Phosphatidylinositol 4-phosphate 5-kinase 2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031461 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Human
Match: MORN1 (MORN repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25852]) HSP 1 Score: 234.572 bits (597), Expect = 3.968e-70 Identity = 141/444 (31.76%), Postives = 225/444 (50.68%), Query Frame = 1
Query: 130 GFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMK-LTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSL-FELIEQIDSKPVETTYYPVLLVPLTDKPPQW----VQSLENASHNKIRLPHL-FESDESNSQPPESTETDLTD---APLCNDLCLDPVIQETKNGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASV-------SATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
G+GVYVY N FF+YEGEW+ G+KHGHG+ + DGS+YEG F +GEI G+G R+W +G+ + G+F GE G G+M Y G Y G+ REG+G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y+GQ++ ++F G G++ H G+ Y GLW P + T++ L ++++ QG F +++ L+ D+GEI ESGR L+++AGV+Y ++ + + F +++ + + + T + +P P ++ + + + LP E E T L AP C C Q + G +F ++ + P L DS + S + + ++ S E ++ LGEYVL+I D+T PF+ RL + +++
Sbjct: 26 GYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVNVQLLQDHGEIAKSESGRVLQISAGVRYVQLSAYSEVNFFKVDRDNQETLIQTPFGFECIPYPVSSPAAGVPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARGHAPHCPGAC-----QRVEQGCAEFTDVLLGPPPPGYHPFLFLDSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRPEGRATEEQA---AAAHLGEYVLMIRDVTTPPFLGRRLPPAFKHLRV 461
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Human
Match: MORN1 (MORN repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25852]) HSP 1 Score: 213.386 bits (542), Expect = 9.236e-64 Identity = 104/238 (43.70%), Postives = 152/238 (63.87%), Query Frame = 1
Query: 130 GFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMK-LTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKY 840
G+GVYVY N FF+YEGEW+ G+KHGHG+ + DGS+YEG F +GEI G+G R+W +G+ + G+F GE G G+M Y G Y G+ REG+G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y+GQ++ ++F G G++ H G+ Y GLW P + T++ L ++++ QG F +++ L+ D+GEI ESGR L+++AGV+Y
Sbjct: 26 GYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVNVQLLQDHGEIAKSESGRVLQISAGVRY 263
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Human
Match: MORN1 (MORN repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:25852]) HSP 1 Score: 105.145 bits (261), Expect = 6.538e-26 Identity = 56/130 (43.08%), Postives = 77/130 (59.23%), Query Frame = 1
Query: 202 GHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYE 591
GHG+ + DGS+YEG F +GEI G+G R+W +G+ + G+F GE G G+M Y G Y G+ REG+G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y+
Sbjct: 26 GHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYK 155 HSP 2 Score: 57.3806 bits (137), Expect = 3.107e-9 Identity = 35/95 (36.84%), Postives = 53/95 (55.79%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYE 453
+ G++ G+ G+G G YEGE +G G G + G VY+G FH+ + G G M + NGD+Y GDW+ + R+G+G L A+G Y+
Sbjct: 62 FSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLV-DRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYK 155 HSP 3 Score: 57.3806 bits (137), Expect = 3.837e-9 Identity = 40/139 (28.78%), Postives = 64/139 (46.04%), Query Frame = 1
Query: 343 GTGIMFYGNGDEYHGDWISNSREGNGQLTYA-NGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQI 756
G G + + +G Y G ++ G G+ +A +GD + G+F + G G+M G Y G G + GHG + DG VY+G F+ N HG G + G Y G W ++ + +L C G T+++
Sbjct: 26 GHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRD--------RRQGHGVLRCADGSTYKL 156
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Human
Match: AC084018.3 (MORN repeat-containing protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q6PF18]) HSP 1 Score: 99.7525 bits (247), Expect = 4.528e-23 Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD-GSVYEGQFNYNL 612
++Y+GE ++ G G V++ K YEG+W+ GK+ G+G + D + GK R VY G + + +G GI F+G + Y GDW + R G G++ Y+NGD+YEG++ K +GEG++RL NG+ Y G W G K+G G+ D G ++EG + N+
Sbjct: 36 DYYVGEWKDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPD-----------QQTGKCRR-------VYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWVDNM 192 HSP 2 Score: 55.0694 bits (131), Expect = 8.518e-8 Identity = 40/138 (28.99%), Postives = 64/138 (46.38%), Query Frame = 1
Query: 295 KTGNVYRGEFHNGEMTGTGIMFYG-NGDEYHGDWISNSREGNG-QLTYANGDVYEGEFYKHKIHGEGIMRLMN------GSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLP 684
K+ ++++G + G Y NGD Y G+W N + G G Q+ G +YEG++ K G G + L + +YSG+W K G+G YEG + + G G +++ G +Y G WE + P
Sbjct: 9 KSESLWKGWDRKAQRNGLRSQVYAVNGDYYVGEWKDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKP 146
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Human
Match: AC084018.3 (MORN repeat-containing protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q6PF18]) HSP 1 Score: 99.7525 bits (247), Expect = 4.528e-23 Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD-GSVYEGQFNYNL 612
++Y+GE ++ G G V++ K YEG+W+ GK+ G+G + D + GK R VY G + + +G GI F+G + Y GDW + R G G++ Y+NGD+YEG++ K +GEG++RL NG+ Y G W G K+G G+ D G ++EG + N+
Sbjct: 36 DYYVGEWKDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPD-----------QQTGKCRR-------VYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWVDNM 192 HSP 2 Score: 55.0694 bits (131), Expect = 8.518e-8 Identity = 40/138 (28.99%), Postives = 64/138 (46.38%), Query Frame = 1
Query: 295 KTGNVYRGEFHNGEMTGTGIMFYG-NGDEYHGDWISNSREGNG-QLTYANGDVYEGEFYKHKIHGEGIMRLMN------GSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLP 684
K+ ++++G + G Y NGD Y G+W N + G G Q+ G +YEG++ K G G + L + +YSG+W K G+G YEG + + G G +++ G +Y G WE + P
Sbjct: 9 KSESLWKGWDRKAQRNGLRSQVYAVNGDYYVGEWKDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKP 146
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Celegans
Match: jph-1 (JunctoPHilin [Source:UniProtKB/TrEMBL;Acc:Q22667]) HSP 1 Score: 50.8322 bits (120), Expect = 2.187e-6 Identity = 41/141 (29.08%), Postives = 64/141 (45.39%), Query Frame = 1
Query: 208 GRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNG-SIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEG 627
GRF DG Y G ++ G+ G G P+ Y G +H G +G+ + +G+ Y G W + R G G + +Y+GE+ + G+ + N + Y G W G G+G D Y+GQ+ + HG G
Sbjct: 4 GRFDFDDGGTYVGGWEEGKAHGHGVCTGPQAKGEYAGAWHYG-FEVSGVYTWPSGNTYQGQWQNGKRHGLG-IEQRGRWLYKGEWTQGYKGRYGVRQSANSQARYQGTWSAGFHDGYGTEIYVDSGSYQGQWLRGMRHGYG 142
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Fly
Match: CG30429 (gene:FBgn0050429 transcript:FBtr0072450) HSP 1 Score: 73.9442 bits (180), Expect = 3.291e-14 Identity = 45/134 (33.58%), Postives = 71/134 (52.99%), Query Frame = 1
Query: 292 PKTGNVYRGEFHNGEMTGTGIMFYGNGDE----YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLWEQN 678
P+ +Y G++ + G G M G E Y G W + + G G+ Y++G VY G++ K++ HG GI +G+IY+G W +HG G M +G+ YEG F +GEG +H+ G + G+WE +
Sbjct: 63 PEGQLIYEGDWVMNKRQGVGSMLRKRGTEVQLIYSGRWYDDMKCGEGKQFYSDGCVYFGKWIKNRRHGLGIQWYNDGNIYAGEWETDFRHGLGVMFYANGNRYEGHFARGYKNGEGVFYHMHTGQIQKGMWEND 196 HSP 2 Score: 51.6026 bits (122), Expect = 7.353e-7 Identity = 41/129 (31.78%), Postives = 55/129 (42.64%), Query Frame = 1
Query: 349 GIMFYGNGDEYHGDWISNSREGNG---------QLTYANGD-----VYEGEFYKHKIHGEGIMRLMNGS----IYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNL 681
+Y G Y G W+ N +G G Q Y +YEG++ +K G G M G+ IYSG W K G GK DG VY G++ N HG G ++ G +Y G WE +
Sbjct: 22 ATFYYPGGGSYSGYWLCNKHQGWGVKKTAKRTCQYFYGKKHPEGQLIYEGDWVMNKRQGVGSMLRKRGTEVQLIYSGRWYDDMKCGEGKQFYSDGCVYFGKWIKNRRHGLGIQWYNDGNIYAGEWETDF 150
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Fly
Match: CG5458 (gene:FBgn0032478 transcript:FBtr0080437) HSP 1 Score: 73.9442 bits (180), Expect = 5.874e-14 Identity = 46/140 (32.86%), Postives = 69/140 (49.29%), Query Frame = 1
Query: 94 FYIGETNKM-LREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNG 510
YIG N R+G G + N +Y+G ++KG++HG G +V DGS Y G+++ G+ CG+ GI Y +G Y G+W N + G G+ Y NGD Y G+++K + HG GI +G
Sbjct: 26 LYIGGRNAAGQRQGRGWAILPNGD-QYDGNYRKGRRHGIGVYVFKDGSRYYGQYRCGKRCGR------------------------GIFIYPDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDWFKGQRHGVGIYHFNSG 140 HSP 2 Score: 73.559 bits (179), Expect = 7.376e-14 Identity = 37/91 (40.66%), Postives = 51/91 (56.04%), Query Frame = 1
Query: 397 SNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLW 669
+ R+G G NGD Y+G + K + HG G+ +GS Y G + CG + G G PDGSVYEG + NL HG+G ++ G Y+G W
Sbjct: 34 AGQRQGRGWAILPNGDQYDGNYRKGRRHGIGVYVFKDGSRYYGQYRCGKRCGRGIFIYPDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDW 124 HSP 3 Score: 67.0106 bits (162), Expect = 9.633e-12 Identity = 49/163 (30.06%), Postives = 73/163 (44.79%), Query Frame = 1
Query: 229 GSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGS-------VYEGQFNYNLFHGEGTLF----HICGILYTGLWEQNLP 684
G + G G+ G+G P G+ Y G + G G G+ + +G Y+G + R G G Y +G VYEG + K+ HG+G + +NG YSG W G +HG G G + +N N+ G L+ C IL+ G+W+ P
Sbjct: 25 GLYIGGRNAAGQRQGRGWAILP-NGDQYDGNYRKGRRHGIGVYVFKDGSRYYGQYRCGKRCGRGIFIYPDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDWFKGQRHGVGIYHFNSGKDGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTILH-GIWDNLYP 185 HSP 4 Score: 57.3806 bits (137), Expect = 1.307e-8 Identity = 37/117 (31.62%), Postives = 52/117 (44.44%), Query Frame = 1
Query: 292 PKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI 642
P G G G+ G G NGD+Y G++ R G G + +G Y G++ K G GI +GS+Y G W KHG G+ +G Y G + HG G ++H
Sbjct: 22 PNIGLYIGGRNAAGQRQGRGWAILPNGDQYDGNYRKGRRHGIGVYVFKDGSRYYGQYRCGKRCGRGIFIYPDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDWFKGQRHGVG-IYHF 137
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Fly
Match: CG14490 (gene:FBgn0034281 transcript:FBtr0086801) HSP 1 Score: 68.9366 bits (167), Expect = 3.738e-13 Identity = 47/143 (32.87%), Postives = 72/143 (50.35%), Query Frame = 1
Query: 130 GFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHG 558
GFGV + YEG WQKG++HG G + E+ G+ ER +Y G++ + +G G FY +G Y G W+++ R G G L A+G +Y GE+ + K+H +G++ G+ Y G + G K G G
Sbjct: 33 GFGVKQTSSGLV-YEGHWQKGQRHG------------IGSLRRKELDGRMER-------IYVGQWRENKRSGEGKQFYPDGSVYFGQWLADQRSGEGILWQADGGIYVGEWLRDKMHEKGLLFTATGNRYVGQFEGGCKSGSG 155 HSP 2 Score: 66.2402 bits (160), Expect = 3.467e-12 Identity = 52/177 (29.38%), Postives = 78/177 (44.07%), Query Frame = 1
Query: 166 KYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICG--ILYTGLWEQNLPCK 690
+Y+G+W + HG G + G YEG +Q G+ G G++ R E +G M Y G W N R G G+ Y +G VY G++ + GEGI+ +G IY G W+ H G + G+ Y GQF G G +H + G W +++ C+
Sbjct: 21 QYQGKWLGQQPHGFGVKQTSSGLVYEGHWQKGQRHG--------IGSLRRKEL-DGRMERI----------YVGQWRENKRSGEGKQFYPDGSVYFGQWLADQRSGEGILWQADGGIYVGEWLRDKMHEKGLLFTATGNRYVGQFEGGCKSGSGVFYHASNGQRIQHGFWSKDI-CR 177
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Fly
Match: Als2 (gene:FBgn0037116 transcript:FBtr0078462) HSP 1 Score: 65.855 bits (159), Expect = 6.962e-11 Identity = 53/173 (30.64%), Postives = 73/173 (42.20%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVM-----ADGSFYEGEFQNGEICGKG----ERYWPKTGNVYRGEFHNGEMTGTGIMF-YGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDG 579
+ Y GE + EGFG V Y G ++ G+ HGHG + M + YEG F G G G RY +Y GE+ +G G++ +GD+Y G + N R G G GD +EG F + G G+ N Y G +G G+ MP G
Sbjct: 764 SVYCGELQHGIIEGFGKMVIPTTGL-YVGNFKGGRFHGHGVYEMHCKDSPESEVYEGNFCEGLFHGHGVMRNNRY------IYVGEYQANARSGYGVIEDLVSGDKYMGMFADNKRSGIGSCITNRGDYFEGSFSGDDLTGSGVAVFENDYYYEGELTLLGPNGRGEYYMPSG 929 HSP 2 Score: 60.8474 bits (146), Expect = 2.430e-9 Identity = 53/153 (34.64%), Postives = 69/153 (45.10%), Query Frame = 1
Query: 175 GEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKM-TMPDGSVYEGQFNYNLFHGEGT 630
G W+KG HG+ DGS Y GE Q+G I G G+ P TG +Y G F G G G+ E H +S E +VYEG F + HG G+MR N IY G + + G+G + + G Y G F N G G+
Sbjct: 745 GTWRKGVLHGNCYLEYPDGSVYCGELQHGIIEGFGKMVIPTTG-LYVGNFKGGRFHGHGVY------EMH---CKDSPE---------SEVYEGNFCEGLFHGHGVMR-NNRYIYVGEYQANARSGYGVIEDLVSGDKYMGMFADNKRSGIGS 877 HSP 3 Score: 54.299 bits (129), Expect = 2.611e-7 Identity = 34/88 (38.64%), Postives = 40/88 (45.45%), Query Frame = 1
Query: 385 GDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTM-----PDGSVYEGQFNYNLFHGEGTL 633
G W GN L Y +G VY GE I G G M + +Y G + G HGHG M P+ VYEG F LFHG G +
Sbjct: 745 GTWRKGVLHGNCYLEYPDGSVYCGELQHGIIEGFGKMVIPTTGLYVGNFKGGRFHGHGVYEMHCKDSPESEVYEGNFCEGLFHGHGVM 832
