       L+ ++ + ++ F   G +          H+     L   +        APMPG +  V V+ GQ V  GQ L V+EAMKM++S+ + KAGVI  V    G +V+
Sbjct:   37 KILVANRGEIACRVMHTARRMGVQTVAVYSNADAKSLHVSLADEAYRIGPAPSSESYLKMHKIMEVAKKTGAQAIHPGYGFLSESPEFADLCQEENIIFIGPPASAIRDMGIKSTSKSIMSDAGVPIIQGYHGEDQSVERLQQEAERIGYPVMLKAVRGGGGKGMRIVNSPDEFHEMLESAKNESIKSFNDDSMLVEKFVETPRHVEVQVFGDRQGNVVYLYERDCSVQRRHQKIIEEAPAPGVSDEVRRSIGEAAVRAAKAVGYFGAGTVEFIMDSSQNFYFMEMNTRLQAKHPITEMITGLDLVEWQLKIAAGEDLPLKQDEVQLHGHAFEARVYAEDPSSDF-LPGAGPLLHLTTPQETQHIRIDTGVRQGDQVSTYYDPMIAKLVVWSETRPSALRLLKESLKKYNVVGLETNISFLTSLCDHNSFQAGDVHTDFIKQHMADLFPAKGSMPGDD-VAQAGLALLLLEREQRNEKAAASSDTFSLWNTSGSFR--------INSELRRRIRLNDGDAKIEMFITYNRDG-SFDIEIGDELFNVSGSLSREGGKTMLTATVNGRTCKSALVDQDGTLHL-FTKDGCRRL--------HRHVPKYLKSTLGGAVGGAAAPMPGNIVKVLVEPGQEVEQGQVLVVMEAMKMEHSIRSPKAGVIDRVLCSVGGSVT 691          

Query:  193 KILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIG-YPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTP 1557
            KIL+ANRGEIACR++++ +R G++ VAV+SD DA S  V +ADEA  IGPA +S SYL M KI++  K+TGA+A+HPGYGFLSE+  FA   ++ N++F+GP + AI  MG K  SK I + A V   P   G I  +  +I   +    YPVM+KA  GGGGKGMRI  +  E  E  + ++ E+  SF DD ML+EK++  PRH+E+Q+  D+ GN +YL ER+CS+QRR+QK+IEEAP+  ++ E R+++GE AV+ AKAVGY  AGTVEF++D  +NFYF+EMNTRLQ +HPI+E+ITG+D+V    ++  G  L LKQ ++ ++G A E RVYAEDP   F LP  G L     P    ++R D+G+++G ++S YYDPMI KLV + E R  AL  + ++L  Y + G+  NI  L  +     F +G++ T+++ +   D F  K   P
Sbjct:    3 KILVANRGEIACRVMHTARRMGVQTVAVYSDADAKSLHVSLADEAYRIGPAPSSESYLKMHKIMEVAKKTGAQAIHPGYGFLSESPEFADLCQEENIIFIGPPASAIRDMGIKSTSKSIMSDAGV---PIIQGNILSSLLSIHFYSSTSKYPVMLKAVRGGGGKGMRIVNSPDEFHEMLESAKNESIKSFNDDSMLVEKFVETPRHVEVQVFGDRQGNVVYLYERDCSVQRRHQKIIEEAPAPGVSDEVRRSIGEAAVRAAKAVGYFGAGTVEFIMDSSQNFYFMEMNTRLQAKHPITEMITGLDLVEWQLKIAAGEDLPLKQEEVQLHGHAFEARVYAEDPSSDF-LPGAGPLLHLSTPQETQHIRIDTGVRQGDQVSTYYDPMIAKLVVWSETRPSALRLLKESLKKYNVVGLETNISFLTSLCGHNSFQAGDVHTDFIKQHMADLFPAKGSMP 454          

