Protocadherin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031442 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 231.491 bits (589), Expect = 7.473e-62 Identity = 179/610 (29.34%), Postives = 292/610 (47.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKT 2255
NDN+P F I EN+ I S +P+A D D P GV SYE++ E +++ + ED + KQP LIV +DRE D + T+ DGG PPR + + VLD ND P+F + YE ++ E+ G ++ ++ D D G N +I F + + ++ +L + + ++ +D E ++ F+++AKD G P+S+ A V V V ++ND+ P I ++ Q I+E ++ + LV+V+D D+ + ++TC + A +T + +++K Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF+ S + N+ E++ I A+D D G N + Y + K F+I TG ++ LD E+ + +++ A D G P + ++VNV D NDN P+ LS Y+F + EN P + VG V V D D N + L Q + F I N +G I + + DRE S F + A +D G + + VT+N+LD+NDN+P + K + P+ +T
Sbjct: 162 NDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAED-QEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAP-EVVRRLLRLDRNTGLITVQ--GPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGL-VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGS--DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIA----EITASDADSGSNAELVYSLEP-EPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ------------LSVEQ-DNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKA-----VDGGVPPRSAY-----VGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGET 735 HSP 2 Score: 141.739 bits (356), Expect = 1.580e-33 Identity = 160/567 (28.22%), Postives = 243/567 (42.86%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDP--------ILATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK--NNDY 2369
++V D ND P F+ + + I E+ G D+D+G NG S + + Q F L Q L ++ LD E + Y + +D G PPR+S+AL+ V V + ND+ P +F +P + ++E + + VK D D A++ EIE + F+ +L +R T I + DRE TL F S++ D G N ++ V +KD+NDNAP R G+V + + I++D + +D+DEGEN V ++ V D K YF ++T LDYEK+K +IEI A D G P SS+ L V V D NDN P S EN G + ++ +D D+ N + + L P P A +FTI E+G+I K LDRE ++A+ D G + +V VN+LD NDN P ML +F + P VT +D D+GEN++V+++++ N D+
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP--EAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAP-----KFERPSYE----AELSENSPIGHSVIQVKANDSDQGANA---EIEYT---FHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRF-SVLAKD-RGTNPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQ--DGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYF--------LQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYS----LEPEPA------AKGLFTISPETGEIQVKTSLDREQRESYELKVVAA-----DRGSPSLQG-----TATVLVNVLDCNDNDPKFMLSG----------YNFSVMENMPALSPVGMVTV----IDGDKGENAQVQLSVEQDNGDF 658 HSP 3 Score: 88.9669 bits (219), Expect = 3.522e-17 Identity = 88/319 (27.59%), Postives = 142/319 (44.51%), Query Frame = 3
Query: 1446 EVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI-------DKNTGVVKTILG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
++ ++DINDN P F+SP + EN I ++ P LA+D+D G NG Y + + + F + +K ++ ++G LD E+ + I +D G P R+SS L V V DTNDN P+ + Y EL EN PIG V +V D D N + + + ++ +D +G I + +DRE S + F+++A D G + + V V + D NDN+P + ++ + V + S E++ E V + D DEGEN+ V + + F L
Sbjct: 155 QIEVQDINDNTPNFASPVITLAIPEN--TNIGSLFPIP-LASDRDAGPNGVASYEL-QAGPEAQELFGLQVAEDQEEKQPQLI--VMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ---------APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK-----DRGTN-----PKSARAQVVVTVKDMNDNAPTIEIRG---IGLVTHQDGMANIS--EDVAEETAVALVQV-SDRDEGENAAVTCVVAGDVPFQL 442 HSP 4 Score: 69.3218 bits (168), Expect = 3.381e-11 Identity = 59/223 (26.46%), Postives = 93/223 (41.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + D D +E+ N +F + N ++ DRE F L AVDGG PPR + + VLDEND P S +++ ++ + G + + ED DSG N ++ + A + FQ+ H A+ L +++ + + D G+PPR TALV ++V
Sbjct: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDF----------VIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRL-GETVSQVAAEDFDSGVNAELIYSIAGGNPYGL---FQIGS--HSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 231.876 bits (590), Expect = 1.052e-61 Identity = 179/610 (29.34%), Postives = 292/610 (47.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKT 2255
NDN+P F I EN+ I S +P+A D D P GV SYE++ E +++ + ED + KQP LIV +DRE D + T+ DGG PPR + + VLD ND P+F + YE ++ E+ G ++ ++ D D G N +I F + + ++ +L + + ++ +D E ++ F+++AKD G P+S+ A V V V ++ND+ P I ++ Q I+E ++ + LV+V+D D+ + ++TC + A +T + +++K Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF+ S + N+ E++ I A+D D G N + Y + K F+I TG ++ LD E+ + +++ A D G P + ++VNV D NDN P+ LS Y+F + EN P + VG V V D D N + L Q + F I N +G I + + DRE S F + A +D G + + VT+N+LD+NDN+P + K + P+ +T
Sbjct: 162 NDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAED-QEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAP-EVVRRLLRLDRNTGLITVQ--GPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGL-VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGS--DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIA----EITASDADSGSNAELVYSL-EPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ------------LSVEQ-DNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKA-----VDGGVPPRSAY-----VGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGET 735 HSP 2 Score: 142.51 bits (358), Expect = 1.172e-33 Identity = 160/567 (28.22%), Postives = 243/567 (42.86%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDP--------ILATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK--NNDY 2369
++V D ND P F+ + + I E+ G D+D+G NG S + + Q F L Q L ++ LD E + Y + +D G PPR+S+AL+ V V + ND+ P +F +P + ++E + + VK D D A++ EIE + F+ +L +R T I + DRE TL F S++ D G N ++ V +KD+NDNAP R G+V + + I++D + +D+DEGEN V ++ V D K YF ++T LDYEK+K +IEI A D G P SS+ L V V D NDN P S EN G + ++ +D D+ N + + L P P A +FTI E+G+I K LDRE ++A+ D G + +V VN+LD NDN P ML +F + P VT +D D+GEN++V+++++ N D+
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP--EAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAP-----KFERPSYE----AELSENSPIGHSVIQVKANDSDQGANA---EIEYT---FHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRF-SVLAKD-RGTNPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQ--DGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYF--------LQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYS----LEPEPA------AKGLFTISPETGEIQVKTSLDREQRESYELKVVAA-----DRGSPSLQG-----TATVLVNVLDCNDNDPKFMLSG----------YNFSVMENMPALSPVGMVTV----IDGDKGENAQVQLSVEQDNGDF 658 HSP 3 Score: 89.3521 bits (220), Expect = 2.659e-17 Identity = 88/319 (27.59%), Postives = 142/319 (44.51%), Query Frame = 3
Query: 1446 EVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI-------DKNTGVVKTILG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
++ ++DINDN P F+SP + EN I ++ P LA+D+D G NG Y + + + F + +K ++ ++G LD E+ + I +D G P R+SS L V V DTNDN P+ + Y EL EN PIG V +V D D N + + + ++ +D +G I + +DRE S + F+++A D G + + V V + D NDN+P + ++ + V + S E++ E V + D DEGEN+ V + + F L
Sbjct: 155 QIEVQDINDNTPNFASPVITLAIPEN--TNIGSLFPIP-LASDRDAGPNGVASYEL-QAGPEAQELFGLQVAEDQEEKQPQLI--VMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ---------APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK-----DRGTN-----PKSARAQVVVTVKDMNDNAPTIEIRG---IGLVTHQDGMANIS--EDVAEETAVALVQV-SDRDEGENAAVTCVVAGDVPFQL 442 HSP 4 Score: 68.9366 bits (167), Expect = 4.437e-11 Identity = 59/223 (26.46%), Postives = 93/223 (41.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + D D +E+ N +F + N ++ DRE F L AVDGG PPR + + VLDEND P S +++ ++ + G + + ED DSG N ++ + A + FQ+ H A+ L +++ + + D G+PPR TALV ++V
Sbjct: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDF----------VIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRL-GETVSQVAAEDFDSGVNAELIYSIAGGNPYGL---FQIGS--HSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 214.927 bits (546), Expect = 2.984e-56 Identity = 209/701 (29.81%), Postives = 316/701 (45.08%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEK--LPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I ENS INS+ +LP A D D GV++YE+ K F + + E +K P LIV+ ++DRE D + DGG P R + + V D ND P F + E+ I E+ G + L D D G N KI +F++ + + F L+ T + +K LD E + ++A D G P + A+V V VT+VND+ P+I P++ + ++E + I L+ VTD D + +TC + + F L + +N L Y D E+ + + ++ +D G L Q+ L + +KD NDNAPVF+ + EN I + + ATD D G N + Y + D FS+D+ TG++ + LD EK I AKD GVP +S+V + V++ D NDN P + Y F + EN P VG + VTD D N+ TL D FTID+++G I + DRE F + A +D R R + VT+N++D NDN P+ + V N + STN V F I VD D G N++VR V D F++ + G + MEK + +G ++ ++ A D +S ++N+ + E
Sbjct: 165 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK--EPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT---VVLSENIPLNTKIALITVTDKDADHNGRVTCFTD-HEIPFRLRPVFSNQFLLENAAY-------LDYESTKEYAIKLLAADA-GKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK---VSATDADSGPNAEINYLLG---PDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------------TLSILDENDD-FTIDSQTGVIRPNISFDREKQESYTFYVKA---------EDGGRVSRSS-SAKVTINVVDVNDNKPVFI------VPPYNYSYELVLPSTN-----PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNE 806 HSP 2 Score: 73.9442 bits (180), Expect = 1.623e-12 Identity = 79/267 (29.59%), Postives = 118/267 (44.19%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
K+ +I+DINDNAP+F + + EN +N T+ A D D G NG Y + +N F +D V++T G LD E+ +++ +D G P RSS+ L V+V DTNDN P + + EN P+GT V +++ TD D N K + S A ++F ++ +G I K LDRE + ++AS D G R V VN+ D NDN P + ++
Sbjct: 156 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA----AVDPDVGINGVQNYELIK----SQNIFGLD----VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLV--------SNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLAS-----DGGLMPARAM-------VLVNVTDVNDNVPSIDIR 390
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 213.001 bits (541), Expect = 6.332e-56 Identity = 209/701 (29.81%), Postives = 316/701 (45.08%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEK--LPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I ENS INS+ +LP A D D GV++YE+ K F + + E +K P LIV+ ++DRE D + DGG P R + + V D ND P F + E+ I E+ G + L D D G N KI +F++ + + F L+ T + +K LD E + ++A D G P + A+V V VT+VND+ P+I P++ + ++E + I L+ VTD D + +TC + + F L + +N L Y D E+ + + ++ +D G L Q+ L + +KD NDNAPVF+ + EN I + + ATD D G N + Y + D FS+D+ TG++ + LD EK I AKD GVP +S+V + V++ D NDN P + Y F + EN P VG + VTD D N+ TL D FTID+++G I + DRE F + A +D R R + VT+N++D NDN P+ + V N + STN V F I VD D G N++VR V D F++ + G + MEK + +G ++ ++ A D +S ++N+ + E
Sbjct: 154 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK--EPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT---VVLSENIPLNTKIALITVTDKDADHNGRVTCFTD-HEIPFRLRPVFSNQFLLENAAY-------LDYESTKEYAIKLLAADA-GKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK---VSATDADSGPNAEINYLLG---PDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------------TLSILDENDD-FTIDSQTGVIRPNISFDREKQESYTFYVKA---------EDGGRVSRSS-SAKVTINVVDVNDNKPVFI------VPPYNYSYELVLPSTN-----PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNE 795 HSP 2 Score: 72.0182 bits (175), Expect = 5.536e-12 Identity = 79/267 (29.59%), Postives = 118/267 (44.19%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
K+ +I+DINDNAP+F + + EN +N T+ A D D G NG Y + +N F +D V++T G LD E+ +++ +D G P RSS+ L V+V DTNDN P + + EN P+GT V +++ TD D N K + S A ++F ++ +G I K LDRE + ++AS D G R V VN+ D NDN P + ++
Sbjct: 145 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA----AVDPDVGINGVQNYELIK----SQNIFGLD----VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLV--------SNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLAS-----DGGLMPARAM-------VLVNVTDVNDNVPSIDIR 379
BLAST of Protocadherin-1 vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 213.001 bits (541), Expect = 6.332e-56 Identity = 209/701 (29.81%), Postives = 316/701 (45.08%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEK--LPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I ENS INS+ +LP A D D GV++YE+ K F + + E +K P LIV+ ++DRE D + DGG P R + + V D ND P F + E+ I E+ G + L D D G N KI +F++ + + F L+ T + +K LD E + ++A D G P + A+V V VT+VND+ P+I P++ + ++E + I L+ VTD D + +TC + + F L + +N L Y D E+ + + ++ +D G L Q+ L + +KD NDNAPVF+ + EN I + + ATD D G N + Y + D FS+D+ TG++ + LD EK I AKD GVP +S+V + V++ D NDN P + Y F + EN P VG + VTD D N+ TL D FTID+++G I + DRE F + A +D R R + VT+N++D NDN P+ + V N + STN V F I VD D G N++VR V D F++ + G + MEK + +G ++ ++ A D +S ++N+ + E
Sbjct: 154 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK--EPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT---VVLSENIPLNTKIALITVTDKDADHNGRVTCFTD-HEIPFRLRPVFSNQFLLENAAY-------LDYESTKEYAIKLLAADA-GKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK---VSATDADSGPNAEINYLLG---PDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------------TLSILDENDD-FTIDSQTGVIRPNISFDREKQESYTFYVKA---------EDGGRVSRSS-SAKVTINVVDVNDNKPVFI------VPPYNYSYELVLPSTN-----PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNE 795 HSP 2 Score: 72.0182 bits (175), Expect = 5.536e-12 Identity = 79/267 (29.59%), Postives = 118/267 (44.19%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
K+ +I+DINDNAP+F + + EN +N T+ A D D G NG Y + +N F +D V++T G LD E+ +++ +D G P RSS+ L V+V DTNDN P + + EN P+GT V +++ TD D N K + S A ++F ++ +G I K LDRE + ++AS D G R V VN+ D NDN P + ++
Sbjct: 145 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA----AVDPDVGINGVQNYELIK----SQNIFGLD----VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLV--------SNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLAS-----DGGLMPARAM-------VLVNVTDVNDNVPSIDIR 379
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 166.007 bits (419), Expect = 4.615e-41 Identity = 181/711 (25.46%), Postives = 298/711 (41.91%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVN-DSPP---------NIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPM-------MMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRV-TMKNNDYFSLTPDYGMLCAMEKLPPIGDYKTVIVAEDGDFNNSRKQEFLINIHI 2510
NDN+P+F ++ EI E +++ + +LP D D F V + I + N N FKL + + Q L+V Q+DREF D+ E + A DGGKP + G+ + ++++D ND P FS+ Y + + G L+ ++ D D G N +IS + ++ N F +SQ+ GV S L T + +VA D G P SS+A+V + V SPP N N + AR+ I + +D + L+ S C +T Q YL L +L DRET + H + + E Q+ + + I DINDNAP + S + + + NR + A D D G+NG + Y +V+D SIDK TG + +D + + A+D G P S+ ++++ ++ DT P+ + + + E+ E+ PIGT + KV + + + + Q D+ T+D SG + + D E +IA+N N +T +++ + D NDN P+ + +++ P+ PE + S + D+D G +V + + FS+ P G + A + L G + V+ A+DG +S NIHI
Sbjct: 116 NDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNN--VFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSN-FAISQS--GVITTTASLLPAST---HDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQ-QYRDTKLRLI--------GSSALCPQQTDQAHVYL--LLLCGIL--------------DRETASEHHLKFLL---EKDGQIIIEHPQLLTIGDINDNAPQWHSSQIH--ISLNRTQG----GSRTLTAKDPDLGQNGWIRY---SVLD--TELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRY-------------SLQNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNAN------------SETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPK-----PEEPLLVVSAS----------------DMDSGTFGEVSYHILSESSSFSINPVTGEVFAQKPLAR-GRFHLVVSAKDGGGQSSENSA---NIHI 729 HSP 2 Score: 112.464 bits (280), Expect = 1.060e-24 Identity = 142/548 (25.91%), Postives = 237/548 (43.25%), Query Frame = 3
Query: 624 VDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLV--AKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTN-AVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKT 2255
VD + ++ D E + T+IA + I LK D ND P F Y + ++E LL + D DSG G++S + S ++ S +++ V ++ ++ + + + F+LV AKD G ++A + + V + + P Q++R TT+D++ + A + + S Y N ++ E+ + +D D L + E NQ ++ + I+D NDN P FSS ++E+ +++E + + A+DKD+ +NG V Y I + + ID+ TG + T LDYE ++ + + A DLG+P RSS++ L ++V D NDN PE + S+Y+ E+ EN P T VGKV DKD+ L G + + F ID + G +YTK +DRE+ S + +I+A D G + S +++LD NDN P + V A +P + I T
Sbjct: 588 VDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSETSTSLISIRLK--DVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESS---------SFSINPVTGEVFAQ---KPLARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTP-------------QFSRSKYEIRTTEDILPGI---------AIGSVGAMSKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGES-NQ----TQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYV----VQASDKDKKKNGEVRYSI--ISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDS-------------LENGQIVYRITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAE-----DKGVP-----PRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTAIGT 1065 HSP 3 Score: 106.686 bits (265), Expect = 6.448e-23 Identity = 129/491 (26.27%), Postives = 208/491 (42.36%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAK-DFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN P F Y+ + E K + + A D D FG SY I + +F + + E F ++P+ R + A DGG + I + V+D++ PQFS+ YEI+ E + G+ + G+ G +S S + D + F + + + + LD + + N+ A G+ S+ V +F+ + ND+PP QF S I I E +V+ +D D + + E+ S +++ +++ ++ T ++ + D E + + + +D GI L + + D+NDNAP F Y V EN + + ++A DKD ENG + Y I+N YF ID+ G V T +D E I HV I I A+D GVP RSS+ ++V D NDN P LS + P+ T +G + D D
Sbjct: 635 NDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSSFSIN-PVTGEVFA--QKPLAR----------GRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAI----------GSVGAMSKVKYSIYSGDQDHNFSIDEDTGKIYVT--RYLDADVHDTVLLNIQATLPSGE---SNQTQVVIFIEDHNDNPP-----QF----SSSLVEISIREDLKLHEPFYVVQASDKDKKKNG---EVRYS----IISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDL-GIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIV---GKVVARDKDSLENGQIVYRITN----GSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSC-LSITPIVVPAGSPLSTAIGTIVAMDPD 1072 HSP 4 Score: 84.7297 bits (208), Expect = 3.802e-16 Identity = 102/398 (25.63%), Postives = 165/398 (41.46%), Query Frame = 3
Query: 738 KTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASS---TNQDI-QNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDN-QADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDP-------ILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNV-KDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVT 1892
+T++++ + D ND PQFS + EI I+E ++ DKD NG++ + SS ++ +I Q T QLS S LDYE Y + A D G PPRSS + + V +VND+ P K + + + E + ++ V D D+ + I I E F + + K + +K DRE + +SIV D +G+ T + + D+NDN P S + IV P I+A D D+G NG+V Y +++ + K+ G V L+ +H + + D GVP +S + V + K + D Q + Y E+ ++ P G + +N T
Sbjct: 820 QTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTG---------SLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPE---------FEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFGI----------DEKLGNVYTKRSIDREVISHVDISIVAED-KGVPPRSSTASARISVLDVNDNPPSCLS-----------ITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRA-----QLQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRISKGSADIQIQEPFQKY-IEIPKSCPTGCRLTTLNAT 1171 HSP 5 Score: 73.9442 bits (180), Expect = 6.888e-13 Identity = 96/421 (22.80%), Postives = 186/421 (44.18%), Query Frame = 3
Query: 444 PTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDI------QNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV--TNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDD-DNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVK 1676
P F + + E++ENSKI +I ++ + Y I+ P ++ F +K L V IDRE EF + + +K + K + VLDEND P F+ + Y + +K+S G ++ + D+DSG NG++S S + +I + QL++ ++LD + + A+D G P R++ V+V + ++ + S P V + +++ E T+ V+ ++ ++ + D + ++ Q ++ KT E+ K D E++ + +S+ S ++G N L+++++ +++ APVF+ Y I E V + A D+D G +G V+Y IS D ++ I+++TG+++
Sbjct: 2129 PGFEKAEFRFEVMENSKIGLQIGNLSGEESREF-----HYRIQDPE---------ASKIFSIDKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWND-------AQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVY---------EVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGKLGIDV----------KTGELTLKTHLDWESEPI--ISMYLSVSDG-NGRSAVVPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESV----GQMQAIDEDGGVHGVVKYSIS----DRQSTVKIEEHTGIIR 2498 HSP 6 Score: 60.4622 bits (145), Expect = 8.361e-9 Identity = 107/470 (22.77%), Postives = 174/470 (37.02%), Query Frame = 3
Query: 663 IDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF-SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPIS--KQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF--SSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYY-ISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYEN--EPI----GTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVV 2036
+DRE +I DGG R + + V D+ND +PQ + E++I ES G L R D D G NGK S +D + L + L+ +S L + L D G P VE + N +P + P+ KQ I+EG + I + E + ++ + ++ I++ ++ DRE + + ++ + G Q T +++V + ++NDN P F S PR RV E + + KD + Y+ +S+ +F+ID+ TG + LD+E + ++ I A D + L + V D NDN P +S LY+ P G K+ D D T Q + IF + ESG ++ KV+
Sbjct: 1687 LDREASQEHLLIIILTDGGS--RNDSCTVRVTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELL----EDSSGSLDLVPETGDLVLRRLSSL-----QSWKIKLRVVDHGVP----GLYVEKNLEISNRNPQT----EAKAPLEFLKQTYLSTIDEGLPRGQFIA--------------KLQPELAGLTYSIVEGNIDSAFSVDSEGVIRTNLELDREILERYSLKVIGT---GSGQQIGT-RVDVRVNNLNDNVPSFPMSKPR--------RVPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSF---DTFTNLTIFVSDINDNAPT-----FSKPLYQTTVSPATFSPGQPFAKIEAHDLDARGAL--------------TYSLGQGSSSIFRVAPESGALFMKVL 2089
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 144.436 bits (363), Expect = 2.048e-34 Identity = 128/492 (26.02%), Postives = 225/492 (45.73%), Query Frame = 3
Query: 438 NSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD--PILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTD 1907
N+ F ++ Y KE+ E++ I + I+ A A P Y + P ++ L T D + + + + +DRE +D+ + A + P T +++ VLD D P F + Y +I+E G +L + D DSG NG+I + +++ L+ ++ + LD ET++ +++A D G P R STA+VE+ V +VND+ P +N + I E T VI VK TD+D + ++ S S + + + + ++ +ID K +++ + L T L + + DIND+AP + + ++EN V I ++ + A D+D G NG ++Y + D F ID+++G++KT LD E S++++A+D+G P ++S + V +KD NDN P D Y+ + E P G+ + + D D D
Sbjct: 161 NAVHFQQEKYVKELPEDTPIETIIASVKASHASSQPL---YYSMVAPQDSRSQ--NLFTLDTMSGE---IRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNL-----LAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYN---------VTILENITIPAVIATVKATDEDFGTNG---KVHYSMASS--SGIGGLTIDYSTGEVTLRERID----AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEEN-----VAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED-----FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDED 611 HSP 2 Score: 129.028 bits (323), Expect = 8.750e-30 Identity = 157/597 (26.30%), Postives = 252/597 (42.21%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDR----IEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFY--LNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEIS----VTVNILDKNDNSP 2189
NDN+P F +Y ILEN I + I+ A D D FG N V++ + + + RE ID I + A DG +P + + V+D ND P I ++E+ G E+ + D+DSG NG I + S + I L +K LD ET +YS + A+D G P +++ + V + ++ND+ P ++N IS++ R +I L V +D++Q IT IE + + L+ A+L + E+K + D + + V I +D G L+ + V I D+N +AP F+ P I + + + V K A D D G+N + Y I D +F ID ++G + LD E S+ ++A D P ++S ++ V + D NDN P+ S Y+ + E+ P+GT +V+ D D N + +S P+ Q+F +D SG + LDRE FA+I +F + R T +S +T+ + D NDN+P
Sbjct: 369 NDNAPVFASDSYNVTILENITIPAVIATVKATDED---FGT----------NGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGL--------IKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPR--------GSQIITLKAVDNDEDQ--KITYRIEEADREVFSILDIGDQGAILS--VSGELKRQ---DHKVR----VEISATDQGG---LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLK----AEDHDRGDNARIVYSI-----DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNE--------SSSSPSIQLFRLDRTSGTLRVSSKLDREQ-----FAVIV---------LPIFARDRGTPSLSAASEITLTLSDVNDNAP 890 HSP 3 Score: 122.865 bits (307), Expect = 7.542e-28 Identity = 125/493 (25.35%), Postives = 212/493 (43.00%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFV-DNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMK-NYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
ND++PT + EN I + A D D P G+ Y +E +EDF+ D ++ +DRE R + A D G P T I + + D ND P F + Y + I E G +++ L+ D D + KI+ + ++++ + + G L + +L + +K + A D Q +V VF+ +VN +P Y + P S + I E + + +K D D ++ I I++SQ F ++ + +I D DRE + V + SD L + ++EVI+ DINDN+P F+S Y + E+ V + + A D D G NG V+Y+++ F +D+ +G ++ LD E+ + + I A+D G P S++ ++ + + D NDN P + Y + EN P+G+ VG + D D
Sbjct: 473 NDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEG------------SEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEA-DREVFSILDIGD--QGAILSVSGELKRQD-HKVRVEISATD--QGGLQGRCVVNVFIDDVNSAP-----YFNDHPFS-----VKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQ-FFRIDP----------SSGDISVSSDLDREDRATFSVIVTASD-HASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIP---VGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDAD 920 HSP 4 Score: 117.472 bits (293), Expect = 3.518e-26 Identity = 149/596 (25.00%), Postives = 249/596 (41.78%), Query Frame = 3
Query: 435 DNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQF------NKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN--RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNV-KDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN--PLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
DNSP F + +Y+ EI E++ I + + A D D G Y + + N L+ ++ K ++ +DRE + I +IA D G P R+ + + V+D ND P F+ Y + I E+ + ++ D+D G NGK+ + ASS+ + + V L+ ++D + + + + AKD QP SST + + V ++ND P ++ Q N I ++ R+Y D+D+ + I E F + + + IK+ DRET + + + D G L + + V++KDINDNAP F Y + E R ++I+T+ A D DE + + Y I ++ + I + G + ++ G + V +EISA D G + +VNV D ++ P + +S ++ E+ PIG V + D D N + + S + Q F ID SG I LDRE + + AS+ PL+ + +I V ++ D NDNSP
Sbjct: 265 DNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGK-----NLLA---INAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSG---IGGLTIDYSTGEVTLR--ERIDAKN-SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVY---------------AIDEDSGPNGIIKYSMEGSEDFII----------DEDSGLIKTTKLLDRETTARYSLKVTARDM-GTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLK-----AVDNDEDQK--ITYRIEEADREVFSILDIG-DQGAILSVSGELKRQDHKVRVEISATDQG----GLQGRCVVNVFIDDVNSAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNAR--------------IVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLN----------TSTQIEVILD--DINDNSP 782 HSP 5 Score: 95.5153 bits (236), Expect = 1.726e-19 Identity = 122/500 (24.40%), Postives = 216/500 (43.20%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE----NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNT---GVVK--TILGLDYE-KIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN+PTF +K Y I E S+I A D D+ +Y IE+ + F ++ + ++ IL V ++ R+ ++ + A D G +G+ ++ +D+ + P F+ + +KI E G ++ L+ ED D G+N +I + SS F++ + +++ S LD E +S + A D PP +++ +EV + ++ND+ P + IS+ I GT+ V D D + I ++LN ++ ++ +R + ++ DRE + + I D G L +++ + + D+NDNAP F Y + EN V I+A D DEG+N + + I D F I+++ GVV+ T DYE K E+ A + SS+V + ++V D NDN+P + ++N + +G + D D
Sbjct: 575 NDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADREV---FSILD---IGDQGAILSVSGELKRQ-DHKVRVEISATDQGG--LQGRC-VVNVFIDDVNSAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS------QFFRIDPSSGDISVS--SDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISED-----IPVGTS----FLQVSAIDADIGPNGIV--------DYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARD-RGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAEN---SPVGSTVGTIVARDADEGDNADISFRIFGGAD--AKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQL---SSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPD 1028 HSP 6 Score: 92.4337 bits (228), Expect = 1.518e-18 Identity = 86/356 (24.16%), Postives = 156/356 (43.82%), Query Frame = 3
Query: 1335 EIKSKIDFDRETKTLHFVSIVCSDTEGIN-QLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGML 2399
EI+ DRE H + + + E ++ + + + V + D+ DN+P+F Y+G ++E+ ++ + A D D GENG +EY + + KN +I+ +GV++T LD E + + +++ A D G P R S+ + + V D NDN P Y+ + EN I + V TD+D N K S TID +G++ + +D + +S I I A + Q + + +T+N++D ND++P ++ K + EN+ V Y +D D G N ++ +M+ ++ F + D G++
Sbjct: 221 EIRLAKSMDREVLDKHILKV--TAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLS---VFARDLDSGENGEIEYSLGE--GNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSM-----------ASSSGIGGLTIDYSTGEVTLRERIDAK-NSPITAVIRAKDG----------AQPALSSTVPLTINVIDINDHAPTLIAAQK-------------MITLEENVAIGEEVGRVYA-IDEDSGPNGIIKYSMEGSEDFIIDEDSGLI 533
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 128.642 bits (322), Expect = 1.175e-29 Identity = 157/597 (26.30%), Postives = 252/597 (42.21%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDR----IEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFY--LNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEIS----VTVNILDKNDNSP 2189
NDN+P F +Y ILEN I + I+ A D D FG N V++ + + + RE ID I + A DG +P + + V+D ND P I ++E+ G E+ + D+DSG NG I + S + I L +K LD ET +YS + A+D G P +++ + V + ++ND+ P ++N IS++ R +I L V +D++Q IT IE + + L+ A+L + E+K + D + + V I +D G L+ + V I D+N +AP F+ P I + + + V K A D D G+N + Y I D +F ID ++G + LD E S+ ++A D P ++S ++ V + D NDN P+ S Y+ + E+ P+GT +V+ D D N + +S P+ Q+F +D SG + LDRE FA+I +F + R T +S +T+ + D NDN+P
Sbjct: 10 NDNAPVFASDSYNVTILENITIPAVIATVKATDED---FGT----------NGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGL--------IKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPR--------GSQIITLKAVDNDEDQ--KITYRIEEADREVFSILDIGDQGAILS--VSGELKRQ---DHKVR----VEISATDQGG---LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLK----AEDHDRGDNARIVYSI-----DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNE--------SSSSPSIQLFRLDRTSGTLRVSSKLDREQ-----FAVIV---------LPIFARDRGTPSLSAASEITLTLSDVNDNAP 531 HSP 2 Score: 122.865 bits (307), Expect = 6.755e-28 Identity = 125/493 (25.35%), Postives = 212/493 (43.00%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFV-DNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMK-NYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
ND++PT + EN I + A D D P G+ Y +E +EDF+ D ++ +DRE R + A D G P T I + + D ND P F + Y + I E G +++ L+ D D + KI+ + ++++ + + G L + +L + +K + A D Q +V VF+ +VN +P Y + P S + I E + + +K D D ++ I I++SQ F ++ + +I D DRE + V + SD L + ++EVI+ DINDN+P F+S Y + E+ V + + A D D G NG V+Y+++ F +D+ +G ++ LD E+ + + I A+D G P S++ ++ + + D NDN P + Y + EN P+G+ VG + D D
Sbjct: 114 NDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEG------------SEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEA-DREVFSILDIGD--QGAILSVSGELKRQD-HKVRVEISATD--QGGLQGRCVVNVFIDDVNSAP-----YFNDHPFS-----VKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQ-FFRIDP----------SSGDISVSSDLDREDRATFSVIVTASD-HASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIP---VGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDAD 561 HSP 3 Score: 95.9005 bits (237), Expect = 1.288e-19 Identity = 122/500 (24.40%), Postives = 216/500 (43.20%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE----NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNT---GVVK--TILGLDYE-KIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN+PTF +K Y I E S+I A D D+ +Y IE+ + F ++ + ++ IL V ++ R+ ++ + A D G +G+ ++ +D+ + P F+ + +KI E G ++ L+ ED D G+N +I + SS F++ + +++ S LD E +S + A D PP +++ +EV + ++ND+ P + IS+ I GT+ V D D + I ++LN ++ ++ +R + ++ DRE + + I D G L +++ + + D+NDNAP F Y + EN V I+A D DEG+N + + I D F I+++ GVV+ T DYE K E+ A + SS+V + ++V D NDN+P + ++N + +G + D D
Sbjct: 216 NDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADREV---FSILD---IGDQGAILSVSGELKRQ-DHKVRVEISATDQGG--LQGRC-VVNVFIDDVNSAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS------QFFRIDPSSGDISVS--SDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISED-----IPVGTS----FLQVSAIDADIGPNGIV--------DYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARD-RGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAEN---SPVGSTVGTIVARDADEGDNADISFRIFGGAD--AKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQL---SSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPD 669 HSP 4 Score: 83.1889 bits (204), Expect = 8.615e-16 Identity = 74/280 (26.43%), Postives = 129/280 (46.07%), Query Frame = 3
Query: 1074 LVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD--PILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTD 1907
+VE+ V +VND+ P +N + I E T VI VK TD+D + ++ S S + + + + ++ +ID K +++ + L T L + + DIND+AP + + ++EN V I ++ + A D+D G NG ++Y + D F ID+++G++KT LD E S++++A+D+G P ++S + V +KD NDN P D Y+ + E P G+ + + D D D
Sbjct: 1 MVEITVVDVNDNAPVFASDSYN---------VTILENITIPAVIATVKATDEDFGTNG---KVHYSMASS--SGIGGLTIDYSTGEVTLRERID----AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEEN-----VAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED-----FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDED 252 HSP 5 Score: 82.8037 bits (203), Expect = 1.419e-15 Identity = 121/490 (24.69%), Postives = 202/490 (41.22%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQF------NKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN--RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNV-KDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN--PLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
+ V+D ND P F+ Y + I E+ + ++ D+D G NGK+ + ASS+ + + V L+ ++D + + + + AKD QP SST + + V ++ND P ++ Q N I ++ R+Y D+D+ + I E F + + + IK+ DRET + + + D G L + + V++KDINDNAP F Y + E R ++I+T+ A D DE + + Y I ++ + I + G + ++ G + V +EISA D G + +VNV D ++ P + +S ++ E+ PIG V + D D N + + S + Q F ID SG I LDRE + + AS+ PL+ + +I V ++ D NDNSP
Sbjct: 4 ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSG---IGGLTIDYSTGEVTLR--ERIDAKN-SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVY---------------AIDEDSGPNGIIKYSMEGSEDFII----------DEDSGLIKTTKLLDRETTARYSLKVTARDM-GTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLK-----AVDNDEDQK--ITYRIEEADREVFSILDIG-DQGAILSVSGELKRQDHKVRVEISATDQG----GLQGRCVVNVFIDDVNSAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNAR--------------IVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLN----------TSTQIEVILD--DINDNSP 423
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 115.546 bits (288), Expect = 1.256e-25 Identity = 163/641 (25.43%), Postives = 262/641 (40.87%), Query Frame = 3
Query: 660 QIDREFIDRIEFTLIAVD-------GGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRK---TYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL-----ATDKDE--GENGTVEYYI-SNVVDDMKNYFSIDKNTGVVKTILGLDYE--KIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDY----GKDLFR------QFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDY-GMLCAMEKL--PPIGDYKTVIVAEDGDFNNSRK 2483
+ DRE ID T+ A D G P K K+ + + D ND P F + Y ++KESE G +++ ++ D D +N + + A + F + + +K LD+E ++Y L+A D G+ ++T V + + +VND+ P QF + ++YA I E V+ V TD D S S+ + L + V K T E+ +D D + +V + + N L ++V ++DINDN+P+F R +G ++ENR I+ D + A D D+ EN +EY I N + + ++ F ID+NTG + + LD E + IE+ A D GVP R + + V D NDN P + + Y + E PIG V + D D + D +FT Y V D++ S Q ++ PLDY +D F R E +V V ++D+ND++P + + +V+ P + I Y D D G+ ++ R+ +++ T D G L L I Y +I A D N R+
Sbjct: 1285 KFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGG----RIPFGVRTDSGTIFVK--EPLDFEASDQYHLVLIASD-GR--HNATTNVYIHIEDVNDNAP-----QFEQ---QKYATTVIEEDVDIPKVLFNVHATDADQDEKS-------SRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE-RLFGYIEENRE----PIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDAD-----------------------EEAKDNVFTYQLSEESDYFYVTTDKD-SKQSSVGVLRVK-QPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGR---------------YTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQ 1856 HSP 2 Score: 85.5001 bits (210), Expect = 2.268e-16 Identity = 169/710 (23.80%), Postives = 286/710 (40.28%), Query Frame = 3
Query: 177 DHIGRSGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLM------TEDFVDNKQPILIVK--HQI-DREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--SINFASSTNQDIQNT---FQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVK-VTDDDNQADSITCEIETS------QESFYLNALKTNAVLENRKTY---EIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV--NEIVTINKDPIL---ATDKD-EGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSS-------VKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
D GRS K + F + E T G V LR + + N + Q G CC++ + + I + D+N+N P FP+ Y +I + + + P VE+ + + + N D+ + L + FV ++Q ++ H + DRE R + T+ A D G P G + ++V+D ND PQF + YE + E G ++ + D D+ +N +I S+ ++ ++ QN F+L G + LI + +T K+ FN++A D G P S+A V + V + P KP I ++E + VI + V+ D++ + ++ S ES + K EN + I +D+++ ++ ++ + T+ +++ T V ++D+ND P F+ + G + E + N PI+ A D D +G V Y I + + +F ID+ TG + D EKI + + A D V + VK+ + + D NDN P + Y + E+E G V + D D N + L G G F + +SG I+ K LD E S Q +IAS+ R +V ++I D NDN+P
Sbjct: 786 DKNGRSTQKMNLFSIDEHT-------GLVKLRHGVSAADLAEAENPINLTVIVQD-DGSCCVY----PSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVK-------VEATD-DDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSG-EITLIKPIPMKT-QKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKP------GITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNK----FENGNEWVEVVIMEGLDYEQ----VNNYTLTLTATDMTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYH-------LIGAGGGRIP-----FGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG-------------RHNATTNVYIHIEDVNDNAP 1434 HSP 3 Score: 75.0998 bits (183), Expect = 2.879e-13 Identity = 98/414 (23.67%), Postives = 169/414 (40.82%), Query Frame = 3
Query: 729 RKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISI-----NFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINK----YSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTN----KLEVIIKDINDNAPVF-SSPRYYGIVKENRVNEIVTINKDP-----ILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVV--KTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDT 1904
R+ + +++ D ND P F++ +Y +++E +L + DKD+G+N +I+ NF+ ++N +I +LD + +N+ Y FN+ A+D G+P SS+A++ + N ND + VF P S+ A ++ E + ++ D D + + + + + +N + K S D ++ IV D +T+ L + I+D+N+N P F +Y I K + E T DP + ATD D NG + Y + + + F ID+ TGV+ + D E + + A D G + V V D NDN P+ + Y + E +GT V V D D
Sbjct: 622 RESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNGEISAKV---------------RLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDE--SAVFL----PTSQYTA--FVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAK---IME-GTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDA 1008 HSP 4 Score: 65.0846 bits (157), Expect = 3.518e-10 Identity = 117/498 (23.49%), Postives = 202/498 (40.56%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQID------REFIDRIEFTLIAVDGGKPPRKGKTKII-LKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKL---ISKLDY-ETINKYSFNLVAKDFGQ----PPRSST--ALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIY-INEGTTKDMVICLVKV--TDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEI--KSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYI-------SNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVP-VRSSSVKLIVNVKDTNDNQPEVDLS 1826
NDN PTF Y ++ E+ +N I A D D +N + + + +F N + K ++D R F+ R F + A D G+P + +I ++ + ND F SQ Y + E G ++ ++ D D +++ +F + Q S H +KL +S D E N + ++ +D G P ++ T A + + + +VN++ P P +Y+ I I EGT K +VKV TDDD+ A+ + +Y + A + +R+T + + FDRET+ V++ +D G L + V + DINDN+P F P Y V E V + + A D D N + Y + +D+ + +++ +G + I + + K + + A D G+P SS ++ +NV D P+ S
Sbjct: 636 NDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKD-------------TGDNSRITYSVDNHNFSINSNGEISAKVRLDADQLNERHFVYR--FNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQ--YTAFVAEDAQGGTPVIQIQARDAD---RDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEF-------PDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANG-----DIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATD-RGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSR---FEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFI-FNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTS 1096 HSP 5 Score: 63.5438 bits (153), Expect = 1.028e-9 Identity = 90/361 (24.93%), Postives = 154/361 (42.66%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDAD-DLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQP---ILIVKHQIDREFI-DRIEFTL-IAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQ--ADSITCEIETS-QESFYLNALKTNAVLENRKTYEIKSKIDFDRET----KTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDN 1475
NDN+P F + Y + E + I + + A+DAD + V +Y++ + ++ YF + T+ D+KQ +L VK +D E + R F L I V G+ + + + ++D ND P E +++E G + D+D+G+ + IN S D + F + Q L++ LD E I Y NL+ + + +V V++ +VND+ P +P + I+ + C ++ TD D T E+ S + S YLN + + I +FDRE K L + ++ +D G + + VII D+NDN
Sbjct: 1655 NDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESD----YFYVTTDK--DSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGR--HDAEAAVHVALVDRNDHAPHIHGAT-EHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQS----DPKRQFTIDQD---GTLRVAHTLDREDIAVY--NLIIEAYDNSNNIGRQMVAVYLQDVNDNGP--------EPYTVPRPCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQEFDREAPVPGKILE-IPLILADRAG---RRNEASVHVIIGDLNDN 1985 HSP 6 Score: 54.6842 bits (130), Expect = 4.245e-7 Identity = 99/409 (24.21%), Postives = 164/409 (40.10%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKP-NENFDVYFKLMTEDFVDNKQPILI--------VKHQIDREFIDRIEFTL--IAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--------SINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAP-VFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENG 1595
NDNSP FPE+ + I EN + P+ D V++ + + P EN ++ + ++ ++ + I +DRE EF + A D G P R+G + +KV D ND P F + YE ++E+ G ++ D D + S F +T++D + Q+ GV L++ LDYE + + + + A V V + + ND P+I ++ R + GT+ I TD D D+ I + + + L T DRE ++ + I D N + + + V ++D+NDN P ++ PR I +EN VN++ T I ATD+D E G
