Junctophilin

Overview
NameJunctophilin
Smed IDSMED30031366
Length (bp)3422
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Junctophilin (SMED30031366) t-SNE clustered cells

Violin plots show distribution of expression levels for Junctophilin (SMED30031366) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Junctophilin (SMED30031366) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Junctophilin (SMED30031366) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30031366

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30031366h1SMcG0004613 Contig45390uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30031366h1SMcG0004613 Contig45390newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30031366h1SMcG0004613 dd_Smed_v4_6259_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30031366h1SMcG0004613 dd_Smed_v4_6259_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30031366h1SMcG0004613 dd_Smed_v4_6259_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30031366h1SMcG0004613 dd_Smed_v4_6259_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30031366h1SMcG0004613 dd_Smed_v6_6259_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Junctophilin vs. Ensembl Human
Match: JPH3 (junctophilin 3 [Source:HGNC Symbol;Acc:HGNC:14203])

HSP 1 Score: 203.756 bits (517), Expect = 6.244e-54
Identity = 147/445 (33.03%), Postives = 230/445 (51.69%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQ 1690
             GR+ F D G Y G W + KA G G+ T  K QGE+TG W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  K+EG + +G    +G ETY+DGGTY G +  G+R+G GVR S+PYG + A +   +  L  S     S + + T+ H D + + +  P   + GFVL       ++K  +     +    GLK  +S+S +S+ S  +K+  +      ++  G  +V S   +      HS+++    ++ +A ++    D I     ETY GEW  D+R GFGV +RSDG+ YEG W +N+RHG+G   F DG+ EEG+Y+    I +  KR  +  L + ++   + ++V+ A  A+  A++K      + +  R   + A  AA  A+E +   R   KE  P ++ 
Sbjct:    4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVI---RSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN--ILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQH 425          
BLAST of Junctophilin vs. Ensembl Human
Match: JPH2 (junctophilin 2 [Source:HGNC Symbol;Acc:HGNC:14202])

HSP 1 Score: 197.593 bits (501), Expect = 3.815e-52
Identity = 153/463 (33.05%), Postives = 224/463 (48.38%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYG-EIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIV 1720
             GR++F D G Y G W   KA G GL T  K QGE++G WN G E  GV+ WPS  G  +EG W+  KR G GI  K  W+  G++  GF    G++    S  K+EG + +G    +G ETYADGGTY G + +G+R G GVR S+PYG  +    P    L    +   N T    +      +G A   P   + GF LS   +     +          Q+G     L+R++S TS+ S  ++     +               +   AS  +  +SL      +       A   I     ETY GEW  D+R GFGV ERS G+ YEG WL+N RHG+G T   DG  EEG+Y++  L+    +R  +  L S ++   ++ SV+ A+ A+  A++K      + +  +   + A++AA  A + S   R L +E+ PD+ QPG      R+L +I+
Sbjct:    3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGL--FQRGALLGKLRRAESRTSVGSQRSRVSFLKS--------------DLSSGASDAASTASLGEAAEGADEAAPFEA--DIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRR--MLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEIL 443          
BLAST of Junctophilin vs. Ensembl Human
Match: JPH1 (junctophilin 1 [Source:HGNC Symbol;Acc:HGNC:14201])

HSP 1 Score: 192.2 bits (487), Expect = 1.402e-50
Identity = 145/451 (32.15%), Postives = 212/451 (47.01%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINA--CKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W   KA G G+ T  K QGE++G W+ G E  G + WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  ++EG + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S        H     + S  P   + GFVL+            H +A    K + GL R  SL         +   +  +   +     ++  +          SS   N+  S   +D       D +     ETY GEW  D+R+GFGV ERS+G+ YEG W NNKRHG+G T F DGS EEG+Y+N   I +   R  +  +   +    + ++++ A+ A+  A+ K      +    R     A +AA  AR+     R + +E+ PD+ QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPS--GNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQSNGSVL---HDAAAAADS--PAGTRGGFVLN-----------FHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRI----------SSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN--ILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG 420          
BLAST of Junctophilin vs. Ensembl Human
Match: JPH4 (junctophilin 4 [Source:HGNC Symbol;Acc:HGNC:20156])

HSP 1 Score: 179.489 bits (454), Expect = 1.593e-46
Identity = 130/451 (28.82%), Postives = 209/451 (46.34%), Query Frame = 2
Query:  368 PAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPI-FFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTD 1714
            P G+++F D G Y+G W   +A G G+ T   +QGE++G W  G E  GVF  P   G  Y+G W   KR+G G+  K  W   G++  G        +  S  ++ G ++DG    +G ETY+DGGTY G +++G R G GVR S+PY +  A L   +   L S   +  T         D+ GS +   +  + GFVL+G          +   A        +RS  L+ + +   +  L + +   ++   +    + P  +      ++     I+  AT              E Y+GEW  D+R GFGV +RS+G+ YEG WL N+RHG+G T   DGS EEG+Y+  +L+     R+ +   L   ++   + ++V+ AR A   A+++      +  +       A   A  A E +   + + +++ P  E PG R   D
Sbjct:    3 PGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPG--GHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQA-ALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSPA---SGSRGGFVLAGPGDADGASSRKRTPAAGGF---FRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSAT--------------EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQD 430          
BLAST of Junctophilin vs. Ensembl Human
Match: JPH4 (junctophilin 4 [Source:HGNC Symbol;Acc:HGNC:20156])

HSP 1 Score: 179.489 bits (454), Expect = 1.593e-46
Identity = 130/451 (28.82%), Postives = 209/451 (46.34%), Query Frame = 2
Query:  368 PAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPI-FFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTD 1714
            P G+++F D G Y+G W   +A G G+ T   +QGE++G W  G E  GVF  P   G  Y+G W   KR+G G+  K  W   G++  G        +  S  ++ G ++DG    +G ETY+DGGTY G +++G R G GVR S+PY +  A L   +   L S   +  T         D+ GS +   +  + GFVL+G          +   A        +RS  L+ + +   +  L + +   ++   +    + P  +      ++     I+  AT              E Y+GEW  D+R GFGV +RS+G+ YEG WL N+RHG+G T   DGS EEG+Y+  +L+     R+ +   L   ++   + ++V+ AR A   A+++      +  +       A   A  A E +   + + +++ P  E PG R   D
Sbjct:    3 PGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPG--GHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQA-ALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSPA---SGSRGGFVLAGPGDADGASSRKRTPAAGGF---FRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSAT--------------EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQD 430          
BLAST of Junctophilin vs. Ensembl Celegans
Match: jph-1 (JunctoPHilin [Source:UniProtKB/TrEMBL;Acc:Q22667])

HSP 1 Score: 212.231 bits (539), Expect = 3.660e-57
Identity = 161/530 (30.38%), Postives = 256/530 (48.30%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK----FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIA--TMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRIL-----------TDI------VRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL-TVNYNKDNFL 1867
            +  GR++F D G Y+G W   KA G G+ T  +++GE+ G W+ G E  GV+ WPS  G  Y+G+W N KR G GI  +  W+  G++ +G+    GV+    S  +++G     F DG   +G E Y D G+Y G +  G+R G G+R S  Y         EK    +S +  +++  S  S  V++  +A +  +K     + GFVL    S       R   +  +    +KR+     + S L  K+ ++T +IH+       V S+ G  S +S  S+++  +  S+    +     + +     ETY GEW  D R GFGVCERSDG+ Y+G W NN + G+G+T F DG+ EEG+Y+N  LI   ++R  + F+ + +    +++++  A  A+  AQ+K      + +  RE  ++A   A  A + S   R   K+  P ++QPG R L           TD+       R +  T   Q SFE  L  ++D+ E    P     N  +   N N  NF+
Sbjct:    1 MNGGRFDFDDGGTYVGGWEEGKAHGHGVCTGPQAKGEYAGAWHYGFEVSGVYTWPS--GNTYQGQWQNGKRHGLGIEQRGRWLYKGEWTQGYKGRYGVRQSANSQARYQGTWSAGFHDG---YGTEIYVDSGSYQGQWLRGMRHGYGIRKSTTY---------EKAAKFRSKSQTHASLTSLRSGRVEEENAAEEHRHKEGLSGRGGFVLRANSS----APQRRRRSLSERSLAVKRT-----LLSGLRIKKQHSTGDIHQR------VASMTG--SLRSSGSTMSCTSEDSLHHHGLQQPEEEAVEESSIETYMGEWKNDMRSGFGVCERSDGLKYQGEWANNAKCGYGVTTFKDGTKEEGRYKNNILIAS-SRRKGVIFMRASKFREKLEQALGAASRAASIAQQKADIAASRTSTARERSEQASFIARQANDDSEVARIHAKQFDPSFKQPGTRRLLKDNNGGESFGTDLSDAISYSRHLSQTHSKQHSFEQTL--SVDMAEDMTPPSKAYHNHVMPNSNTNHVNFM 496          
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0079861)

HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54
Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561
             GR++F+D G Y G W   KA G G+ T  K QG + G WN G E  G ++WPS  G+ YEG+W N +R G G+      I  G++ ++G     GV+    S  K+EG     ++DG    G ETYADGG Y G ++ G R G G+RTS P+G             L S     + + S +S    +NG+A+K+  K    + GFVL+ K   L ++  R+    K  +KG             L  ++  +T ++ K   GTI+  S+    S  S+       S+LT   N  +S A+  M   + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N  LI    K++ +F   S ++   I  ++  A+ A K A Q  DM
Sbjct:   49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430          
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0079860)

HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54
Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561
             GR++F+D G Y G W   KA G G+ T  K QG + G WN G E  G ++WPS  G+ YEG+W N +R G G+      I  G++ ++G     GV+    S  K+EG     ++DG    G ETYADGG Y G ++ G R G G+RTS P+G             L S     + + S +S    +NG+A+K+  K    + GFVL+ K   L ++  R+    K  +KG             L  ++  +T ++ K   GTI+  S+    S  S+       S+LT   N  +S A+  M   + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N  LI    K++ +F   S ++   I  ++  A+ A K A Q  DM
Sbjct:   49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430          
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0304056)

HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54
Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561
             GR++F+D G Y G W   KA G G+ T  K QG + G WN G E  G ++WPS  G+ YEG+W N +R G G+      I  G++ ++G     GV+    S  K+EG     ++DG    G ETYADGG Y G ++ G R G G+RTS P+G             L S     + + S +S    +NG+A+K+  K    + GFVL+ K   L ++  R+    K  +KG             L  ++  +T ++ K   GTI+  S+    S  S+       S+LT   N  +S A+  M   + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N  LI    K++ +F   S ++   I  ++  A+ A K A Q  DM
Sbjct:   49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430          
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0304057)

HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54
Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561
             GR++F+D G Y G W   KA G G+ T  K QG + G WN G E  G ++WPS  G+ YEG+W N +R G G+      I  G++ ++G     GV+    S  K+EG     ++DG    G ETYADGG Y G ++ G R G G+RTS P+G             L S     + + S +S    +NG+A+K+  K    + GFVL+ K   L ++  R+    K  +KG             L  ++  +T ++ K   GTI+  S+    S  S+       S+LT   N  +S A+  M   + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N  LI    K++ +F   S ++   I  ++  A+ A K A Q  DM
Sbjct:   49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430          
BLAST of Junctophilin vs. Ensembl Fly
Match: CG30429 (gene:FBgn0050429 transcript:FBtr0072450)

HSP 1 Score: 52.373 bits (124), Expect = 1.142e-6
Identity = 24/63 (38.10%), Postives = 40/63 (63.49%), Query Frame = 2
Query: 1268 TYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQ----YQNGKLIF 1444
             Y G+W++++RHG G+   +DG IY G W  + RHG G+  +++G+  EG     Y+NG+ +F
Sbjct:  118 VYFGKWIKNRRHGLGIQWYNDGNIYAGEWETDFRHGLGVMFYANGNRYEGHFARGYKNGEGVF 180          

HSP 2 Score: 51.2174 bits (121), Expect = 2.760e-6
Identity = 27/83 (32.53%), Postives = 41/83 (49.40%), Query Frame = 2
Query: 1178 FHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQ 1426
            +      N  Q + +M    G     +V   YSG W  D + G G    SDG +Y G W+ N+RHG GI  ++DG+   G+++
Sbjct:   69 YEGDWVMNKRQGVGSMLRKRGT----EVQLIYSGRWYDDMKCGEGKQFYSDGCVYFGKWIKNRRHGLGIQWYNDGNIYAGEWE 147          
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph1b (junctophilin 1b [Source:ZFIN;Acc:ZDB-GENE-060616-389])