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0079861) HSP 1 Score: 50.8322 bits (120), Expect = 3.237e-6 Identity = 46/143 (32.17%), Postives = 66/143 (46.15%), Query Frame = 1
Query: 208 GRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNG-EMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMR--LMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEG 627
GRF DG Y G + G+ G G PK Y G ++ G E++G+ I + +G Y G W + R G G + +Y GE+ K G +R ++ + Y G W G + G G T DG Y+GQ+ HG G
Sbjct: 50 GRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYI--WPSGSHYEGQWQNGRRHGLG-VEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYG 189 HSP 2 Score: 50.447 bits (119), Expect = 4.151e-6 Identity = 41/138 (29.71%), Postives = 62/138 (44.93%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICG---KGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGN--GQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMT 567
Y G W +GK HGHG + G ++G + G G WP +G+ Y G++ NG G G+ G Y G+W + +G + + + YEG + + G G +G Y G W G +HG+G T
Sbjct: 60 YCGGWDEGKAHGHG---VCTGPKHQGAYAGAWNYGFEVSGSYIWP-SGSHYEGQWQNGRRHGLGVEQIGR-QIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRT 192
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Zebrafish
Match: rsph10b (radial spoke head 10 homolog B [Source:NCBI gene;Acc:767792]) HSP 1 Score: 115.546 bits (288), Expect = 1.187e-26 Identity = 73/207 (35.27%), Postives = 107/207 (51.69%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE--YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGKMT----------MPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWE 672
+ Y G + L G+G Y++ + KY+G+++ GHG + +GS YEGE G G G KT VYRG+++ G+ G G MFY Y G+W++N +EG G+ Y +G+VYEG++ + HGEG MR ++ YSG WI G + G G T P + Y G F + HG+G + G LY G W+
Sbjct: 107 HVYKGSFSHGLMHGYGEYIWSDGL-KYQGDFKVNVPMGHGTYTWLNGSTYEGEVHQGIRHGVGMYKCVKTLTVYRGQWYLGKRQGQGEMFYNQEATSWYKGEWVNNCKEGWGKRCYPSGNVYEGQWRNNVRHGEGTMRWIDLDQQYSGQWINGTQEGKGTHTWFRKRAPSSQYPRMNEYTGDFVQAMRHGQGQFLYASGALYCGQWK 312 HSP 2 Score: 98.5969 bits (244), Expect = 3.339e-21 Identity = 62/182 (34.07%), Postives = 93/182 (51.10%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFV--MADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE-YHGDWISNSREGNGQLT----------YANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFN 603
Y GE ++ +R G G+Y Y G+W GK+ G G S+Y+GE+ N G G+R +P +GNVY G++ N G G M + + D+ Y G WI+ ++EG G T Y + Y G+F + HG+G +G++Y G W KHG G+ +G VYEG+F+
Sbjct: 155 YEGEVHQGIRHGVGMYKCVKTLTVYRGQWYLGKRQGQGEMFYNQEATSWYKGEWVNNCKEGWGKRCYP-SGNVYEGQWRNNVRHGEGTMRWIDLDQQYSGQWINGTQEGKGTHTWFRKRAPSSQYPRMNEYTGDFVQAMRHGQGQFLYASGALYCGQWKYDKKHGQGRYIFENGRVYEGEFS 335 HSP 3 Score: 66.6254 bits (161), Expect = 4.765e-11 Identity = 47/142 (33.10%), Postives = 68/142 (47.89%), Query Frame = 1
Query: 79 KDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYW----------PKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYK 468
++ ++Y GE +EG+G Y + YEG+W+ +HG G R++ D Y G++ NG GKG W P+ N Y G+F G G Y +G Y G W + + G G+ + NG VYEGEF K
Sbjct: 198 QEATSWYKGEWVNNCKEGWGKRCYPSGNV-YEGQWRNNVRHGEGTMRWIDLDQQ-YSGQWINGTQEGKGTHTWFRKRAPSSQYPRM-NEYTGDFVQAMRHGQGQFLYASGALYCGQWKYDKKHGQGRYIFENGRVYEGEFSK 336
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Zebrafish
Match: rsph10b (radial spoke head 10 homolog B [Source:NCBI gene;Acc:767792]) HSP 1 Score: 115.546 bits (288), Expect = 1.311e-26 Identity = 73/207 (35.27%), Postives = 107/207 (51.69%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN--GDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGKMT----------MPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWE 672
+ Y G + L G+G Y++ + KY+G+++ GHG + +GS YEGE G G G KT VYRG+++ G+ G G MFY Y G+W++N +EG G+ Y +G+VYEG++ + HGEG MR ++ YSG WI G + G G T P + Y G F + HG+G + G LY G W+
Sbjct: 107 HVYKGSFSHGLMHGYGEYIWSDGL-KYQGDFKVNVPMGHGTYTWLNGSTYEGEVHQGIRHGVGMYKCVKTLTVYRGQWYLGKRQGQGEMFYNQEATSWYKGEWVNNCKEGWGKRCYPSGNVYEGQWRNNVRHGEGTMRWIDLDQQYSGQWINGTQEGKGTHTWFRKRAPSSQYPRMNEYTGDFVQAMRHGQGQFLYASGALYCGQWK 312 HSP 2 Score: 98.5969 bits (244), Expect = 3.490e-21 Identity = 62/182 (34.07%), Postives = 93/182 (51.10%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFV--MADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE-YHGDWISNSREGNGQLT----------YANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFN 603
Y GE ++ +R G G+Y Y G+W GK+ G G S+Y+GE+ N G G+R +P +GNVY G++ N G G M + + D+ Y G WI+ ++EG G T Y + Y G+F + HG+G +G++Y G W KHG G+ +G VYEG+F+
Sbjct: 155 YEGEVHQGIRHGVGMYKCVKTLTVYRGQWYLGKRQGQGEMFYNQEATSWYKGEWVNNCKEGWGKRCYP-SGNVYEGQWRNNVRHGEGTMRWIDLDQQYSGQWINGTQEGKGTHTWFRKRAPSSQYPRMNEYTGDFVQAMRHGQGQFLYASGALYCGQWKYDKKHGQGRYIFENGRVYEGEFS 335 HSP 3 Score: 66.6254 bits (161), Expect = 4.933e-11 Identity = 47/142 (33.10%), Postives = 68/142 (47.89%), Query Frame = 1
Query: 79 KDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYW----------PKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYK 468
++ ++Y GE +EG+G Y + YEG+W+ +HG G R++ D Y G++ NG GKG W P+ N Y G+F G G Y +G Y G W + + G G+ + NG VYEGEF K
Sbjct: 198 QEATSWYKGEWVNNCKEGWGKRCYPSGNV-YEGQWRNNVRHGEGTMRWIDLDQQ-YSGQWINGTQEGKGTHTWFRKRAPSSQYPRM-NEYTGDFVQAMRHGQGQFLYASGALYCGQWKYDKKHGQGRYIFENGRVYEGEFSK 336
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Zebrafish
Match: morn3 (MORN repeat containing 3 [Source:ZFIN;Acc:ZDB-GENE-050417-152]) HSP 1 Score: 96.2857 bits (238), Expect = 5.156e-22 Identity = 62/157 (39.49%), Postives = 87/157 (55.41%), Query Frame = 1
Query: 145 VYENKFFKYEGEWQKGKKHGHGRFVMAD-GSFYEGEFQNGEICGKG--ERYWPKTG---NVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD-GSVYEG 594
VY +Y GEW KKHG G+ V G Y+G+++ G+ G G R P+T VY G + N + G G FY Y G W + R G G++ Y NG++YEGE+ + K HGEG++ L NG+ + G W G K+GHG++ D G +YEG
Sbjct: 30 VYSVNGDQYTGEWMDNKKHGKGKQVWKRAGIVYDGDWRCGKRDGFGTLSRMDPETKEYTRVYVGSWRNDKKEGAGSYFYSASAFYEGQWSGDERSGWGRMQYENGELYEGEWLRDKHHGEGLILLANGNRFVGTWSDGKKNGHGQLFFLDRGQLYEG 186 HSP 2 Score: 77.7962 bits (190), Expect = 1.230e-15 Identity = 51/174 (29.31%), Postives = 88/174 (50.57%), Query Frame = 1
Query: 184 QKGKKHG-HGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE------YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLWEQNL 681
+K +K+G H +G Y GE+ + + GKG++ W + G VY G++ G+ G G + + + Y G W ++ +EG G Y+ YEG++ + G G M+ NG +Y G W+ HG G + + +G+ + G ++ +G G LF + G LY G W ++
Sbjct: 19 RKAQKYGLHHTVYSVNGDQYTGEWMDNKKHGKGKQVWKRAGIVYDGDWRCGKRDGFGTLSRMDPETKEYTRVYVGSWRNDKKEGAGSYFYSASAFYEGQWSGDERSGWGRMQYENGELYEGEWLRDKHHGEGLILLANGNRFVGTWSDGKKNGHGQLFFLDRGQLYEGFWVDDV 192 HSP 3 Score: 53.5286 bits (127), Expect = 1.983e-7 Identity = 45/177 (25.42%), Postives = 68/177 (38.42%), Query Frame = 1
Query: 73 EIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWI-----CGNKHGHGKMTMPDGSVY 588
E K+ Y+G +EG G Y Y F YEG+W ++ G GR +G YEGE+ + H+GE G++ NG+ + G W + G+GQL + L G +Y G+W+ CG+ G+ T +VY
Sbjct: 83 ETKEYTRVYVGSWRNDKKEGAGSYFYSASAF-YEGQWSGDERSGWGRMQYENGELYEGEWLRDK--------------------HHGE----GLILLANGNRFVGTWSDGKKNGHGQLFF----------------------LDRGQLYEGFWVDDVAKCGSISDFGRETAVRPTVY 212
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Zebrafish
Match: morn3 (MORN repeat containing 3 [Source:ZFIN;Acc:ZDB-GENE-050417-152]) HSP 1 Score: 95.9005 bits (237), Expect = 6.619e-22 Identity = 62/157 (39.49%), Postives = 87/157 (55.41%), Query Frame = 1
Query: 145 VYENKFFKYEGEWQKGKKHGHGRFVMAD-GSFYEGEFQNGEICGKG--ERYWPKTG---NVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD-GSVYEG 594
VY +Y GEW KKHG G+ V G Y+G+++ G+ G G R P+T VY G + N + G G FY Y G W + R G G++ Y NG++YEGE+ + K HGEG++ L NG+ + G W G K+GHG++ D G +YEG
Sbjct: 30 VYSVNGDQYTGEWMDNKKHGKGKQVWKRAGIVYDGDWRCGKRDGFGTLSRMDPETKEYTRVYVGTWRNDKKEGAGSYFYSASAFYEGQWSGDERSGWGRMQYENGELYEGEWLRDKHHGEGLILLANGNRFVGTWSDGKKNGHGQLFFLDRGQLYEG 186 HSP 2 Score: 77.411 bits (189), Expect = 1.663e-15 Identity = 51/174 (29.31%), Postives = 88/174 (50.57%), Query Frame = 1
Query: 184 QKGKKHG-HGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE------YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLWEQNL 681
+K +K+G H +G Y GE+ + + GKG++ W + G VY G++ G+ G G + + + Y G W ++ +EG G Y+ YEG++ + G G M+ NG +Y G W+ HG G + + +G+ + G ++ +G G LF + G LY G W ++
Sbjct: 19 RKAQKYGLHHTVYSVNGDQYTGEWMDNKKHGKGKQVWKRAGIVYDGDWRCGKRDGFGTLSRMDPETKEYTRVYVGTWRNDKKEGAGSYFYSASAFYEGQWSGDERSGWGRMQYENGELYEGEWLRDKHHGEGLILLANGNRFVGTWSDGKKNGHGQLFFLDRGQLYEGFWVDDV 192 HSP 3 Score: 53.1434 bits (126), Expect = 2.517e-7 Identity = 45/177 (25.42%), Postives = 68/177 (38.42%), Query Frame = 1
Query: 73 EIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWI-----CGNKHGHGKMTMPDGSVY 588
E K+ Y+G +EG G Y Y F YEG+W ++ G GR +G YEGE+ + H+GE G++ NG+ + G W + G+GQL + L G +Y G+W+ CG+ G+ T +VY
Sbjct: 83 ETKEYTRVYVGTWRNDKKEGAGSYFYSASAF-YEGQWSGDERSGWGRMQYENGELYEGEWLRDK--------------------HHGE----GLILLANGNRFVGTWSDGKKNGHGQLFF----------------------LDRGQLYEGFWVDDVAKCGSISDFGRETAVRPTVY 212
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Zebrafish
Match: als2b (alsin Rho guanine nucleotide exchange factor ALS2 b [Source:ZFIN;Acc:ZDB-GENE-080929-1]) HSP 1 Score: 91.2781 bits (225), Expect = 1.045e-18 Identity = 63/202 (31.19%), Postives = 95/202 (47.03%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFK----YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPK----TGNVYRGEFHNGEMTGTGIM-FYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICG-NKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGL 666
Y G +GFG YV NK Y+G+W+ GK HG G F A G YEG FQ+ G G K + +V+ G++ + +G G+ G++Y G W+ + R+GNG + G YEG F +K+ G G++ + + + G ++ +G G +TMP+G EG F CG+ TGL
Sbjct: 1100 RMYTGTFKNGFEDGFGDYVVSNKTLNSCDHYQGQWKDGKMHGFGTFRYASGEVYEGSFQDNMRHGHGMLRSGKLNSTSPSVFIGQWQYDKKSGYGVFDDITRGEKYMGMWLDDQRQGNGVVVTQFGLYYEGAFSNNKMMGTGVLLSEDDTTFEGEFLEDWTLNGKGVLTMPNGDYIEGSF--------------CGVWGTGL 1287 HSP 2 Score: 82.0333 bits (201), Expect = 8.805e-16 Identity = 57/170 (33.53%), Postives = 81/170 (47.65%), Query Frame = 1
Query: 157 KFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWP-KTGNV---YRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREG-----NGQLTYANGDVYEGEFYKHKIHGEGIM-RLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLF 636
K KY+G W GK HG G DG Y G F+NG G G+ KT N Y+G++ +G+M G G Y +G+ Y G + N R G +G+L + V+ G++ K G G+ + G Y G W+ + G+G + G YEG F+ N G G L
Sbjct: 1075 KDAKYDGRWVSGKPHGRGVVKWPDGRMYTGTFKNGFEDGFGDYVVSNKTLNSCDHYQGQWKDGKMHGFGTFRYASGEVYEGSFQDNMRHGHGMLRSGKLNSTSPSVFIGQWQYDKKSGYGVFDDITRGEKYMGMWLDDQRQGNGVVVTQFGLYYEGAFSNNKMMGTGVLL 1244
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Xenopus
Match: igf2 (insulin like growth factor 2 [Source:Xenbase;Acc:XB-GENE-482586]) HSP 1 Score: 286.189 bits (731), Expect = 7.372e-90 Identity = 164/479 (34.24%), Postives = 255/479 (53.24%), Query Frame = 1
Query: 88 NNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLT-TDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSL--FELIEQIDSKPVETTY-YPVLLVPLTDKPPQWVQSLENASHNKIRLP-------------HLFESDESNSQPPESTETDLT---------DAPLCNDLCLDPVIQETKNGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASVSA-----TSIKQNK-DQSLSEKNIKHK------ELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
+ +Y G K LR+G+G+YVYEN FF+YEG+W+ GKKHGHG+ + DGS+YEGEF +GEI G G RYW +GN Y GEF GE+ G G+M Y +G Y G+++ +EG+G L G Y G F+ +K +G G M+ MNG Y G WI + GHG + DGS+YEGQ+ ++F+G+G + H G++Y GLW P KM + DI++ QG + + + T+ GE V E+GR L+++AG+KY N + +L ELIE ++ KP ++ + Y + PLT Q+ + H K +P HL E+ S S E L + +++C P + G F ++ + P A C ++D + +SA ++ Q K + S SE +IK + +L D + GEY++I++D+T PF+ L ++ ++++
Sbjct: 11 SRYYTGGIKKQLRDGYGLYVYENSFFRYEGQWKSGKKHGHGKLLFKDGSYYEGEFADGEITGNGLRYWSSSGNKYSGEFQTGEIHGHGVMQYKDGGRYEGEFVFGIKEGHGLLMDKEGQTYSGAFHNNKKYGVGQMKFMNGDHYEGDWILDQRQGHGVLQCTDGSIYEGQWRNDVFNGQGIMIHCSGVIYDGLWINGHPAVAAKKMVIIGEDIINFIQGSRSTVHVQIQTEEGETVKNENGRVLKISAGIKYSQPNRSQTLSFLELIEDLEEKPFQSPFGYECINYPLT-------QTASRSQHQKDTIPFNSQSGSAPFGGSHLSENSISEHGFVASQEAGLALNSSGEYPEISGTTDEMCFLPSNVRVEAGCAIFSDIMLGPPS-AKFHCDETDKNKGKKPNGKISAEKTEKMTVSQEKIEDSRSETSIKDRKVKKDNQLQDSNIVRPGEYIIIVKDVTSPPFLGYTLPPVFKRVRL 481
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Xenopus
Match: igf2 (insulin like growth factor 2 [Source:Xenbase;Acc:XB-GENE-482586]) HSP 1 Score: 249.595 bits (636), Expect = 1.872e-77 Identity = 123/281 (43.77%), Postives = 176/281 (62.63%), Query Frame = 1
