slc26a-4

Overview


Name	slc26a-4 (AKN21608.1)
Smed ID	SMED30031335
Length (bp)	623

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30031335

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30031335	SMESG000064566.1	Contig33181	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30031335	SMESG000064566.1	Contig33181	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Category 3 cell	SMED30031335	SMESG000064562.1	dd_Smed_v6_4250_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of slc26a-4 vs. Ensembl Human
Match: SLC26A3 (solute carrier family 26 member 3 [Source:HGNC Symbol;Acc:HGNC:3018])

HSP 1 Score: 107.071 bits (266), Expect = 2.520e-26
Identity = 64/183 (34.97%), Postives = 103/183 (56.28%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID-FPLNTTKTVG-----NVSASVQNEAIKASRVAGLTLFVGISQ 623
            RPVY+ + F+E+H  K T +  K   ++  K   S   + +  K+  LS FP    L  Y+ K WLL D+++G+  G + + Q  A+A LV I P+YGLY +FFP ++Y FFG+SRHIS+G   I+S++ G  +  ++    P     T+G     N S+ + +E ++ +  A +T+  GI Q
Sbjct:   13 RPVYSTNAFEENH--KKTGRHHK-TFLDHLKVCCS--CSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQ 190

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BLAST of slc26a-4 vs. Ensembl Human
Match: SLC26A4 (solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818])

HSP 1 Score: 98.9821 bits (245), Expect = 1.880e-23
Identity = 62/184 (33.70%), Postives = 95/184 (51.63%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSK--FPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNV--SASVQNEAIKASRV---AGLTLFVGISQ 623
            RPVY++  F + H  +  E+        T ++  +K  +    + F + K   P +  L +Y+ K WLL D+I+G+  G +   Q  AYA L  +   YGLY AFFP++ Y+ FG+SRHIS+G   +VSL+ GS +     D     + + G V  +  +   A   +RV   + LTL VGI Q
Sbjct:   24 RPVYSELAFQQQHERRLQER-------KTLRESLAKCCSCSRKRAFGVLKTLVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGTSRHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVLIASALTLLVGIIQ 200

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BLAST of slc26a-4 vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359])

HSP 1 Score: 92.0485 bits (227), Expect = 3.236e-22
Identity = 63/183 (34.43%), Postives = 100/183 (54.64%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPI---LMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            RP+++     E     +T+  + + I +   K+K  +  +   KK     + F+PI   L  YK+K ++L DL++G+  G +Q+PQ  A+A L  + PI+GLY +F+PV++Y F G+SRHISIG  A++SL+ G    + + D         G V+A+   EA  A RV     +TL  GI Q
Sbjct:   20 RPIFSHPVLQER---LHTKDKVPDSIAD---KLKQAFTCTP--KKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPD----DIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQ 190

[Close]

BLAST of slc26a-4 vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359])

HSP 1 Score: 92.0485 bits (227), Expect = 1.090e-21
Identity = 63/183 (34.43%), Postives = 100/183 (54.64%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPI---LMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            RP+++     E     +T+  + + I +   K+K  +  +   KK     + F+PI   L  YK+K ++L DL++G+  G +Q+PQ  A+A L  + PI+GLY +F+PV++Y F G+SRHISIG  A++SL+ G    + + D         G V+A+   EA  A RV     +TL  GI Q
Sbjct:   20 RPIFSHPVLQER---LHTKDKVPDSIAD---KLKQAFTCTP--KKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPD----DIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQ 190

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BLAST of slc26a-4 vs. Ensembl Human
Match: SLC26A5 (solute carrier family 26 member 5 [Source:HGNC Symbol;Acc:HGNC:9359])

HSP 1 Score: 92.8189 bits (229), Expect = 2.502e-21
Identity = 65/178 (36.52%), Postives = 95/178 (53.37%), Query Frame = 3

