Junctophilin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031366 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Junctophilin vs. Ensembl Human
Match: JPH3 (junctophilin 3 [Source:HGNC Symbol;Acc:HGNC:14203]) HSP 1 Score: 203.756 bits (517), Expect = 6.244e-54 Identity = 147/445 (33.03%), Postives = 230/445 (51.69%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQ 1690 GR+ F D G Y G W + KA G G+ T K QGE+TG W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + K+EG + +G +G ETY+DGGTY G + G+R+G GVR S+PYG + A + + L S S + + T+ H D + + + P + GFVL ++K + + GLK +S+S +S+ S +K+ + ++ G +V S + HS+++ ++ +A ++ D I ETY GEW D+R GFGV +RSDG+ YEG W +N+RHG+G F DG+ EEG+Y+ I + KR + L + ++ + ++V+ A A+ A++K + + R + A AA A+E + R KE P ++ Sbjct: 4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVI---RSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN--ILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQH 425
BLAST of Junctophilin vs. Ensembl Human
Match: JPH2 (junctophilin 2 [Source:HGNC Symbol;Acc:HGNC:14202]) HSP 1 Score: 197.593 bits (501), Expect = 3.815e-52 Identity = 153/463 (33.05%), Postives = 224/463 (48.38%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYG-EIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIV 1720 GR++F D G Y G W KA G GL T K QGE++G WN G E GV+ WPS G +EG W+ KR G GI K W+ G++ GF G++ S K+EG + +G +G ETYADGGTY G + +G+R G GVR S+PYG + P L + N T + +G A P + GF LS + + Q+G L+R++S TS+ S ++ + + AS + +SL + A I ETY GEW D+R GFGV ERS G+ YEG WL+N RHG+G T DG EEG+Y++ L+ +R + L S ++ ++ SV+ A+ A+ A++K + + + + A++AA A + S R L +E+ PD+ QPG R+L +I+ Sbjct: 3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGL--FQRGALLGKLRRAESRTSVGSQRSRVSFLKS--------------DLSSGASDAASTASLGEAAEGADEAAPFEA--DIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRR--MLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEIL 443
BLAST of Junctophilin vs. Ensembl Human
Match: JPH1 (junctophilin 1 [Source:HGNC Symbol;Acc:HGNC:14201]) HSP 1 Score: 192.2 bits (487), Expect = 1.402e-50 Identity = 145/451 (32.15%), Postives = 212/451 (47.01%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINA--CKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W KA G G+ T K QGE++G W+ G E G + WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + ++EG + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S H + S P + GFVL+ H +A K + GL R SL + + + + ++ + SS N+ S +D D + ETY GEW D+R+GFGV ERS+G+ YEG W NNKRHG+G T F DGS EEG+Y+N I + R + + + + ++++ A+ A+ A+ K + R A +AA AR+ R + +E+ PD+ QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPS--GNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQSNGSVL---HDAAAAADS--PAGTRGGFVLN-----------FHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRI----------SSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN--ILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG 420
BLAST of Junctophilin vs. Ensembl Human
Match: JPH4 (junctophilin 4 [Source:HGNC Symbol;Acc:HGNC:20156]) HSP 1 Score: 179.489 bits (454), Expect = 1.593e-46 Identity = 130/451 (28.82%), Postives = 209/451 (46.34%), Query Frame = 2 Query: 368 PAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPI-FFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTD 1714 P G+++F D G Y+G W +A G G+ T +QGE++G W G E GVF P G Y+G W KR+G G+ K W G++ G + S ++ G ++DG +G ETY+DGGTY G +++G R G GVR S+PY + A L + L S + T D+ GS + + + GFVL+G + A +RS L+ + + + L + + ++ + + P + ++ I+ AT E Y+GEW D+R GFGV +RS+G+ YEG WL N+RHG+G T DGS EEG+Y+ +L+ R+ + L ++ + ++V+ AR A A+++ + + A A A E + + + +++ P E PG R D Sbjct: 3 PGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPG--GHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQA-ALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSPA---SGSRGGFVLAGPGDADGASSRKRTPAAGGF---FRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSAT--------------EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQD 430
BLAST of Junctophilin vs. Ensembl Human
Match: JPH4 (junctophilin 4 [Source:HGNC Symbol;Acc:HGNC:20156]) HSP 1 Score: 179.489 bits (454), Expect = 1.593e-46 Identity = 130/451 (28.82%), Postives = 209/451 (46.34%), Query Frame = 2 Query: 368 PAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPI-FFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTD 1714 P G+++F D G Y+G W +A G G+ T +QGE++G W G E GVF P G Y+G W KR+G G+ K W G++ G + S ++ G ++DG +G ETY+DGGTY G +++G R G GVR S+PY + A L + L S + T D+ GS + + + GFVL+G + A +RS L+ + + + L + + ++ + + P + ++ I+ AT E Y+GEW D+R GFGV +RS+G+ YEG WL N+RHG+G T DGS EEG+Y+ +L+ R+ + L ++ + ++V+ AR A A+++ + + A A A E + + + +++ P E PG R D Sbjct: 3 PGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPG--GHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQA-ALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSPA---SGSRGGFVLAGPGDADGASSRKRTPAAGGF---FRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSAT--------------EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQD 430
BLAST of Junctophilin vs. Ensembl Celegans
Match: jph-1 (JunctoPHilin [Source:UniProtKB/TrEMBL;Acc:Q22667]) HSP 1 Score: 212.231 bits (539), Expect = 3.660e-57 Identity = 161/530 (30.38%), Postives = 256/530 (48.30%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK----FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIA--TMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRIL-----------TDI------VRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL-TVNYNKDNFL 1867 + GR++F D G Y+G W KA G G+ T +++GE+ G W+ G E GV+ WPS G Y+G+W N KR G GI + W+ G++ +G+ GV+ S +++G F DG +G E Y D G+Y G + G+R G G+R S Y EK +S + +++ S S V++ +A + +K + GFVL S R + + +KR+ + S L K+ ++T +IH+ V S+ G S +S S+++ + S+ + + + ETY GEW D R GFGVCERSDG+ Y+G W NN + G+G+T F DG+ EEG+Y+N LI ++R + F+ + + +++++ A A+ AQ+K + + RE ++A A A + S R K+ P ++QPG R L TD+ R + T Q SFE L ++D+ E P N + N N NF+ Sbjct: 1 MNGGRFDFDDGGTYVGGWEEGKAHGHGVCTGPQAKGEYAGAWHYGFEVSGVYTWPS--GNTYQGQWQNGKRHGLGIEQRGRWLYKGEWTQGYKGRYGVRQSANSQARYQGTWSAGFHDG---YGTEIYVDSGSYQGQWLRGMRHGYGIRKSTTY---------EKAAKFRSKSQTHASLTSLRSGRVEEENAAEEHRHKEGLSGRGGFVLRANSS----APQRRRRSLSERSLAVKRT-----LLSGLRIKKQHSTGDIHQR------VASMTG--SLRSSGSTMSCTSEDSLHHHGLQQPEEEAVEESSIETYMGEWKNDMRSGFGVCERSDGLKYQGEWANNAKCGYGVTTFKDGTKEEGRYKNNILIAS-SRRKGVIFMRASKFREKLEQALGAASRAASIAQQKADIAASRTSTARERSEQASFIARQANDDSEVARIHAKQFDPSFKQPGTRRLLKDNNGGESFGTDLSDAISYSRHLSQTHSKQHSFEQTL--SVDMAEDMTPPSKAYHNHVMPNSNTNHVNFM 496
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0079861) HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54 Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561 GR++F+D G Y G W KA G G+ T K QG + G WN G E G ++WPS G+ YEG+W N +R G G+ I G++ ++G GV+ S K+EG ++DG G ETYADGG Y G ++ G R G G+RTS P+G L S + + S +S +NG+A+K+ K + GFVL+ K L ++ R+ K +KG L ++ +T ++ K GTI+ S+ S S+ S+LT N +S A+ M + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N LI K++ +F S ++ I ++ A+ A K A Q DM Sbjct: 49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0079860) HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54 Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561 GR++F+D G Y G W KA G G+ T K QG + G WN G E G ++WPS G+ YEG+W N +R G G+ I G++ ++G GV+ S K+EG ++DG G ETYADGG Y G ++ G R G G+RTS P+G L S + + S +S +NG+A+K+ K + GFVL+ K L ++ R+ K +KG L ++ +T ++ K GTI+ S+ S S+ S+LT N +S A+ M + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N LI K++ +F S ++ I ++ A+ A K A Q DM Sbjct: 49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0304056) HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54 Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561 GR++F+D G Y G W KA G G+ T K QG + G WN G E G ++WPS G+ YEG+W N +R G G+ I G++ ++G GV+ S K+EG ++DG G ETYADGG Y G ++ G R G G+RTS P+G L S + + S +S +NG+A+K+ K + GFVL+ K L ++ R+ K +KG L ++ +T ++ K GTI+ S+ S S+ S+LT N +S A+ M + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N LI K++ +F S ++ I ++ A+ A K A Q DM Sbjct: 49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430
BLAST of Junctophilin vs. Ensembl Fly