Sbjct: 1540 NDNSPIFPER-LFGYIEENRE-------PIHSDGVYF-MDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSK------QSSVGV-LRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPHI------HGATEHRVREDVPRGTS----IGRYTATDRD-AGDTARFRINRQSDPKRQFTIDQDGTLRVAHT--------LDREDIAVYNLIIEAYDNS--NNIGR-QMVAVYLQDVNDNGPEPYTVPRPC-IFRENTPVNQLGTCE---IRATDRDTAEFG 1906 HSP 7 Score: 52.373 bits (124), Expect = 2.433e-6 Identity = 124/517 (23.98%), Postives = 214/517 (41.39%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL----MTEDFVDNK--QPILIVKHQIDRE---FIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESE---MTGLELLHLRVEDKDSGNNGKISINFASSTNQDI--QNTFQLSQTLHGVALKLISKLDYETINKYSF--NLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQES--FYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHF-VSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIV----TINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPI---GTYVGKVNVTDKDT 1904
NDN+P F ++ Y ++E + +P F V + + ++ ++ + ++L E F K I +VK +DR+ + F + A+D G + + V D ND P F + ++ + E G+ + ++ D D +I + N+ I ++ F++ Q + + LD E ++ F + A D G P R A V + VT++ND+ P F++ K + E + D D +A + S+ES FY+ K ++ + +K +D++ T+ F + I SD + + V + D ND+A P +G E+RV E V +I + ATD+D G+ T + I N D K F+ID++ G ++ LD E I ++ I A D + V V ++D NDN PE EN P+ GT ++ TD+DT
Sbjct: 1430 NDNAPQFEQQKYATTVIEED-----VDIPKVL------FNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVK-ALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIF--AMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAP---FFE------KTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDK-DSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSD----GRHDAEAAVHVALVDRNDHA-----PHIHG-ATEHRVREDVPRGTSIGR--YTATDRDAGD--TARFRI-NRQSDPKRQFTIDQD-GTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQMVA--VYLQDVNDNGPEPYTVPRPCIFRENTPVNQLGTC--EIRATDRDT 1902 HSP 8 Score: 51.9878 bits (123), Expect = 3.055e-6 Identity = 117/513 (22.81%), Postives = 207/513 (40.35%), Query Frame = 3
Query: 750 ILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVED----KDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINK-YSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDR-ETKTLHFV---SIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF-SSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMK-NYFSIDKNTGVVKTILGLDYEKIKH----VSIEISAKDLG------VPVRSSSVKLIVNVKDTNDNQPEV-DLSFYS--FELYENEPIGTY------VGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTK--VVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
IL++L ++ PQF++ YE+ + E + ++ ++ + +D + G I+ + T +D F++ + + L + D + K + + A+ + R S + + + +VND+ P F +P+ R E + I V D D +S IT ++ S N EI +K+ D + HFV ++ D L + + + ++ ND + VF + +Y V E+ I I A D D E T + N K N FSID++TG+VK G+ + +++ + +D G +S L++ ++D N+N+PE D + YS ++ E GTY + KV TD D+ N + T + + F ID ++G + VV DRE + + A++ D F QF +V ++D NDNSP
Sbjct: 518 ILEIL-ADERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAR---EDNRESHVDLTIRIDDVNDNVPT-----FTRPLYTAQVR----EDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNG-------------EISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQ---IQARDADRDEV-TYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIME----GTYKTDPPTIVKVEATDDDSSANGDIVYSLYY---------TQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRG--DRPLIGFCQF--------SVEVVDINDNSP 977
BLAST of Protocadherin-1 vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 115.546 bits (288), Expect = 1.256e-25 Identity = 163/641 (25.43%), Postives = 262/641 (40.87%), Query Frame = 3
Query: 660 QIDREFIDRIEFTLIAVD-------GGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRK---TYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL-----ATDKDE--GENGTVEYYI-SNVVDDMKNYFSIDKNTGVVKTILGLDYE--KIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDY----GKDLFR------QFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDY-GMLCAMEKL--PPIGDYKTVIVAEDGDFNNSRK 2483
+ DRE ID T+ A D G P K K+ + + D ND P F + Y ++KESE G +++ ++ D D +N + + A + F + + +K LD+E ++Y L+A D G+ ++T V + + +VND+ P QF + ++YA I E V+ V TD D S S+ + L + V K T E+ +D D + +V + + N L ++V ++DINDN+P+F R +G ++ENR I+ D + A D D+ EN +EY I N + + ++ F ID+NTG + + LD E + IE+ A D GVP R + + V D NDN P + + Y + E PIG V + D D + D +FT Y V D++ S Q ++ PLDY +D F R E +V V ++D+ND++P + + +V+ P + I Y D D G+ ++ R+ +++ T D G L L I Y +I A D N R+
Sbjct: 1285 KFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGG----RIPFGVRTDSGTIFVK--EPLDFEASDQYHLVLIASD-GR--HNATTNVYIHIEDVNDNAP-----QFEQ---QKYATTVIEEDVDIPKVLFNVHATDADQDEKS-------SRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE-RLFGYIEENRE----PIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDAD-----------------------EEAKDNVFTYQLSEESDYFYVTTDKD-SKQSSVGVLRVK-QPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGR---------------YTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQ 1856 HSP 2 Score: 85.5001 bits (210), Expect = 2.268e-16 Identity = 169/710 (23.80%), Postives = 286/710 (40.28%), Query Frame = 3
Query: 177 DHIGRSGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLM------TEDFVDNKQPILIVK--HQI-DREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--SINFASSTNQDIQNT---FQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVK-VTDDDNQADSITCEIETS------QESFYLNALKTNAVLENRKTY---EIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV--NEIVTINKDPIL---ATDKD-EGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSS-------VKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
D GRS K + F + E T G V LR + + N + Q G CC++ + + I + D+N+N P FP+ Y +I + + + P VE+ + + + N D+ + L + FV ++Q ++ H + DRE R + T+ A D G P G + ++V+D ND PQF + YE + E G ++ + D D+ +N +I S+ ++ ++ QN F+L G + LI + +T K+ FN++A D G P S+A V + V + P KP I ++E + VI + V+ D++ + ++ S ES + K EN + I +D+++ ++ ++ + T+ +++ T V ++D+ND P F+ + G + E + N PI+ A D D +G V Y I + + +F ID+ TG + D EKI + + A D V + VK+ + + D NDN P + Y + E+E G V + D D N + L G G F + +SG I+ K LD E S Q +IAS+ R +V ++I D NDN+P
Sbjct: 786 DKNGRSTQKMNLFSIDEHT-------GLVKLRHGVSAADLAEAENPINLTVIVQD-DGSCCVY----PSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVK-------VEATD-DDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSG-EITLIKPIPMKT-QKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKP------GITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNK----FENGNEWVEVVIMEGLDYEQ----VNNYTLTLTATDMTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYH-------LIGAGGGRIP-----FGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG-------------RHNATTNVYIHIEDVNDNAP 1434 HSP 3 Score: 75.0998 bits (183), Expect = 2.879e-13 Identity = 98/414 (23.67%), Postives = 169/414 (40.82%), Query Frame = 3
Query: 729 RKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISI-----NFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINK----YSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTN----KLEVIIKDINDNAPVF-SSPRYYGIVKENRVNEIVTINKDP-----ILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVV--KTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDT 1904
R+ + +++ D ND P F++ +Y +++E +L + DKD+G+N +I+ NF+ ++N +I +LD + +N+ Y FN+ A+D G+P SS+A++ + N ND + VF P S+ A ++ E + ++ D D + + + + + +N + K S D ++ IV D +T+ L + I+D+N+N P F +Y I K + E T DP + ATD D NG + Y + + + F ID+ TGV+ + D E + + A D G + V V D NDN P+ + Y + E +GT V V D D
Sbjct: 622 RESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNGEISAKV---------------RLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDE--SAVFL----PTSQYTA--FVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAK---IME-GTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDA 1008 HSP 4 Score: 65.0846 bits (157), Expect = 3.518e-10 Identity = 117/498 (23.49%), Postives = 202/498 (40.56%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQID------REFIDRIEFTLIAVDGGKPPRKGKTKII-LKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKL---ISKLDY-ETINKYSFNLVAKDFGQ----PPRSST--ALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIY-INEGTTKDMVICLVKV--TDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEI--KSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYI-------SNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVP-VRSSSVKLIVNVKDTNDNQPEVDLS 1826
NDN PTF Y ++ E+ +N I A D D +N + + + +F N + K ++D R F+ R F + A D G+P + +I ++ + ND F SQ Y + E G ++ ++ D D +++ +F + Q S H +KL +S D E N + ++ +D G P ++ T A + + + +VN++ P P +Y+ I I EGT K +VKV TDDD+ A+ + +Y + A + +R+T + + FDRET+ V++ +D G L + V + DINDN+P F P Y V E V + + A D D N + Y + +D+ + +++ +G + I + + K + + A D G+P SS ++ +NV D P+ S
Sbjct: 636 NDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKD-------------TGDNSRITYSVDNHNFSINSNGEISAKVRLDADQLNERHFVYR--FNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQ--YTAFVAEDAQGGTPVIQIQARDAD---RDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEF-------PDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANG-----DIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATD-RGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSR---FEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFI-FNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTS 1096 HSP 5 Score: 63.5438 bits (153), Expect = 1.028e-9 Identity = 90/361 (24.93%), Postives = 154/361 (42.66%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDAD-DLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQP---ILIVKHQIDREFI-DRIEFTL-IAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQ--ADSITCEIETS-QESFYLNALKTNAVLENRKTYEIKSKIDFDRET----KTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDN 1475
NDN+P F + Y + E + I + + A+DAD + V +Y++ + ++ YF + T+ D+KQ +L VK +D E + R F L I V G+ + + + ++D ND P E +++E G + D+D+G+ + IN S D + F + Q L++ LD E I Y NL+ + + +V V++ +VND+ P +P + I+ + C ++ TD D T E+ S + S YLN + + I +FDRE K L + ++ +D G + + VII D+NDN
Sbjct: 1655 NDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESD----YFYVTTDK--DSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGR--HDAEAAVHVALVDRNDHAPHIHGAT-EHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQS----DPKRQFTIDQD---GTLRVAHTLDREDIAVY--NLIIEAYDNSNNIGRQMVAVYLQDVNDNGP--------EPYTVPRPCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQEFDREAPVPGKILE-IPLILADRAG---RRNEASVHVIIGDLNDN 1985 HSP 6 Score: 54.6842 bits (130), Expect = 4.245e-7 Identity = 99/409 (24.21%), Postives = 164/409 (40.10%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKP-NENFDVYFKLMTEDFVDNKQPILI--------VKHQIDREFIDRIEFTL--IAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--------SINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAP-VFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENG 1595
NDNSP FPE+ + I EN + P+ D V++ + + P EN ++ + ++ ++ + I +DRE EF + A D G P R+G + +KV D ND P F + YE ++E+ G ++ D D + S F +T++D + Q+ GV L++ LDYE + + + + A V V + + ND P+I ++ R + GT+ I TD D D+ I + + + L T DRE ++ + I D N + + + V ++D+NDN P ++ PR I +EN VN++ T I ATD+D E G
Sbjct: 1540 NDNSPIFPER-LFGYIEENRE-------PIHSDGVYF-MDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSK------QSSVGV-LRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPHI------HGATEHRVREDVPRGTS----IGRYTATDRD-AGDTARFRINRQSDPKRQFTIDQDGTLRVAHT--------LDREDIAVYNLIIEAYDNS--NNIGR-QMVAVYLQDVNDNGPEPYTVPRPC-IFRENTPVNQLGTCE---IRATDRDTAEFG 1906 HSP 7 Score: 52.373 bits (124), Expect = 2.433e-6 Identity = 124/517 (23.98%), Postives = 214/517 (41.39%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL----MTEDFVDNK--QPILIVKHQIDRE---FIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESE---MTGLELLHLRVEDKDSGNNGKISINFASSTNQDI--QNTFQLSQTLHGVALKLISKLDYETINKYSF--NLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQES--FYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHF-VSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIV----TINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPI---GTYVGKVNVTDKDT 1904
NDN+P F ++ Y ++E + +P F V + + ++ ++ + ++L E F K I +VK +DR+ + F + A+D G + + V D ND P F + ++ + E G+ + ++ D D +I + N+ I ++ F++ Q + + LD E ++ F + A D G P R A V + VT++ND+ P F++ K + E + D D +A + S+ES FY+ K ++ + +K +D++ T+ F + I SD + + V + D ND+A P +G E+RV E V +I + ATD+D G+ T + I N D K F+ID++ G ++ LD E I ++ I A D + V V ++D NDN PE EN P+ GT ++ TD+DT
Sbjct: 1430 NDNAPQFEQQKYATTVIEED-----VDIPKVL------FNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVK-ALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIF--AMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAP---FFE------KTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDK-DSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSD----GRHDAEAAVHVALVDRNDHA-----PHIHG-ATEHRVREDVPRGTSIGR--YTATDRDAGD--TARFRI-NRQSDPKRQFTIDQD-GTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQMVA--VYLQDVNDNGPEPYTVPRPCIFRENTPVNQLGTC--EIRATDRDT 1902 HSP 8 Score: 51.9878 bits (123), Expect = 3.055e-6 Identity = 117/513 (22.81%), Postives = 207/513 (40.35%), Query Frame = 3
Query: 750 ILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVED----KDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINK-YSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDR-ETKTLHFV---SIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF-SSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMK-NYFSIDKNTGVVKTILGLDYEKIKH----VSIEISAKDLG------VPVRSSSVKLIVNVKDTNDNQPEV-DLSFYS--FELYENEPIGTY------VGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTK--VVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
IL++L ++ PQF++ YE+ + E + ++ ++ + +D + G I+ + T +D F++ + + L + D + K + + A+ + R S + + + +VND+ P F +P+ R E + I V D D +S IT ++ S N EI +K+ D + HFV ++ D L + + + ++ ND + VF + +Y V E+ I I A D D E T + N K N FSID++TG+VK G+ + +++ + +D G +S L++ ++D N+N+PE D + YS ++ E GTY + KV TD D+ N + T + + F ID ++G + VV DRE + + A++ D F QF +V ++D NDNSP
Sbjct: 518 ILEIL-ADERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAR---EDNRESHVDLTIRIDDVNDNVPT-----FTRPLYTAQVR----EDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNG-------------EISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQ---IQARDADRDEV-TYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIME----GTYKTDPPTIVKVEATDDDSSANGDIVYSLYY---------TQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRG--DRPLIGFCQF--------SVEVVDINDNSP 977
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 186.808 bits (473), Expect = 2.272e-47 Identity = 172/626 (27.48%), Postives = 280/626 (44.73%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQI----DREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--SINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPP--NIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENR--KTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDP------ILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTST 2261
NDN+PTFP+ + + E EN+ + +L A D D P+ + Y I N N F+L + D +L + QI DRE + A+DGG PP +G + + + D ND +P F+Q Y + E+ G +L + D D+ NG + +IN S D + F++ A+ + LD+ET + +VAKD G+ P +TA V + VT+VND+ P N++F + A I+E + + V D D++ + + LN + L R Y + + DRE + + +S+V +D +G L + + + I D+NDN P F Y+ V E DP +LA D+DEG N + Y ++ + +F ID TG++ T +D E + + A+D GVP SS+ ++V + D NDN+P D SFY+ + ENEP+G + KV+ +D D +N T+G F + + SG+I LD E S F ++A++ L + + + + D NDN P+ ++ +P+ S +ST
Sbjct: 168 NDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVND--AFRLSSHRERDG---VLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQS---DKEQMFRIDPRTG--AIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDD-------ASPKISESAQPGEFVARISVHDPDSKTEYANVNVT-------LNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATD-KGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEV---------ADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNY----------TIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGL------------STTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASST 737 HSP 2 Score: 152.14 bits (383), Expect = 1.214e-36 Identity = 182/723 (25.17%), Postives = 317/723 (43.85%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDN-----KQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISK--LDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNK-LEVIIKDINDNAPVFSSPRYYGIVKENR-----VNEIVTINK--DPILATDKDEGENGTVEYYISNVVDDM-KNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVP--VRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQ-PADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKV--RVTMKNND-YFSLTPDYGMLCAMEKLPPI-------GDYKTVIVAEDGDFNNSRKQEFLINIHI 2510
NDN P F + Y + E+ IN++I A D D +Y I + +V + + D + + ++ +DRE DR + T++A D G P KT++I++VLD ND +P+F + YE +I+E+ G + + D D G N I + I ++FQ +H V ++ ++ LD E Y + A+D G P RS+ V + V++VND+ P I Q + + E + V+ D D Q SIT I ++S + + I++++ D E ++++ + + SD G N ++T + L V + D+NDN P F+S V+E+ V I I + D + + ++ E+ V Y ++ + D+ + F ID+++G + LD E +EI A D +SS++ + + V D NDN PE ++ E P+GT + TD DT N I+ P L SQ A +F +D+ +G + + LD E + + A LD ++ + + + ++V + ILD ND++P + P FI +T V + VD D G+N ++ +T N + F + G++ ++ LPP G + +I A+D +K +N+H+
Sbjct: 1030 NDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVD-NVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLP-----INSSFQ----VHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIA--------DPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPT-----SGVIRTRVVLDHEERSIYRLGVAASD--GGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYF---PQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQA-----LDQSSNVTERLQTS--VTVRLRILDANDHAPHFV---SPNSSGGKTASLFISDATR-----IGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSS--LNLHL 1707 HSP 3 Score: 137.502 bits (345), Expect = 3.467e-32 Identity = 187/786 (23.79%), Postives = 320/786 (40.71%), Query Frame = 3
Query: 273 RPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGK-PPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNI--------VFYQFNKPISKQYARIYI--NEGTTKDMVICLVKVTDDDNQA-DSITCEIETSQESFY---------LNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVS----------------IVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKE--NRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKN-TGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPT--LGTSQPAD----QIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLD-EGENSKV-RVTMKNNDYFSLTPDYGMLCA-MEKLPPI----GDYKTVIVAEDG 2462
RP+DRE++ + + Q Q Q I I D NDN+P F Y + E++ + + + A DAD GV + + + + + + +D + ++ ++DRE F ++A DGG+ R + + VLD ND P F + Y ++ G LL ++ D D G N +I + ++ N + F+++ + AL L E+ +VA+D G PP+SS L+E+ + P + V + N P + ++ ++G + + +D + DS++ EI ++ ++AL L + + S+ D + T++ ++ ++ + T L +L + ++D NDN+P FS ++ V E N+ + ++ A D D G N + Y+I V + N F I+ +G+V+T + LD E ++I A D GVP + + + V + D NDNQP + + E +G + ++ D DT P T LG D IF +D SGK+ K LD E+ + +IAS D + R + TV + D+NDN+P+ + + P A+ P +S I S V F + V D D EG NSKV + + FS+ P G++ M +L P GDY I+A+D
Sbjct: 1907 RPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQ--------------NDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDAD---LGVNARLV------YSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSL-NAENSAVSAKFRINPSTG--ALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVH-----AFDSDAGSNARLRYHI--VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDT--------------YPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIAS---------DAAHEARTVL----TVRVNDENDNAPVFLAQQPPAYFAILPAISEISESL--------SVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDA 2623 HSP 4 Score: 124.79 bits (312), Expect = 2.571e-28 Identity = 167/673 (24.81%), Postives = 280/673 (41.60%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKES-----EMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT---DKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLG-TSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIAS-NPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN-NDYFSLTPDYGMLCAMEKL 2417
NDN P F + Y + EN + I + A D GV + N FK +TE V + + + ++D E EF ++A D G K +++ D ND P F Y++ ++ES + + ++ + D D GN G++S + I F++ ++ + + L T + N+ A D G ++ A+V + + + PP F K Y + I GT +V ++ + D + I + Y +++TN + I+ D E K+ ++I T G + ++ + ++D+NDNAP F + V E+ E+ P+ A DKD G +G V Y + V + K F+ID +G + LDYE + ++ ++A D GVP S+++ ++V+V+D NDN P + YS + E+ I + +VN +D DT N + + + T +S Q F I SG IY + LDRE + ++A+ N P + K V V +LD NDN P K K + + EN+ + V DLD GEN+ +R ++ N F + P G + E L
Sbjct: 605 NDNEPIFDQSFYNVSVAENEPVGRCI---LKVSASDPDCGVNAMV----NYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIK--MQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGI---FRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPP-----IFEKARYNYYVKEDIPRGT---VVGSVIAASGDVAHRSPVRYSIYSGDPDGYF-SIETN-------SGNIRIAKPLDHEAKSQVLLNIQA--TLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESA--EL----GAPLYAAHAHDKDSGSSGQVTYSL--VKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAK-----------TRVIVRVLDANDNDPKFQ-KSKYEFR------------IEENLRRGSVVGV-VTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPL 1214 HSP 5 Score: 122.479 bits (306), Expect = 1.320e-27 Identity = 170/710 (23.94%), Postives = 304/710 (42.82%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDAD-----DLPFGVESY--EIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVD-GGKPPRKGKTKII--LKVLDENDCEPQF------SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQL-SQTLHGVALKLISKL-----DYETINKYSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQY-ARIYINEGTTKDMVIC---------LVKVTDD----DNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI-VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVP-VRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKP---QVKA-VNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDY-----FSLTPDYGMLCAMEKL 2417
NDN+P +P+ ++ E + + + I A DAD DL + + Y ++ + E F++ D+ L ++ +D E + + A+D + +T + L++LD ND P F + I ++ G + H+ D+DSG+NG+++ T + + F++ SQT G+ ++L+ L D E +++ + AKD GQP P+ S+ + + V +++PP + + I + + ++ + T K + V +D D Q IT + +ES L NR++ S + R + ++ DT Q + + + D+NDN+P F YG+ V EN ++ ++A+D DEG N + Y I+ ++ N FSID ++G + + LD E+ +++I A D G P R + + V+D NDN P LS Y+ + E+ P+GT V +++ D D +N + + F ID +SG I T LDRE+ + F ++A+ D G+ R + + V +N+LD NDN P + + P QV A + P + +K +D D G N+++ ++ + F + P G L A + L
Sbjct: 1479 NDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRM------DSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEI---TGGNGEGRFRINSQT--GI-IELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSI-------GDTSN-GQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHT----VVASDLDEGPNADLIYSITG--GNLGNKFSIDSSSGEL-SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARL------------VYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLAT-----DGGRYEVR----SATVPVQINVLDINDNRP--IFERYPYIGQVPALIQPGQTLLKVQA----------------LDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSL 2122 HSP 6 Score: 101.293 bits (251), Expect = 3.745e-21 Identity = 129/520 (24.81%), Postives = 215/520 (41.35%), Query Frame = 3
Query: 687 IEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDN--------QADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSS---PRYYGIVKE-NRVNEIVTINKDPIL--ATDKD-EGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVS---IEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPM 2192
I L+A P ++++++ DEND P+FSQ + + E G + + D D+G+N ++ + N D N F + G+ I LD E + Y ++A D G P + TA + V + +VND N+P + ++E T VI + D D A+S T +IE + F L+ VL+ R YE++ + + D ++ SD + L V + D NDNAPVF + P Y+ I+ + ++E ++++ D + ATD D EG N V Y +++ + FS+ + GVV + + + I AKD G P SS L V D + + + Y ++ E P+G+ V ++ D + G + A ++ +S I LDRE + ++ S+P +G L + ISV + ILD NDN P+
Sbjct: 2288 IRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDG-NHD--NAFVIEPAFSGIVRTNI-VLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVND----------NQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAES-TVDIE-NMSIFALDRYSGKLVLKRRLDYELQQEYELD----------VIASDAAH----EARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY----IIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIA--------------GNEESAFELL----QSKAIVLVKPLDRERNDLYKLRLVLSHP----HGPPLISSLNSSSGISVIITILDANDNFPI 2751 HSP 7 Score: 94.3597 bits (233), Expect = 4.921e-19 Identity = 188/828 (22.71%), Postives = 321/828 (38.77%), Query Frame = 3
Query: 126 VEITETTVSLFELADVSDHIGRSGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREE--------YCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTF-PEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKP-PRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQ-PPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFY-LNALKTNAVLE---NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPV--FSSPRYYGIVKEN-----RVNEIVTI----------------NKDPILATDKDEGE-----------------------NGTVEYYISNVVDDMKNY--FSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNE-SGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKL 2417
+++T ++ E A++S I +G+ +D F++ +Q G +T R DRE Y +N+ T +S + IG SN I I V D+NDNSP F P Y + ENS+ I +A D D+ P Y I N + F + + +DRE R + A D G+P R+G I + V D+ND P+F Y ++E G ++ + D D G N ++ + A+ T +Q + + + KLD E Y+F ++A D G+ RS+T V++ V ++ND N+PI ++Y YI + V L++ + ++ ++ + E Y LNA + + N T + + E+ L + +V D +G +E++I + PV F + Y ++KEN R+ ++V + N+D IL+ D GE G +Y + + + S + + L + + + + A+ P +S +L++ ++D NDN P+ + + E GT+V +V+ D D N + D F I+ SG + T +VLDRE+ IIA+ D G T ++ V I+D NDN P + V E+ + TS + N + T+P + L ++ V ++N F+L G L +L
Sbjct: 1739 LQVTAKSLHGAENANLSYEI-PAGVANDLFHVD-----WQ--RGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDEGPNADLIYSITGGN---------LGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQ------WQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDIND----------NRPIFERYP--YIGQ------VPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARD-KGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHI-----------VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIAT-----DEGVPQM-----TGTATIRVQIVDVNDNQPTFPPNNLVTVSEAT-ELGAVITSISAN----DVDTYPALTYRL----GAESTVDIENMSIFALDRYSGKLVLKRRL 2493 HSP 8 Score: 89.7373 bits (221), Expect = 1.263e-17 Identity = 156/630 (24.76%), Postives = 259/630 (41.11%), Query Frame = 3
Query: 612 TEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKT-KIILKVLDENDCEPQFSQLIYEIKIKESEMTGLE--LLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS--QTLHGVA---LKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE--GTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF--------SSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNV-VDDMKNYFSI---DKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN--PLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM----KNNDYFSLTPDYGMLCAMEKL 2417
T+ +D + K ++DRE R ++L+A+ P G+ ++++ V DEND P F Q I+ E+ ++ LL R D + N + +I + ++ + F+LS + GV L++ LD ET YS + A D G PP V + + +VND+ P +F Q S+ +A + N GT+ V D++ + ++ +E + +T A+ N+ +DF ETK LH + +V D G L+ T + + + D+NDN P +SP+ I + + E V I D D EY NV ++ +F++ D + +V L LD E + + ++ + A D G P +S + + + D NDN PE + Y + E GT V +V D+D +N+ + T + Q F ID ++G I T+ +D E ++A + PL + +V V I D NDN P+ + SF S EN C+ D D G N+ V T+ K+ F + G +C +L
Sbjct: 121 TDLAIDRATGEIRTKVKLDRE--TRASYSLVAI-----PLSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNI-----VSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQ-----SRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINK-------ALDF--ETKELHELVVVAKD-HGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPK---ISESAQPGEFVA----RISVHDPDS----KTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAE---------TPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPL------------SSTATVLVTIHDVNDNEPIF-------------DQSFYNVSVAENEPVGRCI-LKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGEL 675 HSP 9 Score: 89.7373 bits (221), Expect = 1.386e-17 Identity = 164/742 (22.10%), Postives = 296/742 (39.89%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL--MTEDFV------DNKQPILIVKHQIDREFID--RIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKIS---INFASSTNQDIQNTFQLSQ--TLHGVALKLISKLDYETINKYSFNLVAKDFGQ--PPRSSTAL-VEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGT-TKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTN-KLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYI-SNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLG--VPVRSSSVK---------------------LIVNVKDTNDNQPEVD-LSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND--YFSLTPDYGMLCAMEKLPP--IGDYKTVIVAEDGDFNNSRKQEFLINIHI 2510
NDN PTF + + E++ + + + + P V +E+ E+ V + L +T+D + D L+V +DRE R+E + P+ + ++V D ND P++ Q ++++ E+ G + + D D+G NG + I + N+ + L + +L G AL L + LD+E + +Y + A D R T++ V + + + ND P+ F N K A ++I++ T ++V +V V +D +T EI ++E K+ ++ D ++ + F I+ + G + K+++ L +I++ ++N P F Y + EN + + + A EN + Y I + V +D+ F +D G++ T D E + + +D + SS+V+ + + V D NDN PE S Y + EN G + V +D D N I + G LG F+ID+ SG++ + LDRE S+ I AS D G+ RQ ++T+ + D+NDN+P L T + + P VD D G N+++ ++ N F++ G++ + KL Y +++A DG R + I++
Sbjct: 1359 NDNRPTFTSSSLVFRVREDAALGHVVG---SISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTG-ALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPH--FVSPNSSGGKT-ASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATE-DVEKGGR---FNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQ---VTAKSLHGAENANLSYEIPAGVANDL---FHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDEGPNADLIYS-----ITGGNLGNK------FSIDSSSGELSARP-LDREQHSRYTLQIQAS-----DRGQPKSRQ----GHCNITIFVEDQNDNAPRFKLSK--------------YTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINV 2047 HSP 10 Score: 87.4261 bits (215), Expect = 6.182e-17 Identity = 147/581 (25.30%), Postives = 246/581 (42.34%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLP-----FGVES-YEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEP---------QFSQLIYEIKIKESEMTGLELLHLRVEDKDS-GNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLD--YETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEG-----INQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIV----TINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEK-IKHVSIEISAKDLGVPVRSSSVK-LIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN 2087
NDN PTFP + E +++ + I+ A D D P G ES +IE N ++ +D L++K ++D E E +IA D + +T + ++V DEND P F+ L +I ES +LL + D DS GNN K+ + Q F + + +GV +S+L + Y ++AKD G+P S+ L+ V ND+ QF + QY R I+E V+ + + D I ++ES + +L+++ +K DRE L+ + +V S G + + I D NDN P+F Y E ++E+ +I + + D++ N V Y I++ D+ + F+ID TGV+ LDY+ K + I A D S++ + + D NDN+P+ L+ Y L ENEP+G+ V + + +D D ++ P P+ +S ++F +D+ESG + + V D E + ++AS+
Sbjct: 2422 NDNQPTFPPNNLVT-VSEATELGAVITSISANDVDTYPALTYRLGAESTVDIE----NMSIFA-------LDRYSGKLVLKRRLDYELQQEYELDVIASDAA---HEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYII-----EPAQEGFSVHPS-NGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRV---QANDNGSG--RSQF---LQNQY-RAQISEAAPLGSVVLQLG----QDALDQSLAIIAGNEESAF-------ELLQSKAIVLVKP---LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKY----EAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDE--HMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLD----KGPFGQLNYSIGPAPSDESSW---KMFRVDSESGLVTSAFVFDYEQRQRYDMELLASD 2945 HSP 11 Score: 75.8702 bits (185), Expect = 2.531e-13 Identity = 107/394 (27.16%), Postives = 163/394 (41.37%), Query Frame = 3
Query: 1320 NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEY-YISNVVDDMKNYFSIDKNTGVVKTILG----LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP---MMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND-YFSLTP-DYGMLCAMEKLPP----IGDYKTVIVAED 2459
+R T EI++K+ DRET+ + S+V G N ++ V +KD NDNAP F + EN E + + + A D D T Y +S V+D S + GV+ L LD E S+ I A D G P + + + ++D NDNQP + S Y + EN +GT V +V +D D D N + +Q+F ID +G IY LD E ++A KD Q +T V++ + D NDN P ++ L D +P++S E+ P V + + E + V VT+ D +F+LT D + + LP + +Y +VA D
Sbjct: 126 DRATGEIRTKVKLDRETRASY--SLVAIPLSGRNI-----RVLVTVKDENDNAPTFPQTSMHIEFPENTPRE---VKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRR---------QSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVA---------KDHGEQPLETTAF-VSIRVTDVNDNQPTINVIFLSDD-----ASPKIS-------ESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATD 478 HSP 12 Score: 73.559 bits (179), Expect = 1.280e-12 Identity = 103/419 (24.58%), Postives = 169/419 (40.33%), Query Frame = 3
Query: 699 LIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTAL------VEVFVTNVNDSPPNIVFYQFNKPISKQYAR--IYINEGTTKDMVICLVKVTDDDNQADSITCEI-----ETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNY--FSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENE--PIGTYVGKVNVTDKDT 1904
+IA D GKP K T + ++ D QF Q Y +I E+ G +L L + D S+ + + + F+L L A+ L+ LD E + Y LV PP S+ V + + + ND N PI + A+ I+E I ++ D D Q ++ E+ + E + L T + N +++D+D K+ + C D+ L + + D NDN P F Y + EN E V + A+D D+G G + Y I D ++ F +D +G+V + DYE+ + +E+ A D+G + +SV + V ++ ++ P+ Y F L P G VG+V TD D+
Sbjct: 2618 IIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQ------SLAIIAGNEE---SAFEL---LQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDAND----------NFPIFDRSAKYEAEISELAPLRYSIAQLQAIDAD-QENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVN-------NRLDYDSGAKSYELIIRAC-DSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAEN---EPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG--GKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDS 3000 HSP 13 Score: 69.707 bits (169), Expect = 1.623e-11 Identity = 115/504 (22.82%), Postives = 205/504 (40.67%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQI--DREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS--ITCEIETSQESFYLNALKTNAVLE---NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIE-ISAKDLGVP-----VRSSSVKLIVNVKDTNDNQPEVDLSF-YSFELYENEPIGTYVGKVNVTDKD 1901
NDNSP F +K + + E + + ++ A+D+D Y I N + FV IV+ I DRE D + +IA D G P G I ++++D ND +P F + SE T L + + D ++ + + DI+N + + L L +LDYE +Y +++A D R+ ++ V V + ND+ P + Q + A I+E + D + V TD D++ ++ + IE +QE F ++ +N V+ +R + S D+ FV I+ D G LK + L V D F +Y + E P+ + G++ ++ ++ + + ++ F + ++ +V + LD E+ + + + G P SS + +I+ + D NDN P D S Y E+ E P+ + ++ D D
Sbjct: 2316 NDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHD---------NAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPP---NNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEART---VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVH--PSNGVVSVNMSRLQPAVSSSGDY--------FVRIIAKDA-GKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISE----------AAPLGSVVLQLGQDA-LDQSLAIIAGNEESAFELLQSKAIV-LVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDAD 2781
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 186.808 bits (473), Expect = 2.272e-47 Identity = 172/626 (27.48%), Postives = 280/626 (44.73%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQI----DREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--SINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPP--NIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENR--KTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDP------ILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTST 2261
NDN+PTFP+ + + E EN+ + +L A D D P+ + Y I N N F+L + D +L + QI DRE + A+DGG PP +G + + + D ND +P F+Q Y + E+ G +L + D D+ NG + +IN S D + F++ A+ + LD+ET + +VAKD G+ P +TA V + VT+VND+ P N++F + A I+E + + V D D++ + + LN + L R Y + + DRE + + +S+V +D +G L + + + I D+NDN P F Y+ V E DP +LA D+DEG N + Y ++ + +F ID TG++ T +D E + + A+D GVP SS+ ++V + D NDN+P D SFY+ + ENEP+G + KV+ +D D +N T+G F + + SG+I LD E S F ++A++ L + + + + D NDN P+ ++ +P+ S +ST
Sbjct: 168 NDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVND--AFRLSSHRERDG---VLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQS---DKEQMFRIDPRTG--AIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDD-------ASPKISESAQPGEFVARISVHDPDSKTEYANVNVT-------LNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATD-KGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEV---------ADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNY----------TIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGL------------STTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASST 737 HSP 2 Score: 152.14 bits (383), Expect = 1.214e-36 Identity = 182/723 (25.17%), Postives = 317/723 (43.85%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDN-----KQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISK--LDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNK-LEVIIKDINDNAPVFSSPRYYGIVKENR-----VNEIVTINK--DPILATDKDEGENGTVEYYISNVVDDM-KNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVP--VRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQ-PADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKV--RVTMKNND-YFSLTPDYGMLCAMEKLPPI-------GDYKTVIVAEDGDFNNSRKQEFLINIHI 2510
NDN P F + Y + E+ IN++I A D D +Y I + +V + + D + + ++ +DRE DR + T++A D G P KT++I++VLD ND +P+F + YE +I+E+ G + + D D G N I + I ++FQ +H V ++ ++ LD E Y + A+D G P RS+ V + V++VND+ P I Q + + E + V+ D D Q SIT I ++S + + I++++ D E ++++ + + SD G N ++T + L V + D+NDN P F+S V+E+ V I I + D + + ++ E+ V Y ++ + D+ + F ID+++G + LD E +EI A D +SS++ + + V D NDN PE ++ E P+GT + TD DT N I+ P L SQ A +F +D+ +G + + LD E + + A LD ++ + + + ++V + ILD ND++P + P FI +T V + VD D G+N ++ +T N + F + G++ ++ LPP G + +I A+D +K +N+H+
Sbjct: 1030 NDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVD-NVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLP-----INSSFQ----VHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIA--------DPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPT-----SGVIRTRVVLDHEERSIYRLGVAASD--GGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYF---PQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQA-----LDQSSNVTERLQTS--VTVRLRILDANDHAPHFV---SPNSSGGKTASLFISDATR-----IGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSS--LNLHL 1707 HSP 3 Score: 137.502 bits (345), Expect = 3.467e-32 Identity = 187/786 (23.79%), Postives = 320/786 (40.71%), Query Frame = 3
Query: 273 RPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGK-PPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNI--------VFYQFNKPISKQYARIYI--NEGTTKDMVICLVKVTDDDNQA-DSITCEIETSQESFY---------LNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVS----------------IVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKE--NRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKN-TGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPT--LGTSQPAD----QIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLD-EGENSKV-RVTMKNNDYFSLTPDYGMLCA-MEKLPPI----GDYKTVIVAEDG 2462
RP+DRE++ + + Q Q Q I I D NDN+P F Y + E++ + + + A DAD GV + + + + + + +D + ++ ++DRE F ++A DGG+ R + + VLD ND P F + Y ++ G LL ++ D D G N +I + ++ N + F+++ + AL L E+ +VA+D G PP+SS L+E+ + P + V + N P + ++ ++G + + +D + DS++ EI ++ ++AL L + + S+ D + T++ ++ ++ + T L +L + ++D NDN+P FS ++ V E N+ + ++ A D D G N + Y+I V + N F I+ +G+V+T + LD E ++I A D GVP + + + V + D NDNQP + + E +G + ++ D DT P T LG D IF +D SGK+ K LD E+ + +IAS D + R + TV + D+NDN+P+ + + P A+ P +S I S V F + V D D EG NSKV + + FS+ P G++ M +L P GDY I+A+D
Sbjct: 1907 RPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQ--------------NDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDAD---LGVNARLV------YSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSL-NAENSAVSAKFRINPSTG--ALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVH-----AFDSDAGSNARLRYHI--VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDT--------------YPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIAS---------DAAHEARTVL----TVRVNDENDNAPVFLAQQPPAYFAILPAISEISESL--------SVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDA 2623 HSP 4 Score: 124.79 bits (312), Expect = 2.571e-28 Identity = 167/673 (24.81%), Postives = 280/673 (41.60%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKES-----EMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT---DKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLG-TSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIAS-NPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN-NDYFSLTPDYGMLCAMEKL 2417
NDN P F + Y + EN + I + A D GV + N FK +TE V + + + ++D E EF ++A D G K +++ D ND P F Y++ ++ES + + ++ + D D GN G++S + I F++ ++ + + L T + N+ A D G ++ A+V + + + PP F K Y + I GT +V ++ + D + I + Y +++TN + I+ D E K+ ++I T G + ++ + ++D+NDNAP F + V E+ E+ P+ A DKD G +G V Y + V + K F+ID +G + LDYE + ++ ++A D GVP S+++ ++V+V+D NDN P + YS + E+ I + +VN +D DT N + + + T +S Q F I SG IY + LDRE + ++A+ N P + K V V +LD NDN P K K + + EN+ + V DLD GEN+ +R ++ N F + P G + E L
Sbjct: 605 NDNEPIFDQSFYNVSVAENEPVGRCI---LKVSASDPDCGVNAMV----NYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIK--MQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGI---FRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPP-----IFEKARYNYYVKEDIPRGT---VVGSVIAASGDVAHRSPVRYSIYSGDPDGYF-SIETN-------SGNIRIAKPLDHEAKSQVLLNIQA--TLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESA--EL----GAPLYAAHAHDKDSGSSGQVTYSL--VKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAK-----------TRVIVRVLDANDNDPKFQ-KSKYEFR------------IEENLRRGSVVGV-VTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPL 1214 HSP 5 Score: 122.479 bits (306), Expect = 1.320e-27 Identity = 170/710 (23.94%), Postives = 304/710 (42.82%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDAD-----DLPFGVESY--EIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVD-GGKPPRKGKTKII--LKVLDENDCEPQF------SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQL-SQTLHGVALKLISKL-----DYETINKYSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQY-ARIYINEGTTKDMVIC---------LVKVTDD----DNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI-VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVP-VRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKP---QVKA-VNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDY-----FSLTPDYGMLCAMEKL 2417