Query: 88 NNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLT-TDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSL--FELIEQIDSKPVETTYYP 921
+ +Y G K LR+G+G+YVYEN FF+YEG+W+ GKKHGHG+ + DGS+YEGEF +GEI G G RYW +GN Y GEF GE+ G G+M Y +G Y G+++ +EG+G L G Y G F+ +K +G G M+ MNG Y G WI + GHG + DGS+YEGQ+ ++F+G+G + H G++Y GLW P KM + DI++ QG + + + T+ GE V E+GR L+++AG+KY N + +L ELIE ++ KP + YP
Sbjct: 5 SRYYTGGIKKQLRDGYGLYVYENSFFRYEGQWKSGKKHGHGKLLFKDGSYYEGEFADGEITGNGLRYWSSSGNKYSGEFQTGEIHGHGVMQYKDGGRYEGEFVFGIKEGHGLLMDKEGQTYSGAFHNNKKYGVGQMKFMNGDHYEGDWILDQRQGHGVLQCTDGSIYEGQWRNDVFNGQGIMIHCSGVIYDGLWINGHPAVAAKKMVIIGEDIINFIQGSRSTVHVQIQTEEGETVKNENGRVLKISAGIKYSQPNRSQTLSFLELIEDLEEKPFQK--YP 283
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Xenopus
Match: igf2 (insulin like growth factor 2 [Source:Xenbase;Acc:XB-GENE-482586]) HSP 1 Score: 229.95 bits (585), Expect = 1.926e-70 Identity = 118/294 (40.14%), Postives = 173/294 (58.84%), Query Frame = 1
Query: 133 FGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLT-TDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSLFELIEQIDSKPVETTYYPVLLVPLTDKPPQWVQSLENASHNKIRLPHL 1011
+G+YVYEN FF+YEG+W+ GKKHGHG+ + DGS+YEGEF +GEI G G RYW +GN Y GEF GE+ G G+M Y +G Y G+++ +EG+G L G Y G F+ +K +G G M+ MNG Y G WI + GHG + DGS+YEGQ+ ++F+G+G + H G++Y GLW P KM + DI++ QG + + + T+ GE V E+GR L+++AG+KY N + +L E I I K V + + +P K + + + N+ P +
Sbjct: 27 YGLYVYENSFFRYEGQWKSGKKHGHGKLLFKDGSYYEGEFADGEITGNGLRYWSSSGNKYSGEFQTGEIHGHGVMQYKDGGRYEGEFVFGIKEGHGLLMDKEGQTYSGAFHNNKKYGVGQMKFMNGDHYEGDWILDQRQGHGVLQCTDGSIYEGQWRNDVFNGQGIMIHCSGVIYDGLWINGHPAVAAKKMVIIGEDIINFIQGSRSTVHVQIQTEEGETVKNENGRVLKISAGIKYSQPNRSQTLREYI--IIVKDVTSPPFLGYTLPPVFKRVRLLHEKSKSKTNQKEAPKI 318
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Xenopus
Match: igf2 (insulin like growth factor 2 [Source:Xenbase;Acc:XB-GENE-482586]) HSP 1 Score: 201.83 bits (512), Expect = 5.090e-61 Identity = 96/213 (45.07%), Postives = 135/213 (63.38%), Query Frame = 1
Query: 88 NNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDIL 726
+ +Y G K LR+G+G+YVYEN FF+YEG+W+ GKKHGHG+ + DGS+YEGEF +GEI G G RYW +GN Y GEF GE+ G G+M Y +G Y G+++ +EG+G L G Y G F+ +K +G G M+ MNG Y G WI + GHG + DGS+YEGQ+ ++F+G+G + H G++Y GLW P + ++ L
Sbjct: 5 SRYYTGGIKKQLRDGYGLYVYENSFFRYEGQWKSGKKHGHGKLLFKDGSYYEGEFADGEITGNGLRYWSSSGNKYSGEFQTGEIHGHGVMQYKDGGRYEGEFVFGIKEGHGLLMDKEGQTYSGAFHNNKKYGVGQMKFMNGDHYEGDWILDQRQGHGVLQCTDGSIYEGQWRNDVFNGQGIMIHCSGVIYDGLWINGHPAGLCAVIRKVVASL 217
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Xenopus
Match: igf2 (insulin like growth factor 2 [Source:Xenbase;Acc:XB-GENE-482586]) HSP 1 Score: 198.364 bits (503), Expect = 8.605e-60 Identity = 96/205 (46.83%), Postives = 133/205 (64.88%), Query Frame = 1
Query: 88 NNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTK 702
+ +Y G K LR+G+G+YVYEN FF+YEG+W+ GKKHGHG+ + DGS+YEGEF +GEI G G RYW +GN Y GEF GE+ G G+M Y +G Y G+++ +EG+G L G Y G F+ +K +G G M+ MNG Y G WI + GHG + DGS+YEGQ+ ++F+G+G + H G++Y GLW P + K
Sbjct: 5 SRYYTGGIKKQLRDGYGLYVYENSFFRYEGQWKSGKKHGHGKLLFKDGSYYEGEFADGEITGNGLRYWSSSGNKYSGEFQTGEIHGHGVMQYKDGGRYEGEFVFGIKEGHGLLMDKEGQTYSGAFHNNKKYGVGQMKFMNGDHYEGDWILDQRQGHGVLQCTDGSIYEGQWRNDVFNGQGIMIHCSGVIYDGLWINGHPHDLWPK 209
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Mouse
Match: Morn1 (MORN repeat containing 1 [Source:MGI Symbol;Acc:MGI:1924116]) HSP 1 Score: 222.631 bits (566), Expect = 5.138e-66 Identity = 149/444 (33.56%), Postives = 229/444 (51.58%), Query Frame = 1
Query: 124 REGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMK-LTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKY--QPVNDNNSLFELIEQIDSKPVETTY------YPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTETDLTDAPLCNDLCLDPVIQETKNGSVDFINLFI------QQPKLAAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
R G+GVYVY N FF+YEGEW+ GKKHGHG+ + DGS+YEGEF +GEI G+G ++W +GN Y G+F GE G G+M Y G Y G+ REG G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y+GQ++ ++F G G+L H G+ Y G++ P + K+ L ++L+ QG F +S+ L D+GE+ ESGR L+++AGV+Y P S F++ E P++T + YP L VP++ P+ ++E+A + + L + D + + P Q+ +G +F+++ + QP L L+ +S Q + + + E + LGEYVL++ D+T PF+ +RL T + ++I
Sbjct: 24 RNGYGVYVYPNSFFRYEGEWKGGKKHGHGKLLFKDGSYYEGEFVDGEITGEGCQHWAWSGNTYSGQFVLGEPQGHGVMKYKAGGRYEGELSQGLREGQGFLEDQDGQVYQGSFHDNKRHGRGQMIFKNGDKYEGDWVRDQRQGHGVLCCADGSTYKGQWHSDVFSGLGSLVHCSGVTYCGMFINGHPAEQAKKIVILGPEVLEVVQGSPFTLSVQLQQDDGEVAKSESGRVLKISAGVRYVQLPEYSEVSFFKMDEDYMETPIQTPFGFQCISYP-LSVPMSWG-PEPGSTVESARADLL----LSKRDSEPVLDSGAFHGQGDTLSILPARRHKPCCQQVDHGCAEFVDILLGAPPPGMQPYLFLPGTLEKTLGRPKGGPSSPEVLPTAQEPLKGTNRPDGTTVEPPTAAY--LGEYVLMVCDVTSPPFLGHRLPTTFKHLRI 459
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Mouse
Match: Morn1 (MORN repeat containing 1 [Source:MGI Symbol;Acc:MGI:1924116]) HSP 1 Score: 175.252 bits (443), Expect = 1.009e-50 Identity = 99/224 (44.20%), Postives = 138/224 (61.61%), Query Frame = 1
Query: 124 REGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMK-LTTDILDCFQGHTFQISLTLITDNGEIV 792
R G+GVYVY N FF+YEGEW+ GKKHGHG+ + DGS+YEGEF +GEI G+G ++W +GN Y G+F GE G G+M Y G Y G+ REG G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y+GQ++ ++F G G+L H G+ Y G++ P + K+ L ++L+ QG F +S+ L D+GE+
Sbjct: 24 RNGYGVYVYPNSFFRYEGEWKGGKKHGHGKLLFKDGSYYEGEFVDGEITGEGCQHWAWSGNTYSGQFVLGEPQGHGVMKYKAGGRYEGELSQGLREGQGFLEDQDGQVYQGSFHDNKRHGRGQMIFKNGDKYEGDWVRDQRQGHGVLCCADGSTYKGQWHSDVFSGLGSLVHCSGVTYCGMFINGHPAEQAKKIVILGPEVLEVVQGSPFTLSVQLQQDDGEVA 247
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Mouse
Match: Morn1 (MORN repeat containing 1 [Source:MGI Symbol;Acc:MGI:1924116]) HSP 1 Score: 135.576 bits (340), Expect = 1.889e-36 Identity = 80/168 (47.62%), Postives = 103/168 (61.31%), Query Frame = 1
Query: 124 REGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVY----EGQFNYNLF 615
R G+GVYVY N FF+YEGEW+ GKKHGHG+ + DGS+YEGEF +GEI G+G ++W +GN Y G+F GE G G+M Y G Y G+ REG G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y E F Y++
Sbjct: 24 RNGYGVYVYPNSFFRYEGEWKGGKKHGHGKLLFKDGSYYEGEFVDGEITGEGCQHWAWSGNTYSGQFVLGEPQGHGVMKYKAGGRYEGELSQGLREGQGFLEDQDGQVYQGSFHDNKRHGRGQMIFKNGDKYEGDWVRDQRQGHGVLCCADGSTYKSAPEADFPYSVL 191
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Mouse
Match: Morn3 (MORN repeat containing 3 [Source:MGI Symbol;Acc:MGI:1922140]) HSP 1 Score: 98.5969 bits (244), Expect = 6.498e-23 Identity = 62/178 (34.83%), Postives = 93/178 (52.25%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTG---NVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD-GSVYEGQFNYNL 612
+ Y+GE L+ G G V++ YEG+W+ GK+ G+G D P+TG VY G + + +G GI F+G + Y G+W +N R G G++ Y NGD+YEG++ K GEG++RL NG+ Y G W G K+GHG+ D G ++EG + N+
Sbjct: 36 DHYVGEWKGNLKHGKGTQVWKKSGAVYEGDWKFGKRDGYGSLSHPD---------------------PETGKLRRVYSGWWKGDKKSGYGIQFFGPKEYYEGEWCNNQRSGWGRMYYNNGDIYEGQWQNDKPEGEGMLRLKNGNRYEGIWERGMKNGHGRFFHLDHGQLFEGYWVDNV 192 HSP 2 Score: 75.0998 bits (183), Expect = 9.024e-15 Identity = 62/213 (29.11%), Postives = 99/213 (46.48%), Query Frame = 1
Query: 184 QKGKKHGHGRFVMA-DGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE------YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHE 798
+K +K+G V A +G Y GE++ GKG + W K+G VY G++ G+ G G + + + + Y G W + + G G + + YEGE+ ++ G G M NG IY G W G G + + +G+ YEG + + +G G FH+ G L+ G W N+ K T + D + + F I I D ++ E
Sbjct: 19 RKAQKNGLRHQVFAVNGDHYVGEWKGNLKHGKGTQVWKKSGAVYEGDWKFGKRDGYGSLSHPDPETGKLRRVYSGWWKGDKKSGYGIQFFGPKEYYEGEWCNNQRSGWGRMYYNNGDIYEGQWQNDKPEGEGMLRLKNGNRYEGIWERGMKNGHGRFFHLDHGQLFEGYWVDNV-AKCGTMIDFGRD--EAPEPTQFPIPKVEILDPDGVLKE 228
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Mouse
Match: Morn1 (MORN repeat containing 1 [Source:MGI Symbol;Acc:MGI:1924116]) HSP 1 Score: 89.7373 bits (221), Expect = 5.584e-21 Identity = 52/100 (52.00%), Postives = 69/100 (69.00%), Query Frame = 1
Query: 124 REGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWP---------KTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWI 396
R G+GVYVY N FF+YEGEW+ GKKHGHG+ + DGS+YEGEF +GEI G+G ++W + G VY+G FH+ + G G M + NGD+Y GDW+
Sbjct: 24 RNGYGVYVYPNSFFRYEGEWKGGKKHGHGKLLFKDGSYYEGEFVDGEITGEGCQHWAWSGQGFLEDQDGQVYQGSFHDNKRHGRGQMIFKNGDKYEGDWV 123
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. UniProt/SwissProt
Match: sp|Q5T089|MORN1_HUMAN (MORN repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=MORN1 PE=2 SV=2) HSP 1 Score: 234.572 bits (597), Expect = 1.906e-69 Identity = 141/444 (31.76%), Postives = 225/444 (50.68%), Query Frame = 1
Query: 130 GFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMK-LTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSL-FELIEQIDSKPVETTYYPVLLVPLTDKPPQW----VQSLENASHNKIRLPHL-FESDESNSQPPESTETDLTD---APLCNDLCLDPVIQETKNGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASV-------SATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
G+GVYVY N FF+YEGEW+ G+KHGHG+ + DGS+YEG F +GEI G+G R+W +G+ + G+F GE G G+M Y G Y G+ REG+G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y+GQ++ ++F G G++ H G+ Y GLW P + T++ L ++++ QG F +++ L+ D+GEI ESGR L+++AGV+Y ++ + + F +++ + + + T + +P P ++ + + + LP E E T L AP C C Q + G +F ++ + P L DS + S + + ++ S E ++ LGEYVL+I D+T PF+ RL + +++
Sbjct: 26 GYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVNVQLLQDHGEIAKSESGRVLQISAGVRYVQLSAYSEVNFFKVDRDNQETLIQTPFGFECIPYPVSSPAAGVPGPRAAKGGAEADVPLPRGDLELHLGALHGQEDTPGGLLARGHAPHCPGAC-----QRVEQGCAEFTDVLLGPPPPGYHPFLFLDSLHKKAGGRSRGGLHPRGTPPTAQEPPGGSRPEGRATEEQA---AAAHLGEYVLMIRDVTTPPFLGRRLPPAFKHLRV 461
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. UniProt/SwissProt
Match: sp|Q641X6|MORN1_RAT (MORN repeat-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Morn1 PE=1 SV=1) HSP 1 Score: 225.328 bits (573), Expect = 4.270e-66 Identity = 154/446 (34.53%), Postives = 231/446 (51.79%), Query Frame = 1
Query: 124 REGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKM-KLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKY--QPVNDNNSLFELIEQIDSKPVETTY-YPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTET------DLTDAPL-CNDLCLDPVIQETKNGSVDFINLFI------QQPKLAAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
R G+GVYVY N FF+YEGEW+ GKKHGHG+ + DGS+YEGEF NGEI G+G ++W +GN Y G+F GE G GIM Y G Y G+ REG G L +G VY+G F+ +K HG G M NG Y G W+ + GHG + DGS Y+GQ++ ++F G G+L H G+ Y G++ P K+ L ++L+ QG F +S+ L D+GE+ ESGR L+++AGV+Y P S F++ + P++T + + + PL+ W LE S + L S + +S+P +E L+ P ++ C Q G +F+++ + QP L S L+ + + S Q + + + E + LGEYVL++ D+T PF+ +RL T + ++I
Sbjct: 24 RNGYGVYVYPNSFFRYEGEWKGGKKHGHGKLLFKDGSYYEGEFVNGEITGEGYQHWAWSGNTYSGQFVLGEPQGHGIMKYKAGGHYEGELSQGLREGQGFLEDQDGQVYQGSFHDNKRHGRGQMVFKNGDKYEGDWVRDQRQGHGVLFCADGSTYKGQWHNDVFSGLGSLVHCSGVTYCGMFINGHPAAQAKKIVVLGPELLEVVQGSPFTLSVQLQQDDGEVAKSESGRVLKISAGVRYVQLPEYSEVSFFKMDDAHMETPIQTPFGFQCIPYPLSVS-TSW--GLEPGSTVESARADLLLS-KKDSEPVLDSEAFHGKGDTLSILPARRHEPCCSAAYQRVDQGCAEFVDIHLGAPPPGMQPYLFLPSMLEKAGNRPKGDRSPPEVLSTAQEPLRGTNRSDGTTAEPSTAAY--LGEYVLMVCDVTSPPFLGHRLPTTFKHLRI 463
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. UniProt/SwissProt
Match: sp|Q8L796|PI5K2_ARATH (Phosphatidylinositol 4-phosphate 5-kinase 2 OS=Arabidopsis thaliana OX=3702 GN=PIP5K2 PE=1 SV=2) HSP 1 Score: 122.479 bits (306), Expect = 4.926e-28 Identity = 64/170 (37.65%), Postives = 96/170 (56.47%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
Y G + G +G G+++ DG YEGE++ G+ GKG+ WP +G Y GEF +G M G+G +GD Y G W+++ ++G+GQ YANGD YEG + ++ G G MNG+ Y+G W G G G + P+G+ YEGQ+ + G G G + G W ++
Sbjct: 82 YMGTFSGGFPNGSGKYLWKDGCMYEGEWKRGKASGKGKFSWP-SGATYEGEFKSGRMEGSGTFVGVDGDTYRGSWVADRKQGHGQKRYANGDYYEGTWRRNLQDGRGRYVWMNGNQYTGEWRNGVICGKGVLAWPNGNRYEGQWENGVPKGSGVFTWADGSSWIGSWNES 250 HSP 2 Score: 87.4261 bits (215), Expect = 1.025e-16 Identity = 43/129 (33.33%), Postives = 63/129 (48.84%), Query Frame = 1
Query: 301 GNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPC 687
G++Y G F G G+G + +G Y G+W G G+ ++ +G YEGEF ++ G G ++G Y G W+ K GHG+ +G YEG + NL G G + G YTG W + C
Sbjct: 79 GDLYMGTFSGGFPNGSGKYLWKDGCMYEGEWKRGKASGKGKFSWPSGATYEGEFKSGRMEGSGTFVGVDGDTYRGSWVADRKQGHGQKRYANGDYYEGTWRRNLQDGRGRYVWMNGNQYTGEWRNGVIC 207 HSP 3 Score: 71.633 bits (174), Expect = 9.045e-12 Identity = 37/94 (39.36%), Postives = 56/94 (59.57%), Query Frame = 1
Query: 124 REGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNS 405
++G G Y N + YEG W++ + G GR+V +G+ Y GE++NG ICGKG WP GN Y G++ NG G+G+ + +G + G W +S