HSP 1 Score: 209.534 bits (532), Expect = 1.810e-56
Identity = 146/446 (32.74%), Postives = 229/446 (51.35%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G + G W + KA G G+ T  K QGE++G W++G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  ++EG + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S N S   +H+      S  P   + GFVL+      ++            +KGL R  SL   F +L +    ++++   +   +    +     S    +S+++F   + +A   M A D +     E+Y GEW  D+R+GFGV ERS+G+ YEG W+NNKRHG+G T F DG+ EEG+Y+N  L+    K+  +  L + +    + ++V+ A  AS  A+ K      +    R   + A +A+  A + S   R + +++ P++ QPG
Sbjct:    1 MTGGRFDFDDGGTFCGGWEDGKAHGHGICTGPKGQGEYSGSWSNGFEVVGVYTWPS--GNTYKGYWAQGKRHGLGVESKGRWLYRGEWSHGFKGRYGVRQSLNTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQS-NGSVLHDHM------SDSPAGTRGGFVLNFHSDSEVVSG---------KKKGLFRRGSL---FGSLKQLRKSDSRSSISSKRSSARSDATMSRISSSDANSTISFGDGE-VADEYMPAEDNVDATTTESYLGEWKNDKRNGFGVSERSNGMKYEGEWINNKRHGYGCTMFPDGTKEEGKYKNNVLVRGIKKQ--LIPLKNTKTKQKVDRAVEGAIRASAIARTKVEIATSRTAHARAKAEAADQASLSASQESDLARAVARDLSPNFHQPG 421          
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph1b (junctophilin 1b [Source:ZFIN;Acc:ZDB-GENE-060616-389])

HSP 1 Score: 209.534 bits (532), Expect = 1.810e-56
Identity = 146/446 (32.74%), Postives = 229/446 (51.35%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G + G W + KA G G+ T  K QGE++G W++G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  ++EG + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S N S   +H+      S  P   + GFVL+      ++            +KGL R  SL   F +L +    ++++   +   +    +     S    +S+++F   + +A   M A D +     E+Y GEW  D+R+GFGV ERS+G+ YEG W+NNKRHG+G T F DG+ EEG+Y+N  L+    K+  +  L + +    + ++V+ A  AS  A+ K      +    R   + A +A+  A + S   R + +++ P++ QPG
Sbjct:    1 MTGGRFDFDDGGTFCGGWEDGKAHGHGICTGPKGQGEYSGSWSNGFEVVGVYTWPS--GNTYKGYWAQGKRHGLGVESKGRWLYRGEWSHGFKGRYGVRQSLNTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQS-NGSVLHDHM------SDSPAGTRGGFVLNFHSDSEVVSG---------KKKGLFRRGSL---FGSLKQLRKSDSRSSISSKRSSARSDATMSRISSSDANSTISFGDGE-VADEYMPAEDNVDATTTESYLGEWKNDKRNGFGVSERSNGMKYEGEWINNKRHGYGCTMFPDGTKEEGKYKNNVLVRGIKKQ--LIPLKNTKTKQKVDRAVEGAIRASAIARTKVEIATSRTAHARAKAEAADQASLSASQESDLARAVARDLSPNFHQPG 421          
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph1a (junctophilin 1a [Source:ZFIN;Acc:ZDB-GENE-040724-233])

HSP 1 Score: 202.601 bits (514), Expect = 3.968e-54
Identity = 148/469 (31.56%), Postives = 222/469 (47.33%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNL-SFTSNHVDKNGSASKLPNKFKCGFVL---------SGKKSDL-----LIKKLRHINACKKHQKGLKRSKSLTSIFS----ALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRIL 1708
            +  GR++F D G Y G W + KA G G+ T  K QGE++G W+ G E  GV+ WPS  G  Y+G W+  KR G G+  K  W+  G++  GF    GV+    +  +++G + +G    +G+ETY D GTY G +  G+R G GVR S+PYG            +++S    +  +L S  SN      +    P   + GFVL         +GKK  L     L   LR           L++S S TSI S    A +   +    +   N   +     VP + +P   H   T                       E+Y GEW  D+R+GFGV ERS+G+ YEG W+NNKRHG+G T F DG+ EEG+Y+N  L+     R  +  L + +    + ++V+ AR ++  A+ K      + +  R   + A +AA  A + S   R +  E+ P + QPG+  +
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPS--GNTYQGYWSQGKRHGLGVETKGKWLYRGEWSHGFKGRYGVRQSTNTPARYDGTWSNGLQDGYGVETYGDSGTYQGQWMGGMRHGYGVRQSVPYGMA---------TIIRSPLRTSLASLRSVQSNGAVLQDTVPDTPVGSRGGFVLNFHSDTEVVTGKKKGLFRRGSLFGSLRQ----------LRKSDSKTSISSKRSSARSDATMSRISSSDANSTISYGEGEVPDDYTPMEDHVDAT---------------------TTESYMGEWKNDKRNGFGVSERSNGLKYEGEWMNNKRHGYGCTIFPDGTKEEGKYKNNVLVR--GIRKQLIPLKNHKTKEKVDRAVEGARRSAAIARTKVEIAVSRTSHARTKSEAADQAALAACQESDLARAVACELSPSFHQPGLEYI 425          
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph3 (junctophilin 3 [Source:ZFIN;Acc:ZDB-GENE-060503-415])

HSP 1 Score: 202.601 bits (514), Expect = 1.688e-53
Identity = 144/455 (31.65%), Postives = 213/455 (46.81%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSN-------HVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDT-IAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRI 1705
             GR+ F D G Y G W   KA G G+ T  K QGE+ G W+ G E  G++ WPS  G  ++G WA  KR G GI  K  W+  G++  GF    GV+    + GK+EG + +G    +G ETY+DGGTY G +  G+R G GVR S+PYG + A +       + S   E+S   +  +                   P   + GFVL+      L+K  +         KGL R     S+ S L  ++  +  ++        S  S  G ++  S  S +           ++  GD  +     E+Y+GEW  D+R G GV  RSDG+ Y+G WL NKRHG+G T F DG+ EEG+Y+    I +  KR  +  L + ++   + ++V+ A  A+  A++K      +    R     A  AA  A+E     R   KE  P ++  G R+
Sbjct:    4 GGRFNFDDGGSYCGGWEEGKAHGHGICTGPKGQGEYAGSWSHGFEVVGIYTWPS--GNTFQGTWAQGKRHGIGIENKGKWVYKGEWTHGFKGRYGVRESTGTSGKYEGTWNNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHSNGTALLTGDRAPVAGVGGSGVLVVGSPAVSRGGFVLTAHSEAELLKNKK---------KGLFRR----SLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGEGELPVGDDDVDATTTESYAGEWKNDKRTGCGVSRRSDGLQYQGEWLGNKRHGYGCTTFPDGTKEEGKYKQN--ILVSGKRKNLIPLRASKIREKVDRAVESADKAADIAKQKAEIALSRTAHARGKADAATAAAQKAQEECRLARITAKEFSPSFQHRGNRV 440          
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph2 (junctophilin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-9848])

HSP 1 Score: 202.216 bits (513), Expect = 2.473e-53
Identity = 146/458 (31.88%), Postives = 217/458 (47.38%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGL----------KRSKSLTSIFSALTKKELYNTKNIHKNHFG----TISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
             GR+EF D G Y G W   KA G G+ T  K QGEF+G WN G E  GV+ WPS  G  YEG W+  KR G G+  K  WI  G++  GF    G +  + S  K+EG + +G    +G ETYADGGT+ G +  G+R G GVR S+PYG         ++ L    ++ ++  L      V    +AS           L   +    +      +A K  + GL          K+S S TS+ S  +K     T++   +       TIS+         +       F  +++    D+ A  T      E Y GEW  D+R G+G+ ERS G+ YEG WLNN+RHG+G T F +G  EEG+Y N  L+    K+  +  L   ++   +++S++ A+ A+  A++K      +    +     A++AA  A   S   R + +E+ P + QPG
Sbjct:    3 GGRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEFSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVETKGHWIYKGEWTHGFKGRYGTRISQGSGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYGMAAVVHSPLRNSLSSLRSEHSNGTLLQQDVPVITTTNASGQETPVNLPMPLGPSRGGFALTLQVDPDAVKPKKSGLFRRGSFLGKLKKSDSRTSLSSQKSKISFLRTESALSSAASDANSTISLGES------EGEGEGHNFPPVEA----DIDATTT------EVYMGEWKNDKRSGYGISERSSGLKYEGEWLNNQRHGYGCTTFPEGGKEEGKYVNNMLVKSVKKK--MIQLKGTKIKQKVERSLEGAQRAAAIAKQKAEIANSRTAHAKSKGDAAEQAAVAANNESSIARVVARELSPSFHQPG 440          
BLAST of Junctophilin vs. Ensembl Xenopus
Match: JPH3 (junctophilin 3 [Source:NCBI gene;Acc:105947054])

HSP 1 Score: 208.379 bits (529), Expect = 2.339e-55
Identity = 148/445 (33.26%), Postives = 218/445 (48.99%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINA--CKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSA-GDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQ 1690
             GR+ F D G Y G W + KA G G+ T  K QGE+ G W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  K+EG + +G    +G ETY+DGGTY G + +G+R G GVR S+PYG + A +   +  L  S     S + + T+ H D + + S  P   + GFVL           + H +A   K  +KG+ R     SI S L  ++  +  ++        S  S  G ++  S  S +           ++S   D I     E Y GEW  D+R GFGV +RSDG+ YEG W NNKRHG+G   F DG+ EEG+Y++  L+    KR  +  L + ++   + ++V +A      A++K      + +  R     A  AA  A+E +   R   KE  P ++ 
Sbjct:    4 GGRFNFDDGGSYCGGWQDGKAHGHGICTGPKGQGEYAGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGLGVESKGKWVYRGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWAAGIRHGYGVRQSVPYG-MAAVI---RSPLRTSINSLRSEHTNGTALHPDASCTVSGSPAVSRGGFVL-----------MAHSDAEILKNKKKGIFRR----SILSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDINSTISLGEGETELSVIEDDIDATTTEVYMGEWKHDKRSGFGVSQRSDGLKYEGEWANNKRHGYGCMTFPDGTKEEGKYKHNVLVS--GKRKNLIPLRASKIREKVDRAVDEAERVCNIAKQKAEIAASRTSHSRAKADAAATAALKAQEEAQIARISAKEFSPSFQH 425          
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849])

HSP 1 Score: 202.216 bits (513), Expect = 9.145e-55
Identity = 144/450 (32.00%), Postives = 212/450 (47.11%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W + KA G G+ T  K QGE++G W+ G E  G + WPS  G  Y G WA  KR G G+  K  WI  G++  GF    GV+    +  +++G + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S         VD        P   + GFVL+    S+L+  K          +KGL R  SL             +  +   +     ++  +          SS   N+  S    D       D +     ETY GEW  D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N  L+     R  +  + + +    + ++++ A+ A+  A+ K      +    R     A +A+  AR+ S   R + +E+ P + QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVR--GIRKQLIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418          
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849])

HSP 1 Score: 203.756 bits (517), Expect = 1.595e-54
Identity = 144/450 (32.00%), Postives = 213/450 (47.33%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W + KA G G+ T  K QGE++G W+ G E  G + WPS  G  Y G WA  KR G G+  K  WI  G++  GF    GV+    +  +++G + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S         VD        P   + GFVL+    S+L+  K          +KGL R  SL             +  +   +     ++  +          SS   N+  S    D       D +     ETY GEW  D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N  L+    K+  +  + + +    + ++++ A+ A+  A+ K      +    R     A +A+  AR+ S   R + +E+ P + QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVRGIRKQ--LIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418          
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849])

HSP 1 Score: 201.83 bits (512), Expect = 1.647e-54
Identity = 144/450 (32.00%), Postives = 212/450 (47.11%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W + KA G G+ T  K QGE++G W+ G E  G + WPS  G  Y G WA  KR G G+  K  WI  G++  GF    GV+    +  +++G + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S         VD        P   + GFVL+    S+L+  K          +KGL R  SL             +  +   +     ++  +          SS   N+  S    D       D +     ETY GEW  D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N  L+     R  +  + + +    + ++++ A+ A+  A+ K      +    R     A +A+  AR+ S   R + +E+ P + QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVR--GIRKQLIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418          
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849])