NDN+P +P+ ++ E + + + I A DAD DL + + Y ++ + E F++ D+ L ++ +D E + + A+D + +T + L++LD ND P F + I ++ G + H+ D+DSG+NG+++ T + + F++ SQT G+ ++L+ L D E +++ + AKD GQP P+ S+ + + V +++PP + + I + + ++ + T K + V +D D Q IT + +ES L NR++ S + R + ++ DT Q + + + D+NDN+P F YG+ V EN ++ ++A+D DEG N + Y I+ ++ N FSID ++G + + LD E+ +++I A D G P R + + V+D NDN P LS Y+ + E+ P+GT V +++ D D +N + + F ID +SG I T LDRE+ + F ++A+ D G+ R + + V +N+LD NDN P + + P QV A + P + +K +D D G N+++ ++ + F + P G L A + L
Sbjct: 1479 NDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRM------DSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEI---TGGNGEGRFRINSQT--GI-IELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSI-------GDTSN-GQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHT----VVASDLDEGPNADLIYSITG--GNLGNKFSIDSSSGEL-SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARL------------VYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLAT-----DGGRYEVR----SATVPVQINVLDINDNRP--IFERYPYIGQVPALIQPGQTLLKVQA----------------LDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSL 2122 HSP 6 Score: 101.293 bits (251), Expect = 3.745e-21 Identity = 129/520 (24.81%), Postives = 215/520 (41.35%), Query Frame = 3
Query: 687 IEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDN--------QADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSS---PRYYGIVKE-NRVNEIVTINKDPIL--ATDKD-EGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVS---IEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPM 2192
I L+A P ++++++ DEND P+FSQ + + E G + + D D+G+N ++ + N D N F + G+ I LD E + Y ++A D G P + TA + V + +VND N+P + ++E T VI + D D A+S T +IE + F L+ VL+ R YE++ + + D ++ SD + L V + D NDNAPVF + P Y+ I+ + ++E ++++ D + ATD D EG N V Y +++ + FS+ + GVV + + + I AKD G P SS L V D + + + Y ++ E P+G+ V ++ D + G + A ++ +S I LDRE + ++ S+P +G L + ISV + ILD NDN P+
Sbjct: 2288 IRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDG-NHD--NAFVIEPAFSGIVRTNI-VLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVND----------NQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAES-TVDIE-NMSIFALDRYSGKLVLKRRLDYELQQEYELD----------VIASDAAH----EARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY----IIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIA--------------GNEESAFELL----QSKAIVLVKPLDRERNDLYKLRLVLSHP----HGPPLISSLNSSSGISVIITILDANDNFPI 2751 HSP 7 Score: 94.3597 bits (233), Expect = 4.921e-19 Identity = 188/828 (22.71%), Postives = 321/828 (38.77%), Query Frame = 3
Query: 126 VEITETTVSLFELADVSDHIGRSGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREE--------YCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTF-PEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKP-PRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQ-PPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFY-LNALKTNAVLE---NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPV--FSSPRYYGIVKEN-----RVNEIVTI----------------NKDPILATDKDEGE-----------------------NGTVEYYISNVVDDMKNY--FSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNE-SGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKL 2417
+++T ++ E A++S I +G+ +D F++ +Q G +T R DRE Y +N+ T +S + IG SN I I V D+NDNSP F P Y + ENS+ I +A D D+ P Y I N + F + + +DRE R + A D G+P R+G I + V D+ND P+F Y ++E G ++ + D D G N ++ + A+ T +Q + + + KLD E Y+F ++A D G+ RS+T V++ V ++ND N+PI ++Y YI + V L++ + ++ ++ + E Y LNA + + N T + + E+ L + +V D +G +E++I + PV F + Y ++KEN R+ ++V + N+D IL+ D GE G +Y + + + S + + L + + + + A+ P +S +L++ ++D NDN P+ + + E GT+V +V+ D D N + D F I+ SG + T +VLDRE+ IIA+ D G T ++ V I+D NDN P + V E+ + TS + N + T+P + L ++ V ++N F+L G L +L
Sbjct: 1739 LQVTAKSLHGAENANLSYEI-PAGVANDLFHVD-----WQ--RGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDEGPNADLIYSITGGN---------LGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQ------WQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDIND----------NRPIFERYP--YIGQ------VPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARD-KGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHI-----------VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIAT-----DEGVPQM-----TGTATIRVQIVDVNDNQPTFPPNNLVTVSEAT-ELGAVITSISAN----DVDTYPALTYRL----GAESTVDIENMSIFALDRYSGKLVLKRRL 2493 HSP 8 Score: 89.7373 bits (221), Expect = 1.263e-17 Identity = 156/630 (24.76%), Postives = 259/630 (41.11%), Query Frame = 3
Query: 612 TEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKT-KIILKVLDENDCEPQFSQLIYEIKIKESEMTGLE--LLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS--QTLHGVA---LKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE--GTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF--------SSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNV-VDDMKNYFSI---DKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN--PLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM----KNNDYFSLTPDYGMLCAMEKL 2417
T+ +D + K ++DRE R ++L+A+ P G+ ++++ V DEND P F Q I+ E+ ++ LL R D + N + +I + ++ + F+LS + GV L++ LD ET YS + A D G PP V + + +VND+ P +F Q S+ +A + N GT+ V D++ + ++ +E + +T A+ N+ +DF ETK LH + +V D G L+ T + + + D+NDN P +SP+ I + + E V I D D EY NV ++ +F++ D + +V L LD E + + ++ + A D G P +S + + + D NDN PE + Y + E GT V +V D+D +N+ + T + Q F ID ++G I T+ +D E ++A + PL + +V V I D NDN P+ + SF S EN C+ D D G N+ V T+ K+ F + G +C +L
Sbjct: 121 TDLAIDRATGEIRTKVKLDRE--TRASYSLVAI-----PLSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNI-----VSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQ-----SRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINK-------ALDF--ETKELHELVVVAKD-HGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPK---ISESAQPGEFVA----RISVHDPDS----KTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAE---------TPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPL------------SSTATVLVTIHDVNDNEPIF-------------DQSFYNVSVAENEPVGRCI-LKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGEL 675 HSP 9 Score: 89.7373 bits (221), Expect = 1.386e-17 Identity = 164/742 (22.10%), Postives = 296/742 (39.89%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL--MTEDFV------DNKQPILIVKHQIDREFID--RIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKIS---INFASSTNQDIQNTFQLSQ--TLHGVALKLISKLDYETINKYSFNLVAKDFGQ--PPRSSTAL-VEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGT-TKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTN-KLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYI-SNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLG--VPVRSSSVK---------------------LIVNVKDTNDNQPEVD-LSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND--YFSLTPDYGMLCAMEKLPP--IGDYKTVIVAEDGDFNNSRKQEFLINIHI 2510
NDN PTF + + E++ + + + + P V +E+ E+ V + L +T+D + D L+V +DRE R+E + P+ + ++V D ND P++ Q ++++ E+ G + + D D+G NG + I + N+ + L + +L G AL L + LD+E + +Y + A D R T++ V + + + ND P+ F N K A ++I++ T ++V +V V +D +T EI ++E K+ ++ D ++ + F I+ + G + K+++ L +I++ ++N P F Y + EN + + + A EN + Y I + V +D+ F +D G++ T D E + + +D + SS+V+ + + V D NDN PE S Y + EN G + V +D D N I + G LG F+ID+ SG++ + LDRE S+ I AS D G+ RQ ++T+ + D+NDN+P L T + + P VD D G N+++ ++ N F++ G++ + KL Y +++A DG R + I++
Sbjct: 1359 NDNRPTFTSSSLVFRVREDAALGHVVG---SISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTG-ALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPH--FVSPNSSGGKT-ASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATE-DVEKGGR---FNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQ---VTAKSLHGAENANLSYEIPAGVANDL---FHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDEGPNADLIYS-----ITGGNLGNK------FSIDSSSGELSARP-LDREQHSRYTLQIQAS-----DRGQPKSRQ----GHCNITIFVEDQNDNAPRFKLSK--------------YTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINV 2047 HSP 10 Score: 87.4261 bits (215), Expect = 6.182e-17 Identity = 147/581 (25.30%), Postives = 246/581 (42.34%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLP-----FGVES-YEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEP---------QFSQLIYEIKIKESEMTGLELLHLRVEDKDS-GNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLD--YETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEG-----INQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIV----TINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEK-IKHVSIEISAKDLGVPVRSSSVK-LIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN 2087
NDN PTFP + E +++ + I+ A D D P G ES +IE N ++ +D L++K ++D E E +IA D + +T + ++V DEND P F+ L +I ES +LL + D DS GNN K+ + Q F + + +GV +S+L + Y ++AKD G+P S+ L+ V ND+ QF + QY R I+E V+ + + D I ++ES + +L+++ +K DRE L+ + +V S G + + I D NDN P+F Y E ++E+ +I + + D++ N V Y I++ D+ + F+ID TGV+ LDY+ K + I A D S++ + + D NDN+P+ L+ Y L ENEP+G+ V + + +D D ++ P P+ +S ++F +D+ESG + + V D E + ++AS+
Sbjct: 2422 NDNQPTFPPNNLVT-VSEATELGAVITSISANDVDTYPALTYRLGAESTVDIE----NMSIFA-------LDRYSGKLVLKRRLDYELQQEYELDVIASDAA---HEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYII-----EPAQEGFSVHPS-NGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRV---QANDNGSG--RSQF---LQNQY-RAQISEAAPLGSVVLQLG----QDALDQSLAIIAGNEESAF-------ELLQSKAIVLVKP---LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKY----EAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDE--HMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLD----KGPFGQLNYSIGPAPSDESSW---KMFRVDSESGLVTSAFVFDYEQRQRYDMELLASD 2945 HSP 11 Score: 75.8702 bits (185), Expect = 2.531e-13 Identity = 107/394 (27.16%), Postives = 163/394 (41.37%), Query Frame = 3
Query: 1320 NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEY-YISNVVDDMKNYFSIDKNTGVVKTILG----LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP---MMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND-YFSLTP-DYGMLCAMEKLPP----IGDYKTVIVAED 2459
+R T EI++K+ DRET+ + S+V G N ++ V +KD NDNAP F + EN E + + + A D D T Y +S V+D S + GV+ L LD E S+ I A D G P + + + ++D NDNQP + S Y + EN +GT V +V +D D D N + +Q+F ID +G IY LD E ++A KD Q +T V++ + D NDN P ++ L D +P++S E+ P V + + E + V VT+ D +F+LT D + + LP + +Y +VA D
Sbjct: 126 DRATGEIRTKVKLDRETRASY--SLVAIPLSGRNI-----RVLVTVKDENDNAPTFPQTSMHIEFPENTPRE---VKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRR---------QSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVA---------KDHGEQPLETTAF-VSIRVTDVNDNQPTINVIFLSDD-----ASPKIS-------ESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATD 478 HSP 12 Score: 73.559 bits (179), Expect = 1.280e-12 Identity = 103/419 (24.58%), Postives = 169/419 (40.33%), Query Frame = 3
Query: 699 LIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTAL------VEVFVTNVNDSPPNIVFYQFNKPISKQYAR--IYINEGTTKDMVICLVKVTDDDNQADSITCEI-----ETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNY--FSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENE--PIGTYVGKVNVTDKDT 1904
+IA D GKP K T + ++ D QF Q Y +I E+ G +L L + D S+ + + + F+L L A+ L+ LD E + Y LV PP S+ V + + + ND N PI + A+ I+E I ++ D D Q ++ E+ + E + L T + N +++D+D K+ + C D+ L + + D NDN P F Y + EN E V + A+D D+G G + Y I D ++ F +D +G+V + DYE+ + +E+ A D+G + +SV + V ++ ++ P+ Y F L P G VG+V TD D+
Sbjct: 2618 IIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQ------SLAIIAGNEE---SAFEL---LQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDAND----------NFPIFDRSAKYEAEISELAPLRYSIAQLQAIDAD-QENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVN-------NRLDYDSGAKSYELIIRAC-DSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAEN---EPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG--GKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDS 3000 HSP 13 Score: 69.707 bits (169), Expect = 1.623e-11 Identity = 115/504 (22.82%), Postives = 205/504 (40.67%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQI--DREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS--ITCEIETSQESFYLNALKTNAVLE---NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIE-ISAKDLGVP-----VRSSSVKLIVNVKDTNDNQPEVDLSF-YSFELYENEPIGTYVGKVNVTDKD 1901
NDNSP F +K + + E + + ++ A+D+D Y I N + FV IV+ I DRE D + +IA D G P G I ++++D ND +P F + SE T L + + D ++ + + DI+N + + L L +LDYE +Y +++A D R+ ++ V V + ND+ P + Q + A I+E + D + V TD D++ ++ + IE +QE F ++ +N V+ +R + S D+ FV I+ D G LK + L V D F +Y + E P+ + G++ ++ ++ + + ++ F + ++ +V + LD E+ + + + G P SS + +I+ + D NDN P D S Y E+ E P+ + ++ D D
Sbjct: 2316 NDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHD---------NAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPP---NNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEART---VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVH--PSNGVVSVNMSRLQPAVSSSGDY--------FVRIIAKDA-GKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISE----------AAPLGSVVLQLGQDA-LDQSLAIIAGNEESAFELLQSKAIV-LVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDAD 2781
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304900) HSP 1 Score: 167.933 bits (424), Expect = 1.675e-41 Identity = 136/492 (27.64%), Postives = 227/492 (46.14%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQL-SQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN+P F + + +LEN + I AYD+D+ +Y I + ++NF + VD + + +DRE R F ++A DGG PP+ + +++ V D ND +P F+ YE + E + G + + D D + I T + + F + SQ G+ + + LDY+ ++ + A D G RS TA V + +T+ N+ P +F N P S + E + +V TD D + +I S +N L + N +T I + DRET + + +++ D G L T +E+ + D+NDNAP F SP Y + E+ +V + + A+D D G NG ++Y +S+ D F ID +G ++T GLD E + + A D G P SS+V++ + ++D ND+ P + + EN P+G+ VG+++ D D
Sbjct: 683 NDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLA--------VDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEI-----TTGNTRGRFAITSQNGRGL-ITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAP--IFE--NAPYSAS-----VFEDAPVGTTVLVVSATDSDV---GVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDG-GNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED---ALVGTSVIQVAASDPDVGLNGRIKYLLSDR-DIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPD 1141 HSP 2 Score: 165.236 bits (417), Expect = 1.063e-40 Identity = 144/505 (28.51%), Postives = 225/505 (44.55%), Query Frame = 3
Query: 435 DNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTN-----QDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPP---RSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE---GTTKDMVICLVKVTDDD---NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTD 1907
+ SP F + Y +LE + ++ A D +D P V + + FK VD++ ++ +DRE +D F ++A D PPR G T + + VLD ND P F +E I+E G ++ LR D+D G N +I + T+ QD + + GV + S LD ET + Y + A D R++TA V+V V + ND+ P QF S++ + + E G T+D + ++ TD D N A +Q F ++++ + L YE + ++ + G T +L V + D NDNAP F + ++ V EN V N + A D DEG N + Y IS D+ ++D TG V+TI LD E+ + ++ AKD GVP +S+S +++ V+D NDN P + +Y + E++P GT V V TD D D
Sbjct: 354 NQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP--VVYSMVSLLDSRSQSLFK------VDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV-ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYP-----QF----SERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYE-----------SVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVP---VGYNIIRVQAYDSDEGANAEITYSISERDDNFP--LAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDED 824 HSP 3 Score: 164.851 bits (416), Expect = 1.458e-40 Identity = 157/597 (26.30%), Postives = 259/597 (43.38%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF-VDNKQPILIVKHQIDREFIDRIEFTLIAVD---GGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLE---LLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNT--GVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN-PNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
ND+SPTF + + I E + + S + A D D Y IE + + F +D++ ++ + +DRE D + A D R + +KVLD+ND PQFS+ Y +++ E + G E + H+R D D GNN I Q Q S + L+ LDYE++ Y + A+D G P RS+T + V V + ND+ P QF + + + Y I V+ D D A++ IT I ++F L + +T +++ DRE + +V D G+ ++ + + ++D+NDN P F +P+YY E V E T D E+ + Y I+ + + F+I G++ LDY++ K + ++A D G RS + + +N+ D N+ P + + YS ++E+ P+GT V V+ TD D +N + + + G LG+ P F+I+ ++G I T LDRE +S + A + NP DT ++ + V D NDN+P
Sbjct: 458 NDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS-----QFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGY---------NIIRVQAYDSDEGANAEITYSISERDDNFPLAV--------DPRTGWVQTIKPLDREEQGRFAFQVVAKDG-GVPPKSASSSVVITVQDVNDNDPAF-NPKYY----EANVGEDQPPGTPVTTVTATDPDEDSRLHYEIT--TGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESING--LGSPDP----FSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNP---------SLSDTTDVEIGVT--DVNDNAP 1005 HSP 4 Score: 93.2041 bits (230), Expect = 1.258e-18 Identity = 89/355 (25.07%), Postives = 153/355 (43.10%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED-FVDNKQPILIVKHQ-IDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQN-TFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF 1487
N+ +P F Y + E++ + + + + A D+D GV + NE + L + D F N Q IV + +DRE T+ A DGG P T + + V D ND P F +Y+ I E + G ++ + D D G NG+I +++DI++ +F + T ++ LD E++ + +A D G PP SST V++ + +VNDSPP + +Y+ E + V+ + D D +++ + +L T E R +++D++ K V S L+ +E+++ D+NDNAPV
Sbjct: 891 NNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD---VGVNAQITYSLNE--ESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLL---SDRDIEDGSFVIDPT--SGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTF---------ASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSE-RAQLLTMTELDYESTRKRFELVVRAASPP-----LRNDAHIEILVTDVNDNAPVL 1220 HSP 5 Score: 72.0182 bits (175), Expect = 3.267e-12 Identity = 64/239 (26.78%), Postives = 101/239 (42.26%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQ 1133
NDN+P F Y ILE++ + + + A D D G Y + + ED +D + +DRE + T IAVD G PP ++ +++ D ND P F+ + + E+ G + + D D G N + S D N F L +L+ ++LDYE+ K F LV + PP + A +E+ VT+VND+ P + +Q
Sbjct: 1001 NDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRD----------IEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHY---SIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRA-ASPPLRNDAHIEILVTDVNDNAPVLRDFQ 1224
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0339463) HSP 1 Score: 167.548 bits (423), Expect = 1.940e-41 Identity = 136/492 (27.64%), Postives = 227/492 (46.14%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQL-SQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN+P F + + +LEN + I AYD+D+ +Y I + ++NF + VD + + +DRE R F ++A DGG PP+ + +++ V D ND +P F+ YE + E + G + + D D + I T + + F + SQ G+ + + LDY+ ++ + A D G RS TA V + +T+ N+ P +F N P S + E + +V TD D + +I S +N L + N +T I + DRET + + +++ D G L T +E+ + D+NDNAP F SP Y + E+ +V + + A+D D G NG ++Y +S+ D F ID +G ++T GLD E + + A D G P SS+V++ + ++D ND+ P + + EN P+G+ VG+++ D D
Sbjct: 683 NDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLA--------VDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEI-----TTGNTRGRFAITSQNGRGL-ITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAP--IFE--NAPYSAS-----VFEDAPVGTTVLVVSATDSDV---GVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDG-GNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED---ALVGTSVIQVAASDPDVGLNGRIKYLLSDR-DIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPD 1141 HSP 2 Score: 164.851 bits (416), Expect = 1.200e-40 Identity = 144/505 (28.51%), Postives = 225/505 (44.55%), Query Frame = 3
Query: 435 DNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTN-----QDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPP---RSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE---GTTKDMVICLVKVTDDD---NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTD 1907
+ SP F + Y +LE + ++ A D +D P V + + FK VD++ ++ +DRE +D F ++A D PPR G T + + VLD ND P F +E I+E G ++ LR D+D G N +I + T+ QD + + GV + S LD ET + Y + A D R++TA V+V V + ND+ P QF S++ + + E G T+D + ++ TD D N A +Q F ++++ + L YE + ++ + G T +L V + D NDNAP F + ++ V EN V N + A D DEG N + Y IS D+ ++D TG V+TI LD E+ + ++ AKD GVP +S+S +++ V+D NDN P + +Y + E++P GT V V TD D D
Sbjct: 354 NQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP--VVYSMVSLLDSRSQSLFK------VDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV-ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYP-----QF----SERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYE-----------SVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVP---VGYNIIRVQAYDSDEGANAEITYSISERDDNFP--LAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDED 824 HSP 3 Score: 164.466 bits (415), Expect = 1.675e-40 Identity = 157/597 (26.30%), Postives = 259/597 (43.38%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF-VDNKQPILIVKHQIDREFIDRIEFTLIAVD---GGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLE---LLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNT--GVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN-PNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
ND+SPTF + + I E + + S + A D D Y IE + + F +D++ ++ + +DRE D + A D R + +KVLD+ND PQFS+ Y +++ E + G E + H+R D D GNN I Q Q S + L+ LDYE++ Y + A+D G P RS+T + V V + ND+ P QF + + + Y I V+ D D A++ IT I ++F L + +T +++ DRE + +V D G+ ++ + + ++D+NDN P F +P+YY E V E T D E+ + Y I+ + + F+I G++ LDY++ K + ++A D G RS + + +N+ D N+ P + + YS ++E+ P+GT V V+ TD D +N + + + G LG+ P F+I+ ++G I T LDRE +S + A + NP DT ++ + V D NDN+P
Sbjct: 458 NDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS-----QFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGY---------NIIRVQAYDSDEGANAEITYSISERDDNFPLAV--------DPRTGWVQTIKPLDREEQGRFAFQVVAKDG-GVPPKSASSSVVITVQDVNDNDPAF-NPKYY----EANVGEDQPPGTPVTTVTATDPDEDSRLHYEIT--TGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESING--LGSPDP----FSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNP---------SLSDTTDVEIGVT--DVNDNAP 1005 HSP 4 Score: 92.8189 bits (229), Expect = 1.359e-18 Identity = 89/355 (25.07%), Postives = 153/355 (43.10%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED-FVDNKQPILIVKHQ-IDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQN-TFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF 1487
N+ +P F Y + E++ + + + + A D+D GV + NE + L + D F N Q IV + +DRE T+ A DGG P T + + V D ND P F +Y+ I E + G ++ + D D G NG+I +++DI++ +F + T ++ LD E++ + +A D G PP SST V++ + +VNDSPP + +Y+ E + V+ + D D +++ + +L T E R +++D++ K V S L+ +E+++ D+NDNAPV
Sbjct: 891 NNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD---VGVNAQITYSLNE--ESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLL---SDRDIEDGSFVIDPT--SGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTF---------ASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSE-RAQLLTMTELDYESTRKRFELVVRAASPP-----LRNDAHIEILVTDVNDNAPVL 1220 HSP 5 Score: 72.0182 bits (175), Expect = 3.410e-12 Identity = 64/239 (26.78%), Postives = 101/239 (42.26%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQ 1133
NDN+P F Y ILE++ + + + A D D G Y + + ED +D + +DRE + T IAVD G PP ++ +++ D ND P F+ + + E+ G + + D D G N + S D N F L +L+ ++LDYE+ K F LV + PP + A +E+ VT+VND+ P + +Q
Sbjct: 1001 NDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRD----------IEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHY---SIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRA-ASPPLRNDAHIEILVTDVNDNAPVLRDFQ 1224
BLAST of Protocadherin-1 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304899) HSP 1 Score: 167.548 bits (423), Expect = 2.073e-41 Identity = 136/492 (27.64%), Postives = 227/492 (46.14%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQL-SQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN+P F + + +LEN + I AYD+D+ +Y I + ++NF + VD + + +DRE R F ++A DGG PP+ + +++ V D ND +P F+ YE + E + G + + D D + I T + + F + SQ G+ + + LDY+ ++ + A D G RS TA V + +T+ N+ P +F N P S + E + +V TD D + +I S +N L + N +T I + DRET + + +++ D G L T +E+ + D+NDNAP F SP Y + E+ +V + + A+D D G NG ++Y +S+ D F ID +G ++T GLD E + + A D G P SS+V++ + ++D ND+ P + + EN P+G+ VG+++ D D
Sbjct: 683 NDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLA--------VDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEI-----TTGNTRGRFAITSQNGRGL-ITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAP--IFE--NAPYSAS-----VFEDAPVGTTVLVVSATDSDV---GVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDG-GNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILED---ALVGTSVIQVAASDPDVGLNGRIKYLLSDR-DIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPD 1141 HSP 2 Score: 164.851 bits (416), Expect = 1.239e-40 Identity = 144/505 (28.51%), Postives = 225/505 (44.55%), Query Frame = 3
Query: 435 DNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTN-----QDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPP---RSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE---GTTKDMVICLVKVTDDD---NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTD 1907
+ SP F + Y +LE + ++ A D +D P V + + FK VD++ ++ +DRE +D F ++A D PPR G T + + VLD ND P F +E I+E G ++ LR D+D G N +I + T+ QD + + GV + S LD ET + Y + A D R++TA V+V V + ND+ P QF S++ + + E G T+D + ++ TD D N A +Q F ++++ + L YE + ++ + G T +L V + D NDNAP F + ++ V EN V N + A D DEG N + Y IS D+ ++D TG V+TI LD E+ + ++ AKD GVP +S+S +++ V+D NDN P + +Y + E++P GT V V TD D D
Sbjct: 354 NQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP--VVYSMVSLLDSRSQSLFK------VDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV-ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYP-----QF----SERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYE-----------SVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVP---VGYNIIRVQAYDSDEGANAEITYSISERDDNFP--LAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDED 824 HSP 3 Score: 164.466 bits (415), Expect = 1.805e-40 Identity = 157/597 (26.30%), Postives = 259/597 (43.38%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF-VDNKQPILIVKHQIDREFIDRIEFTLIAVD---GGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLE---LLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNT--GVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN-PNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
ND+SPTF + + I E + + S + A D D Y IE + + F +D++ ++ + +DRE D + A D R + +KVLD+ND PQFS+ Y +++ E + G E + H+R D D GNN I Q Q S + L+ LDYE++ Y + A+D G P RS+T + V V + ND+ P QF + + + Y I V+ D D A++ IT I ++F L + +T +++ DRE + +V D G+ ++ + + ++D+NDN P F +P+YY E V E T D E+ + Y I+ + + F+I G++ LDY++ K + ++A D G RS + + +N+ D N+ P + + YS ++E+ P+GT V V+ TD D +N + + + G LG+ P F+I+ ++G I T LDRE +S + A + NP DT ++ + V D NDN+P
Sbjct: 458 NDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS-----QFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGY---------NIIRVQAYDSDEGANAEITYSISERDDNFPLAV--------DPRTGWVQTIKPLDREEQGRFAFQVVAKDG-GVPPKSASSSVVITVQDVNDNDPAF-NPKYY----EANVGEDQPPGTPVTTVTATDPDEDSRLHYEIT--TGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESING--LGSPDP----FSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNP---------SLSDTTDVEIGVT--DVNDNAP 1005 HSP 4 Score: 92.8189 bits (229), Expect = 1.440e-18 Identity = 89/355 (25.07%), Postives = 153/355 (43.10%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED-FVDNKQPILIVKHQ-IDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQN-TFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVF 1487
N+ +P F Y + E++ + + + + A D+D GV + NE + L + D F N Q IV + +DRE T+ A DGG P T + + V D ND P F +Y+ I E + G ++ + D D G NG+I +++DI++ +F + T ++ LD E++ + +A D G PP SST V++ + +VNDSPP + +Y+ E + V+ + D D +++ + +L T E R +++D++ K V S L+ +E+++ D+NDNAPV
Sbjct: 891 NNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSD---VGVNAQITYSLNE--ESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLL---SDRDIEDGSFVIDPT--SGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTF---------ASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSE-RAQLLTMTELDYESTRKRFELVVRAASPP-----LRNDAHIEILVTDVNDNAPVL 1220 HSP 5 Score: 72.0182 bits (175), Expect = 3.525e-12 Identity = 64/239 (26.78%), Postives = 101/239 (42.26%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQ 1133
NDN+P F Y ILE++ + + + A D D G Y + + ED +D + +DRE + T IAVD G PP ++ +++ D ND P F+ + + E+ G + + D D G N + S D N F L +L+ ++LDYE+ K F LV + PP + A +E+ VT+VND+ P + +Q
Sbjct: 1001 NDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRD----------IEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHY---SIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRA-ASPPLRNDAHIEILVTDVNDNAPVLRDFQ 1224
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 233.417 bits (594), Expect = 1.593e-62 Identity = 203/703 (28.88%), Postives = 328/703 (46.66%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI--VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN---NDYFSLTPDYGMLCAMEKLP--PIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP + EN+ + + S+P+A D D GV Y + E ++ + ED + K P LIV +DRE D + T+ AVDGG PPR + + + D ND P+F + YE ++ E+ G +L ++ D D G NG+I + + + ++ ++ + +K LD E IN F +VA+D G P+SS V + VT+ ND+ P + ++ I+E + LV+V+D D +++ + F L ++V +N++ Y +++ D E + V IV D+ G L TN L+V + D NDN+P+F SP + + +EN+ E V ++A+D D G N + Y I + D + F ID N+G V+ LD E ++A D GVP + +++ V D NDN P+ LS YSF + EN P + VG V V D D N + + P +G F I N +G I + + DRE S F + A + G D R + + VT+N+LD+NDN+P++ KP SFI+ S P++ V D+D G N+++ ++ +D F ++P G + ++L G ++ VI D SR L++I++ E
Sbjct: 125 NDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGE-KLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDP-VPKLLRIDRSSGIIYVK--GPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGL-VTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSV-DNKRKYFLQTTTPLDYERVRDYRVEIVAVDS-GNPALSSTNSLKVQVTDTNDNSPIF-SPTLFEVEFAEENQPGEKVV----EVVASDADSGTNAELVYSI--IADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVE------PDVGK-------FVIQNGTGTILSSISFDREKESSYTFRLKAVD------GGDPPR----SSYVGVTINVLDENDNAPVVT---KPS------NSSFIRLSP--MAAPDSVVEV-VEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSD-RGKPSRHAIALVHIYVNE 777 HSP 2 Score: 119.783 bits (299), Expect = 7.096e-27 Identity = 141/557 (25.31%), Postives = 225/557 (40.39%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYIS------------NVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++V D ND PQF + + + E+ G DKD+ NG + Q+++ +LI LD E + Y + A D G PPR S+AL+ V + + ND+ P K + E + + VK D D + EIE + K + + +K +D + E L F V + +G + + + + D NDNAP R G+V + + + I++D + T DKDEGEN V ++ + VD+ + YF ++T LDYE+++ +EI A D G P SS+ L V V DTNDN P + + E E G V +V +D D+ N + + ++ +F ID SG++ + LDRE + F + A+ D G R +V + +LD+NDN P ML S S EN+ P + V D+DEGEN++V+++++
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPK---------FEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNG---EIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDRE-EINNLKF--YVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEI-RGIGLVTHS--DGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYF--------LQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVY----------SIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAA-----DKGVPSHRG-----TATVVIKVLDRNDNDPKFML-------------SGYSFSVLENMPPLSPVGM-VTVQDMDEGENAQVQLSVE 615 HSP 3 Score: 94.3597 bits (233), Expect = 5.177e-19 Identity = 97/332 (29.22%), Postives = 145/332 (43.67%), Query Frame = 3
Query: 1419 NQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNY---FSIDKNTGVVKTI-LG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTN-ENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSLTP 2384
NQ + + + ++DINDN P F SP V EN + + +I LATDKD NG +Y ++ + + + + D+ + + I LG LD E + I A D G P R SS L V + D NDN P+ + S Y E+ EN PIG V +V D D N + + + P P L ID SG IY K LDRE + + F ++A + P + V++++ D+NDN+P + ++ + + S NI + V V D DEGEN+ V + + F L P
Sbjct: 109 NQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIP----LATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKL---------LRIDRSSGIIYVKGPLDREEINNLKFYVVARDKGPSPKSSKTY----------VSIDVTDQNDNAPAVEIRG----------IGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRP 407
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 231.106 bits (588), Expect = 4.576e-62 Identity = 203/703 (28.88%), Postives = 327/703 (46.51%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI--VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN---NDYFSLTPDYGMLCAMEKLPP--IGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP + EN+ + + S+P+A D D GV Y + E ++ + ED K P LIV +DRE D + T+ AVDGG PPR + + + D ND P+F + YE ++ E+ G +L ++ D D G NG+I + + + ++ ++ + +K LD E IN F +VA+D G P+SS V + VT+ ND+ P + ++ I+E + LV+V+D D +++ + F L ++V +N++ Y +++ D E + V IV D+ G L TN L+V + D NDN+P+F SP + + +EN+ E V ++A+D D G N + Y I + D + F ID N+G V+ LD E ++A D GVP + +++ V D NDN P+ LS YSF + EN P + VG V V D D N + + P +G F I N +G I + + DRE S F + A + G D R + + VT+N+LD+NDN+P++ KP SFI+ S P++ V D+D G N+++ ++ +D F ++P G + ++L G ++ VI D SR L++I++ E
Sbjct: 125 NDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDR-GEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDP-VPKLLRIDRSSGIIYVK--GPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGL-VTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSV-DNKRKYFLQTTTPLDYERVRDYRVEIVAVDS-GNPALSSTNSLKVQVTDTNDNSPIF-SPTLFEVEFAEENQPGEKVV----EVVASDADSGTNAELVYSI--IADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVE------PDVGK-------FVIQNGTGTILSSISFDREKESSYTFRLKAVD------GGDPPR----SSYVGVTINVLDENDNAPVVT---KPS------NSSFIRLSPMA--APDSVVEV-VEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSD-RGKPSRHAIALVHIYVNE 777 HSP 2 Score: 117.472 bits (293), Expect = 3.630e-26 Identity = 145/569 (25.48%), Postives = 226/569 (39.72%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYIS------------NVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYG 2393
++V D ND PQF + + + E+ G DKD+ NG + Q+++ +LI LD E + Y + A D G PPR S+AL+ V + + ND+ P K + E + + VK D D + EIE + K + + +K +D + E L F V + +G + + + + D NDNAP R G+V + + + I++D + T DKDEGEN V ++ + VD+ + YF ++T LDYE+++ +EI A D G P SS+ L V V DTNDN P + + E E G V +V +D D+ N + + ++ +F ID SG++ + LDRE + F + A+ D G R +V + +LD+NDN P ML S S EN+ P + V D+DEGEN++V+ S+ PD G
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPK---------FEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNG---EIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDRE-EINNLKF--YVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEI-RGIGLVTHS--DGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYF--------LQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVY----------SIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAA-----DKGVPSHRG-----TATVVIKVLDRNDNDPKFML-------------SGYSFSVLENMPPLSPVGM-VTVQDMDEGENAQVQ--------LSVEPDVG 619 HSP 3 Score: 92.8189 bits (229), Expect = 1.457e-18 Identity = 95/332 (28.61%), Postives = 144/332 (43.37%), Query Frame = 3
Query: 1419 NQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNY---FSIDKNTGVVKTIL--GLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTN-ENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSLTP 2384
NQ + + + ++DINDN P F SP V EN + + +I LATDKD NG +Y ++ + + + + D+ + + I+ LD E + I A D G P R SS L V + D NDN P+ + S Y E+ EN PIG V +V D D N + + + P P L ID SG IY K LDRE + + F ++A + P + V++++ D+NDN+P + ++ + + S NI + V V D DEGEN+ V + + F L P
Sbjct: 109 NQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIP----LATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKL---------LRIDRSSGIIYVKGPLDREEINNLKFYVVARDKGPSPKSSKTY----------VSIDVTDQNDNAPAVEIRG----------IGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRP 407
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh7b (protocadherin 7b [Source:ZFIN;Acc:ZDB-GENE-081104-299]) HSP 1 Score: 217.624 bits (553), Expect = 2.512e-57 Identity = 180/629 (28.62%), Postives = 287/629 (45.63%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPN----------------------ENFD------VYFKLMTEDFVDN-KQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTK-------DMVICLVKVTDDDNQADSI-TCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV--NEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMML 2201
NDN+P+FP + EN I + LP A D D G+E YE+ + N FD F+L D D KQP LI+K +DRE D E TL DGG PPR + + + + D ND P+F + +YE + E+ G +L L+ D D G NG+I F ++T + ++ +L ++ L ++ ++D E +++ F ++A+D GQPP++ A V + + + ND+ PNI ++ RI++ +G D I LV+V+D D + I TC + F L N+K Y + + D E + V IV D+ + + + V + D+NDN PVFS EN +VT ++A D D G+N + Y + + V+ + FSID +TG ++ LD E+ + ++ AKD G+PV S ++V V D NDN+P+ ++F + EN + VG + V D D N + + + IF+IDN +G I++ + DRE + F + A + G D R T+ +SV +D NDN P ++
Sbjct: 131 NDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPILQLKAGDTDVGVNGQIEYVFGAAT-ESVRRLLRLDESTG--WLSVLHRIDREDVSQLRFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDI--------RKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTV-VGDVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLI-VKVGDMNDNPPVFSKSTVEVSFPENNAPGERVVT-----VVALDADSGKNAEISYSLDSSVNGI---FSIDADTGDIRVNTILDREQTERYEFKVIAKDKGMPVLQGSATVVVLVADKNDNEPKFMQDVFTFYIQENLQPNSPVGMITVMDADKGQNADMSLYI-------------EEEENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVD------GGDPPRSATATVSLSV----MDVNDNPPTVLF 715 HSP 2 Score: 132.109 bits (331), Expect = 1.147e-30 Identity = 139/511 (27.20%), Postives = 233/511 (45.60%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF-----VDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFS-QLIYEIKIKESEMTGLE-------LLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVA--LKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQES-FYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSF---YSFELYENEPIGTYVGKVNVTDKDT 1904
NDN+P F + Y ++ ENS + I + A D GV N + F TE +D L V H+IDRE + ++ FT++A D G+PP+ K +I+ + DEND P + I I +K+ E + ++V D+D G NG ++ ++ ++ ++ L + LDYE + +Y+ +VA D G P SS + V V ++ND+PP VF + +S + + V+ +V + D + I+ +++S F ++A T +I+ DRE + ++ D +G+ L+ + + V++ D NDN P F + ++EN + N V + I D D+G+N + YI ++ +N FSID NTG + + + D E+ + S + A D G P RS++ + ++V D NDN P V Y+ L + I T V V+ TD DT
Sbjct: 273 NDNTPRFEKSVYEADLPENSSPGAPI---LQLKAGDTDVGV--------NGQIEYVFGAATESVRRLLRLDESTGWLSVLHRIDREDVSQLRFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVGDVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPP--VFSKSTVEVS------FPENNAPGERVVTVVALDADSGKNAEISYSLDSSVNGIFSIDA----------DTGDIRVNTILDREQTERYEFKVIAKD-KGMPVLQGSATVVVLVADKNDNEPKFMQDVFTFYIQENLQPNSPVGM----ITVMDADKGQNADMSLYI----EEEENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGGDPPRSATATVSLSVMDVNDNPPTVLFPMNNSYTL-LPPSSNIRTVVRTVSATDTDT 744 HSP 3 Score: 98.5969 bits (244), Expect = 2.393e-20 Identity = 113/448 (25.22%), Postives = 187/448 (41.74%), Query Frame = 3
Query: 477 ILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLM----TEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSP---RYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDT 1796
+ E+ +++ I+L D D P G+ + + DV F+L E ++ K+ L +D E + ++AVD G P +I+KV D ND P FS+ E+ E+ G ++ + D DSG N +IS + SS N F + + + I LD E +Y F ++AKD G P +A V V V + ND+ P + F YI E + + ++ V D D Q ++ IE + F ++ T I S + FDRE + + + D G T + + + D+NDN P P Y + + + +V + ATD D G N + Y I V + F +D TGV+ + L+ + + + D GVP +S++ + + V +T
Sbjct: 403 VAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVG-----DVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNAPGERVVTVVALDADSGKNAEISYSLDSSVN----GIFSIDADTGDIRVNTI--LDREQTERYEFKVIAKDKGMPVLQGSATVVVLVADKNDNEPKFMQDVFT---------FYIQENLQPNSPVGMITVMDADKGQNADMSLYIEEEENIFSID----------NNTGTIFSNMAFDREQRNNYSFRVKAVDG-GDPPRSATATVSLSVMDVNDNPPTVLFPMNNSYTLLPPSSNIRTVVRT----VSATDTDTGVNANLSYRI--VGGNPFKLFDMDAWTGVISLVGKLEQKHFGLHRLVVQVNDSGVPSQSTTTLVHIYVNET 813
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: pcdh7b (protocadherin 7b [Source:ZFIN;Acc:ZDB-GENE-081104-299]) HSP 1 Score: 216.853 bits (551), Expect = 3.088e-57 Identity = 180/629 (28.62%), Postives = 287/629 (45.63%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPN----------------------ENFD------VYFKLMTEDFVDN-KQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTK-------DMVICLVKVTDDDNQADSI-TCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV--NEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMML 2201
NDN+P+FP + EN I + LP A D D G+E YE+ + N FD F+L D D KQP LI+K +DRE D E TL DGG PPR + + + + D ND P+F + +YE + E+ G +L L+ D D G NG+I F ++T + ++ +L ++ L ++ ++D E +++ F ++A+D GQPP++ A V + + + ND+ PNI ++ RI++ +G D I LV+V+D D + I TC + F L N+K Y + + D E + V IV D+ + + + V + D+NDN PVFS EN +VT ++A D D G+N + Y + + V+ + FSID +TG ++ LD E+ + ++ AKD G+PV S ++V V D NDN+P+ ++F + EN + VG + V D D N + + + IF+IDN +G I++ + DRE + F + A + G D R T+ +SV +D NDN P ++