Match: jp (gene:FBgn0032129 transcript:FBtr0304057) HSP 1 Score: 207.223 bits (526), Expect = 3.165e-54 Identity = 148/415 (35.66%), Postives = 215/415 (51.81%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKF-QEGFI-TLGVKTKEKSIGKFEGE----FEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNK---FKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSF------HSSLTF--NTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKA-QEKDM 1561 GR++F+D G Y G W KA G G+ T K QG + G WN G E G ++WPS G+ YEG+W N +R G G+ I G++ ++G GV+ S K+EG ++DG G ETYADGG Y G ++ G R G G+RTS P+G L S + + S +S +NG+A+K+ K + GFVL+ K L ++ R+ K +KG L ++ +T ++ K GTI+ S+ S S+ S+LT N +S A+ M + + P V ETY GEW +D+R G GV ERSDG+ YEG W NN++HG+G+T F DG+ EEG+Y+N LI K++ +F S ++ I ++ A+ A K A Q DM Sbjct: 49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPS--GSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS---GCETYADGGKYQGQWQEGKRHGYGIRTSAPFG-------------LASHHRRKNLHASLSSLRSGENGNAAKMVEKAEEIRGGFVLTAKSDKLPVR--RNSLTDKTGKKGF---------LMNLKMRKQRSTGDLEKR--GTIASGSIRSTMSSASWISTGSEQSNLTTKSNHTESNASFTMED-EQLDPTVVETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH-LFLARSRKLRDRIAAALSSAQRALKMAMQRSDM 430
BLAST of Junctophilin vs. Ensembl Fly
Match: CG30429 (gene:FBgn0050429 transcript:FBtr0072450) HSP 1 Score: 52.373 bits (124), Expect = 1.142e-6 Identity = 24/63 (38.10%), Postives = 40/63 (63.49%), Query Frame = 2 Query: 1268 TYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQ----YQNGKLIF 1444 Y G+W++++RHG G+ +DG IY G W + RHG G+ +++G+ EG Y+NG+ +F Sbjct: 118 VYFGKWIKNRRHGLGIQWYNDGNIYAGEWETDFRHGLGVMFYANGNRYEGHFARGYKNGEGVF 180 HSP 2 Score: 51.2174 bits (121), Expect = 2.760e-6 Identity = 27/83 (32.53%), Postives = 41/83 (49.40%), Query Frame = 2 Query: 1178 FHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQ 1426 + N Q + +M G +V YSG W D + G G SDG +Y G W+ N+RHG GI ++DG+ G+++ Sbjct: 69 YEGDWVMNKRQGVGSMLRKRGT----EVQLIYSGRWYDDMKCGEGKQFYSDGCVYFGKWIKNRRHGLGIQWYNDGNIYAGEWE 147
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph1b (junctophilin 1b [Source:ZFIN;Acc:ZDB-GENE-060616-389]) HSP 1 Score: 209.534 bits (532), Expect = 1.810e-56 Identity = 146/446 (32.74%), Postives = 229/446 (51.35%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G + G W + KA G G+ T K QGE++G W++G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + ++EG + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S N S +H+ S P + GFVL+ ++ +KGL R SL F +L + ++++ + + + S +S+++F + +A M A D + E+Y GEW D+R+GFGV ERS+G+ YEG W+NNKRHG+G T F DG+ EEG+Y+N L+ K+ + L + + + ++V+ A AS A+ K + R + A +A+ A + S R + +++ P++ QPG Sbjct: 1 MTGGRFDFDDGGTFCGGWEDGKAHGHGICTGPKGQGEYSGSWSNGFEVVGVYTWPS--GNTYKGYWAQGKRHGLGVESKGRWLYRGEWSHGFKGRYGVRQSLNTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQS-NGSVLHDHM------SDSPAGTRGGFVLNFHSDSEVVSG---------KKKGLFRRGSL---FGSLKQLRKSDSRSSISSKRSSARSDATMSRISSSDANSTISFGDGE-VADEYMPAEDNVDATTTESYLGEWKNDKRNGFGVSERSNGMKYEGEWINNKRHGYGCTMFPDGTKEEGKYKNNVLVRGIKKQ--LIPLKNTKTKQKVDRAVEGAIRASAIARTKVEIATSRTAHARAKAEAADQASLSASQESDLARAVARDLSPNFHQPG 421
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph1b (junctophilin 1b [Source:ZFIN;Acc:ZDB-GENE-060616-389]) HSP 1 Score: 209.534 bits (532), Expect = 1.810e-56 Identity = 146/446 (32.74%), Postives = 229/446 (51.35%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G + G W + KA G G+ T K QGE++G W++G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + ++EG + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S N S +H+ S P + GFVL+ ++ +KGL R SL F +L + ++++ + + + S +S+++F + +A M A D + E+Y GEW D+R+GFGV ERS+G+ YEG W+NNKRHG+G T F DG+ EEG+Y+N L+ K+ + L + + + ++V+ A AS A+ K + R + A +A+ A + S R + +++ P++ QPG Sbjct: 1 MTGGRFDFDDGGTFCGGWEDGKAHGHGICTGPKGQGEYSGSWSNGFEVVGVYTWPS--GNTYKGYWAQGKRHGLGVESKGRWLYRGEWSHGFKGRYGVRQSLNTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQS-NGSVLHDHM------SDSPAGTRGGFVLNFHSDSEVVSG---------KKKGLFRRGSL---FGSLKQLRKSDSRSSISSKRSSARSDATMSRISSSDANSTISFGDGE-VADEYMPAEDNVDATTTESYLGEWKNDKRNGFGVSERSNGMKYEGEWINNKRHGYGCTMFPDGTKEEGKYKNNVLVRGIKKQ--LIPLKNTKTKQKVDRAVEGAIRASAIARTKVEIATSRTAHARAKAEAADQASLSASQESDLARAVARDLSPNFHQPG 421
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph1a (junctophilin 1a [Source:ZFIN;Acc:ZDB-GENE-040724-233]) HSP 1 Score: 202.601 bits (514), Expect = 3.968e-54 Identity = 148/469 (31.56%), Postives = 222/469 (47.33%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNL-SFTSNHVDKNGSASKLPNKFKCGFVL---------SGKKSDL-----LIKKLRHINACKKHQKGLKRSKSLTSIFS----ALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRIL 1708 + GR++F D G Y G W + KA G G+ T K QGE++G W+ G E GV+ WPS G Y+G W+ KR G G+ K W+ G++ GF GV+ + +++G + +G +G+ETY D GTY G + G+R G GVR S+PYG +++S + +L S SN + P + GFVL +GKK L L LR L++S S TSI S A + + + N + VP + +P H T E+Y GEW D+R+GFGV ERS+G+ YEG W+NNKRHG+G T F DG+ EEG+Y+N L+ R + L + + + ++V+ AR ++ A+ K + + R + A +AA A + S R + E+ P + QPG+ + Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPS--GNTYQGYWSQGKRHGLGVETKGKWLYRGEWSHGFKGRYGVRQSTNTPARYDGTWSNGLQDGYGVETYGDSGTYQGQWMGGMRHGYGVRQSVPYGMA---------TIIRSPLRTSLASLRSVQSNGAVLQDTVPDTPVGSRGGFVLNFHSDTEVVTGKKKGLFRRGSLFGSLRQ----------LRKSDSKTSISSKRSSARSDATMSRISSSDANSTISYGEGEVPDDYTPMEDHVDAT---------------------TTESYMGEWKNDKRNGFGVSERSNGLKYEGEWMNNKRHGYGCTIFPDGTKEEGKYKNNVLVR--GIRKQLIPLKNHKTKEKVDRAVEGARRSAAIARTKVEIAVSRTSHARTKSEAADQAALAACQESDLARAVACELSPSFHQPGLEYI 425
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph3 (junctophilin 3 [Source:ZFIN;Acc:ZDB-GENE-060503-415]) HSP 1 Score: 202.601 bits (514), Expect = 1.688e-53 Identity = 144/455 (31.65%), Postives = 213/455 (46.81%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSN-------HVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDT-IAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRI 1705 GR+ F D G Y G W KA G G+ T K QGE+ G W+ G E G++ WPS G ++G WA KR G GI K W+ G++ GF GV+ + GK+EG + +G +G ETY+DGGTY G + G+R G GVR S+PYG + A + + S E+S + + P + GFVL+ L+K + KGL R S+ S L ++ + ++ S S G ++ S S + ++ GD + E+Y+GEW D+R G GV RSDG+ Y+G WL NKRHG+G T F DG+ EEG+Y+ I + KR + L + ++ + ++V+ A A+ A++K + R A AA A+E R KE P ++ G R+ Sbjct: 4 GGRFNFDDGGSYCGGWEEGKAHGHGICTGPKGQGEYAGSWSHGFEVVGIYTWPS--GNTFQGTWAQGKRHGIGIENKGKWVYKGEWTHGFKGRYGVRESTGTSGKYEGTWNNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHSNGTALLTGDRAPVAGVGGSGVLVVGSPAVSRGGFVLTAHSEAELLKNKK---------KGLFRR----SLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGEGELPVGDDDVDATTTESYAGEWKNDKRTGCGVSRRSDGLQYQGEWLGNKRHGYGCTTFPDGTKEEGKYKQN--ILVSGKRKNLIPLRASKIREKVDRAVESADKAADIAKQKAEIALSRTAHARGKADAATAAAQKAQEECRLARITAKEFSPSFQHRGNRV 440
BLAST of Junctophilin vs. Ensembl Zebrafish
Match: jph2 (junctophilin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-9848]) HSP 1 Score: 202.216 bits (513), Expect = 2.473e-53 Identity = 146/458 (31.88%), Postives = 217/458 (47.38%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGL----------KRSKSLTSIFSALTKKELYNTKNIHKNHFG----TISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 GR+EF D G Y G W KA G G+ T K QGEF+G WN G E GV+ WPS G YEG W+ KR G G+ K WI G++ GF G + + S K+EG + +G +G ETYADGGT+ G + G+R G GVR S+PYG ++ L ++ ++ L V +AS L + + +A K + GL K+S S TS+ S +K T++ + TIS+ + F +++ D+ A T E Y GEW D+R G+G+ ERS G+ YEG WLNN+RHG+G T F +G EEG+Y N L+ K+ + L ++ +++S++ A+ A+ A++K + + A++AA A S R + +E+ P + QPG Sbjct: 3 GGRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEFSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVETKGHWIYKGEWTHGFKGRYGTRISQGSGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYGMAAVVHSPLRNSLSSLRSEHSNGTLLQQDVPVITTTNASGQETPVNLPMPLGPSRGGFALTLQVDPDAVKPKKSGLFRRGSFLGKLKKSDSRTSLSSQKSKISFLRTESALSSAASDANSTISLGES------EGEGEGHNFPPVEA----DIDATTT------EVYMGEWKNDKRSGYGISERSSGLKYEGEWLNNQRHGYGCTTFPEGGKEEGKYVNNMLVKSVKKK--MIQLKGTKIKQKVERSLEGAQRAAAIAKQKAEIANSRTAHAKSKGDAAEQAAVAANNESSIARVVARELSPSFHQPG 440
BLAST of Junctophilin vs. Ensembl Xenopus