HSP 1 Score: 203.756 bits (517), Expect = 2.516e-54
Identity = 144/450 (32.00%), Postives = 213/450 (47.33%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W + KA G G+ T  K QGE++G W+ G E  G + WPS  G  Y G WA  KR G G+  K  WI  G++  GF    GV+    +  +++G + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S         VD        P   + GFVL+    S+L+  K          +KGL R  SL             +  +   +     ++  +          SS   N+  S    D       D +     ETY GEW  D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N  L+    K+  +  + + +    + ++++ A+ A+  A+ K      +    R     A +A+  AR+ S   R + +E+ P + QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVRGIRKQ--LIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418          
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph3 (junctophilin 3 [Source:MGI Symbol;Acc:MGI:1891497])

HSP 1 Score: 204.527 bits (519), Expect = 2.284e-54
Identity = 127/362 (35.08%), Postives = 193/362 (53.31%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441
             GR+ F D G Y G W + KA G G+ T  K QGE+TG W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  K+EG + +G    +G ETY+DGGTY G +  G+R+G GVR S+PYG + A +       + S   E++   +    H D + + +  P   + GFVL       ++K  +     +    GLK  +S+S +S+ S  +K+  +      ++  G  +V S   +      HS+++    ++ +A ++    D I     ETY GEW  D+R GFGV +RSDG+ YEG W++N+RHG+G   F DG+ EEG+Y+   L+
Sbjct:    4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHTNGAAL---HPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLV 344          
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph3 (junctophilin 3 [Source:MGI Symbol;Acc:MGI:1891497])

HSP 1 Score: 204.527 bits (519), Expect = 2.284e-54
Identity = 127/362 (35.08%), Postives = 193/362 (53.31%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441
             GR+ F D G Y G W + KA G G+ T  K QGE+TG W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  K+EG + +G    +G ETY+DGGTY G +  G+R+G GVR S+PYG + A +       + S   E++   +    H D + + +  P   + GFVL       ++K  +     +    GLK  +S+S +S+ S  +K+  +      ++  G  +V S   +      HS+++    ++ +A ++    D I     ETY GEW  D+R GFGV +RSDG+ YEG W++N+RHG+G   F DG+ EEG+Y+   L+
Sbjct:    4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHTNGAAL---HPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLV 344          
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph2 (junctophilin 2 [Source:MGI Symbol;Acc:MGI:1891496])

HSP 1 Score: 197.208 bits (500), Expect = 3.422e-52
Identity = 162/501 (32.34%), Postives = 239/501 (47.70%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL 1837
             GR++F D G Y G W   KA G GL T  K QGE++G WN G E  GV+ WPS  G  +EG W+  KR G GI  K  W+  G++  GF    G++    S  K+EG + +G    +G ETYADGGTY G + +G+R G GVR S+PYG +   +       L S   E+S N +   +    +G     P   + GF L+      L+             +G     L+RS+S TS+ S  ++     ++              +   AS  +   SL     +            I     ETY GEW  D+R GFGV ERS G+ YEG WL+N RHG+G T   DG  EEG+Y++  L+   TKR  +  L S ++   ++  V+ A+ A+  A++K      + +  +   + A++AA  A + S   R L KE+ PD+ QPG      R+L +I+          ++ ES+L+     + G G+PE    +  L
Sbjct:    3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYG-MAVVVRSPLRTSLSSLRSEHS-NGTVAPDSPAADGPMLPSPPVPRGGFALT------LLATAEAARPQGLFTRGTLLGRLRRSESRTSLGSQRSRLSFLKSE--------------LSSGASDAASTGSLA-EGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSSKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEIL----------ENSESLLEPPERGL-GTGLPERPRESPQL 465          
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph2 (junctophilin 2 [Source:MGI Symbol;Acc:MGI:1891496])

HSP 1 Score: 197.208 bits (500), Expect = 3.422e-52
Identity = 162/501 (32.34%), Postives = 239/501 (47.70%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL 1837
             GR++F D G Y G W   KA G GL T  K QGE++G WN G E  GV+ WPS  G  +EG W+  KR G GI  K  W+  G++  GF    G++    S  K+EG + +G    +G ETYADGGTY G + +G+R G GVR S+PYG +   +       L S   E+S N +   +    +G     P   + GF L+      L+             +G     L+RS+S TS+ S  ++     ++              +   AS  +   SL     +            I     ETY GEW  D+R GFGV ERS G+ YEG WL+N RHG+G T   DG  EEG+Y++  L+   TKR  +  L S ++   ++  V+ A+ A+  A++K      + +  +   + A++AA  A + S   R L KE+ PD+ QPG      R+L +I+          ++ ES+L+     + G G+PE    +  L
Sbjct:    3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYG-MAVVVRSPLRTSLSSLRSEHS-NGTVAPDSPAADGPMLPSPPVPRGGFALT------LLATAEAARPQGLFTRGTLLGRLRRSESRTSLGSQRSRLSFLKSE--------------LSSGASDAASTGSLA-EGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSSKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEIL----------ENSESLLEPPERGL-GTGLPERPRESPQL 465          
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph1 (junctophilin 1 [Source:MGI Symbol;Acc:MGI:1891495])

HSP 1 Score: 196.052 bits (497), Expect = 6.037e-52
Identity = 144/449 (32.07%), Postives = 211/449 (46.99%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W   KA G G+ T  K QGE++G W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  ++EG + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S              S    P   + GFVL+      L KK          + GL R  SL         +   +  +   +     ++  +          SS   N+  S   +D       D +     ETY GEW  D+R+GFG+ ERS+G+ YEG W NNKRHG+G T F DGS EEG+Y+N   I +   R  +  + + +    + ++++ A+ A+  A+ K      +    R     A +AA  AR+     R + +E+ PD+ QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPS--GNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADS----PAGTRGGFVLNFHADTELGKK----------KGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRI----------SSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN--ILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG 420          
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q9ET77|JPH3_MOUSE (Junctophilin-3 OS=Mus musculus OX=10090 GN=Jph3 PE=1 SV=1)

HSP 1 Score: 204.527 bits (519), Expect = 1.597e-53
Identity = 127/362 (35.08%), Postives = 193/362 (53.31%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441
             GR+ F D G Y G W + KA G G+ T  K QGE+TG W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  K+EG + +G    +G ETY+DGGTY G +  G+R+G GVR S+PYG + A +       + S   E++   +    H D + + +  P   + GFVL       ++K  +     +    GLK  +S+S +S+ S  +K+  +      ++  G  +V S   +      HS+++    ++ +A ++    D I     ETY GEW  D+R GFGV +RSDG+ YEG W++N+RHG+G   F DG+ EEG+Y+   L+
Sbjct:    4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHTNGAAL---HPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLV 344          
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q9GKY7|JPH2_RABIT (Junctophilin-2 OS=Oryctolagus cuniculus OX=9986 GN=JPH2 PE=2 SV=1)

HSP 1 Score: 203.371 bits (516), Expect = 2.055e-53
Identity = 158/479 (32.99%), Postives = 225/479 (46.97%), Query Frame = 2
Query:  374 GRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYG-EIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----------LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAG----DTIAP-------DVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIV 1720
            GR++F D G Y G W   KA G GL T  K QGE++G WN G E  GV+ WPS  G  +EG W+  KR G GI  K  W+  G++  GF    G +    S  K+EG + +G    +G ETYADGGTY G + +G+R G GVR S+PYG  +    P    L    +   N T    +      +G A   P   + GF LS          L +  A +  + G           L+R++S TS+ S  ++                                S L+     + +T  +  G    D  AP          ETY GEW  D+R GFGV ERS G+ YEG WL+N RHG+G T   DG  EEG+Y++  L+   TKR  +  L S ++   ++ SV+ A+ A+  A++K      + +  R   + A++AA  A + S   R L +E+ PD+ QPG      R+L +I+
Sbjct:    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGTRQSTSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPAADGPALPSPAIPRGGFALS---------LLANAEAARAPKGGGLFPRGALLGKLRRAESRTSVGSQRSRVSF---------------------------LKSDLSSGASDAASTASLGEGAEGADDAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAVSRTSHARAKAEAAEQAALAANQESNIARSLARELAPDFYQPGPEYQKRRLLQEIL 442          
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q8WXH2|JPH3_HUMAN (Junctophilin-3 OS=Homo sapiens OX=9606 GN=JPH3 PE=1 SV=2)

HSP 1 Score: 203.756 bits (517), Expect = 2.999e-53
Identity = 147/445 (33.03%), Postives = 230/445 (51.69%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQ 1690
             GR+ F D G Y G W + KA G G+ T  K QGE+TG W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  K+EG + +G    +G ETY+DGGTY G +  G+R+G GVR S+PYG + A +   +  L  S     S + + T+ H D + + +  P   + GFVL       ++K  +     +    GLK  +S+S +S+ S  +K+  +      ++  G  +V S   +      HS+++    ++ +A ++    D I     ETY GEW  D+R GFGV +RSDG+ YEG W +N+RHG+G   F DG+ EEG+Y+    I +  KR  +  L + ++   + ++V+ A  A+  A++K      + +  R   + A  AA  A+E +   R   KE  P ++ 
Sbjct:    4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVI---RSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN--ILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQH 425          
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q2PS20|JPH2_RAT (Junctophilin-2 OS=Rattus norvegicus OX=10116 GN=Jph2 PE=1 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 6.777e-53
Identity = 164/501 (32.73%), Postives = 240/501 (47.90%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL 1837
             GR++F D G Y G W   KA G GL T  K QGE++G WN G E  GV+ WPS  G  +EG W+  KR G GI  K  W+  G++  GF    G++    S  K+EG + +G    +G ETYADGGTY G + +G+R G GVR S+PYG +   +       L S   E+S N +   +    +G    LP   + GF LS      L+             +G     L+RS+S TS+ S  ++     ++              +   AS  +   SL     +            I     ETY GEW  D+R GFGV ERS G+ YEG WL+N RHG+G T   DG  EEG+Y++  L+   TKR  +  L S ++   ++  V+ A+ A+  A++K      + +  +   + A++AA  A + S   R L KE+ PD+ QPG      R+L +I+          ++ ES+L+   +   G G+PE    +  L
Sbjct:    3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYG-MAVVVRSPLRTSLSSLRSEHS-NGTVAPDSPAADGPTLPLPPVPRGGFALS------LLATAEAARPPGLFTRGALLGRLRRSESRTSLGSQRSRLSFLKSE--------------LSSGASDAASTGSLA-EGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSNKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEIL----------ENSESLLEPR-ERGPGTGLPERPRESPQL 465          
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q9BR39|JPH2_HUMAN (Junctophilin-2 OS=Homo sapiens OX=9606 GN=JPH2 PE=1 SV=2)

HSP 1 Score: 197.593 bits (501), Expect = 1.832e-51
Identity = 153/463 (33.05%), Postives = 224/463 (48.38%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYG-EIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIV 1720
             GR++F D G Y G W   KA G GL T  K QGE++G WN G E  GV+ WPS  G  +EG W+  KR G GI  K  W+  G++  GF    G++    S  K+EG + +G    +G ETYADGGTY G + +G+R G GVR S+PYG  +    P    L    +   N T    +      +G A   P   + GF LS   +     +          Q+G     L+R++S TS+ S  ++     +               +   AS  +  +SL      +       A   I     ETY GEW  D+R GFGV ERS G+ YEG WL+N RHG+G T   DG  EEG+Y++  L+    +R  +  L S ++   ++ SV+ A+ A+  A++K      + +  +   + A++AA  A + S   R L +E+ PD+ QPG      R+L +I+
Sbjct:    3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGL--FQRGALLGKLRRAESRTSVGSQRSRVSFLKS--------------DLSSGASDAASTASLGEAAEGADEAAPFEA--DIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRR--MLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEIL 443          
BLAST of Junctophilin vs. TrEMBL
Match: A0A183ALC7 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS7762 PE=4 SV=1)