Sbjct: 131 NDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPILQLKAGDTDVGVNGQIEYVFGAAT-ESVRRLLRLDESTG--WLSVLHRIDREDVSQLRFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDI--------RKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTV-VGDVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLI-VKVGDMNDNPPVFSKSTVEVSFPENNAPGERVVT-----VVALDADSGKNAEISYSLDSSVNGI---FSIDADTGDIRVNTILDREQTERYEFKVIAKDKGMPVLQGSATVVVLVADKNDNEPKFMQDVFTFYIQENLQPNSPVGMITVMDADKGQNADMSLYI-------------EEEENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVD------GGDPPRSATATVSLSV----MDVNDNPPTVLF 715 HSP 2 Score: 131.339 bits (329), Expect = 2.079e-30 Identity = 139/511 (27.20%), Postives = 233/511 (45.60%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF-----VDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFS-QLIYEIKIKESEMTGLE-------LLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVA--LKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQES-FYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSF---YSFELYENEPIGTYVGKVNVTDKDT 1904
NDN+P F + Y ++ ENS + I + A D GV N + F TE +D L V H+IDRE + ++ FT++A D G+PP+ K +I+ + DEND P + I I +K+ E + ++V D+D G NG ++ ++ ++ ++ L + LDYE + +Y+ +VA D G P SS + V V ++ND+PP VF + +S + + V+ +V + D + I+ +++S F ++A T +I+ DRE + ++ D +G+ L+ + + V++ D NDN P F + ++EN + N V + I D D+G+N + YI ++ +N FSID NTG + + + D E+ + S + A D G P RS++ + ++V D NDN P V Y+ L + I T V V+ TD DT
Sbjct: 273 NDNTPRFEKSVYEADLPENSSPGAPI---LQLKAGDTDVGV--------NGQIEYVFGAATESVRRLLRLDESTGWLSVLHRIDREDVSQLRFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVGDVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPP--VFSKSTVEVS------FPENNAPGERVVTVVALDADSGKNAEISYSLDSSVNGIFSIDA----------DTGDIRVNTILDREQTERYEFKVIAKD-KGMPVLQGSATVVVLVADKNDNEPKFMQDVFTFYIQENLQPNSPVGM----ITVMDADKGQNADMSLYI----EEEENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGGDPPRSATATVSLSVMDVNDNPPTVLFPMNNSYTL-LPPSSNIRTVVRTVSATDTDT 744 HSP 3 Score: 97.8265 bits (242), Expect = 4.164e-20 Identity = 113/448 (25.22%), Postives = 187/448 (41.74%), Query Frame = 3
Query: 477 ILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLM----TEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSP---RYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDT 1796
+ E+ +++ I+L D D P G+ + + DV F+L E ++ K+ L +D E + ++AVD G P +I+KV D ND P FS+ E+ E+ G ++ + D DSG N +IS + SS N F + + + I LD E +Y F ++AKD G P +A V V V + ND+ P + F YI E + + ++ V D D Q ++ IE + F ++ T I S + FDRE + + + D G T + + + D+NDN P P Y + + + +V + ATD D G N + Y I V + F +D TGV+ + L+ + + + D GVP +S++ + + V +T
Sbjct: 403 VAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVG-----DVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNAPGERVVTVVALDADSGKNAEISYSLDSSVN----GIFSIDADTGDIRVNTI--LDREQTERYEFKVIAKDKGMPVLQGSATVVVLVADKNDNEPKFMQDVFT---------FYIQENLQPNSPVGMITVMDADKGQNADMSLYIEEEENIFSID----------NNTGTIFSNMAFDREQRNNYSFRVKAVDG-GDPPRSATATVSLSVMDVNDNPPTVLFPMNNSYTLLPPSSNIRTVVRT----VSATDTDTGVNANLSYRI--VGGNPFKLFDMDAWTGVISLVGKLEQKHFGLHRLVVQVNDSGVPSQSTTTLVHIYVNET 813
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 216.468 bits (550), Expect = 3.125e-57 Identity = 194/701 (27.67%), Postives = 322/701 (45.93%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI--VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEKLPP-IGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P F I EN+ + + ++P+A D D G+ Y + E ++ F L D K P LIV +DRE D + + VDGG PPR+ + + + D ND P+F + YE ++ E+ G +L ++ D D G NG+++ + ++ + + + + +K +D E I+ F + AKD G +SS ALV + V + ND+ P+I ++ + I+E + LV+V+D D +++ + F L + RK Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF SP Y + +EN+ + V ++ATD D G N + Y I+ + F I+ NTG V+ + LD E++ H ++A D GVP + ++V V D NDN P+ L+ YSF + EN P + VG V V D D N + + + +P + F I N + I + + DRE S F + A + G D R + + +T+N+LD+NDN+P + K N F+ T+ + E+ D+D G NS++ V + F ++ + + A E P IG ++ V+ +D R+ L++I++ E
Sbjct: 153 NDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNL-FSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSP-VMRLLSIDRNTGIIFVK--GSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGL-VTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRK-YFLQTTTLLDYERIKEYRIEIVAVDS-GNPALSSTNSLKVQVTDMNDNAPVF-SPTLYEVEFFEENQPGDKVL----DVVATDADSGTNAELTYSITG-GSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQL-------------SVEPDNGKFMIQNGTYTILSTISFDREKESTYSFRLKAVD------GGDPPR----SSYVGITINVLDENDNAPYV-------TKPANSSYKFLDPRTSPETHVESVEA-----EDIDIGLNSELDFNIVGGNPHGLFRISSEGEITLAKEFTPKHIGLHRLVVKVKD-KGTPPRQTTALVHIYVNE 804 HSP 2 Score: 140.969 bits (354), Expect = 2.183e-33 Identity = 156/571 (27.32%), Postives = 236/571 (41.33%), Query Frame = 3
Query: 717 GKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHG----VALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
G PR + +I ++LDEND PQFS + + I E+ G D+DSG+NG ++A +T + N F L L ++ LD E + Y N+ D G PPR S+AL+ + +T+ ND+ P + + + E + + VK D D + E+ S ++ ++ N +K +D + E L F V + G + + +KD NDNAP S R GI + + I++D + T D+DEGEN V ++ V D + YF ++T LDYE+IK IEI A D G P SS+ L V V D NDN P + Y E +E G V V TD D+ N + +P + +F I+ +G++ LDRE F + A+ D G R +V V +LD+NDN P ML SF S EN+ P + V + D DEGEN++V+++++
Sbjct: 137 GTGPRLIEGRI--EILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGI--ADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPK---------FERSHYEGELPENSPVGHSVLQVKANDSDMGPNG---EVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDRE-EISILKF--YVQAKDNGPQSKSSKALVTITVKDQNDNAP---SIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYF--------LQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVP----------EGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAA-----DKGVPSLRG-----TATVVVKVLDRNDNDPKFMLNG----------YSF---SVQENMPPLSPVGMVTVN-DHDEGENARVQLSVE 643
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 229.18 bits (583), Expect = 7.412e-61 Identity = 182/651 (27.96%), Postives = 309/651 (47.47%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I +P A D D GV SYE+ E D++ + ED D KQP LIV +DRE D + T+ DGG P R + + +LD ND P+F ++ YE ++ E+ G +L ++ D D G N +I +F +++ ++ L ++ + ++ +D E + F++VAKD G P+++ V + + + ND+ P I F ++ Q I+E + + LV+V+D D ++ + F L + ++ +++K Y +++ D E+ + + IV D+ G L TN L+V + D+NDNAPVFS + EN +N++V + ATD D G N + Y I + D + FSI+ ++G ++ LD E+ +H + A D G+P + +++ V D NDN P+ L+ Y+F + EN P + VG V V D D N + + +P F I N +G I + + DRE S F + A + G D R + + VT+N+LD+NDN+P++++ K + P+ +P V + D+D G N+++ ++ + + F L
Sbjct: 162 NDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAED-QDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQ--GPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGL-VTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQV-SDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDS-GNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVM----EVSATDADSGPNSQLHYSI--LPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHL-------------SVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVD------GGDPPR----SSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQT-----------HPGTPVNW-VRAEDMDTGINAELDYSIASGNPFEL 764 HSP 2 Score: 139.043 bits (349), Expect = 1.333e-32 Identity = 154/561 (27.45%), Postives = 235/561 (41.89%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD-----PIL---ATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++++D ND P F+ + + I E+ G+ D+DSG NG S + Q+ F L Q L ++ LD E + Y + +D G P R+S+AL+ + + + ND+ P K + E + + VK D D + EI+ SF+ + +L +R T I + DRE TL F S+V D +G N ++ + I+D NDN PV R +G+V + I++D P+ +D DEG N V ++ V D K YF ++T LDYE +K +IEI A D G P SS+ L V V D NDN P S EN I V +V+ TD D+ ++LP P+ A IF+I+ +SG+I VLDRE F ++A +D G + T SV + +LD+NDN P ML +F + P VT +D D+GEN+ + ++++
Sbjct: 156 IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELI--VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPK---------FEKMAYEAELPENSPMGHSVLQVKANDSDQ---GVNAEIDY---SFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKF-SVVAKD-KGANPKTARTQVTITIRDTNDNKPVIEI-RGFGLVTHQ--GGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYF--------LQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSG----PNSQLHYSILPDPS------ARGIFSINPDSGQIRVNTVLDREQREHYDFHVVA-----VDKG---IPSLKGTA--SVVITVLDRNDNDPKFMLNG----------YNFSVMENMPRLSPVGMVT----VIDADKGENAHIHLSVE 652 HSP 3 Score: 83.5741 bits (205), Expect = 1.589e-15 Identity = 97/365 (26.58%), Postives = 156/365 (42.74%), Query Frame = 3
Query: 1332 YEIKSKIDFD--RETKTLH-----FVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI------DKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSL 2378
Y ++ ID + RE + L F+ S T+ ++ + + ++ I DINDN P F+SP + EN I + P ATD+D G NG Y + V + ++ F + D+ + + LD E+ + I +D G P R+SS L +++ DTNDN P+ + Y EL EN P+G V +V D D +N + + S ++ +D +G I + +DRE + F+++A D G + T VT+ I D NDN P++ ++ V NI + V P V D+DEG N+ V + + F L
Sbjct: 110 YTTETSIDRESLRECQNLEPGEKCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPEN--TNIGMLFPIPA-ATDRDSGVNGVSSYELI-VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQ---------ASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAK-----DKGAN-----PKTARTQVTITIRDTNDNKPVIEIRGFGLV---------THQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQL 442 HSP 4 Score: 68.1662 bits (165), Expect = 7.044e-11 Identity = 66/230 (28.70%), Postives = 94/230 (40.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYS--FNLVAK--DFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + DAD EN ++ + E + N ++ DRE F L AVDGG PPR + + VLDEND P S + Y+ ++ G + +R ED D+G N ++ + AS N F+L Q H + K I K+ LV K D G+P R TALV ++
Sbjct: 606 NDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADK-------------GENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTH-PGTPVNWVRAEDMDTGINAELDYSIASG------NPFELFQISHNNGEVTLEK---AIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 812
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 228.794 bits (582), Expect = 8.054e-61 Identity = 182/651 (27.96%), Postives = 309/651 (47.47%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I +P A D D GV SYE+ E D++ + ED D KQP LIV +DRE D + T+ DGG P R + + +LD ND P+F ++ YE ++ E+ G +L ++ D D G N +I +F +++ ++ L ++ + ++ +D E + F++VAKD G P+++ V + + + ND+ P I F ++ Q I+E + + LV+V+D D ++ + F L + ++ +++K Y +++ D E+ + + IV D+ G L TN L+V + D+NDNAPVFS + EN +N++V + ATD D G N + Y I + D + FSI+ ++G ++ LD E+ +H + A D G+P + +++ V D NDN P+ L+ Y+F + EN P + VG V V D D N + + +P F I N +G I + + DRE S F + A + G D R + + VT+N+LD+NDN+P++++ K + P+ +P V + D+D G N+++ ++ + + F L
Sbjct: 170 NDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAED-QDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQ--GPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGL-VTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQV-SDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDS-GNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVM----EVSATDADSGPNSQLHYSI--LPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHL-------------SVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVD------GGDPPR----SSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQT-----------HPGTPVNW-VRAEDMDTGINAELDYSIASGNPFEL 772 HSP 2 Score: 138.658 bits (348), Expect = 1.586e-32 Identity = 154/561 (27.45%), Postives = 235/561 (41.89%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD-----PIL---ATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++++D ND P F+ + + I E+ G+ D+DSG NG S + Q+ F L Q L ++ LD E + Y + +D G P R+S+AL+ + + + ND+ P K + E + + VK D D + EI+ SF+ + +L +R T I + DRE TL F S+V D +G N ++ + I+D NDN PV R +G+V + I++D P+ +D DEG N V ++ V D K YF ++T LDYE +K +IEI A D G P SS+ L V V D NDN P S EN I V +V+ TD D+ ++LP P+ A IF+I+ +SG+I VLDRE F ++A +D G + T SV + +LD+NDN P ML +F + P VT +D D+GEN+ + ++++
Sbjct: 164 IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELI--VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPK---------FEKMAYEAELPENSPMGHSVLQVKANDSDQ---GVNAEIDY---SFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKF-SVVAKD-KGANPKTARTQVTITIRDTNDNKPVIEI-RGFGLVTHQ--GGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYF--------LQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSG----PNSQLHYSILPDPS------ARGIFSINPDSGQIRVNTVLDREQREHYDFHVVA-----VDKG---IPSLKGTA--SVVITVLDRNDNDPKFMLNG----------YNFSVMENMPRLSPVGMVT----VIDADKGENAHIHLSVE 660 HSP 3 Score: 83.1889 bits (204), Expect = 1.989e-15 Identity = 97/365 (26.58%), Postives = 156/365 (42.74%), Query Frame = 3
Query: 1332 YEIKSKIDFD--RETKTLH-----FVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI------DKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSL 2378
Y ++ ID + RE + L F+ S T+ ++ + + ++ I DINDN P F+SP + EN I + P ATD+D G NG Y + V + ++ F + D+ + + LD E+ + I +D G P R+SS L +++ DTNDN P+ + Y EL EN P+G V +V D D +N + + S ++ +D +G I + +DRE + F+++A D G + T VT+ I D NDN P++ ++ V NI + V P V D+DEG N+ V + + F L
Sbjct: 118 YTTETSIDRESLRECQNLEPGEKCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPEN--TNIGMLFPIPA-ATDRDSGVNGVSSYELI-VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQ---------ASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAK-----DKGAN-----PKTARTQVTITIRDTNDNKPVIEIRGFGLV---------THQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQL 450 HSP 4 Score: 67.781 bits (164), Expect = 9.591e-11 Identity = 66/230 (28.70%), Postives = 94/230 (40.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYS--FNLVAK--DFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + DAD EN ++ + E + N ++ DRE F L AVDGG PPR + + VLDEND P S + Y+ ++ G + +R ED D+G N ++ + AS N F+L Q H + K I K+ LV K D G+P R TALV ++
Sbjct: 614 NDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADK-------------GENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTH-PGTPVNWVRAEDMDTGINAELDYSIASG------NPFELFQISHNNGEVTLEK---AIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 227.639 bits (579), Expect = 1.036e-60 Identity = 182/651 (27.96%), Postives = 307/651 (47.16%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I +P A D D GV SYE+ E D++ + ED D KQP LIV +DRE D + T+ DGG P R + + +LD ND P+F ++ YE ++ E+ G +L ++ D D G N +I +F +++ ++ L ++ + ++ +D E + F++VAKD G P+++ V + + + ND+ P I F ++ Q I+E + + LV+V+D D ++ + F L + +++K Y +++ D E+ + + IV D+ G L TN L+V + D+NDNAPVFS + EN +N++V + ATD D G N + Y I + D + FSI+ ++G ++ LD E+ +H + A D G+P + +++ V D NDN P+ L+ Y+F + EN P + VG V V D D N + + +P F I N +G I + + DRE S F + A + G D R + + VT+N+LD+NDN+P++++ K + P+ +P V + D+D G N+++ ++ + + F L
Sbjct: 170 NDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAED-QDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQ--GPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGL-VTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGS-DSKKKYFLQTTTALDYESVKEYTIEIVAVDS-GNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVM----EVSATDADSGPNSQLHYSI--LPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHL-------------SVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVD------GGDPPR----SSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQT-----------HPGTPVNW-VRAEDMDTGINAELDYSIASGNPFEL 772 HSP 2 Score: 137.502 bits (345), Expect = 3.509e-32 Identity = 154/561 (27.45%), Postives = 235/561 (41.89%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD-----PIL---ATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++++D ND P F+ + + I E+ G+ D+DSG NG S + Q+ F L Q L ++ LD E + Y + +D G P R+S+AL+ + + + ND+ P K + E + + VK D D + EI+ SF+ + +L +R T I + DRE TL F S+V D +G N ++ + I+D NDN PV R +G+V + I++D P+ +D DEG N V ++ V D K YF ++T LDYE +K +IEI A D G P SS+ L V V D NDN P S EN I V +V+ TD D+ ++LP P+ A IF+I+ +SG+I VLDRE F ++A +D G + T SV + +LD+NDN P ML +F + P VT +D D+GEN+ + ++++
Sbjct: 164 IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELI--VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPK---------FEKMAYEAELPENSPMGHSVLQVKANDSDQ---GVNAEIDY---SFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKF-SVVAKD-KGANPKTARTQVTITIRDTNDNKPVIEI-RGFGLVTHQ--GGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYF--------LQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSG----PNSQLHYSILPDPS------ARGIFSINPDSGQIRVNTVLDREQREHYDFHVVA-----VDKG---IPSLKGTA--SVVITVLDRNDNDPKFMLNG----------YNFSVMENMPRLSPVGMVT----VIDADKGENAHIHLSVE 660 HSP 3 Score: 82.4185 bits (202), Expect = 3.089e-15 Identity = 97/365 (26.58%), Postives = 156/365 (42.74%), Query Frame = 3
Query: 1332 YEIKSKIDFD--RETKTLH-----FVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI------DKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSL 2378
Y ++ ID + RE + L F+ S T+ ++ + + ++ I DINDN P F+SP + EN I + P ATD+D G NG Y + V + ++ F + D+ + + LD E+ + I +D G P R+SS L +++ DTNDN P+ + Y EL EN P+G V +V D D +N + + S ++ +D +G I + +DRE + F+++A D G + T VT+ I D NDN P++ ++ V NI + V P V D+DEG N+ V + + F L
Sbjct: 118 YTTETSIDRESLRECQNLEPGEKCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPEN--TNIGMLFPIPA-ATDRDSGVNGVSSYELI-VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQ---------ASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAK-----DKGAN-----PKTARTQVTITIRDTNDNKPVIEIRGFGLV---------THQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQL 450 HSP 4 Score: 67.781 bits (164), Expect = 9.362e-11 Identity = 66/230 (28.70%), Postives = 94/230 (40.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYS--FNLVAK--DFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + DAD EN ++ + E + N ++ DRE F L AVDGG PPR + + VLDEND P S + Y+ ++ G + +R ED D+G N ++ + AS N F+L Q H + K I K+ LV K D G+P R TALV ++
Sbjct: 614 NDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADK-------------GENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTH-PGTPVNWVRAEDMDTGINAELDYSIASG------NPFELFQISHNNGEVTLEK---AIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 228.409 bits (581), Expect = 1.149e-60 Identity = 182/651 (27.96%), Postives = 309/651 (47.47%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I +P A D D GV SYE+ E D++ + ED D KQP LIV +DRE D + T+ DGG P R + + +LD ND P+F ++ YE ++ E+ G +L ++ D D G N +I +F +++ ++ L ++ + ++ +D E + F++VAKD G P+++ V + + + ND+ P I F ++ Q I+E + + LV+V+D D ++ + F L + ++ +++K Y +++ D E+ + + IV D+ G L TN L+V + D+NDNAPVFS + EN +N++V + ATD D G N + Y I + D + FSI+ ++G ++ LD E+ +H + A D G+P + +++ V D NDN P+ L+ Y+F + EN P + VG V V D D N + + +P F I N +G I + + DRE S F + A + G D R + + VT+N+LD+NDN+P++++ K + P+ +P V + D+D G N+++ ++ + + F L
Sbjct: 170 NDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAED-QDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQ--GPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGL-VTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQV-SDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDS-GNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVM----EVSATDADSGPNSQLHYSI--LPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHL-------------SVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVD------GGDPPR----SSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQT-----------HPGTPVNW-VRAEDMDTGINAELDYSIASGNPFEL 772 HSP 2 Score: 138.658 bits (348), Expect = 1.605e-32 Identity = 154/561 (27.45%), Postives = 235/561 (41.89%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD-----PIL---ATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++++D ND P F+ + + I E+ G+ D+DSG NG S + Q+ F L Q L ++ LD E + Y + +D G P R+S+AL+ + + + ND+ P K + E + + VK D D + EI+ SF+ + +L +R T I + DRE TL F S+V D +G N ++ + I+D NDN PV R +G+V + I++D P+ +D DEG N V ++ V D K YF ++T LDYE +K +IEI A D G P SS+ L V V D NDN P S EN I V +V+ TD D+ ++LP P+ A IF+I+ +SG+I VLDRE F ++A +D G + T SV + +LD+NDN P ML +F + P VT +D D+GEN+ + ++++
Sbjct: 164 IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELI--VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPK---------FEKMAYEAELPENSPMGHSVLQVKANDSDQ---GVNAEIDY---SFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKF-SVVAKD-KGANPKTARTQVTITIRDTNDNKPVIEI-RGFGLVTHQ--GGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYF--------LQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSG----PNSQLHYSILPDPS------ARGIFSINPDSGQIRVNTVLDREQREHYDFHVVA-----VDKG---IPSLKGTA--SVVITVLDRNDNDPKFMLNG----------YNFSVMENMPRLSPVGMVT----VIDADKGENAHIHLSVE 660 HSP 3 Score: 83.1889 bits (204), Expect = 1.810e-15 Identity = 97/365 (26.58%), Postives = 156/365 (42.74%), Query Frame = 3
Query: 1332 YEIKSKIDFD--RETKTLH-----FVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI------DKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSL 2378
Y ++ ID + RE + L F+ S T+ ++ + + ++ I DINDN P F+SP + EN I + P ATD+D G NG Y + V + ++ F + D+ + + LD E+ + I +D G P R+SS L +++ DTNDN P+ + Y EL EN P+G V +V D D +N + + S ++ +D +G I + +DRE + F+++A D G + T VT+ I D NDN P++ ++ V NI + V P V D+DEG N+ V + + F L
Sbjct: 118 YTTETSIDRESLRECQNLEPGEKCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPEN--TNIGMLFPIPA-ATDRDSGVNGVSSYELI-VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQ---------ASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAK-----DKGAN-----PKTARTQVTITIRDTNDNKPVIEIRGFGLV---------THQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQL 450 HSP 4 Score: 68.1662 bits (165), Expect = 7.488e-11 Identity = 66/230 (28.70%), Postives = 94/230 (40.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYS--FNLVAK--DFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + DAD EN ++ + E + N ++ DRE F L AVDGG PPR + + VLDEND P S + Y+ ++ G + +R ED D+G N ++ + AS N F+L Q H + K I K+ LV K D G+P R TALV ++
Sbjct: 614 NDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADK-------------GENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTH-PGTPVNWVRAEDMDTGINAELDYSIASG------NPFELFQISHNNGEVTLEK---AIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 227.639 bits (579), Expect = 1.262e-60 Identity = 182/651 (27.96%), Postives = 309/651 (47.47%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I +P A D D GV SYE+ E D++ + ED D KQP LIV +DRE D + T+ DGG P R + + +LD ND P+F ++ YE ++ E+ G +L ++ D D G N +I +F +++ ++ L ++ + ++ +D E + F++VAKD G P+++ V + + + ND+ P I F ++ Q I+E + + LV+V+D D ++ + F L + ++ +++K Y +++ D E+ + + IV D+ G L TN L+V + D+NDNAPVFS + EN +N++V + ATD D G N + Y I + D + FSI+ ++G ++ LD E+ +H + A D G+P + +++ V D NDN P+ L+ Y+F + EN P + VG V V D D N + + +P F I N +G I + + DRE S F + A + G D R + + VT+N+LD+NDN+P++++ K + P+ +P V + D+D G N+++ ++ + + F L
Sbjct: 170 NDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAED-QDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDT-VRRLLHLDRSTGLITVQ--GPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGL-VTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQV-SDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDS-GNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVM----EVSATDADSGPNSQLHYSI--LPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHL-------------SVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVD------GGDPPR----SSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQT-----------HPGTPVNW-VRAEDMDTGINAELDYSIASGNPFEL 772 HSP 2 Score: 137.502 bits (345), Expect = 3.096e-32 Identity = 154/561 (27.45%), Postives = 235/561 (41.89%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD-----PIL---ATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++++D ND P F+ + + I E+ G+ D+DSG NG S + Q+ F L Q L ++ LD E + Y + +D G P R+S+AL+ + + + ND+ P K + E + + VK D D + EI+ SF+ + +L +R T I + DRE TL F S+V D +G N ++ + I+D NDN PV R +G+V + I++D P+ +D DEG N V ++ V D K YF ++T LDYE +K +IEI A D G P SS+ L V V D NDN P S EN I V +V+ TD D+ ++LP P+ A IF+I+ +SG+I VLDRE F ++A +D G + T SV + +LD+NDN P ML +F + P VT +D D+GEN+ + ++++
Sbjct: 164 IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELI--VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPK---------FEKMAYEAELPENSPMGHSVLQVKANDSDQ---GVNAEIDY---SFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKF-SVVAKD-KGANPKTARTQVTITIRDTNDNKPVIEI-RGFGLVTHQ--GGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYF--------LQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSG----PNSQLHYSILPDPS------ARGIFSINPDSGQIRVNTVLDREQREHYDFHVVA-----VDKG---IPSLKGTA--SVVITVLDRNDNDPKFMLNG----------YNFSVMENMPRLSPVGMVT----VIDADKGENAHIHLSVE 660 HSP 3 Score: 82.8037 bits (203), Expect = 2.649e-15 Identity = 97/367 (26.43%), Postives = 156/367 (42.51%), Query Frame = 3
Query: 1332 YEIKSKIDFD--RETKTLH-----FVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI------DKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN--PNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSL 2378
Y ++ ID + RE + L F+ S T+ ++ + + ++ I DINDN P F+SP + EN I + P ATD+D G NG Y + V + ++ F + D+ + + LD E+ + I +D G P R+SS L +++ DTNDN P+ + Y EL EN P+G V +V D D +N + + S ++ +D +G I + +DRE + F+++A + NP T VT+ I D NDN P++ ++ V NI + V P V D+DEG N+ V + + F L
Sbjct: 118 YTTETSIDRESLRECQNLEPGEKCFLEFEVSMTDLMSPVPRLLDGQIEIMDINDNTPNFNSPVITLSIPEN--TNIGMLFPIPA-ATDRDSGVNGVSSYELI-VGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQ---------ASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANP------------KTARTQVTITIRDTNDNKPVIEIRGFGLV---------THQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQL 450 HSP 4 Score: 67.781 bits (164), Expect = 1.079e-10 Identity = 66/230 (28.70%), Postives = 94/230 (40.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYS--FNLVAK--DFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + DAD EN ++ + E + N ++ DRE F L AVDGG PPR + + VLDEND P S + Y+ ++ G + +R ED D+G N ++ + AS N F+L Q H + K I K+ LV K D G+P R TALV ++
Sbjct: 614 NDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADK-------------GENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTH-PGTPVNWVRAEDMDTGINAELDYSIASG------NPFELFQISHNNGEVTLEK---AIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 229.18 bits (583), Expect = 3.139e-61 Identity = 181/651 (27.80%), Postives = 304/651 (46.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I S +P+A D D P GV SYE++ E +++ + ED + KQP LIV +DRE D + T+ DGG PPR + + VLD ND P+F + YE ++ E+ G ++ ++ D D G N +I F + + ++ +L + + ++ +D E ++ F+++AKD G P+S+ A V V V ++ND+ P I ++ Q I+E ++ + LV+V+D D+ + ++TC + A +T + +++K Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF+ S + N+ E+V + A+D D G N + Y + + F+I G ++ LD E+ +++ A D G P + ++VNV D NDN P+ LS Y+F + EN P + VG V V D D N + L Q + F I N +G I + + DRE S F + A +D G + + VT+N+LD+NDN+P + + + P+ +T + D+D G N+++ ++ + + L
Sbjct: 1 NDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAED-QEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAP-EVVRRLLRLDRNTGLITVQ--GPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGL-VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGS--DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVA----EVTASDADSGSNAELVYSL-EPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQ------------LSVEQ-DNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKA-----VDGGVPPRSAY-----VGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGETVSQ------------VTAEDIDSGINAELTYSIAGGNPYGL 603 HSP 2 Score: 70.4774 bits (171), Expect = 1.134e-11 Identity = 59/223 (26.46%), Postives = 93/223 (41.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEP---QFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + D D +E+ N +F + N ++ DRE F L AVDGG PPR + + VLDEND P S + + ++ + G + + ED DSG N +++ + A + FQ+ H A+ L +++ + + D G+PPR TALV ++V
Sbjct: 445 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDF----------VIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRL-GETVSQVTAEDIDSGINAELTYSIAGGNPYGL---FQIGS--HSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 651
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 227.639 bits (579), Expect = 6.780e-61 Identity = 181/651 (27.80%), Postives = 304/651 (46.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I S +P+A D D P GV SYE++ E +++ + ED + KQP LIV +DRE D + T+ DGG PPR + + VLD ND P+F + YE ++ E+ G ++ ++ D D G N +I F + + ++ +L + + ++ +D E ++ F+++AKD G P+S+ A V V V ++ND+ P I ++ Q I+E ++ + LV+V+D D+ + ++TC + A +T + +++K Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF+ S + N+ E+V + A+D D G N + Y + + F+I G ++ LD E+ +++ A D G P + ++VNV D NDN P+ LS Y+F + EN P + VG V V D D N + L Q + F I N +G I + + DRE S F + A +D G + + VT+N+LD+NDN+P + + + P+ +T + D+D G N+++ ++ + + L
Sbjct: 140 NDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAED-QEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAP-EVVRRLLRLDRNTGLITVQ--GPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGL-VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGS--DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVA----EVTASDADSGSNAELVYSLEP-EPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQ------------LSVEQ-DNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKA-----VDGGVPPRSAY-----VGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGETVSQ------------VTAEDIDSGINAELTYSIAGGNPYGL 742 HSP 2 Score: 88.1965 bits (217), Expect = 3.950e-17 Identity = 89/319 (27.90%), Postives = 141/319 (44.20%), Query Frame = 3
Query: 1446 EVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI-------DKNTGVVKTILG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
++ ++DINDN P F+SP + EN I ++ P LATD+D G NG Y + + + F + +K ++ ++G LD E+ + I +D G P R+SS L V V DTNDN P+ + Y EL EN PIG V +V D D N + + + ++ +D +G I + +DRE S + F+++A D G + V V + D NDN+P + ++ + V + S E++ E V + D DEGEN+ V + + F L
Sbjct: 133 QIEVQDINDNTPNFASPVITLAIPEN--TNIGSLFPIP-LATDRDAGPNGVASYEL-QAGPEAQELFGLQVAEDQEEKQPQLI--VMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQ---------APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK-----DRGA-----TPKSARAQVVVTVKDMNDNAPTIEIRG---IGLVTHQDGMANIS--EDVAEETAVALVQVS-DRDEGENAAVTCVVAGDVPFQL 420 HSP 3 Score: 70.0922 bits (170), Expect = 1.349e-11 Identity = 59/223 (26.46%), Postives = 93/223 (41.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEP---QFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + D D +E+ N +F + N ++ DRE F L AVDGG PPR + + VLDEND P S + + ++ + G + + ED DSG N +++ + A + FQ+ H A+ L +++ + + D G+PPR TALV ++V
Sbjct: 584 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDF----------VIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRL-GETVSQVTAEDIDSGINAELTYSIAGGNPYGL---FQIGS--HSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 790
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 227.639 bits (579), Expect = 6.780e-61 Identity = 181/651 (27.80%), Postives = 304/651 (46.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ I S +P+A D D P GV SYE++ E +++ + ED + KQP LIV +DRE D + T+ DGG PPR + + VLD ND P+F + YE ++ E+ G ++ ++ D D G N +I F + + ++ +L + + ++ +D E ++ F+++AKD G P+S+ A V V V ++ND+ P I ++ Q I+E ++ + LV+V+D D+ + ++TC + A +T + +++K Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF+ S + N+ E+V + A+D D G N + Y + + F+I G ++ LD E+ +++ A D G P + ++VNV D NDN P+ LS Y+F + EN P + VG V V D D N + L Q + F I N +G I + + DRE S F + A +D G + + VT+N+LD+NDN+P + + + P+ +T + D+D G N+++ ++ + + L
Sbjct: 140 NDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAED-QEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAP-EVVRRLLRLDRNTGLITVQ--GPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGL-VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGS--DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVA----EVTASDADSGSNAELVYSLEP-EPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQ------------LSVEQ-DNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKA-----VDGGVPPRSAY-----VGVTINVLDENDNAPFITAPSNTSHRLLTPQTRLGETVSQ------------VTAEDIDSGINAELTYSIAGGNPYGL 742 HSP 2 Score: 88.1965 bits (217), Expect = 3.950e-17 Identity = 89/319 (27.90%), Postives = 141/319 (44.20%), Query Frame = 3
Query: 1446 EVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI-------DKNTGVVKTILG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
++ ++DINDN P F+SP + EN I ++ P LATD+D G NG Y + + + F + +K ++ ++G LD E+ + I +D G P R+SS L V V DTNDN P+ + Y EL EN PIG V +V D D N + + + ++ +D +G I + +DRE S + F+++A D G + V V + D NDN+P + ++ + V + S E++ E V + D DEGEN+ V + + F L
Sbjct: 133 QIEVQDINDNTPNFASPVITLAIPEN--TNIGSLFPIP-LATDRDAGPNGVASYEL-QAGPEAQELFGLQVAEDQEEKQPQLI--VMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQ---------APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK-----DRGA-----TPKSARAQVVVTVKDMNDNAPTIEIRG---IGLVTHQDGMANIS--EDVAEETAVALVQVS-DRDEGENAAVTCVVAGDVPFQL 420 HSP 3 Score: 70.0922 bits (170), Expect = 1.349e-11 Identity = 59/223 (26.46%), Postives = 93/223 (41.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEP---QFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + D D +E+ N +F + N ++ DRE F L AVDGG PPR + + VLDEND P S + + ++ + G + + ED DSG N +++ + A + FQ+ H A+ L +++ + + D G+PPR TALV ++V
Sbjct: 584 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDF----------VIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRLLTPQTRL-GETVSQVTAEDIDSGINAELTYSIAGGNPYGL---FQIGS--HSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 790
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh9 (protocadherin 9 [Source:MGI Symbol;Acc:MGI:1306801]) HSP 1 Score: 207.223 bits (526), Expect = 5.166e-54 Identity = 200/702 (28.49%), Postives = 317/702 (45.16%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL-MTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM---KNNDYFSLTPDYGMLCAMEKLPP--IGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I EN+ INSR +P A D D GV+ YE+ N F L + E K P LIV+ +DRE D + DGG P + + + V D ND P F + E+ I E+ G ++ L D D G+N +I F + + F L+ T + ++ LD E + ++A D P +T V + VT+VND+PPNI PI+ +Y++E + I L+ V+D D + + C IE + F+L A V +N+ E S +D++ TK F IV SD+ G L QT + V ++D NDN P+F+ P V EN + I ATD+D G+N + Y + ++F +D+ TGV+ + E+ + ++A+D G P S +IV V D NDN P+ + + F + EN P + VG + VTD+D N + + + ++ F +D SG I + V DRE S F + A+ D G Q + VT+N++D NDNSP+++ + P +S I S ++ VD+D G N++++ T+ N F + P G + EK P +G ++ V+ D + + L+ +++ +
Sbjct: 136 NDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELL----NGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQ--RSLDREETAIHKVTVLASDGSSTPARAT--VTINVTDVNDNPPNIDLRYIISPIN---GTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIE-REVPFHLKA-----VYDNQYLLETSSLLDYEG-TKEFSF-KIVASDS-GKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT---ISATDEDSGKNADIVYQLG----PNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILND-------------NENFVLDPYSGVIKSNVSFDREQQSSYTFDVKAT-----DGG-----QPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVP-LSAIPGSVVAEVF----------AVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVND 776 HSP 2 Score: 103.219 bits (256), Expect = 1.135e-21 Identity = 150/573 (26.18%), Postives = 237/573 (41.36%), Query Frame = 3
Query: 738 KTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKIS---INFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQ-YARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-----NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTIN-KDP-------ILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN-NDYFSLTPDYGML 2399
K KII+K D ND P F + I I E+ + D D+G NG +N S DI T + + L + LD E + Y + +D G P +SSTA+++V V++VND N+P+ K+ ++I E + + TD D I ++ E Y+ + + N T I + DRE +H V+++ SD + + + + D+NDN P RY I+ +N V ++ KDP I +DKD NG V +I V +K + N +++T LDYE K S +I A D G P + + + V ++D NDN P + + EN G Y+ ++ TD+D+ N + LG P F +D ++G + V +RE + F + A D G + + +V V +LD+NDNSP K + F +EN+ P+ D D GEN V +++ N N+ F L P G++
Sbjct: 127 KIKIIVK--DTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQ---LIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVND----------NRPVFKEGQVEVHIPENAPVGTSVIQLHATDAD---------IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDG---SSTPARATVTINVTDVNDNPPNIDL-RY--IISP--INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ----------LG---PNASFFDLDRKTGVLTASRVFNREEQERFIFTVTAR-----DNGTPPLQS-----QAAVIVTVLDENDNSP----------KFTHNHFQFF---VSENL-PKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVI 627
BLAST of Protocadherin-1 vs. Ensembl Mouse
Match: Pcdh9 (protocadherin 9 [Source:MGI Symbol;Acc:MGI:1306801]) HSP 1 Score: 207.223 bits (526), Expect = 5.166e-54 Identity = 200/702 (28.49%), Postives = 317/702 (45.16%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL-MTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM---KNNDYFSLTPDYGMLCAMEKLPP--IGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I EN+ INSR +P A D D GV+ YE+ N F L + E K P LIV+ +DRE D + DGG P + + + V D ND P F + E+ I E+ G ++ L D D G+N +I F + + F L+ T + ++ LD E + ++A D P +T V + VT+VND+PPNI PI+ +Y++E + I L+ V+D D + + C IE + F+L A V +N+ E S +D++ TK F IV SD+ G L QT + V ++D NDN P+F+ P V EN + I ATD+D G+N + Y + ++F +D+ TGV+ + E+ + ++A+D G P S +IV V D NDN P+ + + F + EN P + VG + VTD+D N + + + ++ F +D SG I + V DRE S F + A+ D G Q + VT+N++D NDNSP+++ + P +S I S ++ VD+D G N++++ T+ N F + P G + EK P +G ++ V+ D + + L+ +++ +
Sbjct: 136 NDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELL----NGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQ--RSLDREETAIHKVTVLASDGSSTPARAT--VTINVTDVNDNPPNIDLRYIISPIN---GTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIE-REVPFHLKA-----VYDNQYLLETSSLLDYEG-TKEFSF-KIVASDS-GKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT---ISATDEDSGKNADIVYQLG----PNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILND-------------NENFVLDPYSGVIKSNVSFDREQQSSYTFDVKAT-----DGG-----QPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVP-LSAIPGSVVAEVF----------AVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVND 776 HSP 2 Score: 103.219 bits (256), Expect = 1.135e-21 Identity = 150/573 (26.18%), Postives = 237/573 (41.36%), Query Frame = 3
Query: 738 KTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKIS---INFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQ-YARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-----NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTIN-KDP-------ILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN-NDYFSLTPDYGML 2399
K KII+K D ND P F + I I E+ + D D+G NG +N S DI T + + L + LD E + Y + +D G P +SSTA+++V V++VND N+P+ K+ ++I E + + TD D I ++ E Y+ + + N T I + DRE +H V+++ SD + + + + D+NDN P RY I+ +N V ++ KDP I +DKD NG V +I V +K + N +++T LDYE K S +I A D G P + + + V ++D NDN P + + EN G Y+ ++ TD+D+ N + LG P F +D ++G + V +RE + F + A D G + + +V V +LD+NDNSP K + F +EN+ P+ D D GEN V +++ N N+ F L P G++
Sbjct: 127 KIKIIVK--DTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQ---LIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVND----------NRPVFKEGQVEVHIPENAPVGTSVIQLHATDAD---------IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDG---SSTPARATVTINVTDVNDNPPNIDL-RY--IISP--INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ----------LG---PNASFFDLDRKTGVLTASRVFNREEQERFIFTVTAR-----DNGTPPLQS-----QAAVIVTVLDENDNSP----------KFTHNHFQFF---VSENL-PKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVI 627
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q08174|PCDH1_HUMAN (Protocadherin-1 OS=Homo sapiens OX=9606 GN=PCDH1 PE=1 SV=2) HSP 1 Score: 231.491 bits (589), Expect = 3.589e-61 Identity = 179/610 (29.34%), Postives = 292/610 (47.87%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKT 2255
NDN+P F I EN+ I S +P+A D D P GV SYE++ E +++ + ED + KQP LIV +DRE D + T+ DGG PPR + + VLD ND P+F + YE ++ E+ G ++ ++ D D G N +I F + + ++ +L + + ++ +D E ++ F+++AKD G P+S+ A V V V ++ND+ P I ++ Q I+E ++ + LV+V+D D+ + ++TC + A +T + +++K Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF+ S + N+ E++ I A+D D G N + Y + K F+I TG ++ LD E+ + +++ A D G P + ++VNV D NDN P+ LS Y+F + EN P + VG V V D D N + L Q + F I N +G I + + DRE S F + A +D G + + VT+N+LD+NDN+P + K + P+ +T
Sbjct: 162 NDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAED-QEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAP-EVVRRLLRLDRNTGLITVQ--GPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGL-VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGS--DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIA----EITASDADSGSNAELVYSLEP-EPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ------------LSVEQ-DNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKA-----VDGGVPPRSAY-----VGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGET 735 HSP 2 Score: 141.739 bits (356), Expect = 7.589e-33 Identity = 160/567 (28.22%), Postives = 243/567 (42.86%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS----QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRE-TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDP--------ILATDKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK--NNDY 2369
++V D ND P F+ + + I E+ G D+D+G NG S + + Q F L Q L ++ LD E + Y + +D G PPR+S+AL+ V V + ND+ P +F +P + ++E + + VK D D A++ EIE + F+ +L +R T I + DRE TL F S++ D G N ++ V +KD+NDNAP R G+V + + I++D + +D+DEGEN V ++ V D K YF ++T LDYEK+K +IEI A D G P SS+ L V V D NDN P S EN G + ++ +D D+ N + + L P P A +FTI E+G+I K LDRE ++A+ D G + +V VN+LD NDN P ML +F + P VT +D D+GEN++V+++++ N D+