Match: JPH3 (junctophilin 3 [Source:NCBI gene;Acc:105947054]) HSP 1 Score: 208.379 bits (529), Expect = 2.339e-55 Identity = 148/445 (33.26%), Postives = 218/445 (48.99%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINA--CKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSA-GDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQ 1690 GR+ F D G Y G W + KA G G+ T K QGE+ G W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + K+EG + +G +G ETY+DGGTY G + +G+R G GVR S+PYG + A + + L S S + + T+ H D + + S P + GFVL + H +A K +KG+ R SI S L ++ + ++ S S G ++ S S + ++S D I E Y GEW D+R GFGV +RSDG+ YEG W NNKRHG+G F DG+ EEG+Y++ L+ KR + L + ++ + ++V +A A++K + + R A AA A+E + R KE P ++ Sbjct: 4 GGRFNFDDGGSYCGGWQDGKAHGHGICTGPKGQGEYAGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGLGVESKGKWVYRGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWAAGIRHGYGVRQSVPYG-MAAVI---RSPLRTSINSLRSEHTNGTALHPDASCTVSGSPAVSRGGFVL-----------MAHSDAEILKNKKKGIFRR----SILSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDINSTISLGEGETELSVIEDDIDATTTEVYMGEWKHDKRSGFGVSQRSDGLKYEGEWANNKRHGYGCMTFPDGTKEEGKYKHNVLVS--GKRKNLIPLRASKIREKVDRAVDEAERVCNIAKQKAEIAASRTSHSRAKADAAATAALKAQEEAQIARISAKEFSPSFQH 425
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849]) HSP 1 Score: 202.216 bits (513), Expect = 9.145e-55 Identity = 144/450 (32.00%), Postives = 212/450 (47.11%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W + KA G G+ T K QGE++G W+ G E G + WPS G Y G WA KR G G+ K WI G++ GF GV+ + +++G + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S VD P + GFVL+ S+L+ K +KGL R SL + + + ++ + SS N+ S D D + ETY GEW D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N L+ R + + + + + ++++ A+ A+ A+ K + R A +A+ AR+ S R + +E+ P + QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVR--GIRKQLIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849]) HSP 1 Score: 203.756 bits (517), Expect = 1.595e-54 Identity = 144/450 (32.00%), Postives = 213/450 (47.33%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W + KA G G+ T K QGE++G W+ G E G + WPS G Y G WA KR G G+ K WI G++ GF GV+ + +++G + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S VD P + GFVL+ S+L+ K +KGL R SL + + + ++ + SS N+ S D D + ETY GEW D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N L+ K+ + + + + + ++++ A+ A+ A+ K + R A +A+ AR+ S R + +E+ P + QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVRGIRKQ--LIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849]) HSP 1 Score: 201.83 bits (512), Expect = 1.647e-54 Identity = 144/450 (32.00%), Postives = 212/450 (47.11%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W + KA G G+ T K QGE++G W+ G E G + WPS G Y G WA KR G G+ K WI G++ GF GV+ + +++G + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S VD P + GFVL+ S+L+ K +KGL R SL + + + ++ + SS N+ S D D + ETY GEW D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N L+ R + + + + + ++++ A+ A+ A+ K + R A +A+ AR+ S R + +E+ P + QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVR--GIRKQLIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418
BLAST of Junctophilin vs. Ensembl Xenopus
Match: ing2 (inhibitor of growth family member 2 [Source:Xenbase;Acc:XB-GENE-951849]) HSP 1 Score: 203.756 bits (517), Expect = 2.516e-54 Identity = 144/450 (32.00%), Postives = 213/450 (47.33%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W + KA G G+ T K QGE++G W+ G E G + WPS G Y G WA KR G G+ K WI G++ GF GV+ + +++G + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S VD P + GFVL+ S+L+ K +KGL R SL + + + ++ + SS N+ S D D + ETY GEW D+R GFGV ERS+G+ YEG WLNN+RHG+G T F DG+ EEG+Y+N L+ K+ + + + + + ++++ A+ A+ A+ K + R A +A+ AR+ S R + +E+ P + QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPS--GNTYLGYWAQGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIHSPLRTSLSSLRSEQSNGTVLHDIGVDS-------PVGSRGGFVLNFHSDSELMTGK----------KKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRI----------SSSDANSTISFGDGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGTKEEGKYKNNVLVRGIRKQ--LIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANAADQASQAARQESDIARAVARELSPSFHQPG 418
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph3 (junctophilin 3 [Source:MGI Symbol;Acc:MGI:1891497]) HSP 1 Score: 204.527 bits (519), Expect = 2.284e-54 Identity = 127/362 (35.08%), Postives = 193/362 (53.31%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441 GR+ F D G Y G W + KA G G+ T K QGE+TG W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + K+EG + +G +G ETY+DGGTY G + G+R+G GVR S+PYG + A + + S E++ + H D + + + P + GFVL ++K + + GLK +S+S +S+ S +K+ + ++ G +V S + HS+++ ++ +A ++ D I ETY GEW D+R GFGV +RSDG+ YEG W++N+RHG+G F DG+ EEG+Y+ L+ Sbjct: 4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHTNGAAL---HPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLV 344
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph3 (junctophilin 3 [Source:MGI Symbol;Acc:MGI:1891497]) HSP 1 Score: 204.527 bits (519), Expect = 2.284e-54 Identity = 127/362 (35.08%), Postives = 193/362 (53.31%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441 GR+ F D G Y G W + KA G G+ T K QGE+TG W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + K+EG + +G +G ETY+DGGTY G + G+R+G GVR S+PYG + A + + S E++ + H D + + + P + GFVL ++K + + GLK +S+S +S+ S +K+ + ++ G +V S + HS+++ ++ +A ++ D I ETY GEW D+R GFGV +RSDG+ YEG W++N+RHG+G F DG+ EEG+Y+ L+ Sbjct: 4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHTNGAAL---HPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLV 344
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph2 (junctophilin 2 [Source:MGI Symbol;Acc:MGI:1891496]) HSP 1 Score: 197.208 bits (500), Expect = 3.422e-52 Identity = 162/501 (32.34%), Postives = 239/501 (47.70%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL 1837 GR++F D G Y G W KA G GL T K QGE++G WN G E GV+ WPS G +EG W+ KR G GI K W+ G++ GF G++ S K+EG + +G +G ETYADGGTY G + +G+R G GVR S+PYG + + L S E+S N + + +G P + GF L+ L+ +G L+RS+S TS+ S ++ ++ + AS + SL + I ETY GEW D+R GFGV ERS G+ YEG WL+N RHG+G T DG EEG+Y++ L+ TKR + L S ++ ++ V+ A+ A+ A++K + + + + A++AA A + S R L KE+ PD+ QPG R+L +I+ ++ ES+L+ + G G+PE + L Sbjct: 3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYG-MAVVVRSPLRTSLSSLRSEHS-NGTVAPDSPAADGPMLPSPPVPRGGFALT------LLATAEAARPQGLFTRGTLLGRLRRSESRTSLGSQRSRLSFLKSE--------------LSSGASDAASTGSLA-EGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSSKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEIL----------ENSESLLEPPERGL-GTGLPERPRESPQL 465
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph2 (junctophilin 2 [Source:MGI Symbol;Acc:MGI:1891496]) HSP 1 Score: 197.208 bits (500), Expect = 3.422e-52 Identity = 162/501 (32.34%), Postives = 239/501 (47.70%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL 1837 GR++F D G Y G W KA G GL T K QGE++G WN G E GV+ WPS G +EG W+ KR G GI K W+ G++ GF G++ S K+EG + +G +G ETYADGGTY G + +G+R G GVR S+PYG + + L S E+S N + + +G P + GF L+ L+ +G L+RS+S TS+ S ++ ++ + AS + SL + I ETY GEW D+R GFGV ERS G+ YEG WL+N RHG+G T DG EEG+Y++ L+ TKR + L S ++ ++ V+ A+ A+ A++K + + + + A++AA A + S R L KE+ PD+ QPG R+L +I+ ++ ES+L+ + G G+PE + L Sbjct: 3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYG-MAVVVRSPLRTSLSSLRSEHS-NGTVAPDSPAADGPMLPSPPVPRGGFALT------LLATAEAARPQGLFTRGTLLGRLRRSESRTSLGSQRSRLSFLKSE--------------LSSGASDAASTGSLA-EGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSSKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEIL----------ENSESLLEPPERGL-GTGLPERPRESPQL 465
BLAST of Junctophilin vs. Ensembl Mouse
Match: Jph1 (junctophilin 1 [Source:MGI Symbol;Acc:MGI:1891495]) HSP 1 Score: 196.052 bits (497), Expect = 6.037e-52 Identity = 144/449 (32.07%), Postives = 211/449 (46.99%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W KA G G+ T K QGE++G W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + ++EG + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S S P + GFVL+ L KK + GL R SL + + + + ++ + SS N+ S +D D + ETY GEW D+R+GFG+ ERS+G+ YEG W NNKRHG+G T F DGS EEG+Y+N I + R + + + + + ++++ A+ A+ A+ K + R A +AA AR+ R + +E+ PD+ QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPS--GNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADS----PAGTRGGFVLNFHADTELGKK----------KGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRI----------SSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN--ILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG 420