HSP 1 Score: 486.878 bits (1252), Expect = 4.191e-155
Identity = 254/547 (46.44%), Postives = 356/547 (65.08%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLP----------------------------EEKHLL---------LKSATDEN---STNLSFTSNHVDKNGSAS--------------KLPNKFKCGFVLSGKKSDLLIKKLRHI--NACKKHQKGLK-----------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798
            LPAGRYEFKDSG+YIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWA+++R+G+G+F +EDW++MGKF E FI+LG+K KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+REGLGVRTSIPYGE+  F P                                LL         L++A DEN     +  + +  +++  +A+              ++ +KFKCGFVLS ++S+L++++   +  NA      G K           R++SLT++F   + +E             +I      G+A+ +S  +  T+  IQS +   +   D I P+  ET++G+W  D RHG+GVCERSDGV YEG WL N+RHGFG T+F DG+ E+G+YQ GKL+FL W+K   P   L+++ +   +  SVK+AR  +++A+ +  + R+ L  +   V+++K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MR T+RG K+FES L AA++V+ G
Sbjct:   36 LPAGRYEFKDSGLYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWAHNRRNGHGVFTREDWVIMGKFDEDFISLGIKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIREGLGVRTSIPYGEVINFFPEEAALAAELLLQAKREAANRAAELTRDGRRGSLLSQRSGDVAELENADDENPGTDEDEPYLTRKLNQTQAAANSTTPAITGGLRDLRMSSKFKCGFVLSSQRSELVLRRQNKLVGNAPPAAGTGRKSREAGARSGRTRARSLTNLFGRSSSRE-------------SIPRMKRQGSANDRS--NLTTYKPIQSESVFTLDQDDAIDPETVETFAGQWESDTRHGYGVCERSDGVTYEGQWLKNQRHGFGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHLLLYNYHIMREVAASVKRARVIAEQARMRAAEARENLENVHAAVERSKQAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRATRRGNKAFESALDAALEVIAG 567          
BLAST of Junctophilin vs. TrEMBL
Match: A0A3R7GDK8 (Junctophilin-2 OS=Clonorchis sinensis OX=79923 GN=JPH2 PE=4 SV=1)

HSP 1 Score: 494.197 bits (1271), Expect = 1.964e-152
Identity = 255/534 (47.75%), Postives = 354/534 (66.29%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHL----------LLKSATDENST---------------------NLS-------FTSNHVDKNGSAS--------KLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798
            LPAGRYEFKD+GIYIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWAN++R+G+GIF +EDW++MGKF + FI++GVK KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+R+GLGVRTSIPYGE+  F PEE  L           L++A   N +                     NL        F+       G AS        ++  KF+CGFVLS ++S+L+ ++   ++   K ++G          R++SLT++F+    +E     +IH+        +   G+AS ++ +      T +S+ T+D    D I P+  ET++G+W  D RHG+GVCERSDGV YEG W  N+RHG+G T+F DG+ E+G+YQ GKL+FL W+K   P   L+++ + + +  SVK+AR  +++A+ +  + R+ L  +   V+ +K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MRVTKRG  +FES L+AA  V+ G
Sbjct:   12 LPAGRYEFKDAGIYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWANNRRNGHGIFTREDWVIMGKFVDDFISVGVKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIRDGLGVRTSIPYGEVINFFPEEAALAAEMKAKRRAALEAANTINESQKLGRHGSLLSQRSGEAAEMENLEAPEEDEPFSGRRATPTGGASNTAGLRELRMSCKFRCGFVLSSQRSELVQRRQDKLSGVSKPRRGRDVVPRSGHHRTRSLTNLFTRSLSRE-----SIHR--------FKRQGSASERTTYGKADETTPESVFTLDQE--DAIDPETVETFAGQWENDSRHGYGVCERSDGVTYEGQWFKNQRHGYGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHMLLYNYHIKMGVGSSVKRARVIAEQARLRATEARENLENVHMIVELSKKAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRVTKRGNLAFESALEAAQGVLAG 530          
BLAST of Junctophilin vs. TrEMBL
Match: A0A4S2MK81 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000339 PE=4 SV=1)

HSP 1 Score: 493.426 bits (1269), Expect = 3.079e-152
Identity = 253/534 (47.38%), Postives = 354/534 (66.29%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLK-SATDENSTNLSFTSNHVDK-----------NGSASKLPN----------------------------------KFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798
            LPAGRYEFKD+GIYIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWAN++R+G+GIF +EDW++MGKF + FI++GVK KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+R+GLGVRTSIPYGE+  F PEE  L  +  A    +   + T N   K           +G A+++ N                                  KF+CGFVLS ++S+L+ ++   ++   K ++G          R++SLT++F+    +E     +IH+        +   G+AS ++ +  +   T +S+ T+D    D I P+  ET++G+W  D RHG+GVCERSDGV YEG W  N+RHG+G T+F DG+ E+G+YQ GKL+FL W+K   P   L+++ + + +  SVK+AR  +++A+ +  + R+ L  +   V+ +K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MRVTKRG  +FES L+AA  V+ G
Sbjct:   12 LPAGRYEFKDAGIYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWANNRRNGHGIFTREDWVIMGKFVDDFISMGVKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIRDGLGVRTSIPYGEVINFFPEEAALAAEMKAKRRAALEAANTVNESQKLGRRGSLLSQRSGEAAEMENLEAPEEDEPFSGRRATPTGGATTTAGLRELRMSCKFRCGFVLSSQRSELVQRRQDKLSGVSKPRRGRDVVPRSGHHRTRSLTNLFTRSLSRE-----SIHR--------FKRQGSASERTTYGKVDETTPESVFTLDQE--DAIDPETVETFAGQWENDSRHGYGVCERSDGVTYEGQWFKNQRHGYGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHMLLYNYHIKMGVGSSVKRARVIAEQARLRATEARENLENVHMIVELSKKAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRVTKRGNLAFESALEAAQGVLAG 530          
BLAST of Junctophilin vs. TrEMBL
Match: G7YME1 (Junctophilin-2 OS=Clonorchis sinensis OX=79923 GN=CLF_112255 PE=4 SV=1)

HSP 1 Score: 494.582 bits (1272), Expect = 1.801e-150
Identity = 255/534 (47.75%), Postives = 354/534 (66.29%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHL----------LLKSATDENST---------------------NLS-------FTSNHVDKNGSAS--------KLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798
            LPAGRYEFKD+GIYIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWAN++R+G+GIF +EDW++MGKF + FI++GVK KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+R+GLGVRTSIPYGE+  F PEE  L           L++A   N +                     NL        F+       G AS        ++  KF+CGFVLS ++S+L+ ++   ++   K ++G          R++SLT++F+    +E     +IH+        +   G+AS ++ +      T +S+ T+D    D I P+  ET++G+W  D RHG+GVCERSDGV YEG W  N+RHG+G T+F DG+ E+G+YQ GKL+FL W+K   P   L+++ + + +  SVK+AR  +++A+ +  + R+ L  +   V+ +K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MRVTKRG  +FES L+AA  V+ G
Sbjct:   12 LPAGRYEFKDAGIYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWANNRRNGHGIFTREDWVIMGKFVDDFISVGVKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIRDGLGVRTSIPYGEVINFFPEEAALAAEMKAKRRAALEAANTINESQKLGRHGSLLSQRSGEAAEMENLEAPEEDEPFSGRRATPTGGASNTAGLRELRMSCKFRCGFVLSSQRSELVQRRQDKLSGVSKPRRGRDVVPRSGHHRTRSLTNLFTRSLSRE-----SIHR--------FKRQGSASERTTYGKADETTPESVFTLDQE--DAIDPETVETFAGQWENDSRHGYGVCERSDGVTYEGQWFKNQRHGYGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHMLLYNYHIKMGVGSSVKRARVIAEQARLRATEARENLENVHMIVELSKKAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRVTKRGNLAFESALEAAQGVLAG 530          
BLAST of Junctophilin vs. TrEMBL
Match: W6UC37 (Junctophilin-1 OS=Echinococcus granulosus OX=6210 GN=EGR_06401 PE=4 SV=1)

HSP 1 Score: 440.654 bits (1132), Expect = 3.122e-133
Identity = 246/535 (45.98%), Postives = 330/535 (61.68%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPE-------------EKHLLLKSATDEN-STNLSFTSNHVDKNGSA--SKLPNKFKCGFVLSGKKSDL--------------LIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTIS--------------VYSVPGNAS---PKSFHSSL--TFNTIQSI-----ATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLW--TKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLT-EIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798
            LPAGRYEF+D+GIYIGEWL+EKAVG+GL+TKDKSQGE+TGLW +GSEK GVFLWP+APGAMYEGEWA ++R+G+G+F +EDW++MGKF++ FIT+GVK K+ + GKFEG FE+G P FG+ETY D GTYCGDYK+G+REGLGVR SI YGE+    PE              K   L S    N    +SF    +D    A  S   N      V+ G++ D                    RH NA  +     +    L+S  S L  K L   K+   N FG  +              +++ P       PKS+   +   +N+  S+     A  D    D IA D  E YSGEW  D RHG+GVCER+DG+ Y G W  N+RHGFG T+F DG+FE+G+Y NGKL++L       P   L++  +   ++K V +A  A ++AQ+K ++ R++++ ++ + ++KAK AA+ AREYSLE R+LV+EMYPD+EQPGI+ L DIVRMMRVT++G  +FE+ LQ+A DVV G
Sbjct:   62 LPAGRYEFRDNGIYIGEWLDEKAVGLGLITKDKSQGEYTGLWEAGSEKSGVFLWPNAPGAMYEGEWAMNRRNGFGVFNREDWVIMGKFEDDFITMGVKGKDNAPGKFEGRFENGFPAFGVETYGDKGTYCGDYKNGIREGLGVRRSITYGEVLELYPEIKKASNSSKLEDLRKRGKLPSPLKINLDRRMSFDQGSIDVPCEAVWSSENNSDGVDGVMDGEECDPEPYTAPRDTTSYLECAMGHRHQNATYRLMVAQRCGFMLSSKRSELFIKRLNKLKHPRINPFGCTTPEAPERKRTQSLSMLFTYPEETMPTLPKSYVRQMKDLYNSSNSLPKIIPAENDTLELDLIADDTVEVYSGEWFSDARHGYGVCERTDGLAYYGQWFKNQRHGFGHTRFPDGTFEQGKYHNGKLVYLALPAGNKPHMVLYNRHVMQEVQKMVHRAMLAGEQAQKKAIEAREQVSMKVLDYIEKAKAAASCAREYSLEARELVREMYPDFEQPGIKYLEDIVRMMRVTRQGSPTFEAALQSAKDVVAG 596          
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph1b (junctophilin-1 [Source:NCBI gene;Acc:103024555])

HSP 1 Score: 206.453 bits (524), Expect = 1.763e-55
Identity = 144/446 (32.29%), Postives = 219/446 (49.10%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W + KA G G+ T  K QGE++G W+SG E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    +  ++EG + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG +   +       L S   E S          D        P   + GFVL+      L    R        +KGL R  SL   F +L +    ++++   +   +    +     S    +S+++F   +  A       D +     E Y GEW  D+R+GFGV ERS+G+ YEG W NNKRHG+G T F DG+ EEG+Y+N  L+    K+  +  L + +    + ++V+ A  A+  A+ K      +    R   + A +A+  A + S   R + +++ P++ QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSSGFEVVGVYTWPS--GNTYQGHWAQGKRHGLGVESKGRWLYRGEWTHGFKGRYGVRQSLNTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQSNGSVLHERLTDS-------PAGTRGGFVLNFHSDSELGGPAR--------KKGLFRRGSL---FGSLKQLRKSDSRSSISSKRSSARSDATMSRISSSDANSTISFGEGEG-ADEYTPMEDNVDATTTEAYMGEWKNDKRNGFGVSERSNGMKYEGEWTNNKRHGYGCTMFPDGTREEGKYKNNVLVRGIKKQ--LIPLKNTKTKQKVDRAVEGAIRAAAIAKTKVEIATSRTAHARAKGEAADQASLSACQNSDVARAVARDLSPNFHQPG 422          
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph1a (junctophilin-1-like [Source:NCBI gene;Acc:103033137])

HSP 1 Score: 201.06 bits (510), Expect = 8.446e-54
Identity = 147/447 (32.89%), Postives = 223/447 (49.89%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNL-SFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W + KA G G+ T  + QGE+ G W+ G E  GV+ WPS  G  Y+G W+  KR G G+  K  W+  G++  GF    GV+    +  +++G + +G    +G+ETYADGGTY G +  G+R G GVR S+PYG           ++++S    +  +L S  SN V    +  + P   + GFVL+               A  K + GL R  SL   F +L  ++L  +++         S  S   ++   S  S       +    M+    D +     ETY GEW  D+R+GFG+ ERS+G+ YEG WLNNKR+G+G T F DG+ EEG+Y+N  L+     R  I  L + +    ++++V+ AR  +  A+ K      + T  R   + A +AA  A   S   R + +E+ P + QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPQGQGEYAGAWSHGFEIVGVYTWPS--GNTYQGYWSQGKRHGLGVETKGRWMYRGEWSHGFKGRYGVRQGSNTPARYDGTWSNGLQDGYGVETYADGGTYQGQWMGGMRHGYGVRQSVPYGMA---------MVIRSPLRTSLASLRSVQSNGVVMPDTTGEQPVSTRGGFVLN-------FHSEAEAQAGGKKKPGLFRRGSL---FGSL--RQLRKSESKSSISSKRSSAMSRISSSDGNSSISYGEGEAQEEFLPME----DNVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWLNNKRNGYGCTIFPDGTREEGKYKNNVLVR--GIRKQIIPLKNPKTKEKVERAVEGARRGAAIARMKVEIATSRTTHARAKSEAADQAAVAAGHESDLARAVARELSPSFHQPG 418          
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:103038422])