Query:  141 YTEKPI-KEQIINTFKKVKSKYFNSEGGK-KFALSKFP---------FVPI---LMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            Y E+PI    ++      K K  +S   K K A +  P         F+PI   L  YK+K ++L DL++G+  G +Q+PQ  A+A L  + PI+GLY +F+PV++Y F G+SRHISIG  A++SL+ G    + + D         G V+A+   EA  A RV     +TL  GI Q
Sbjct:   17 YVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPD----DIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQ 190

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BLAST of slc26a-4 vs. Ensembl Celegans
Match: sulp-4 (Anion transporter SULP-4; SULfate Permease family [Source:UniProtKB/TrEMBL;Acc:G5EEA7])

HSP 1 Score: 97.0561 bits (240), Expect = 3.025e-23
Identity = 53/138 (38.41%), Postives = 76/138 (55.07%), Query Frame = 3

Query:   93 RPVYTQHEFDE--DHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQ 500
            R    Q +FDE  D+   + E  +K+Q     ++    + +    K F     P +     YKWKT L LD+I G+ VG MQ+PQ  AYA L     I GLY + FP ++Y  FG+SRH S+GT A+VSL++G  +E+
Sbjct:   43 RGAMNQAQFDEKFDYNKPHLENELKKQAKKFVRRFYEPFTSFFALKLFIFDLIPILKWFPEYKWKTDLSLDIIGGITVGVMQVPQGIAYALLAKQPAINGLYTSLFPPLIYMLFGTSRHASLGTFAVVSLMTGLSVEK 180

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BLAST of slc26a-4 vs. Ensembl Celegans
Match: sulp-7 (Anion transporter SULP-7a; SULfate Permease family [Source:UniProtKB/TrEMBL;Acc:G5EGG6])

HSP 1 Score: 91.2781 bits (225), Expect = 3.750e-22
Identity = 52/129 (40.31%), Postives = 74/129 (57.36%), Query Frame = 3

Query:  246 PFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSF---LEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            P    L  Y     L+ D+I G+ VG + +PQ  AYA LVG++P+YGLY + FP ++Y FFG+SRH+++G  A+VSL+SGS    + Q +I          G    S + EAI  + V  L L VG+ Q
Sbjct:   14 PITKWLPNYSISENLINDIIGGVTVGILNVPQGMAYASLVGLKPVYGLYTSLFPSLIYMFFGTSRHVALGVFAVVSLMSGSCNLRVTQEIIS-------NNGTNMTSTEVEAISINVVKSLGLAVGLIQ 135

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BLAST of slc26a-4 vs. Ensembl Celegans
Match: sulp-8 (Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family [Source:UniProtKB/TrEMBL;Acc:G5EFB2])

HSP 1 Score: 93.2041 bits (230), Expect = 7.072e-22
Identity = 48/128 (37.50%), Postives = 72/128 (56.25%), Query Frame = 3

Query:  249 FVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            ++PIL     Y+WK     D+IAGL VG M +PQ  AYA L G+ P+YG+Y +FF   +Y FFG++RHISIG  A+ S++ G+   +   D P++ +  +      +          + LTL VG+ Q
Sbjct:   31 YIPILEWLPNYQWKDHFHGDVIAGLTVGIMHVPQGMAYASLAGVPPVYGMYSSFFASTIYMFFGTARHISIGVFAVASMMVGAARLRLAPDIPISNSSDINPSVYPLGEYVDPLVFTSALTLLVGVVQ 158

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Query:  249 FVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            ++PIL     Y+WK     D+IAGL VG M +PQ  AYA L G+ P+YG+Y +FF   +Y FFG++RHISIG  A+ S++ G+   +   D P++ +  +      +          + LTL VG+ Q
Sbjct:   31 YIPILEWLPNYQWKDHFHGDVIAGLTVGIMHVPQGMAYASLAGVPPVYGMYSSFFASTIYMFFGTARHISIGVFAVASMMVGAARLRLAPDIPISNSSDINPSVYPLGEYVDPLVFTSALTLLVGVVQ 158

[Close]