Query:   91 ISLPTLHGSSNKFSSAARNIYWN-DKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHP---LLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCD-SGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFK 1539
             S P    ++ ++  AA  ++ +  K DP + + KKIL+ANRGEIA R+  +    GI+ VA++S+ DA     Q ADEA  +G     ++ YLN+ +I+   K+   +A+HPGYGFLSE   FA       V+F+GP+ + +H MGDK+E++++A  + V  +PG +  I   +EA +   + G PV+ KA+ GGGG+GMR+ W  ++  E + L+  EA ++FGD  M IEK+I KPRHIE+Q+M D +G+ ++L ER+CS+QRR+QKVIE AP+  ++   R+ + E AV++ KAVGY +AGTVEFL+D + N YF+E+N RLQVEH ++E ITGVD+V     V +G     L L Q +I + G A++ RV  EDP  +F  P  GR+  ++    +  +R D S    G+ IS +YD ++ K++ +     +A   + ++L  + +RGV  N   +R+++    F+ G++TT+++ E  PD  K
Sbjct:   17 FSRPAGIQTTCRYIHAANTLHQDAKKRDPPKHEIKKILVANRGEIAIRVFRAATEAGIRTVAIYSEQDANHMHRQKADEAYLVGKGMPPVAAYLNIPEIIRIAKERECDAIHPGYGFLSERADFAHACTKSGVIFIGPSPQVVHMMGDKLEARKMAINSGVPVVPGTENPIRTAEEAKQFCEEHGLPVITKAAYGGGGRGMRVIWKMEDLEEFFNLASNEAYAAFGDGSMFIEKFIEKPRHIEVQVMGDNYGDVVHLFERDCSVQRRHQKVIEIAPAPHLDDAIRQTLTEDAVRLCKAVGYSNAGTVEFLLDQEGNHYFIEVNARLQVEHTVTEEITGVDLVRAQIGVAEGKTLGELGLVQDNIKITGAAIQARVTTEDPANNF-TPDTGRIEVFRSGEGM-GIRLDGSSAFAGAVISPHYDSLLTKVIAHANSHREAATKLHRSLREFRVRGVKTNTEFIRNVLQHKDFLDGHVTTDFILE-NPDMLK 502          

Query: 2005 PKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            PK        + APMPG V  V VK  + V  G  L VL AMKM+ ++ A   G++K +       V  GD++I++E
Sbjct: 1121 PKADKGVKGSVGAPMPGKVVGVRVKENEVVKKGMPLVVLSAMKMETNVSAPIDGIVKKISVSLNSNVEAGDLLIDIE 1197          

Query:  199 LIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHP---LLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCD-SGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFK 1539
            ++ANRGEIA R+  +    GI+ VA++S+ DA     Q ADEA  +G     ++ YLN+ +I+   K    +A+HPGYGFLSE   FA+      ++F+GP+ + +H MGDK+E++++A  A V  +PG    I + ++A     + G PV+ KA+ GGGG+GMR+ WN  +  + + L+  EA ++FGD  M IEK+I KPRHIE+Q+M D +G+ ++L ER+CS+QRR+QKVIE AP+  ++   R+ + E AV++ KAVGY +AGTVEFL+D + N YF+E+N RLQVEH ++E ITG+D+V     V +G     L L Q +I + G A++ RV  EDP  +F  P  GR+  ++    +  +R D S    G+ IS +YD ++ K++ +     +A   + +AL  Y IRGV  N   L +++    F++G + T+++ E  PD  K
Sbjct:    1 MVANRGEIAIRVFRAATEAGIRTVAIYSEQDANHMHRQKADEAYLVGKGMPPVAAYLNIPEIIRIAKDKECDAIHPGYGFLSERADFARACTKSGIIFIGPSPQVVHMMGDKLEARKVAVEAGVPVVPGTAEPIRNAEDARAFCQEHGLPVITKAAYGGGGRGMRVIWNLDDVEKYFTLASNEAYAAFGDGSMFIEKFIEKPRHIEVQVMGDNYGDVVHLFERDCSVQRRHQKVIEIAPAPLLDENIRQTLTEDAVRLCKAVGYSNAGTVEFLLDQEGNHYFIEVNARLQVEHTVTEEITGIDLVRAQIGVAEGKTLGELGLVQDNIKITGAAIQARVTTEDPANNF-TPDTGRIEVFRSGEGM-GIRLDGSSAFAGAVISPHYDSLLTKVIAHASSHREAATKLHRALTEYRIRGVKTNTSFLMNVLKHDSFLNGTVNTDFILE-NPDLLK 449          