HSP 1 Score: 201.445 bits (511), Expect = 1.669e-53
Identity = 145/451 (32.15%), Postives = 215/451 (47.67%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNH------VDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDT-IAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
             GR+ F D G Y G W   KA G G+ T  K QGE+ G W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    + GK+EG + +G    +G ETY+DGGTY G +  G+R G G+R S+PYG + A +       + S   E+S   +  +            GS    P   + GFVL+      L+K         K  KGL R     S+ S L  ++  +  ++        S  S  G ++  S  S +           ++ AG+  +     E+Y+GEW  D+R G GV  RSDG+ Y+G W+ NKRHG+G T F DG+ EEG+Y+   L+    KR  +  L + ++   + ++V+ A  A+  A++K      +    R   + A  AA  A+E     R   KE  P ++  G
Sbjct:    4 GGRFNFDDGGSYCGGWEEGKAHGHGICTGPKGQGEYAGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLENKGKWVYKGEWTHGFKGRYGVRESTGASGKYEGTWNNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGIRQSVPYG-MAAVIRSPLRTSINSLRSEHSNGTALLAGERAGVGPGVGPGSLVASPAVSRGGFVLTAHSEAELLKG--------KKNKGLFR----RSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGESELPAGEEDVDATATESYAGEWKNDKRTGCGVSRRSDGLCYQGEWMGNKRHGYGCTTFPDGTKEEGKYKQNVLVS--GKRKHLIPLRASKIREKVDRAVEGAEKAADIAKQKSEIALSRTAHARGKAEAAIAAAQKAQEECRLARVAAKEFSPSFQHRG 437          
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:103038422])

HSP 1 Score: 201.83 bits (512), Expect = 3.100e-53
Identity = 145/451 (32.15%), Postives = 215/451 (47.67%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNH------VDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDT-IAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
             GR+ F D G Y G W   KA G G+ T  K QGE+ G W+ G E  GV+ WPS  G  Y+G WA  KR G G+  K  W+  G++  GF    GV+    + GK+EG + +G    +G ETY+DGGTY G +  G+R G G+R S+PYG + A +       + S   E+S   +  +            GS    P   + GFVL+      L+K         K  KGL R     S+ S L  ++  +  ++        S  S  G ++  S  S +           ++ AG+  +     E+Y+GEW  D+R G GV  RSDG+ Y+G W+ NKRHG+G T F DG+ EEG+Y+   L+    KR  +  L + ++   + ++V+ A  A+  A++K      +    R   + A  AA  A+E     R   KE  P ++  G
Sbjct:    4 GGRFNFDDGGSYCGGWEEGKAHGHGICTGPKGQGEYAGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLENKGKWVYKGEWTHGFKGRYGVRESTGASGKYEGTWNNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGIRQSVPYG-MAAVIRSPLRTSINSLRSEHSNGTALLAGERAGVGPGVGPGSLVASPAVSRGGFVLTAHSEAELLKG--------KKNKGLFR----RSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGESELPAGEEDVDATATESYAGEWKNDKRTGCGVSRRSDGLCYQGEWMGNKRHGYGCTTFPDGTKEEGKYKQNVLVS--GKRKHLIPLRASKIREKVDRAVEGAEKAADIAKQKSEIALSRTAHARGKAEAAIAAAQKAQEECRLARVAAKEFSPSFQHRG 437          
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph2 (junctophilin-2 [Source:NCBI gene;Acc:103043867])

HSP 1 Score: 199.134 bits (505), Expect = 3.718e-52
Identity = 150/465 (32.26%), Postives = 226/465 (48.60%), Query Frame = 2
Query:  374 GRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVD----KNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDV----FETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVR 1723
            GR+EF D G Y G W   KA G G+ T  K QGEF+G WN G E  GV+ WPS  G  YEG W+  KR G G+  K  W+  G++  GF    G +    S  K+EG + +G    +G ETYADGGT+ G +  G+R G GVR S+PYG + A +       L S   E+S N +     V      N S  + P+    G    G    L +      +  K  +KGL R  SL      LTK E   ++    +    +S        S  +  ++ T +  +S    +      +  D+     E Y GEW  D+R G+G+ ERS G+ YEG WL+N+RHG+G T F++G  EEG+Y +  L+    K+  +  L   ++   +++SV+ A+ A+  A++K      + +  +   + A +A+  A   S   R + +E+ P + QPG      R+L +I +
Sbjct:    4 GRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEFSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVETKGHWVYKGEWTHGFKGRYGSRVSLASGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYG-MAAVVRSPLRNSLTSLRSEHS-NGTLLQQDVPLITTTNASGQESPSPTPIGPSRGGFALTLHVDP----DQVKPKKKGLFRRGSL---LGKLTKSE---SRTSLSSQKSKLSFLRSDSALSSAASDANSTISLGESEGEAEGGEFPPVEADIDATTTEVYLGEWKNDKRSGYGISERSSGLKYEGEWLDNQRHGYGCTTFAEGGKEEGKYMHNMLVKAVKKK--LIQLKGTKIKQKVERSVEGAQRAAAIAKQKAEIANSRTSHAKSKGEAADQASHGANNESSIARVVARELSPSFYQPGPEYLKKRVLQEISK 452          
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009496.1 (pep scaffold:Pmarinus_7.0:GL480437:14153:18284:1 gene:ENSPMAG00000008588.1 transcript:ENSPMAT00000009496.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 97.8265 bits (242), Expect = 1.354e-22
Identity = 82/291 (28.18%), Postives = 129/291 (44.33%), Query Frame = 2
Query:  743 GTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVD------KNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIAT----MDMSAG----------DTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEK 1555
            GTY G +  G+R G GVR S+PYG + + +       L S   E  TN S             ++G  +      + GFVL+G            ++     Q+G K                L + K    +   ++S       +   SF S    + I S A+    + +S G          D +  +  ETY+GEW  D+R GFGV +RSDG+ YEG WL N+R+G+G T + DG  EEG+Y+ G L     KR  +  L + +    ++++V+ A+  +  A++K
Sbjct:    1 GTYQGQWAGGMRHGYGVRNSVPYG-LASVVRSPLRTSLSSLRSEQ-TNGSIVGPVGGGAGGSLRSGDDAGSAVGSRGGFVLTG------------VHHSDSEQQGGKAGGKRGGGGLFRRGSLLGSLKFRRSDSKASLSSE----RSKRSSFRSEAGMSAISSAASDGTSLAVSLGEPETELFDSEDLVEANTTETYTGEWKGDKRSGFGVSQRSDGLRYEGEWLANRRNGYGRTSYPDGRSEEGKYRQGTLTR--GKRRSLVPLRASKTRAKVERAVEAAQRGATVAKQK 271          
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: RSPH10B2 (radial spoke head 10 homolog B2 [Source:HGNC Symbol;Acc:HGNC:34385])

HSP 1 Score: 53.9138 bits (128), Expect = 1.494e-7
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 2
Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFE-EGQYQNGK 1435
            Y GEW  + RHG+G+     G IYEG WLNN+RHG G  ++     E  GQ+++GK
Sbjct:   64 YCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGK 119          

HSP 2 Score: 48.9062 bits (115), Expect = 5.296e-6
Identity = 23/58 (39.66%), Postives = 33/58 (56.90%), Query Frame = 2
Query: 1262 FETYSGEWVQDQRHGFGVC--ERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQN 1429
            F +YSG W   +RHG G+   +      Y G W +N RHG+GI ++  G+  EGQ+ N
Sbjct:   36 FVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYPSGNIYEGQWLN 93          
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: RSPH10B2 (radial spoke head 10 homolog B2 [Source:HGNC Symbol;Acc:HGNC:34385])

HSP 1 Score: 52.7582 bits (125), Expect = 3.393e-7
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 2
Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFE-EGQYQNGK 1435
            Y GEW  + RHG+G+     G IYEG WLNN+RHG G  ++     E  GQ+++GK
Sbjct:  103 YCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGK 158          
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003398.1 (pep scaffold:Pmarinus_7.0:GL476560:333524:339285:-1 gene:ENSPMAG00000003108.1 transcript:ENSPMAT00000003398.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.7506 bits (112), Expect = 1.496e-6
Identity = 28/83 (33.73%), Postives = 45/83 (54.22%), Query Frame = 2
Query: 1265 ETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKL--IFLWTKRNPIFFLHSFRMGLHIK 1507
            E Y GEW + +RHG G    +DG  Y G + N    G G+  F DGS  EG++  GK   + ++++ + + F   F+ G H++
Sbjct:   14 EEYQGEWKEGRRHGLGQLRFTDGTHYLGQFENGLFSGCGVLAFPDGSRFEGEFSQGKFHGVGVFSRSDGMMFEGEFKNG-HVE 95          

HSP 2 Score: 45.4394 bits (106), Expect = 8.372e-6
Identity = 25/60 (41.67%), Postives = 36/60 (60.00%), Query Frame = 2
Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSF----EEGQYQNGKL 1438
            + GE+ Q + HG GV  RSDG+++EG + N    G+G+  F DGS      EG ++N KL
Sbjct:   62 FEGEFSQGKFHGVGVFSRSDGMMFEGEFKNGHVEGYGLLTFPDGSHGLPRNEGIFENNKL 121          
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO41562 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3X5])

HSP 1 Score: 137.502 bits (345), Expect = 8.091e-35
Identity = 113/401 (28.18%), Postives = 178/401 (44.39%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFA---FLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPI-FFLHSFRMGLHIKKSVKQARNASKKAQEK 1555
            +  GR++F+D G Y GEW N KA G G+ T  K Q  + G W++G E  GV++WP+  G  YEGEW   KR G G+  +  WI  G++++GF                         +G++    G  Y G + SGL+EG G+       E++A   +   +    ++S     S          +   S S+  N    G + + +K     ++   +   + H              S  +  E  N  N       T SV S  G+ S +    SL  ++  ++   +  A + + P V E Y G+W  D+RHG+G+ E SDG  Y G W  N RHG G+  + D S  EG+++N  L+    K+ PI   +  FR  L +  + + A+ AS  A +K
Sbjct:    1 MSGGRFDFEDGGTYCGEWRNGKAHGYGICTGPKGQARYEGSWHNGFELSGVYVWPN--GHRYEGEWYCGKRHGLGVEYRGKWIYQGEWEDGFKAR----------------------YGVQRSQSGARYEGSWTSGLQEGYGI-------EVYANGGYYYGQWKTGMRSGYGIRSAKRDPKVTITNYARSISRQSNAESNGVIPTKQK-----RQGGELPPAEPH--------------SPKSGSESDNASN-------TGSVNSTVGSGSTQLADGSL--DSTVAVTQTEPEA-EPVKP-VRELYKGDWKNDKRHGYGILEASDGYKYIGQWHENMRHGLGVACYPDSSKYEGEFENDNLVVDIKKKGPIKTLVTRFRQRLQV--ACEAAQQASDLAVQK 338          
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO41170 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S530])

HSP 1 Score: 51.2174 bits (121), Expect = 7.540e-7
Identity = 22/56 (39.29%), Postives = 38/56 (67.86%), Query Frame = 2
Query: 1265 ETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNG 1432
            E Y GEW  D+R G+G    SDG +YEG W ++K++G G+ + ++ +  EG++++G
Sbjct:  110 EYYEGEWYADKRSGWGRMYYSDGAVYEGEWYDDKQNGEGMLRLANENRYEGEWKDG 165          

HSP 2 Score: 49.2914 bits (116), Expect = 2.983e-6
Identity = 24/55 (43.64%), Postives = 33/55 (60.00%), Query Frame = 2
Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGK 1435
            YSG W  D+RHG+G    S    YEG W  +KR G+G   +SDG+  EG++ + K
Sbjct:   89 YSGGWKNDKRHGYGTNFYSPTEYYEGEWYADKRSGWGRMYYSDGAVYEGEWYDDK 143          
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO33639 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRL1])