Query:  249 FVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            ++PIL     Y+WK     D+IAGL VG M +PQ  AYA L G+ P+YG+Y +FF   +Y FFG++RHISIG  A+ S++ G+   +   D P++ +  +      +          + LTL VG+ Q
Sbjct:   31 YIPILEWLPNYQWKDHFHGDVIAGLTVGIMHVPQGMAYASLAGVPPVYGMYSSFFASTIYMFFGTARHISIGVFAVASMMVGAARLRLAPDIPISNSSDINPSVYPLGEYVDPLVFTSALTLLVGVVQ 158

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BLAST of slc26a-4 vs. Ensembl Fly
Match: CG5002 (gene:FBgn0034275 transcript:FBtr0089546)

HSP 1 Score: 72.7886 bits (177), Expect = 8.331e-15
Identity = 40/112 (35.71%), Postives = 63/112 (56.25%), Query Frame = 3

Query:  159 KEQIINTFKKVKSKYFNSEGGKKFA-----LSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLL 479
            +EQ+ N    ++      +GG+K        +KFP +  L RY+ + +++ D IAG  VG   IPQ+ AY  + G++P YGLY AF     Y  FGS + ++I T AI++L+
Sbjct:   10 REQLPNVSTLIR------DGGRKLCRPSTVTNKFPILKWLPRYRLE-YIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTYIVFGSCKDVTIATTAIMALM 114

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BLAST of slc26a-4 vs. Ensembl Fly
Match: Prestin (gene:FBgn0036770 transcript:FBtr0075153)

HSP 1 Score: 71.633 bits (174), Expect = 2.036e-14
Identity = 35/84 (41.67%), Postives = 50/84 (59.52%), Query Frame = 3

Query:  246 PFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLE 497
            P +  L +Y  +  L  D+IAG  V  M IP   AY  L G+    GLY+A FPV+ Y F G+S+HISIGT A+ S+++   ++
Sbjct:   82 PILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVD 165

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BLAST of slc26a-4 vs. Ensembl Fly
Match: CG9702 (gene:FBgn0039787 transcript:FBtr0336449)

HSP 1 Score: 68.1662 bits (165), Expect = 3.185e-13
Identity = 39/107 (36.45%), Postives = 58/107 (54.21%), Query Frame = 3

Query:  183 KKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQS 503
            +   S+Y  +   KK  L + PF+  L  Y  +  +  DLIAG  VG   IPQ  AY+ +VG+ P YGLY +F    VY   G+ +  +IG+ A+ SL++  F + S
Sbjct:   58 ESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIG-DLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFAQGS 163

[Close]

BLAST of slc26a-4 vs. Ensembl Fly
Match: CG9702 (gene:FBgn0039787 transcript:FBtr0336448)

HSP 1 Score: 68.1662 bits (165), Expect = 3.220e-13
Identity = 39/107 (36.45%), Postives = 58/107 (54.21%), Query Frame = 3

Query:  183 KKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQS 503
            +   S+Y  +   KK  L + PF+  L  Y  +  +  DLIAG  VG   IPQ  AY+ +VG+ P YGLY +F    VY   G+ +  +IG+ A+ SL++  F + S
Sbjct:   58 ESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIG-DLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFAQGS 163

[Close]

BLAST of slc26a-4 vs. Ensembl Fly
Match: CG9702 (gene:FBgn0039787 transcript:FBtr0085664)

HSP 1 Score: 68.1662 bits (165), Expect = 3.220e-13
Identity = 39/107 (36.45%), Postives = 58/107 (54.21%), Query Frame = 3

Query:  183 KKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQS 503
            +   S+Y  +   KK  L + PF+  L  Y  +  +  DLIAG  VG   IPQ  AY+ +VG+ P YGLY +F    VY   G+ +  +IG+ A+ SL++  F + S
Sbjct:   58 ESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIG-DLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFAQGS 163

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BLAST of slc26a-4 vs. Ensembl Zebrafish
Match: slc26a5 (solute carrier family 26 member 5 [Source:ZFIN;Acc:ZDB-GENE-030131-1566])

HSP 1 Score: 107.071 bits (266), Expect = 1.922e-26
Identity = 72/191 (37.70%), Postives = 102/191 (53.40%), Query Frame = 3