Query: 2041 APMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            APMPG V  V VK  + V  G  L VL AMKM+ ++ A   G +K +      +++ GD+++ELE
Sbjct: 1073 APMPGKVVAVRVKENEVVKKGTSLVVLSAMKMETNVSAPIDGRVKKISVSQNMSLNAGDLLVELE 1137          

Query:  115 SSNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            S  ++SS+ R        + +E  F+K+LIANRGEIACR+I +CKR GI+ +AVHSDVD+ +  V+MADEA+C+GPA TSLSYLNM+ IL+AV++TGA+AVHPGYGFLSEN  FAK+L   +V F+GP++ AI +MGDKI+SK IA AAKV+ IPG+DG +   ++A+KIA QIGYPVMIKASAGGGGKGMRIAWND+E  EG++ S  EA SSFGDDR+LIEKYI++PRHIEIQ++ DKHGNAL+LNERECSIQRRNQKV+EEAPSTF++P TR+AMGEQAVQ+AKAV Y SAGTVEFLVD ++NFYFLEMNTRLQVEHPI+E ITG+D+V QM RV KG+ L  KQ DI +NGWA+E RVYAEDP+KSFGLPS+GRL+ Y+EPL L NVR DSGI+EGS+ISIYYDPMI KLVT+G  R++ALA M ++LD YVIRGVTHNIPLLR+I+T P F+SG+I+TN+LPEVYP+GFKG QL  ++   L A +A + +  ++R+++ L   R       S S  G  S    W LS+  G    ++  +VH++     S +TV  + G    +   ++LA  ++   I+  + +LQ +SR  SG I  Q+MGT +K++V S +  KL+ +M  K   DTSS++ +PMPG V  VSV  G  V++GQE+CV+EAMKMQNS+ A K   +K+VH +PG+TV +GD+++ELE
Sbjct:   31 SRAQYSSSCR------PEEEQEETFQKLLIANRGEIACRVIKTCKRMGIQTIAVHSDVDSNAVHVKMADEAVCVGPAPTSLSYLNMDAILNAVRRTGAQAVHPGYGFLSENKEFAKRLAAEDVTFIGPDTHAIQAMGDKIQSKLIAKAAKVNTIPGFDGVVKSAEDAVKIAQQIGYPVMIKASAGGGGKGMRIAWNDEETREGFRFSSQEAASSFGDDRLLIEKYIDRPRHIEIQVLADKHGNALWLNERECSIQRRNQKVVEEAPSTFLDPTTRRAMGEQAVQLAKAVQYSSAGTVEFLVDAQKNFYFLEMNTRLQVEHPITECITGLDLVEQMIRVAKGYRLQHKQEDIPINGWAIESRVYAEDPFKSFGLPSIGRLSQYQEPLDLSNVRVDSGIEEGSDISIYYDPMISKLVTFGATRAEALARMEESLDRYVIRGVTHNIPLLREIITHPLFISGDISTNFLPEVYPEGFKGHQLEAEQRRELLASAAALHIAAQLRSQSILGNLRV------SSSVAGHSS----WDLSLELG----ERHYDVHITK--SGSIYTVEVDGGR-VEVIGEWNLASPLLPLTINGSQRMLQCLSREASGTIALQFMGTLFKVRVLSKLASKLNSYMPEKLPEDTSSILRSPMPGTVVAVSVHPGDTVAEGQEICVIEAMKMQNSLTAVKQAKVKSVHCKPGETVGEGDLLVELE 714          