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q9ET77|JPH3_MOUSE (Junctophilin-3 OS=Mus musculus OX=10090 GN=Jph3 PE=1 SV=1) HSP 1 Score: 204.527 bits (519), Expect = 1.597e-53 Identity = 127/362 (35.08%), Postives = 193/362 (53.31%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441 GR+ F D G Y G W + KA G G+ T K QGE+TG W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + K+EG + +G +G ETY+DGGTY G + G+R+G GVR S+PYG + A + + S E++ + H D + + + P + GFVL ++K + + GLK +S+S +S+ S +K+ + ++ G +V S + HS+++ ++ +A ++ D I ETY GEW D+R GFGV +RSDG+ YEG W++N+RHG+G F DG+ EEG+Y+ L+ Sbjct: 4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVIRSPLRTSINSLRSEHTNGAAL---HPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLV 344
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q9GKY7|JPH2_RABIT (Junctophilin-2 OS=Oryctolagus cuniculus OX=9986 GN=JPH2 PE=2 SV=1) HSP 1 Score: 203.371 bits (516), Expect = 2.055e-53 Identity = 158/479 (32.99%), Postives = 225/479 (46.97%), Query Frame = 2 Query: 374 GRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYG-EIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----------LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAG----DTIAP-------DVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIV 1720 GR++F D G Y G W KA G GL T K QGE++G WN G E GV+ WPS G +EG W+ KR G GI K W+ G++ GF G + S K+EG + +G +G ETYADGGTY G + +G+R G GVR S+PYG + P L + N T + +G A P + GF LS L + A + + G L+R++S TS+ S ++ S L+ + +T + G D AP ETY GEW D+R GFGV ERS G+ YEG WL+N RHG+G T DG EEG+Y++ L+ TKR + L S ++ ++ SV+ A+ A+ A++K + + R + A++AA A + S R L +E+ PD+ QPG R+L +I+ Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGTRQSTSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPAADGPALPSPAIPRGGFALS---------LLANAEAARAPKGGGLFPRGALLGKLRRAESRTSVGSQRSRVSF---------------------------LKSDLSSGASDAASTASLGEGAEGADDAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAVSRTSHARAKAEAAEQAALAANQESNIARSLARELAPDFYQPGPEYQKRRLLQEIL 442
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q8WXH2|JPH3_HUMAN (Junctophilin-3 OS=Homo sapiens OX=9606 GN=JPH3 PE=1 SV=2) HSP 1 Score: 203.756 bits (517), Expect = 2.999e-53 Identity = 147/445 (33.03%), Postives = 230/445 (51.69%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQS-IATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQ 1690 GR+ F D G Y G W + KA G G+ T K QGE+TG W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + K+EG + +G +G ETY+DGGTY G + G+R+G GVR S+PYG + A + + L S S + + T+ H D + + + P + GFVL ++K + + GLK +S+S +S+ S +K+ + ++ G +V S + HS+++ ++ +A ++ D I ETY GEW D+R GFGV +RSDG+ YEG W +N+RHG+G F DG+ EEG+Y+ I + KR + L + ++ + ++V+ A A+ A++K + + R + A AA A+E + R KE P ++ Sbjct: 4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYG-MAAVI---RSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSF------RSEAGMSTVSSTASD-----IHSTISLGEAEAELAVIE----DDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN--ILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQH 425
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q2PS20|JPH2_RAT (Junctophilin-2 OS=Rattus norvegicus OX=10116 GN=Jph2 PE=1 SV=1) HSP 1 Score: 201.83 bits (512), Expect = 6.777e-53 Identity = 164/501 (32.73%), Postives = 240/501 (47.90%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNL 1837 GR++F D G Y G W KA G GL T K QGE++G WN G E GV+ WPS G +EG W+ KR G GI K W+ G++ GF G++ S K+EG + +G +G ETYADGGTY G + +G+R G GVR S+PYG + + L S E+S N + + +G LP + GF LS L+ +G L+RS+S TS+ S ++ ++ + AS + SL + I ETY GEW D+R GFGV ERS G+ YEG WL+N RHG+G T DG EEG+Y++ L+ TKR + L S ++ ++ V+ A+ A+ A++K + + + + A++AA A + S R L KE+ PD+ QPG R+L +I+ ++ ES+L+ + G G+PE + L Sbjct: 3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYG-MAVVVRSPLRTSLSSLRSEHS-NGTVAPDSPAADGPTLPLPPVPRGGFALS------LLATAEAARPPGLFTRGALLGRLRRSESRTSLGSQRSRLSFLKSE--------------LSSGASDAASTGSLA-EGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVLV-KGTKRR-VLPLKSNKVRQKVEHGVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEIL----------ENSESLLEPR-ERGPGTGLPERPRESPQL 465
BLAST of Junctophilin vs. UniProt/SwissProt
Match: sp|Q9BR39|JPH2_HUMAN (Junctophilin-2 OS=Homo sapiens OX=9606 GN=JPH2 PE=1 SV=2) HSP 1 Score: 197.593 bits (501), Expect = 1.832e-51 Identity = 153/463 (33.05%), Postives = 224/463 (48.38%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYG-EIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKG-----LKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIV 1720 GR++F D G Y G W KA G GL T K QGE++G WN G E GV+ WPS G +EG W+ KR G GI K W+ G++ GF G++ S K+EG + +G +G ETYADGGTY G + +G+R G GVR S+PYG + P L + N T + +G A P + GF LS + + Q+G L+R++S TS+ S ++ + + AS + +SL + A I ETY GEW D+R GFGV ERS G+ YEG WL+N RHG+G T DG EEG+Y++ L+ +R + L S ++ ++ SV+ A+ A+ A++K + + + + A++AA A + S R L +E+ PD+ QPG R+L +I+ Sbjct: 3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPS--GNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGL--FQRGALLGKLRRAESRTSVGSQRSRVSFLKS--------------DLSSGASDAASTASLGEAAEGADEAAPFEA--DIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRR--MLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEIL 443
BLAST of Junctophilin vs. TrEMBL
Match: A0A183ALC7 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS7762 PE=4 SV=1) HSP 1 Score: 486.878 bits (1252), Expect = 4.191e-155 Identity = 254/547 (46.44%), Postives = 356/547 (65.08%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLP----------------------------EEKHLL---------LKSATDEN---STNLSFTSNHVDKNGSAS--------------KLPNKFKCGFVLSGKKSDLLIKKLRHI--NACKKHQKGLK-----------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798 LPAGRYEFKDSG+YIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWA+++R+G+G+F +EDW++MGKF E FI+LG+K KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+REGLGVRTSIPYGE+ F P LL L++A DEN + + + +++ +A+ ++ +KFKCGFVLS ++S+L++++ + NA G K R++SLT++F + +E +I G+A+ +S + T+ IQS + + D I P+ ET++G+W D RHG+GVCERSDGV YEG WL N+RHGFG T+F DG+ E+G+YQ GKL+FL W+K P L+++ + + SVK+AR +++A+ + + R+ L + V+++K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MR T+RG K+FES L AA++V+ G Sbjct: 36 LPAGRYEFKDSGLYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWAHNRRNGHGVFTREDWVIMGKFDEDFISLGIKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIREGLGVRTSIPYGEVINFFPEEAALAAELLLQAKREAANRAAELTRDGRRGSLLSQRSGDVAELENADDENPGTDEDEPYLTRKLNQTQAAANSTTPAITGGLRDLRMSSKFKCGFVLSSQRSELVLRRQNKLVGNAPPAAGTGRKSREAGARSGRTRARSLTNLFGRSSSRE-------------SIPRMKRQGSANDRS--NLTTYKPIQSESVFTLDQDDAIDPETVETFAGQWESDTRHGYGVCERSDGVTYEGQWLKNQRHGFGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHLLLYNYHIMREVAASVKRARVIAEQARMRAAEARENLENVHAAVERSKQAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRATRRGNKAFESALDAALEVIAG 567
BLAST of Junctophilin vs. TrEMBL
Match: A0A3R7GDK8 (Junctophilin-2 OS=Clonorchis sinensis OX=79923 GN=JPH2 PE=4 SV=1) HSP 1 Score: 494.197 bits (1271), Expect = 1.964e-152 Identity = 255/534 (47.75%), Postives = 354/534 (66.29%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHL----------LLKSATDENST---------------------NLS-------FTSNHVDKNGSAS--------KLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798 LPAGRYEFKD+GIYIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWAN++R+G+GIF +EDW++MGKF + FI++GVK KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+R+GLGVRTSIPYGE+ F PEE L L++A N + NL F+ G AS ++ KF+CGFVLS ++S+L+ ++ ++ K ++G R++SLT++F+ +E +IH+ + G+AS ++ + T +S+ T+D D I P+ ET++G+W D RHG+GVCERSDGV YEG W N+RHG+G T+F DG+ E+G+YQ GKL+FL W+K P L+++ + + + SVK+AR +++A+ + + R+ L + V+ +K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MRVTKRG +FES L+AA V+ G Sbjct: 12 LPAGRYEFKDAGIYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWANNRRNGHGIFTREDWVIMGKFVDDFISVGVKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIRDGLGVRTSIPYGEVINFFPEEAALAAEMKAKRRAALEAANTINESQKLGRHGSLLSQRSGEAAEMENLEAPEEDEPFSGRRATPTGGASNTAGLRELRMSCKFRCGFVLSSQRSELVQRRQDKLSGVSKPRRGRDVVPRSGHHRTRSLTNLFTRSLSRE-----SIHR--------FKRQGSASERTTYGKADETTPESVFTLDQE--DAIDPETVETFAGQWENDSRHGYGVCERSDGVTYEGQWFKNQRHGYGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHMLLYNYHIKMGVGSSVKRARVIAEQARLRATEARENLENVHMIVELSKKAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRVTKRGNLAFESALEAAQGVLAG 530