Query:   93 RPVYTQHEFDED--HGGKYTEKPIK----EQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID--FPLNTTKTVGNVSASVQNEAIKASR---VAGLTLFVGISQ 623
            RP++++   D +  H  K T KP K    E +  + +KVKS  F              F+PIL     Y  K +L  D+++G+  G MQ+PQ  AYA L  + P++GLY +F+PV++Y FFG+S+HISIGT A++SL+ G    +   D  F +N T    N S  V  EA  + R   V  LT  VGI Q
Sbjct:   20 RPIFSEAYIDSELLHKRKKTPKPYKLRVAEHLCCSSEKVKSVVFG-------------FLPILTWLPSYPLKEYLFGDIVSGISTGVMQLPQGLAYAMLAAVPPVFGLYSSFYPVLLYTFFGTSKHISIGTFAVISLMIGGVAVREAPDSMFMVNGT----NSSLVVNIEARDSRRVEVVVALTTLVGIIQ 193

[Close]

BLAST of slc26a-4 vs. Ensembl Zebrafish
Match: slc26a5 (solute carrier family 26 member 5 [Source:ZFIN;Acc:ZDB-GENE-030131-1566])

HSP 1 Score: 106.686 bits (265), Expect = 2.203e-26
Identity = 72/191 (37.70%), Postives = 102/191 (53.40%), Query Frame = 3

Query:   93 RPVYTQHEFDED--HGGKYTEKPIK----EQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID--FPLNTTKTVGNVSASVQNEAIKASR---VAGLTLFVGISQ 623
            RP++++   D +  H  K T KP K    E +  + +KVKS  F              F+PIL     Y  K +L  D+++G+  G MQ+PQ  AYA L  + P++GLY +F+PV++Y FFG+S+HISIGT A++SL+ G    +   D  F +N T    N S  V  EA  + R   V  LT  VGI Q
Sbjct:   20 RPIFSEAYIDSELLHKRKKTPKPYKLRVAEHLCCSSEKVKSVVFG-------------FLPILTWLPSYPLKEYLFGDIVSGISTGVMQLPQGLAYAMLAAVPPVFGLYSSFYPVLLYTFFGTSKHISIGTFAVISLMIGGVAVREAPDSMFMVNGT----NSSLVVNIEARDSRRVEVVVALTTLVGIIQ 193

[Close]

BLAST of slc26a-4 vs. Ensembl Zebrafish
Match: slc26a10 (solute carrier family 26 member 10 [Source:ZFIN;Acc:ZDB-GENE-030131-9845])

HSP 1 Score: 103.605 bits (257), Expect = 2.503e-25
Identity = 55/145 (37.93%), Postives = 88/145 (60.69%), Query Frame = 3

Query:   90 FRPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSK-FPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPL 521
            +R +YT+  F + +G +  +   +E++ +   ++  +   S+      L K  P    L +YK + WLL D+IAGL VG + IPQ  A+A L  + P+YGLY +FFPV++Y  FG+  H+S GT A++SL++GS +EQ L+  PL
Sbjct:    8 YRNIYTEDRFRQTYGTE-DQSGGRERLRD---RLAQRCSCSQVECVHLLHKRLPVCSWLPKYKLRKWLLGDIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTGHHVSTGTFAVLSLMTGSVVEQ-LVPIPL 147

[Close]

BLAST of slc26a-4 vs. Ensembl Zebrafish
Match: slc26a10 (solute carrier family 26 member 10 [Source:ZFIN;Acc:ZDB-GENE-030131-9845])

HSP 1 Score: 102.834 bits (255), Expect = 5.460e-25
Identity = 46/94 (48.94%), Postives = 65/94 (69.15%), Query Frame = 3

Query:  240 KFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPL 521
            + P    L +YK + WLL D+IAGL VG + IPQ  A+A L  + P+YGLY +FFPV++Y  FG+  H+S GT A++SL++GS +EQ L+  PL
Sbjct:   55 RLPVCSWLPKYKLRKWLLGDIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTGHHVSTGTFAVLSLMTGSVVEQ-LVPIPL 147

[Close]