Sbjct: 160 KQGHGQKRYANGDY-YEGTWRRNLQDGRGRYVWMNGNQYTGEWRNGVICGKGVLAWP-NGNRYEGQWENGVPKGSGVFTWADGSSWIGSWNESS 251
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. UniProt/SwissProt
Match: sp|Q9SFB8|PI5K6_ARATH (Phosphatidylinositol 4-phosphate 5-kinase 6 OS=Arabidopsis thaliana OX=3702 GN=PIP5K6 PE=2 SV=1) HSP 1 Score: 119.783 bits (299), Expect = 3.743e-27 Identity = 62/170 (36.47%), Postives = 89/170 (52.35%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
Y G+W+ HGHG+++ DG Y G++ G+ GKG WP +G Y G+F NG M G G +GD Y G W+ N R G G +Y NGD Y+GE+ + G G + N + Y G W G +G+G M +G+ Y+G + G GT G Y G+W ++
Sbjct: 32 YTGQWRDNLPHGHGKYLWTDGCMYVGDWHRGKTMGKGRFSWP-SGATYEGDFKNGYMDGKGTYIDSSGDLYRGSWVMNLRHGQGTKSYVNGDCYDGEWRRGLQDGHGRYQWKNENHYIGQWKNGLMNGNGTMIWSNGNRYDGSWEDGAPKGNGTFRWSDGSFYVGVWSKD 200 HSP 2 Score: 102.449 bits (254), Expect = 1.394e-21 Identity = 63/182 (34.62%), Postives = 95/182 (52.20%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLF 636
+FY G+ L G G Y++ + Y G+W +GK G GRF G+ YEG+F+NG + GKG Y +G++YRG + G G Y NGD Y G+W ++G+G+ + N + Y G++ ++G G M NG+ Y G W G G+G DGS Y G ++ + GT +
Sbjct: 30 DFYTGQWRDNLPHGHGKYLWTDGCM-YVGDWHRGKTMGKGRFSWPSGATYEGDFKNGYMDGKGT-YIDSSGDLYRGSWVMNLRHGQGTKSYVNGDCYDGEWRRGLQDGHGRYQWKNENHYIGQWKNGLMNGNGTMIWSNGNRYDGSWEDGAPKGNGTFRWSDGSFYVGVWSKDPKEQNGTYY 209 HSP 3 Score: 59.6918 bits (143), Expect = 4.796e-8 Identity = 34/98 (34.69%), Postives = 45/98 (45.92%), Query Frame = 1
Query: 436 NGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILD 729
+GD Y G++ + HG G +G +Y G W G G G+ + P G+ YEG F G+GT G LY G W NL TK + D D
Sbjct: 28 SGDFYTGQWRDNLPHGHGKYLWTDGCMYVGDWHRGKTMGKGRFSWPSGATYEGDFKNGYMDGKGTYIDSSGDLYRGSWVMNLRHGQGTKSYVNGDCYD 125
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. UniProt/SwissProt
Match: sp|Q56YP2|PI5K1_ARATH (Phosphatidylinositol 4-phosphate 5-kinase 1 OS=Arabidopsis thaliana OX=3702 GN=PIP5K1 PE=1 SV=1) HSP 1 Score: 116.316 bits (290), Expect = 4.892e-26 Identity = 62/170 (36.47%), Postives = 91/170 (53.53%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
Y G + G HG G+++ DG YEG+++ G+ GKG+ WP +G Y GEF +G M G G +GD Y G W+++ + G+GQ YANGD YEG + ++ G G NG+ Y+G W G G G + P+G+ YEG + + G G G G W ++
Sbjct: 81 YIGSFSGGFPHGSGKYLWKDGCMYEGDWKRGKASGKGKFSWP-SGATYEGEFKSGRMEGFGTFTGADGDTYRGTWVADRKHGHGQKRYANGDFYEGTWRRNLQDGRGRYVWRNGNQYTGEWRSGVISGKGLLVWPNGNRYEGLWENGIPKGNGVFTWSDGSSCVGAWNES 249 HSP 2 Score: 85.1149 bits (209), Expect = 5.331e-16 Identity = 44/127 (34.65%), Postives = 61/127 (48.03%), Query Frame = 1
Query: 301 GNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNL 681
G++Y G F G G+G + +G Y GDW G G+ ++ +G YEGEF ++ G G +G Y G W+ KHGHG+ +G YEG + NL G G G YTG W +
Sbjct: 78 GDLYIGSFSGGFPHGSGKYLWKDGCMYEGDWKRGKASGKGKFSWPSGATYEGEFKSGRMEGFGTFTGADGDTYRGTWVADRKHGHGQKRYANGDFYEGTWRRNLQDGRGRYVWRNGNQYTGEWRSGV 204 HSP 3 Score: 75.8702 bits (185), Expect = 3.999e-13 Identity = 49/150 (32.67%), Postives = 75/150 (50.00%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNK 546
Y GE EGFG + + Y G W +KHGHG+ A+G FYEG ++ G+G W + GN Y GE+ +G ++G G++ + NG+ Y G W + +GNG T+++G G + + IMR + I GN+
Sbjct: 127 YEGEFKSGRMEGFGTFTGADGD-TYRGTWVADRKHGHGQKRYANGDFYEGTWRRNLQDGRGRYVW-RNGNQYTGEWRSGVISGKGLLVWPNGNRYEGLWENGIPKGNGVFTWSDGSSCVGAW-----NESNIMRSFFNGVEKNDLIVGNR 269
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. TrEMBL
Match: A0A1S3IRS7 (MORN repeat-containing protein 1-like OS=Lingula unguis OX=7574 GN=LOC106166676 PE=4 SV=1) HSP 1 Score: 292.738 bits (748), Expect = 2.161e-89 Identity = 169/466 (36.27%), Postives = 252/466 (54.08%), Query Frame = 1
Query: 130 GFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTT----DILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNN----SLFELIEQIDSKPVETTY-YPVLLVPLTDKPPQWVQSLENA----------SHNKIRL----PHLFESD-ESNSQPPESTETDLTDAP---LCNDLCLDPVIQE----------------TKNGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASVSATSIKQNKDQS-LSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLY 1395
GFGVY YENKFF+YEG+W++GKKHGHG+ VMADGS+YEG F+NGEI G G RYW TGN YRG+FH GE+ G G+M Y +G Y GDW N R+G G + + G+VY+G F++HK HGEG M +NG +Y G W+ + GHG++ D S+Y+GQF +LF+GEGT++H G +Y GLW P ++ TK+ L + ++ QG TF + + TD GE+V E+ GR L++ AGV++QP +N S+ E +E+++ V T + + V P+T++ V+ +E+A + N I P E D E + + E T + P DL + + E T+ G+ + NL++ L D A+ ++ A S + D S K+ + + G+YV+ + D+T P+ + LE Y
Sbjct: 3 GFGVYNYENKFFRYEGQWREGKKHGHGKLVMADGSYYEGSFENGEIEGHGFRYWSSTGNTYRGQFHLGELHGQGVMNYSDGAVYKGDWFRNKRQGYGSIADSMGNVYQGYFHEHKKHGEGTMTYVNGDVYEGDWVMDKRQGHGQVKFADTSIYDGQFRNDLFNGEGTMYHCSGFVYEGLWINGEPAQLATKIVLVGTEEGNTIEITQGETFALQIECRTDEGEVV-EDQGRELQVIAGVRFQPPKENTPSGTSILETLEEMEEATVPTPFGFDVASYPITEQEASLVKDMESALSLQKSNTALTENTINEQDEDPEAGERDKEVDGEAGEGGSTHVQSRPESIAPEDLGANEEVSEEALEGSPEPPRITNVKTEKGTAKWDNLYLPPAPPGYRPFLVLDGAT--VDGAKKSKSRASSRGDGSGPGTKSKSRMSVTPGDLVRPGDYVIAVHDVTMPPWQDKPLEPAY 465
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. TrEMBL
Match: A0A1W5BI91 (MORN repeat-containing protein 1-like isoform X2 OS=Ciona intestinalis OX=7719 GN=LOC100176954 PE=4 SV=1) HSP 1 Score: 291.582 bits (745), Expect = 9.575e-89 Identity = 169/487 (34.70%), Postives = 265/487 (54.41%), Query Frame = 1
Query: 64 LKMEIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPC----KIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVND--NNSLFELIEQIDSKPVETTY-YPVLLVPL------TDKPPQWVQSLENASHNKIRL-------------PHLFE-----------SDESNSQPPESTETDLTDAPLCNDLCLDPVIQETK-NGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
+ + I ++ N+Y+GETN LREG+GVY Y NKFF+YEGEW KGKKHGHG+ +M DGS+YEGEF++GEI G G R W +TG+ Y GEF GE+ G G+M Y +G +Y G++ +N R G G LT +G+ YEG +YK+K HG+G+ NG Y G W+ G +HGHG++ DGS+YEGQ+ N+F+GEG++ H G+ Y GLW P +I ++ ++ QG F + ++ N E V GR R+TAG +Y P + N S+ ELIE ++ KP+ T + Y VL PL +++ + +++ S R+ PH E SD + Q ++ D + + P Q + +GSV+F +L++ L + + + +A++ + ++S K K K +E+ K GEY++I+ ++T PF+ + L + +++
Sbjct: 1 MDVTIAEKRNYYVGETNNQLREGYGVYCYANKFFRYEGEWLKGKKHGHGKLLMGDGSYYEGEFKDGEIDGHGYRKWERTGDDYSGEFLKGELHGHGVMNYNDGSQYRGEFCNNQRHGTGVLTDRDGNEYEGAWYKNKKHGQGVQTYFNGDEYEGEWVEGARHGHGELNCVDGSIYEGQWRANMFNGEGSMVHASGVTYEGLWINGKPAAEGKEIVVRLPTNQTHIEVPQGKKFSLQFEIVDVNKEPVVGVHGREFRITAGYRYLPPSKQGNQSILELIEDMEEKPITTPFGYDVLPYPLLENVGVSEETDEIIKNKHRMSPVNARIFGEETIHETHSTEPHKNEDEVEPDDGSIISDNRHIQSEVMLSVEVDDVDVTFSINPPPAPQRSAPDGSVEFKDLYLPSAPPTYRPLLLDEGKRSKGSRNTSAASTSSTSVNESKPGKAGKAKNE-EERGAKPGEYLMIVTEVTNPPFLGDNLPPAFVVVKV 486
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. TrEMBL
Match: A0A1W5BE42 (MORN repeat-containing protein 1-like isoform X1 OS=Ciona intestinalis OX=7719 GN=LOC100176954 PE=4 SV=1) HSP 1 Score: 287.345 bits (734), Expect = 9.260e-87 Identity = 174/512 (33.98%), Postives = 270/512 (52.73%), Query Frame = 1
Query: 64 LKMEIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPC----KIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVND--NNSLFELIEQIDSKPVETTY-YPVLLVPL------TDKPPQWVQSLENASHNKIRL-------------PHLFE-----------SDESNSQPPESTETDLTDAPLCNDLCLDPVIQETK-NGSVDFINLFIQ------QPKLAAGSCLQSDSASEFINSASVSATSIKQNK-DQSLSEKN----------IKHKELG--------DEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
+ + I ++ N+Y+GETN LREG+GVY Y NKFF+YEGEW KGKKHGHG+ +M DGS+YEGEF++GEI G G R W +TG+ Y GEF GE+ G G+M Y +G +Y G++ +N R G G LT +G+ YEG +YK+K HG+G+ NG Y G W+ G +HGHG++ DGS+YEGQ+ N+F+GEG++ H G+ Y GLW P +I ++ ++ QG F + ++ N E V GR R+TAG +Y P + N S+ ELIE ++ KP+ T + Y VL PL +++ + +++ S R+ PH E SD + Q ++ D + + P Q + +GSV+F +L++ +P L S AS + S +S++ K +S +N + + G +E+ K GEY++I+ ++T PF+ + L + +++
Sbjct: 1 MDVTIAEKRNYYVGETNNQLREGYGVYCYANKFFRYEGEWLKGKKHGHGKLLMGDGSYYEGEFKDGEIDGHGYRKWERTGDDYSGEFLKGELHGHGVMNYNDGSQYRGEFCNNQRHGTGVLTDRDGNEYEGAWYKNKKHGQGVQTYFNGDEYEGEWVEGARHGHGELNCVDGSIYEGQWRANMFNGEGSMVHASGVTYEGLWINGKPAAEGKEIVVRLPTNQTHIEVPQGKKFSLQFEIVDVNKEPVVGVHGREFRITAGYRYLPPSKQGNQSILELIEDMEEKPITTPFGYDVLPYPLLENVGVSEETDEIIKNKHRMSPVNARIFGEETIHETHSTEPHKNEDEVEPDDGSIISDNRHIQSEVMLSVEVDDVDVTFSINPPPAPQRSAPDGSVEFKDLYLPSAPPTYRPLLLDEVTPASSVASSRRSVGQSSTSSVRSEKGKRSKGSRNTSAASTSSTSVNESKPGKAGKAKNEEERGAKPGEYLMIVTEVTNPPFLGDNLPPAFVVVKV 512
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. TrEMBL
Match: F6PNK8 (Insulin like growth factor 2 OS=Xenopus tropicalis OX=8364 GN=igf2 PE=4 SV=2) HSP 1 Score: 286.189 bits (731), Expect = 1.158e-86 Identity = 164/479 (34.24%), Postives = 255/479 (53.24%), Query Frame = 1
Query: 88 NNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLT-TDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSL--FELIEQIDSKPVETTY-YPVLLVPLTDKPPQWVQSLENASHNKIRLP-------------HLFESDESNSQPPESTETDLT---------DAPLCNDLCLDPVIQETKNGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASVSA-----TSIKQNK-DQSLSEKNIKHK------ELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQI 1410
+ +Y G K LR+G+G+YVYEN FF+YEG+W+ GKKHGHG+ + DGS+YEGEF +GEI G G RYW +GN Y GEF GE+ G G+M Y +G Y G+++ +EG+G L G Y G F+ +K +G G M+ MNG Y G WI + GHG + DGS+YEGQ+ ++F+G+G + H G++Y GLW P KM + DI++ QG + + + T+ GE V E+GR L+++AG+KY N + +L ELIE ++ KP ++ + Y + PLT Q+ + H K +P HL E+ S S E L + +++C P + G F ++ + P A C ++D + +SA ++ Q K + S SE +IK + +L D + GEY++I++D+T PF+ L ++ ++++
Sbjct: 11 SRYYTGGIKKQLRDGYGLYVYENSFFRYEGQWKSGKKHGHGKLLFKDGSYYEGEFADGEITGNGLRYWSSSGNKYSGEFQTGEIHGHGVMQYKDGGRYEGEFVFGIKEGHGLLMDKEGQTYSGAFHNNKKYGVGQMKFMNGDHYEGDWILDQRQGHGVLQCTDGSIYEGQWRNDVFNGQGIMIHCSGVIYDGLWINGHPAVAAKKMVIIGEDIINFIQGSRSTVHVQIQTEEGETVKNENGRVLKISAGIKYSQPNRSQTLSFLELIEDLEEKPFQSPFGYECINYPLT-------QTASRSQHQKDTIPFNSQSGSAPFGGSHLSENSISEHGFVASQEAGLALNSSGEYPEISGTTDEMCFLPSNVRVEAGCAIFSDIMLGPPS-AKFHCDETDKNKGKKPNGKISAEKTEKMTVSQEKIEDSRSETSIKDRKVKKDNQLQDSNIVRPGEYIIIVKDVTSPPFLGYTLPPVFKRVRL 481
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. TrEMBL
Match: A0A4W5N8Y7 (MORN repeat containing 1 OS=Hucho hucho OX=62062 GN=MORN1 PE=4 SV=1) HSP 1 Score: 275.789 bits (704), Expect = 1.370e-82 Identity = 173/504 (34.33%), Postives = 257/504 (50.99%), Query Frame = 1
Query: 64 LKMEIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLT-TDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVK---YQPVNDNNSLFELIEQIDSKPVETTY-YPVLLVPLTDK-----------PPQWVQSLE----NASHNKIRLPH-LFESDESNSQPPESTET----DLTDAPLCNDLCLDPVIQETKNGSVDFINLFIQQP-----KLAAGSCLQSDSASEFINSASVSATSIKQNKDQ-------SLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQIHPFPISDSLQESTSKNSQ 1464
+K +I++ + +Y+GE + R GFGVYVY N FF YEGEW KG+KHGHG+ +M DGS+YEGEF +GEI G G R+W KTG Y G+F GE+ G G+M GNG+ Y G++ R+GNG L +G YEG F+++K HGEG M NG Y G W+ + GHG M DGSVYEGQ+ NLF+G+G + H GI+Y G+W P +K+ + D+L+ FQ F + + L T+ GE E+GR L+++ G++ P SL +++E P+ T + + V+ PL ++ P V ++ +A + LP ES + PP T D A D P Q + G F NL + P L+ + + N A + Q+ + S NIK + D + + GEYV++++D+T PF L ++ +++ P ++ SKNSQ
Sbjct: 4 VKKQIRN-SRYYVGEVKNLTRNGFGVYVYPNSFFCYEGEWSKGEKHGHGKLLMKDGSYYEGEFAHGEIEGNGSRFWAKTGVSYSGQFSGGELHGCGVMQKGNGERYEGEFSYGLRDGNGFLVDKDGQAYEGSFHQNKRHGEGQMHYRNGDQYEGGWLLDQQQGHGVMHFGDGSVYEGQWRNNLFNGQGIMIHCSGIIYEGVWANGRPLGGASKVVIEGGDVLEVFQETPFCVEVQLQTEVGEKATGENGRVLQVSTGIRLCDLSPSTTPASLLKMMEDNKETPIPTPFGFQVVSYPLMERAFGSQDSIGTTAPLTVAAVAAKSGSAQADSPLLPEGECESGSGSDGPPLRGGTPSYLDGLFAGQEEDSTPPPANQRVEEGQAKFQNLLLAPPPHDFLPYQLMDELEKRNVKKPSNRAPTDRPGLSQDMNSERRSSMGSCFTSNIKKSSI-DSRSVRPGEYVIMVKDVTNPPFQGQTLPPVFALLRLFP-------AKTKSKNSQ 498
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Cavefish
Match: rsph10b (radial spoke head 10 homolog B [Source:NCBI gene;Acc:103028242]) HSP 1 Score: 125.561 bits (314), Expect = 6.114e-30 Identity = 77/209 (36.84%), Postives = 106/209 (50.72%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE--YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGKMTM----------PDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
+ Y G L G G Y + + KYEGE+ GHG + DGS YEGE G G G + KT +VYRG++H G+ G GI+ Y Y GDW +N REG G Y +G++Y+G++ HGEG MR + YSG W+ G +HG G T P + Y+G+F + HG+GT + G Y+G W+ N
Sbjct: 90 HVYKGRFANGLMHGHGEYTWADGV-KYEGEFVLNAPVGHGIYTWLDGSIYEGEVWYGIRHGFGTYHCAKTSSVYRGQWHQGKRHGKGIICYNRERTSWYEGDWKNNCREGWGVRCYPSGNIYQGQWKNDARHGEGTMRWIQLNQQYSGQWVAGVQHGQGTHTWVLRRGLGSQYPRSNEYKGEFVQGMRHGQGTFLYASGATYSGGWQHN 297 HSP 2 Score: 101.679 bits (252), Expect = 2.964e-22 Identity = 62/183 (33.88%), Postives = 93/183 (50.82%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFV--MADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN-GDEYHGDWISNSREGNGQLT----------YANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQF 600