BLAST of Junctophilin vs. TrEMBL
Match: A0A4S2MK81 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000339 PE=4 SV=1) HSP 1 Score: 493.426 bits (1269), Expect = 3.079e-152 Identity = 253/534 (47.38%), Postives = 354/534 (66.29%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLK-SATDENSTNLSFTSNHVDK-----------NGSASKLPN----------------------------------KFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798 LPAGRYEFKD+GIYIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWAN++R+G+GIF +EDW++MGKF + FI++GVK KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+R+GLGVRTSIPYGE+ F PEE L + A + + T N K +G A+++ N KF+CGFVLS ++S+L+ ++ ++ K ++G R++SLT++F+ +E +IH+ + G+AS ++ + + T +S+ T+D D I P+ ET++G+W D RHG+GVCERSDGV YEG W N+RHG+G T+F DG+ E+G+YQ GKL+FL W+K P L+++ + + + SVK+AR +++A+ + + R+ L + V+ +K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MRVTKRG +FES L+AA V+ G Sbjct: 12 LPAGRYEFKDAGIYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWANNRRNGHGIFTREDWVIMGKFVDDFISMGVKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIRDGLGVRTSIPYGEVINFFPEEAALAAEMKAKRRAALEAANTVNESQKLGRRGSLLSQRSGEAAEMENLEAPEEDEPFSGRRATPTGGATTTAGLRELRMSCKFRCGFVLSSQRSELVQRRQDKLSGVSKPRRGRDVVPRSGHHRTRSLTNLFTRSLSRE-----SIHR--------FKRQGSASERTTYGKVDETTPESVFTLDQE--DAIDPETVETFAGQWENDSRHGYGVCERSDGVTYEGQWFKNQRHGYGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHMLLYNYHIKMGVGSSVKRARVIAEQARLRATEARENLENVHMIVELSKKAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRVTKRGNLAFESALEAAQGVLAG 530
BLAST of Junctophilin vs. TrEMBL
Match: G7YME1 (Junctophilin-2 OS=Clonorchis sinensis OX=79923 GN=CLF_112255 PE=4 SV=1) HSP 1 Score: 494.582 bits (1272), Expect = 1.801e-150 Identity = 255/534 (47.75%), Postives = 354/534 (66.29%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHL----------LLKSATDENST---------------------NLS-------FTSNHVDKNGSAS--------KLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLK--------RSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFL-WTK-RNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798 LPAGRYEFKD+GIYIGEWLNEKAVG+GL+TKDK QGE+TGLW++G EK GVFLWP+APGAMYEGEWAN++R+G+GIF +EDW++MGKF + FI++GVK KE SIG+FEGEFE+G P FG+ETYADGG+Y G+YK+G+R+GLGVRTSIPYGE+ F PEE L L++A N + NL F+ G AS ++ KF+CGFVLS ++S+L+ ++ ++ K ++G R++SLT++F+ +E +IH+ + G+AS ++ + T +S+ T+D D I P+ ET++G+W D RHG+GVCERSDGV YEG W N+RHG+G T+F DG+ E+G+YQ GKL+FL W+K P L+++ + + + SVK+AR +++A+ + + R+ L + V+ +K+AA LAR+YSLETR+LVKEMYPD+EQPGI+ L D+VR+MRVTKRG +FES L+AA V+ G Sbjct: 12 LPAGRYEFKDAGIYIGEWLNEKAVGLGLITKDKCQGEYTGLWDAGMEKSGVFLWPNAPGAMYEGEWANNRRNGHGIFTREDWVIMGKFVDDFISVGVKCKENSIGRFEGEFENGFPSFGVETYADGGSYAGEYKNGIRDGLGVRTSIPYGEVINFFPEEAALAAEMKAKRRAALEAANTINESQKLGRHGSLLSQRSGEAAEMENLEAPEEDEPFSGRRATPTGGASNTAGLRELRMSCKFRCGFVLSSQRSELVQRRQDKLSGVSKPRRGRDVVPRSGHHRTRSLTNLFTRSLSRE-----SIHR--------FKRQGSASERTTYGKADETTPESVFTLDQE--DAIDPETVETFAGQWENDSRHGYGVCERSDGVTYEGQWFKNQRHGYGQTRFQDGTCEQGRYQYGKLVFLSWSKGTKPHMLLYNYHIKMGVGSSVKRARVIAEQARLRATEARENLENVHMIVELSKKAAELARDYSLETRELVKEMYPDFEQPGIKYLDDMVRLMRVTKRGNLAFESALEAAQGVLAG 530
BLAST of Junctophilin vs. TrEMBL
Match: W6UC37 (Junctophilin-1 OS=Echinococcus granulosus OX=6210 GN=EGR_06401 PE=4 SV=1) HSP 1 Score: 440.654 bits (1132), Expect = 3.122e-133 Identity = 246/535 (45.98%), Postives = 330/535 (61.68%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPE-------------EKHLLLKSATDEN-STNLSFTSNHVDKNGSA--SKLPNKFKCGFVLSGKKSDL--------------LIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTIS--------------VYSVPGNAS---PKSFHSSL--TFNTIQSI-----ATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLW--TKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLT-EIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEG 1798 LPAGRYEF+D+GIYIGEWL+EKAVG+GL+TKDKSQGE+TGLW +GSEK GVFLWP+APGAMYEGEWA ++R+G+G+F +EDW++MGKF++ FIT+GVK K+ + GKFEG FE+G P FG+ETY D GTYCGDYK+G+REGLGVR SI YGE+ PE K L S N +SF +D A S N V+ G++ D RH NA + + L+S S L K L K+ N FG + +++ P PKS+ + +N+ S+ A D D IA D E YSGEW D RHG+GVCER+DG+ Y G W N+RHGFG T+F DG+FE+G+Y NGKL++L P L++ + ++K V +A A ++AQ+K ++ R++++ ++ + ++KAK AA+ AREYSLE R+LV+EMYPD+EQPGI+ L DIVRMMRVT++G +FE+ LQ+A DVV G Sbjct: 62 LPAGRYEFRDNGIYIGEWLDEKAVGLGLITKDKSQGEYTGLWEAGSEKSGVFLWPNAPGAMYEGEWAMNRRNGFGVFNREDWVIMGKFEDDFITMGVKGKDNAPGKFEGRFENGFPAFGVETYGDKGTYCGDYKNGIREGLGVRRSITYGEVLELYPEIKKASNSSKLEDLRKRGKLPSPLKINLDRRMSFDQGSIDVPCEAVWSSENNSDGVDGVMDGEECDPEPYTAPRDTTSYLECAMGHRHQNATYRLMVAQRCGFMLSSKRSELFIKRLNKLKHPRINPFGCTTPEAPERKRTQSLSMLFTYPEETMPTLPKSYVRQMKDLYNSSNSLPKIIPAENDTLELDLIADDTVEVYSGEWFSDARHGYGVCERTDGLAYYGQWFKNQRHGFGHTRFPDGTFEQGKYHNGKLVYLALPAGNKPHMVLYNRHVMQEVQKMVHRAMLAGEQAQKKAIEAREQVSMKVLDYIEKAKAAASCAREYSLEARELVREMYPDFEQPGIKYLEDIVRMMRVTRQGSPTFEAALQSAKDVVAG 596
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph1b (junctophilin-1 [Source:NCBI gene;Acc:103024555]) HSP 1 Score: 206.453 bits (524), Expect = 1.763e-55 Identity = 144/446 (32.29%), Postives = 219/446 (49.10%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W + KA G G+ T K QGE++G W+SG E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + ++EG + +G +G+ETY DGGTY G + G+R G GVR S+PYG + + L S E S D P + GFVL+ L R +KGL R SL F +L + ++++ + + + S +S+++F + A D + E Y GEW D+R+GFGV ERS+G+ YEG W NNKRHG+G T F DG+ EEG+Y+N L+ K+ + L + + + ++V+ A A+ A+ K + R + A +A+ A + S R + +++ P++ QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSSGFEVVGVYTWPS--GNTYQGHWAQGKRHGLGVESKGRWLYRGEWTHGFKGRYGVRQSLNTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWMGGMRHGYGVRQSVPYG-MATVIRSPLRTSLASLRSEQSNGSVLHERLTDS-------PAGTRGGFVLNFHSDSELGGPAR--------KKGLFRRGSL---FGSLKQLRKSDSRSSISSKRSSARSDATMSRISSSDANSTISFGEGEG-ADEYTPMEDNVDATTTEAYMGEWKNDKRNGFGVSERSNGMKYEGEWTNNKRHGYGCTMFPDGTREEGKYKNNVLVRGIKKQ--LIPLKNTKTKQKVDRAVEGAIRAAAIAKTKVEIATSRTAHARAKGEAADQASLSACQNSDVARAVARDLSPNFHQPG 422
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph1a (junctophilin-1-like [Source:NCBI gene;Acc:103033137]) HSP 1 Score: 201.06 bits (510), Expect = 8.446e-54 Identity = 147/447 (32.89%), Postives = 223/447 (49.89%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNL-SFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W + KA G G+ T + QGE+ G W+ G E GV+ WPS G Y+G W+ KR G G+ K W+ G++ GF GV+ + +++G + +G +G+ETYADGGTY G + G+R G GVR S+PYG ++++S + +L S SN V + + P + GFVL+ A K + GL R SL F +L ++L +++ S S ++ S S + M+ D + ETY GEW D+R+GFG+ ERS+G+ YEG WLNNKR+G+G T F DG+ EEG+Y+N L+ R I L + + ++++V+ AR + A+ K + T R + A +AA A S R + +E+ P + QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPQGQGEYAGAWSHGFEIVGVYTWPS--GNTYQGYWSQGKRHGLGVETKGRWMYRGEWSHGFKGRYGVRQGSNTPARYDGTWSNGLQDGYGVETYADGGTYQGQWMGGMRHGYGVRQSVPYGMA---------MVIRSPLRTSLASLRSVQSNGVVMPDTTGEQPVSTRGGFVLN-------FHSEAEAQAGGKKKPGLFRRGSL---FGSL--RQLRKSESKSSISSKRSSAMSRISSSDGNSSISYGEGEAQEEFLPME----DNVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWLNNKRNGYGCTIFPDGTREEGKYKNNVLVR--GIRKQIIPLKNPKTKEKVERAVEGARRGAAIARMKVEIATSRTTHARAKSEAADQAAVAAGHESDLARAVARELSPSFHQPG 418
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:103038422]) HSP 1 Score: 201.445 bits (511), Expect = 1.669e-53 Identity = 145/451 (32.15%), Postives = 215/451 (47.67%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNH------VDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDT-IAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 GR+ F D G Y G W KA G G+ T K QGE+ G W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + GK+EG + +G +G ETY+DGGTY G + G+R G G+R S+PYG + A + + S E+S + + GS P + GFVL+ L+K K KGL R S+ S L ++ + ++ S S G ++ S S + ++ AG+ + E+Y+GEW D+R G GV RSDG+ Y+G W+ NKRHG+G T F DG+ EEG+Y+ L+ KR + L + ++ + ++V+ A A+ A++K + R + A AA A+E R KE P ++ G Sbjct: 4 GGRFNFDDGGSYCGGWEEGKAHGHGICTGPKGQGEYAGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLENKGKWVYKGEWTHGFKGRYGVRESTGASGKYEGTWNNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGIRQSVPYG-MAAVIRSPLRTSINSLRSEHSNGTALLAGERAGVGPGVGPGSLVASPAVSRGGFVLTAHSEAELLKG--------KKNKGLFR----RSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGESELPAGEEDVDATATESYAGEWKNDKRTGCGVSRRSDGLCYQGEWMGNKRHGYGCTTFPDGTKEEGKYKQNVLVS--GKRKHLIPLRASKIREKVDRAVEGAEKAADIAKQKSEIALSRTAHARGKAEAAIAAAQKAQEECRLARVAAKEFSPSFQHRG 437