Query:   88 FISLPTLHGS---SNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGF 1536
             +S PTL G      K + + R++         E + +K+LIANRGEIACR++ + K+ G+++VAV+S+ D  S  V MADEA  IGP  +  SYL++EK+L+  K++G+ AVHPGYGFLSENT FA+  +   ++F+GP S AI  MG K  SK I +AA V  I GY GE    +  +  A +IG+PVMIKA  GGGGKGMRIA ++ + +E  + +R EA+ SF DD ML+EK++  PRH+E+Q+  D HGNA+YL ER+CS+QRR+QK+IEEAP   I+PE RK +GE AV+ AKAV Y  AGTVEF+VD + NFYF+EMNTRLQVEHP++E+ITG D+V    RV  G  L L Q DI + G + E R+YAEDP   F LP  G L     P    + R ++G++EG E+S +YDPMI KLV +GEDRS AL  +   L  Y I G+  NI  L  +   P F +GN++T+++P+ Y D F
Sbjct:    5 ILSFPTLCGLRILPRKLTWSRRSVRLASGGGGVE-RIEKVLIANRGEIACRVMRTAKKMGVRSVAVYSEADKSSMHVAMADEAYHIGPPPSQQSYLSVEKVLEVAKKSGSHAVHPGYGFLSENTEFAEACKREGIIFIGPPSSAIRDMGIKSTSKHIMSAAGVPIIGGYHGEDQSNERLLAEAAKIGFPVMIKAVRGGGGKGMRIARSETDFLEQLESARREARKSFNDDVMLVEKFVEDPRHVEVQVFGDTHGNAVYLFERDCSVQRRHQKIIEEAPGPGISPEVRKKLGEAAVRAAKAVNYVGAGTVEFIVDAQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGERLPLLQDDIILRGHSFEARIYAEDPNNEF-LPGAGPLLHLSTPPADRHTRIETGVREGDEVSAHYDPMIAKLVVWGEDRSAALKKLRYCLRQYNIVGLNTNIDFLLSLSGHPEFEAGNVSTSFIPQHYSDLF 488          

Query:  184 KFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGF 1536
            + +K+LIANRGEIACR++ + K+ G+++VAV+S+ D  S  V MADEA  IGP  +  SYL++EK+L+  K++G+ AVHPGYGFLSENT FA+  +   ++F+GP S AI  MG K  SK I +AA V  I GY GE    +  +  A +IG+PVMIKA  GGGGKGMRIA ++ + +E  + +R EA+ SF DD ML+EK++  PRH+E+Q+  D HGNA+YL ER+CS+QRR+QK+IEEAP   I+PE RK +GE AV+ AKAV Y  AGTVEF+VD + NFYF+EMNTRLQVEHP++E+ITG D+V    RV  G  L L Q DI + G + E R+YAEDP   F LP  G L     P    + R ++G++EG E+S +YDPMI KLV +GEDRS AL  +   L  Y I G+  NI  L  +   P F +GN++T+++P+ Y D F
Sbjct:   21 RIEKVLIANRGEIACRVMRTAKKMGVRSVAVYSEADKSSMHVAMADEAYHIGPPPSQQSYLSVEKVLEVAKKSGSHAVHPGYGFLSENTEFAEACKREGIIFIGPPSSAIRDMGIKSTSKHIMSAAGVPIIGGYHGEDQSNERLLAEAAKIGFPVMIKAVRGGGGKGMRIARSETDFLEQLESARREARKSFNDDVMLVEKFVEDPRHVEVQVFGDTHGNAVYLFERDCSVQRRHQKIIEEAPGPGISPEVRKKLGEAAVRAAKAVNYVGAGTVEFIVDAQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGERLPLLQDDIILRGHSFEARIYAEDPNNEF-LPGAGPLLHLSTPPADRHTRIETGVREGDEVSAHYDPMIAKLVVWGEDRSAALKKLRYCLRQYNIVGLNTNIDFLLSLSGHPEFEAGNVSTSFIPQHYSDLF 470          