+ Y GE +R GFG Y Y G+W +GK+HG G S+YEG+++N G G R +P +GN+Y+G++ N G G M + +Y G W++ + G G T Y + Y+GEF + HG+G +G+ YSG W KHG GK+T +G ++EG+F
Sbjct: 136 SIYEGEVWYGIRHGFGTYHCAKTSSVYRGQWHQGKRHGKGIICYNRERTSWYEGDWKNNCREGWGVRCYP-SGNIYQGQWKNDARHGEGTMRWIQLNQQYSGQWVAGVQHGQGTHTWVLRRGLGSQYPRSNEYKGEFVQGMRHGQGTFLYASGATYSGGWQHNKKHGQGKVTFKNGRIFEGEF 317 HSP 3 Score: 78.1814 bits (191), Expect = 9.222e-15 Identity = 46/145 (31.72%), Postives = 76/145 (52.41%), Query Frame = 1
Query: 79 KDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYW----------PKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKI 477
++R ++Y G+ REG+GV Y + Y+G+W+ +HG G R++ + Y G++ G G+G W P++ N Y+GEF G G G Y +G Y G W N + G G++T+ NG ++EGEF + ++
Sbjct: 181 RERTSWYEGDWKNNCREGWGVRCYPSGNI-YQGQWKNDARHGEGTMRWIQLNQQ-YSGQWVAGVQHGQGTHTWVLRRGLGSQYPRS-NEYKGEFVQGMRHGQGTFLYASGATYSGGWQHNKKHGQGKVTFKNGRIFEGEFIEDRM 322 HSP 4 Score: 72.4034 bits (176), Expect = 6.431e-13 Identity = 47/150 (31.33%), Postives = 71/150 (47.33%), Query Frame = 1
Query: 301 GNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLM-NGSIYSGYWICGNKHGHGKM-------------------------TMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLW 669
G+VY+G F NG M G G + +G +Y G+++ N+ G+G T+ +G +YEGE + HG G S+Y G W G +HG G + P G++Y+GQ+ + HGEGT+ I Y+G W
Sbjct: 89 GHVYKGRFANGLMHGHGEYTWADGVKYEGEFVLNAPVGHGIYTWLDGSIYEGEVWYGIRHGFGTYHCAKTSSVYRGQWHQGKRHGKGIICYNRERTSWYEGDWKNNCREGWGVRCYPSGNIYQGQWKNDARHGEGTMRWIQLNQQYSGQW 238 HSP 5 Score: 58.151 bits (139), Expect = 1.701e-8 Identity = 36/103 (34.95%), Postives = 48/103 (46.60%), Query Frame = 1
Query: 373 DEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGI--LYTGLWEQ 675
D Y G+ G G + G VY+G F +HG G +G Y G ++ GHG T DGS+YEG+ Y + HG GT +H +Y G W Q
Sbjct: 67 DRYEGERCGELFHGEGAADFLGGHVYKGRFANGLMHGHGEYTWADGVKYEGEFVLNAPVGHGIYTWLDGSIYEGEVWYGIRHGFGT-YHCAKTSSVYRGQWHQ 168
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Cavefish
Match: rsph10b (radial spoke head 10 homolog B [Source:NCBI gene;Acc:103028242]) HSP 1 Score: 124.79 bits (312), Expect = 9.988e-30 Identity = 77/209 (36.84%), Postives = 106/209 (50.72%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE--YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGKMTM----------PDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
+ Y G L G G Y + + KYEGE+ GHG + DGS YEGE G G G + KT +VYRG++H G+ G GI+ Y Y GDW +N REG G Y +G++Y+G++ HGEG MR + YSG W+ G +HG G T P + Y+G+F + HG+GT + G Y+G W+ N
Sbjct: 90 HVYKGRFANGLMHGHGEYTWADGV-KYEGEFVLNAPVGHGIYTWLDGSIYEGEVWYGIRHGFGTYHCAKTSSVYRGQWHQGKRHGKGIICYNRERTSWYEGDWKNNCREGWGVRCYPSGNIYQGQWKNDARHGEGTMRWIQLNQQYSGQWVAGVQHGQGTHTWVLRRGLGSQYPRSNEYKGEFVQGMRHGQGTFLYASGATYSGGWQHN 297 HSP 2 Score: 101.293 bits (251), Expect = 4.174e-22 Identity = 62/183 (33.88%), Postives = 93/183 (50.82%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFV--MADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN-GDEYHGDWISNSREGNGQLT----------YANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQF 600
+ Y GE +R GFG Y Y G+W +GK+HG G S+YEG+++N G G R +P +GN+Y+G++ N G G M + +Y G W++ + G G T Y + Y+GEF + HG+G +G+ YSG W KHG GK+T +G ++EG+F
Sbjct: 136 SIYEGEVWYGIRHGFGTYHCAKTSSVYRGQWHQGKRHGKGIICYNRERTSWYEGDWKNNCREGWGVRCYP-SGNIYQGQWKNDARHGEGTMRWIQLNQQYSGQWVAGVQHGQGTHTWVLRRGLGSQYPRSNEYKGEFVQGMRHGQGTFLYASGATYSGGWQHNKKHGQGKVTFKNGRIFEGEF 317 HSP 3 Score: 77.7962 bits (190), Expect = 1.220e-14 Identity = 46/145 (31.72%), Postives = 76/145 (52.41%), Query Frame = 1
Query: 79 KDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYW----------PKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKI 477
++R ++Y G+ REG+GV Y + Y+G+W+ +HG G R++ + Y G++ G G+G W P++ N Y+GEF G G G Y +G Y G W N + G G++T+ NG ++EGEF + ++
Sbjct: 181 RERTSWYEGDWKNNCREGWGVRCYPSGNI-YQGQWKNDARHGEGTMRWIQLNQQ-YSGQWVAGVQHGQGTHTWVLRRGLGSQYPRS-NEYKGEFVQGMRHGQGTFLYASGATYSGGWQHNKKHGQGKVTFKNGRIFEGEFIEDRM 322 HSP 4 Score: 72.0182 bits (175), Expect = 8.165e-13 Identity = 44/129 (34.11%), Postives = 66/129 (51.16%), Query Frame = 1
Query: 301 GNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLM-NGSIYSGYWICGNKHGHGKM--TMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
G+VY+G F NG M G G + +G +Y G+++ N+ G+G T+ +G +YEGE + HG G S+Y G W G +HG G + S YEG + N G G + G +Y G W+ +
Sbjct: 89 GHVYKGRFANGLMHGHGEYTWADGVKYEGEFVLNAPVGHGIYTWLDGSIYEGEVWYGIRHGFGTYHCAKTSSVYRGQWHQGKRHGKGIICYNRERTSWYEGDWKNNCREGWGVRCYPSGNIYQGQWKND 217 HSP 5 Score: 57.7658 bits (138), Expect = 1.977e-8 Identity = 36/103 (34.95%), Postives = 48/103 (46.60%), Query Frame = 1
Query: 373 DEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGI--LYTGLWEQ 675
D Y G+ G G + G VY+G F +HG G +G Y G ++ GHG T DGS+YEG+ Y + HG GT +H +Y G W Q
Sbjct: 67 DRYEGERCGELFHGEGAADFLGGHVYKGRFANGLMHGHGEYTWADGVKYEGEFVLNAPVGHGIYTWLDGSIYEGEVWYGIRHGFGT-YHCAKTSSVYRGQWHQ 168
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Cavefish
Match: morn3 (MORN repeat-containing protein 3 [Source:NCBI gene;Acc:103031534]) HSP 1 Score: 98.9821 bits (245), Expect = 6.006e-23 Identity = 66/171 (38.60%), Postives = 92/171 (53.80%), Query Frame = 1
Query: 103 GETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMAD-GSFYEGEFQNGEICGKG--ERYWPKTGN---VYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD-GSVYEG 594
E N +LR F V +Y GEW + +KHG G V G Y+GE++ G+ G G + P + N +Y GE+ N + G G+ Y Y G W+ + R G+G++ Y NGDVYEGE+ K K HG+G++ L NG+ Y G W G K+G G D G +YEG
Sbjct: 11 AEKNGVLRTVFSV-----TGDQYTGEWLQNRKHGKGTQVWKRAGVVYDGEWRFGKRDGFGTLSKQSPPSNNYEVIYSGEWKNDKKEGFGMEVYSPSSLYEGQWVEHERSGSGRMFYPNGDVYEGEWLKDKPHGQGVLTLANGNRYEGSWKDGRKNGPGCFFYLDKGQLYEG 176 HSP 2 Score: 89.7373 bits (221), Expect = 1.056e-19 Identity = 56/174 (32.18%), Postives = 89/174 (51.15%), Query Frame = 1
Query: 184 QKGKKHGHGRFVMA-DGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE------YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLWEQNL 681
+K +K+G R V + G Y GE+ GKG + W + G VY GE+ G+ G G + + Y G+W ++ +EG G Y+ +YEG++ +H+ G G M NG +Y G W+ HG G +T+ +G+ YEG + +G G F++ G LY G W ++
Sbjct: 9 KKAEKNGVLRTVFSVTGDQYTGEWLQNRKHGKGTQVWKRAGVVYDGEWRFGKRDGFGTLSKQSPPSNNYEVIYSGEWKNDKKEGFGMEVYSPSSLYEGQWVEHERSGSGRMFYPNGDVYEGEWLKDKPHGQGVLTLANGNRYEGSWKDGRKNGPGCFFYLDKGQLYEGFWVDDV 182 HSP 3 Score: 57.7658 bits (138), Expect = 6.770e-9 Identity = 39/118 (33.05%), Postives = 57/118 (48.31%), Query Frame = 1
Query: 352 IMFYGNGDEYHGDWISNSREGNG-QLTYANGDVYEGEFYKHKIHGEGIMRLMNGS------IYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLP 684
+F GD+Y G+W+ N + G G Q+ G VY+GE+ K G G + + IYSG W K G G S+YEGQ+ + G G +F+ G +Y G W ++ P
Sbjct: 19 TVFSVTGDQYTGEWLQNRKHGKGTQVWKRAGVVYDGEWRFGKRDGFGTLSKQSPPSNNYEVIYSGEWKNDKKEGFGMEVYSPSSLYEGQWVEHERSGSGRMFYPNGDVYEGEWLKDKP 136
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Cavefish
Match: als2b (alsin Rho guanine nucleotide exchange factor ALS2 b [Source:ZFIN;Acc:ZDB-GENE-080929-1]) HSP 1 Score: 91.6633 bits (226), Expect = 6.773e-19 Identity = 58/182 (31.87%), Postives = 88/182 (48.35%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFK----YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGE----RYWPKTGNVYRGEFHNGEMTGTGIM-FYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSG----YWICGNKHGHGKMTMPDGSVYEGQFN 603
Y G L +G+G Y+ NK Y+G W+ GK HG G F A G YEG FQ+ G G + + +V+ G++ + + TG G+ G++Y G W + R+GNG + G YEG F +K+ G G++ + + + G W G G +TMP+G EG F+
Sbjct: 1104 YTGTFKNGLEDGYGDYIVPNKNLNKSDHYQGHWKDGKMHGFGNFRYATGELYEGSFQDNMRHGHGMLRSGKLNSTSPSVFIGQWLHDKKTGYGVFDDITRGEKYMGLWQEDLRQGNGVIVTQFGLYYEGAFSNNKMMGTGVLLSEDDTTFEGDFSDDWTLS---GKGTLTMPNGDYIEGSFS 1282 HSP 2 Score: 81.2629 bits (199), Expect = 1.316e-15 Identity = 53/166 (31.93%), Postives = 75/166 (45.18%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWP----KTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREG-----NGQLTYANGDVYEGEFYKHKIHGEGIM-RLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLF 636
YEG W GK +G G DG Y G F+NG G G+ P + Y+G + +G+M G G Y G+ Y G + N R G +G+L + V+ G++ K G G+ + G Y G W + G+G + G YEG F+ N G G L
Sbjct: 1081 YEGRWLAGKPNGRGVLKWPDGRMYTGTFKNGLEDGYGDYIVPNKNLNKSDHYQGHWKDGKMHGFGNFRYATGELYEGSFQDNMRHGHGMLRSGKLNSTSPSVFIGQWLHDKKTGYGVFDDITRGEKYMGLWQEDLRQGNGVIVTQFGLYYEGAFSNNKMMGTGVLL 1246
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Cavefish
Match: als2b (alsin Rho guanine nucleotide exchange factor ALS2 b [Source:ZFIN;Acc:ZDB-GENE-080929-1]) HSP 1 Score: 91.6633 bits (226), Expect = 6.782e-19 Identity = 58/182 (31.87%), Postives = 88/182 (48.35%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFK----YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGE----RYWPKTGNVYRGEFHNGEMTGTGIM-FYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSG----YWICGNKHGHGKMTMPDGSVYEGQFN 603
Y G L +G+G Y+ NK Y+G W+ GK HG G F A G YEG FQ+ G G + + +V+ G++ + + TG G+ G++Y G W + R+GNG + G YEG F +K+ G G++ + + + G W G G +TMP+G EG F+
Sbjct: 1113 YTGTFKNGLEDGYGDYIVPNKNLNKSDHYQGHWKDGKMHGFGNFRYATGELYEGSFQDNMRHGHGMLRSGKLNSTSPSVFIGQWLHDKKTGYGVFDDITRGEKYMGLWQEDLRQGNGVIVTQFGLYYEGAFSNNKMMGTGVLLSEDDTTFEGDFSDDWTLS---GKGTLTMPNGDYIEGSFS 1291 HSP 2 Score: 81.2629 bits (199), Expect = 1.318e-15 Identity = 53/166 (31.93%), Postives = 75/166 (45.18%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWP----KTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREG-----NGQLTYANGDVYEGEFYKHKIHGEGIM-RLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLF 636
YEG W GK +G G DG Y G F+NG G G+ P + Y+G + +G+M G G Y G+ Y G + N R G +G+L + V+ G++ K G G+ + G Y G W + G+G + G YEG F+ N G G L
Sbjct: 1090 YEGRWLAGKPNGRGVLKWPDGRMYTGTFKNGLEDGYGDYIVPNKNLNKSDHYQGHWKDGKMHGFGNFRYATGELYEGSFQDNMRHGHGMLRSGKLNSTSPSVFIGQWLHDKKTGYGVFDDITRGEKYMGLWQEDLRQGNGVIVTQFGLYYEGAFSNNKMMGTGVLL 1255
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Sea Lamprey
Match: RSPH10B2 (radial spoke head 10 homolog B2 [Source:HGNC Symbol;Acc:HGNC:34385]) HSP 1 Score: 85.5001 bits (210), Expect = 5.756e-18 Identity = 67/227 (29.52%), Postives = 99/227 (43.61%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE--YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLM------NGSI----------------------------YSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTG 663
N Y G + G G YV+ + ++EG++ GHG + DGS Y G +NG G+G K Y G ++ E G GI++Y E Y G+W N R G G Y +G++YEG++ ++ HGEG MR + NG Y G W G++HG G+ G+ Y+G++ + HG GT G +Y G
Sbjct: 6 NVYSGSFCNNMMHGKGKYVWADGV-EFEGDFWLNAMVGHGTYQWPDGSKYTGNVENGVRHGQGTLTVSKPFVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGKPDGRGAHKWLVKRVGCSQYPMCNEYHGEWAAGHRHGQGEFLYASGAQYKGEWRQDRKHGSGTFTCKSGQIYEG 231 HSP 2 Score: 75.0998 bits (183), Expect = 1.375e-14 Identity = 56/181 (30.94%), Postives = 77/181 (42.54%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADG--SFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN-GDEYHGDWISNSREGNGQLTYANGDV----------YEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQF 600
Y G +R G G F Y G W ++HG G + S+Y GE+ + G G R +P +GN+Y G++ N E G G M + EY+G W +G G + V Y GE+ HG+G +G+ Y G W KHG G T G +YEG F
Sbjct: 54 YTGNVENGVRHGQGTLTVSKPFVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYP-SGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGKPDGRGAHKWLVKRVGCSQYPMCNEYHGEWAAGHRHGQGEFLYASGAQYKGEWRQDRKHGSGTFTCKSGQIYEGSF 233 HSP 3 Score: 71.633 bits (174), Expect = 1.344e-13 Identity = 54/156 (34.62%), Postives = 76/156 (48.72%), Query Frame = 1
Query: 229 GSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDV-YEGEFYKHKIHGEGIMRL--MNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGIL-YTGLWEQNLP 684
G+ Y G F N + GKG+ W G + G+F M G G + +G +Y G+ + R G G LT + V Y G +Y + HG+GI+ S Y G W +HG G P G++YEGQ+ N HGEG + I + Y G W+ P
Sbjct: 5 GNVYSGSFCNNMMHGKGKYVWAD-GVEFEGDFWLNAMVGHGTYQWPDGSKYTGNVENGVRHGQGTLTVSKPFVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGKP 159 HSP 4 Score: 68.5514 bits (166), Expect = 1.452e-12 Identity = 43/139 (30.94%), Postives = 72/139 (51.80%), Query Frame = 1
Query: 79 KDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYW--PKTG-------NVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEF 462
+ R ++Y GE + +R G+G+ Y + YEG+W ++HG G R++ Y G++++G+ G+G W + G N Y GE+ G G G Y +G +Y G+W + + G+G T +G +YEG F
Sbjct: 97 EKRESWYCGEWHHNMRHGWGIRRYPSGNI-YEGQWLNNERHGEGCMRWITLMQE-YNGQWKHGKPDGRGAHKWLVKRVGCSQYPMCNEYHGEWAAGHRHGQGEFLYASGAQYKGEWRQDRKHGSGTFTCKSGQIYEGSF 233 HSP 5 Score: 50.8322 bits (120), Expect = 5.677e-7 Identity = 34/111 (30.63%), Postives = 58/111 (52.25%), Query Frame = 1