HSP 1 Score: 49.6766 bits (117), Expect = 1.262e-6
Identity = 25/57 (43.86%), Postives = 36/57 (63.16%), Query Frame = 2
Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSD-GSFEEGQYQNGKL 1438
            Y G WV DQRHG+G    ++  I+EG W+ NKRHG G   +++ GS  EG +  G++
Sbjct:   89 YEGYWVNDQRHGYGTYTYANKDIFEGEWVQNKRHGQGTYTYAETGSRFEGTWFQGRM 145          
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO30644 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T074])

HSP 1 Score: 49.6766 bits (117), Expect = 6.440e-6
Identity = 25/66 (37.88%), Postives = 36/66 (54.55%), Query Frame = 2
Query: 1238 GDTIAPDVFETYSGEWVQDQRHGFGVC--ERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQN 1429
            GD    ++   YSGEW   +RHG GV   +R     Y+G WLNN RHG+    +  G+  EG +++
Sbjct:  148 GDYSCSNLPAVYSGEWRHGKRHGRGVLKYDREGHSYYDGHWLNNMRHGYARRVYKGGNVYEGDWKD 213          
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO29067 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4P6])

HSP 1 Score: 45.0542 bits (105), Expect = 7.541e-6
Identity = 23/55 (41.82%), Postives = 32/55 (58.18%), Query Frame = 2
Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGK 1435
            Y G + + +RHG GV    DG IY+G W    R G G  K+++G   EG ++NGK
Sbjct:   15 YEGHYSKGKRHGQGVMYYPDGSIYDGTWSEGLRSGKGKYKYANGDVYEGNWKNGK 69          
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph1a (junctophilin 1 [Source:NCBI gene;Acc:101173340])

HSP 1 Score: 214.157 bits (544), Expect = 5.036e-58
Identity = 151/452 (33.41%), Postives = 224/452 (49.56%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFL-PEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQ----SIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +  GR++F D G Y G W + KA G G+ T  K QGE+ G W+ G E  GV+ WPS  G  Y+G W+  KR G G+  K  WI  G++  GF    GV+    +  ++EG + +G    +G+ETY DGGTY G +  G+R G GVR S+PYG       P    +    +   N T L   S+  D        P   + GFVL+    S+++  K          +KGL R  SL      L K +   + +  ++        S   +A+     SS   +TI      +A  D+   D +     ETY GEW  D+R+GFGV ERS+G+ YEG WLNNKRHG+G T F D + EEG+Y+N  L+    K+  +  L + +    + ++V+ A+ A+  A+ K      +    R   + A++AA  A   S   R + +E+ P++ QPG
Sbjct:    1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYAGSWSHGFEIVGVYTWPS--GNTYKGYWSQGKRHGLGVENKGKWIYRGEWSHGFKGRYGVRQSHNTPARYEGTWSNGLQDGYGIETYGDGGTYQGQWMGGMRHGYGVRQSVPYGMATVIRSPLRTSMASLRSEQSNGTVLQDLSSPAD-------TPTGSRGGFVLNFHSDSEVVTGK----------KKGLFRRGSLFGSLRQLRKSDSRTSISSKRS--------SARSDATMSRISSSDANSTISIGDGELADDDLHLEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWLNNKRHGYGCTVFPDATKEEGKYKNNVLVRGIRKQ--LIPLKNPKTKEKVDRAVEGAQRAAAIARSKVEIAASRTAHARTKSEAAEQAAISAVHDSEIARAVARELSPNFYQPG 423          
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:101163737])

HSP 1 Score: 213.386 bits (542), Expect = 2.290e-57
Identity = 152/448 (33.93%), Postives = 221/448 (49.33%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFL-PEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
             GR+ F D G Y G W   KA G G+ T  K QGE+ G W  G E  GV+ WPS  G  Y+G WA  KR G GI  K  W+  G++  GF    G++    + GK+EG + +G    +G ETY+DGGT+ G +  G+R G GVR S+PYG       P    +    +  E+S   +  S  +   GS+   P   + GFVL+      L+K         K + GL R     SI S L  ++  +  ++        S  S  G ++  S  S +  N+  S+   D     A D +     ETY GEW  D+R GFGV  RSDG+ YEG WL+NKRHG+G T F DG+ EEG+Y+  + I +  KR  +  L + ++   + ++V+ A+ A+  A++K      +    +   + A  AA  A+E S   R   K+  P ++ PG
Sbjct:    4 GGRFNFDDGGSYCGGWEEGKAHGYGICTGPKGQGEYCGSWAHGFELLGVYTWPS--GNTYQGTWAQGKRHGVGIENKGRWVYKGEWTHGFKGRYGLRESTGTSGKYEGTWNNGLQDGYGTETYSDGGTFQGQWVGGMRHGYGVRQSVPYGMAAVIRSPLRTSINSLRSGSEHSNGTALVS--MCSTGSSGSSPAVSRGGFVLTAHSEAELLKG--------KRKSGLFR----RSILSGLKLRKSESRSSLASQRSKQSSFRSEAGMSTVSSAASDV--NSTISLGDADAELAVADDDVDATTTETYCGEWKNDKRTGFGVSRRSDGLQYEGEWLSNKRHGYGCTTFPDGTKEEGKYK--QNILVSGKRKNLIPLRASKIREKVDRAVEGAQKAADIARQKAEIALSRTAHAQGKAEAAVAAAQKAQEESRMARVTAKQFSPSFQHPG 431          
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:101163737])

HSP 1 Score: 208.764 bits (530), Expect = 1.340e-55
Identity = 156/467 (33.40%), Postives = 224/467 (47.97%), Query Frame = 2
Query:  371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGE---IFAFLPEEKHLLLKSATDENSTNLS-----------------FTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
             GR+ F D G Y G W   KA G G+ T  K QGE+ G W  G E  GV+ WPS  G  Y+G WA  KR G GI  K  W+  G++  GF    G++    + GK+EG + +G    +G ETY+DGGT+ G +  G+R G GVR S+PYG    I + L    + L   +   N T L                   TS  +   GS+   P   + GFVL+      L+K         K + GL R     SI S L  ++  +  ++        S  S  G ++  S  S +  N+  S+   D     A D +     ETY GEW  D+R GFGV  RSDG+ YEG WL+NKRHG+G T F DG+ EEG+Y+  + I +  KR  +  L + ++   + ++V+ A+ A+  A++K      +    +   + A  AA  A+E S   R   K+  P ++ PG
Sbjct:    4 GGRFNFDDGGSYCGGWEEGKAHGYGICTGPKGQGEYCGSWAHGFELLGVYTWPS--GNTYQGTWAQGKRHGVGIENKGRWVYKGEWTHGFKGRYGLRESTGTSGKYEGTWNNGLQDGYGTETYSDGGTFQGQWVGGMRHGYGVRQSVPYGMAAVIRSPLRTSINSLRSGSEHSNGTALLDRTGAIVPGPPTVPGTLTTSVSMCSTGSSGSSPAVSRGGFVLTAHSEAELLKG--------KRKSGLFR----RSILSGLKLRKSESRSSLASQRSKQSSFRSEAGMSTVSSAASDV--NSTISLGDADAELAVADDDVDATTTETYCGEWKNDKRTGFGVSRRSDGLQYEGEWLSNKRHGYGCTTFPDGTKEEGKYK--QNILVSGKRKNLIPLRASKIREKVDRAVEGAQKAADIARQKAEIALSRTAHAQGKAEAAVAAAQKAQEESRMARVTAKQFSPSFQHPG 452          
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph2 (junctophilin 2 [Source:NCBI gene;Acc:101175160])

HSP 1 Score: 206.068 bits (523), Expect = 6.886e-55
Identity = 145/459 (31.59%), Postives = 215/459 (46.84%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSN-----HVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIV 1720
            +  GR+EF D G Y G W   KA G G+ T  K QGE++G WN G E  GV+ WPS  G  YEG W+  KR G G+  K  WI  G++  GF    G +    S  K+EG + +G    +G ETYADGGT+ G +  G+R G GVR S+PYG + A +       L S   E+S       +       + +G  + +      G    G    L +       A K  +KGL R  SL             +++    +     S  S   + +  +     +   ++    ++      I     E Y GEW  D+R G+G+ ERS G+ YEG WLNN+RHG+G T F++G  EEG+Y N  L+    KR  +  L   ++   ++++V+ A+ A+  A++K      + T  +     A++AA  A   S   R + KE+ P + QPG   L   V
Sbjct:    1 MSGGRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEYSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVESKGHWIYKGEWTHGFKGRYGTRVSVGSGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYG-MAAVVRSPLRTSLTSLRSEHSNGTVLQQDIPVITTTNTSGEETPVATPTHLGPSRGGFALTLQVDP----EAVKPKKKGLFRRSSLLGKLKKSDSSVSLSSQKSKTSFLRPDSALSSNASDTNSTISGDESLLGVEDFPPVE----SDIDATTTEVYMGEWKNDKRSGYGISERSSGLKYEGEWLNNQRHGYGCTTFAEGGKEEGKYMNNMLVKAMKKR--MIQLKGNKIKQKVERAVEGAQRAAAIAKQKAEIAASRTTHAKAKSDGAEQAAHAANGESSIARLVAKELSPSFYQPGPEYLKKKV 446          
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph2 (junctophilin 2 [Source:NCBI gene;Acc:101175160])

HSP 1 Score: 204.912 bits (520), Expect = 1.535e-54
Identity = 146/455 (32.09%), Postives = 214/455 (47.03%), Query Frame = 2
Query:  365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDL-LIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIV 1720
            +  GR+EF D G Y G W   KA G G+ T  K QGE++G WN G E  GV+ WPS  G  YEG W+  KR G G+  K  WI  G++  GF    G +    S  K+EG + +G    +G ETYADGGT+ G +  G+R G GVR S+PYG               +A   +    S TS           L ++   G VL   + D+ +I       A K  +KGL R  SL             +++    +     S  S   + +  +     +   ++    ++      I     E Y GEW  D+R G+G+ ERS G+ YEG WLNN+RHG+G T F++G  EEG+Y N  L+    KR  +  L   ++   ++++V+ A+ A+  A++K      + T  +     A++AA  A   S   R + KE+ P + QPG   L   V
Sbjct:    1 MSGGRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEYSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVESKGHWIYKGEWTHGFKGRYGTRVSVGSGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYG--------------MAAVVRSPLRTSLTS-----------LRSEHSNGTVL---QQDIPVITTTNTSEAVKPKKKGLFRRSSLLGKLKKSDSSVSLSSQKSKTSFLRPDSALSSNASDTNSTISGDESLLGVEDFPPVE----SDIDATTTEVYMGEWKNDKRSGYGISERSSGLKYEGEWLNNQRHGYGCTTFAEGGKEEGKYMNNMLVKAMKKR--MIQLKGNKIKQKVERAVEGAQRAAAIAKQKAEIAASRTTHAKAKSDGAEQAAHAANGESSIARLVAKELSPSFYQPGPEYLKKKV 419          
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000065993.1 (SMESG000065993.1)

HSP 1 Score: 1768.82 bits (4580), Expect = 0.000e+0
Identity = 897/899 (99.78%), Postives = 898/899 (99.89%), Query Frame = 2
Query:  332 MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNFLLVDADGEHRASRHGSFRRSKKLSTQNISKEIHQKQANKPTIEINHSSMPIKRIESQNCPEDPKLPHKLNQLESIQPITFHPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDAVPFXXXXXXXXXXXXXXXVYVPVGNIMATSRIPSETLSSIISSNTHIDYFNHYSQSNADQSEKILKSKIYXXXXXXXXXXXXXPRRFTVPEIMTQEPVHPTPVTSILRDLQEEVEDENSEFSDTMILMDGGIRKRVSPVPVNHIKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVSATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIKDYKIS 3028
            MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVKKAKEAAALAREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNFLLVDADGEHRASRHGSFRRSKKLSTQNISKEIHQKQANKPTIEINHSSMPIKRIESQNCPEDPKLPHKLNQLESIQPITFHPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDA PFECETPIKEIEEIEEEVYVPVGNIMATSRIPSETLSSIISSNTHIDYFNHYSQSNADQSEKILKSKIYSMNSSSPNSNINNPRRFTVPEIMTQEPVHPTPVTSILRDLQEEVEDENSEFSDTMILMDGGIRKRVSPVPVN+IKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVSATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIKDYKIS
Sbjct:    1 MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVKKAKEAAALAREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNFLLVDADGEHRASRHGSFRRSKKLSTQNISKEIHQKQANKPTIEINHSSMPIKRIESQNCPEDPKLPHKLNQLESIQPITFHPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDAAPFECETPIKEIEEIEEEVYVPVGNIMATSRIPSETLSSIISSNTHIDYFNHYSQSNADQSEKILKSKIYSMNSSSPNSNINNPRRFTVPEIMTQEPVHPTPVTSILRDLQEEVEDENSEFSDTMILMDGGIRKRVSPVPVNNIKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVSATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIKDYKIS 899          
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000001306.1 (SMESG000001306.1)