Query:  190 KKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLS-YLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQ-EGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVV 1596
            KK+++ANRGEIA R+  +C   GI+ VAV+S+ D      Q ADEA  IG     ++ YL++  I+   K+ G +A+HPGYGFLSE   FA+   D  V F+GP    +  MGDK+E++ +AN+A V  +PG D  I+   +A   A   G+P++ KA+ GGGG+GMR+    +E  E Y+ + +EA ++FG+  + +EK+I KPRHIE+QI+ DK+GN ++L ER+CSIQRR+QKV+E AP   ++P  R  +   AV +AK VGY++AGTVEFLVD     YF+E+N+RLQVEH ++E IT    V Q+FR G+G                                                 +R DS    +G+ IS +YD ++ K++  G+D + A + M +AL  + +RGV  NIP L+++++  +F+   + T ++ E  P+ F  K    +   LL  +  V+
Sbjct:   38 KKVMVANRGEIAIRVFRACTEMGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLPPVAAYLHIPDIIKVAKENGVDAIHPGYGFLSERADFAQACADAGVRFVGPTPDTVRKMGDKVEARSLANSAGVPVVPGTDAPISCLQDAQAFAQTYGFPIIFKAAYGGGGRGMRVVREYEELEENYQRAYSEALTAFGNGALFVEKFIEKPRHIEVQILGDKYGNVIHLYERDCSIQRRHQKVVEIAPGFQLDPHLRDRLHSDAVNLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDKPFVLQVFRSGEGM-----------------------------------------------GIRLDSASAFQGAIISPHYDSLLVKVIASGKDLNTAASKMSRALAEFRVRGVKTNIPFLQNVLSNNQFLHSTVDTQFIDE-NPELFNLKPTQNRAQKLLHYLGHVM 460          

Query: 1900 MSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            +++N    + F+  G    + V+  +  K  KF  PK        + APMPG V  V VK G +V  GQ LCVL AMKM+  + +  AG IKA+H  P  ++   D+I+E+E
Sbjct:  937 LNKNGQREVFFEMNGQLRSVLVKDTVAMKEMKFH-PKAQKSIKGQVGAPMPGKVLEVKVKTGSKVEKGQPLCVLSAMKMETVVNSPMAGTIKAIHVSPDASLEGDDLILEIE 1047          

Query:  190 KKILIANRGEIACRIINSCKRFGIK-----------AVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGY---------------------------DGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHP--------LLLKQS---DISVN-----------GWAVECRVYAEDPYKSFGLPSVGRLT-----SYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRG-VTHNIPLLRDIVTEPRFVSGNITTNYL 1512
            +K+LIAN G  A + + S +R+  +            +    D+ A + +++MAD  + +     + +Y N+E I+D  K+   + V  G+G  SEN    + L    + FLGP+SKA+ ++GDK+ S  +A +A +  +P                             +G + D ++ +  A +IGYPV+IKAS GGGGKG+R   N ++    ++  + E   S     + + +     RH+E+QI+ D++GNA+ L  R+CSIQRR+QK+IEEAP+T     T + M + AV+MAK VGY SAGTVE+L  +  +F+FLE+N RLQVEHP +E+I  V++     ++  G P        LL  +S   D  +N           G  +  R+ +E+P + F  PS G +      S K      +V    G+ E      + D       ++GE+R +A++ MV AL    IRG     +  L  I+    + +  I T +L
Sbjct:  198 EKVLIANNGIAAVKCMRSIRRWSYEMFRNERTIRFVVMVTPEDLKANAEYIKMADHYVPVPGGSNNNNYANVELIVDIAKRIPVQGVWAGWGHASENPKLPELLHKAGISFLGPSSKAMWALGDKVASSIVAQSADIPTLPWSGSGLKVDWTEEDQTQGKVISVPPEVYNEGCVRDVEDGLAGAERIGYPVVIKASEGGGGKGIRKVENSEDFPGFFRQVQTEVPGS----PIFVMQLAQHARHLEVQILADEYGNAISLFGRDCSIQRRHQKIIEEAPATIAASSTLEQMEQYAVRMAKMVGYVSAGTVEYLYSEDGSFHFLELNPRLQVEHPCTEMIGDVNLPAAQLQIAMGIPLSRIKDIRLLYGESPWGDTHINFEVPYRLPSPRGHVIAVRITSENPDEGFK-PSSGTVQELNFRSSKNVWGYFSVGATGGLHE------FADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKILETESYRNNEIDTGWL 693          