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP--EAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAP-----KFERPSYE----AELSENSPIGHSVIQVKANDSDQGANA---EIEYT---FHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRF-SVLAKD-RGTNPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQ--DGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYF--------LQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYS----LEPEPA------AKGLFTISPETGEIQVKTSLDREQRESYELKVVAA-----DRGSPSLQG-----TATVLVNVLDCNDNDPKFMLSG----------YNFSVMENMPALSPVGMVTV----IDGDKGENAQVQLSVEQDNGDF 658 HSP 3 Score: 88.9669 bits (219), Expect = 1.691e-16 Identity = 88/319 (27.59%), Postives = 142/319 (44.51%), Query Frame = 3
Query: 1446 EVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI-------DKNTGVVKTILG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
++ ++DINDN P F+SP + EN I ++ P LA+D+D G NG Y + + + F + +K ++ ++G LD E+ + I +D G P R+SS L V V DTNDN P+ + Y EL EN PIG V +V D D N + + + ++ +D +G I + +DRE S + F+++A D G + + V V + D NDN+P + ++ + V + S E++ E V + D DEGEN+ V + + F L
Sbjct: 155 QIEVQDINDNTPNFASPVITLAIPEN--TNIGSLFPIP-LASDRDAGPNGVASYEL-QAGPEAQELFGLQVAEDQEEKQPQLI--VMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ---------APEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK-----DRGTN-----PKSARAQVVVTVKDMNDNAPTIEIRG---IGLVTHQDGMANIS--EDVAEETAVALVQV-SDRDEGENAAVTCVVAGDVPFQL 442 HSP 4 Score: 69.3218 bits (168), Expect = 1.624e-10 Identity = 59/223 (26.46%), Postives = 93/223 (41.70%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF---SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y ++EN S + + D D +E+ N +F + N ++ DRE F L AVDGG PPR + + VLDEND P S +++ ++ + G + + ED DSG N ++ + A + FQ+ H A+ L +++ + + D G+PPR TALV ++V
Sbjct: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDF----------VIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRL-GETVSQVAAEDFDSGVNAELIYSIAGGNPYGL---FQIGS--HSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q9BZA8|PC11Y_HUMAN (Protocadherin-11 Y-linked OS=Homo sapiens OX=9606 GN=PCDH11Y PE=1 SV=1) HSP 1 Score: 214.927 bits (546), Expect = 1.433e-55 Identity = 209/701 (29.81%), Postives = 316/701 (45.08%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEK--LPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I ENS INS+ +LP A D D GV++YE+ K F + + E +K P LIV+ ++DRE D + DGG P R + + V D ND P F + E+ I E+ G + L D D G N KI +F++ + + F L+ T + +K LD E + ++A D G P + A+V V VT+VND+ P+I P++ + ++E + I L+ VTD D + +TC + + F L + +N L Y D E+ + + ++ +D G L Q+ L + +KD NDNAPVF+ + EN I + + ATD D G N + Y + D FS+D+ TG++ + LD EK I AKD GVP +S+V + V++ D NDN P + Y F + EN P VG + VTD D N+ TL D FTID+++G I + DRE F + A +D R R + VT+N++D NDN P+ + V N + STN V F I VD D G N++VR V D F++ + G + MEK + +G ++ ++ A D +S ++N+ + E
Sbjct: 165 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK--EPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT---VVLSENIPLNTKIALITVTDKDADHNGRVTCFTD-HEIPFRLRPVFSNQFLLENAAY-------LDYESTKEYAIKLLAADA-GKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK---VSATDADSGPNAEINYLLG---PDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV------------TLSILDENDD-FTIDSQTGVIRPNISFDREKQESYTFYVKA---------EDGGRVSRSS-SAKVTINVVDVNDNKPVFI------VPPYNYSYELVLPSTN-----PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNE 806 HSP 2 Score: 73.9442 bits (180), Expect = 7.794e-12 Identity = 79/267 (29.59%), Postives = 118/267 (44.19%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
K+ +I+DINDNAP+F + + EN +N T+ A D D G NG Y + +N F +D V++T G LD E+ +++ +D G P RSS+ L V+V DTNDN P + + EN P+GT V +++ TD D N K + S A ++F ++ +G I K LDRE + ++AS D G R V VN+ D NDN P + ++
Sbjct: 156 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA----AVDPDVGINGVQNYELIK----SQNIFGLD----VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLV--------SNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLAS-----DGGLMPARAM-------VLVNVTDVNDNVPSIDIR 390
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q6WXV7|PC11X_PONPY (Protocadherin-11 X-linked OS=Pongo pygmaeus OX=9600 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 214.927 bits (546), Expect = 1.538e-55 Identity = 210/701 (29.96%), Postives = 315/701 (44.94%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEK--LPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I ENS INS+ +LP A D D GV++YE+ K F + + E +K P LIV+ ++DRE D + DGG P R + + V D ND P F + E+ I E+ G + L D D G N KI +F++ + + F L+ T + +K LD E + ++A D G P + A+V V VT+VND+ P+I PI+ + ++E + I L+ VTD D + +TC + F L + +N L Y D E+ + + ++ +D G L Q+ L + +KD NDNAPVF+ + EN I + ATD D G N + Y + D FS+D+ TG++ + LD EK I AKD GVP +S+V + V++ D NDN P + Y+F + EN P VG + VTD D N+ TL D FTID+++G I + DRE F + A +D R R + VT+N++D NDN P+ + V N + STN V F I VD D G N++VR V D F++ + G + MEK + +G ++ ++ A D +S ++N+ + E
Sbjct: 133 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK--EPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPINDT---VVLSENIPLNTKIALITVTDKDADHNGRVTC-FTDHEIPFRLRPVFSNQFLLETAAY-------LDYESTKEYAIKLLAADA-GKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK---VSATDADSGPNAEINYLLG---PDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV------------TLSILDENDD-FTIDSQTGVIRPNISFDREKQESYTFYVKA---------EDGGRVSRSS-SAKVTINVVDVNDNKPVFI------VPPSNYSYELVLPSTN-----PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNE 774 HSP 2 Score: 74.3294 bits (181), Expect = 6.002e-12 Identity = 79/267 (29.59%), Postives = 118/267 (44.19%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
K+ +I+DINDNAP+F + + EN +N T+ A D D G NG Y + +N F +D V++T G LD E+ +++ +D G P RSS+ L V+V DTNDN P + + EN P+GT V +++ TD D N K + S A ++F ++ +G I K LDRE + ++AS D G R V VN+ D NDN P + ++
Sbjct: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA----AVDPDVGINGVQNYELIK----SQNIFGLD----VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLV--------SNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLAS-----DGGLMPARAM-------VLVNVTDVNDNVPSIDIR 358
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 214.927 bits (546), Expect = 1.786e-55 Identity = 209/701 (29.81%), Postives = 315/701 (44.94%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEK--LPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I ENS INS+ +LP A D D GV++YE+ K F + + E +K P LIV+ ++DRE D + DGG P R + + V D ND P F + E+ I E+ G + L D D G N KI +F++ + + F L+ T + +K LD E + ++A D G P + A+V V VT+VND+ P+I P++ + ++E + I L+ VTD D + +TC + F L + +N L Y D E+ + + ++ +D G L Q+ L + +KD NDNAPVF+ + EN I + ATD D G N + Y + D FS+D+ TG++ + LD EK I AKD GVP +S+V + V++ D NDN P + Y+F + EN P VG + VTD D N+ TL D FTID+++G I + DRE F + A +D R R + VT+N++D NDN P+ + V N + STN V F I VD D G N++VR V D F++ + G + MEK + +G ++ ++ A D +S ++N+ + E
Sbjct: 133 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNMFGLD---VIETPEGDKMPQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK--EPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT---VVLSENIPLNTKIALITVTDKDADHNGRVTC-FTDHEIPFRLRPVFSNQFLLETAAY-------LDYESTKEYAIKLLAADA-GKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK---VSATDADSGPNAEINYLLG---PDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV------------TLSILDENDD-FTIDSQTGVIRPNISFDREKQESYTFYVKA---------EDGGRVSRSS-SAKVTINVVDVNDNKPVFI------VPPSNYSYELVLPSTN-----PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNE 774 HSP 2 Score: 75.8702 bits (185), Expect = 2.045e-12 Identity = 80/267 (29.96%), Postives = 118/267 (44.19%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
K+ +I+DINDNAP+F + + EN +N T+ A D D G NG Y + +N F +D V++T G LD EK +++ +D G P RSS+ L V+V DTNDN P + + EN P+GT V +++ TD D N K + S A ++F ++ +G I K LDRE + ++AS D G R V VN+ D NDN P + ++
Sbjct: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA----AVDPDVGINGVQNYELIK----SQNMFGLD----VIETPEGDKMPQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLV--------SNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLAS-----DGGLMPARAM-------VLVNVTDVNDNVPSIDIR 358
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Match: sp|Q6WYY1|PC11X_PANPA (Protocadherin-11 X-linked OS=Pan paniscus OX=9597 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 213.772 bits (543), Expect = 3.974e-55 Identity = 208/701 (29.67%), Postives = 316/701 (45.08%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEK--LPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP I ENS INS+ +LP A D D GV++YE+ K F + + E +K P LIV+ ++DRE D + DGG P R + + V D ND P F + E+ I E+ G + L D D G N KI +F++ + + F L+ T + +K LD E + ++A D G P + A+V V VT+VND+ P+I P++ + ++E + I L+ VTD D + +TC + + F L + +N L Y D E+ + + ++ +D G L Q+ L + +KD NDNAPVF+ + EN I + ATD D G N + Y + D FS+D+ TG++ + LD EK I AKD GVP +S+V + V++ D NDN P + Y+F + EN P VG + VTD D N+ TL D FTID+++G I + DRE F + A +D R R + VT+N++D NDN P+ + V N + STN V F + VD D G N++VR V D F++ + G + MEK + +G ++ ++ A D +S ++N+ + E
Sbjct: 133 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGTNGVQNYELIKSQNIFGLD---VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK--EPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT---VVLSENIPLNTKIALITVTDKDADHNGRVTCFTD-HEIPFRLRPVFSNQFLLETAAY-------LDYESTKEYAIKLLAADA-GKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK---VSATDADSGPNAEINYLLG---PDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV------------TLSILDENDD-FTIDSQTGVIRPNISFDREKQESYTFYVKA---------EDGGRVSRSS-SAKVTINVVDVNDNKPVFI------VPPSNYSYELVLPSTN-----PGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNE 774 HSP 2 Score: 75.0998 bits (183), Expect = 3.640e-12 Identity = 79/267 (29.59%), Postives = 118/267 (44.19%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
K+ +I+DINDNAP+F + + EN +N T+ A D D G NG Y + +N F +D V++T G LD E+ +++ +D G P RSS+ L V+V DTNDN P + + EN P+GT V +++ TD D N K + S A ++F ++ +G I K LDRE + ++AS D G R V VN+ D NDN P + ++
Sbjct: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPA----AVDPDVGTNGVQNYELIK----SQNIFGLD----VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLV--------SNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLAS-----DGGLMPARAM-------VLVNVTDVNDNVPSIDIR 358
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A3R7JVJ3 (Protocadherin-9 (Fragment) OS=Clonorchis sinensis OX=79923 GN=PCDH9 PE=4 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 2.042e-93 Identity = 270/895 (30.17%), Postives = 416/895 (46.48%), Query Frame = 3
Query: 282 DREEYCSKSNKHQTYINSQ-CCGGQ---------------CCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPE----------KTYYKEIL--------ENSKINSRISLPMAYDADDLPFGVESYEIEKPNE-NFDVYFKLMTE--------------------------DFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKP-PRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQD-------IQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE--GTT-----KDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVT-----------INKDPILATDKDEGENGTVEYYISNVVDDMK----------------------------NYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRS---SSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTM-------------EISVTVNILDKNDNSPMMMLKDKPQVKAVN---PEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAM-EKLPPIGDYKTVIVAED--GDFNNSRKQEFLINIH-IKEDPHTLNNKIRTS 2552
DRE C K + SQ CC + CC+++G+ +K +I+I V D+NDN+P F TY KEI+ E + NS +LPMA D D+ G Y I E + YF+L+ D P L+V +DRE I L+A D G+P R ++ + VLDEND P F + +YE+++ E++ G+ LL+++ D DS NNG++ + F + D ++ QL GV L+L LDYE + F+LVA D G+ P SS+A + + V N+ND PP I F+ +P+ YAR+ + E GT D ++C V VTD D+ D I C +E+ F L + T+ +++ RK YE+ + DRE+ ++I C D +G ++L +L + +KD+NDN P F +Y+G V EN VN IV I+ + I A D D G N ++Y + +++ K N F ID TG ++T LD EK K A D P S ++V++ + V+D NDN P +D Y F++ EN P + VG+++ TD D N+R + ++++++ + A Q+ I++ +G I T+ VLDRE QIPF +IA N P + L RD++ E SVTV + D+NDN+P+M+ + + + V+ I +TN I CV FPY F D D+ N +V V M+ N YF ++C + + PP G I D D + ++ F + +H I+E+P L++K S
Sbjct: 127 DRENICDKRMYPERMTVSQACCPLEFTAPAELSLTPTNYPCCVYLGVTVL--SKGTYFIRIDVGDVNDNAPFFTAVNSNTNRNFMSTYRKEIIGKVIISIPEGTPPNSWFALPMATDPDEGMNGAIRYSISTSGEERWAEYFRLLNNLKTASLPVNSTQVNVAWNNAGTTGHLSLGDYSGPGLMVLQTLDRESIADFNLRLVAADLGEPIGRSSTIQLQILVLDENDNAPVFEKTVYEVEVNENQ-AGIPLLYVKANDSDSDNNGRV-VYFMKPSRTDNTVSFDFLRTHIQLVPMNDGVTLRLSQPLDYERSPAFHFDLVAADQGRVPLSSSASILITVRNMNDHPPLIRFFLHGEPLEHDYARLSVTEHFGTVPKQSLHDNLLCHVHVTDADSNLDKIQCNVESGDRKFVLREVMTDQLVQRRKIYELIATTLLDRESTPTQLITIRCQDDDGPSRLVSQKQLHLTLKDVNDNPPKFLQEQYHGYVSENAVNAIVVFHLSNATWKDGIDSNVICAVDNDTGINANIQYLLQRWLEEEKVTKHGTENGSQIEDEKNSVLRYDHSQDANQFYIDPTTGQLRTRTALDCEKQKLYRFVAVAMDKAQPPESRYTATVRVTIEVRDENDNPPVMDKRHYVFKVKENLPRHSRVGQIHTTDADVSPENRRTVYELRDIV-------NINASQMLFIESHTGVIRTRKVLDREEIQQIPFVVIARNEFPYTTQQTL----RDSIQGHSNMNNSKFYDEASVTVEVEDENDNAPVMLPRGSDRQSSTTDGLSTVADITFNTNIKIQHSPCVEFPYYFADADDQSNGEVDVVMEPNPYFEFRLANTLICQISDSAPPAGQSNLRITVSDRPSDLSKVLRRRFTVRMHVIQEEPGGLSDKFEPS 1006
BLAST of Protocadherin-1 vs. TrEMBL
Match: H2KTP1 (Protocadherin-9 OS=Clonorchis sinensis OX=79923 GN=CLF_105398 PE=4 SV=1) HSP 1 Score: 332.028 bits (850), Expect = 1.335e-92 Identity = 269/895 (30.06%), Postives = 416/895 (46.48%), Query Frame = 3
Query: 282 DREEYCSKSNKHQTYINSQ-CCGGQ---------------CCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPE----------KTYYKEIL--------ENSKINSRISLPMAYDADDLPFGVESYEIEKPNE-NFDVYFKLMTE--------------------------DFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKP-PRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQD-------IQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE--GTT-----KDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVT-----------INKDPILATDKDEGENGTVEYYISNVVDDMK----------------------------NYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRS---SSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTM-------------EISVTVNILDKNDNSPMMMLKDKPQVKAVN---PEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAM-EKLPPIGDYKTVIVAED--GDFNNSRKQEFLINIH-IKEDPHTLNNKIRTS 2552
DRE C K + SQ CC + CC+++G+ +K +I+I V D+NDN+P F TY KEI+ E + NS +LPMA D D+ G Y I E + YF+L+ D P L+V +DRE I L+A D G+P R ++ + VLDEND P F + +YE+++ E++ G+ LL+++ D DS NNG++ + F + D ++ QL GV L+L LDYE + F+LVA D G+ P SS+A + + V N+ND PP I F+ +P+ YAR+ + E GT D ++C V VTD D+ D I C +E+ F L + T+ +++ RK YE+ + DRE+ ++I C D +G ++L +L + +KD+NDN P F +Y+G V EN VN IV I+ + I A D D G N ++Y + +++ K N F ID TG ++T LD EK K A D P S ++V++ + V+D NDN P +D + F++ EN P + VG+++ TD D N+R + ++++++ + A Q+ I++ +G I T+ VLDRE QIPF +IA N P + L RD++ E SVTV + D+NDN+P+M+ + + + V+ I +TN I CV FPY F D D+ N +V V M+ N YF ++C + + PP G I D D + ++ F + +H I+E+P L++K S
Sbjct: 127 DRENICDKRMYPERMTVSQACCPLEFTAPAELSLTPTNYPCCVYLGVTVL--SKGTYFIRIDVGDVNDNAPFFTAVNSNTNRNFMSTYRKEIIGKVIISIPEGTPPNSWFALPMATDPDEGMNGAIRYSISTSGEERWAEYFRLLNNLKTASLPVNSTQVNVAWNNAGTTGHLSLGDYSGPGLMVLQTLDRESIADFNLRLVAADLGEPIGRSSTIQLQILVLDENDNAPVFEKTVYEVEVNENQ-AGIPLLYVKANDSDSDNNGRV-VYFMKPSRTDNTVSFDFLRTHIQLVPMNDGVTLRLSQPLDYERSPAFHFDLVAADQGRVPLSSSASILITVRNMNDHPPLIRFFLHGEPLEHDYARLSVTEHFGTVPKQSLHDNLLCHVHVTDADSNLDKIQCNVESGDRKFVLREVMTDQLVQRRKIYELIATTLLDRESTPTQLITIRCQDDDGPSRLVSQKQLHLTLKDVNDNPPKFLQEQYHGYVSENAVNAIVVFHLSNATWKDGIDSNVICAVDNDTGINANIQYLLQRWLEEEKVTKHGTENGSQIEDEKNSVLRYDHSQDANQFYIDPTTGQLRTRTALDCEKQKLYRFVAVAMDKAQPPESRYTATVRVTIEVRDENDNPPVMDKRHHVFKVKENLPRHSRVGQIHTTDADVSPENRRTVYELRDIV-------NINASQMLFIESHTGVIRTRKVLDREEIQQIPFVVIARNEFPYTTQQTL----RDSIQGHSNMNNSKFYDEASVTVEVEDENDNAPVMLPRGSDRQSSTTDGLSTVADITFNTNIKIQHSPCVEFPYYFADADDQSNGEVDVVMEPNPYFEFRLANTLICQISDSAPPAGQSNLRITVSDRPSDLSKVLRRRFTVRMHVIQEEPGGLSDKFEPS 1006
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A183AF39 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS5574 PE=4 SV=1) HSP 1 Score: 333.954 bits (855), Expect = 2.284e-92 Identity = 263/904 (29.09%), Postives = 435/904 (48.12%), Query Frame = 3
Query: 276 PIDREEYCSKS-NKHQTYINSQCCGGQ---------------CCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKT-------YYKEILENSKIN--------SRISLPMAYDADDLPFGVESYEIEKPNEN--FDVYFKLM-------------TEDFVDNKQ-------------PILIVKHQIDREFIDRIEFTLIAVDGGKPPR-KGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKIS-----------INFASSTNQDIQNT-FQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE-----GTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTIN--------KDP---ILATDKDEGENGTVEY-------------------------------------------------YISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRS---SSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLD---YGKDLFRQFRDTM---EISVTVNILDKNDNSPMMMLKDKPQV-----KAVNPEVSFI--KTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLC-AMEKLPPIGDYKTVIVAEDGDFNNSR--KQEFLINIHIKED 2519
P+DRE+ CS + + + S CC CC+F+GI + TK ++I+++D+NDN+P F + Y+ IL + I S I +P A D D+ P G Y +E +EN + YF+L+ + F+ N Q P L++ H +DRE I F L+A D G P + I + VLDEND P F + Y+++I+E++ G+ L+H +V+D D NNG++S + S+ + D T QL GV L++ LDYE +++F+L+A D GQPP S+TA V V V NVND PP I FY +P+ + YAR+ + E + + +IC V VTD D+ +SI+C +E+++ +F+L + TN +++ K YE+ + DRE + + C D + N L N+L++I+ D+ND+APVF+ Y+G+V EN N +V+ + + P + A D D G N + Y ++ N +D + ++ ID+ TG ++T + LD E+ + + A D + S ++ K+ V V+D NDN P ++ Y+F + E P T +G++ D D N+R + ++KN+ + + I+ +G + T+ VLDRE++SQI F ++A N P++ GK + + E+SVTV + D+NDN P+++ + P + + + P V + + STNE P C+ FPY FVD DEG N ++ V ++NN++F D +LC + P +G I +D + ++ K+++ I + ED
Sbjct: 106 PLDREQLCSFALQPERVQLASTCCSKSFDLPADVVMATINQPCCIFLGITIS--TKGTHVLRIQIIDVNDNAPRFNVQLRATNDLPYFANILGKNVIGISESVPPGSWIPIPAAIDNDEGPNGAVRYVLEPLSENLLWTEYFRLINNIRAAGLHANSTSAPFMINDQRKSKSFEPNDYTGPGLLILHPLDREKISSFGFRLVANDLGIPVQLSSSVNIRIVVLDENDNAPTFEKSDYQVQIRENQ-AGVSLVHAKVQDADVDNNGRLSYFMQPTRLDPTMPATSAVSADFLRTHIQLVPVNDGVTLRVSQPLDYEKQPEFTFDLIAVDHGQPPLSATAHVHVSVINVNDYPPMIRFYYHGEPLDRDYARLSVLEQHDSSTSVDNQLICHVHVTDADSDFESISCTVESTERNFFLREVTTNRLIQRSKIYELLTTTKLDREGNARLLILVRCQDGKMANSLASQNQLQLILLDVNDHAPVFTQDHYHGVVPENAANTLVSFSDSGLPSPGQSPTNDVHARDADSGMNALIFYSIVPWSISSSDSDESDSDKSKNSINTTRSTAVQPDRLTNTKSSNSSNHTFLHNPREDAEKFY-IDQTTGQIRTRVALDCEEQQIYRFLVLAIDQAEQLSSRYTATAKVTVTVRDENDNPPVIEQRHYTFAVREGLPRHTRIGQIQSVDADIGSENRRTVYELKNV-------ENFNGSEFILIEAHTGYVRTRQVLDREVTSQISFIVLARNEQPVEEVFRGKQTIQTEKGPTFFDEVSVTVTVEDENDNVPILVRRVPPTLARLLTRELAPSVIDLTFRLSTNETSSP--CIEFPYEFVDDDEGPNGEIEVLLENNNFFEFRLDNSLLCKTTGEQPTMGQMNLFITLQDKPVDKTKTLKRQYTIRVRFIED 996 HSP 2 Score: 67.0106 bits (162), Expect = 3.207e-7 Identity = 97/378 (25.66%), Postives = 146/378 (38.62%), Query Frame = 3
Query: 1320 NRKTYEIKSKIDFDRET--------KTLHFVSIVCSDT---------EGINQ-----------LKQTNKLEVIIKDINDNAPVFSS--------PRYYGIVKENRVN---EIVTINKDPI-LATDKDEGENGTVEYYISNVVDDM--KNYFSIDKN-------------------------------TGVVKTILG-LDYEKIKHVSIEISAKDLGVPVR-SSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTID-----------NESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
NR+ Y++ S + DRE + + S CS + INQ K T+ L + I D+NDNAP F+ P + I+ +N + + + PI A D DEG NG V Y + + +++ YF + N TG IL LD EKI + A DLG+PV+ SSSV + + V D NDN P + S Y ++ EN+ G + V D D D N + L PT+ PA + D N+ + LD E + F +IA +D+G+ + V V++++ ND PM+
Sbjct: 95 NRRWYQLVSTVPLDREQLCSFALQPERVQLASTCCSKSFDLPADVVMATINQPCCIFLGITISTKGTHVLRIQIIDVNDNAPRFNVQLRATNDLPYFANILGKNVIGISESVPPGSWIPIPAAIDNDEGPNGAVRYVLEPLSENLLWTEYFRLINNIRAAGLHANSTSAPFMINDQRKSKSFEPNDYTGPGLLILHPLDREKISSFGFRLVANDLGIPVQLSSSVNIRIVVLDENDNAPTFEKSDYQVQIRENQ-AGVSLVHAKVQDADVDNNGRLSYFMQPTRL-DPTM----PATSAVSADFLRTHIQLVPVNDGVTLRVSQPLDYEKQPEFTFDLIA-----VDHGQPPL-----SATAHVHVSVINVNDYPPMI 456
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A4S2LR15 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005458 PE=4 SV=1) HSP 1 Score: 323.168 bits (827), Expect = 2.261e-89 Identity = 262/881 (29.74%), Postives = 408/881 (46.31%), Query Frame = 3
Query: 282 DREEYCSKSNKHQTYINSQ-CCGGQ---------------CCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPE----------KTYYKEIL--------ENSKINSRISLPMAYDADDLPFGVESYEIEK-PNENFDVYFKLMTE--------------------------DFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKP-PRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQD-------IQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE--GTT-----KDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVT-----------INKDPILATDKDEGENGTVEYYISNVVDDMK----------------------------NYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRS---SSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN--PNPLDYG-KDLFR--------QFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVN---PEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAM-EKLPPIGDYKTVIVAED--GDFNNSRKQEFLINIHIKED 2519
DRE C K + SQ CC + CC+++G+ +K +I+I V D+NDN+P F TY KEI+ E + NS +LPMA D D+ G Y I E + YF+L+ D P +V +DRE I L+A D G+P R ++ + VLDEND P F + +YE+++ E++ G+ LL+++ D DS NNG++ + F + D ++ QL GV L+L LDYE + F+LVA D G+ P SS+ + + V NVND PP I F+ +P+ + YAR+ + E GT D ++C V VTD D+ D I C +E+ F L + T+ +++ RK YE+ + DRE+ ++I C D +G ++L +L + +KD+NDN P F +Y+G V EN VN IV I+ I A D D G N ++Y + ++D + F ID +G ++T LD EK K A D P S ++VK+ + V+D NDN P ++ Y F++ EN P + VG++ TD D N+R + ++++++ + A Q+ I++ +G I T+ VLDRE QIPF +IA N PN + +D R +F D E SVTV + D+NDN+P+M+ + + + V+ I +TN + CV FPY F D D+ N +V V M+ N YF ++C + + PP+G I D D + ++ F + +H+ ++
Sbjct: 149 DRESICDKRLYPERMTVSQTCCPLEFTAPEELSLTPTNYPCCVYLGVTVL--SKGTYFIRIDVGDVNDNAPFFSATNSNTNRNFMSTYRKEIIGKVIISIPEGTPPNSWFALPMATDPDEGMNGAIRYSISTIGEERWAEYFRLLNNLKTASLPVNSTQVNVAWNNAGMTSHLSLGDYSGPGFMVLQTLDRESIADFSLRLVAADLGEPIARSSVIQLQILVLDENDNAPVFEKAVYEVEVNENQ-AGIPLLYVKANDSDSDNNGRV-VYFMKPSRTDNTVSFDFLRTHIQLVPMNDGVTLRLSQPLDYERSPAFHFDLVAADQGRVPLSSSTSILITVKNVNDHPPLIRFFLHGEPLEQDYARLSVTEHFGTVPKQSLHDNLLCHVHVTDADSNLDKIQCNVESGDRKFVLREVMTDQLVQRRKIYELTTTTLLDRESTPTQLITIRCQDDDGPSRLVSQKQLHLTLKDVNDNPPKFIQEQYHGYVFENAVNAIVVLHLSNATWKDGIDSSVICAVDNDTGINANIQYSLQRWLEDEEVTKLGTENGSQTEEEKNSILRYDHSQDATQFYIDPTSGQLRTRTALDCEKQKLYRFVAIAMDKAQPPESRYTTTVKVTIEVRDENDNPPVIEKRHYVFKVKENLPRHSRVGQIQTTDADVSPENRRTVYELRDIV-------NINASQMLFIESHTGVIRTRKVLDREEIQQIPFMVIARNEFPNTMQQTLRDSIRVHSNMNNSKFYD--EASVTVEVEDENDNAPVMLARGSDRQSSTTDGLSTVADITFNTNIKVQQSPCVEFPYYFADADDKSNGEVDVVMEPNPYFEFRLANTLICQISDSAPPVGQSNLRITVSDCPSDLSKVLRRRFTVRVHVIQE 1016
BLAST of Protocadherin-1 vs. TrEMBL
Match: A0A4S2LR01 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005458 PE=4 SV=1) HSP 1 Score: 323.553 bits (828), Expect = 5.763e-89 Identity = 262/881 (29.74%), Postives = 408/881 (46.31%), Query Frame = 3
Query: 282 DREEYCSKSNKHQTYINSQ-CCGGQ---------------CCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPE----------KTYYKEIL--------ENSKINSRISLPMAYDADDLPFGVESYEIEK-PNENFDVYFKLMTE--------------------------DFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKP-PRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQD-------IQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINE--GTT-----KDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVT-----------INKDPILATDKDEGENGTVEYYISNVVDDMK----------------------------NYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRS---SSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN--PNPLDYG-KDLFR--------QFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVN---PEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAM-EKLPPIGDYKTVIVAED--GDFNNSRKQEFLINIHIKED 2519
DRE C K + SQ CC + CC+++G+ +K +I+I V D+NDN+P F TY KEI+ E + NS +LPMA D D+ G Y I E + YF+L+ D P +V +DRE I L+A D G+P R ++ + VLDEND P F + +YE+++ E++ G+ LL+++ D DS NNG++ + F + D ++ QL GV L+L LDYE + F+LVA D G+ P SS+ + + V NVND PP I F+ +P+ + YAR+ + E GT D ++C V VTD D+ D I C +E+ F L + T+ +++ RK YE+ + DRE+ ++I C D +G ++L +L + +KD+NDN P F +Y+G V EN VN IV I+ I A D D G N ++Y + ++D + F ID +G ++T LD EK K A D P S ++VK+ + V+D NDN P ++ Y F++ EN P + VG++ TD D N+R + ++++++ + A Q+ I++ +G I T+ VLDRE QIPF +IA N PN + +D R +F D E SVTV + D+NDN+P+M+ + + + V+ I +TN + CV FPY F D D+ N +V V M+ N YF ++C + + PP+G I D D + ++ F + +H+ ++
Sbjct: 127 DRESICDKRLYPERMTVSQTCCPLEFTAPEELSLTPTNYPCCVYLGVTVL--SKGTYFIRIDVGDVNDNAPFFSATNSNTNRNFMSTYRKEIIGKVIISIPEGTPPNSWFALPMATDPDEGMNGAIRYSISTIGEERWAEYFRLLNNLKTASLPVNSTQVNVAWNNAGMTSHLSLGDYSGPGFMVLQTLDRESIADFSLRLVAADLGEPIARSSVIQLQILVLDENDNAPVFEKAVYEVEVNENQ-AGIPLLYVKANDSDSDNNGRV-VYFMKPSRTDNTVSFDFLRTHIQLVPMNDGVTLRLSQPLDYERSPAFHFDLVAADQGRVPLSSSTSILITVKNVNDHPPLIRFFLHGEPLEQDYARLSVTEHFGTVPKQSLHDNLLCHVHVTDADSNLDKIQCNVESGDRKFVLREVMTDQLVQRRKIYELTTTTLLDRESTPTQLITIRCQDDDGPSRLVSQKQLHLTLKDVNDNPPKFIQEQYHGYVFENAVNAIVVLHLSNATWKDGIDSSVICAVDNDTGINANIQYSLQRWLEDEEVTKLGTENGSQTEEEKNSILRYDHSQDATQFYIDPTSGQLRTRTALDCEKQKLYRFVAIAMDKAQPPESRYTTTVKVTIEVRDENDNPPVIEKRHYVFKVKENLPRHSRVGQIQTTDADVSPENRRTVYELRDIV-------NINASQMLFIESHTGVIRTRKVLDREEIQQIPFMVIARNEFPNTMQQTLRDSIRVHSNMNNSKFYD--EASVTVEVEDENDNAPVMLARGSDRQSSTTDGLSTVADITFNTNIKVQQSPCVEFPYYFADADDKSNGEVDVVMEPNPYFEFRLANTLICQISDSAPPVGQSNLRITVSDCPSDLSKVLRRRFTVRVHVIQE 994
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 229.18 bits (583), Expect = 1.363e-61 Identity = 195/702 (27.78%), Postives = 324/702 (46.15%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFN-KPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN---NDYFSLTPDYGMLCAMEKLP-PIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP + EN+ + + ++P A D D GV Y++ E F L + K P LIV +DRE D + T+ AVDGG P R + + + D ND PQF + YE ++ E+ G +L ++ D D G NG+I +++ + Q+ ++ +++K LD E I+ + F+++A+D G P+SST V + VT+ ND+ P + + S A I+E + LV+V+D D +++ + F L ++V +N+K Y +++ D E + V IV D+ G L TN L V + D NDN+P+FS P + +EN+ E V ++A D D G N + Y I + D + F ID ++G V+ LD E + ++A D GVP + +++ V D NDN P+ LS YSF + EN P + VG V V D D N + + P +G F + N +G I + + DRE S F + A +D G+ + + VT+N+LD+NDN+P++ + ++P + S E + E D+D G N+++ ++ ++ F ++P G + ++L G ++V SR L++I++ E
Sbjct: 125 NDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEA-SALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDP-VPKMLQIERSTGIISVK--GPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVAN--ISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSV-DNKKKYFLQTTTPLDYERIRDYRVEIVAVDS-GNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVL----DVIALDADSGTNAELVYSI--IADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVE------PDVGN-------FVVQNGTGTILSSISFDREKESSYTFRLKA-----VDGGEPPRSSY-----VGVTINVLDENDNAPVVTKPSNSSFRRLSPLAA--PDSVVEVVEAE----------DIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYVNE 777 HSP 2 Score: 126.716 bits (317), Expect = 4.065e-29 Identity = 148/558 (26.52%), Postives = 235/558 (42.11%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYIS------------NVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++V D ND PQF + + ++E+ G + D+D+ NG + + ++ + Q++ +LI LD E + Y + A D G P R S+AL+ V +T+ ND+ P QF K S A ++E + + VK D D + EIE + + + +L+ R T I K DRE + ++ D +G + T + + + D NDNAP GI + + I++D + T DKDEGEN V ++ + VD+ K YF ++T LDYE+I+ +EI A D G P SS+ L V V DTNDN P + E E G V V D D+ N + + ++ +F ID SG++ + LDRE + F + A+ D G R +V + +LD+NDN P ML SF S EN+ P + V + D+D+GEN++V+++++
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAP-----QFEK--SSYEAE--VSENSPVGYSVLQVKANDSDLGPNG---EIEY---TIHQASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARD-KGPSPKSSTTYVSIEVTDQNDNAPAV---EIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYF--------LQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVY----------SIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAA-----DKGVPSHRG-----TATVVIKVLDRNDNDPKFMLS----------SYSF---SVLENMPPLSPVGMVTVL-DMDKGENAQVQLSVE 615 HSP 3 Score: 88.9669 bits (219), Expect = 1.707e-17 Identity = 104/369 (28.18%), Postives = 156/369 (42.28%), Query Frame = 3
Query: 1326 KTYEI-KSKIDFDRET-------KTLHFVSIVCSDTEGI-NQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI----DKNTGVVKTI-LG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTP 2384
KT EI ++I DRET F+ S T+ I NQ + + + ++DINDN P F SP V+EN + I + ATD+D NG ++Y +S + FS+ D+ + + I LG LD E + I+A D G P R SS L V + D NDN P+ + S Y E+ EN P+G V +V D D N + + S P ++ I+ +G I K LDRE S F +IA + P + V++ + D+NDN+P + +++ + + P D DEGEN+ V + + F L P
Sbjct: 69 KTGEIFTTEIPIDRETLKDCRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQ----ATDRDTERNGVLKYDLS-AGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQ---------ASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTY----------VSIEVTDQNDNAPAV------EIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRP 407
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 230.335 bits (586), Expect = 1.541e-61 Identity = 195/702 (27.78%), Postives = 324/702 (46.15%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFN-KPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVD-DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN---NDYFSLTPDYGMLCAMEKLP-PIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP + EN+ + + ++P A D D GV Y++ E F L + K P LIV +DRE D + T+ AVDGG P R + + + D ND PQF + YE ++ E+ G +L ++ D D G NG+I +++ + Q+ ++ +++K LD E I+ + F+++A+D G P+SST V + VT+ ND+ P + + S A I+E + LV+V+D D +++ + F L ++V +N+K Y +++ D E + V IV D+ G L TN L V + D NDN+P+FS P + +EN+ E V ++A D D G N + Y I + D + F ID ++G V+ LD E + ++A D GVP + +++ V D NDN P+ LS YSF + EN P + VG V V D D N + + P +G F + N +G I + + DRE S F + A +D G+ + + VT+N+LD+NDN+P++ + ++P + S E + E D+D G N+++ ++ ++ F ++P G + ++L G ++V SR L++I++ E
Sbjct: 161 NDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPE-ASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDP-VPKMLQIERSTGIISVK--GPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVAN--ISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSV-DNKKKYFLQTTTPLDYERIRDYRVEIVAVDS-GNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVL----DVIALDADSGTNAELVYSI--IADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVE------PDVGN-------FVVQNGTGTILSSISFDREKESSYTFRLKA-----VDGGEPPRSSY-----VGVTINVLDENDNAPVVTKPSNSSFRRLSPLAA--PDSVVEVVEAE----------DIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYVNE 813 HSP 2 Score: 129.028 bits (323), Expect = 1.010e-29 Identity = 147/558 (26.34%), Postives = 234/558 (41.94%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYIS------------NVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
++V D ND PQF + + ++E+ G + D+D+ NG + + ++ + Q++ +LI LD E + Y + A D G P R S+AL+ V +T+ ND+ P QF K Y ++E + + VK D D + EIE + + + +L+ R T I K DRE + ++ D +G + T + + + D NDNAP GI + + I++D + T DKDEGEN V ++ + VD+ K YF ++T LDYE+I+ +EI A D G P SS+ L V V DTNDN P + E E G V V D D+ N + + ++ +F ID SG++ + LDRE + F + A+ D G R +V + +LD+NDN P ML SF S EN+ P + V +D+D+GEN++V+++++
Sbjct: 155 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAP-----QFEK---SSY-EAEVSENSPVGYSVLQVKANDSDLGPNG---EIEY---TIHQASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARD-KGPSPKSSTTYVSIEVTDQNDNAPAV---EIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYF--------LQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVY----------SIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAA-----DKGVPSHRG-----TATVVIKVLDRNDNDPKFMLS----------SYSF---SVLENMPPLSPVGM-VTVLDMDKGENAQVQLSVE 651 HSP 3 Score: 90.5077 bits (223), Expect = 6.593e-18 Identity = 108/374 (28.88%), Postives = 164/374 (43.85%), Query Frame = 3
Query: 1326 KTYEI-KSKIDFDRET-------KTLHFVSIVCSDTEGI-NQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSI----DKNTGVVKTI-LG-LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTN--ENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSLTP 2384
KT EI ++I DRET F+ S T+ I NQ + + + ++DINDN P F SP V+EN + I + ATD+D NG ++Y +S + FS+ D+ + + I LG LD E + I+A D G P R SS L V + D NDN P+ + S Y E+ EN P+G V +V D D N + + S P ++ I+ +G I K LDRE S F +IA + P + V++ + D+NDN+P + +++ + ++T ++ NI + V V D DEGEN+ V + + F L P
Sbjct: 105 KTGEIFTTEIPIDRETLKDCRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQ----ATDRDTERNGVLKYDLS-AGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQ---------ASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTY----------VSIEVTDQNDNAPAV------EIRGIG-----LRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRP 443
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh1b (protocadherin 1b [Source:ZFIN;Acc:ZDB-GENE-091015-2]) HSP 1 Score: 225.328 bits (573), Expect = 3.616e-60 Identity = 178/608 (29.28%), Postives = 288/608 (47.37%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVA-LKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI--VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDM-KNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVS 2243
NDN+P FP I EN+ + + S+P+A D D G+ Y++ ++ ++ F L D D K P LIV +DRE D + ++ +DGG PPR + + + D ND P+F + YE ++ E+ G +L ++ D D G NG+++ +F +Q N +L H +++ +D E + F++ A+D G +SS A+V + V + ND+ P+I F ++ + ++E + LV+V+D D +++ + F L + + RK Y +++ D E + + IV D+ G L TN L+V + D+NDNAPVF SP Y + +EN+ + V ++ATD D G N + Y I + D K F I+ NTG V+ + LD E + + A D GVP + ++V V D NDN P+ L+ YSF + EN P + VG V V D D N + + +P + F I N +G I + + DRE S F + A + G D R + + +T+N+LD+NDN+P + K + P S
Sbjct: 137 NDNTPQFPSPILELAIPENTYVGAHYSIPVAMDKDAGSNGIADYKLNSGSDAMNL-FSLQVADNTDEKVPQLIVLGNLDREQRDTYDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSF----HQPSPNVQRLLHIDHNTGIIQVKGSVDREEVPLLKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGL-VAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASASDSTSKRK-YFLQTTTPLDYERIKEYRIEIVAVDS-GNPALSSTNSLKVQVTDMNDNAPVF-SPSLYEVDFAEENQPGDKVL----DVVATDADSGTNAELLYSI--ITDSATKGLFDINPNTGEVRVMNQLDREYKERYEFHVEAADKGVPSLKGTATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSPVGMVTVIDADKGENAHVQL-------------SVEPENGKFVIQNGTGTILSSISFDREKESTYTFRLKAVD------GGDPPR----SSYVGITINVLDENDNAPYVTKPSNSSYKFLQPLTS 706 HSP 2 Score: 134.806 bits (338), Expect = 1.422e-31 Identity = 159/564 (28.19%), Postives = 238/564 (42.20%), Query Frame = 3
Query: 717 GKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS---QTLHGVA-LKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYISNVVDDMKNYFSIDKNTG----VVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK 2357
G PR + +I ++ DEND PQF I E+ I E+ G DKD+G+NG ++ ++ D N F L T V L ++ LD E + Y ++ D G PPR S+AL+ + +T+ ND+ P + ++ E T + VK DDD A+ SF+ + +L + T I+ K DRE L S+ D G + + +KD NDNAP R +G+V + I +++D + T DKDEGEN V ++ V S +T ++T LDYE+IK IEI A D G P SS+ L V V D NDN P S Y + E G V V TD D+ N + + ++ T +F I+ +G++ LDRE + F + A+ D G + +V V +LD+NDN P ML SF S EN+ P + V +D D+GEN+ V+++++
Sbjct: 121 GSGPRLIEGRI--EIQDENDNTPQFPSPILELAIPENTYVGAHYSIPVAMDKDAGSNGI--ADYKLNSGSDAMNLFSLQVADNTDEKVPQLIVLGNLDREQRDTYDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMA---------ENTPVGQSVLQVKANDDDLGANGQVT------YSFHQPSPNVQRLLHIDHNTGIIQVKGSVDREEVPLLKFSVQARDN-GPQAKSSKAMVTITVKDRNDNAPSIRI-RGFGLVAHE--DGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASASDSTSKRKYFLQTTTPLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLDVVATDADSGTNAELLY----------SIITDSATKGLFDINPNTGEVRVMNQLDREYKERYEFHVEAA-----DKGVPSLKG-----TATVVVRVLDRNDNDPKFMLNG----------YSF---SVLENMPPLSPVGM-VTVIDADKGENAHVQLSVE 627 HSP 3 Score: 62.003 bits (149), Expect = 3.303e-9 Identity = 67/230 (29.13%), Postives = 91/230 (39.57%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELL--------HLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAK--DFGQPPRSSTALVEVFV 1091
NDN P F Y +LEN S + + DAD +E N F + N ++ DRE F L AVDGG PPR I + VLDEND P Y K S L+ L + ED D+G N ++ S T + F++S T + L + +++ LV K D G+P R +TALV +FV
Sbjct: 581 NDNDPKFMLNGYSFSVLENMPPLSPVGMVTVIDADKGENAHVQLSVEPENGKF----------VIQNGTGTILSSISFDREKESTYTFRLKAVDGGDPPRSSYVGITINVLDENDNAP------YVTKPSNSSYKFLQPLTSPDTRVEKVDAEDIDTGLNAEL---VYSITGGNPHGLFRISSTDGEITLAKEFTRKHNGLHR----LVVKVSDKGKPSRHTTALVHIFV 787
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh7a (protocadherin 7a [Source:ZFIN;Acc:ZDB-GENE-120206-1]) HSP 1 Score: 208.379 bits (529), Expect = 8.322e-55 Identity = 188/701 (26.82%), Postives = 307/701 (43.79%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEI--------------------------EKPNENFDV------YFKLMTEDFVDN-KQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV--NEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL---TPDYGMLCAMEKL 2417
NDN+P+FP + EN I + LP A D D G++ YE+ + E V F+L D D KQP LIVK +DRE D E L DGG PPR + + + + D ND P+F + +YE ++ E+ G +L +R D+D G NG++ F ++T + ++ +L + L ++ ++D E +++ F + A+D GQPPR+ A V + V + ND+ P + + + + + A + + E D + LV+V+D D + ++TC + F L N N+K + + + D E + V+IV D+ L + L V + DIND+AP F+ EN +VT ++A D D G+N + Y + V+ F ID + G ++ LD E+ + + A+D G P S ++V V D NDN P+ ++F + EN + VG V VTD D N + + ++ G Q ++F+I+N +G I++ DRE S F + A + G + R T+ + VT D+NDN+P + + P S +T V + D D G N+ +R + + F L P G++ E L
Sbjct: 140 NDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIDRYELVQDSRDQRRPASATMPAGINNGAGDRRRGQEAGSVPAGRSNVFELQVADTPDGQKQPQLIVKGPLDREARDSYELVLRVRDGGNPPRSSQALLRVAITDVNDNSPRFERAVYEAEMGENTPPGTPVLQVRASDRDIGVNGQVEYVFGAAT-ESVRRLLRLDEASG--WLSVLHRIDREEVSQLRFTVTARDRGQPPRTDRATVILNVRDENDNVPVVEIRKIGRILVRDGAAM-VPENVLVDTPVALVQVSDRDQGENGAVTCTV-VGDVPFTLKPAGEN---RNKKKFFLHTSALLDYEATRDYTVTIVAVDSG-SPSLSSNSTLMVRVVDINDHAPTFAQSLVEVHFAENNAPGERVVT-----VVAADADSGKNAEIAYSLDPSVN---GAFYIDADNGDIRATGALDREQRERYEFRVIARDKGSPSLQGSATVVVQVTDRNDNAPKFVQEVFTFYVKENLLANSPVGMVTVTDADEGENAELCLFVEEDEEEEEAGGRRQ---ELFSIENNTGTIFSAASFDRESRSTYTFRVRAVD------GGEPPRSATATVSLFVT----DENDNAPSVTAPANESYTLL-PPASGART-----------VVRTVMASDGDAGSNADLRYALVGGNPFQLFEIGPSSGVITLAEPL 798 HSP 2 Score: 56.6102 bits (135), Expect = 1.622e-7 Identity = 64/262 (24.43%), Postives = 103/262 (39.31%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELL--HLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQT--LHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVI 1205
NDN+P F ++ + + EN NS + + DAD+ +E+ E + + ++N + DRE F + AVDGG+PPR + L V DEND P + E +G + + D D+G+N + N FQL + GV + L L+ + + D G P +TALV VF +N+S N + Q ++ GT + +V+
Sbjct: 614 NDNAPKFVQEVFTFYVKENLLANSPVGMVTVTDADEGENAELCLFVEEDEEEEEAGGRRQELFSIENNTGTIFSAASFDRESRSTYTFRVRAVDGGEPPRSATATVSLFVTDENDNAPSVTAPANESYTLLPPASGARTVVRTVMASDGDAGSNADLRYALVGG------NPFQLFEIGPSSGV-ITLAEPLERRHRGLHRLVVRVNDSGVPSLCATALVHVF---INESLTNATL------VDAQCEHVHQRTGTQRCIVV 859
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:103034658]) HSP 1 Score: 207.608 bits (527), Expect = 3.202e-54 Identity = 200/742 (26.95%), Postives = 333/742 (44.88%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEI-------------------EKPNENFD------VYFKLMTEDFVDN-KQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTK-------DMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV-NEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL---TPDYGMLCAMEKLPP--IGDYKTVIVAEDGDFNNSRKQEFLINIHIKEDPHTLNN 2537
NDN+P+FP + EN I + LP A D D G+E YE+ FD F+L D D KQP LI+K +DRE D E TL DGG P R + + + + D ND P+F + +YE + E+ G +L L+ D D G NG+I F ++T + ++ +L ++ L ++ ++D E +++ F ++A+D GQPP++ A + + + + ND+ PNI ++ RIY+ +G D I LV+V+D D + +TC + F L N+K Y + + D E + V IV D+ + + + V + DINDN P+F+ EN E V ++A D D G+N + Y + + V+ + FSID ++G ++ LD E+ + ++ AKD GVPV S ++V V D NDN+P+ ++F + EN + VG V V D D N + + + ++IF+I+N +G I++ V DRE + F + A + G D R + +V++ ++D+NDN P + +N + + S+N V I D D G N+ + ++ + F L PD G++ + KL G ++ V+ D S+ L+++++ E TL+N
Sbjct: 133 NDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDGAESSVRRLGSASTDAHSGKRRFDDAQSRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPARSSQAILRVMITDVNDNSPRFEKSVYEADLPENSSPGAPILQLKAMDADVGVNGQIEYVFGAAT-ESVRRLLRLDESTG--WLSVLHRIDREEVSQLRFTVMARDRGQPPKTDKATMIINIKDENDNVPNIDI--------RKIGRIYLRDGVANVAEDVVVDTPIALVQVSDRDKGPNGVVTCTV-VGDVPFQLKPASEIEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLI-VKVGDINDNPPIFTKSTVEVSFPENNAPGERVAT----VVALDADSGKNAEIFYSLDSSVNGI---FSIDADSGDIRVNTILDREQTERYEFKVIAKDKGVPVMQGSATVVVLVADKNDNEPKFMQDVFTFYVKENLQPNSPVGMVTVMDSDKGQNAEMSLYIEE-------------EEEIFSIENNTGTIFSTVAFDREQKTTYSFRVKAVD------GGDPPR----SATATVSLFVMDENDNPPSVTFP-------INSSYTLLPPSSN-----IRTVVRTVIATDTDTGVNADLSYSIIGGNPFKLFEIDPDTGVISLVSKLEQKHFGLHRLVVQVNDSGV-PSQSTTTLVHVYVNE---TLSN 815 HSP 2 Score: 101.293 bits (251), Expect = 3.313e-21 Identity = 118/455 (25.93%), Postives = 192/455 (42.20%), Query Frame = 3
Query: 477 ILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLM----TEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSP---RYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVD 1820
+ E+ +++ I+L D D P GV + + DV F+L E ++ K+ L +D E + ++AVD G P +I+KV D ND P F++ E+ E+ G + + D DSG N +I + SS N F + + + I LD E +Y F ++AKD G P +A V V V + ND+ P + F Y+ E + + +V V D D + ++ S Y+ + +EN T I S + FDRE KT + + D G T + + + D NDN P + P Y + + + +V ++ATD D G N + Y I + + F ID +TGV+ + L+ + + + D GVP +S++ + V V +T N VD
Sbjct: 402 VAEDVVVDTPIALVQVSDRDKGPNGVVTCTVVG-----DVPFQLKPASEIEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDINDNPPIFTKSTVEVSFPENNAPGERVATVVALDADSGKNAEIFYSLDSSVN----GIFSIDADSGDIRVNTI--LDREQTERYEFKVIAKDKGVPVMQGSATVVVLVADKNDNEPKFMQDVFT---------FYVKENLQPNSPVGMVTVMDSDKG--------QNAEMSLYIEEEEEIFSIEN-NTGTIFSTVAFDREQKTTYSFRVKAVDG-GDPPRSATATVSLFVMDENDNPPSVTFPINSSYTLLPPSSNIRTVVRT----VIATDTDTGVNADLSYSI--IGGNPFKLFEIDPDTGVISLVSKLEQKHFGLHRLVVQVNDSGVPSQSTTTLVHVYVNETLSNSTVVD 820 HSP 3 Score: 92.8189 bits (229), Expect = 1.253e-18 Identity = 147/537 (27.37%), Postives = 217/537 (40.41%), Query Frame = 3
Query: 759 VLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNG-----------KISINFASSTNQDIQNT---------------FQLSQTLHG---VALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVL------ENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVI--IKDINDNAP---VFSSPRYYGIVKENRVNEIVTINKDPIL--ATDKDEGENGTVEYYI-----------SNVVDDM--KNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNIL--DKNDNSPMMM 2198