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:103038422]) HSP 1 Score: 201.83 bits (512), Expect = 3.100e-53 Identity = 145/451 (32.15%), Postives = 215/451 (47.67%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNH------VDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDT-IAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 GR+ F D G Y G W KA G G+ T K QGE+ G W+ G E GV+ WPS G Y+G WA KR G G+ K W+ G++ GF GV+ + GK+EG + +G +G ETY+DGGTY G + G+R G G+R S+PYG + A + + S E+S + + GS P + GFVL+ L+K K KGL R S+ S L ++ + ++ S S G ++ S S + ++ AG+ + E+Y+GEW D+R G GV RSDG+ Y+G W+ NKRHG+G T F DG+ EEG+Y+ L+ KR + L + ++ + ++V+ A A+ A++K + R + A AA A+E R KE P ++ G Sbjct: 4 GGRFNFDDGGSYCGGWEEGKAHGHGICTGPKGQGEYAGSWSHGFEVLGVYTWPS--GNTYQGTWAQGKRHGIGLENKGKWVYKGEWTHGFKGRYGVRESTGASGKYEGTWNNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGIRQSVPYG-MAAVIRSPLRTSINSLRSEHSNGTALLAGERAGVGPGVGPGSLVASPAVSRGGFVLTAHSEAELLKG--------KKNKGLFR----RSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGESELPAGEEDVDATATESYAGEWKNDKRTGCGVSRRSDGLCYQGEWMGNKRHGYGCTTFPDGTKEEGKYKQNVLVS--GKRKHLIPLRASKIREKVDRAVEGAEKAADIAKQKSEIALSRTAHARGKAEAAIAAAQKAQEECRLARVAAKEFSPSFQHRG 437
BLAST of Junctophilin vs. Ensembl Cavefish
Match: jph2 (junctophilin-2 [Source:NCBI gene;Acc:103043867]) HSP 1 Score: 199.134 bits (505), Expect = 3.718e-52 Identity = 150/465 (32.26%), Postives = 226/465 (48.60%), Query Frame = 2 Query: 374 GRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVD----KNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDV----FETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGI-----RILTDIVR 1723 GR+EF D G Y G W KA G G+ T K QGEF+G WN G E GV+ WPS G YEG W+ KR G G+ K W+ G++ GF G + S K+EG + +G +G ETYADGGT+ G + G+R G GVR S+PYG + A + L S E+S N + V N S + P+ G G L + + K +KGL R SL LTK E ++ + +S S + ++ T + +S + + D+ E Y GEW D+R G+G+ ERS G+ YEG WL+N+RHG+G T F++G EEG+Y + L+ K+ + L ++ +++SV+ A+ A+ A++K + + + + A +A+ A S R + +E+ P + QPG R+L +I + Sbjct: 4 GRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEFSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVETKGHWVYKGEWTHGFKGRYGSRVSLASGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYG-MAAVVRSPLRNSLTSLRSEHS-NGTLLQQDVPLITTTNASGQESPSPTPIGPSRGGFALTLHVDP----DQVKPKKKGLFRRGSL---LGKLTKSE---SRTSLSSQKSKLSFLRSDSALSSAASDANSTISLGESEGEAEGGEFPPVEADIDATTTEVYLGEWKNDKRSGYGISERSSGLKYEGEWLDNQRHGYGCTTFAEGGKEEGKYMHNMLVKAVKKK--LIQLKGTKIKQKVERSVEGAQRAAAIAKQKAEIANSRTSHAKSKGEAADQASHGANNESSIARVVARELSPSFYQPGPEYLKKRVLQEISK 452
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009496.1 (pep scaffold:Pmarinus_7.0:GL480437:14153:18284:1 gene:ENSPMAG00000008588.1 transcript:ENSPMAT00000009496.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 97.8265 bits (242), Expect = 1.354e-22 Identity = 82/291 (28.18%), Postives = 129/291 (44.33%), Query Frame = 2 Query: 743 GTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVD------KNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIAT----MDMSAG----------DTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEK 1555 GTY G + G+R G GVR S+PYG + + + L S E TN S ++G + + GFVL+G ++ Q+G K L + K + ++S + SF S + I S A+ + +S G D + + ETY+GEW D+R GFGV +RSDG+ YEG WL N+R+G+G T + DG EEG+Y+ G L KR + L + + ++++V+ A+ + A++K Sbjct: 1 GTYQGQWAGGMRHGYGVRNSVPYG-LASVVRSPLRTSLSSLRSEQ-TNGSIVGPVGGGAGGSLRSGDDAGSAVGSRGGFVLTG------------VHHSDSEQQGGKAGGKRGGGGLFRRGSLLGSLKFRRSDSKASLSSE----RSKRSSFRSEAGMSAISSAASDGTSLAVSLGEPETELFDSEDLVEANTTETYTGEWKGDKRSGFGVSQRSDGLRYEGEWLANRRNGYGRTSYPDGRSEEGKYRQGTLTR--GKRRSLVPLRASKTRAKVERAVEAAQRGATVAKQK 271
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: RSPH10B2 (radial spoke head 10 homolog B2 [Source:HGNC Symbol;Acc:HGNC:34385]) HSP 1 Score: 53.9138 bits (128), Expect = 1.494e-7 Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 2 Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFE-EGQYQNGK 1435 Y GEW + RHG+G+ G IYEG WLNN+RHG G ++ E GQ+++GK Sbjct: 64 YCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGK 119 HSP 2 Score: 48.9062 bits (115), Expect = 5.296e-6 Identity = 23/58 (39.66%), Postives = 33/58 (56.90%), Query Frame = 2 Query: 1262 FETYSGEWVQDQRHGFGVC--ERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQN 1429 F +YSG W +RHG G+ + Y G W +N RHG+GI ++ G+ EGQ+ N Sbjct: 36 FVSYSGHWYASERHGKGIVYYDEKRESWYCGEWHHNMRHGWGIRRYPSGNIYEGQWLN 93
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: RSPH10B2 (radial spoke head 10 homolog B2 [Source:HGNC Symbol;Acc:HGNC:34385]) HSP 1 Score: 52.7582 bits (125), Expect = 3.393e-7 Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 2 Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFE-EGQYQNGK 1435 Y GEW + RHG+G+ G IYEG WLNN+RHG G ++ E GQ+++GK Sbjct: 103 YCGEWHHNMRHGWGIRRYPSGNIYEGQWLNNERHGEGCMRWITLMQEYNGQWKHGK 158
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003398.1 (pep scaffold:Pmarinus_7.0:GL476560:333524:339285:-1 gene:ENSPMAG00000003108.1 transcript:ENSPMAT00000003398.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 47.7506 bits (112), Expect = 1.496e-6 Identity = 28/83 (33.73%), Postives = 45/83 (54.22%), Query Frame = 2 Query: 1265 ETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKL--IFLWTKRNPIFFLHSFRMGLHIK 1507 E Y GEW + +RHG G +DG Y G + N G G+ F DGS EG++ GK + ++++ + + F F+ G H++ Sbjct: 14 EEYQGEWKEGRRHGLGQLRFTDGTHYLGQFENGLFSGCGVLAFPDGSRFEGEFSQGKFHGVGVFSRSDGMMFEGEFKNG-HVE 95 HSP 2 Score: 45.4394 bits (106), Expect = 8.372e-6 Identity = 25/60 (41.67%), Postives = 36/60 (60.00%), Query Frame = 2 Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSF----EEGQYQNGKL 1438 + GE+ Q + HG GV RSDG+++EG + N G+G+ F DGS EG ++N KL Sbjct: 62 FEGEFSQGKFHGVGVFSRSDGMMFEGEFKNGHVEGYGLLTFPDGSHGLPRNEGIFENNKL 121
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO41562 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3X5]) HSP 1 Score: 137.502 bits (345), Expect = 8.091e-35 Identity = 113/401 (28.18%), Postives = 178/401 (44.39%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFA---FLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPI-FFLHSFRMGLHIKKSVKQARNASKKAQEK 1555 + GR++F+D G Y GEW N KA G G+ T K Q + G W++G E GV++WP+ G YEGEW KR G G+ + WI G++++GF +G++ G Y G + SGL+EG G+ E++A + + ++S S + S S+ N G + + +K ++ + + H S + E N N T SV S G+ S + SL ++ ++ + A + + P V E Y G+W D+RHG+G+ E SDG Y G W N RHG G+ + D S EG+++N L+ K+ PI + FR L + + + A+ AS A +K Sbjct: 1 MSGGRFDFEDGGTYCGEWRNGKAHGYGICTGPKGQARYEGSWHNGFELSGVYVWPN--GHRYEGEWYCGKRHGLGVEYRGKWIYQGEWEDGFKAR----------------------YGVQRSQSGARYEGSWTSGLQEGYGI-------EVYANGGYYYGQWKTGMRSGYGIRSAKRDPKVTITNYARSISRQSNAESNGVIPTKQK-----RQGGELPPAEPH--------------SPKSGSESDNASN-------TGSVNSTVGSGSTQLADGSL--DSTVAVTQTEPEA-EPVKP-VRELYKGDWKNDKRHGYGILEASDGYKYIGQWHENMRHGLGVACYPDSSKYEGEFENDNLVVDIKKKGPIKTLVTRFRQRLQV--ACEAAQQASDLAVQK 338
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO41170 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S530]) HSP 1 Score: 51.2174 bits (121), Expect = 7.540e-7 Identity = 22/56 (39.29%), Postives = 38/56 (67.86%), Query Frame = 2 Query: 1265 ETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNG 1432 E Y GEW D+R G+G SDG +YEG W ++K++G G+ + ++ + EG++++G Sbjct: 110 EYYEGEWYADKRSGWGRMYYSDGAVYEGEWYDDKQNGEGMLRLANENRYEGEWKDG 165 HSP 2 Score: 49.2914 bits (116), Expect = 2.983e-6 Identity = 24/55 (43.64%), Postives = 33/55 (60.00%), Query Frame = 2 Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGK 1435 YSG W D+RHG+G S YEG W +KR G+G +SDG+ EG++ + K Sbjct: 89 YSGGWKNDKRHGYGTNFYSPTEYYEGEWYADKRSGWGRMYYSDGAVYEGEWYDDK 143