Query: 358 FYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSV-YEGQFNYNLFHGEGTLFH--ICGILYTGLWEQNL 681
FY G+ Y G + +N G G+ +A+G +EG+F+ + + G G + +GS Y+G G +HG G +T+ V Y G + + HG+G +++ Y G W N+
Sbjct: 1 FYEGGNVYSGSFCNNMMHGKGKYVWADGVEFEGDFWLNAMVGHGTYQWPDGSKYTGNVENGVRHGQGTLTVSKPFVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNM 111
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Sea Lamprey
Match: RSPH10B2 (radial spoke head 10 homolog B2 [Source:HGNC Symbol;Acc:HGNC:34385]) HSP 1 Score: 81.6481 bits (200), Expect = 1.065e-16 Identity = 58/190 (30.53%), Postives = 83/190 (43.68%), Query Frame = 1
Query: 202 GHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE--YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLM------NGSI----------------------------YSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTG 663
GHG + DGS Y G +NG G+G K Y G ++ E G GI++Y E Y G+W N R G G Y +G++YEG++ ++ HGEG MR + NG Y G W G++HG G+ G+ Y+G++ + HG GT G +Y G
Sbjct: 3 GHGTYQWPDGSKYTGNVENGVRHGQGTLTVSKPFVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGKPDGRGAHKWLVKRVGCSQYPMCNEYHGEWAAGHRHGQGEFLYASGAQYKGEWRQDRKHGSGTFTCKSGQIYEG 192 HSP 2 Score: 77.0258 bits (188), Expect = 2.583e-15 Identity = 50/157 (31.85%), Postives = 73/157 (46.50%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFK-YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTG----------TGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWI 534
Y G R G G+ Y+ K Y GEW +HG G G+ YEG++ N E G+G W Y G++ +G+ G G Y +EYHG+W + R G G+ YA+G Y+GE+ + + HG G +G IY G ++
Sbjct: 39 YSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGKPDGRGAHKWLVKRVGCSQYPMCNEYHGEWAAGHRHGQGEFLYASGAQYKGEWRQDRKHGSGTFTCKSGQIYEGSFV 195 HSP 3 Score: 77.0258 bits (188), Expect = 2.653e-15 Identity = 56/181 (30.94%), Postives = 77/181 (42.54%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADG--SFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN-GDEYHGDWISNSREGNGQLTYANGDV----------YEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQF 600
Y G +R G G F Y G W ++HG G + S+Y GE+ + G G R +P +GN+Y G++ N E G G M + EY+G W +G G + V Y GE+ HG+G +G+ Y G W KHG G T G +YEG F
Sbjct: 15 YTGNVENGVRHGQGTLTVSKPFVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYP-SGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGKPDGRGAHKWLVKRVGCSQYPMCNEYHGEWAAGHRHGQGEFLYASGAQYKGEWRQDRKHGSGTFTCKSGQIYEGSF 194 HSP 4 Score: 70.0922 bits (170), Expect = 4.411e-13 Identity = 43/139 (30.94%), Postives = 72/139 (51.80%), Query Frame = 1
Query: 79 KDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYW--PKTG-------NVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEF 462
+ R ++Y GE + +R G+G+ Y + YEG+W ++HG G R++ Y G++++G+ G+G W + G N Y GE+ G G G Y +G +Y G+W + + G+G T +G +YEG F
Sbjct: 58 EKRESWYCGEWHHNMRHGWGIRRYPSGNI-YEGQWLNNERHGEGCMRWITLMQE-YNGQWKHGKPDGRGAHKWLVKRVGCSQYPMCNEYHGEWAAGHRHGQGEFLYASGAQYKGEWRQDRKHGSGTFTCKSGQIYEGSF 194
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Sea Lamprey
Match: morn2 (MORN repeat containing 2 [Source:ZFIN;Acc:ZDB-GENE-060825-230]) HSP 1 Score: 62.003 bits (149), Expect = 4.664e-12 Identity = 35/88 (39.77%), Postives = 48/88 (54.55%), Query Frame = 1
Query: 430 YANGDVYEGEFYKHK-----IHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
+ NGD YEGE+ K + HG G R GSIY+G W G G++ G+VYEG F+ N++HG GT G+ Y G ++ N
Sbjct: 4 FPNGDKYEGEYSKSEDGVMERHGTGTHRSAGGSIYTGQWKYDKMEGTGRLVYLSGAVYEGSFHDNMYHGTGTYTWPSGVKYIGSFQHN 91 HSP 2 Score: 55.0694 bits (131), Expect = 1.285e-9 Identity = 35/120 (29.17%), Postives = 57/120 (47.50%), Query Frame = 1
Query: 367 NGDEYHGDWISNS-----REGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKL 711
NGD+Y G++ + R G G A G +Y G++ K+ G G + ++G++Y G + HG G T P G Y G F +N GEG G +TG++ + + K+ +
Sbjct: 6 NGDKYEGEYSKSEDGVMERHGTGTHRSAGGSIYTGQWKYDKMEGTGRLVYLSGAVYEGSFHDNMYHGTGTYTWPSGVKYIGSFQHNKLKGEGMFTDTEGQEWTGMFHKKAAPGLKLKLNM 125 HSP 3 Score: 47.7506 bits (112), Expect = 4.787e-7 Identity = 37/106 (34.91%), Postives = 54/106 (50.94%), Query Frame = 1
Query: 166 KYEGEWQKGK-----KHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYK 468
KYEGE+ K + +HG G A GS Y G+++ ++ G G R +G VY G FH+ GTG + +G +Y G + N +G G T G + G F+K
Sbjct: 9 KYEGEYSKSEDGVMERHGTGTHRSAGGSIYTGQWKYDKMEGTG-RLVYLSGAVYEGSFHDNMYHGTGTYTWPSGVKYIGSFQHNKLKGEGMFTDTEGQEWTGMFHK 113
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003398.1 (pep scaffold:Pmarinus_7.0:GL476560:333524:339285:-1 gene:ENSPMAG00000003108.1 transcript:ENSPMAT00000003398.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 62.003 bits (149), Expect = 8.447e-12 Identity = 33/93 (35.48%), Postives = 55/93 (59.14%), Query Frame = 1
Query: 166 KYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGD 444
+Y+GEW++G++HG G+ DG+ Y G+F+NG G G +P G+ + GEF G+ G G+ +G + G++ + EG G LT+ +G
Sbjct: 15 EYQGEWKEGRRHGLGQLRFTDGTHYLGQFENGLFSGCGVLAFPD-GSRFEGEFSQGKFHGVGVFSRSDGMMFEGEFKNGHVEGYGLLTFPDGS 106 HSP 2 Score: 58.5362 bits (140), Expect = 1.150e-10 Identity = 33/95 (34.74%), Postives = 52/95 (54.74%), Query Frame = 1
Query: 298 TGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGS 582
TG Y+GE+ G G G + + +G Y G + + G G L + +G +EGEF + K HG G+ +G ++ G + G+ G+G +T PDGS
Sbjct: 12 TGEEYQGEWKEGRRHGLGQLRFTDGTHYLGQFENGLFSGCGVLAFPDGSRFEGEFSQGKFHGVGVFSRSDGMMFEGEFKNGHVEGYGLLTFPDGS 106 HSP 3 Score: 58.151 bits (139), Expect = 1.449e-10 Identity = 31/83 (37.35%), Postives = 47/83 (56.63%), Query Frame = 1
Query: 415 NGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTG 663
G TYA G+ Y+GE+ + + HG G +R +G+ Y G + G G G + PDGS +EG+F+ FHG G G+++ G
Sbjct: 5 KGSFTYATGEEYQGEWKEGRRHGLGQLRFTDGTHYLGQFENGLFSGCGVLAFPDGSRFEGEFSQGKFHGVGVFSRSDGMMFEG 87 HSP 4 Score: 57.7658 bits (138), Expect = 2.485e-10 Identity = 33/95 (34.74%), Postives = 47/95 (49.47%), Query Frame = 1
Query: 349 GIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTL 633
G Y G+EY G+W R G GQL + +G Y G+F G G++ +GS + G + G HG G + DG ++EG+F G G L
Sbjct: 6 GSFTYATGEEYQGEWKEGRRHGLGQLRFTDGTHYLGQFENGLFSGCGVLAFPDGSRFEGEFSQGKFHGVGVFSRSDGMMFEGEFKNGHVEGYGLL 100
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002910.1 (pep scaffold:Pmarinus_7.0:GL480350:1227:27530:-1 gene:ENSPMAG00000002661.1 transcript:ENSPMAT00000002910.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 62.7734 bits (151), Expect = 6.876e-11 Identity = 43/147 (29.25%), Postives = 73/147 (49.66%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKG----ERYWPKTGNVYRGEFHNGEMTGTGIM-FYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICG-NKHGHGKMTMPDGSVYE 591
Y G+W+ + HG G A+G YEG F NG G G + + ++Y G++ N G G+ G++Y G W+++ R GNG + G YE F +++ G+G++ + + Y G + +G G +T+P+G E
Sbjct: 27 YCGQWKAARMHGQGAIRYANGDVYEGGFSNGARHGHGVLRSGSHTSTSSSLYIGQWANDCKCGYGVFDDITRGEKYMGMWMNDCRHGNGVVVSQFGLYYECVFSSNRMVGQGVLLSEDDTRYEGEFTADLALNGKGVLTLPNGDAIE 173 HSP 2 Score: 55.8398 bits (133), Expect = 9.814e-9 Identity = 36/122 (29.51%), Postives = 47/122 (38.52%), Query Frame = 1
Query: 358 FYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMR-----------------------------LMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLF 636
G D Y G W + G G + YANGDVYEG F HG G++R + G Y G W+ +HG+G + G YE F+ N G+G L
Sbjct: 20 LLGKDDVYCGQWKAARMHGQGAIRYANGDVYEGGFSNGARHGHGVLRSGSHTSTSSSLYIGQWANDCKCGYGVFDDITRGEKYMGMWMNDCRHGNGVVVSQFGLYYECVFSSNRMVGQGVLL 141
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Nematostella
Match: EDO34090 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQC6]) HSP 1 Score: 218.779 bits (556), Expect = 4.644e-68 Identity = 106/222 (47.75%), Postives = 147/222 (66.22%), Query Frame = 1
Query: 130 GFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTD-ILDCFQGHTFQISLTLITDNGEIV 792
GFGV+ YENKFF+YEGEW KGKKHGHG+ +MADGSFYEG+F +GEI G G RYW + N Y G+F GE+ G G+M YG+G +Y G+W++N REG+G+L +G VYEG F++HK HGEG M +NG +Y G W+ + GHG + DG++Y GQ+ + FHGEG++ H G+ Y GLW P +++ + + QG F + T NG+++
Sbjct: 1 GFGVFNYENKFFRYEGEWSKGKKHGHGKLLMADGSFYEGQFMDGEIQGHGFRYWASSRNEYTGQFVKGELHGNGVMKYGDGSQYEGEWMNNRREGSGKLMEKDGSVYEGSFHEHKKHGEGKMIYINGDVYEGDWVKDLRQGHGIIKQEDGTLYAGQWWGDEFHGEGSMVHCSGMAYEGLWVSGRPEMEAVVLRIVGKPVAEVAQGRPFGFEVECCTANGDVI 222
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Nematostella
Match: EDO49962 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RER8]) HSP 1 Score: 111.694 bits (278), Expect = 2.122e-27 Identity = 77/236 (32.63%), Postives = 116/236 (49.15%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENK------FFK----------------YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDC 732
++Y GE + G GV V+ NK F K Y G W K KKHG GR VMA+G Y G F N +CG+GE + K G +Y+G++ N + G G +G Y G+W ++ +G G++ Y N D Y+G ++++ G+GI G IY G + +HGHG M DGS Y+G++ + G++ ++ G Y G WE + + L + L C
Sbjct: 60 DYYHGEWREGEMHGKGVIVFNNKDSLEGVFVKGDIQSEGTLKCTNGLTYVGTWHKSKKHGKGRLVMANGDTYNGNFVNDRMCGEGEMLYAKNGALYKGQWENSQRHGVGTYEAPDGTMYEGEWSADHIQGRGRMIYPNKDSYDGSWFRNMRFGKGIYCFHEG-IYEGQFEYDLRHGHGLMRYNDGSEYDGEWQNDQVKSLGSMDYLGGATYDGPWE------LDRRHGLGRETLKC 288 HSP 2 Score: 96.6709 bits (239), Expect = 2.912e-22 Identity = 65/210 (30.95%), Postives = 104/210 (49.52%), Query Frame = 1
Query: 124 REGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE-----------------------YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEG-IMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNL 681
R G GV ++N+ +YEG ++ +++G G G Y+GE+ + + CG G +P G+ Y GE+ GEM G G++ + N D Y G W + + G G+L ANGD Y G F ++ GEG ++ NG++Y G W +HG G PDG++YEG+++ + G G + + Y G W +N+
Sbjct: 2 RHGHGVLAWQNRT-RYEGHFEDNERNGIGVLTYNTGEKYDGEWLDDKQCGIGTLKYP-NGDYYHGEWREGEMHGKGVIVFNNKDSLEGVFVKGDIQSEGTLKCTNGLTYVGTWHKSKKHGKGRLVMANGDTYNGNFVNDRMCGEGEMLYAKNGALYKGQWENSQRHGVGTYEAPDGTMYEGEWSADHIQGRGRMIYPNKDSYDGSWFRNM 209 HSP 3 Score: 96.2857 bits (238), Expect = 4.908e-22 Identity = 62/170 (36.47%), Postives = 85/170 (50.00%), Query Frame = 1
Query: 193 KKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEG-TLFHICGILYTGLWEQNLPCKIPT 699
++HGHG + + YEG F++ E G G + TG Y GE+ + + G G + Y NGD YHG+W G G + + N D EG F K I EG ++ NG Y G W KHG G++ M +G Y G F + GEG L+ G LY G WE + + T
Sbjct: 1 QRHGHGVLAWQNRTRYEGHFEDNERNGIGVLTY-NTGEKYDGEWLDDKQCGIGTLKYPNGDYYHGEWREGEMHGKGVIVFNNKDSLEGVFVKGDIQSEGTLKCTNGLTYVGTWHKSKKHGKGRLVMANGDTYNGNFVNDRMCGEGEMLYAKNGALYKGQWENSQRHGVGT 169 HSP 4 Score: 65.855 bits (159), Expect = 7.937e-12 Identity = 48/170 (28.24%), Postives = 76/170 (44.71%), Query Frame = 1
Query: 112 NKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGN---------------------VYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHG 558
++M EG +Y +K G+W+ ++HG G + DG+ YEGE+ I G+G +P + +Y G+F G G+M Y +G EY G+W ++ + G + Y G Y+G + + HG G L G++Y G W K G G
Sbjct: 138 DRMCGEGEMLYAKNGALYK--GQWENSQRHGVGTYEAPDGTMYEGEWSADHIQGRGRMIYPNKDSYDGSWFRNMRFGKGIYCFHEGIYEGQFEYDLRHGHGLMRYNDGSEYDGEWQNDQVKSLGSMDYLGGATYDGPWELDRRHGLGRETLKCGTVYEGRWKEDRKCGEG 305
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Nematostella
Match: EDO30644 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T074]) HSP 1 Score: 93.9745 bits (232), Expect = 2.850e-20 Identity = 66/198 (33.33%), Postives = 98/198 (49.49%), Query Frame = 1
Query: 127 EGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN-GDEYH-GDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGKMT----------MPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNL 681
EG G YV+ N YEG+++ G G + DGS YEGE ++G G+G+ VY GE+ +G+ G G++ Y G Y+ G W++N R G + Y G+VYEG++ + HG+G M + Y G W G +HGHG+ + P + Y+G + L HG G + G Y G W N+
Sbjct: 99 EGSGKYVWVNGII-YEGDFKNNVIDGKGLYTWTDGSTYEGEVESGLRHGQGDYSCSNLPAVYSGEWRHGKRHGRGVLKYDREGHSYYDGHWLNNMRHGYARRVYKGGNVYEGDWKDNLRHGDGSMHWYDRDQRYQGQWEYGVQHGHGEHSWFLRRIAGSQYPLRNYYKGNWVNGLRHGYGVFTYASGAKYVGEWASNM 295 HSP 2 Score: 87.4261 bits (215), Expect = 3.618e-18 Identity = 59/173 (34.10%), Postives = 90/173 (52.02%), Query Frame = 1
Query: 169 YEGEW-QKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYAN-GDVYEGEFYKHKIHGEGIMRL--MNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTL-FHICGILYTGLWE 672
YEG+ ++G HG G G Y G F NG++ G G+ W G +Y G+F N + G G+ + +G Y G+ S R G G + +N VY GE+ K HG G+++ S Y G+W+ +HG+ + G+VYEG + NL HG+G++ ++ Y G WE