+LD ND P F + + ++E+ G L D+D G NG + S+ S + D + Q++ T G L + LD E + Y L +D G P RSS A++ V +T+VND+ P +F K + + + E ++ I +K D D + +IE Y+ T +V E+ + +ID + E L F +++ D Q +T+K +I IKD NDN P + R Y V E V ++ L +D+D+G NG V + S + DM K YF + T LDYE ++ ++ I A D G P SS+ LIV V D NDN P S EN G V V D D+ N + +L +S + IF+ID +SG I +LDRE + + F +IA D G + M+ S TV +L DKNDN P M
Sbjct: 129 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDGAESSVRRLGSASTDAHSGKRRFDDAQSRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPARSSQAILRVMITDVNDNSP-----RFEKSVYEA----DLPENSSPGAPILQLKAMDADV---GVNGQIE------YVFGAATESVRRLLRLDESTGWLSVLHRIDRE-EVSQLRF-TVMARDR---GQPPKTDKATMIINIKDENDNVPNIDIRKIGRIYLRDGVANVAEDVVVDTPIALVQVSDRDKGPNGVVTCTVVGDVPFQLKPASEIEGDMNKKKYF--------LHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDINDNPPIFTKSTVEVSFPENNAPGERVATVVALDADSGKNAEIFY----------SLDSS--VNGIFSIDADSGDIRVNTILDREQTERYEFKVIAK-----DKGVPV-------MQGSATVVVLVADKNDNEPKFM 610
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 208.764 bits (530), Expect = 1.094e-55 Identity = 211/711 (29.68%), Postives = 323/711 (45.43%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL-MTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINF-----ASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQAD-SITCEIETSQESFYLNALK--TNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV--NEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEKLPPI--GDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P F + EN+ R + A D D GV YE+ + F+L +TE K P L+V+ +DRE E L AVDGG PP G + + V D ND P F Q ++I E+ G ++ L D+D+G+N ++ + + Q + F+L Q V + + L+ E Y ++A D G P +TA V V VT+VND+ P I P++ IYI+E + ++ + L+ V+D D A+ ++TC I + F L L +LE R+T D ETK + V I +D G L +T + + + D NDNAPVF+ P Y V EN V ++T++ ATD+D +N + Y++ D F +D TG++ LD EK + S I AKD G+PV + +IVNV D NDN+P L+ + F + EN P + VG V V D D N + + LGT Q+F+ID ESG I + V DRE + A++ G + R + + V ++++D NDNSP++++ N F+ T P VT VD D N+++R V ++ F + P G + ME L G ++ V+ D L+++ + E
Sbjct: 147 NDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGL--LNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVN---GVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETRET--------LDYETKNEYVVQIKAADA-GATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVS-----ATDRDMDKNAEMVYFLG---PDAPTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLS---------ILGTDN--RQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATD------GGEPVR----SSTVKVVIHVMDINDNSPIVLMPPS------NTTYKFVVPRT----LPGTIVT-EVSAVDNDAEINAELRYHIVGGNPHNLFHIDPVIGNITLMEPLTETHHGLHRLVVRVSDIGIAVQHHAVALVHVFVNE 803 HSP 2 Score: 66.2402 bits (160), Expect = 3.180e-11 Identity = 66/231 (28.57%), Postives = 106/231 (45.89%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL-ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG-----------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNP 2096
++ + ++DINDNAP F++P V EN + PI A D D NG Y + + F + V +T G LD E+ + + + A D G P S S L +NV DTNDN P D + + E+ EN P+GT+V +++ +D+D N + + + G+ Q ++F +D SG + +L+RE S I+A++ P
Sbjct: 138 EVRINVEDINDNAPAFAAPVLTVSVPEN----APAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELS----VTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTG---GAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGP 357
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 182.57 bits (462), Expect = 8.773e-47 Identity = 194/721 (26.91%), Postives = 314/721 (43.55%), Query Frame = 3
Query: 237 SFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPN--ENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQL-SQTLHGVALKLISK---LDYETINKYSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQES--FYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND 2366
S + GR+ IDREE + + NS G+ + + + D+N+++P F +Y I E+ +NSR A D D G YEI + N E F + F D + L V++++DRE + T+ A+D G P + + VLD ND +P F+ Y E + G + ++ D D+G+NG ++ +F + Q F+L S+T +L++ + + +SF++VA D G+P P A V+VFV +VND+PP QF K + + ++E + + V +D D+ ++ I E F ++A T +I DRE +T + +V + G + L + + V + D NDN P F+ S ++ RV E++ + A+D+D G +G V Y I V + F+ID++TG V LD+E + + +SA+D G P RSS+ L+V+V+D NDN P + EN PIGT V V D D D+N + + PG FTID ESG+I T +DRE++ + F + + K + R + +VTV + D+NDN+P + V + + + + D DE EN+ VR + D
Sbjct: 705 SIEWSGGRIFTANAIDREEQAFY--QLRVVANSGGVAGEASVSVLV----------------HDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGI--------FPDGQ---LYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSF-----EKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPP-----QFAKSVYQAS----VSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDA----------STGQITLLGSLDRE-ETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLIT----LTASDEDTGPSGDVRYAI--VAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPG----------AHFTIDPESGEICTAAEIDREVTGGL-FEVTVRATD-----KAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAAAGSVVGTLQAS--------------DPDEAENAAVRYAVTGGD 1335 HSP 2 Score: 147.517 bits (371), Expect = 6.071e-36 Identity = 175/659 (26.56%), Postives = 268/659 (40.67%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEIL-ENSKINSRISLPMAYDADDLPFGV--ESYEIEKPNENFDVYFKLMTEDFVDNKQPI-LIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETS--------QESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPAD--QIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND 2366
NDN+P+FPE + E++ + ++ L A D D P GV +Y+I NE +L+ V + + L +DRE + A DGG P R G+ ++ + V D ND P F + Y + E G L L + G +++ F T + +T Q LD+E +Y+ +L A D G PP S A + + +VND+ P I F + P ++ + ++E V LV VTD ADS T E S + F L+A + + ++ S++ DRE ++ ++I+ SD T L V + D+ND+AP F+ Y + E + KD + A D D G N + Y I V + +FS+D++TG+V T +D E V + ISA+D G +++ L V + D ND P + Y EN G +V V+ D D N ++ PA ++F +D+ +GK+ T LDRE + P + A + G VTV + D NDN P+ P F NE P D D G N VR + D
Sbjct: 17 NDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEG----RLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAALRDLLHRGR-----GPLAVPFDPKTG--MVSTRQ--------------PLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFV-YLPPAARSAS---VDESAAPGTVAALVTVTD----ADSPTANGELSVSIVGGNERGHFVLHAPGVPGL----RVLKVASQL--DRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEG--APAGSYVKD-VTAMDADSGLNAKLRYSI--VSGNDLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDM----------PAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGS----------TAKVTVVVGDLNDNHPVFY-----------PVQYFASILENE---PGGTAVTTVTATDPDRGANGTVRYQLTAGD 597 HSP 3 Score: 142.51 bits (358), Expect = 2.017e-34 Identity = 157/605 (25.95%), Postives = 248/605 (40.99%), Query Frame = 3
Query: 645 LIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPI--SKQYARIYINEGTTKDMVICLVKVTDDDNQAD-SITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRE-------TKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKN----NDYFSLTPDYGMLCAMEKL 2417
+ + IDRE + ++A GG G+ + + V D N+ P F + YE+ I E E +R DKDSG NG++ + F Q L + +LD ET +YS + A D G P SS+ V V V +VND NKP+ S Y + E +V V+ TD D ++ +T E Q +F L++ +T I S FDRE + F S+V +D L+ ++V ++D+NDN P F+ Y V E+ N + + A+D DEG NG + Y I+ + K F++D +TG + + LD E+ ++ +SA D G ++S + V V D NDN P S S + E+ +G + + +D+DT ++ G T T F ID +G ++ LD E + A +D R R + I V V++ D NDN P + D + S ENI P D D N ++ ++ +F++ P+ G +C ++
Sbjct: 713 IFTANAIDREEQAFYQLRVVANSGGV---AGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFPDGQ------LYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVND----------NKPLFNSSSYVFHFCEEQEVGSLV-GAVQATDADAGSNGGVTYSFEKPQVNFELDS----------ETGRIASLRVFDREALIRQGGAASFSF-SVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLR---VTASDVDEGVNGALRYAINEGNEGGK--FTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTG----PSGDVRYAIVAGNTHAT-------FAIDRSTGSVFLARRLDFETQRLYRLNVSA---------EDGGRPPRSSATILV-VHVRDFNDNPPAFLPGD-------------VFASIMENI-PIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEI 1246 HSP 4 Score: 139.043 bits (349), Expect = 2.552e-33 Identity = 159/603 (26.37%), Postives = 251/603 (41.63%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIY------EIKIKESEMTGLELLHLRVEDKDSGN-NGKISINFASSTNQDIQNTFQL-SQTLHGV-ALKLISKLDYETINKYSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEY-YISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKD 2207
NDN P F + Y + E+S + + + DL + + V F D K ++ + +D E + +L A DGG PP G+ ++++LD ND +P + +Y + ES G + V D DS NG++S++ + F L + + G+ LK+ S+LD E I Y+ ++A D G+P RS+TA + V+V +VND P + ++EG + V D D+ + ++ S S N L +V E+ K+D RE + ++I D +G L V + D+ND P+F+ +Y EN + + ++ + A D D GENGTV Y + ++ + F +D TG V T+ LD E+++ + + A+D G P S+ K+ V V D NDN P Y + ENEP GT V V TD D N T G + F ++ +G + T+V LDRE + + A LD G R VT+ + D D P D
Sbjct: 130 NDNPPAFEKPAYRASVAEDSPVGAALR--------DL--------LHRGRGPLAVPF--------DPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAI-RFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNER---GHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRF---------ALSAYAAALSEGAPAGSYVKDVTAMDADS---GLNAKLRYSIVSG--NDLGWFSVDESTGLVTTDGKVD--REVASSVVLNISAQD-QGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVS---VSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQL--------TAGDA----ARFQVNAVTGAVSTRVSLDREERAVYQLQVTA-----LDGG-----HLRARSPAIVTITVADAQDTPPTFARDD 662 HSP 5 Score: 131.339 bits (329), Expect = 5.203e-31 Identity = 150/590 (25.42%), Postives = 249/590 (42.20%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQES--FYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
ND++P F Y + E + S + A DAD Y I N+ +F VD ++ ++DRE + + A D G P+ T + + +LD ND P F+Q Y E+ + GL ++ + D D G NG + NF + F+L +L G L S LD E + +Y + A+D G PP STA V V V ++ND+ P VFY P+ + +A I NE + V TD D A+ T+ ++ F +NA+ T + +++ DRE + ++ + + D G + + + + + D D P F+ Y +V EN + + + A+ D N V Y I V D + FSI+ + G + T +D E+ + + A GV + + V V D N++ P D + Y + E+EP+ + V TDKD+ N + +G ++ + G++Y + LDRE + + A +D G + + ++V V +LD NDN P+
Sbjct: 335 NDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLG--WFS------VDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRL-DSLTGKVTTLKS-LDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHP--VFY----PV-QYFASILENE--PGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAV----------TGAVSTRVSLDREERAVYQLQVTALDG-GHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGS---VSASTLD--LNANVTYLI--VSGDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGGV---AGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYE----------IGEGNGGEKFGIFPD--GQLYVRYELDRETREEYSLTVSA-----MDTGVEPL-----SSSVTVNVTVLDVNDNKPLF 862 HSP 6 Score: 128.642 bits (322), Expect = 3.554e-30 Identity = 145/586 (24.74%), Postives = 247/586 (42.15%), Query Frame = 3
Query: 642 ILIVKHQIDREFIDRIEFTLIAVDGGKP-PRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK---NNDYFSLTPD 2387
+L V Q+DRE I T++A D GKP R +++ V D ND P+F+ Y + E G + + D DSG N K+ + S + F + ++ V K+D E + N+ A+D G P+++ + V + +VND PP +F Q +Y + V+ + D + ++ + + Y + +++ T ++ + DRE + + +V + G L T K+ V++ D+NDN PVF +Y+ + EN E + ATD D G NGTV Y ++ D F ++ TG V T + LD E+ ++++A D G S + + V D D P YSF ++EN GT VG V+ + D + N + ++ G G+ F+I+ G+I+T +DRE + ++A++ E SV+V + D N+++P+ D+ EVS + P N F D D G+N +V+ + + F + PD
Sbjct: 291 VLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDL---GWFSVDESTGLVTTD--GKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPP--LFTQ------TKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSL-----TGKVTTLKSLDRE-ELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILEN---EPGGTAVTTVTATDPDRGANGTVRYQLT--AGDAAR-FQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANVTYL------IVSGDQRGS-------FSIEWSGGRIFTANAIDREEQAFYQLRVVANSGGV-------------AGEASVSVLVHDVNNHAPVF---DRASY-----EVSIAEDE------PVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFPD 811 HSP 7 Score: 127.102 bits (318), Expect = 1.168e-29 Identity = 151/607 (24.88%), Postives = 246/607 (40.53%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKE-----SEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGV--ALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDT--EGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISN-------VVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLK 2204
NDN P F E+ EN+ I A DAD + +Y + +E V VD +L ++DRE T+ A DG ++ + V D ND P+FS+ Y + E + T + + D DSG G+++ A S + D + + LH V AL + LD E+ Y A D G ++TA + V V + ND+ P++ N ++ + + E + + TDDD + + E+E F +++ ++ DRE ++ + + + SD +L ++ +I+ D+NDNAP F+SPR +++ V +V + A D D G N VEY ++ F+++ TG V+ + LD E + ++ + A D G P +S+ L V V D NDN P Y + E+EP GT V +++ D D N + + + P F +D G + LDRE ++ A+ A + G R DT + VT++ D ND SP L
Sbjct: 1510 NDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFV---------VDAASGVLRASRRLDREERASYLLTVRASDG---THATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADG---AFGLHPVTGALNVTRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQ----NDSLAAE-----VPEDAPPGTSLLRISATDDD---EGVNAELE-----FSISSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVAT----VQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYD----------IASGDPTGD-FRLDPVLGTLAVARPLDRERTASYELAVRARD------GGGPARS--DTASVRVTLS--DVNDCSPAFQLS 2057 HSP 8 Score: 127.102 bits (318), Expect = 1.178e-29 Identity = 130/489 (26.58%), Postives = 203/489 (41.51%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSR-----ISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPI---LIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQ--PPRSSTAL-VEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR--VNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYEN 1853
NDNSP F Y ++ E++ + + I +A DAD PFG +Y + P+E+ D D P+ L V +DRE A DGG ++ + VLD ND P ++ E G LL + D D G N ++ + +S D + F + L + LD E + Y+ + D + P R S+A+ V + +T+VND+ P F P S E + V+ V+ D D+ +S + + T E A N T E++ + DRE + + ++++ D +G L T L V + D NDNAP F Y + E+ E++ ++ A D DEG NG + Y I++ D F +D G + LD E+ + + A+D G P RS + + V + D ND P LS Y+ EN
Sbjct: 1611 NDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYAL-APSEDSD------WADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSG---DPEGRFAVGNDGQ---LSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAP-----AFTSPRSA-----LAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVD-KGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLS-----AWDPDEGANGELRYDIAS--GDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHAREN 2066 HSP 9 Score: 94.3597 bits (233), Expect = 1.128e-19 Identity = 63/197 (31.98%), Postives = 88/197 (44.67%), Query Frame = 3
Query: 657 HQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS 1247
++DRE T++AVD G+PP + + V D ND P+F + YE I E E G E+L L D D G NG++ + AS D F+L L L + LD E Y + A+D G P RS TA V V +++VND P + ++ E T V+ L V DD+ S
Sbjct: 1905 RELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASG---DPTGDFRLDPVLG--TLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYT---------VHARENTQGPPVLILQVVARDDDLGSS 2087 HSP 10 Score: 92.0485 bits (227), Expect = 4.963e-19 Identity = 112/448 (25.00%), Postives = 180/448 (40.18%), Query Frame = 3
Query: 1035 AKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINK--DPILATDKDEGENGTVEYYI--SNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNN 2363
A F +PP SS VE+ V +VND+PP + + + E T + VI + TD D Q +T + + E ++ + + +R+ DRE + + +++ SD +L V ++D NDN+P FS Y V E+ + T +LA D D G G V Y + S D F + TG + LD E + A D G +++ +L VNV D NDN P V + E+ E+ P GT + +++ TD D +N + ++ + P + F + N+ G++ LDRE S + S+ + R + + V++ + D NDN+P P+ A+ PE S P V VD D G NS V + +
Sbjct: 1488 AGSFIRPPMSSFNQVEISVEDVNDNPPVFAVPEME---------LEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRR---------LDREERASYLLTVRASD----GTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGG--GLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEF----------SISSGDPEGR-FAVGND-GQLSVARALDRERQSFYNLVVRVSD-------RARHPPARLSSAVRVSLILTDVNDNAPAFT---SPR-SALAPEDS-----------PVGAVVATVQAVDPDSGRNSYVEYALATD 1877 HSP 11 Score: 54.6842 bits (130), Expect = 1.366e-7 Identity = 41/153 (26.80%), Postives = 69/153 (45.10%), Query Frame = 3
Query: 1440 KLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL--ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILG------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYV 1874
++ V++ D+NDNAP F P V E E + + +L A D+D G NG V ++ +V + + + L LD E ++ + A+D G P R +++ V V+D NDN P + Y + E+ P+G +
Sbjct: 8 EVRVVVGDVNDNAPSFPEPG----VMEVAFKEDAAVGRQVLLDTAVDRDVGPNG-VNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAAL 155
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: si:ch211-199f5.1 (protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]) HSP 1 Score: 176.407 bits (446), Expect = 1.558e-45 Identity = 150/541 (27.73%), Postives = 254/541 (46.95%), Query Frame = 3
Query: 234 DSFQLIN-----GRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVD------DMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEV 1817
D F L++ G V+ R IDRE+ C ++ + C L G+ + V+ +++++DIND++P F + EI E+ + +R+ L A D D + +Y +++ NE F + + T+ K L+VK ++DRE L A DGG PPR G T + + VLD ND P F+Q + ++E G LL L D D G NG++ +F+S + +++ FQL ++LK +LD+E ++Y ++ A+D G + V V V ++ND+ P I + + + + ++++EG + + LV V+D D+ + + C + F L L R Y + + DRE +F+ + SD G + V + D NDN P F Y +++ N VT + A D D NG + Y NVV+ + Y SI+ ++G + + LDYE + ++ ++ A+D GVP ++ + V + D NDN P V
Sbjct: 70 DDFSLVHVEEADGTVSAREVIDREQQCGQAPSCVIRFDVLCT-----LPRGL------FQLVHAEVELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHLDE-NERFGLALRARTDGA---KYAELVVKSRLDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLK--GQLDHELNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEI---KLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLR-GHPHFKL--------LPYRDDYVVVTNSSLDREQMADYFLVLEASDG-GTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTT----VTAWDADAEHNGMIAY---NVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVV 573 HSP 2 Score: 110.538 bits (275), Expect = 7.929e-25 Identity = 131/503 (26.04%), Postives = 211/503 (41.95%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVA---LKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-----NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAP------VFSSPRYYGIVKENRVNE----IVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSID--KNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN--PLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
+++LD ND P F++ ++I ES G + D D G N + + +++ + L G L + S+LD E +Y+ L A D G PPRS T LV + V + ND+ P VF Q + + + E T V+ + TD D + E Y + +A + + KT ++ K D E + + +SI D G + + K+ V ++DINDNAP + S V E E +VT+ +D D ENG V ++ +F + ++ VV T LD E++ + + A D G P R ++ + V + D NDN+P S Y L EN G YV V D D + N +++ + G ++ T +I+ SG IY LD E + + F + A + PL +V+V I+D+NDN+P++
Sbjct: 124 VELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHL----DENERFGLALRARTDGAKYAELVVKSRLDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSP--VFAQTS-------CNVTVREDATPGTVLLTLNATDVDEGPNG---------EVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDHELNSEYEISIQARDM-GPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTV-------SDIDSAENGLVACHLRG-----HPHFKLLPYRDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVST------YVSINPSSGAIYALRPLDYEAMTSLTFQVQARDDGVPPL------------VTNATVSVRIVDENDNAPVV 573 HSP 3 Score: 72.0182 bits (175), Expect = 5.662e-13 Identity = 115/490 (23.47%), Postives = 196/490 (40.00%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF-----------SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITC------EIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYY---GIVKENR---VNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVV----KTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVD 1820
NDNSP F + + + E++ + + A D D+ P G Y P D + + + +D K L +K Q+D E E ++ A D G K+++ V D ND P+ + + E ES GL + V D DS NG ++ + + F+L + S LD E + Y L A D G PPR + V + + ND+ P F++ S + E + + V D D + + + E+ + S Y++ ++ + Y ++ +D++ T +L F V + +G+ L + V I D NDNAPV + P G+V+ R + +VT+ + A D D NG + Y I V + +N F I++ G V ++ +H S+ + +D G P S++ + + V D D
Sbjct: 239 NDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSP---VDAEVRRLFQ--LDPKTGKLSLKGQLDHELNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYES-FVGL----VTVSDIDSAENGLVACHLRGHPH------FKLLPYRDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPR--FHRSTYEAS-------LLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAI-----YALR-PLDYEAMT-SLTFQ--VQARDDGVPPLVTNATVSVRIVDENDNAPVVTHPPLRNGTGVVRLPRDAGLGYLVTV----VRARDSDSEANGELSYRI--VQGNERNLFRINRLGGEVFTNAASVTDAAASATRH-SLVVMVRDRGSPALSATAAIEIRVGAHGDGDDGAD 687 HSP 4 Score: 68.9366 bits (167), Expect = 5.365e-12 Identity = 94/386 (24.35%), Postives = 159/386 (41.19%), Query Frame = 3
Query: 1392 IVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPI-LATDKDEGENGTVEYYIS---------NVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGP----TLGTSQPAD----QIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV------DLDEGENSKVRVTMKNNDYFSLTP---DYGMLC--AMEKLPPIGDYKTVIVAEDG 2462
++C+ G+ QL EV + DIND+AP F+ + + E+ + + P+ A D D G N Y++ D Y + VVK+ LD E+ +++++A D G P RS + + + V D+NDN P + + + E+ GT + +N TD D GP S P D ++F +D ++GK+ K LD E++S+ +I A + P V V++ D NDN+P + L FI S + ++ + FV D+D EN V ++ + +F L P DY ++ ++++ + DY V+ A DG
Sbjct: 108 VLCTLPRGLFQLVHA---EVELLDINDHAPDFARSEMHVEISES----VALGTRVPLEGARDLDVGGNALRAYHLDENERFGLALRARTDGAKYAEL-----VVKSR--LDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDE----------------GPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDHELNSEYEISIQARDMGPSSI----------PAHCKVLVHVEDINDNAPEIKLD-------------FIMQSRGDTVFVSEGAAYES-FVGLVTVSDIDSAENGLVACHLRGHPHFKLLPYRDDYVVVTNSSLDR-EQMADYFLVLEASDG 438
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 172.555 bits (436), Expect = 3.393e-44 Identity = 188/735 (25.58%), Postives = 306/735 (41.63%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVD------------------NKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQ-LIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASS-TNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQY---ARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLE--NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPR--------YYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVV--DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPE-VDLS-----FYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDK----PQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND---YFSLTPDYGMLCAMEKLPPI--GDYKTVIVAEDGDFNNSRK 2483
ND++P F I E+ + R+ LP A D D ++ Y I + + +L V+ + +L ++ Q+DRE + E L DGG P G + + V+D ND P F ++I E G ++ LR D D+G NG I+ +F + T+ Q + T V ++ KLD ET+ + +VA+D GQ RS++ V V + + ND+ P VF + +Y + I E + L+ V+D D + ++ +E T A L N+ + +K+ D E + VS++ +D G +L + L + + DINDN PVF +P Y ++EN V +N +LATD D G NG + + +S + + + FS++ TG + LD EK + + A D G P R + + V V D NDN P V +S Y F + E +GTYVG V+ +D D N + + ++ P G D G + T VVLDRE Q ++ A +D G+ + +S+TV+ D NDN+P++ + V+ +P + S N D+D G+N + + + F L D G L + + G ++ V+ D + SR+
Sbjct: 138 NDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGD---GLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAP--VFEVIA--LQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLE----------FPTGAELASPNKVQFLLKTTRLLDYEEAQQYNVSVLAAD-RGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLN---LLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAG---------DTPGGVVRTLVVLDREDRVQYELSVRA-----VDSGRP---ALSASCRVSITVS--DTNDNAPVITSPNTNDTWKHVRTFSPAGMLVGVSVTAN--------------DIDAGDNGRPLYEIIGGNPKGIFLLNADSGALSLARTVSSLDEGLHRLVVRVRDRGGSGSRR 818 HSP 2 Score: 119.398 bits (298), Expect = 1.324e-27 Identity = 145/577 (25.13%), Postives = 238/577 (41.25%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQ-NTFQLSQTL-----------------HGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFY--LNALKTNAVLENRKT---YEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIK--DINDNAPVFSSPRYYGIVKENRVNEIV--TINKDPIL---ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQP--------EVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVS-----FIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM 2354
L V D ND P F + I ESE G + R D D+G N ++++ +Q F L ++ H L+L +LD E + Y L +D G P S + L+ + V + ND+ P F P ++ + I E + + ++ D D + SF+ L +L T A L T +++ DRET +H + +V D QL ++ + V ++ D NDNAPVF G + +IV + P++ +D D G +GTV+ + S +K ++KT LDYE+ + ++ + A D G P S + LI++V D NDN P E D++ Y L EN P GT V + TD D+ N + L + ++F+++ +G++ LDRE + ++ A + G R+ R V V +LD+NDN+P + V+ + F++ T+ Y T DLDEG+N++V + +
Sbjct: 132 LLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAP-----VFVDPPTRP---VRITEHSKVGTSVVQLRAADPDAGPNGAIA------YSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDG---GQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLE--FPTGAELASPNKVQFLLKTTRLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSE-------LAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACD------GGSPQRKARAI----VRVTVLDENDNAPTFV--------GVSNSTNCMYQFFVEEETSVGTYVGTVSTS-----DLDEGDNARVALNL 659 HSP 3 Score: 58.9214 bits (141), Expect = 5.795e-9 Identity = 75/306 (24.51%), Postives = 121/306 (39.54%), Query Frame = 3
Query: 1353 DFDRETKTLHFVSIVC-SDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNY--FSIDKNT-------------------GVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPE-VDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVV--LDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPM 2192
D R T +H V + + +G + L+ + ++++++DIND+AP F +P I + V V + + A D D G N Y IS D FS+ ++ +++ LD E + + + +D G P S SV L + V D NDN P VD + E+ +GT V ++ D D N L TS +D +G + + LDRE ++A D G Q + ++VTV + D NDN+P+
Sbjct: 100 DACRSTGFMHTVQVAAMAKGQGSSNLRLLD-VQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPR----AIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKL-------TSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVAR-----DGG-----QLSRSASVTVTVELNDDNDNAPV 383
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009557.1 (pep scaffold:Pmarinus_7.0:GL476748:59426:101420:1 gene:ENSPMAG00000008644.1 transcript:ENSPMAT00000009557.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 147.902 bits (372), Expect = 3.745e-36 Identity = 166/667 (24.89%), Postives = 281/667 (42.13%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADD---LPFG-VESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETS--QESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD--PIL--ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSS--VKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMK-NNDYFSLTPDYG 2393
N++ P F Y + E + N+ I A D DD L F V S ++ + FKL D L +D E T++ D P +K +++ V D ND P F+ YE ++ ES G +L + D+D G N +++ + + N+++ N+F + T+ G+ L + +LD + Y + A D G+PPRS+T V V VT +++PP K SK Y+ ++EG + +V + ++ EI +++FY+N T+ V+ ++ + + K + + + + V L + + + D NDNAPVF +Y G+V E + V +N P++ ATD D +N + Y I V + + YFSID +TG +K I LDYEK ++ D G P S+ + + V D ND+ P + Y L G + ++ TD DTD + ++ T D+ F I+ +G I + + S+ A+ K +F T + V V + D NDN+P+ + + P V + + V + D D G N +V ++K ++YF + G
Sbjct: 10 NEHRPQFSRPRYEVSVAEETPPNTEILRLNATDRDDTSSLTFSIVSSTDVASLRK-----FKL------DYNTGALSTVESLDHETKQSHILTVMVRDSEIPVQKAYATVVVNVRDSNDHAPLFTSRHYEGRVVESAALGSAVLEVVALDRDRGPNAEVAYSIEAG-NRNVGNSFTIHPTM-GI-LSVAKELDRAVVEAYELVVRAVDRGEPPRSATTAVRVLVTVADNAPP--------KFTSKDYS-AEVSEGARPGSFVLMVTAS----SRSTVNYEIRDGNFEDTFYVN--PTSGVITTKELLDYERKPSYQLKIQATNMVG-----------LSTNASVSIHLSDENDNAPVFDRSQYRGVVSEEAQAQTVVLNDKNVPLVIRATDLDSEQNSLLVYQI--VEHEAQTYFSIDSSTGAIKMIKVLDYEKTPEFHFQVRVSDSGSPKLSAETPANVTITVLDANDSPPIFSRAVYETVLLTPTYSGVRLLSMSATDPDTDASLTF------------SISTGNVGDK-FAINARTGDISVQNAT--HLRSRYELAV-----------KVFDGKFVSTAQAVVAVRVEDVNDNAPVFV--NLPYYAVVEVDAA------------PGSVVYTIAAFDRDVGRNGEVSYSLKEEHEYFDVEARSG 594 HSP 2 Score: 130.954 bits (328), Expect = 5.881e-31 Identity = 154/642 (23.99%), Postives = 272/642 (42.37%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKII-LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSG-NNGKISINFASS---TNQDI-----QNTFQLSQTLHGVALKLISKL-----DYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQES--FYLNALKTNAVLENR---------------------KTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI-VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPE 2237
NDN P F Y ++EN + A D D G +Y + + + + VD + + +DRE E ++A D G P R T + + V D NDC P+F + Y + E G + + +D D+ +NG+++ + +D ++ + S+T+ ++++L++ L + E+ +++ + D G+PP +TA V V V++ ND+ P V + K AR E + +C V D D+ A++ ++ I+ E+ F+++ + V+ R +++ K DRE + + + + +D +++ ++V + D NDN+PV Y + V E+ I + + A D D G N ++Y + +F +D TG + T+ LD E + ++ + A D G RS +++V+++D NDN P+ S Y+ +YE+ + T + +V TD D +N K T A F ID SG I K LDRE + + A + D+FR T+ +SV V LD NDN P ++ + A PE
Sbjct: 1266 NDNRPVFESSVYEGVVMENLPAGVPVVQVRATDRDGGANGQLAYSLAEEAGGEGGAARDLFS--VDAESGWVRTLRPLDREARAGHELAVVATDLGDPARLSATASVRVAVADANDCPPRFLRGSYAGDVPEDSAPGQVVAVVGADDADATPDNGQLTYYLTGAPRVAAEDALPGHGEHVLRESRTV-AISVELLTILPPTVRETESACQFNIGVSIVDGGEPPLQTTARVVVRVSDENDNAPQFVEKRVQV---KALAR----ERSVAREAVCRVYARDADHGANAELSYSIDGGNEAGKFFID--PKDGVISTRNPCPVGTNDFLTVPCDIYVVVGEWKLHLKQPVDREERDRYQIEVTATDGAFVSKAV----VDVAVLDANDNSPVCDKGLLYAVAVAEDVAPGIFLL---LVSARDADIGANAAIQYTLHG---PGAEHFRMDSATGELFTLAPLDREAVPAYALSVRATDGGG--RSCQAEILVSLEDVNDNAPQFPASHYAVSVYESTAVETLLTRVQATDSDLGLNRKV------------TYSFLDSAGGHFAIDERSGIISLKRPLDREHQAVYELTVRAED-------GDVFRPLTSTVGVSVAV--LDVNDNPPAF---EQREYHAAAPE 1859 HSP 3 Score: 101.679 bits (252), Expect = 5.967e-22 Identity = 168/735 (22.86%), Postives = 276/735 (37.55%), Query Frame = 3
Query: 444 PTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVL------DENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQL-SQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPR-SSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNA-----------VLENRKTYEIKSKI-----DFDRETKTLHFVSIVCSDTEGIN-QLKQTNKLEVIIKDINDNAPVFSSPRYY--GIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKT--------------------ILG---------LDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLS-FYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM--KNNDYFSLTPDYGMLCAMEKL--PPIGDYKTVIVAEDGD 2465
P F E Y + E++++ S I + D + N D + L ++ L V +D E + F + A R+ + ++ +VL D ND P F +YE + E+ G+ ++ +R D+D G NG+++ + A + L S ++ + LD E + +VA D G P R S+TA V V V + ND PP + + + E + V+ +V D D D+ Q ++YL A VL +T I ++ RET++ +I S +G L+ T ++ V + D NDNAP F R + +E V + A D D G N + Y I + F ID GV+ T ++G +D E+ IE++A D G V + V V V D NDN P D Y+ + E+ G ++ V+ D D N L G P + F +D+ +G+++T LDRE ++ A++ G+ + + + V++ D NDN+ PQ A + VS +++ E + T D D G N KV + +F++ G++ L Y+ + AEDGD
Sbjct: 1163 PAFTEAAYALTVAEDAEVGSEIGVARLAGNDSATYAAVPGGGGAENNADDTFVVL-------SQTGRLKVAKALDHETVRSYRFGVKATF-----RRDEVDVVAQVLVTVHVGDVNDNRPVFESSVYEGVVMENLPAGVPVVQVRATDRDGGANGQLAYSLAEEAGGEGGAARDLFSVDAESGWVRTLRPLDREARAGHELAVVATDLGDPARLSATASVRVAVADANDCPPRFLRGSYAGDVP---------EDSAPGQVVAVVGADDADATPDN-------GQLTYYLTGAPRVAAEDALPGHGEHVLRESRTVAISVELLTILPPTVRETESACQFNIGVSIVDGGEPPLQTTARVVVRVSDENDNAPQFVEKRVQVKALARERSVAREAVCR---VYARDADHGANAELSYSIDG--GNEAGKFFIDPKDGVISTRNPCPVGTNDFLTVPCDIYVVVGEWKLHLKQPVDREERDRYQIEVTATD-GAFVSKAVVD--VAVLDANDNSPVCDKGLLYAVAVAEDVAPGIFLLLVSARDADIGANAAIQYT-----LHG-------PGAEHFRMDSATGELFTLAPLDREAVPAYALSVRATDGG----GR--------SCQAEILVSLEDVNDNA--------PQFPASHYAVSVYESTAVETLLTRVQAT------DSDLGLNRKVTYSFLDSAGGHFAIDERSGIISLKRPLDREHQAVYELTVRAEDGD 1823 HSP 4 Score: 96.2857 bits (238), Expect = 2.774e-20 Identity = 103/410 (25.12%), Postives = 178/410 (43.41%), Query Frame = 3
Query: 684 RIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPP--NIVFYQFNKPIS-KQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDT 1904
R E + DG K + + ++V D ND P F L Y ++ G + + D+D G NG++S + ++ F + V+L+ D + ++ N+VA D G PP SS V + +T +N + P FY + P + K + I + + + + + +TD D +Q S N N + D ET+T +++ +D+ + L+++++D+NDN P+FS Y + E ++ I+ + ATD D G N + Y I N + F ID ++G++ T LDYE+ + + + A D G+P +S V + + V D NDN P + Y + E P G +V +V +D D
Sbjct: 507 RYELAVKVFDG-KFVSTAQAVVAVRVEDVNDNAPVFVNLPYYAVVEVDAAPGSVVYTIAAFDRDVGRNGEVSYSL-----KEEHEYFDVEARSGDVSLRRSFTADMSS-KDFTVNVVATDSGVPPLSSE--VSLPITVINKAMPIFERPFYSKSVPENIKPHTPILNLQAKSPEGLPLIFSITDGD----------PFNQFSIDFNTGVVNVIGS------------LDHETQTTFKLTVRATDS--VTGSHAEVNLDILVQDVNDNPPLFSQSAYATTLSEA---ALIGISVLQVSATDADIGSNKALYYQIINNGKNSSECFYIDSSSGLILTSRFLDYEQNQVHNFLVRASDSGMPFLTSDVPVTITVTDINDNPPVFNQLLYEAFVSELAPRGHFVTRVQASDADA 880 HSP 5 Score: 93.2041 bits (230), Expect = 2.469e-19 Identity = 104/418 (24.88%), Postives = 167/418 (39.95%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAY--DADDLPFGVESYEIEKPNENFDVYF-------------KLMTEDFVDNKQPILIV--------KHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQ-LIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYI 1613
NDN+P F EK + L + +R ++ Y DAD SY I+ NE + + T DF+ I +V K +DRE DR + + A DG K + + VLD ND P + L+Y + + E G+ LL + D D G N I + + + L ++ LD E + Y+ ++ A D G RS A + V + +VND+ P QF P S +Y E T + ++ V+ TD D + +L++ + ++ R I K DRE + ++ +++ D + L T + V + D+NDN P F Y+ E+ ++ +LA KD G N V Y +
Sbjct: 1501 NDNAPQFVEKRVQVKALARERSVAREAVCRVYARDADHGANAELSYSIDGGNEAGKFFIDPKDGVISTRNPCPVGTNDFLTVPCDIYVVVGEWKLHLKQPVDREERDRYQIEVTATDGAF---VSKAVVDVAVLDANDNSPVCDKGLLYAVAVAEDVAPGIFLLLVSARDADIGANAAIQYTLHGPGAEHFRMDSATGE------LFTLAPLDREAVPAYALSVRATDGGG--RSCQAEILVSLEDVNDNAP-----QF--PASHYAVSVY--ESTAVETLLTRVQATDSD-------LGLNRKVTYSFLDSAGGHFAIDERSGI-ISLKRPLDREHQAVYELTVRAEDGDVFRPLTSTVGVSVAVLDVNDNPPAFEQREYHAAAPEDAAPGSAVLS---VLAISKDAGANAEVTYSV 1887 HSP 6 Score: 91.6633 bits (226), Expect = 7.239e-19 Identity = 135/594 (22.73%), Postives = 232/594 (39.06%), Query Frame = 3
Query: 252 NGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLP--FGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQID------REFIDRIEFTLIA--VDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKI--KESEMTGLELLHLRVEDKDSGNNGKISINFASS------------------------TNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQ---YARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVII--KDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGV--PVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDT 1904
+G V RP+DRE H+ + + G L +++ V D ND P F +Y ++ E+S +++ A DAD P + Y P + E + + + I + RE +F + VDGG+PP + +++++V DEND PQF + ++K +E + + + D D G N ++S + TN + + + L L +D E ++Y + A D S A+V+V V + ND N P+ + YA + + E + + LV D D A++ + L+ + T E+ + DRE + +S+ +D G ++ + E+++ +D+NDNAP F + Y V E+ E + + ATD D G N V Y + +D +F+ID+ +G++ LD E + + A+D V P+ +S+V + V V D NDN P + Y E+ G+ V V KD
Sbjct: 1332 SGWVRTLRPLDREARAG----HELAVVATDLGDPARL----------SATASVRVAVADANDCPPRFLRGSYAGDVPEDSAPGQVVAVVGADDADATPDNGQLTYYLTGAPRVAAEDALPGHGEHVLRESRTVAISVELLTILPPTVRETESACQFNIGVSIVDGGEPPLQTTARVVVRVSDENDNAPQFVEKRVQVKALARERSVAREAVCRVYARDADHGANAELSYSIDGGNEAGKFFIDPKDGVISTRNPCPVGTNDFLTVPCDIYVVVGEWKLHLKQPVDREERDRYQIEVTATDGA---FVSKAVVDVAVLDAND----------NSPVCDKGLLYA-VAVAEDVAPGIFLLLVSARDADIGANAAI--------QYTLHGPGAEHFRMDSATGELFTLAPLDREAVPAYALSVRATDGGG-----RSCQAEILVSLEDVNDNAPQFPASHYAVSVYESTAVETLLTR---VQATDSDLGLNRKVTY---SFLDSAGGHFAIDERSGIISLKRPLDREHQAVYELTVRAEDGDVFRPL-TSTVGVSVAVLDVNDNPPAFEQREYHAAAPEDAAPGSAVLSVLAISKDA 1877 HSP 7 Score: 87.8113 bits (216), Expect = 1.184e-17 Identity = 140/554 (25.27%), Postives = 237/554 (42.78%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFT--LIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQAD-----SITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKE-NRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIK-HVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLG------TSQPADQIFTIDNESGKIYTKVVLDRE 2048
NDN+P F YY + ++ S + A+D D G SY +++ +E FD V+ + + ++ + + +FT ++A D G PP + + + V+ N P F + Y + E+ +L+L+ + + + + F S T+ D N F + + + +I LD+ET + + A D + L ++ V +VND+PP +F Q YA ++E + + V TD D ++ I + S E FY+++ + +L +R D E +H + SD+ G+ L + + + DINDN PVF+ Y V E VT + A+D D + +EY I + D M F +D +G++ +I L + + + IS D V +S+ ++ VN++ N + P + Y E+ EN +GT + V TDKD GP LG +Q A FTID E+G+I+T LDRE
Sbjct: 535 NDNAPVFVNLPYYAVVEVDAAPGSVVYTIAAFDRDVGRNGEVSYSLKEEHEYFD----------VEARSGDVSLRRSFTADMSSK-DFTVNVVATDSGVPPLSSEVSLPITVI--NKAMPIFERPFYSKSVPENIKPHTPILNLQAKSPEG-----LPLIF-SITDGDPFNQFSID--FNTGVVNVIGSLDHETQTTFKLTVRATDSVTGSHAEVNL-DILVQDVNDNPP--LFSQ------SAYATT-LSEAALIGISVLQVSATDADIGSNKALYYQIINNGKNSSECFYIDS-SSGLILTSRF---------LDYEQNQVHNFLVRASDS-GMPFLTSDVPVTITVTDINDNPPVFNQLLYEAFVSELAPRGHFVT----RVQASDADASDTDKLEYSILSGNDHMN--FVVDGKSGII-SISNLRKQTLAPQYRLNISVSD---GVFTSTAQVHVNIQSANLHSPIFGQNEYVKEIPENSEVGTLLTLVQATDKDW----------------GP-LGHVSYSIVNQFAGDRFTID-ENGQIFTSEPLDRE 1018 HSP 8 Score: 81.6481 bits (200), Expect = 8.951e-16 Identity = 139/605 (22.98%), Postives = 249/605 (41.16%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHG-VALKLISKLDYETIN-KYSFNLVAKD--FGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEI--ETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYG--IVKENRVNEIVTINKDPILATDKDEGENGTVEYYI----SNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRD----TMEISVTVNILDKNDNSPMM 2195
NDN P F + Y + E + I + A DAD Y+I +N F ++D+ +++ +D E F + A D G P + + V D ND P F+QL+YE + E G + ++ D D+ + K+ + S + ++ + G + IS L +T+ +Y N+ D F +STA V V + + N P +F Q +Y + I E + ++ LV+ TD D ++ I + + + F ++ EN + + + DRE I +G ++ T ++VI D NDN P F + Y+G + + + I+ +LATD DEG N + Y + S+ V+D+ + + ++++GL+ ++ S + A+D G + S V + V+V + P + Y+ + E+ +G+ +G + D+ +PG G AD F + +++G++ LD E F + A+ FR RD ++ VTV++ D NDN P+
Sbjct: 738 NDNPPLFSQSAYATTLSEAALIGISVLQVSATDADIGSNKALYYQIINNGKNSSECF------YIDSSSGLILTSRFLDYEQNQVHNFLVRASDSGMPFLTSDVPVTITVTDINDNPPVFNQLLYEAFVSELAPRGHFVTRVQASDADASDTDKLEYSILSGNDH-------MNFVVDGKSGIISISNLRKQTLAPQYRLNISVSDGVF-----TSTAQVHVNIQSANLHSP--IFGQ------NEYVK-EIPENSEVGTLLTLVQATDKDWGPLGHVSYSIVNQFAGDRFTID--------ENGQIFTSEP---LDREDPLERVFDINIMAKDGGGRVGFTT-VKVIATDENDNKPTFVTNEYFGNVLARAEKGTAILQ-----VLATDPDEGSNADLVYTLYKGESDAVEDVLEVQPLTGHVVTKESLVGLEGSRM---SFFVKAEDKGPERKHSVVPVSVSVLPADAELPAFTEAAYALTVAEDAEVGSEIGVARLAGNDS---------ATYAAVPGGG-GAENNADDTFVVLSQTGRLKVAKALDHETVRSYRFGVKAT-----------FR--RDEVDVVAQVLVTVHVGDVNDNRPVF 1272 HSP 9 Score: 73.9442 bits (180), Expect = 1.771e-13 Identity = 111/493 (22.52%), Postives = 208/493 (42.19%), Query Frame = 3
Query: 744 KIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQE----SFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDL-GVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYV---GKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
++ + V++ N+ PQFS+ YE+ + E E+L L D+D + S+ F+ ++ D+ + + + AL + LD+ET + ++ +D P + + A V V V + ND P +F S+ Y + V+ +V + D + IE SF ++ T +L K + DR + + + D G T + V++ ++ P F+S Y V E R V + + A+ + TV Y I + + ++ F ++ +GV+ T LDYE+ ++I A ++ G+ S++ + +++ D NDN P D S Y + E T V V + + TD+++++ + + ++ A F+ID+ +G I VLD E + + F + S D G + +VT+ +LD ND+ P+
Sbjct: 1 QVEVSVINTNEHRPQFSRPRYEVSVAEETPPNTEILRLNATDRDDTS----SLTFSIVSSTDVASLRKFKLDYNTGALSTVESLDHETKQSHILTVMVRDSEIPVQKAYATVVVNVRDSNDHAP--LF------TSRHYEGRVVESAALGSAVLEVVALDRDRGPNAEVAYSIEAGNRNVGNSFTIH--PTMGILSVAK--------ELDRAVVEAYELVVRAVD-RGEPPRSATTAVRVLVTVADNAPPKFTSKDYSAEVSEGARPGSFVLM----VTASSRS-----TVNYEIRD--GNFEDTFYVNPTSGVITTKELLDYERKPSYQLKIQATNMVGL---STNASVSIHLSDENDNAPVFDRSQYRGVVSEEAQAQTVVLNDKNVPLVIRATDLDSEQNSLLVYQIV-------EHEAQTYFSIDSSTGAIKMIKVLDYEKTPEFHFQVRVS-----DSGSP---KLSAETPANVTITVLDANDSPPIF 441 HSP 10 Score: 55.0694 bits (131), Expect = 1.002e-7 Identity = 50/215 (23.26%), Postives = 87/215 (40.47%), Query Frame = 3
Query: 276 PIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGK-PPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASS 917
P+DRE + + + + GG+ C + S ++ NDN+P FP Y + E++ + + ++ A D+D G+ ++ +F +D + I+ +K +DRE E T+ A DG P + + VLD ND P F Q Y E G +L + KD+G N +++ + S
Sbjct: 1702 PLDREAVPA----YALSVRATDGGGRSCQAEILVSLEDV-------------NDNAPQFPASHYAVSVYESTAVETLLTRVQATDSD---LGLNRKVTYSFLDSAGGHFA------IDERSGIISLKRPLDREHQAVYELTVRAEDGDVFRPLTSTVGVSVAVLDVNDNPPAFEQREYHAAAPEDAAPGSAVLSVLAISKDAGANAEVTYSVVSG 1890
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 201.83 bits (512), Expect = 1.320e-52 Identity = 187/672 (27.83%), Postives = 297/672 (44.20%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF----VDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIY-INEGTTKDMVICLVKVTDDD--NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAII---ASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKL 2417
NDN+P F +Y K + EN I ++ A D D+ EN V ++L D V+ ++ K +DRE + A+D GKP + I L + D ND PQFSQ Y + + E+ G +L + D D+G NG+++ + S + N F++ T + ++ +D E + Y+ + AKD G PP STA V + V + ND N PI Y I+EG + + +V TD D + A + +F +NA+ N VL +K + +RET + ++I SD G + +L V++ D+NDN PVF+S Y G V+EN + + A D D G N + Y I + D+ + F I+ +GV+ T LD+E+ +E++A D +++ ++N+ ND P Y+ + EN P T V KV+ +D+D+ +++ G + +D+ F+ID SG I T VLDRE+ S + A NP PL + VT+ ILD+NDNSP + S +S EN P + +F D DEG N+++ + ND F + G++ + L
Sbjct: 1093 NDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDE-------------GENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHG---NAFRIDSTTG--RITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADEND----------NSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAM--NGVLTVKK--------EINRETVPTYTLTIRASD-RGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLT---VAADDSDVGANAVLRYSIISGNDEKR--FKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINL---NDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDS------FGSLSYSIVGG------KDSDK-FSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNP-PL------------SNLTWVTIKILDENDNSPKF-------------DSSSYSSSILENSAP-SSFSFKLAATDADEGTNARITYNLSRNDAFMIGASSGVITLAQPL 1677 HSP 2 Score: 188.348 bits (477), Expect = 2.133e-48 Identity = 187/650 (28.77%), Postives = 289/650 (44.46%), Query Frame = 3