Query:   70 MLRIKCFISLPTLHGSSNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            MLRIKCFISLPTLHGSSNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE
Sbjct:    1 MLRIKCFISLPTLHGSSNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 722          

Query:   70 MLRIKCFISLPTLHGSSNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            MLRIKCFISLPTLHGSSNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDR         SFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE
Sbjct:    1 MLRIKCFISLPTLHGSSNKFSSAARNIYWNDKHDPKETKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPLLLKQSDISVNGWAVECRVYAEDPYKSFGLPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDR---------SFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFDRSHFTVNFESGNSFRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 713          

Query:  181 TKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPL-LLKQSDISVNGWAVECRVYAEDPYKSFG-LPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFD---RSHF--TVNFESGNS--FRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            T+  KILIANRGEIACR+I + KR GI+ +AV+S+ D  S   +MA ++ CIGPA + LSYLN EK+L   + T ++A+HPGYGFLSEN  FA   +  NV+F+GP   AI  MG K  SK I  AA V  + GY G   + D  ++ A +IG+P+MIKA  GGGGKGMRI  +  E  E  + ++ EA  SF DD ML+EK+I  PRH+E+Q+                       K+IEEAP   I  E R  +G+ AV+ A AV Y  AGTVEF++D K NFYF+EMNTRLQVEHPI+E+ITG D+V    RV  G  L ++ Q+ I   G A E R+YAED       +P+ G +   + P    NVR D+G+ EG EIS++YDPMI KLV +  DRS AL  +  AL+SY I G+  NI  L+ +   P F+ G + T+++ +     F  ++   ++  +  A+S ++  ++ I   +   +DR    A +   FR  ++H  +  +  +H      K+    + V+ D    S+F  TVN E       RI  N       I  ++D  +  + +       ++ F     K++L    +    L    L +   D S   I+PMPG+++ + V+VGQ+++ G+ L  L AMKM+  + A   G++++++   G+TV+    ++EL+
Sbjct:    4 TRISKILIANRGEIACRVIKTAKRMGIETIAVYSEADRNSLHAKMASQSYCIGPAASQLSYLNAEKLLSVAQMTKSQAIHPGYGFLSENVEFAALCKANNVIFIGPPESAIRDMGIKNTSKSIMEAAGVPVVKGYHGNNQNKDYLLEEATKIGFPIMIKAVRGGGGKGMRICLSKNEFFEQLESAKREAIKSFNDDAMLLEKFIETPRHVEVQVFGIV------------------TKIIEEAPGPGITAEIRDRLGKAAVKAAAAVSYVGAGTVEFIMDAKHNFYFMEMNTRLQVEHPITEMITGTDLVEWQLRVASGERLPIIDQALIQPKGHAFEARIYAEDCTNPTAFMPTAGLIKHMRLPEINENVRIDTGVLEGDEISVHYDPMISKLVVWSHDRSSALQKLTMALNSYQIVGLPTNIEFLKSLSLHPSFIDGLVHTDFIKQHTDSLFAVEKSETRDVSIAAAVSVMIDSQHPIVIDS--SEDRYSPFATQLPGFR--INHNFQQKIKFNH------KSMISEMIVERDTHSNSYFVSTVNGEQKTLKISRIVENHETNPNRIRLDVDGIQTDVSMFRDGLDLHLFFD---GKHELFTYCVDELALGSATLVENAGDGSLFGISPMPGVIEKIFVEVGQKITRGESLLTLIAMKMEYIIRAGSDGIVQSINVSEGETVAKNIHLVELK 666          