Sbjct: 65 YEGDKDERGFFHGTGTASFQGGHVYSGSFVNGKMEGSGKYVW-VNGIIYEGDFKNNVIDGKGLYTWTDGSTYEGEVESGLRHGQGDYSCSNLPAVYSGEWRHGKRHGRGVLKYDREGHSYYDGHWLNNMRHGYARRVYKGGNVYEGDWKDNLRHGDGSMHWYDRDQRYQGQWE 236 HSP 3 Score: 84.7297 bits (208), Expect = 2.287e-17 Identity = 66/223 (29.60%), Postives = 98/223 (43.95%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIM-FYGNGDEYHGDWISNSREGNGQLT----------YANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDIL 726
Y GE LR G G Y N Y GEW+ GK+HG G ++ S+Y+G + N G R + K GNVY G++ + G G M +Y Y G W + G+G+ + Y + Y+G + HG G+ +G+ Y G W KHG GK +G V+EG F + + F+ G+ + +P + T M+ T L
Sbjct: 135 YEGEVESGLRHGQGDYSCSNLPAVYSGEWRHGKRHGRGVLKYDREGHSYYDGHWLNNMRHGYARRVY-KGGNVYEGDWKDNLRHGDGSMHWYDRDQRYQGQWEYGVQHGHGEHSWFLRRIAGSQYPLRNYYKGNWVNGLRHGYGVFTYASGAKYVGEWASNMKHGKGKYIFKNGQVFEGTFEQDHML-DFPDFYPSGMTTPDIASAGIPLRPSTPMRAATPFL 355 HSP 4 Score: 75.8702 bits (185), Expect = 1.634e-14 Identity = 49/130 (37.69%), Postives = 68/130 (52.31%), Query Frame = 1
Query: 301 GNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHG--KMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNL 681
G+VY G F NG+M G+G + NG Y GD+ +N +G G T+ +G YEGE HG+G N ++YSG W G +HG G K S Y+G + N+ HG + G +Y G W+ NL
Sbjct: 86 GHVYSGSFVNGKMEGSGKYVWVNGIIYEGDFKNNVIDGKGLYTWTDGSTYEGEVESGLRHGQGDYSCSNLPAVYSGEWRHGKRHGRGVLKYDREGHSYYDGHWLNNMRHGYARRVYKGGNVYEGDWKDNL 215 HSP 5 Score: 66.2402 bits (160), Expect = 1.550e-11 Identity = 43/138 (31.16%), Postives = 68/138 (49.28%), Query Frame = 1
Query: 79 KDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMAD-GSFYEGEFQNGEICGKGERYW---------PKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEF 462
++ +++Y G +R G+ VY+ YEG+W+ +HG G D Y+G+++ G G GE W N Y+G + NG G G+ Y +G +Y G+W SN + G G+ + NG V+EG F
Sbjct: 178 REGHSYYDGHWLNNMRHGYARRVYKGGNV-YEGDWKDNLRHGDGSMHWYDRDQRYQGQWEYGVQHGHGEHSWFLRRIAGSQYPLRNYYKGNWVNGLRHGYGVFTYASGAKYVGEWASNMKHGKGKYIFKNGQVFEGTF 314
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Nematostella
Match: EDO41170 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S530]) HSP 1 Score: 86.2705 bits (212), Expect = 3.191e-19 Identity = 62/194 (31.96%), Postives = 94/194 (48.45%), Query Frame = 1
Query: 115 KMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADG-SFYEGEFQNGEICGKGERYWPKTG---NVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLP 684
K ++G VY +Y GEW KK+G G + Y+G++++ CG G +T +Y G + N + G G FY + Y G+W ++ R G G++ Y++G VYEGE+Y K +GEG++RL N + Y G W G KHG G +F+ F G YTG+W ++P
Sbjct: 20 KAQKKGVHHTVYSVNGDQYTGEWNGNKKNGKGTMQWKKSKAIYDGDWKDDRRCGYGTYSIKETSGYRKIYSGGWKNDKRHGYGTNFYSPTEYYEGEWYADKRSGWGRMYYSDGAVYEGEWYDDKQNGEGMLRLANENRYEGEWKDGLKHGKG-----------------IFY-----FLDKGQKYTGVWALDIP 191
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Nematostella
Match: EDO27248 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9S6]) HSP 1 Score: 83.1889 bits (204), Expect = 8.903e-19 Identity = 63/171 (36.84%), Postives = 89/171 (52.05%), Query Frame = 1
Query: 166 KYEGEWQK-GKKHGHGRFVMADGSFYEGEFQNGEICGKG-ERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLW 669
+YEGE G++HG+G ++ G Y+G + NG+ G G R+ K Y GE+ N + GTG M++ +G Y G+W +N R GNG+ YANGD YEGE+ + HG+G+ + G Y G W G G G++ P VY G F G G G TG +
Sbjct: 2 RYEGERNNDGERHGYGTALLTSGDTYQGLYNNGKRHGYGIYRFVNKA--RYEGEYVNNKREGTGTMYFPDGSMYKGEWKNNKRSGNGKYKYANGDTYEGEWKLGRRHGQGVYVYKDLGISYKGNWAFGKFDGKGQVHTPY-YVYNGTFYDETPRGPGRFSFKTGCAQTGQY 169 HSP 2 Score: 74.7146 bits (182), Expect = 8.134e-16 Identity = 55/169 (32.54%), Postives = 84/169 (49.70%), Query Frame = 1
Query: 238 YEGEFQN-GEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD-GSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQ 738
YEGE N GE G G +G+ Y+G ++NG+ G GI + N Y G++++N REG G + + +G +Y+GE+ +K G G + NG Y G W G +HG G D G Y+G + + F G+G + H +Y G + P + P + T Q
Sbjct: 3 YEGERNNDGERHGYGTALLT-SGDTYQGLYNNGKRHGYGIYRFVNKARYEGEYVNNKREGTGTMYFPDGSMYKGEWKNNKRSGNGKYKYANGDTYEGEWKLGRRHGQGVYVYKDLGISYKGNWAFGKFDGKGQV-HTPYYVYNGTFYDETP-RGPGRFSFKTGCAQTGQ 168 HSP 3 Score: 60.8474 bits (146), Expect = 4.781e-11 Identity = 50/144 (34.72%), Postives = 70/144 (48.61%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN-GDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSG 525
Y G N R G+G+Y + NK +YEGE+ K+ G G DGS Y+GE++N + G G +Y G+ Y GE+ G G G+ Y + G Y G+W +G GQ+ + VY G FY G G G +G
Sbjct: 27 YQGLYNNGKRHGYGIYRFVNKA-RYEGEYVNNKREGTGTMYFPDGSMYKGEWKNNKRSGNG-KYKYANGDTYEGEWKLGRRHGQGVYVYKDLGISYKGNWAFGKFDGKGQV-HTPYYVYNGTFYDETPRGPGRFSFKTGCAQTG 167
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Medaka
Match: rsph10b (radial spoke head 10 homolog B [Source:NCBI gene;Acc:101169070]) HSP 1 Score: 106.301 bits (264), Expect = 9.701e-24 Identity = 70/205 (34.15%), Postives = 102/205 (49.76%), Query Frame = 1
Query: 103 GETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE--YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGK---MTMPDGSV-------YEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
G +K L +G+G++ + N YEGE+ + G G+F DGS Y G +G G G KTG Y GE+ G+ G G ++Y Y GDW+ N+REG G+ Y +G+ Y GE+ + HGEG M+ + G Y G W G +HG G + +G + Y G F + HG G ++ G +Y G W+ N
Sbjct: 60 GMFSKGLMDGWGIFTHLNGL-TYEGEFVRNIPTGRGKFTWPDGSTYSGGVVDGVRHGFGTHICAKTGVSYTGEWSRGKRHGEGTVYYNESKTSWYKGDWVMNNREGRGERCYVSGNTYSGEWKCNVRHGEGTMKWLKLGQQYVGRWCEGLQHGKGTHVWIQKREGGLQYFQNNQYHGDFLHGQRHGHGVFYYAGGAIYEGEWKNN 263 HSP 2 Score: 90.1225 bits (222), Expect = 1.366e-18 Identity = 58/181 (32.04%), Postives = 87/181 (48.07%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGR--FVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGN-GDEYHGDWISNSREGNGQ----------LTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQF 600
Y G +R GFG ++ Y GEW +GK+HG G + + S+Y+G++ G+GER + +GN Y GE+ G G M + G +Y G W + G G L Y + Y G+F + HG G+ G+IY G W KHG GK+T +G +++G+F
Sbjct: 104 YSGGVVDGVRHGFGTHICAKTGVSYTGEWSRGKRHGEGTVYYNESKTSWYKGDWVMNNREGRGERCYV-SGNTYSGEWKCNVRHGEGTMKWLKLGQQYVGRWCEGLQHGKGTHVWIQKREGGLQYFQNNQYHGDFLHGQRHGHGVFYYAGGAIYEGEWKNNKKHGQGKLTSKNGHIFKGEF 283 HSP 3 Score: 80.1073 bits (196), Expect = 2.089e-15 Identity = 57/173 (32.95%), Postives = 81/173 (46.82%), Query Frame = 1
Query: 97 YIGETNKMLREGFG-VYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGI----------MFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGS 582
Y GE ++ R G G VY E+K Y+G+W + G G G+ Y GE++ G+G W K G Y G + G G G + Y ++YHGD++ R G+G YA G +YEGE+ +K HG+G + NG I+ G + KM PD S
Sbjct: 128 YTGEWSRGKRHGEGTVYYNESKTSWYKGDWVMNNREGRGERCYVSGNTYSGEWKCNVRHGEGTMKWLKLGQQYVGRWCEGLQHGKGTHVWIQKREGGLQYFQNNQYHGDFLHGQRHGHGVFYYAGGAIYEGEWKNNKKHGQGKLTSKNGHIFKG------EFKDDKMMTPDLS 294 HSP 4 Score: 69.707 bits (169), Expect = 4.380e-12 Identity = 51/167 (30.54%), Postives = 77/167 (46.11%), Query Frame = 1
Query: 262 EICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYE------------------------GEFYKHKIHGEGIMRL--MNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLWEQNL 681
E G+ E Y+ + G+V++G F G M G GI + NG Y G+++ N G G+ T+ +G Y GE+ + K HGEG + S Y G W+ N+ G G+ G+ Y G++ N+ HGEGT+ + G Y G W + L
Sbjct: 43 EFSGQREVYF-EGGHVHKGMFSKGLMDGWGIFTHLNGLTYEGEFVRNIPTGRGKFTWPDGSTYSGGVVDGVRHGFGTHICAKTGVSYTGEWSRGKRHGEGTVYYNESKTSWYKGDWVMNNREGRGERCYVSGNTYSGEWKCNVRHGEGTMKWLKLGQQYVGRWCEGL 208 HSP 5 Score: 60.8474 bits (146), Expect = 2.313e-9 Identity = 41/129 (31.78%), Postives = 60/129 (46.51%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKI 477
N Y GE +R G G + +Y G W +G +HG G V EG Q + N Y G+F +G+ G G+ +Y G Y G+W +N + G G+LT NG +++GEF K+
Sbjct: 174 NTYSGEWKCNVRHGEGTMKWLKLGQQYVGRWCEGLQHGKGTHVWIQKR--EGGLQYFQ------------NNQYHGDFLHGQRHGHGVFYYAGGAIYEGEWKNNKKHGQGKLTSKNGHIFKGEFKDDKM 288 HSP 6 Score: 50.8322 bits (120), Expect = 3.243e-6 Identity = 35/110 (31.82%), Postives = 55/110 (50.00%), Query Frame = 1
Query: 313 RGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGK-MTMPDGSVYEGQFNYNLFHGEGTLFH 639
R E E +G +++ G + G + +G G T+ NG YEGEF ++ G G +GS YSG + G +HG G + G Y G+++ HGEGT+++
Sbjct: 36 REESCEDEFSGQREVYFEGGHVHKGMFSKGLMDGWGIFTHLNGLTYEGEFVRNIPTGRGKFTWPDGSTYSGGVVDGVRHGFGTHICAKTGVSYTGEWSRGKRHGEGTVYY 145
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Medaka
Match: RSPH1 (radial spoke head component 1 [Source:NCBI gene;Acc:101161589]) HSP 1 Score: 93.5893 bits (231), Expect = 1.378e-21 Identity = 64/175 (36.57%), Postives = 93/175 (53.14%), Query Frame = 1
Query: 157 KFFKYEGEWQ-KGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRL-MNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQ 675
K YEG+ G++HG GR V+ +G Y+G +++GE G+G Y K G VY GE+ G G +Y +G +Y G W+++ R+G G TY+NGD YEGE+ H HG+G+ + GS Y G W+ GN G+ + Y+G F N G G G G ++Q
Sbjct: 15 KLANYEGDRNDAGQRHGVGRSVLPNGDIYQGRYEHGERHGQGT-YRFKNGAVYVGEYFKNLKHGQGTFYYPDGSKYEGSWVNDLRQGRGVYTYSNGDTYEGEWLNHFRHGQGVYHYHLTGSKYVGSWVNGNMQSAGEYIHAN-HKYQGNFFNNKPDGPGKFVFDFGCEQHGEFQQ 187 HSP 2 Score: 52.7582 bits (125), Expect = 1.700e-7 Identity = 28/68 (41.18%), Postives = 38/68 (55.88%), Query Frame = 1
Query: 478 HGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNL 681
HG G L NG IY G + G +HG G +G+VY G++ NL HG+GT ++ G Y G W +L
Sbjct: 30 HGVGRSVLPNGDIYQGRYEHGERHGQGTYRFKNGAVYVGEYFKNLKHGQGTFYYPDGSKYEGSWVNDL 97
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Medaka
Match: ENSORLT00000030376.1 (MORN repeat containing 3 [Source:NCBI gene;Acc:101168558]) HSP 1 Score: 90.5077 bits (223), Expect = 3.506e-20 Identity = 62/153 (40.52%), Postives = 85/153 (55.56%), Query Frame = 1
Query: 121 LREGFGVYVYENKFFKYEGEWQKGKKHGHG-RFVMADGSFYEGEFQNGEICGKGERYW--PKT-GNVYR--GEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGK 561
L+ GF V+ KY GEWQ +KHG G + G+ Y GE++ G+ G G Y P++ G V++ GE+ NG+ G GI FY N Y G+W R G G++ + N D+YEGE+ K HGEG + NGS Y G W G ++G GK
Sbjct: 22 LKSGFRHTVFSLNGDKYTGEWQDNRKHGIGIQMWKNTGAVYNGEWRFGKYDGYGTYYVLDPESKGYVWKYDGEWKNGKKHGYGIYFYNNTAVYEGEWSEGQRSGRGKMFHENRDIYEGEWMCDKEHGEGKLLYANGSWYEGSWKDGKRNGSGK 174 HSP 2 Score: 85.8853 bits (211), Expect = 1.526e-18 Identity = 56/155 (36.13%), Postives = 83/155 (53.55%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSF------YEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEG-IMRLMNGSIYSGYWICG 540
Y GE + G G+ +++N Y GEW+ GK G+G + + D Y+GE++NG+ G G ++ T VY GE+ G+ +G G MF+ N D Y G+W+ + G G+L YANG YEG + K +G G G +Y G+WI G
Sbjct: 38 YTGEWQDNRKHGIGIQMWKNTGAVYNGEWRFGKYDGYGTYYVLDPESKGYVWKYDGEWKNGKKHGYGIYFYNNTA-VYEGEWSEGQRSGRGKMFHENRDIYEGEWMCDKEHGEGKLLYANGSWYEGSWKDGKRNGSGKCYNSEKGLLYVGFWIDG 191 HSP 3 Score: 67.0106 bits (162), Expect = 3.627e-12 Identity = 47/149 (31.54%), Postives = 68/149 (45.64%), Query Frame = 1
Query: 226 DGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWE 672
+G Y GE+Q+ G G + W TG VY GE+ G+ G G + + + W Y+GE+ K HG GI N ++Y G W G + G GKM + +YEG++ + HGEG L + G Y G W+
Sbjct: 34 NGDKYTGEWQDNRKHGIGIQMWKNTGAVYNGEWRFGKYDGYGTYYVLDPESKGYVW-----------------KYDGEWKNGKKHGYGIYFYNNTAVYEGEWSEGQRSGRGKMFHENRDIYEGEWMCDKEHGEGKLLYANGSWYEGSWK 165 HSP 4 Score: 51.9878 bits (123), Expect = 4.882e-7 Identity = 32/80 (40.00%), Postives = 50/80 (62.50%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGE 336
Y GE ++ R G G +EN+ YEGEW K+HG G+ + A+GS+YEG +++G+ G G+ Y + G +Y G + +GE
Sbjct: 114 YEGEWSEGQRSGRGKMFHENRDI-YEGEWMCDKEHGEGKLLYANGSWYEGSWKDGKRNGSGKCYNSEKGLLYVGFWIDGE 192
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Medaka
Match: ENSORLT00000010654.2 (MORN repeat containing 3 [Source:NCBI gene;Acc:101168558]) HSP 1 Score: 89.7373 bits (221), Expect = 6.446e-20 Identity = 61/153 (39.87%), Postives = 82/153 (53.59%), Query Frame = 1
Query: 121 LREGFGVYVYENKFFKYEGEWQKGKKHGHG-RFVMADGSFYEGEFQNGEICGKGERYW--PKTGNV---YRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGK 561
L+ GF V+ KY GEWQ +KHG G + G+ Y GE++ G+ G G Y P++ Y GE+ NG+ G GI FY N Y G+W R G G++ + N D+YEGE+ K HGEG + NGS Y G W G ++G GK
Sbjct: 16 LKSGFRHTVFSLNGDKYTGEWQDNRKHGIGIQMWKNTGAVYNGEWRFGKYDGYGTYYVLDPESKGYVWKYDGEWKNGKKHGYGIYFYNNTAVYEGEWSEGQRSGRGKMFHENRDIYEGEWMCDKEHGEGKLLYANGSWYEGSWKDGKRNGSGK 168 HSP 2 Score: 85.5001 bits (210), Expect = 1.935e-18 Identity = 56/155 (36.13%), Postives = 83/155 (53.55%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSF------YEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEG-IMRLMNGSIYSGYWICG 540
Y GE + G G+ +++N Y GEW+ GK G+G + + D Y+GE++NG+ G G ++ T VY GE+ G+ +G G MF+ N D Y G+W+ + G G+L YANG YEG + K +G G G +Y G+WI G