Query: 255 GRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFA--SSTNQDIQNT-FQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPM 2192
G +T R P+DRE S + IN+ G F+ + + I + D NDN PTF + + I E+S +R+ A D D P G +Y I N+ F+L D + IL V+ +DRE I + A D G P + I + VLD ND P+F + ++ +I+E +L ++VEDKD G+NG I+++ + S N I +T F LS+T LDYET Y + A+D G P +S+TA V++ + NVND+ P+ V I + A IN +VK+ D+ +T +I +++ ++ K DRET T ++ +V + G N + + D+NDNAPVF+ Y + EN + + V + ATD+DEGEN V Y +S V D K F ++ TG+V T LD E S+ ++A D G P +S+ + + + D NDN P+ S Y+ + EN G+ + +V +D D N + I S F ID+ +G+I V+DRE + I A + + F V + + D+NDNSP+
Sbjct: 740 GEITTRVPLDRETIAS----YSLTINAD--DGSLVRFMAATT---------VNISIADENDNQPTFTGPSRFN-ISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNS--FQL------DPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTIDSTGFVLSKT----------PLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVA---IN--------THVVKLNATDSDGTPLTFDIVEGNAGSSFKIDQSSGLISVAKR--------LDRET-TANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVA----KVTATDRDEGENAKVTYELS-VGDTSK--FEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSII-----------SGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAF----------VAITVADENDNSPI 1307 HSP 3 Score: 159.458 bits (402), Expect = 1.900e-39 Identity = 180/704 (25.57%), Postives = 288/704 (40.91%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED---FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVF----YQF----NKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV--NEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKLP------------PIGDYKTVIVAEDGDF 2468
NDN+P F Y + E+ + S + A D D G+ N + + L++ D F + Q ++ K DRE + L A DGG P R G+ + +++LD ND P FS Y + E G ++ + DKD+GNN + +F T+ + + F L + GV + + LD+E + Y+ L D G PP + T+ + + V ++ND+PP VF YQ N P Q + + T +V ++K DD F ++ + YE K++ D V + G+ T ++ + I+D+ND++PVFS Y + E+ V + +VT+ ATD D G G +EY + + ++K F+ID N+G ++ LD E S+++ A+D G RSSS ++ + ++D NDN P + Y F + E+ G +G+V TD D N N +F+I+ +G I K LD E +Q + A KD R ++ + V V + D NDN P S + EN+ V + D D G N K+ Y L+ + M AM++ I Y I A+DG
Sbjct: 162 NDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLD---VGI----------NARLSYSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSF---TSGNTNHAFTL-DAVTGV-VTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPP--VFSPSAYQSRVKENTPAGTQVSATDRDSSTNGALVFGIIKGNDDG---------------VFTIDGSTGIISIAKSPDYENKTRYDL-----------TVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVT-----ATDLDSGPRGRLEYRL--ISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSP-IFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNT-------------DVFSINTSTGLITLKTQLDYEKKTQYMVTVTA---------KDGGTPSRSSLTV-VKVMVDDVNDNPPQFAK-------------SLYTCTVGENLAAGVAVCY-VTATDADSGANGKIS-------YSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSL 767 HSP 4 Score: 146.362 bits (368), Expect = 2.184e-35 Identity = 181/684 (26.46%), Postives = 280/684 (40.94%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDE-NDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQAD---SITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNN-DYFSLTPDYGMLCAMEKL--PPIGDYKTVIVAEDG 2462
NDN+P FP +Y I EN+ +++++ A D D +Y + F K M + + + H+ + RI A DG K T + L +D+ ND P F+ +Y+ + E G + L D D G N ++S + S +T + GV ++ D ET Y L A+D G P RS A VE+ + +VND+ P Q+ + + A MV D+ N AD S T + +F L+A+ T V +R +DF E ++ + + + +D G L T+ L + + DINDN PVFS Y VKEN T + ATD+D NG + + I DD F+ID +TG++ DYE + + A+D GVPV+ + ++ + ++D ND+ P S YS ++ E+ IG+ V V TD D+ L+ G G F ID SG I LDRE + + A + + VT+ + D NDNSP+ P V V +E+ P + + D D+ N VR + +N D FS+ G++ +L Y + A+DG
Sbjct: 64 NDNAPEFPLNSYVFNIRENTPA-AQVAIVTATDRDSGTNAAITYSL------FSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRIS----AFDG-----KHTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSG------DTSYFTVDSQGV-IRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVA-------IGAAMVTVTASDKDNGNNADLRYSFTS--GNTNHAFTLDAV-TGVVTVSR-------SLDF--EQRSSYALGLSVTD-RGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKEN------TPAGTQVSATDRDSSTNGALVFGIIKGNDD--GVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDS----GPRGRLEYRLISGNVKGA-------FNIDANSGSIRVSSELDRETTPSYSLQVEARD----------GGSTSRSSSTRVTIALQDINDNSPIFQ---GPYVFRV-----------SESSSPGHQIG-QVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDG 660 HSP 5 Score: 141.739 bits (356), Expect = 5.216e-34 Identity = 142/518 (27.41%), Postives = 237/518 (45.75%), Query Frame = 3
Query: 642 ILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN-PLDYGKDLFRQFRDTMEISVTVNILDKNDNSPM 2192
I + DRE R T++A D KG+T +++ V DEND P+F Y I+E+ ++ + D+DSG N I+ + S N+ + N S+T ++ ++ LD+ET + Y+ + A D + +T + + V +VND+ P F+ + + Y + + +V L V D ++ + + S++ + + V I++K FDRETK + V++ D ++ Q +E+ I D+NDN PVFSS +Y V E+ + + A+DKD G N + Y ++ + + F++D TGVV LD+E+ ++ +S D G P + + L++NV D NDN P S Y + EN P GT +V+ TD+D+ L+ G G D +FTID +G I D E ++ + A + P+ Y DT + VT+ I D ND+SP+
Sbjct: 21 ITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIREN-TPAAQVAIVTATDRDSGTNAAITYSLFSGENKFMMN----SKTGE---IRTVTPLDHETKDSYTMRISAFD----GKHTTFVPLITVDDVNDNAP---FFALSVYKTGVYEDVAVGS-----IVRQLTAVDLDVGINARLSYSLVSGDTSYF--TVDSQGV--------IRTKGAFDRETKASYQVALRAQDGGSPSRSGQAT-VEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVT---VTASDKDNGNNADLRYSFTS--GNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDS--------STNGALVFGIIKGND---DGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKY---------DTAQ--VTIFIEDVNDHSPV 477 HSP 6 Score: 139.813 bits (351), Expect = 2.399e-33 Identity = 186/724 (25.69%), Postives = 305/724 (42.13%), Query Frame = 3
Query: 228 DTDSFQL--INGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSI---TCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIK--DINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
DT F++ G VT +RP+DRE+ S S + T ++ I + ND +NDNSP F + Y + EN+ S I +A D D G +Y I N F+ +D+ + V +DRE + T+ A D G PP + + V DEND P F+ I E G + + D+D G+N ++ F S D + F + ++GV L + +++ ET+ Y+ + A D G P +S + V V +VND+PP FN S+ Y + E + + + V D D A+++ + ++ F +N+ T+ V I + D E K+ + + + +D+ K T K V I+ ++ND P F+ Y V+EN + + A+D+D G++ Y I D K FSID+ +G++ T LD E + +I++ D G P S+ + + + D NDN P+ D S YS + EN ++ K+ TD D N + T S+ + F I SG I LDRE S AI A D+G I++ V ++D ND+ P++ S ++ S EN P+ + D D G N+++ ++ +N++ S+
Sbjct: 1142 DTSKFEVNPATGLVTTKRPLDREDQASYSLR-VTAMDHGKPSQSAVAAITLTIND--------------LNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGN--AFR------IDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQV---FYSIVRGD-TSAFAI-NAMNGV-LTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPP-----VFN---SQSYIG-SVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINS--TSGV--------IMTTTPLDFEEKSQYGLEVTATDS------KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVK---VSASDRDS--FGSLSYSIVGGKDSDK--FSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARI------------TYNLSR--NDAFMIGASSGVITLAQPLDRENKSTYDLAIQAR-----DHGTP-----PQASSITIRVTVIDINDHRPLI-------------NSSSLRGSVREN-QPKETHVMRILASDADTGLNAELTFSLLSNEHKSV 1766 HSP 7 Score: 135.961 bits (341), Expect = 2.987e-32 Identity = 162/652 (24.85%), Postives = 272/652 (41.72%), Query Frame = 3
Query: 255 GRVTLRRPIDREEYCSKSNKHQTYINSQCCG---GQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTED----FVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
GR+T+ +DRE S + I+++ G F+ I D NDNSP F I E I SR+++ A D D+ N V++ ++ D ++ +L VK +I+RE + T+ A D G P ++ + V D ND P F+ Y ++E+ +L + +D D G N + + S ++ F+++ T GV + + LD+E ++Y + A D +++ V + V N+ND P F Q N S + E + + V +D D+ S++ I ++S + + + ++ DRE +L+ + + +D G L + + I D NDN+P F S Y + EN + + ATD DEG N + Y +S + F I ++GV+ LD E + I A+D G P ++SS+ + V V D ND++P ++ S + EN+P T+V ++ +D DT +LL S +FT+DN +G I TKV LDRE + I + D G D V ++++D++DN P
Sbjct: 1258 GRITVVGVVDREALAS----YNLTISAKDSGVPPWVSTAFVAITVADE--------------NDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDE-------------GSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDE---KRFKINST-SGVIMT-TTPLDFEEKSQYGLEVTATDSKYTAKTN---VTIRVINLNDITP--AFTQQNYTAS-------VRENSPTSTSVVKVSASDRDSFG-SLSYSIVGGKDSDKFSIDQRSGIISTADV--------LDRELVSLYAIQVRVTDA-GNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFK---LAATDADEGTNARITYNLSR-----NDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADT----GLNAELTFSLL-------SNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVA-----DKGNPSLSSVAD-----VIIDVIDEDDNCP 1822
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 192.2 bits (487), Expect = 1.062e-49 Identity = 198/709 (27.93%), Postives = 302/709 (42.60%), Query Frame = 3
Query: 432 NDNSPTF-----PEKTYYKEIL-ENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTD-DDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPG-PTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIA--SNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNN--DYFSLTPDYGMLCAMEKLPPIGD---YKTVIVAEDGDFNNSRKQEFLINIHI 2510
NDNSP P K I ENS IN+ I+ + D D +I ++ + + F+ ++P+ DRE + TL D G P R +++ V D ND P F+ Y I E G +L L D D G+NG +S S T + FQ+ + LD E ++ + + A+D G P++ + V V + + ND+ P + + IS EG + + V TD D IT EI +S + N + E N +T + +K DRETK+L+ +++ D G QL + K+E+ I DINDNAPVF Y+ + EN + + ATD DEG N + Y I + + FSID +TGV+ T+ LD+E + S+ ISAKD G + + + V V + DN P Y+F +YEN P GT VG+V T KD + ++ G PT +F +D+ G I +DRE +Q A+IA PL + + +V + +LD+NDN+P +V ++ + + V + VDLD G+N VR + +N + G++ KL GD Y ++A D + S Q + IHI
Sbjct: 307 NDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYFIQLQKPL-------DRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSY---SITGGNDLGWFQVD--FQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTIS---------EGASIGATVLQVSATDVDSGDNGRITYEISSSDA-------QVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKD-HGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPGKLL----QVTATDADEGTNAVISYDI--IGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDKN------GSISYAIVSGDPT--------NLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPL------------SAQATVNIEVLDRNDNAPQF------STSSVIVDI--------DGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLWINSTSGVIKLARKLTD-GDETQYTVQVLASD---SGSPPQHSTMTIHI 936 HSP 2 Score: 189.889 bits (481), Expect = 6.903e-49 Identity = 187/705 (26.52%), Postives = 312/705 (44.26%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--SINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVF-----YQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSIT-CEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVR---VTMKNNDYFSLTPDYGMLCAMEKL-PPIGDYKTVIVAEDGDFNNSRKQEFLINIHI 2510
NDN P FP Y I E+ +N+ + A D D G Y I + F L T +I K +DRE D + + A D G P G I + +LDEND P F+Q Y I E+ G+ +L + D+DSG+NG I +I++ + + I F L + + K LD+E N Y+FN++A D G P ++ A V + V + ND+ P + + +K I + + I N I + VTD D+ +S T +I + +E Y I+ + DRE + +++ +D +G+ + + + D+NDN+P F+S Y + E N + + ATD DEG+NGTV Y I+ D +F +D +G+V T LD E++ V+I I+A+D G ++ S + V + D NDN+P S Y + E IG V +V+ TD D+ N + + + +F ++ ++G ++TK LDRE S F ++A D+G Q ++++ +T++ D NDN+P+ P F NE P + D DEG N+ + + NN FS+ G++ + L + ++ ++I++ N + ++N+ +
Sbjct: 89 NDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNT--ATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSI---FDLDSSTGVIRTK--QNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTN--------IAYILVTDKDSNTNSQTELKITNGDDEGCFK-------VEFLGFYFIQLQKPLDRELVPFYNLTLNVTD-KGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLN---ATDPDEGDNGTVSYSITGGND--LGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISS---------SDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAK-----DHGD---PQLMSSVKVELTIS--DINDNAPVFY-----------PVEYFASIMENE---PPGKL-LQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTV 731 HSP 3 Score: 124.79 bits (312), Expect = 9.587e-29 Identity = 151/586 (25.77%), Postives = 242/586 (41.30%), Query Frame = 3
Query: 186 GRSGLKSDSFYLSEDTDSFQL--INGRVTLRRPIDREEYCSKSNKHQTYINSQCCG-----GQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVF--YQF----NKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDT 1904
G +G S S D FQ+ +G VT +P+DRE+ S + I +Q G G + + I NDN P F + +Y I E + I + + A D D G +YEI + + F+L T+ +L K Q+DRE FT++A D G P K+ L + D ND P F + Y I E+E G +LL + D D G N IS + N F + + GV + ++ LD+E +S + AKD G + TA+V V V N D+ P ++ Y F N P R+Y TTKD + SI+ I ++ TN L + IK D DRE K + ++++ + L + + + D NDNAP FS+ + + V N A D D G+NG V Y +++ + + I+ +GV+K L ++++ A D G P + S+ + +++ + ++ P+ LS Y + ++P+ V D+D+
Sbjct: 455 GDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVT----ITITAQDHGSAPKTGSTTVTVTIIDG----------------NDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQ------TGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPG-KLLQVTATDADEGTNAVISYDIIGGNN---NGNFSIDSST-GV-ISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVY---ATTKD-------------KNGSISYAI--------VSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIAR-VGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNA---AAVDLDAGKNGLVRYQLTS---NAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHST--MTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDS 975 HSP 4 Score: 119.398 bits (298), Expect = 4.256e-27 Identity = 170/715 (23.78%), Postives = 289/715 (40.42%), Query Frame = 3
Query: 444 PTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETI------NKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS---ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQF---------RDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM--KNNDYFSLTPDYGMLCAMEKLP--PIGDYKTVIVAEDGDFNNSRKQEFLINIHIKEDP 2522
P F +Y +L + ++ + +A D D G Y I + NE + F + F K L ++ + + + + A DGG P + + + D ND F + + E+ G + L D I + SS ++ F + + ++ +LD E + N Y A + A+V V VT++ND+ P VF S+ I ++E + + +K D D ++ + T + F++N+ T E+ DRET + + + + +D N L T K+E+ + D ND PVF Y + E+ + + IN + A+DKD G+NG ++Y ISN ++ F ++ TG + LD+E + + I+A+D G+ SS+V + VNV D NDN P + + EN G VG+ +D+DT N SQ + F++++ + +I T +D E + G+D F+ + + S+TV + D+NDNSP + P A ++ + T T E D D N KV ++ NN YF+L P G L + ++P P Y+ I A DG SR+ + ++++ KE P
Sbjct: 944 PKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNE--EGLFGI----FPGGK---LYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISS-----ESHFAVDVRSGQITTRV--RLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAP--VF-------SRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINS----------STGELHLSKTLDRETTSSYNLVVKATDASNAN-LYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLN---ASDKDIGQNGLIKYSISN--GNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMY-----------SQTPSKTFSVNSATCEITTIAAIDLET---------------MPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFV---SPPAAAAGSSLN-VMTITAE---------------DPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQIPDNPT-IYQLTIQASDGG-QPSRQTQTVVSV-FKEGP 1569 HSP 5 Score: 116.316 bits (290), Expect = 3.595e-26 Identity = 149/543 (27.44%), Postives = 227/543 (41.80%), Query Frame = 3
Query: 192 SGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETI--NKYSFNLV--AKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDIN-DNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKI-KHVSIEISAKD-LGVPVRSSSVKLIVNVKDTN 1799
SG D F+++ T G + L + +DRE S + + ASN N I+I V D ND P FPE Y I E++ I S + A D D G+ Y I N N F V++ LIV +D E E T+ A D G P + + VLD ND P F + ++E+ TG + D+D+G N I+ + S Q TF ++ + I+ +D ET+ + SF LV A D G P S+ + V VT+ ND+ P V + P + + + + T +D D N +T I S + Y N + L+ ++I + T++ ++I SD G +QT + + K+ P FSS Y G V EN+V + +LA NG +EYY+++ D K F + K+TGVVKT G+D E + ++ + A D G R+SS + + V+D N
Sbjct: 1200 SGTGMDKFFINSST-------GELHLSKTLDRETTSSYN---------------LVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSIS--NGNLAAMFD------VESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYS---QTPSKTFSVNSAT--CEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFV----SPPAAAAGSSLNVMTITAED---------PDRNSNGKVTYSI-ISGNNGYFNLHPSTGQLQ--MIHQIP-------DNPTIYQLTIQASD--GGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVT---VLAAYPQSSLNGNIEYYLTS--DSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 6 Score: 100.523 bits (249), Expect = 2.217e-21 Identity = 139/569 (24.43%), Postives = 223/569 (39.19%), Query Frame = 3
Query: 210 SFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXX--NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKL-----MTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD---NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTL---HFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGL-DYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYV 1874
S SE + + +G++T R +DREE + + + ++ ND T K+ + V NDN+P F Y + E S S + A DAD+ +N ++ L M + F+++ L + +DRE + A D KI + V D ND P F + Y + I E + G +++L DKD G NG I S +N ++ F + L + LD+ET Y + A+D G P SST V V V +VND+ P +F Q + + E + +D D N + + +T ++F +N+ T EI + D ET F +V + +G +L + V + D NDN+P F SP ++N I A D D NG V Y +++ YF++ +TG ++ I + D I ++I+ A D G P R + + V + P + Y + EN+ GT V
Sbjct: 1088 SLISSESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAM-----------YNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADE-------------GDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKY---SISNGNLAAMFDVESATG--RLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAP--LF-------PTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNS----------ATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGS--------SLNVMTITAEDPDRNSNGKVTY---SIISGNNGYFNLHPSTGQLQMIHQIPDNPTIYQLTIQ--ASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSV 1595
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 171.785 bits (434), Expect = 3.049e-43 Identity = 143/494 (28.95%), Postives = 240/494 (48.58%), Query Frame = 3
Query: 435 DNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF--VDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFY--LNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDT 1904
+N P F + E++++ + ++ A D D G+ Y + P++N LM+ + +D ++ K +DREF+DR F + A DGG+P +G + + VLD ND P F + IY I E + G +L +R D DSG+NG++ +S + + F + + A+ ++ KLD E + Y+ + A+D G PPRS+T V++ + +VND P QF+K K Y+ I E + ++ V+ TD C+ ++ E F+ ++ N NR E++ K D E + F +V + +G L +++ + D+NDNAP F S + ++ EN V + A DKD G NG + + S + +D+ FSI++NTG + LD EK+ + I A+D GVP + + ++ + + D NDN P+ Y + EN GT V +V D D+
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMS-PSQN------LMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDN--SAFSIGEV--SGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTP-----QFSK---KVYSAT-IREDVPVNQLVTTVRATD---------CDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGV-FNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYA---VGQEFYRVQAYDKDHGTNGEITF--SFMQNDLP--FSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDS 471 HSP 2 Score: 162.54 bits (410), Expect = 2.350e-40 Identity = 149/558 (26.70%), Postives = 249/558 (44.62%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNE-NFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQN--TFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQ---ESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN 2087
ND +P F +K Y I E+ +N ++ A D D G +EI N+ NF ++ E + VK ++D E I + A D G+P +T + + ++D ND PQF ++ I E+ G E ++ DKD G NG+I+ +F +QN F +++ G+++K +LD E + K++F + A+D G P + TA + + + ++ND+PP S++ I E + + VK D D+ ++ I +S F +N I + TK ++ S+ SD L T + V + D N +AP F Y VKE+ + +LATD+D G N + Y I+ +V + FS+D+ TGV+KT LD EK+ E++A D G+P + + +++ D NDN P Y ++ E+ G V +V+ +D D N + I + ++ FTID+ G I T LDRE + ++A++
Sbjct: 228 NDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGE---------VRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSF-------MQNDLPFSINENTGGISIK--EELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPK---------FSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRINPQGL-----------ITLSCTLNYNTKHVYVFSVSASD----GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLT---VLATDRDTGSNAKISYSIATLVPE----FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIY----------SFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATD 726 HSP 3 Score: 150.984 bits (380), Expect = 1.031e-36 Identity = 183/688 (26.60%), Postives = 293/688 (42.59%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSI-EISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKA-----VNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNN----DYFSLTPDYGMLCAMEKL--PPIGDYKTVIVAED 2459
NDN P F Y +I E+ I + A DAD G Y I + + + + + V ++DRE + + A D G PPR + + +LD NDC PQFS+ +Y I+E + +R D D G+NG++ S + N F +++ V +K KLDYE I ++ + A+D GQP + V++ + +VND+ P V F I + YA + + + V+ D D+ + EI SF N L + N T I K + DRE K F + + +G+ + T ++ + + DINDN P FS Y+ + EN + + A D D G V +S+ D F I+ G++ L+Y KHV + +SA D + SS+ + VNV D+N + PE YS E+ E+ +GT V V TD+DT N K ++ T P F++D +G I T LDRE F + A+ D+G + + V ++I D NDN P+ + KP +A + P I+ S + D D G+N+++ + +N F++ G++ ++ L I +Y+ +VA D
Sbjct: 122 NDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAF-------SIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGND---MNFFSINRINGEVRVK--QKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYA---VGQEFYR------VQAYDKDHGTNG---EITF---SFMQNDLPFSI---NENTGGISIKEELDRE-KVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQ---VKAIDPDSGPTNVVYSIVSSSGHD--RCFRINPQ-GLITLSCTLNYNT-KHVYVFSVSASD---GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISY----------SIATLVPE---FSVDETTGVIKTAGSLDREKVDTYRFEVTAT-----DHGIPQLKA-----KSFVYIHIADVNDNDPVFL---KPSYEAKVREDIRPGGRVIEVSAS----------------DADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATD 726 HSP 4 Score: 149.828 bits (377), Expect = 2.220e-36 Identity = 165/599 (27.55%), Postives = 264/599 (44.07%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDF---VDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS-QTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN-----RVNEIVTINKDPILATDKDEGENGTVEY-YISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
NDN+P F + I EN + AYD D N ++ F M D ++ + +K ++DRE + + F + A D G P ++G +I + +LD ND P+FSQ Y I E+ G +L ++ D DSG + + SS+ D F+++ Q L + L L+Y T + Y F++ A D SSTALV V VT+ N P +F + + Y+ + E + + V TD D +++ I+ I T F ++ +T V IK+ DRE + + +D GI QLK + + + I D+NDN PVF P Y V+E+ RV E+ A+D D G+N + Y + SN D + F+ID G+++T+ LD E I + + A D G P +SVK+ V ++D D+ P + Y + E+ P + V V +D + ++ P Q+F I+ +G I T + LD E S+ + A+ L F +T +V V + D NDN+P++
Sbjct: 333 NDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDH-------------GTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPT-NVVYSIVSSSGHD--RCFRINPQGL----ITLSCTLNYNTKHVYVFSVSASD---GMLSSTALVYVNVTDSNTHAP-----EFKR---RSYS-AEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVD--ETTGV--------IKTAGSLDREKVDTYRFEVTATD-HGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVS--------ASDADIGKNAQIIYSFASN--GDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSP-----------QVFDINPNTGAIQTLMKLDYETQSEYRLTVRAT----------LSPFFTET---TVMVYLKDINDNTPVL 854 HSP 5 Score: 113.235 bits (282), Expect = 3.271e-25 Identity = 99/366 (27.05%), Postives = 164/366 (44.81%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV 1529
N ++P F ++Y E+ E++ + + + +A D D SY I L+ E VD ++ +DRE +D F + A D G P K K+ + + + D ND +P F + YE K++E G ++ + D D G N +I +FAS N D Q TF + T G+ ++ + LD ETI +Y +VA D G PP ++ V+V + +V DSPP F KP+ + + + E T + VK D ET + N T I++ + D ET++ + +++ + ++ + V +KDINDN PV + V+E +V
Sbjct: 537 NTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIAT----------LVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFAS--NGDGQGTFTIDST-QGI-IRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPP-----LFEKPLYE----VTVPEDTPPRSPVITVKAKSQDLSP-------ETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRAT----LSPFFTETTVMVYLKDINDNTPVLEAFHMNINVQEGKV 868 HSP 6 Score: 105.916 bits (263), Expect = 5.895e-23 Identity = 119/469 (25.37%), Postives = 207/469 (44.14%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIET---SQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL---ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVD 1820
NDN P F ++ Y+ I ENS+ + + A D D P V Y I + D F++ N Q ++ + ++ F++ A DG + + V D N P+F + Y ++KE G +L + D+D+G+N KIS + A+ + F + +T GV +K LD E ++ Y F + A D G P + + V + + +VND+ P F KP + R I G VI + D + I + Q +F +++ T ++ K DRET + +++V +D +G + + K++VI++D+ D+ P+F P Y V E+ T + P++ A +D + Y I V + F I+ NTG ++T++ LDYE + + A + + ++V +KD NDN P ++
Sbjct: 436 NDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNV-VYSIVS-SSGHDRCFRI-------NPQGLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPE-----FSVDETT-GV-IKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDP-----VFLKPSYEAKVREDIRPG---GRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDS--TQGIIRTLK--------PLDRETIPEYELTVVATD-QGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPED------TPPRSPVITVKAKSQDLSPETGMMYSI--VRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRAT---LSPFFTETTVMVYLKDINDNTPVLE 855
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 164.466 bits (415), Expect = 5.932e-41 Identity = 171/590 (28.98%), Postives = 251/590 (42.54%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVL----ENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
NDN P F +Y E EN++I I A D D F + + IE+ N + E F + ++ + +DRE D T+ AVDGG K + + VLD ND P FS+ Y I+E + H+ +D G N ++ + S N D + TL+ L S++D+E I + AKD G PP A V + V ++ND+ P QFN + + E T V V D D+ + SF L L L N + ID+ ++ + V + G T LE+ + D+ND +PVF + Y V E + I ++ATD D GENG + Y + VD K F + +N G + LD E I+ ++++ A D G P RSSS + V V D NDN P + Y+F + ENEP+ TY+G V+ +D D N + F +D ++GKI T VLDRE + F+I+A++ G R + VTV + D ND SP
Sbjct: 593 NDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNAD---------EVFSVDGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSI-SKGNTDNIVLINSTGTLY-----LQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSP-----QFNS----SSILVRLPEDTPIGHTFYTVSVFDADSGV--------LGRVSFSL--LSNPGTLFNLDSNTGALSLTKLIDYGNSARS--YTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIE---VVATDVDSGENGRISYAFDSKVDTSK--FGL-RNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQ-------------FIVDKQTGKITTSQVLDREAKASYVFSIVATD------GGSSPR----VDKTQVTVIVRDVNDCSP 1117 HSP 2 Score: 163.696 bits (413), Expect = 1.052e-40 Identity = 175/604 (28.97%), Postives = 272/604 (45.03%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTE---------DFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPR-SSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD---NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENR-VNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMK--NYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
NDNSP+F T K ++ + + R L +A D+D +SY I + N FKL+++ D V N I +DRE +D + A DGG P G ++ + V D ND +P+FS + Y I E+ G +L + DKD G N +I ++ T+ D Q F + T GV + + +LDYE Y + A+D G + SS+A+V + V +VND+ P ++ + S Q + E T + V V+D D N ++T E S + L +++ ++ DRET F+ VC D +G + + D+ND AP F Y V EN VN +V I + A D+D G N + Y I+N + ++F+ID ++G++ T LD E+I V + + D G P S + +IVN+ D+NDN P + S Y+ L+EN P G+ V ++ D D +L+ L + P F +D G + LD E+ S F + A+ D G R T+ +S+T D NDN P+
Sbjct: 52 NDNSPSFVRGTSAKLVVFENDKDFRQKL-IAVDSDFGSNSTQSYTIV--SGNVGNVFKLISKRDTDGDLYADLVVNASSI-----GVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEI--QYSIETHSDPQAIFGIHPTT-GVIVNNV-RLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNP-VIHVSYTLGGSYQ-----VTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQS--------LDRETHDHFFLKAVCID-KGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAI----VNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIG---------ENSLILYSILTPNTP----FFLDPRKGLVTNSRTLDHEVQSSYTFQVAAT-----DGGG---RSCNATVHVSLT----DLNDNQPVF 599 HSP 3 Score: 155.221 bits (391), Expect = 4.346e-38 Identity = 190/676 (28.11%), Postives = 295/676 (43.64%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNK-QPILIVKHQIDREFIDRIEFTLIAVD-GGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPP-RSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS---ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQ--LKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENC---VTFPYIFVDLDEGENSKVRVTMKNND---YFSLTPDYGMLCAMEKL 2417
ND SP F + Y + E+ + S + +A D D + PN + + F N+ +L + +DRE R ++A D GG + T I + VLD ND P F + E G + + D D G+NGK+ N + TF++++T GV + + LD+E N+Y + A D G+ ++S LV ++V + ND+ P + N I+ Y + IN T +K DDD+ +S T + ++ + F +N+ +T I++ DRE + + + + +D Q L T L++II+D+NDNAP F S ++++ N VT I A D D G+ G VEY I V FS+D TGV+K I LDYE + ++ ISA DLG P +S V V D NDN PE + + EN+P GT V KV D+D+ N + ++ + D+ F+ID SG I T +LDRE + A+ + FR SV +N++D+NDN P K ++P V+ PEN + + DLD G N+KV ++ + + F++ G L KL
Sbjct: 1113 NDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQ----------QGPNSDITYMIVAGPKAFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIV---NGNTDGTFKINETT-GV-ISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPT---FDKNPIITWIYENVPINTNVTT------IKAHDDDSGLNSRIWYTIDSQSPRAHFKINS----------ETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTYVMEDEPFNFQVT----SITALDPDTGQGGNVEYRI---VSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTY----------SIPSGVEMDK-FSIDKHSGLIVTNSILDREKKDTYFLTVHATG---------VSYPFR-VSSTSVRINVMDRNDNPP----------KFISPVVTL--------KVPENSPARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKL 1708 HSP 4 Score: 124.02 bits (310), Expect = 1.711e-28 Identity = 126/436 (28.90%), Postives = 206/436 (47.25%), Query Frame = 3
Query: 624 VDNKQPILIVKHQIDREFIDR-IEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNN-GKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIETSQE--SFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKD--PILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYE--KIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDT 1904
+D ++ + ID D I+ + A+D G PP++ + + + E P+F Y K+ E+ M G +L +RV D +G G+IS N +S N F++ Q GV + + LDYET ++ + A D P + V + V++VND P VF Q S A+ +EG ++ V D D+ A+ + I++ + SF ++ RKT I+++ D ET H VS+ +D EG + + + + D+NDN PVF P + +V E + +N I ATD+D G N + + + + + F IDK +G + T + DYE + S+ I A D G P SS++ +IVNV D ++ P + Y F++ N IG +VG+V TD+D+
Sbjct: 2252 IDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIITRE----PKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENS------NYFRIGQR-SGV-ISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKP--VFGQ-----SGYMAQW--SEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAID----------RKTGVIRTQRALDHETIKTHHVSVRATD-EGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDV----QVLENLPLNSRLYEINATDRDSGANARLSFTV--IGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDS 2649 HSP 5 Score: 121.709 bits (304), Expect = 8.150e-28 Identity = 176/697 (25.25%), Postives = 287/697 (41.18%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVES---YEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGG-----KPPRKGKTKIILKVLDENDCEPQF--SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV-----DLDEGENSKVRVTMKNN----DYFSLTPDYGMLCAMEKL--PPIGDYKTVIVAED 2459
NDN PTF + I EN IN+ ++ A+D D G+ S Y I+ +++ +FK+ +E ++ H IDRE I + A D + KII++ D ND P+F L Y + E E ++ + D D+G G + S +T + S L LKLI LDYE + +Y+ ++ A D G PP +S L V V +VND+PP F +S+ K +VKVT D + S E+ S S ++ + ++ + I + DRE K +F+++ + ++ T+ + + + D NDN P F SP V EN ++ + D D G N V Y I + + F+I ++TG + T LD E + + AKD+ P ++ + + ++D NDN P S YS + E P GT + + +DKD+ N + L T G +++ID+ +G +Y+ + + + F IA D G+D + V + I DKN+++P F KT +I+P + V D D+ N KV + ++ F + + G + PP G + I+AED
Sbjct: 1324 NDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDS---GLNSRIWYTID--SQSPRAHFKINSE------TGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQ--DLNDNAPKFVSRNLTY---VMEDEPFNFQVTSITALDPDTGQGGNVEYRIVS------PDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSEN-----------KPTGTSVVKVTAYDRDSGS-NAELTYSIPS----GVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTS-VRINVMDRNDNPPKFISPVVTLKVPENSPARLIYT----LTVQDLDYGNNTKVLYSI--MSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYT-----LSNDTYG-------VYSIDSRTGIVYSAARFETSIKQEYNFFCIAK-----DQGQDPKMAI-----VPVRIKIEDKNNHAPQ-----------------FTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAED 1936 HSP 6 Score: 121.324 bits (303), Expect = 1.278e-27 Identity = 168/668 (25.15%), Postives = 265/668 (39.67%), Query Frame = 3
Query: 435 DNSPTFPEKTYYK-EILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQ--IDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF--SQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQAD-------------SITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFD------RETKTLHFV-SIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEG-ENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQ--IFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM 2354
D+ P F +T + I ENSK+ S I+ A + D +Y I N+ Y VD ++ V +D E L+A G G + + V+D ND P F S ++ ++ ++ + D DSG NGK++ + + + F + T + + LD ET + + D G PP+S+ V+V VT++ND+PP P+S+ + I E T V+ V TD D ++ +I T Q+S +K + + N +I KID D R T + S + + ++Q + V ++ I P F P Y+G V EN + + + TD G G + Y I N NYF I + +GV+ LDYE + + +SA D P + V + +NV D ND +P S Y + E P+GT V V+ DKD+ N G Q D F ID ++G I T+ LD E ++ A+ D G ++SVT+ +LD NDN P+ + V+ + EN+ P N + D D G N+++ T+
Sbjct: 1957 DDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQV---TYSIISGNKGRAFY--------VDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV---FTIDSTTGEITTAKL--LDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPP------LFDPLSE----VNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSD--QIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLT---VRVTDNAAGLPLGRISYNIEN-----SNYFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGAN-------------GRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRAT-----DEGSPPMH-----TDVSVTIRVLDLNDNPPVFRVPGPNDVQVL------------ENL-PLNSRLYEINATDRDSGANARLSFTV 2552 HSP 7 Score: 107.842 bits (268), Expect = 1.544e-23 Identity = 146/610 (23.93%), Postives = 250/610 (40.98%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDAD-----DLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKII-LKVLDENDCEPQFS---QLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFAS-----STNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADS--ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQ------PADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
NDN P F +Y I EN + + I A D D ++ + +E++ P F ++ T V+N + + ++ R ++ + A D G + + I+ ++VLD ND P L ++ E+ G ++ + V D DSG NG++++ S D+ N + + + LD ET + + V D G PPR++ + V +VND P + + R++ E T + ++ +V D D ++S + T++ YL+ + + I + D DRE ++++ D G L + V + D NDN P F+ Y + EN + + +LA D D GEN + Y I F +D G+V LD+E + +++A D G RS + + V++ D NDNQP D S YS E +EN IG + ++ D+D+ P ++ AD++F++D SG I +LDRE + A + G+D + V + +LD ND P+
Sbjct: 166 NDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHS--DPQAIFGIH--PTTGVIVNNVR----LDYEAKRSYL----IVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESI--------IAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYE-------TRVW--ENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDP-----SSGMITTATDLDREQIPQVVLTVLVHD-RGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQ---LLAQDPDIGENSLILYSILT----PNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDS-----------------PKFAITRFIIEQGNADEVFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGG----GQDSVNK------AIVNITVLDVNDEPPIF 703 HSP 8 Score: 107.071 bits (266), Expect = 2.481e-23 Identity = 116/496 (23.39%), Postives = 202/496 (40.73%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKI--KESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN----RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN P F + Y I E + + I A D D G Y + N+ + VY +D++ I+ + + F IA D G+ P+ + +K+ D+N+ PQF++ YE+ I S + ++ D D NGK++ S N + + ++ G +++ + +++ ++A+D G PP +V++ + N+ D PP +++ AR+ I E + I V+ + + + +FY++ + + + +S +F LH V+ +G L L++ + D NDN+P F + E+ + +V + ATD D G NG V Y I + F+ID TG + T LD E + I D G+P +S++ ++ V V D NDN P D + E+ G V V TD D
Sbjct: 1744 NDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLS--NDTYGVYS-------IDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNS---TSLFVVESNTG-SVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRF--------LNQTPARVSIPENSKVGSYITTVRARASSDAQVTYSIISGNKGRAFYVDPFTGVISVASADALDYESTKNF-----RLHLVAT----PQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVT-----ATDVDSGTNGKVTYSI--WTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFD-PLSEVNIREDTRTGAVVTSVVATDTD 2201 HSP 9 Score: 89.7373 bits (221), Expect = 5.611e-18 Identity = 99/416 (23.80%), Postives = 183/416 (43.99%), Query Frame = 3
Query: 444 PTFPEKTYYKEILENSKIN-SRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQAD---SITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVI-IKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVV 1673
P F +Y+ ++ EN+ + S +++ + +A LP G SY IE N YF+ + + ++ V +D E R + A+D P + + + + V D ND +P F Q Y + E G ++++ DKDSG NG++ FA + D + +F + + GV ++ LD+ETI + ++ A D G PP + V + V ++ND+PP ++ P Q + E + + + TD D+ A+ S T T Q F ++ + + + I FD E ++ S+ T+ N +N ++ + D ++ P F+ Y + + ++ + V + ATD+D G+ G V + N N ++ TG++
Sbjct: 2302 PKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSN-----YFR------IGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVW--FAIQSGDD-KGSFAIDRKT-GV-IRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPP---VFRVPGPNDVQ-----VLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKF----------SGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFV----GQVTATDRDSGDQGRVFFVFYN---PTSNALKMNATTGII 2676 HSP 10 Score: 88.5817 bits (218), Expect = 1.094e-17 Identity = 140/514 (27.24%), Postives = 218/514 (42.41%), Query Frame = 3
Query: 993 LDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDD--DNQADSITCEIETSQESFYLNALK-TNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQT-NKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLI-VNVKDTNDNQPEVDLSFY---SFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTID----NESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNN-------DYFSLTPDYGMLCAM-----EKLPPIGDYKTVIVAEDG 2462
LD E ++ Y+ +V +F PP+S T L V+V ++ND+ P+ V A++ + E KD L+ V D N S T F L + + T+ L S I DRE + ++I SD G N +L + ++D NDN P FS+ Y G + EN ++ +I + + A+DKD G N ++Y I D + F I TGV+ + LDYE + I + A+D G + SS ++ + V D NDN P + +S+ S+++ EN IGT V +V+V+D D+ N G T + D F++ N+ I LDRE + +D G D R T E S +N+ D ND +P N V+ + N VD D G NS++ T+ N +F++ P GM+ E++P + TV+V + G
Sbjct: 20 LDREKVSAYNLTIV--EFSTPPKSYTVL--VYVQDLNDNSPSFV--------RGTSAKLVVFE-NDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVN-ASSIGVDRERLDSYVLNISASD--GGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPEN-IDVGTSILQ--VSASDKDIGTNAEIQYSIE-THSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKN-------------GEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVC-----IDKG-DPPR----TTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNA--------------VDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQV--VLTVLVHDRG 474
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Match: EDO30364 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T100]) HSP 1 Score: 159.073 bits (401), Expect = 2.809e-39 Identity = 183/686 (26.68%), Postives = 291/686 (42.42%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLE-NRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVV----LDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTM---KNNDYFSLTPDYGMLCAMEKL--PPIGDYKTVIVAED 2459
NDN P F Y E E S + I A DAD G + + EN Y + V I + Q+DRE + FT+ A D G P + + +K++D ND P F+ Y ++E++ G +L + DKD G N K+S + + F + + + L+ E Y+ L A D R T V + VT+ ND P QF + YA + E + V TD+D + ++ +Y+++ T+ + N T I + DRE + + I+ + GI L+ + + I+D+NDN P+FS Y ++E+ + + ++ATD DEG NG Y I+ D + F ID NTG++ LDYEK ++ +SA+DLG P + + + ++V D +DN P YS ELYEN G +V VN TD D + ++KR+ +I+ S D +F I +SG I L+RE ++ + A + L K L + + +LD NDN+P + V++V + I +T + + D DEGE+ ++ T+ N F + G+L L Y V++AED
Sbjct: 1288 NDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDAD---IGDNAAVLYSIVENVTDYVTVNAITGV-----ISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGV----LYTRFAIDPDTGNITTR--EPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVP-----QFTQ---SGYA-FSVREDVKVGHTVGRVATTDEDIN--------DNARVRYYISSGNTSLMFSVNETTGIISTTSTLDRE-QNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQ---VIATDPDEGANGQFTYKIT--AGDTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIE----------SGNTDSMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSL---------VPAVITVLDVNDNAP--RFDSESYVRSVLEDTGPITDATILTVKAQ----------DGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAED 1905 HSP 2 Score: 145.591 bits (366), Expect = 3.932e-35 Identity = 164/643 (25.51%), Postives = 266/643 (41.37%), Query Frame = 3
Query: 192 SGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQAD--SITCEIETSQ-ESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSF--------YSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN 2087
SG+ F + DT G +T R P++REE S + + ++S + + I D ND+ P F + Y + E+ K+ + D D Y I N + LM V+ I+ +DRE + A D G P + T +++ + D ND +P FS+ +Y + ++ES +++ + D D G NG+ + + D+ F + + +K +KLDYE + Y+ + A+D G PP + VE+ V++V+D+ P F+KP + A +Y E T+ + V TD D +A + IE+ +S +L ++ + T +RET + + + + + K + + D+NDNAP F S Y V E+ I + A D DEGE+G + + I V + F +D TGV+ LD E S+ + A+D G P SSSV + + V D NDN P + +F + EN G VG V D DT I T+ + F ++ SG++ T++ LDRE SS + ASN