Query:  181 TKFKKILIANRGEIACRIINSCKRFGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPL-LLKQSDISVNGWAVECRVYAEDPYKSFG-LPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFD---RSHF--TVNFESGNS--FRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
            T+  KILIANRGEIACR+I + KR GI+ +AV+S+ D  S   +MA ++ CIGPA + LSYLN EK+L   + T ++A+HPGYGFLSEN  FA                                     C   Y G   + D  ++ A +IG+P+MIKA  GGGGKGMRI  +  E  E  + ++ EA  SF DD ML+EK+I  PRH+E+Q+  D +GN ++L ER+CS+QRR+QK+IEEAP   I  E R  +G+ AV+ A AV Y  AGTVEF++D K NFYF+EMNTRLQVEHPI+E+ITG D+V    RV  G  L ++ Q+ I   G A E R+YAED       +P+ G +   + P    NVR D+G+ EG EIS++YDPMI KLV +  DRS AL  +  AL+SY I G+  NI  L+ +   P F+ G + T+++ +     F  ++   ++  +  A+S ++  ++ I   +   +DR    A +   FR  ++H  +  +  +H      K+    + V+ D    S+F  TVN E       RI  N       I  ++D  +  + +       ++ F     K++L    +    L    L +   D S   I+PMPG+++ + V+VGQ+++ G+ L  L AMKM+  + A   G++++++   G+TV+    ++EL+
Sbjct:    4 TRISKILIANRGEIACRVIKTAKRMGIETIAVYSEADRNSLHAKMASQSYCIGPAASQLSYLNAEKLLSVAQMTKSQAIHPGYGFLSENVEFAAL-----------------------------------C---YHGNNQNKDYLLEEATKIGFPIMIKAVRGGGGKGMRICLSKNEFFEQLESAKREAIKSFNDDAMLLEKFIETPRHVEVQVFGDSYGNYVHLCERDCSVQRRHQKIIEEAPGPGITAEIRDRLGKAAVKAAAAVSYVGAGTVEFIMDAKHNFYFMEMNTRLQVEHPITEMITGTDLVEWQLRVASGERLPIIDQALIQPKGHAFEARIYAEDCTNPTAFMPTAGLIKHMRLPEINENVRIDTGVLEGDEISVHYDPMISKLVVWSHDRSSALQKLTMALNSYQIVGLPTNIEFLKSLSLHPSFIDGLVHTDFIKQHTDSLFAVEKSETRDVSIAAAVSVMIDSQHPIVIDS--SEDRYSPFATQLPGFR--INHNFQQKIKFNH------KSMISEMIVERDTHSNSYFVSTVNGEQKTLKISRIVENHETNPNRIRLDVDGIQTDVSMFRDGLDLHLFFD---GKHELFTYCVDELALGSATLVENAGDGSLFGISPMPGVIEKIFVEVGQKITRGESLLTLIAMKMEYIIRAGSDGIVQSINVSEGETVAKNIHLVELK 646          