Query:  240 KFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPL 521
            + P    L +YK + WLL D+IAGL VG + IPQ  A+A L  + P+YGLY +FFPV++Y  FG+  H+S GT A++SL++GS +EQ L+  PL
Sbjct:   55 RLPVCSWLPKYKLRKWLLGDIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTGHHVSTGTFAVLSLMTGSVVEQ-LVPIPL 147

[Close]

BLAST of slc26a-4 vs. Ensembl Xenopus
Match: SLC26A5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:100497573])

HSP 1 Score: 115.546 bits (288), Expect = 2.776e-29
Identity = 75/191 (39.27%), Postives = 102/191 (53.40%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKP------IKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID-----FPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RPV+TQ E+ E+      ++P      IK+    T KK KS+ ++             F+PIL    RY  K +LL D+I+GL  G MQ+PQ  AYA L G+ P+YGLY +F+PV +Y FFGSSRHISIGT A++SL+ G    +   D      P N T +          +A++   V  LTL  GI Q
Sbjct:   21 RPVFTQ-EYVEEQLHLRKDEPKSLVHKIKQSCRCTSKKAKSQLYS-------------FIPILKWLPRYPVKEYLLGDVISGLSTGVMQLPQGLAYALLAGVPPVYGLYSSFYPVFLYTFFGSSRHISIGTFAVISLMIGGVAVRIAPDEMFDIMPANGTNSTDFDEKIEARDAMRVKVVVALTLLSGIIQ 197

[Close]

BLAST of slc26a-4 vs. Ensembl Xenopus
Match: SLC26A5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:100497573])

HSP 1 Score: 115.546 bits (288), Expect = 3.142e-29
Identity = 75/191 (39.27%), Postives = 102/191 (53.40%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKP------IKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID-----FPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RPV+TQ E+ E+      ++P      IK+    T KK KS+ ++             F+PIL    RY  K +LL D+I+GL  G MQ+PQ  AYA L G+ P+YGLY +F+PV +Y FFGSSRHISIGT A++SL+ G    +   D      P N T +          +A++   V  LTL  GI Q
Sbjct:   21 RPVFTQ-EYVEEQLHLRKDEPKSLVHKIKQSCRCTSKKAKSQLYS-------------FIPILKWLPRYPVKEYLLGDVISGLSTGVMQLPQGLAYALLAGVPPVYGLYSSFYPVFLYTFFGSSRHISIGTFAVISLMIGGVAVRIAPDEMFDIMPANGTNSTDFDEKIEARDAMRVKVVVALTLLSGIIQ 197

[Close]

BLAST of slc26a-4 vs. Ensembl Xenopus
Match: SLC26A5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:100497573])

HSP 1 Score: 115.161 bits (287), Expect = 4.236e-29
Identity = 75/191 (39.27%), Postives = 102/191 (53.40%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKP------IKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID-----FPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RPV+TQ E+ E+      ++P      IK+    T KK KS+ ++             F+PIL    RY  K +LL D+I+GL  G MQ+PQ  AYA L G+ P+YGLY +F+PV +Y FFGSSRHISIGT A++SL+ G    +   D      P N T +          +A++   V  LTL  GI Q
Sbjct:   21 RPVFTQ-EYVEEQLHLRKDEPKSLVHKIKQSCRCTSKKAKSQLYS-------------FIPILKWLPRYPVKEYLLGDVISGLSTGVMQLPQGLAYALLAGVPPVYGLYSSFYPVFLYTFFGSSRHISIGTFAVISLMIGGVAVRIAPDEMFDIMPANGTNSTDFDEKIEARDAMRVKVVVALTLLSGIIQ 197

[Close]

BLAST of slc26a-4 vs. Ensembl Xenopus
Match: kcnk6 (potassium channel, two pore domain subfamily K, member 6 [Source:Xenbase;Acc:XB-GENE-958681])

HSP 1 Score: 111.309 bits (277), Expect = 7.236e-28
Identity = 69/154 (44.81%), Postives = 92/154 (59.74%), Query Frame = 3