HSP 1 Score: 285.804 bits (730), Expect = 1.967e-81
Identity = 260/965 (26.94%), Postives = 438/965 (45.39%), Query Frame = 2
Query:  359 SQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFE----DGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNG--SASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIAT-------MDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDC--RKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNF------LLVDADGE----HRASRHGSFRRSKKLSTQ---NISKEIHQKQ--ANKPTIEINHSS-----MPIKRIESQNCP--EDPKLPHKLNQLESIQPITF---HPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDAVPFXXXXXXXXXXXXXXXVYVPVGNIMATSRIPSETLSS----------IISSNTHIDYFNHYSQSNADQSEKILKSKIYXXXXX------XXXXXXXXPRRFTVPEIMTQEPVHPTPVTSI-----LRDLQEEVEDENSEFSDTMILMDGGIRKR-------------VSPVPVNHIKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVS-----ATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIK 3013
            S +  GR++F D G Y+GEW + +A G+G+ T  ++QGEF+G W  G E  GV++WPS  G +Y G W   KR G G+ +K  WI  G+F  GF    GVK    S  KFEG +     DG   FG+ET ADG TY G +  G+R+GLGVR S  Y +            +++AT +NS     ++N  D+      ++ P   + GFVL    ++        INA K+ +   +++     +F  L K++  +T ++     G              S  S+L+ N+  S AT       + + + ++I P+V ETYSG+W +D+R G+GV ER+DG  YEG W NNK+ G+G+T F +G+ EEG+Y+   L+    KR+ IF L   R+   ++++VK A  A+  A+E+ M+   ++  T   +TV+                            + G RI TD +++  +  + + + E  L  ++          ++     L  NY           LL  +D E       SR GSFR S + S +   N     +QKQ  ++KP    N +S      P+    + +C   E PK+ H ++++    P T     P+ Q +   T+  Q+ P  ++H + ++        + +  A+                   V  G+++       E++SS          +   +T  D+F++YS + ++ ++       Y              +     RR +VP IMT +PV     +S+       D+    E  NS  + ++ +++ GIRKR             +SP     I  R ++ + +    D L PLP  +   S  N  + L EGSLPDVS      TK    + R+E  +L ++ +  I  ++++ ++G  VIR   + DW + +   ++++ +N  +   F+ I+K
Sbjct:    2 SVIEGGRFDFDDGGSYVGEWCDGRAHGLGIATGPENQGEFSGEWVMGFESRGVYIWPS--GNIYAGGWMKGKRHGEGVQMKGKWIYKGEFTTGFCGRYGVKESLSSASKFEGSWHLNLFDG---FGVETNADGSTYSGAWSKGVRQGLGVRKSAAYSKAATHKDPSS---VRAATSQNSL---LSANDSDRQAFVDDARRPIDHRSGFVLVTTNNNA------DINANKEKKPSFRKA-----LFRKLRKQK--STGDLRSARMGG-------------SLRSTLSSNSAASQATNHSLPDSLPIPSRESIDPNVIETYSGQWKEDKRAGYGVAERTDGAKYEGEWYNNKKDGYGVTHFPNGTKEEGRYKENVLVQTLHKRHKIFALRHSRLKDSVEEAVKNAVEAAADAKERAMETANQRAQTAKNKTVQSCT-------------------------RSGKRICTDFIQLGVLWLKTRNNIEGKLTGSVVFNNNFS---LLDNQKYLNQNYKPQQMDQLQPNLLNPSDPECLEVSGGSRRGSFRSSFRRSGEKRPNSPDPQNQKQTSSSKPLSGHNPNSNMTPQKPVASPTNVDCYSFEVPKIGHSVSEVAQQTPTTLLTSEPLIQRATA-TLTRQKAP-QKIHSNIINIQPQNPKKEGLHYAI-------------------VQSGDVIKPQIAQIESISSYSEIEPRNVLVKEFDTGNDFFDYYSNNQSELNDGNFIDYEYEERRKIENEVLESKATRLEERRRSVPSIMTSKPVTANLTSSVKYPDNKYDIVHSSEILNS--TTSVYIIENGIRKRMKADENILPRQPPLSPKSNRLIGKRIQNPLNIEPEADELTPLPRNYKIESSHNPHRKL-EGSLPDVSYCNEIKTKTGTLMSRQEASQLSQQRRQEILHEQERQRRGEIVIRMADIKDWFKQNFTIVLILLLNCVIAVGFLHILK 877          
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000004402.1 (SMESG000004402.1)

HSP 1 Score: 199.519 bits (506), Expect = 7.425e-52
Identity = 148/495 (29.90%), Postives = 236/495 (47.68%), Query Frame = 2
Query:  356 YSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEG-----EFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKS---------DLLIKKL-RHINACKKHQKGLKRSKSLTS----------------IFSALTKKELYNTKNIHKNHFGTI-----SVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAP----------DVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMD-CRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696
            +S    G+++FKD G YIGEW + +A G G+ T   +QGE++G W+ G E CGV++WPS  G +YEG W   KR G G+ +   W+  G F  GF    GVK+   +  ++EG     EF DG   +G+ET ADG TY G +    R+GLGV  S  +G    F          S    +  +   +SN + K+  A+++ N F   F  +  KS         ++L K   +H ++ K  Q      +S  S                I    + + L   + +  N    +     S+ S           S+L  ++  S+     ++  ++ P          +  ETY+G+W ++ R G GV ERSDG+ Y G WLNNKRHG+GIT F D + EEG+Y++  LI    +++ IF +   R+   +   V++A + ++ A+ K ++   ++          A+  A  AR  S   R + K++ P++EQPG
Sbjct:    7 FSSKSGGKFDFKDGGTYIGEWCDGRAHGFGIATGPNNQGEYSGDWSVGFENCGVYIWPS--GNVYEGLWMKGKRHGEGVQVMGRWVYKGSFTTGFFGRYGVKSSLYTQSRYEGCWHLNEF-DG---YGIETCADGSTYAGMWFKNQRKGLGVSHSAQFGLANDFRDSRDSRPSMSDMSMHFGDCRESSNSIYKDCLANEIRNGFVLCFHSNKYKSKHHELSEIGNVLKKSFHKHQSSHKSDQTSTPTDQSSKSFKLHKKLLLHLRRKKPILDQRSARSLSRQRTVENNENEFLRNPSGSLKSTNSRDHSNQVASTLPTSSGSSLGKAGSNSFSSVVPGYDILSSIPKETVETYAGQWNENTRTGLGVAERSDGLKYIGEWLNNKRHGYGITCFPDNTIEEGRYKDNVLIQQLNRKSRIFLVKHSRLKNLVDDFVQKALDVAQDAKIKAVETAYQRAQTALAAAISAQARADDARTLSKSARNIAKQIAPNFEQPG 495          
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000053274.1 (SMESG000053274.1)

HSP 1 Score: 48.1358 bits (113), Expect = 4.260e-6
Identity = 25/57 (43.86%), Postives = 31/57 (54.39%), Query Frame = 2
Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441
            Y G++V D   G G  +   G  YEG +LNN  HG G   F DGSF EG +   +LI
Sbjct:   45 YDGDFVNDLMQGNGTLKFPSGAKYEGDFLNNMFHGEGKYTFPDGSFYEGNFDKNRLI 101          
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000011788.1 (SMESG000011788.1)