Query:  253 FGIKAVAVHSDVDALSRFVQMADEAICIGPAQTSLSYLNMEKILDAVKQTGAEAVHPGYGFLSENTVFAKKLEDMNVVFLGPNSKAIHSMGDKIESKRIANAAKVHCIPGYDGEINDTDEAIKIANQIGYPVMIKASAGGGGKGMRIAWNDKEAVEGYKLSRAEAKSSFGDDRMLIEKYINKPRHIEIQIMCDKHGNALYLNERECSIQRRNQKVIEEAPSTFINPETRKAMGEQAVQMAKAVGYDSAGTVEFLVDDKRNFYFLEMNTRLQVEHPISELITGVDIVHQMFRVGKGHPL-LLKQSDISVNGWAVECRVYAEDPYKSFG-LPSVGRLTSYKEPLHLPNVRCDSGIQEGSEISIYYDPMICKLVTYGEDRSKALATMVKALDSYVIRGVTHNIPLLRDIVTEPRFVSGNITTNYLPEVYPDGFKGKQLTPKETGLLEAMSAVVFVKNEIRNKTFLKKDRSLLIAEKSESFRGDLSHPEEWHLSISHGLESQDKTQNVHVSVDFD---RSHF--TVNFESGNS--FRIANNFHLADKIITQNIDNDEIILQLMSRNYSGYITFQYMGTKYKLKVESIIGHKLSKFMLPKKVVDTSSVIIAPMPGLVKTVSVKVGQRVSDGQELCVLEAMKMQNSMVAAKAGVIKAVHFQPGQTVSDGDIIIELE 2235
             GI+ +AV+S+ D  S   +MA ++ CIGPA + LSYLN EK+L   + T ++A+HPGYGFLSEN  FA   +  NV+F+GP   AI  MG K  SK I  AA V  + GY G   + D  ++ A +IG+P+MIKA  GGGGKGMRI  +  E  E  + ++ EA  SF DD ML+EK+I  PRH+E+Q+                       K+IEEAP   I  E R  +G+ AV+ A AV Y  AGTVEF++D K NFYF+EMNTRLQVEHPI+E+ITG D+V    RV  G  L ++ Q+ I   G A E R+YAED       +P+ G +   + P    NVR D+G+ EG EIS++YDPMI KLV +  DRS AL  +  AL+SY I G+  NI  L+ +   P F+ G + T+++ +     F  ++   ++  +  A+S ++  ++ I   +   +DR    A +   FR  ++H  +  +  +H      K+    + V+ D    S+F  TVN E       RI  N       I  ++D  +  + +       ++ F     K++L    +    L    L +   D S   I+PMPG+++ + V+VGQ+++ G+ L  L AMKM+  + A   G++++++   G+TV+    ++EL+
Sbjct:    1 MGIETIAVYSEADRNSLHAKMASQSYCIGPAASQLSYLNAEKLLSVAQMTKSQAIHPGYGFLSENVEFAALCKANNVIFIGPPESAIRDMGIKNTSKSIMEAAGVPVVKGYHGNNQNKDYLLEEATKIGFPIMIKAVRGGGGKGMRICLSKNEFFEQLESAKREAIKSFNDDAMLLEKFIETPRHVEVQVFGIV------------------TKIIEEAPGPGITAEIRDRLGKAAVKAAAAVSYVGAGTVEFIMDAKHNFYFMEMNTRLQVEHPITEMITGTDLVEWQLRVASGERLPIIDQALIQPKGHAFEARIYAEDCTNPTAFMPTAGLIKHMRLPEINENVRIDTGVLEGDEISVHYDPMISKLVVWSHDRSSALQKLTMALNSYQIVGLPTNIEFLKSLSLHPSFIDGLVHTDFIKQHTDSLFAVEKSETRDVSIAAAVSVMIDSQHPIVIDS--SEDRYSPFATQLPGFR--INHNFQQKIKFNH------KSMISEMIVERDTHSNSYFVSTVNGEQKTLKISRIVENHETNPNRIRLDVDGIQTDVSMFRDGLDLHLFFD---GKHELFTYCVDELALGSATLVENAGDGSLFGISPMPGVIEKIFVEVGQKITRGESLLTLIAMKMEYIIRAGSDGIVQSINVSEGETVAKNIHLVELK 639