Query:  180 FKKVKSKYFNSEGGKKFALSKFPFVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASR---VAGLTLFVGISQ 623
            F   K K   S    K  L  F F+PIL    RY  K WLL D+++G+ VG +Q+PQ  AYA L G+ P++GLY +FFPVMVY  FG+SRH+SIG+ A+VS++ GS  E SL+  P +     GN S  +   A   +R   VA +TL VG+ Q
Sbjct:   40 FGAAKRKLRCSVSAAKHIL--FQFIPILHWLPRYPVKEWLLGDIVSGVSVGILQLPQGLAYALLAGVPPVFGLYSSFFPVMVYSIFGTSRHVSIGSFAVVSIMIGSVTE-SLV--PNDNFILPGNDSLHIDTVARDKARVEVVAAMTLLVGLFQ 188

[Close]

BLAST of slc26a-4 vs. Ensembl Xenopus
Match: kcnk6 (potassium channel, two pore domain subfamily K, member 6 [Source:Xenbase;Acc:XB-GENE-958681])

HSP 1 Score: 110.153 bits (274), Expect = 2.296e-27
Identity = 63/133 (47.37%), Postives = 86/133 (64.66%), Query Frame = 3

Query:  243 FPFVPILM---RYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASR---VAGLTLFVGISQ 623
            F F+PIL    RY  K WLL D+++G+ VG +Q+PQ  AYA L G+ P++GLY +FFPVMVY  FG+SRH+SIG+ A+VS++ GS  E SL+  P +     GN S  +   A   +R   VA +TL VG+ Q
Sbjct:   18 FQFIPILHWLPRYPVKEWLLGDIVSGVSVGILQLPQGLAYALLAGVPPVFGLYSSFFPVMVYSIFGTSRHVSIGSFAVVSIMIGSVTE-SLV--PNDNFILPGNDSLHIDTVARDKARVEVVAAMTLLVGLFQ 147

[Close]

BLAST of slc26a-4 vs. Ensembl Mouse
Match: Slc26a3 (solute carrier family 26, member 3 [Source:MGI Symbol;Acc:MGI:107181])

HSP 1 Score: 98.2117 bits (243), Expect = 6.740e-25
Identity = 52/129 (40.31%), Postives = 75/129 (58.14%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLL 479
            RPVY+   F E+    +      +  ++  K   S   +S+  KK ALS FP    L  YK K WLL D+++G+  G + + Q  A+A LV I P YGLY AFFPV+ Y+F G+SRHIS+G   ++S++
Sbjct:   13 RPVYSTKTFGEEFKKTHRHH---KTFLDHLKGCCS--CSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMM 136

[Close]

BLAST of slc26a-4 vs. Ensembl Mouse
Match: Slc26a3 (solute carrier family 26, member 3 [Source:MGI Symbol;Acc:MGI:107181])

HSP 1 Score: 98.5969 bits (244), Expect = 1.900e-23
Identity = 55/129 (42.64%), Postives = 77/129 (59.69%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLL 479
            RPVY+   F E+   K T +  K   ++  K   S   +S+  KK ALS FP    L  YK K WLL D+++G+  G + + Q  A+A LV I P YGLY AFFPV+ Y+F G+SRHIS+G   ++S++
Sbjct:   13 RPVYSTKTFGEEF--KKTHRHHK-TFLDHLKGCCS--CSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMM 136

[Close]

BLAST of slc26a-4 vs. Ensembl Mouse
Match: Slc26a5 (solute carrier family 26, member 5 [Source:MGI Symbol;Acc:MGI:1933154])

HSP 1 Score: 97.8265 bits (242), Expect = 2.594e-23
Identity = 68/189 (35.98%), Postives = 101/189 (53.44%), Query Frame = 3

Query:  108 QHEFDEDHGGKYTEKPI-KEQIINTFKKVKSKYFNSEGGK-KFALSKFP---------FVPI---LMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            ++E   +    Y E+PI    ++     VK K   S G K K A +  P         F+PI   L  YK+K ++L DL++G+  G +Q+PQ  A+A L  + P++GLY +F+PV++Y FFG+SRHISIG  A++SL+ G    + + D         G V+A+   EA  A RV     +TL  GI Q
Sbjct:    6 ENEIPAETQRYYVERPIFSHPVLQERLHVKDKVTESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPD----DIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQ 190