HSP 1 Score: 49.2914 bits (116), Expect = 6.120e-6
Identity = 23/56 (41.07%), Postives = 37/56 (66.07%), Query Frame = 2
Query: 1265 ETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNG 1432
            E Y GEW + +R+G+G    +DG +YEG W N++  G G+ +  +G+  EGQ++NG
Sbjct:  116 EFYEGEWYEGKRNGWGRMYEADGNVYEGEWENDQMCGQGMLRNKNGNRYEGQWKNG 171          
The following BLAST results are available for this feature:
BLAST of Junctophilin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
JPH36.244e-5433.03junctophilin 3 [Source:HGNC Symbol;Acc:HGNC:14203][more]
JPH23.815e-5233.05junctophilin 2 [Source:HGNC Symbol;Acc:HGNC:14202][more]
JPH11.402e-5032.15junctophilin 1 [Source:HGNC Symbol;Acc:HGNC:14201][more]
JPH41.593e-4628.82junctophilin 4 [Source:HGNC Symbol;Acc:HGNC:20156][more]
JPH41.593e-4628.82junctophilin 4 [Source:HGNC Symbol;Acc:HGNC:20156][more]
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BLAST of Junctophilin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
jph-13.660e-5730.38JunctoPHilin [Source:UniProtKB/TrEMBL;Acc:Q22667][more]
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BLAST of Junctophilin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
jp3.165e-5435.66gene:FBgn0032129 transcript:FBtr0079861[more]
jp3.165e-5435.66gene:FBgn0032129 transcript:FBtr0079860[more]
jp3.165e-5435.66gene:FBgn0032129 transcript:FBtr0304056[more]
jp3.165e-5435.66gene:FBgn0032129 transcript:FBtr0304057[more]
CG304291.142e-638.10gene:FBgn0050429 transcript:FBtr0072450[more]
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BLAST of Junctophilin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
jph1b1.810e-5632.74junctophilin 1b [Source:ZFIN;Acc:ZDB-GENE-060616-3... [more]
jph1b1.810e-5632.74junctophilin 1b [Source:ZFIN;Acc:ZDB-GENE-060616-3... [more]
jph1a3.968e-5431.56junctophilin 1a [Source:ZFIN;Acc:ZDB-GENE-040724-2... [more]
jph31.688e-5331.65junctophilin 3 [Source:ZFIN;Acc:ZDB-GENE-060503-41... [more]
jph22.473e-5331.88junctophilin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-98... [more]
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BLAST of Junctophilin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
JPH32.339e-5533.26junctophilin 3 [Source:NCBI gene;Acc:105947054][more]
ing29.145e-5532.00inhibitor of growth family member 2 [Source:Xenbas... [more]
ing21.595e-5432.00inhibitor of growth family member 2 [Source:Xenbas... [more]
ing21.647e-5432.00inhibitor of growth family member 2 [Source:Xenbas... [more]
ing22.516e-5432.00inhibitor of growth family member 2 [Source:Xenbas... [more]
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BLAST of Junctophilin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Jph32.284e-5435.08junctophilin 3 [Source:MGI Symbol;Acc:MGI:1891497][more]
Jph32.284e-5435.08junctophilin 3 [Source:MGI Symbol;Acc:MGI:1891497][more]
Jph23.422e-5232.34junctophilin 2 [Source:MGI Symbol;Acc:MGI:1891496][more]
Jph23.422e-5232.34junctophilin 2 [Source:MGI Symbol;Acc:MGI:1891496][more]
Jph16.037e-5232.07junctophilin 1 [Source:MGI Symbol;Acc:MGI:1891495][more]
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BLAST of Junctophilin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9ET77|JPH3_MOUSE1.597e-5335.08Junctophilin-3 OS=Mus musculus OX=10090 GN=Jph3 PE... [more]
sp|Q9GKY7|JPH2_RABIT2.055e-5332.99Junctophilin-2 OS=Oryctolagus cuniculus OX=9986 GN... [more]
sp|Q8WXH2|JPH3_HUMAN2.999e-5333.03Junctophilin-3 OS=Homo sapiens OX=9606 GN=JPH3 PE=... [more]
sp|Q2PS20|JPH2_RAT6.777e-5332.73Junctophilin-2 OS=Rattus norvegicus OX=10116 GN=Jp... [more]
sp|Q9BR39|JPH2_HUMAN1.832e-5133.05Junctophilin-2 OS=Homo sapiens OX=9606 GN=JPH2 PE=... [more]
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BLAST of Junctophilin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183ALC74.191e-15546.44Uncharacterized protein OS=Echinostoma caproni OX=... [more]
A0A3R7GDK81.964e-15247.75Junctophilin-2 OS=Clonorchis sinensis OX=79923 GN=... [more]
A0A4S2MK813.079e-15247.38Uncharacterized protein OS=Opisthorchis felineus O... [more]
G7YME11.801e-15047.75Junctophilin-2 OS=Clonorchis sinensis OX=79923 GN=... [more]
W6UC373.122e-13345.98Junctophilin-1 OS=Echinococcus granulosus OX=6210 ... [more]
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BLAST of Junctophilin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
jph1b1.763e-5532.29junctophilin-1 [Source:NCBI gene;Acc:103024555][more]
jph1a8.446e-5432.89junctophilin-1-like [Source:NCBI gene;Acc:10303313... [more]
jph31.669e-5332.15junctophilin 3 [Source:NCBI gene;Acc:103038422][more]
jph33.100e-5332.15junctophilin 3 [Source:NCBI gene;Acc:103038422][more]
jph23.718e-5232.26junctophilin-2 [Source:NCBI gene;Acc:103043867][more]
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BLAST of Junctophilin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000009496.11.354e-2228.18pep scaffold:Pmarinus_7.0:GL480437:14153:18284:1 g... [more]
RSPH10B21.494e-746.43radial spoke head 10 homolog B2 [Source:HGNC Symbo... [more]
RSPH10B23.393e-746.43radial spoke head 10 homolog B2 [Source:HGNC Symbo... [more]
ENSPMAT00000003398.11.496e-633.73pep scaffold:Pmarinus_7.0:GL476560:333524:339285:-... [more]
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BLAST of Junctophilin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Junctophilin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO415628.091e-3528.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411707.540e-739.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO336391.262e-643.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306446.440e-637.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO290677.541e-641.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Junctophilin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
jph1a5.036e-5833.41junctophilin 1 [Source:NCBI gene;Acc:101173340][more]
jph32.290e-5733.93junctophilin 3 [Source:NCBI gene;Acc:101163737][more]
jph31.340e-5533.40junctophilin 3 [Source:NCBI gene;Acc:101163737][more]
jph26.886e-5531.59junctophilin 2 [Source:NCBI gene;Acc:101175160][more]
jph21.535e-5432.09junctophilin 2 [Source:NCBI gene;Acc:101175160][more]
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BLAST of Junctophilin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000065993.10.000e+099.78SMESG000065993.1[more]
SMESG000001306.11.967e-8126.94SMESG000001306.1[more]
SMESG000004402.17.425e-5229.90SMESG000004402.1[more]
SMESG000053274.14.260e-643.86SMESG000053274.1[more]
SMESG000011788.16.120e-641.07SMESG000011788.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031366 ID=SMED30031366|Name=Junctophilin|organism=Schmidtea mediterranea sexual|type=transcript|length=3422bp
CTTGAATATTGATTGATCATGTCAATGTATCTACAGTGCTGGTGCGTGTA
TACACGCAGATCAAGCTTGTATAGTGGATGTAAAACTGGGAAAAGTTGTC
GGGAAAATATTAACTATTTTGCAGAGTACCCAGTGTAACACAAAACTTTC
GATAGATTTTCTTTGGAATATCCTGGAAAATTTTTTTTACGAATTTCTGT
TTTTCTTTGTATTTGGAAGAAGAAAATAACAGGAATTTGAATTCAACTTA
TTGCCGTAATCATTCTTTTGTCTTGTGTCTAAGTTGAATATTCCATGCAC
TTCTGGATTTTTGTCTAGAGGATCTCGGATTATGGACGGCGTACCAGAAG
AAGTCTACAGTCAACTTCCGGCTGGTAGATATGAATTCAAAGACAGTGGA
ATTTATATTGGTGAATGGCTGAACGAAAAAGCTGTTGGTATTGGATTGCT
AACAAAAGACAAAAGCCAAGGAGAGTTCACAGGATTATGGAATTCGGGAT
CGGAAAAGTGTGGAGTTTTTCTTTGGCCAAGTGCTCCAGGAGCAATGTAC
GAAGGAGAATGGGCAAACAGCAAAAGAGATGGCTATGGGATTTTTATTAA
AGAAGATTGGATTGTAATGGGAAAATTCCAAGAAGGCTTTATTACACTGG
GAGTGAAAACTAAAGAAAAGTCAATTGGTAAATTTGAGGGTGAATTTGAA
GATGGCTGTCCGGTCTTTGGAATGGAAACTTATGCAGATGGAGGAACATA
TTGTGGTGATTATAAAAGTGGCCTCAGAGAAGGTTTGGGAGTCAGAACAT
CAATTCCATATGGGGAGATTTTTGCTTTTTTACCGGAAGAAAAACATTTG
CTTTTAAAAAGTGCAACAGATGAAAATAGCACCAACCTCTCATTCACCAG
CAACCACGTTGATAAAAATGGCAGTGCAAGTAAATTACCAAATAAATTCA
AGTGCGGATTTGTTCTAAGTGGGAAAAAAAGTGATTTATTGATTAAAAAA
TTGAGGCACATAAATGCGTGTAAAAAACATCAGAAAGGACTGAAAAGGTC
TAAATCACTAACTTCAATATTTAGTGCTTTGACGAAAAAGGAATTATATA
ACACAAAAAACATTCACAAAAATCACTTTGGCACCATTTCAGTGTATAGT
GTTCCAGGAAATGCATCTCCGAAATCTTTCCATTCATCTTTAACTTTCAA
TACAATCCAATCTATAGCCACCATGGATATGTCAGCTGGTGACACAATTG
CTCCCGATGTTTTTGAAACTTATTCTGGAGAATGGGTACAAGACCAAAGG
CACGGATTTGGTGTGTGTGAAAGAAGTGATGGGGTTATTTATGAAGGAGG
TTGGCTTAACAATAAACGCCATGGATTCGGGATAACTAAATTTTCTGACG
GAAGTTTCGAAGAAGGACAATACCAGAATGGAAAATTGATATTTCTCTGG
ACAAAAAGAAATCCGATCTTTTTTCTTCATTCTTTTCGAATGGGCTTACA
CATTAAAAAATCCGTTAAACAAGCCCGTAACGCATCTAAAAAAGCACAGG
AAAAAGATATGGATTGTCGTAAAAAATTAACTGAGATACGTGAAACCGTT
AAAAAAGCCAAGGAAGCAGCAGCATTAGCCCGAGAGTATTCATTGGAGAC
GCGCCAATTAGTAAAGGAAATGTATCCAGACTATGAACAACCAGGTATTC
GAATATTGACCGACATTGTCAGAATGATGAGAGTAACGAAAAGAGGTCAG
AAATCCTTCGAATCAATGTTACAAGCGGCGATAGACGTTGTTGAAGGTAG
AGGGGTACCCGAAATGATAAGCACTAATGATAATCTGACTGTTAACTACA
ATAAAGATAACTTTTTATTGGTGGATGCAGATGGAGAACATAGAGCTAGC
CGACACGGTAGTTTTAGAAGATCTAAAAAATTGTCCACACAGAATATATC
AAAAGAAATTCATCAGAAGCAAGCAAACAAACCAACAATAGAAATTAATC
ATTCTAGCATGCCAATAAAAAGAATTGAGTCTCAAAATTGTCCTGAGGAT
CCAAAACTTCCACATAAATTAAATCAGTTGGAATCGATACAACCTATAAC
ATTTCATCCTATTCAACAGTCATCAAAATTTGATACGATTAAATTGCAAG
AAACTCCAATTTTAAGAGTGCACGAATCTCCGGTAGATTTTCCAAAAGCT
CAAATAGTCATAGATAAAGTGTCAGATGCTGTACCATTCGAATGTGAAAC
TCCGATAAAAGAAATAGAAGAAATTGAGGAAGAAGTTTATGTGCCAGTCG
GTAATATCATGGCCACATCGCGTATCCCAAGTGAAACATTGTCCTCCATC
ATTTCATCCAATACTCACATTGATTATTTCAACCATTATTCTCAATCAAA
CGCAGATCAAAGTGAAAAGATTTTAAAATCAAAAATATATTCCATGAACT
CCAGTTCTCCTAATTCCAATATAAATAATCCTAGGAGGTTTACTGTTCCA
GAAATAATGACTCAAGAACCGGTTCATCCTACTCCAGTTACTAGTATTCT
CCGAGATTTGCAAGAGGAAGTTGAAGATGAAAACAGTGAATTTTCCGATA
CAATGATCTTAATGGATGGCGGAATTAGGAAACGAGTATCACCAGTCCCA
GTGAACCACATCAAATCACGAACAGAGTCCAAAATAACTCTGAATCAACC
GCAAGATGGCTTAAGACCTTTACCGATGATTTTCAATTTTACATCTCAAC
TCAATTTAAGCAAGGATTTACAAGAAGGTAGTTTACCTGACGTTTCAGCA
ACGAAGCGCATGTGTGGCATTCCAAGAGAGGAAGTTATTCGATTAGGTGA
AGAATATCAACATGCCATTGAATTAGATAAACAAAAATTAAAACAGGGAG
TTTTTGTGATCAGATTTTATAAGCTAGGGGACTGGTTGAGAGACCATGCT
GTTAGCTTAGTGGTGATATTTATCAACTTGTGTCTTCTCTATTTTTTCAT
AGCCATCATCAAGGATTACAAGATATCCTGATCTCCAGTCAACCGGGCGG
CATTTGATTGTGTACTAATTAGCACTAGTGTAGATAATCTGTAAATACCT
CTCTTTATCCATCTAATCGCAATTATAATTTTTCTAGAAATTATTATCTG
ACTGAGTTATCAGATTTTGAGAATATTATTTCTGTTTTATTGAATTATTA
TTTGTTTTCATGATATCTATATAATTTATATATTTGATTTTGTTGATCAT
TTGTCAATGGAATGTTGAAAGACAAGAAAGTATTATCAAATATTATTTTC
TTGTGTCATTGATGAAACCGATGATCAGTTGATTGTATAATTTTCGATGC
GGCTTTCATTGAGATTTTCAGATTTTGCCCTTTTGTTATTTGTTGAGAAA
TACATGTCAGTTTTTATTGTTG
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protein sequence of SMED30031366-orf-1

>SMED30031366-orf-1 ID=SMED30031366-orf-1|Name=SMED30031366-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=900bp
MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFT
GLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQ
EGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLRE
GLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSAS
KLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSAL
TKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDM
SAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFG
ITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARN
ASKKAQEKDMDCRKKLTEIRETVKKAKEAAALAREYSLETRQLVKEMYPD
YEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTND
NLTVNYNKDNFLLVDADGEHRASRHGSFRRSKKLSTQNISKEIHQKQANK
PTIEINHSSMPIKRIESQNCPEDPKLPHKLNQLESIQPITFHPIQQSSKF
DTIKLQETPILRVHESPVDFPKAQIVIDKVSDAVPFECETPIKEIEEIEE
EVYVPVGNIMATSRIPSETLSSIISSNTHIDYFNHYSQSNADQSEKILKS
KIYSMNSSSPNSNINNPRRFTVPEIMTQEPVHPTPVTSILRDLQEEVEDE
NSEFSDTMILMDGGIRKRVSPVPVNHIKSRTESKITLNQPQDGLRPLPMI
FNFTSQLNLSKDLQEGSLPDVSATKRMCGIPREEVIRLGEEYQHAIELDK
QKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIKDYKIS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0030314junctional membrane complex
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR017191Junctophilin
IPR003409MORN
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003409MORN motifSMARTSM00698morncoord: 71..92
e-value: 0.0091
score: 25.2
coord: 312..333
e-value: 1.3E-4
score: 31.3
coord: 335..356
e-value: 0.011
score: 25.0
coord: 23..44
e-value: 27.0
score: 3.3
coord: 138..159
e-value: 1.3
score: 13.3
IPR003409MORN motifPFAMPF02493MORNcoord: 314..334
e-value: 6.3E-6
score: 25.8
coord: 140..156
e-value: 0.19
score: 11.7
coord: 73..92
e-value: 0.0022
score: 17.8
coord: 337..358
e-value: 2.8E-5
score: 23.8
NoneNo IPR availableGENE3DG3DSA:2.20.110.10coord: 315..378
e-value: 8.2E-11
score: 43.9
NoneNo IPR availablePANTHERPTHR23085:SF16GH28348Pcoord: 14..892
NoneNo IPR availableSUPERFAMILYSSF82185Histone H3 K4-specific methyltransferase SET7/9 N-terminal domaincoord: 313..374
NoneNo IPR availableSUPERFAMILYSSF82185Histone H3 K4-specific methyltransferase SET7/9 N-terminal domaincoord: 15..102
NoneNo IPR availableSUPERFAMILYSSF82185Histone H3 K4-specific methyltransferase SET7/9 N-terminal domaincoord: 118..156
NoneNo IPR availableTMHMMTMhelixcoord: 871..893
IPR017191JunctophilinPANTHERPTHR23085FAMILY NOT NAMEDcoord: 14..892