Sbjct: 1439 SGVLYTRFAIDPDT-------GNITTREPLNREETGSYTLTLRA-VDSAIRAREGTTRVIITVTD--------------ANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTS------LMFS--VNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDV---FYIDANTGLITIK--AKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAP-----VFHKP--RYSAELY--ENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVI-----TLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLED-TGPITDATILTVKAQDGDEGESGEIIFTI--VSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLDTKNLIYYYI-------------TNTEEQKYFILNETSGELRTRITLDREDSSVHYLYVKASN 2016 HSP 3 Score: 128.642 bits (322), Expect = 5.511e-30 Identity = 162/601 (26.96%), Postives = 260/601 (43.26%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPI-SKQYARIYINEGTTKDMVICLVKVTDDDNQADS-ITCEIET--SQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKEN--RVNEIVTINKDPILATDKD-EGENGTVEYYI-SNVVDDMKNYFSIDKNTGVVK---TILG-LDYEKIKHVSIEISA-KDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
NDNSP F YY + EN + + + A D D SY + L T +D + + ++RE TL AVD R+G T++I+ V D ND PQF+Q Y ++E G + + D+D +N ++ + SS N + F +++T + S LD E Y+ + AKD G P S V + + +VND NKP+ SK + + E + V TD D A+ T +I + + FY++A N IK+K+D+ E +L+ +++ D G L +E+ + D++DNAPVF PRY + EN R + ++T+N ATD D E + V Y I S D M F I + +GV+ T G L+ E ++++A + + + S V ++ V D NDN P D Y + E+ G +T K D + I ++ G G +F +DN++G + LDRE +S ++A D G+ + ++V + +LD NDN P++
Sbjct: 1393 NDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSG---------VLYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRY-YISSGNTSLM--FSVNETTG--IISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVND----------NKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDA--------NTGLITIKAKLDY--EKTSLYNLTVSAQDL-GTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVN-----ATDIDAEASHKRVYYRIESGNTDSM---FLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLED--TGPITDATILTVKAQDGDEGESGEIIFTIVSGNENG-------VFQMDNKTGVLTRTRPLDREDTSFYSLVVMAE-----DKGEPAL-----SSSVTVNITVLDMNDNLPIL 1931 HSP 4 Score: 128.257 bits (321), Expect = 8.502e-30 Identity = 171/670 (25.52%), Postives = 279/670 (41.64%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD--NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL---ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKV--RVTMKN-NDYFSLTPDYGMLCAMEKL 2417
ND SP F + YY + E++ I A D D+ + Y F Y T D +IV +DREF + + A + + T++ + V D D +P F+ +K+ E+ G + + DKD G+ SI N D F + ++ +++LD E + +Y + AKD S V V V +VND+PP F+ P Y Y E + + I VK D D + A + +E + +NA+ L + + DRE + +I +D+ G+ T + + + DINDN+PVF++ YY V+EN+ P+L A+DKD G N + Y +S V + F+ID +TG + T L+ E+ ++ + A D + R + ++I+ V D ND+ P+ S Y+F + E+ +G VG+V TD+D + N + +S +F+++ +G I T LDRE ++ I A D+G SV + I D NDN P+ K E F+KT + I D DEG N + ++T + +D F + + G++ KL
Sbjct: 1083 NDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYSSNGAEAKF--YVSRSTGD--------IIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDTISYSI-----ANGDPYGLFTIDNVTG--EIRTVAELDRENVTQYELFVQAKD-SVNLVSDLLKVVVQVEDVNDNPP-----VFSMP---GYTIEYWEE-SPEGTSILQVKAIDADIGDNAAVLYSIVENVTDYVTVNAITGVISLGSSQ---------LDREVEEYFNFTIRATDS-GVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQP------AGTPVLVVTASDKDVGTNAKLSYVLSGV---LYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYI-----------SSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAK-----DHGIPALES-----NTSVMITIEDVNDNKPLF---SKSVYNVTLRESVFLKTQVVQ-----------VIATDPDEGANGQFTYKITAGDTDDVFYIDANTGLITIKAKL 1671 HSP 5 Score: 119.398 bits (298), Expect = 4.126e-27 Identity = 133/516 (25.78%), Postives = 218/516 (42.25%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRK-GKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISK-LDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVI--CLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFS-SPRYYGIVKENRVNEIVTINKDP---------ILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIK---------HVSIEISAKDLGVPV---RSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKD 1901
NDN P F + +Y + E + I+ A DAD FG +YE+ YF + ++ + IL D + + + +F+L+ DGG ++ + + + D ND +P+F+ + Y I E+ G + + DKDSG NG++S N ++ D F +++G L ++ LD ETI Y+ + A D G R + V V + ND+ P I I+EG V+ + V D +T + F LN+ + S DRE K + + I +D G + + V I D+NDN P F +P ++ ++T+++ P I ATD D NG V Y +S D +F +D TG + LD E + ++I+A D P+ +S++V++ + V+DTNDN P+ Y L E G+ V +V+ TD+D
Sbjct: 383 NDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELRGGQA---AYFSVNADNGTISAAQIL------DYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAG---DDGGHF----SINGSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQIT--------DGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFTLNSATGRLQI---------SPTGLDRELKDSYDLIINVTD-NGSPPNTNSTTVHVTILDVNDNTPAFDPNP------AQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSG---DEHGFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQD 855 HSP 6 Score: 117.087 bits (292), Expect = 2.312e-26 Identity = 188/805 (23.35%), Postives = 318/805 (39.50%), Query Frame = 3
Query: 210 SFYLSEDTDSF---QLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTX-------XXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQP-PRSSTALVEVFVTNVNDSPPNIVFYQF------NKPISKQYARI----------------------------------------------YIN--EGTTKDMVICLVKVTDDDNQADSITCEIETSQES-FYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKI-YTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDY--FSLTPDYGMLCAMEKL 2417
++ LS D F + G +++R+ +DRE Q N+Q G + I + D V + I V D NDNSP F + Y + E ++ S + A D D G Y I +EN + + + +K+ ++ K + ++R T +++ V D ND +P F+Q Y + E+ TG +L + D+D G NGKI+ TN + + F ++ + + + +D E ++ + + A+D G+P R + A V + V + ND+ P F + N P+ + Y+N E ++ +VI V TD D ++I E+ FY+ +R T +I DRE K ++ +++ ++ Q T ++ + + D+ D+ P F+S + EN + N I A DKD G+ T+ Y I+N D F+ID TG ++T+ LD E + + + AKD V + S +K++V V+D NDN P + Y+ E +E P GT + +V D D N + ++N+ T++ +G I LDRE+ F I A+ D G + SV + ++D NDNSP+ D ++++ EN P D D G N+K+ + Y F++ PD G + E L
Sbjct: 747 AYSLSGDEHGFFRLDPVTGELSVRKELDRE-------SPQMSRNAQ---GDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRKCEVEKLVRHYNWHKKNCVLCKES--KCSVER------------------TYVVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKL---TNGNKDDAFSINNVTGEITVAGV--IDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSFTGYEGEIAENSPVGSTITMVPDQKISSSTLRPRSSPRAPAALLTAREKRPITLINDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYSSNGAEAKFYV----------SRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQ-DTTTQVHITVTDVIDDKPYFNSSSLTVKLSENAS---IGTNVTKITALDKDIGD--TISYSIAN--GDPYGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKD-SVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSIVENVT------------DYVTVNAITGVISLGSSQLDREVEEYFNFTIRAT-----DSGVP-----SKSSTASVAIKLVDINDNSPVFNNTDY---------YAYVR----EN-QPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYTRFAIDPDTGNITTREPL 1461 HSP 7 Score: 108.612 bits (270), Expect = 8.335e-24 Identity = 155/607 (25.54%), Postives = 254/607 (41.85%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQ-LIYEIKIKESEMTGLELLH-LRVEDKDSGNNGKISINFASSTNQDIQNT----FQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEG-TTKDMVICLVKVTDDDNQADS-ITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLH---------FVSIVCSD--TEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL--ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSP 2189
NDN P F Y +I EN + + A D D G S+ I ++ +F + N ++ ++DRE I T+ A D G R ++ + VLDEND PQ + L I E G LL + D D+G+NG+++ + + ++ N+ Q+S T LD E + Y + D G PP +++ V V + +VND+ P + N S I ++EG T + + + TD D A+ + + + F+ + + V T E+ + + DRE+ + + I +D T ++ T ++ + ++D NDN+P F S Y E R++E + I ATD+D G V Y N+ D +N + V K + ++ K V K+ V + V ++ V D NDN P + S Y+ ++ EN P GT V +V+ +D+D N K T+ D F+I+N +G+I V+DRE + A D G+ R + E+ +TV D+NDN P
Sbjct: 488 NDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGG--HFSI-------NGSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFTLNSATGRLQISPT----------GLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTP---AFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFF----RLDPV-----TGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNY-----ETRLSEAARPGSNVIQVSATDQDLEYKGKVIY---NITDGDEN-----RKCEVEKLVRHYNWHKKNCVL----CKESKCSVERTYV--VIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKL-----------TNGNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAE-----DQGEPSSR--KTFAEVVITVK--DENDNFP 1024 HSP 8 Score: 97.8265 bits (242), Expect = 1.495e-20 Identity = 160/622 (25.72%), Postives = 252/622 (40.51%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVES---YEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELL--HLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFN-----------------------LVAKDFGQPPR-SSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDD-NQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEV-DLSFYSFELYENEPIGT-YVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKI-YTKVVLDREMSSQIPFAI-IASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMM 2195
+D P F + Y KEI EN+ I S + A D D G+ + YEI N D F +D+ ++ V ID E D T+ A + P +++ V+D ND P F Q +Y ++E ++ L+V D D + + + D S TL+ + LDYE ++F+ +VA + + S+ A V + + NVND+ P +N + ++ I GT I + TD D ++T E+ Q +++ +V + T +D+D T + S+V D G Q + V ++D+NDN P F+ Y + EN + + ATDKD GENG + + IS D +FSI+ +G+V T LD E I ++ +SA D GV R V+L VNV D NDN P++ D + + E GT + + D D N G + D FT+++ +G++ + LDRE+ I + N +P +T +V V ILD NDN+P
Sbjct: 147 SDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGD---VGINNPILYEIISGNS--DGVFT------IDSNTGVITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSDKFAIDPTSGTLY-----INKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEE-----ITPGTH----IADITATDADLGTFGALTYELRGGQAAYF-------SVNADNGTISAAQILDYD--TLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQ---VTATDKDSGENGRLSFNIS--AGDDGGHFSIN-GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSN-------------GQLTYSMSGGDSRFTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSP-----------PNTNSTTVHVTILDVNDNTPAF 704 HSP 9 Score: 97.8265 bits (242), Expect = 1.756e-20 Identity = 113/437 (25.86%), Postives = 188/437 (43.02%), Query Frame = 3
Query: 663 IDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQF------SQLIYEIKIKESEMT-GLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETI---------NKYSFNLVAKDFGQP---PRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYIN----EGTTKDMVI---CLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPIL---ATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPV-RSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKV 1883
+DRE D + + D G PP T + + +LD ND P F S Y I + E T L+ + D D+ NGK+ A S + D F+L ++++ +LD E+ ++ ++ A D P +S+T V + V + ND+ P + +S+ AR N T +D+ + +TD D ++ CE+E + N K N VL +E+K CS + + + + D+NDN PVF+ +Y V EN + P+L A+D+D+G NG + Y ++N D + FSI+ TG + +D E + + + A+D G P R + ++++ VKD NDN P+ + Y E+ EN P+G+ + V
Sbjct: 662 LDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKV----AYSLSGDEHGFFRLDPVTGELSVR--KELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEA-ARPGSNVIQVSATDQDLEYKGKVIYNITDGD---ENRKCEVEKLVRHY--NWHKKNCVLC--------------KESK--------CS--------VERTYVVIYVDDVNDNDPVFNQSKYAADVLEN------SPTGTPVLRVHASDRDQGANGKITYKLTNGNKD--DAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSFTGYEGEIAENSPVGSTITMV 1048 HSP 10 Score: 86.6557 bits (213), Expect = 4.694e-17 Identity = 74/220 (33.64%), Postives = 102/220 (46.36%), Query Frame = 3
Query: 1449 VIIKDINDNAPVFSSPRYYGIVKEN-RVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLG--TSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASN-PNP 2096
+I+ D NDNAPVF+ Y + EN RV TI K I A D D G N V+Y SN +FS++ G + LD+E + + + A+DLGVP S +I+ V D +D P SFY E+ EN PIG+ V V D D + P L S +D +FTID+ +G I +D E + + AS P+P
Sbjct: 34 LIVDDYNDNAPVFTEQPYMAKIAENARVG--TTILK--ISAIDADSGTNSQVQYKFSNATATQTPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVG-------------INNPILYEIISGNSDGVFTIDSNTGVITVNGSIDAEKTDVFRITVKASEVPDP 236 HSP 11 Score: 73.559 bits (179), Expect = 4.542e-13 Identity = 55/177 (31.07%), Postives = 82/177 (46.33%), Query Frame = 3
Query: 681 DRIEFTLIAVD---GGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIV--FY----QFNKPISKQYARIYINEG 1184
D EFT+ D GG R+G L V D ND P F++ Y KI E+ G +L + D DSG N ++ F+++T Q F +++G L L LD+E Y ++A+D G P S V + VT+++D PP + FY + N PI + +G
Sbjct: 7 DNYEFTVYVEDDFNGGGLARRGSKFFFLIVDDYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATAT--QTPFFSLNSVNG-ELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDG 180 HSP 12 Score: 58.5362 bits (140), Expect = 1.459e-8 Identity = 43/155 (27.74%), Postives = 70/155 (45.16%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI 896
NDN+P F E+ Y +I EN+++ + I A DAD Y+ +F L ++ L + +D E +IA D G P + +T +I++V D +D P+F Q Y +I+E+ G ++ + D D G N I
Sbjct: 40 NDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATATQTPFFSL------NSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPI 188
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 239.965 bits (611), Expect = 3.277e-65 Identity = 200/703 (28.45%), Postives = 320/703 (45.52%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI--VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDD--MKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND---YFSLTPDYG-MLCAMEKLPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP + EN+ + + S+P+A D D GV Y + + F L D K P LIV +DRE D + T+ AVDGG P R + + + V D ND P+F YE ++ E+ G +L ++ +D D G NG+I + + + + ++ +T + +K LD E IN SF +VA+D G P+SS V + VT+ ND+ P + ++ I+E + LV+V+D D +++ + F L +++ +N++ Y +++ D E + V IV D+ G L TN L+V + D+NDN+PVF SP + + +EN+ E + + ATD D G N + Y N+V D +K F ID NTG VK LD E + ++A D G PV + +++ V D NDN P+ LS YSF + EN P + VG V V D D N + + +P F + N +G I + + DRE S F + A +D G+ + + VT+N+LD+NDN P++ + ++P S P++ V DLD G N+ + ++ + F ++P G + A E G ++V R L++I++ E
Sbjct: 126 NDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTA-GPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDP-VPKLLRIDRTTGIIYVK--GPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGL-VTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRP-ASDSTSDNKRKYFLQTTTPLDYERVKEYRVEIVAVDS-GNPALSSTNSLKVQVTDVNDNSPVF-SPTIFEVDFAEENQPGETIL----DVTATDADSGTNAELFY---NIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHL-------------SVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKA-----VDGGEPPRSSY-----VGVTINVLDENDNDPVVTKPSNSSFRQLSPVAS-----------PDSHVDV-VEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNE 778 HSP 2 Score: 118.242 bits (295), Expect = 1.699e-26 Identity = 155/572 (27.10%), Postives = 229/572 (40.03%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTF--QLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDR-ETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYG 2393
++V D ND PQF + I + E+ + G D+DS NG ++A + D F Q++ G +LI LD E + Y + A D G P R S AL+ V VT+ ND+ P + +S E + + VK D D + EIE S K + +R T I K DR E +L F V + +G + + + D NDNAP R G+V + I I++D + T DKDEGEN V ++ V D+ + YF ++T LDYE++K +EI A D G P SS+ L V V D NDN P + + + E G + V TD D+ N + +G S +F ID +G++ + LDRE + F + A+ D G + + +V + +LD NDN P ML S S EN+ P + V +D+D+GEN+ V + S+ PD G
Sbjct: 120 IEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNG--VADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVS---------ENSPVGHSVLQVKADDSDMGPNG---EIEYSLHQAVDPVPKLLRI--DRTTGIIYVKGPLDREEINSLSF--YVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEI-RGIGLVTHSE--GIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYF--------LQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYN---------IVGDSY-IKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAA-----DKGSPVHKG-----TATVVIKVLDCNDNDPKFML-------------SGYSFSVLENMPPLSPVGM-VTVLDMDKGENAHV--------HLSVEPDGG 620
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 241.891 bits (616), Expect = 3.312e-65 Identity = 200/703 (28.45%), Postives = 320/703 (45.52%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGI--VKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDD--MKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNND---YFSLTPDYG-MLCAMEKLPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKE 2516
NDN+P FP + EN+ + + S+P+A D D GV Y + + F L D K P LIV +DRE D + T+ AVDGG P R + + + V D ND P+F YE ++ E+ G +L ++ +D D G NG+I + + + + ++ +T + +K LD E IN SF +VA+D G P+SS V + VT+ ND+ P + ++ I+E + LV+V+D D +++ + F L +++ +N++ Y +++ D E + V IV D+ G L TN L+V + D+NDN+PVF SP + + +EN+ E + + ATD D G N + Y N+V D +K F ID NTG VK LD E + ++A D G PV + +++ V D NDN P+ LS YSF + EN P + VG V V D D N + + +P F + N +G I + + DRE S F + A +D G+ + + VT+N+LD+NDN P++ + ++P S P++ V DLD G N+ + ++ + F ++P G + A E G ++V R L++I++ E
Sbjct: 203 NDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTA-GPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDP-VPKLLRIDRTTGIIYVK--GPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGL-VTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRP-ASDSTSDNKRKYFLQTTTPLDYERVKEYRVEIVAVDS-GNPALSSTNSLKVQVTDVNDNSPVF-SPTIFEVDFAEENQPGETILD----VTATDADSGTNAELFY---NIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHL-------------SVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKA-----VDGGEPPRSSY-----VGVTINVLDENDNDPVVTKPSNSSFRQLSPVAS-----------PDSHVDV-VEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNE 855 HSP 2 Score: 120.168 bits (300), Expect = 5.143e-27 Identity = 155/572 (27.10%), Postives = 229/572 (40.03%), Query Frame = 3
Query: 753 LKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTF--QLSQTLHGVALKLI--SKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDR-ETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYG 2393
++V D ND PQF + I + E+ + G D+DS NG ++A + D F Q++ G +LI LD E + Y + A D G P R S AL+ V VT+ ND+ P + +S E + + VK D D + EIE S K + +R T I K DR E +L F V + +G + + + D NDNAP R G+V + I I++D + T DKDEGEN V ++ V D+ + YF ++T LDYE++K +EI A D G P SS+ L V V D NDN P + + + E G + V TD D+ N + +G S +F ID +G++ + LDRE + F + A+ D G + + +V + +LD NDN P ML S S EN+ P + V +D+D+GEN+ V + S+ PD G
Sbjct: 197 IEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNG--VADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVS---------ENSPVGHSVLQVKADDSDMGPNG---EIEYSLHQAVDPVPKLLRI--DRTTGIIYVKGPLDREEINSLSF--YVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEI-RGIGLVTHSE--GIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYF--------LQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYN---------IVGDSY-IKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAA-----DKGSPVHKG-----TATVVIKVLDCNDNDPKFML-------------SGYSFSVLENMPPLSPVGM-VTVLDMDKGENAHV--------HLSVEPDGG 697
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 217.624 bits (553), Expect = 2.137e-57 Identity = 190/653 (29.10%), Postives = 303/653 (46.40%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEK-PNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--SINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ + S+P+A D D GV Y + P+ N F L + VD K P +IV +DRE D + + VDGGKPPR + + V D+ND P+F + YE ++ E+ G +L +R D D+G NG I S++ AS T +Q ++ ++ + +K + +D E N F +VA+D G +SS A V + + + ND+ P I I + + I+E + LV+V+D D +++ + F L +A RK Y +++ D E + + IV D+ G L TN L+V + DINDN P FS ++N+ + V ++ATD D G N + Y I + + F I+ NTG ++ LD E ++ ++A D GVP ++ + +++NV+D NDN P+ LS YSF + EN P VG V V+D D N++ + +P + F I N +G I + + DRE S F + A +D G + + VT+N+LD+NDN+P + K N + +K S+ P + D+D G N+++ T+ + L
Sbjct: 145 NDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDAN--QLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDT---VQRLLRIDRSTGIIYVKGL--VDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFV-ANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRK-YFLQTTTLLDYERIKDYRIEIVAVDS-GNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVI----DVVATDADSGVNAELVYSI--IESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFV-------------EPDNGKFIIQNGTGTILSSISFDREKESTYTFRLKA-----VDAGDPPRSSY-----VGVTINVLDENDNAPYV-------TKPANSSYTHLKPSS-----PPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGL 746 HSP 2 Score: 142.51 bits (358), Expect = 7.363e-34 Identity = 167/557 (29.98%), Postives = 234/557 (42.01%), Query Frame = 3
Query: 750 ILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKL-----ISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN-PLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKV 2342
I++VLD ND PQFS I + I E+ TG D+DSG+NG +A S D F L Q V K+ I LD E + Y N+ D G+PPR+S+AL+ + VT+ ND+ P +F K QY + E + + V+ D D A+ + Q S + L + +R T I K DRE L +V D G N ++ + IKD NDNAP R G+V N + I++D + T D+DEGEN V ++ V D + YF ++T LDYE+IK IEI A D G P SS+ L V V D NDN P + E+ G V V TD D+ +N + + A +F I++ +G+I + LDRE + F + A++ P G + V +N+ D+NDN P ML S S NEN+ P N V D D+GENS+V
Sbjct: 138 IIEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNG--VAEYALSAGPDANQLFGL-QVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAP-----KFEK---NQY-EAELPENSPPGHSVLQVRANDADTGANG-DIDYSLHQASDTVQRL----LRIDRSTGIIYVKGLVDREEDNLLKFYVVARD-RGPNSKSSKAQVTISIKDQNDNAPAIEI-RGIGLVIHQ--NFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYF--------LQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSI-----------IESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAI-----------VVINVEDRNDNDPKFML-------------SGYSFSVNENMPPLNPVGV-VTVSDADKGENSQV 629 HSP 3 Score: 102.449 bits (254), Expect = 1.393e-21 Identity = 110/375 (29.33%), Postives = 159/375 (42.40%), Query Frame = 3
Query: 1326 KTYEI-KSKIDFDRETKT------------LHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFS------IDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSLTP 2384
KT EI ++I DRET + L F + +GI + + + + DINDN P FSSP + EN T+ P+ A D+D G NG EY +S D F +D+ V I LD EK + I D G P R+SS L + V D NDN P+ + + Y EL EN P G V +V D DT N + S ++ ID +G IY K ++DRE + + F ++A + P + + VT++I D+NDN+P + ++ V N F+ NI + + P V D DEGEN+ V + + F L P
Sbjct: 85 KTGEIYTTEIPIDRETLSDCRNLFEDDKCFLEFEVSITDMVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPEN--THTGTLFSIPV-AVDRDSGSNGVAEYALS-AGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQ---------ASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGP----------NSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQN----FVA-----NISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRP 427 HSP 4 Score: 60.4622 bits (145), Expect = 9.334e-9 Identity = 58/222 (26.13%), Postives = 90/222 (40.54%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYE--IKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y + EN + + + DAD + +E N F + N ++ DRE F L AVD G PPR + + VLDEND P ++ +K S + ++ ED D+G N ++ + + T + FQ+S + +KL + + + D G+PPR +TALV V+V
Sbjct: 588 NDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFVEPDNGKF----------IIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAEL---YYTITGGNPHGLFQISH--NSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYV 794
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 216.083 bits (549), Expect = 2.778e-57 Identity = 191/656 (29.12%), Postives = 303/656 (46.19%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEK-PNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKI--SINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRY-YGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPF---AIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL 2378
NDN+P F I EN+ + S+P+A D D GV Y + P+ N F L + VD K P +IV +DRE D + + VDGGKPPR + + V D+ND P+F + YE ++ E+ G +L +R D D+G NG I S++ AS T +Q ++ ++ + +K + +D E N F +VA+D G +SS A V + + + ND+ P I I + + I+E + LV+V+D D +++ + F L +A RK Y +++ D E + + IV D+ G L TN L+V + DINDN P FS ++N+ + V ++ATD D G N + Y I + + F I+ NTG ++ LD E ++ ++A D GVP ++ + +++NV+D NDN P+ LS YSF + EN P VG V V+D D N++ + +P + F I N +G I + + DRE S F A+ A +P Y + VT+N+LD+NDN+P + K N + +K S+ P + D+D G N+++ T+ + L
Sbjct: 145 NDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDAN--QLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDT---VQRLLRIDRSTGIIYVKGL--VDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFV-ANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRK-YFLQTTTLLDYERIKDYRIEIVAVDS-GNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVI----DVVATDADSGVNAELVYSI--IESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFV-------------EPDNGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSY-------------VGVTINVLDENDNAPYV-------TKPANSSYTHLKPSS-----PPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGL 746 HSP 2 Score: 141.354 bits (355), Expect = 1.310e-33 Identity = 167/557 (29.98%), Postives = 234/557 (42.01%), Query Frame = 3
Query: 750 ILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKL-----ISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILAT--------DKDEGENGTVEYYISNVV------------DDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPN-PLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKV 2342
I++VLD ND PQFS I + I E+ TG D+DSG+NG +A S D F L Q V K+ I LD E + Y N+ D G+PPR+S+AL+ + VT+ ND+ P +F K QY + E + + V+ D D A+ + Q S + L + +R T I K DRE L +V D G N ++ + IKD NDNAP R G+V N + I++D + T D+DEGEN V ++ V D + YF ++T LDYE+IK IEI A D G P SS+ L V V D NDN P + E+ G V V TD D+ +N + + A +F I++ +G+I + LDRE + F + A++ P G + V +N+ D+NDN P ML S S NEN+ P N V D D+GENS+V
Sbjct: 138 IIEVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNG--VAEYALSAGPDANQLFGL-QVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAP-----KFEK---NQY-EAELPENSPPGHSVLQVRANDADTGANG-DIDYSLHQASDTVQRL----LRIDRSTGIIYVKGLVDREEDNLLKFYVVARD-RGPNSKSSKAQVTISIKDQNDNAPAIEI-RGIGLVIHQ--NFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYF--------LQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSI-----------IESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAI-----------VVINVEDRNDNDPKFML-------------SGYSFSVNENMPPLNPVGV-VTVSDADKGENSQV 629 HSP 3 Score: 101.679 bits (252), Expect = 2.412e-21 Identity = 110/375 (29.33%), Postives = 159/375 (42.40%), Query Frame = 3
Query: 1326 KTYEI-KSKIDFDRETKT------------LHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFS------IDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFV---DLDEGENSKVRVTMKNNDYFSLTP 2384
KT EI ++I DRET + L F + +GI + + + + DINDN P FSSP + EN T+ P+ A D+D G NG EY +S D F +D+ V I LD EK + I D G P R+SS L + V D NDN P+ + + Y EL EN P G V +V D DT N + S ++ ID +G IY K ++DRE + + F ++A + P + + VT++I D+NDN+P + ++ V N F+ NI + + P V D DEGEN+ V + + F L P
Sbjct: 85 KTGEIYTTEIPIDRETLSDCRNLFEDDKCFLEFEVSITDMVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPEN--THTGTLFSIPV-AVDRDSGSNGVAEYALS-AGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQ---------ASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGP----------NSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQN----FVA-----NISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRP 427 HSP 4 Score: 60.8474 bits (146), Expect = 7.583e-9 Identity = 58/222 (26.13%), Postives = 90/222 (40.54%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYE--IKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFV 1091
NDN P F Y + EN + + + DAD + +E N F + N ++ DRE F L AVD G PPR + + VLDEND P ++ +K S + ++ ED D+G N ++ + + T + FQ+S + +KL + + + D G+PPR +TALV V+V
Sbjct: 588 NDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFVEPDNGKF----------IIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAEL---YYTITGGNPHGLFQISH--NSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYV 794
BLAST of Protocadherin-1 vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 207.223 bits (526), Expect = 3.757e-54 Identity = 204/740 (27.57%), Postives = 335/740 (45.27%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPN-----------------ENFD------VYFKLMTEDFVDN-KQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTK-------DMVICLVKVTDDDNQADSI-TCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRV-NEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSL---TPDYGMLCAMEKLPP--IGDYKTVIVAEDGDFNNSRKQEFLINIHIKEDPHTLNN 2537
NDN+P+FP + EN I + LP A D D G+E YE+ + N FD F+L D D KQP LI+K +DRE D E TL DGG PPR + + + + D ND P+F + +YE + E+ G +L L+ D D G NG+I F ++T + ++ +L ++ L ++ ++D E +++ F ++A+D GQPP+ A V + + + ND+ P I ++ RI++ +G D I LV+V+D D + I TC + F L +N+K Y + + D ET + V IV D+ G L N L V + D NDN P+FS EN E VT + ATD D G+N + Y + + V+ + FSID ++G ++ LD E+ + ++ AKD G+ S ++V V D NDN+P+ ++F + EN + VG V V D D N + + + ++IF+I+NE+G I++ + DRE + F + A + G D R + +V++ ++D+NDN+P + +N + + S+ V I D D G N+ + ++ + F L G++ M KL G ++ V+ D + S+ L+++++ E TL+N
Sbjct: 133 NDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAAT-ESVRRLLRLDESTG--WLSVLHRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEI--------RKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTV-VGDVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDS-GSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTT----VTATDADSGKNAEISYSLDSSVNGI---FSIDSDSGDIRVNTNLDREQKERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSPVGMVTVIDADKGQNAEMGLFIEE-------------EEEIFSIENETGTIFSTLSFDREQKTTYTFRVKAVD------GGDPPR----SATATVSLFVMDENDNAPTVTF-------PINSSYTLLPPSST-----VRTVVRTVIATDTDTGINADLNYSIIGGNPFRLFEIDGATGVISLMAKLEQKHYGLHRLVVQVTD-NGQPSQSTTTLVHVYVNE---TLSN 813
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000042783.1 (SMESG000042783.1) HSP 1 Score: 1908.26 bits (4942), Expect = 0.000e+0 Identity = 1007/1010 (99.70%), Postives = 1007/1010 (99.70%), Query Frame = 3
Query: 51 MEXXXXXXXFFCQLSELDACDSIKQVEITETTVSLFELADVSDHIGRSGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKLPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKEDPHTLNNKIRTSQGNHESKYNSEYPARSNERYFRNNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNETSFGQVSTKNPPDSLECQDFFESIPDSKYNDLSFVKNRQPESYRNDYQFKSMEPKIIEKYESADPIFHEVRNFNNISNQMPQSYNYQTIPTQFLPDPMHLYHSLGNSKSELVFQPPNKFTN 3080
MEIILLILIFFCQLSELDACDSIKQVEITETTVSLFELADVSDHIGRSGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTKKKVYIKIKVVDINDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDRE IDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAP FSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDINNKRIIMKIKNLLPGPTL TSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKLPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKEDPHTLNNKIRTSQGNHESKYNSEYPARSNERYFRNNIIYVIIGSIAAILFLLLIIILVKFRKFLINETSFGQVSTKNPPDSLECQDFFESIPDSKYNDLSFVKNRQPESYRNDYQFKSMEPKIIEKYESADPIFHEVRNFNNISNQMPQSYNYQTIPTQFLPDPMHLYHSLGNSKSELVFQPPNKFTN
Sbjct: 1 MEIILLILIFFCQLSELDACDSIKQVEITETTVSLFELADVSDHIGRSGLKSDSFYLSEDTDSFQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTKKKVYIKIKVVDINDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREIIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPAFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDINNKRIIMKIKNLLPGPTLATSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKLPPIGDYKTVIVAEDGDFNNSRKQEFLINIHIKEDPHTLNNKIRTSQGNHESKYNSEYPARSNERYFRNNIIYVIIGSIAAILFLLLIIILVKFRKFLINETSFGQVSTKNPPDSLECQDFFESIPDSKYNDLSFVKNRQPESYRNDYQFKSMEPKIIEKYESADPIFHEVRNFNNISNQMPQSYNYQTIPTQFLPDPMHLYHSLGNSKSELVFQPPNKFTN 1010 HSP 2 Score: 85.8853 bits (211), Expect = 1.271e-16 Identity = 44/44 (100.00%), Postives = 44/44 (100.00%), Query Frame = 2
Query: 3080 YTNAQILNENNSPVFNNSQSTSIVVNTNKAKTTNVKSPFQSTFV 3211
YTNAQILNENNSPVFNNSQSTSIVVNTNKAKTTNVKSPFQSTFV
Sbjct: 1011 YTNAQILNENNSPVFNNSQSTSIVVNTNKAKTTNVKSPFQSTFV 1054
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000033582.1 (SMESG000033582.1) HSP 1 Score: 408.297 bits (1048), Expect = 9.319e-125 Identity = 272/814 (33.42%), Postives = 441/814 (54.18%), Query Frame = 3
Query: 108 CDSIKQVEITETT-VSLFELADVSDHIGRSGLKS----DSFYLSEDTDS--FQLINGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTXXXXXXXXXXXXXNDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYG-IVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDM-KNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIK--TSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKLPPIGDYKTVIVAEDGD-FNNSRKQEFLINIHIK 2513
CD I + +TE L D+ + S L S D+ Y ++ +S F L +G++ + P+DRE+ CS + +CC CC+FIGI S + K YI++ + D NDN P FP+ + EN +I + LP A D D +G++SY++ +++ F++ E DN+ +L+ K +IDRE ++A+D GKP + G IIL+V D ND P F + + ++E+ +G E+ ++V D D G N ++S N T+Q Q F+L Q G++L+L S LDYE N + F ++AKD G P STA V V VTN+ND PP I+FY + ++ + E K I L+ VTD D++ I CE+ ++ FYL + ++E +K +E+++ I+FDRET +++ ++I CSD+ I++L Q+ ++++ I D+NDN P+FSS ++G I++ + ++ V + + I TD D G N ++Y++ + ++ YFS++ +K +DYEK K + A D G P ++S ++ ++V D NDN+PE+ FY+F + E +PIGT +G++ +D DTD + I +L Q + +F I+N +G I T+VVLD E + F + N N KD + + +++TV I+D NDNSP + LK+ V+ +S K T +I C FPY F+D DEG N++V VT+K N FSL + ++C G + ++ +D + N SR+ E LINIH+K
Sbjct: 23 CDYISVITVTENIPYPSSSLIDIGHLLLTSSLISQAEKDNIYFTDRKNSQPFSLSHGKLIVTGPLDREKICSPQTDQN--LIQKCCESSCCMFIGITSPNR--KINYIRVNIEDENDNEPIFPQSYIKIAVHENVEIGHTLVLPKAEDLDTPSYGIDSYKLIS-DKSCGSCFEVKNEP-KDNRL-VLVFKTKIDRETNSVFNLLVLAIDRGKPSKTGSLSIILEVEDINDNRPHFEESTISLSVEENGRSGREIKRIKVTDSDIGANSQMSYNIEDYTSQ-AQRYFKLFQIKDGISLQLQSTLDYENKNIFEFRIIAKDQGTPYLMSTATVTVRVTNLNDEPPEILFYNRGSIVDPNSIQLTLPENGPKHQTIILIHVTDKDSKLSDILCEVSHPKDVFYLRETENVNIIEKKKIFELQNLIEFDRETTSIYRITITCSDSNTISKLTQSVEIQMKIDDVNDNPPIFSSSFHFGKIMETDLTDQDVHMTEGVIQVTDADIGMNSRIKYHLKDALNSTDSQYFSVNSEYPQIKNKEPIDYEKSKQFKFFLVAVDGGKPALTASTQITISVSDANDNRPEIGNKFYTFSVLEEQPIGTKIGQIVASDADTD---QLNRDVIFEMLSLDGTKRRQRQNDLFIIENNTGFIKTRVVLDHEKDQHVSFLVRVRNTNEYVGTKDKLDFYSSS--VAITVKIIDINDNSPKLALKESLIVEQAGSCLSSQKPIIITTSDIASNLCSEFPYTFLDADEGLNAEVVVTLKENPNFSLDMGHNLICLKNLHLSPGYFTVNVIGQDRNGGNGSRRAECLINIHLK 823
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000033582.1 (SMESG000033582.1) HSP 1 Score: 374.785 bits (961), Expect = 2.182e-113 Identity = 237/699 (33.91%), Postives = 385/699 (55.08%), Query Frame = 3
Query: 432 NDNSPTFPEKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFVDNKQPILIVKHQIDREFIDRIEFTLIAVDGGKPPRKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHGVALKLISKLDYETINKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYG-IVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDM-KNYFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIK--TSTNENIYPENCVTFPYIFVDLDEGENSKVRVTMKNNDYFSLTPDYGMLCAMEKLPPIGDYKTVIVAEDGD-FNNSRKQEFLINIHIK 2513
NDN P FP+ + EN +I + LP A D D +G++SY++ +++ F++ E DN+ +L+ K +IDRE ++A+D GKP + G IIL+V D ND P F + + ++E+ +G E+ ++V D D G N ++S N T+Q Q F+L Q G++L+L S LDYE N + F ++AKD G P STA V V VTN+ND PP I+FY + ++ + E K I L+ VTD D++ I CE+ ++ FYL + ++E +K +E+++ I+FDRET +++ ++I CSD+ I++L Q+ ++++ I D+NDN P+FSS ++G I++ + ++ V + + I TD D G N ++Y++ + ++ YFS++ +K +DYEK K + A D G P ++S ++ ++V D NDN+PE+ FY+F + E +PIGT +G++ +D DTD + I +L Q + +F I+N +G I T+VVLD E + F + N N KD + + +++TV I+D NDNSP + LK+ V+ +S K T +I C FPY F+D DEG N++V VT+K N FSL + ++C G + ++ +D + N SR+ E LINIH+K
Sbjct: 23 NDNEPIFPQSYIKIAVHENVEIGHTLVLPKAEDLDTPSYGIDSYKLIS-DKSCGSCFEVKNEP-KDNRL-VLVFKTKIDRETNSVFNLLVLAIDRGKPSKTGSLSIILEVEDINDNRPHFEESTISLSVEENGRSGREIKRIKVTDSDIGANSQMSYNIEDYTSQ-AQRYFKLFQIKDGISLQLQSTLDYENKNIFEFRIIAKDQGTPYLMSTATVTVRVTNLNDEPPEILFYNRGSIVDPNSIQLTLPENGPKHQTIILIHVTDKDSKLSDILCEVSHPKDVFYLRETENVNIIEKKKIFELQNLIEFDRETTSIYRITITCSDSNTISKLTQSVEIQMKIDDVNDNPPIFSSSFHFGKIMETDLTDQDVHMTEGVIQVTDADIGMNSRIKYHLKDALNSTDSQYFSVNSEYPQIKNKEPIDYEKSKQFKFFLVAVDGGKPALTASTQITISVSDANDNRPEIGNKFYTFSVLEEQPIGTKIGQIVASDADTD---QLNRDVIFEMLSLDGTKRRQRQNDLFIIENNTGFIKTRVVLDHEKDQHVSFLVRVRNTNEYVGTKDKLDFYSSS--VAITVKIIDINDNSPKLALKESLIVEQAGSCLSSQKPIIITTSDIASNLCSEFPYTFLDADEGLNAEVVVTLKENPNFSLDMGHNLICLKNLHLSPGYFTVNVIGQDRNGGNGSRRAECLINIHLK 712
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000048159.1 (SMESG000048159.1) HSP 1 Score: 274.633 bits (701), Expect = 1.290e-76 Identity = 271/883 (30.69%), Postives = 412/883 (46.66%), Query Frame = 3
Query: 78 FFCQLSELDACDSIKQVEITETTVSLFELADVSDHIGRSGLKSDSFY--------LSEDTDSFQL-INGRVTLRRPIDREEYCSKSNKHQTYINSQCCGGQCCLFIGIASNDNTX-XXXXXXXXXXXXNDNSPTFPE-KTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLMTEDFV-----DNK-QPILIVKHQIDREFIDRIEFTLIAVDGGKPP--RKGKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLSQTLHG-VALKLISKLDYET-INKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETKTLHF--VSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKNY-----FSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVRSSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTMEISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEG--ENSKVRVTMKNNDY---FSL---TPDYGMLCAMEKLPPIGDYKTVIVAEDGDFN--NSRKQEFLINIHIKEDPHTLNNKIRTSQ-GNHESKYNSEYPARSNER 2609
FF LSE+ +K + ITE +S+ LA++++ + SF L D F+L +N + ++RE C + + + C CC IG T +I IK++D ND +P F K + +I EN ++ I LPMA D+D + V Y + +Y T DF DN +P LIV ++D E I++ F L A D + T I +++ D ND P+F+QL Y I E++ +L+ V D DSG NG +++N T++ + F++ + L+LI+ LDYET + + F L+A D G P SS+A V++ + N+ND+ P I F + +S + I EG ++ V+VTD D ++ I C++ + FYL++ L N K + +K+ DRE+ F ++I C+D+E Q+ L + I+D+NDNAP+FS Y G V EN+VN +V K PI+ TD+D G NG E+Y+ +D +N+ F IDK +G + T LDYE +I A D G +SS + +NV D NDN P S Y F ++EN +G +G + TD DTD NK I ++ F ID +G + T+ LDRE I + A NPN Y R E+ V + ++D NDN+P + P++ + +V FI + + C PY D+D+G T+ NDY FSL TP Y +C K Y ++A D N + + I DPH+ KI TS NH +S +P S +
Sbjct: 14 FFQVLSEV-----LKTITITENDMSIQVLANLTEILASKTNLPHSFLSKVEIVSLLENDLPPFKLQLNQLIQPNNGVNREAVCRDNPGEK--VRKFCKADLCCKLIGFQYLTPTDPGTFFILIKILDQNDKAPQFSSIKRPFFKIPENVEVGKVIDLPMAVDSDSEKYSVRRYSLSY------IYHLDQTHDFRLHVTNDNPPRPQLIVNSKLDYEKINKYVFRLFAYDFDEKSIGNSCSTTIEIEIEDLNDNVPKFNQLTYNANIDENKRDD-KLIKFTVSDPDSGRNGIVTVNIVDKTDE-LSKRFKIFEIQRNEFFLELINSLDYETDPHLFEFTLLATDQGTPSLSSSAQVKIHLKNLNDNGPKIKFKKLGFSVSNSVSII---EGLPAHSLVVEVRVTDADTHSNMIHCKLVDYNDLFYLDSPSKFNTLLNYKPFNLKTINKIDRESNHGSFLRITISCTDSEPSRQITTNESLNIQIEDVNDNAPMFSQQIYIGNVDENQVNVVVNFPK-PIIVTDRDSGLNGKFEFYL----EDFRNFSDSSDFLIDKISGKIFTQRSLDYETKNKFRFKIIAIDKGYQPLTSSSTITINVLDLNDNAPRFSESHYIFNVFENVSVGWKIGTLQATDDDTDRKNKDIFY---------SIEPKGDHSSYFDIDRYTGDLRTRKPLDRETLESISIKVTAKNPN--KYSSHFVRN--TDSEVDVMIKVMDVNDNAPKFI----PRLN-MKQKVEFI---VEQFVDGNTCTELPYTVQDIDDGGINGQNCCYTILENDYNKLFSLMTDTPSY--ICLQRKPEKYQSYTVTLIARDRPPNVEGGLTSKISFPVLIINDPHS---KISTSGFSNHP---DSRFPNPSESK 844
BLAST of Protocadherin-1 vs. Planmine SMEST
Match: SMESG000053174.1 (SMESG000053174.1) HSP 1 Score: 267.314 bits (682), Expect = 1.385e-74 Identity = 244/791 (30.85%), Postives = 380/791 (48.04%), Query Frame = 3
Query: 261 VTLRRPIDREEYCSKSNKHQTYINSQCCGG--QCC--LFIGIASNDNTXXXXXXXXXXXXXNDNSPTFP-EKTYYKEILENSKINSRISLPMAYDADDLPFGVESYEIEKPNENFDVYFKLM-TEDFVDNKQ-----PILIVKHQIDREFIDRIEFTLIAVDGGKPPRK-GKTKIILKVLDENDCEPQFSQLIYEIKIKESEMTGLELLHLRVEDKDSGNNGKISINFASSTNQDIQNTFQLS---QTLHGVA--LKLISKLDYETI-NKYSFNLVAKDFGQPPRSSTALVEVFVTNVNDSPPNIVFYQFNKPISKQYARIYINEGTTKDMVICLVKVTDDDNQADSITCEIETSQESFYLNALKTNAVLENRKTYEIKSKIDFDRETK------TLHFVSIVCSDTEGINQLKQTNKLEVIIKDINDNAPVFSSPRYYGIVKENRVNEIVTINKDPILATDKDEGENGTVEYYISNVVDDMKN-----YFSIDKNTGVVKTILGLDYEKIKHVSIEISAKDLGVPVR-SSSVKLIVNVKDTNDNQPEVDLSFYSFELYENEPIGTYVGKVNVTDKDTDXXXXXXXXXXXXLLPGPTLGTSQPADQIFTIDNESGKIYTKVVLDREMSSQIPFAIIASNPNPLDYGKDLFRQFRDTM-EISVTVNILDKNDNSPMMMLKDKPQVKAVNPEVSFIKTSTNENIYPENCVTFPYIFVDLDEGENSK----VRVTMKNNDYFSLTPDYGMLCAMEKLP-PIGDYKTVIVAEDGDFNNSRKQEFLINIHIKEDPH 2525
+ + + IDREE C Q ++ CG CC L I+ N+ + +I++ V D NDN+P FP +T Y I EN + RI LP A D D+ F V SY++E P FKL + DF K P LI+ +DRE FTLIA+DG + R GKT+I +K+ D ND P+F + IY IKE+ + + + V D+D NG+I + +S + I F L Q++ V ++ I+ LDYE + + + F +VA+D G+ SSTA + + + NVND P I F + + I+ ++ I+EGT + ++ V+V+D D+ + + C + T + + + + K + +++ + DRE + V++ C D + L + +II D+NDN P F+ YYG ++EN N V +N I A DKD NG V Y+I D KN YF ID G + D+EK S + A D G P R SSS +IV +KD NDN P+ S ++F + EN IG +G++N TD+D+ +K I +K+ + A ++ T+D +G+I T+ +DRE +S I F + + NP+ R F D + E + + + D ND+ P LKD P S + S + C + P+ D D+ N VR+ N SL D + + ++P + ++A D N+S + E I DP+
Sbjct: 18 LKVSKQIDREELCPPQMMLQL---NKVCGSIHTCCHILDFQISCNNEEMQSNFIRVFVDDENDNNPVFPIVQTPYCTIEENKPLGYRIPLPKAQDLDNATFSVSSYKLELP-------FKLGNSSDFELAKHFKDGVPYLIITSTLDREKTSMYTFTLIAIDGVEGNRNTGKTEITIKIRDINDNAPKFERPIYIRTIKENVIVD-PIFQILVTDEDEDENGRIDLKMHNSGQEWINKIFTLDILDQSIGKVQAQVRAINNLDYEQLYHSFEFKIVAQDGGRNSLSSTATLRIQILNVNDMSPEIRFVRNGQQITGGFS---IDEGTLSNKILAYVQVSDADSMINQLQCSLLTPRNILMIEESRFRHPVNIYKQFSLRTTQNIDREANEPFLIDSKIIVTVQCDDYDNEIPLNTNASIFIIINDVNDNPPKFTQNVYYGQIEENINNHEVFMNA-AIHAADKDLHLNGKVTYHIQ----DFKNSSNAMYFRIDSQNGKIYNSQSFDFEKESIYSFIVVATDQGHPNRLSSSSTIIVRIKDQNDNAPQFSQSHFAFFVDENVEIGHLIGQINATDRDSLPEHKDIRFIVKS-------DSQNRASKLITLDPLTGQIRTRYPIDREKTSTITFFVESKNPS---------RIFNDLIQEAMIVITVRDLNDSPPTFRLKD--------PSKSQLIISLETLQQGQICESIPFEVEDADDNNNVNPCCVVRLKHNYNGLLSLADDTQNIICINQVPKKVKSLPVTLIASDKHGNDSIETEITFKILFINDPN 765 The following BLAST results are available for this feature:
BLAST of Protocadherin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031442 ID=SMED30031442|Name=Protocadherin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3218bpback to top protein sequence of SMED30031442-orf-1 >SMED30031442-orf-1 ID=SMED30031442-orf-1|Name=SMED30031442-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1017bp MEIILLILIFFCQLSELDACDSIKQVEITETTVSLFELADVSDHIGRSGLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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