[Close]

BLAST of slc26a-4 vs. Ensembl Mouse
Match: Slc26a5 (solute carrier family 26, member 5 [Source:MGI Symbol;Acc:MGI:1933154])

HSP 1 Score: 97.0561 bits (240), Expect = 2.842e-23
Identity = 68/189 (35.98%), Postives = 101/189 (53.44%), Query Frame = 3

Query:  108 QHEFDEDHGGKYTEKPI-KEQIINTFKKVKSKYFNSEGGK-KFALSKFP---------FVPI---LMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            ++E   +    Y E+PI    ++     VK K   S G K K A +  P         F+PI   L  YK+K ++L DL++G+  G +Q+PQ  A+A L  + P++GLY +F+PV++Y FFG+SRHISIG  A++SL+ G    + + D         G V+A+   EA  A RV     +TL  GI Q
Sbjct:    6 ENEIPAETQRYYVERPIFSHPVLQERLHVKDKVTESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPD----DIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQ 190

[Close]

BLAST of slc26a-4 vs. Ensembl Mouse
Match: Slc26a5 (solute carrier family 26, member 5 [Source:MGI Symbol;Acc:MGI:1933154])

HSP 1 Score: 97.8265 bits (242), Expect = 2.971e-23
Identity = 68/189 (35.98%), Postives = 101/189 (53.44%), Query Frame = 3

Query:  108 QHEFDEDHGGKYTEKPI-KEQIINTFKKVKSKYFNSEGGK-KFALSKFP---------FVPI---LMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            ++E   +    Y E+PI    ++     VK K   S G K K A +  P         F+PI   L  YK+K ++L DL++G+  G +Q+PQ  A+A L  + P++GLY +F+PV++Y FFG+SRHISIG  A++SL+ G    + + D         G V+A+   EA  A RV     +TL  GI Q
Sbjct:    6 ENEIPAETQRYYVERPIFSHPVLQERLHVKDKVTESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPD----DIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQ 190

[Close]

BLAST of slc26a-4 vs. UniProt/SwissProt
Match: sp|P40879|S26A3_HUMAN (Chloride anion exchanger OS=Homo sapiens OX=9606 GN=SLC26A3 PE=1 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 1.210e-25
Identity = 64/183 (34.97%), Postives = 103/183 (56.28%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID-FPLNTTKTVG-----NVSASVQNEAIKASRVAGLTLFVGISQ 623
            RPVY+ + F+E+H  K T +  K   ++  K   S   + +  K+  LS FP    L  Y+ K WLL D+++G+  G + + Q  A+A LV I P+YGLY +FFP ++Y FFG+SRHIS+G   I+S++ G  +  ++    P     T+G     N S+ + +E ++ +  A +T+  GI Q
Sbjct:   13 RPVYSTNAFEENH--KKTGRHHK-TFLDHLKVCCS--CSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQ 190

[Close]

BLAST of slc26a-4 vs. UniProt/SwissProt
Match: sp|Q924C9|S26A3_RAT (Chloride anion exchanger OS=Rattus norvegicus OX=10116 GN=Slc26a3 PE=2 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 3.491e-24
Identity = 64/180 (35.56%), Postives = 100/180 (55.56%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            RPVY+   F E+    Y      +  ++  K   S   +S+  KK ALS FP    L  YK K WLL D+++G+  G + + Q  A+A LV I P YGLY AFFPV+ Y+F G+SRHIS+G   ++S++ G  + +  +    +T+  +   S+S +N+++   +V   A +T+  GI Q
Sbjct:   13 RPVYSTKAFGEEFKKTYGHH---KTFLDHLKGCCS--CSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTR--VASGSDTSPALS--SSSAENDSMIEEKVMVAASVTVLSGIIQ 183

[Close]