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO33639 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRL1]) HSP 1 Score: 49.6766 bits (117), Expect = 1.262e-6 Identity = 25/57 (43.86%), Postives = 36/57 (63.16%), Query Frame = 2 Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSD-GSFEEGQYQNGKL 1438 Y G WV DQRHG+G ++ I+EG W+ NKRHG G +++ GS EG + G++ Sbjct: 89 YEGYWVNDQRHGYGTYTYANKDIFEGEWVQNKRHGQGTYTYAETGSRFEGTWFQGRM 145
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO30644 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T074]) HSP 1 Score: 49.6766 bits (117), Expect = 6.440e-6 Identity = 25/66 (37.88%), Postives = 36/66 (54.55%), Query Frame = 2 Query: 1238 GDTIAPDVFETYSGEWVQDQRHGFGVC--ERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQN 1429 GD ++ YSGEW +RHG GV +R Y+G WLNN RHG+ + G+ EG +++ Sbjct: 148 GDYSCSNLPAVYSGEWRHGKRHGRGVLKYDREGHSYYDGHWLNNMRHGYARRVYKGGNVYEGDWKD 213
BLAST of Junctophilin vs. Ensembl Nematostella
Match: EDO29067 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4P6]) HSP 1 Score: 45.0542 bits (105), Expect = 7.541e-6 Identity = 23/55 (41.82%), Postives = 32/55 (58.18%), Query Frame = 2 Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGK 1435 Y G + + +RHG GV DG IY+G W R G G K+++G EG ++NGK Sbjct: 15 YEGHYSKGKRHGQGVMYYPDGSIYDGTWSEGLRSGKGKYKYANGDVYEGNWKNGK 69
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph1a (junctophilin 1 [Source:NCBI gene;Acc:101173340]) HSP 1 Score: 214.157 bits (544), Expect = 5.036e-58 Identity = 151/452 (33.41%), Postives = 224/452 (49.56%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFL-PEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLS-GKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQ----SIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 + GR++F D G Y G W + KA G G+ T K QGE+ G W+ G E GV+ WPS G Y+G W+ KR G G+ K WI G++ GF GV+ + ++EG + +G +G+ETY DGGTY G + G+R G GVR S+PYG P + + N T L S+ D P + GFVL+ S+++ K +KGL R SL L K + + + ++ S +A+ SS +TI +A D+ D + ETY GEW D+R+GFGV ERS+G+ YEG WLNNKRHG+G T F D + EEG+Y+N L+ K+ + L + + + ++V+ A+ A+ A+ K + R + A++AA A S R + +E+ P++ QPG Sbjct: 1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYAGSWSHGFEIVGVYTWPS--GNTYKGYWSQGKRHGLGVENKGKWIYRGEWSHGFKGRYGVRQSHNTPARYEGTWSNGLQDGYGIETYGDGGTYQGQWMGGMRHGYGVRQSVPYGMATVIRSPLRTSMASLRSEQSNGTVLQDLSSPAD-------TPTGSRGGFVLNFHSDSEVVTGK----------KKGLFRRGSLFGSLRQLRKSDSRTSISSKRS--------SARSDATMSRISSSDANSTISIGDGELADDDLHLEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWLNNKRHGYGCTVFPDATKEEGKYKNNVLVRGIRKQ--LIPLKNPKTKEKVDRAVEGAQRAAAIARSKVEIAASRTAHARTKSEAAEQAAISAVHDSEIARAVARELSPNFYQPG 423
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:101163737]) HSP 1 Score: 213.386 bits (542), Expect = 2.290e-57 Identity = 152/448 (33.93%), Postives = 221/448 (49.33%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFL-PEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 GR+ F D G Y G W KA G G+ T K QGE+ G W G E GV+ WPS G Y+G WA KR G GI K W+ G++ GF G++ + GK+EG + +G +G ETY+DGGT+ G + G+R G GVR S+PYG P + + E+S + S + GS+ P + GFVL+ L+K K + GL R SI S L ++ + ++ S S G ++ S S + N+ S+ D A D + ETY GEW D+R GFGV RSDG+ YEG WL+NKRHG+G T F DG+ EEG+Y+ + I + KR + L + ++ + ++V+ A+ A+ A++K + + + A AA A+E S R K+ P ++ PG Sbjct: 4 GGRFNFDDGGSYCGGWEEGKAHGYGICTGPKGQGEYCGSWAHGFELLGVYTWPS--GNTYQGTWAQGKRHGVGIENKGRWVYKGEWTHGFKGRYGLRESTGTSGKYEGTWNNGLQDGYGTETYSDGGTFQGQWVGGMRHGYGVRQSVPYGMAAVIRSPLRTSINSLRSGSEHSNGTALVS--MCSTGSSGSSPAVSRGGFVLTAHSEAELLKG--------KRKSGLFR----RSILSGLKLRKSESRSSLASQRSKQSSFRSEAGMSTVSSAASDV--NSTISLGDADAELAVADDDVDATTTETYCGEWKNDKRTGFGVSRRSDGLQYEGEWLSNKRHGYGCTTFPDGTKEEGKYK--QNILVSGKRKNLIPLRASKIREKVDRAVEGAQKAADIARQKAEIALSRTAHAQGKAEAAVAAAQKAQEESRMARVTAKQFSPSFQHPG 431
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph3 (junctophilin 3 [Source:NCBI gene;Acc:101163737]) HSP 1 Score: 208.764 bits (530), Expect = 1.340e-55 Identity = 156/467 (33.40%), Postives = 224/467 (47.97%), Query Frame = 2 Query: 371 AGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGE---IFAFLPEEKHLLLKSATDENSTNLS-----------------FTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMS---AGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 GR+ F D G Y G W KA G G+ T K QGE+ G W G E GV+ WPS G Y+G WA KR G GI K W+ G++ GF G++ + GK+EG + +G +G ETY+DGGT+ G + G+R G GVR S+PYG I + L + L + N T L TS + GS+ P + GFVL+ L+K K + GL R SI S L ++ + ++ S S G ++ S S + N+ S+ D A D + ETY GEW D+R GFGV RSDG+ YEG WL+NKRHG+G T F DG+ EEG+Y+ + I + KR + L + ++ + ++V+ A+ A+ A++K + + + A AA A+E S R K+ P ++ PG Sbjct: 4 GGRFNFDDGGSYCGGWEEGKAHGYGICTGPKGQGEYCGSWAHGFELLGVYTWPS--GNTYQGTWAQGKRHGVGIENKGRWVYKGEWTHGFKGRYGLRESTGTSGKYEGTWNNGLQDGYGTETYSDGGTFQGQWVGGMRHGYGVRQSVPYGMAAVIRSPLRTSINSLRSGSEHSNGTALLDRTGAIVPGPPTVPGTLTTSVSMCSTGSSGSSPAVSRGGFVLTAHSEAELLKG--------KRKSGLFR----RSILSGLKLRKSESRSSLASQRSKQSSFRSEAGMSTVSSAASDV--NSTISLGDADAELAVADDDVDATTTETYCGEWKNDKRTGFGVSRRSDGLQYEGEWLSNKRHGYGCTTFPDGTKEEGKYK--QNILVSGKRKNLIPLRASKIREKVDRAVEGAQKAADIARQKAEIALSRTAHAQGKAEAAVAAAQKAQEESRMARVTAKQFSPSFQHPG 452
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph2 (junctophilin 2 [Source:NCBI gene;Acc:101175160]) HSP 1 Score: 206.068 bits (523), Expect = 6.886e-55 Identity = 145/459 (31.59%), Postives = 215/459 (46.84%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSN-----HVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIV 1720 + GR+EF D G Y G W KA G G+ T K QGE++G WN G E GV+ WPS G YEG W+ KR G G+ K WI G++ GF G + S K+EG + +G +G ETYADGGT+ G + G+R G GVR S+PYG + A + L S E+S + + +G + + G G L + A K +KGL R SL +++ + S S + + + + ++ ++ I E Y GEW D+R G+G+ ERS G+ YEG WLNN+RHG+G T F++G EEG+Y N L+ KR + L ++ ++++V+ A+ A+ A++K + T + A++AA A S R + KE+ P + QPG L V Sbjct: 1 MSGGRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEYSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVESKGHWIYKGEWTHGFKGRYGTRVSVGSGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYG-MAAVVRSPLRTSLTSLRSEHSNGTVLQQDIPVITTTNTSGEETPVATPTHLGPSRGGFALTLQVDP----EAVKPKKKGLFRRSSLLGKLKKSDSSVSLSSQKSKTSFLRPDSALSSNASDTNSTISGDESLLGVEDFPPVE----SDIDATTTEVYMGEWKNDKRSGYGISERSSGLKYEGEWLNNQRHGYGCTTFAEGGKEEGKYMNNMLVKAMKKR--MIQLKGNKIKQKVERAVEGAQRAAAIAKQKAEIAASRTTHAKAKSDGAEQAAHAANGESSIARLVAKELSPSFYQPGPEYLKKKV 446
BLAST of Junctophilin vs. Ensembl Medaka
Match: jph2 (junctophilin 2 [Source:NCBI gene;Acc:101175160]) HSP 1 Score: 204.912 bits (520), Expect = 1.535e-54 Identity = 146/455 (32.09%), Postives = 214/455 (47.03%), Query Frame = 2 Query: 365 LPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFEDGCP-VFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDL-LIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIV 1720 + GR+EF D G Y G W KA G G+ T K QGE++G WN G E GV+ WPS G YEG W+ KR G G+ K WI G++ GF G + S K+EG + +G +G ETYADGGT+ G + G+R G GVR S+PYG +A + S TS L ++ G VL + D+ +I A K +KGL R SL +++ + S S + + + + ++ ++ I E Y GEW D+R G+G+ ERS G+ YEG WLNN+RHG+G T F++G EEG+Y N L+ KR + L ++ ++++V+ A+ A+ A++K + T + A++AA A S R + KE+ P + QPG L V Sbjct: 1 MSGGRFEFDDGGAYCGGWEGGKAHGHGICTGPKGQGEYSGSWNYGFEVVGVYTWPS--GNTYEGYWSQGKRHGLGVESKGHWIYKGEWTHGFKGRYGTRVSVGSGAKYEGTWNNGLQDGYGTETYADGGTFQGQFTGGMRHGYGVRQSVPYG--------------MAAVVRSPLRTSLTS-----------LRSEHSNGTVL---QQDIPVITTTNTSEAVKPKKKGLFRRSSLLGKLKKSDSSVSLSSQKSKTSFLRPDSALSSNASDTNSTISGDESLLGVEDFPPVE----SDIDATTTEVYMGEWKNDKRSGYGISERSSGLKYEGEWLNNQRHGYGCTTFAEGGKEEGKYMNNMLVKAMKKR--MIQLKGNKIKQKVERAVEGAQRAAAIAKQKAEIAASRTTHAKAKSDGAEQAAHAANGESSIARLVAKELSPSFYQPGPEYLKKKV 419