Sbjct: 32 YTGEWQDNRKHGIGIQMWKNTGAVYNGEWRFGKYDGYGTYYVLDPESKGYVWKYDGEWKNGKKHGYGIYFYNNTA-VYEGEWSEGQRSGRGKMFHENRDIYEGEWMCDKEHGEGKLLYANGSWYEGSWKDGKRNGSGKCYNSEKGLLYVGFWIDG 185 HSP 3 Score: 65.855 bits (159), Expect = 8.580e-12 Identity = 47/149 (31.54%), Postives = 68/149 (45.64%), Query Frame = 1
Query: 226 DGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWE 672
+G Y GE+Q+ G G + W TG VY GE+ G+ G G + + + W Y+GE+ K HG GI N ++Y G W G + G GKM + +YEG++ + HGEG L + G Y G W+
Sbjct: 28 NGDKYTGEWQDNRKHGIGIQMWKNTGAVYNGEWRFGKYDGYGTYYVLDPESKGYVW-----------------KYDGEWKNGKKHGYGIYFYNNTAVYEGEWSEGQRSGRGKMFHENRDIYEGEWMCDKEHGEGKLLYANGSWYEGSWK 159 HSP 4 Score: 51.6026 bits (122), Expect = 5.802e-7 Identity = 32/80 (40.00%), Postives = 50/80 (62.50%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGE 336
Y GE ++ R G G +EN+ YEGEW K+HG G+ + A+GS+YEG +++G+ G G+ Y + G +Y G + +GE
Sbjct: 108 YEGEWSEGQRSGRGKMFHENRDI-YEGEWMCDKEHGEGKLLYANGSWYEGSWKDGKRNGSGKCYNSEKGLLYVGFWIDGE 186
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Medaka
Match: als2b (alsin Rho guanine nucleotide exchange factor ALS2 [Source:NCBI gene;Acc:101169837]) HSP 1 Score: 77.411 bits (189), Expect = 2.194e-14 Identity = 55/184 (29.89%), Postives = 86/184 (46.74%), Query Frame = 1
Query: 91 NFYIGETNKMLREGFGVYVYENKFFK----YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPK----TGNVYRGEFHNGEMTGTGIM-FYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSG----YWICGNKHGHGKMTMPDGSVYEGQFN 603
Y G L +GFG ++ NK Y+G W+ GK HG G + A G Y+G FQ+G G G K + +V+ G++ + TG G+ G+++ G W + R+G G + G YEG F +K+ G G++ + + Y G W G G +T+ +G EG F+
Sbjct: 936 RIYTGTFKNGLEDGFGEFLAPNKPLNKNDCYQGHWKDGKMHGPGTYRYASGEVYDGSFQDGVRHGHGMLRSGKLNTSSPSVFIGQWLQDKKTGYGVFDDITKGEKFMGMWQDHLRQGTGVVVTQFGLYYEGAFKDNKMAGTGVLVSEDDTTYEGDFSDDWTLS---GKGVLTLANGDYLEGSFS 1116 HSP 2 Score: 77.0258 bits (188), Expect = 2.921e-14 Identity = 53/166 (31.93%), Postives = 75/166 (45.18%), Query Frame = 1
Query: 169 YEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWP----KTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREG-----NGQLTYANGDVYEGEFYKHKIHGEGIM-RLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLF 636
YEG W GK HG G DG Y G F+NG G GE P + Y+G + +G+M G G Y +G+ Y G + R G +G+L ++ V+ G++ + K G G+ + G + G W + G G + G YEG F N G G L
Sbjct: 915 YEGGWVSGKPHGSGVLKWPDGRIYTGTFKNGLEDGFGEFLAPNKPLNKNDCYQGHWKDGKMHGPGTYRYASGEVYDGSFQDGVRHGHGMLRSGKLNTSSPSVFIGQWLQDKKTGYGVFDDITKGEKFMGMWQDHLRQGTGVVVTQFGLYYEGAFKDNKMAGTGVLV 1080
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Planmine SMEST
Match: SMESG000012434.1 (SMESG000012434.1) HSP 1 Score: 1017.3 bits (2629), Expect = 0.000e+0 Identity = 495/499 (99.20%), Postives = 496/499 (99.40%), Query Frame = 1
Query: 70 MEIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSLFELIEQIDSKPVETTYYPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTETDLTDAPLCNDLCLDPVIQETKNGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQIHPFPISDSLQESTSKNSQKRRRSEYGVKNQIVELPNISQITNXXXXXXXDLF 1566
MEIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGN+YRGEFHNGEMTGTG MFYGNGDEYHGDW SNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSLFELIEQIDSKPVETTYYPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTETDLTDAPLCNDLCLDPVIQETKNGSVDFINLFIQQPK AAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQIHPFPISDSLQESTSKNSQKRRRSEYGVKNQIVELPNISQITNSSSRRSSDLF
Sbjct: 1 MEIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNMYRGEFHNGEMTGTGFMFYGNGDEYHGDWNSNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSLFELIEQIDSKPVETTYYPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTETDLTDAPLCNDLCLDPVIQETKNGSVDFINLFIQQPKFAAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQIHPFPISDSLQESTSKNSQKRRRSEYGVKNQIVELPNISQITNSSSRRSSDLF 499
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Planmine SMEST
Match: SMESG000012434.1 (SMESG000012434.1) HSP 1 Score: 983.786 bits (2542), Expect = 0.000e+0 Identity = 479/483 (99.17%), Postives = 480/483 (99.38%), Query Frame = 1
Query: 118 MLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSLFELIEQIDSKPVETTYYPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTETDLTDAPLCNDLCLDPVIQETKNGSVDFINLFIQQPKLAAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQIHPFPISDSLQESTSKNSQKRRRSEYGVKNQIVELPNISQITNXXXXXXXDLF 1566
MLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGN+YRGEFHNGEMTGTG MFYGNGDEYHGDW SNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSLFELIEQIDSKPVETTYYPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTETDLTDAPLCNDLCLDPVIQETKNGSVDFINLFIQQPK AAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQIHPFPISDSLQESTSKNSQKRRRSEYGVKNQIVELPNISQITNSSSRRSSDLF
Sbjct: 1 MLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNMYRGEFHNGEMTGTGFMFYGNGDEYHGDWNSNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPCKIPTKMKLTTDILDCFQGHTFQISLTLITDNGEIVHEESGRHLRMTAGVKYQPVNDNNSLFELIEQIDSKPVETTYYPVLLVPLTDKPPQWVQSLENASHNKIRLPHLFESDESNSQPPESTETDLTDAPLCNDLCLDPVIQETKNGSVDFINLFIQQPKFAAGSCLQSDSASEFINSASVSATSIKQNKDQSLSEKNIKHKELGDEKFTKLGEYVLIIEDITENPFMENRLETLYTKIQIHPFPISDSLQESTSKNSQKRRRSEYGVKNQIVELPNISQITNSSSRRSSDLF 483
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Planmine SMEST
Match: SMESG000014300.1 (SMESG000014300.1) HSP 1 Score: 91.6633 bits (226), Expect = 4.705e-20 Identity = 63/177 (35.59%), Postives = 92/177 (51.98%), Query Frame = 1
Query: 175 GEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGI-MRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGT-LFHICGILYTGLWEQNLPCKIPT 699
G +K ++HG G+ + +G YEG ++NG+ G G Y K G Y GE+ + G GI FY +G +Y G WI + R GNG+ Y NGD +EGE+ H HG+G GS Y G W G +G+G++ + Y GQ+ + +G+G +F TG + IPT
Sbjct: 23 GRNEKDERHGSGKATLPNGDTYEGLYENGKRHGHG-TYRFKNGARYIGEYSENKKHGHGIFFYPDGSKYEGSWIDDQRNGNGKYYYINGDYFEGEWKNHLRHGQGTYFYDATGSKYVGVWKEGKMNGYGELVHSN-HKYVGQWKNGVMNGKGKYVFDHVKCQLTGEY-----APIPT 192 HSP 2 Score: 77.7962 bits (190), Expect = 1.671e-15 Identity = 47/129 (36.43%), Postives = 71/129 (55.04%), Query Frame = 1
Query: 307 VYRGEFHNG-----EMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFH-ICGILYTGLWEQ 675
+Y GE+ G E G+G NGD Y G + + R G+G + NG Y GE+ ++K HG GI +GS Y G WI ++G+GK +G +EG++ +L HG+GT F+ G Y G+W++
Sbjct: 15 LYLGEYEGGRNEKDERHGSGKATLPNGDTYEGLYENGKRHGHGTYRFKNGARYIGEYSENKKHGHGIFFYPDGSKYEGSWIDDQRNGNGKYYYINGDYFEGEWKNHLRHGQGTYFYDATGSKYVGVWKE 143 HSP 3 Score: 58.151 bits (139), Expect = 5.090e-9 Identity = 35/112 (31.25%), Postives = 64/112 (57.14%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTY 432
YIGE ++ + G G++ Y + KYEG W +++G+G++ +G ++EGE++N G+G ++ TG+ Y G + G+M G G + + N +Y G W + G G+ +
Sbjct: 67 YIGEYSENKKHGHGIFFYPDG-SKYEGSWIDDQRNGNGKYYYINGDYFEGEWKNHLRHGQGTYFYDATGSKYVGVWKEGKMNGYGELVHSN-HKYVGQWKNGVMNGKGKYVF 176
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Planmine SMEST
Match: SMESG000039153.1 (SMESG000039153.1) HSP 1 Score: 93.9745 bits (232), Expect = 5.622e-20 Identity = 57/142 (40.14%), Postives = 76/142 (53.52%), Query Frame = 1
Query: 82 DRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMAD-GSFYEGEFQNGEICGKGERYWP---------KTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKI 477
D+ +FY G+ NK + EGFG Y + YEGEW +GK+HGHG D Y G+++NG G G+ W NVY GEF NG+ G G Y +G Y G W+SN + G G+ + NG +YEGEF +I
Sbjct: 203 DQRSFYEGDWNKNVIEGFGFRQYRSGN-TYEGEWYQGKRHGHGVMKWLDRNEQYTGQWRNGIQNGMGQHIWYVQRINGSQYSLRNVYEGEFCNGKRHGWGCFTYPSGAHYEGFWVSNRKSGKGEFVFKNGRIYEGEFEDDRI 343 HSP 2 Score: 89.3521 bits (220), Expect = 1.387e-18 Identity = 60/181 (33.15%), Postives = 92/181 (50.83%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHG--RFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIM-FYGNGDEYHGDWISNSREGNGQLT----------YANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQF 600
Y G+ +R G G+Y + + Y G W G +HG+G + SFYEG++ I G G R + ++GN Y GE++ G+ G G+M + ++Y G W + + G GQ Y+ +VYEGEF K HG G +G+ Y G+W+ K G G+ +G +YEG+F
Sbjct: 160 YEGDVVHGVRHGRGIYKHPSGMM-YSGLWVNGNRHGNGTVNYDTDQRSFYEGDWNKNVIEGFGFRQY-RSGNTYEGEWYQGKRHGHGVMKWLDRNEQYTGQWRNGIQNGMGQHIWYVQRINGSQYSLRNVYEGEFCNGKRHGWGCFTYPSGAHYEGFWVSNRKSGKGEFVFKNGRIYEGEF 338 HSP 3 Score: 85.8853 bits (211), Expect = 2.098e-17 Identity = 66/196 (33.67%), Postives = 98/196 (50.00%), Query Frame = 1
Query: 130 GFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE--YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGK----MTMPDGS------VYEGQFNYNLFHGEGTLFHICGILYTGLWEQN 678
G G + +++ YEG++ + G G++ DGS YEG+ +G G+G P +G +Y G + NG G G + Y Y GDW N EG G Y +G+ YEGE+Y+ K HG G+M+ ++ Y+G W G ++G G+ + +GS VYEG+F HG G + G Y G W N
Sbjct: 124 GTGRFNWKSTNTSYEGDFLYNEISGKGKYTWQDGSSYEGDVVHGVRHGRGIYKHP-SGMMYSGLWVNGNRHGNGTVNYDTDQRSFYEGDWNKNVIEGFGFRQYRSGNTYEGEWYQGKRHGHGVMKWLDRNEQYTGQWRNGIQNGMGQHIWYVQRINGSQYSLRNVYEGEFCNGKRHGWGCFTYPSGAHYEGFWVSN 318 HSP 4 Score: 62.7734 bits (151), Expect = 3.906e-10 Identity = 45/148 (30.41%), Postives = 67/148 (45.27%), Query Frame = 1
Query: 310 YRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDV-YEGEFYKHKI-----------------------HGEGIMRLMNGSIYSGYWICGNKHGHGKMT--MPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQ 675
Y GE NG G G F+ NG+ + G + + G G+ + + + YEG+F ++I HG GI + +G +YSG W+ GN+HG+G + S YEG +N N+ G G + G Y G W Q
Sbjct: 90 YDGEKSNGRFEGLGTAFFVNGNIFEGMFCEGTMHGTGRFNWKSTNTSYEGDFLYNEISGKGKYTWQDGSSYEGDVVHGVRHGRGIYKHPSGMMYSGLWVNGNRHGNGTVNYDTDQRSFYEGDWNKNVIEGFGFRQYRSGNTYEGEWYQ 237 HSP 5 Score: 57.7658 bits (138), Expect = 1.557e-8 Identity = 34/100 (34.00%), Postives = 52/100 (52.00%), Query Frame = 1
Query: 373 DEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMN-GSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLW 669
+ Y G+ + EG G + NG+++EG F + +HG G + + Y G ++ G GK T DGS YEG + + HG G H G++Y+GLW
Sbjct: 88 ERYDGEKSNGRFEGLGTAFFVNGNIFEGMFCEGTMHGTGRFNWKSTNTSYEGDFLYNEISGKGKYTWQDGSSYEGDVVHGVRHGRGIYKHPSGMMYSGLW 187
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Planmine SMEST
Match: SMESG000011788.1 (SMESG000011788.1) HSP 1 Score: 80.4925 bits (197), Expect = 8.653e-17 Identity = 55/181 (30.39%), Postives = 92/181 (50.83%), Query Frame = 1
Query: 157 KFFKYEGEWQKGKKHGHGRFVMADGSFYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDE-----YHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHI-CGILYTGLWEQNL 681
K F Y+ + + KK H +G Y G++ N G+G Y G +Y G++ + + G G++ G + Y G W +N R G G+ Y++ + YEGE+Y+ K +G G M +G++Y G W G G + +G+ YEGQ+ + +GEG ++I G + G+W N+
Sbjct: 16 KPFWYDADKKANKKGLHHTIYFVNGDQYVGDWNNNMKNGRGTMYLTSQGLMYEGDWKDDKKNGFGVLSVKKGKDTYEKIYSGGWKNNLRHGFGENWYSSNEFYEGEWYEGKRNGWGRMYEADGNVYEGEWENDQMCGQGMLRNKNGNRYEGQWKNGMRNGEGKYYYIDKGQMLKGIWVNNV 196 HSP 2 Score: 70.4774 bits (171), Expect = 1.912e-13 Identity = 48/161 (29.81%), Postives = 77/161 (47.83%), Query Frame = 1
Query: 97 YIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVMADGS-FYEGEFQNGEICGKGERYWPKTGNVYRGEFHNGEMTGTGIMFYGNGDEYHGDWISNSREGNGQLTYANGDVYEGEFYKHKIHGEGIMRLMNGSIYSGYWICGNKHGHGKMTMPD 576
Y+G+ N ++ G G ++ YEG+W+ KK+G G + G YE +Y G + N G G +Y + + Y G+W R G G++ A+G+VYEGE+ ++ G+G++R NG+ Y G W G ++G GK D
Sbjct: 43 YVGDWNNNMKNGRGTMYLTSQGLMYEGDWKDDKKNGFGVLSVKKGKDTYE--------------------KIYSGGWKNNLRHGFGENWYSSNEFYEGEWYEGKRNGWGRMYEADGNVYEGEWENDQMCGQGMLRNKNGNRYEGQWKNGMRNGEGKYYYID 183 HSP 3 Score: 60.077 bits (144), Expect = 6.343e-10 Identity = 37/118 (31.36%), Postives = 61/118 (51.69%), Query Frame = 1
Query: 352 IMFYGNGDEYHGDWISNSREGNGQLTY-ANGDVYEGEFYKHKIHGEGIMRLMNGS-----IYSGYWICGNKHGHGKMTMPDGSVYEGQFNYNLFHGEGTLFHICGILYTGLWEQNLPC 687
+++ NGD+Y GDW +N + G G + + G +YEG++ K +G G++ + G IYSG W +HG G+ YEG++ +G G ++ G +Y G WE + C
Sbjct: 34 TIYFVNGDQYVGDWNNNMKNGRGTMYLTSQGLMYEGDWKDDKKNGFGVLSVKKGKDTYEKIYSGGWKNNLRHGFGENWYSSNEFYEGEWYEGKRNGWGRMYEADGNVYEGEWENDQMC 151 The following BLAST results are available for this feature:
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Phosphatidylinositol 4-phosphate 5-kinase 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031461 ID=SMED30031461|Name=Phosphatidylinositol 4-phosphate 5-kinase 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1608bpback to top protein sequence of SMED30031461-orf-1 >SMED30031461-orf-1 ID=SMED30031461-orf-1|Name=SMED30031461-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=500bp MEIKDRNNFYIGETNKMLREGFGVYVYENKFFKYEGEWQKGKKHGHGRFVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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