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000065993.1 (SMESG000065993.1) HSP 1 Score: 1768.82 bits (4580), Expect = 0.000e+0 Identity = 897/899 (99.78%), Postives = 898/899 (99.89%), Query Frame = 2 Query: 332 MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNFLLVDADGEHRASRHGSFRRSKKLSTQNISKEIHQKQANKPTIEINHSSMPIKRIESQNCPEDPKLPHKLNQLESIQPITFHPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDAVPFXXXXXXXXXXXXXXXVYVPVGNIMATSRIPSETLSSIISSNTHIDYFNHYSQSNADQSEKILKSKIYXXXXXXXXXXXXXPRRFTVPEIMTQEPVHPTPVTSILRDLQEEVEDENSEFSDTMILMDGGIRKRVSPVPVNHIKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVSATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIKDYKIS 3028 MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVKKAKEAAALAREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNFLLVDADGEHRASRHGSFRRSKKLSTQNISKEIHQKQANKPTIEINHSSMPIKRIESQNCPEDPKLPHKLNQLESIQPITFHPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDA PFECETPIKEIEEIEEEVYVPVGNIMATSRIPSETLSSIISSNTHIDYFNHYSQSNADQSEKILKSKIYSMNSSSPNSNINNPRRFTVPEIMTQEPVHPTPVTSILRDLQEEVEDENSEFSDTMILMDGGIRKRVSPVPVN+IKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVSATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIKDYKIS Sbjct: 1 MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFITLGVKTKEKSIGKFEGEFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDCRKKLTEIRETVKKAKEAAALAREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNFLLVDADGEHRASRHGSFRRSKKLSTQNISKEIHQKQANKPTIEINHSSMPIKRIESQNCPEDPKLPHKLNQLESIQPITFHPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDAAPFECETPIKEIEEIEEEVYVPVGNIMATSRIPSETLSSIISSNTHIDYFNHYSQSNADQSEKILKSKIYSMNSSSPNSNINNPRRFTVPEIMTQEPVHPTPVTSILRDLQEEVEDENSEFSDTMILMDGGIRKRVSPVPVNNIKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVSATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIKDYKIS 899
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000001306.1 (SMESG000001306.1) HSP 1 Score: 285.804 bits (730), Expect = 1.967e-81 Identity = 260/965 (26.94%), Postives = 438/965 (45.39%), Query Frame = 2 Query: 359 SQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEGEFE----DGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNG--SASKLPNKFKCGFVLSGKKSDLLIKKLRHINACKKHQKGLKRSKSLTSIFSALTKKELYNTKNIHKNHFGTISVYSVPGNASPKSFHSSLTFNTIQSIAT-------MDMSAGDTIAPDVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMDC--RKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPGIRILTDIVRMMRVTKRGQKSFESMLQAAIDVVEGRGVPEMISTNDNLTVNYNKDNF------LLVDADGE----HRASRHGSFRRSKKLSTQ---NISKEIHQKQ--ANKPTIEINHSS-----MPIKRIESQNCP--EDPKLPHKLNQLESIQPITF---HPIQQSSKFDTIKLQETPILRVHESPVDFPKAQIVIDKVSDAVPFXXXXXXXXXXXXXXXVYVPVGNIMATSRIPSETLSS----------IISSNTHIDYFNHYSQSNADQSEKILKSKIYXXXXX------XXXXXXXXPRRFTVPEIMTQEPVHPTPVTSI-----LRDLQEEVEDENSEFSDTMILMDGGIRKR-------------VSPVPVNHIKSRTESKITLNQPQDGLRPLPMIFNFTSQLNLSKDLQEGSLPDVS-----ATKRMCGIPREEVIRLGEEYQHAIELDKQKLKQGVFVIRFYKLGDWLRDHAVSLVVIFINLCLLYFFIAIIK 3013 S + GR++F D G Y+GEW + +A G+G+ T ++QGEF+G W G E GV++WPS G +Y G W KR G G+ +K WI G+F GF GVK S KFEG + DG FG+ET ADG TY G + G+R+GLGVR S Y + +++AT +NS ++N D+ ++ P + GFVL ++ INA K+ + +++ +F L K++ +T ++ G S S+L+ N+ S AT + + + ++I P+V ETYSG+W +D+R G+GV ER+DG YEG W NNK+ G+G+T F +G+ EEG+Y+ L+ KR+ IF L R+ ++++VK A A+ A+E+ M+ ++ T +TV+ + G RI TD +++ + + + + E L ++ ++ L NY LL +D E SR GSFR S + S + N +QKQ ++KP N +S P+ + +C E PK+ H ++++ P T P+ Q + T+ Q+ P ++H + ++ + + A+ V G+++ E++SS + +T D+F++YS + ++ ++ Y + RR +VP IMT +PV +S+ D+ E NS + ++ +++ GIRKR +SP I R ++ + + D L PLP + S N + L EGSLPDVS TK + R+E +L ++ + I ++++ ++G VIR + DW + + ++++ +N + F+ I+K Sbjct: 2 SVIEGGRFDFDDGGSYVGEWCDGRAHGLGIATGPENQGEFSGEWVMGFESRGVYIWPS--GNIYAGGWMKGKRHGEGVQMKGKWIYKGEFTTGFCGRYGVKESLSSASKFEGSWHLNLFDG---FGVETNADGSTYSGAWSKGVRQGLGVRKSAAYSKAATHKDPSS---VRAATSQNSL---LSANDSDRQAFVDDARRPIDHRSGFVLVTTNNNA------DINANKEKKPSFRKA-----LFRKLRKQK--STGDLRSARMGG-------------SLRSTLSSNSAASQATNHSLPDSLPIPSRESIDPNVIETYSGQWKEDKRAGYGVAERTDGAKYEGEWYNNKKDGYGVTHFPNGTKEEGRYKENVLVQTLHKRHKIFALRHSRLKDSVEEAVKNAVEAAADAKERAMETANQRAQTAKNKTVQSCT-------------------------RSGKRICTDFIQLGVLWLKTRNNIEGKLTGSVVFNNNFS---LLDNQKYLNQNYKPQQMDQLQPNLLNPSDPECLEVSGGSRRGSFRSSFRRSGEKRPNSPDPQNQKQTSSSKPLSGHNPNSNMTPQKPVASPTNVDCYSFEVPKIGHSVSEVAQQTPTTLLTSEPLIQRATA-TLTRQKAP-QKIHSNIINIQPQNPKKEGLHYAI-------------------VQSGDVIKPQIAQIESISSYSEIEPRNVLVKEFDTGNDFFDYYSNNQSELNDGNFIDYEYEERRKIENEVLESKATRLEERRRSVPSIMTSKPVTANLTSSVKYPDNKYDIVHSSEILNS--TTSVYIIENGIRKRMKADENILPRQPPLSPKSNRLIGKRIQNPLNIEPEADELTPLPRNYKIESSHNPHRKL-EGSLPDVSYCNEIKTKTGTLMSRQEASQLSQQRRQEILHEQERQRRGEIVIRMADIKDWFKQNFTIVLILLLNCVIAVGFLHILK 877
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000004402.1 (SMESG000004402.1) HSP 1 Score: 199.519 bits (506), Expect = 7.425e-52 Identity = 148/495 (29.90%), Postives = 236/495 (47.68%), Query Frame = 2 Query: 356 YSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTGLWNSGSEKCGVFLWPSAPGAMYEGEWANSKRDGYGIFIKEDWIVMGKFQEGFI-TLGVKTKEKSIGKFEG-----EFEDGCPVFGMETYADGGTYCGDYKSGLREGLGVRTSIPYGEIFAFLPEEKHLLLKSATDENSTNLSFTSNHVDKNGSASKLPNKFKCGFVLSGKKS---------DLLIKKL-RHINACKKHQKGLKRSKSLTS----------------IFSALTKKELYNTKNIHKNHFGTI-----SVYSVPGNASPKSFHSSLTFNTIQSIATMDMSAGDTIAP----------DVFETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLIFLWTKRNPIFFLHSFRMGLHIKKSVKQARNASKKAQEKDMD-CRKKLTEIRETVXXXXXXXXXXREYSLETRQLVKEMYPDYEQPG 1696 +S G+++FKD G YIGEW + +A G G+ T +QGE++G W+ G E CGV++WPS G +YEG W KR G G+ + W+ G F GF GVK+ + ++EG EF DG +G+ET ADG TY G + R+GLGV S +G F S + + +SN + K+ A+++ N F F + KS ++L K +H ++ K Q +S S I + + L + + N + S+ S S+L ++ S+ ++ ++ P + ETY+G+W ++ R G GV ERSDG+ Y G WLNNKRHG+GIT F D + EEG+Y++ LI +++ IF + R+ + V++A + ++ A+ K ++ ++ A+ A AR S R + K++ P++EQPG Sbjct: 7 FSSKSGGKFDFKDGGTYIGEWCDGRAHGFGIATGPNNQGEYSGDWSVGFENCGVYIWPS--GNVYEGLWMKGKRHGEGVQVMGRWVYKGSFTTGFFGRYGVKSSLYTQSRYEGCWHLNEF-DG---YGIETCADGSTYAGMWFKNQRKGLGVSHSAQFGLANDFRDSRDSRPSMSDMSMHFGDCRESSNSIYKDCLANEIRNGFVLCFHSNKYKSKHHELSEIGNVLKKSFHKHQSSHKSDQTSTPTDQSSKSFKLHKKLLLHLRRKKPILDQRSARSLSRQRTVENNENEFLRNPSGSLKSTNSRDHSNQVASTLPTSSGSSLGKAGSNSFSSVVPGYDILSSIPKETVETYAGQWNENTRTGLGVAERSDGLKYIGEWLNNKRHGYGITCFPDNTIEEGRYKDNVLIQQLNRKSRIFLVKHSRLKNLVDDFVQKALDVAQDAKIKAVETAYQRAQTALAAAISAQARADDARTLSKSARNIAKQIAPNFEQPG 495
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000053274.1 (SMESG000053274.1) HSP 1 Score: 48.1358 bits (113), Expect = 4.260e-6 Identity = 25/57 (43.86%), Postives = 31/57 (54.39%), Query Frame = 2 Query: 1271 YSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNGKLI 1441 Y G++V D G G + G YEG +LNN HG G F DGSF EG + +LI Sbjct: 45 YDGDFVNDLMQGNGTLKFPSGAKYEGDFLNNMFHGEGKYTFPDGSFYEGNFDKNRLI 101
BLAST of Junctophilin vs. Planmine SMEST
Match: SMESG000011788.1 (SMESG000011788.1) HSP 1 Score: 49.2914 bits (116), Expect = 6.120e-6 Identity = 23/56 (41.07%), Postives = 37/56 (66.07%), Query Frame = 2 Query: 1265 ETYSGEWVQDQRHGFGVCERSDGVIYEGGWLNNKRHGFGITKFSDGSFEEGQYQNG 1432 E Y GEW + +R+G+G +DG +YEG W N++ G G+ + +G+ EGQ++NG Sbjct: 116 EFYEGEWYEGKRNGWGRMYEADGNVYEGEWENDQMCGQGMLRNKNGNRYEGQWKNG 171 The following BLAST results are available for this feature:
BLAST of Junctophilin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Junctophilin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Junctophilin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Junctophilin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Junctophilin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Junctophilin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Junctophilin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Junctophilin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Junctophilin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Junctophilin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Junctophilin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Junctophilin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Junctophilin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Junctophilin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031366 ID=SMED30031366|Name=Junctophilin|organism=Schmidtea mediterranea sexual|type=transcript|length=3422bpback to top protein sequence of SMED30031366-orf-1 >SMED30031366-orf-1 ID=SMED30031366-orf-1|Name=SMED30031366-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=900bp MDGVPEEVYSQLPAGRYEFKDSGIYIGEWLNEKAVGIGLLTKDKSQGEFTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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