BLAST of slc26a-4 vs. UniProt/SwissProt
Match: sp|O43511|S26A4_HUMAN (Pendrin OS=Homo sapiens OX=9606 GN=SLC26A4 PE=1 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 9.029e-23
Identity = 62/184 (33.70%), Postives = 95/184 (51.63%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSK--FPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNV--SASVQNEAIKASRV---AGLTLFVGISQ 623
            RPVY++  F + H  +  E+        T ++  +K  +    + F + K   P +  L +Y+ K WLL D+I+G+  G +   Q  AYA L  +   YGLY AFFP++ Y+ FG+SRHIS+G   +VSL+ GS +     D     + + G V  +  +   A   +RV   + LTL VGI Q
Sbjct:   24 RPVYSELAFQQQHERRLQER-------KTLRESLAKCCSCSRKRAFGVLKTLVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGTSRHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVLIASALTLLVGIIQ 200

[Close]

BLAST of slc26a-4 vs. UniProt/SwissProt
Match: sp|Q9WVC8|S26A3_MOUSE (Chloride anion exchanger OS=Mus musculus OX=10090 GN=Slc26a3 PE=1 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 1.329e-22
Identity = 55/129 (42.64%), Postives = 77/129 (59.69%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLL 479
            RPVY+   F E+   K T +  K   ++  K   S   +S+  KK ALS FP    L  YK K WLL D+++G+  G + + Q  A+A LV I P YGLY AFFPV+ Y+F G+SRHIS+G   ++S++
Sbjct:   13 RPVYSTKTFGEEF--KKTHRHHK-TFLDHLKGCCS--CSSQKAKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMM 136

[Close]

BLAST of slc26a-4 vs. UniProt/SwissProt
Match: sp|Q99NH7|S26A5_MOUSE (Prestin OS=Mus musculus OX=10090 GN=Slc26a5 PE=2 SV=3)

HSP 1 Score: 97.8265 bits (242), Expect = 2.078e-22
Identity = 68/189 (35.98%), Postives = 101/189 (53.44%), Query Frame = 3

Query:  108 QHEFDEDHGGKYTEKPI-KEQIINTFKKVKSKYFNSEGGK-KFALSKFP---------FVPI---LMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            ++E   +    Y E+PI    ++     VK K   S G K K A +  P         F+PI   L  YK+K ++L DL++G+  G +Q+PQ  A+A L  + P++GLY +F+PV++Y FFG+SRHISIG  A++SL+ G    + + D         G V+A+   EA  A RV     +TL  GI Q
Sbjct:    6 ENEIPAETQRYYVERPIFSHPVLQERLHVKDKVTESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPD----DIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQ 190

[Close]

BLAST of slc26a-4 vs. TrEMBL
Match: A0A0H3YKD1 (Slc26a-4 OS=Schmidtea mediterranea OX=79327 GN=slc26a-4 PE=2 SV=1)

HSP 1 Score: 241.506 bits (615), Expect = 4.662e-74
Identity = 120/120 (100.00%), Postives = 120/120 (100.00%), Query Frame = 3

Query:  264 MRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            MRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ
Sbjct:    1 MRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 120

[Close]

BLAST of slc26a-4 vs. TrEMBL
Match: A0A0H3YFH1 (Slc26a-8 OS=Schmidtea mediterranea OX=79327 GN=slc26a-8 PE=2 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 4.868e-59
Identity = 100/196 (51.02%), Postives = 132/196 (67.35%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPL----NTTKTVGNVSASVQN---------------EAIKASRVAGLTLFVGISQ 623
            RP+YTQHEFD +HGG Y +K  K + ++  +  K +Y N +G K+    K PF+ I+M+YKW+ WLL D IAGLIVG M IPQS AYA L G++PIYGLY +FFPV+VY+FFG+SRHISIGTIAI+SLL+G FLE+SL+DFP+    N+   + N + S  +               E +KA+RVAG    VG+ Q
Sbjct:   33 RPIYTQHEFDLNHGGNYIKKSWKRKFMSKVRSTKKEYVNKQGMKRCIREKLPFISIMMKYKWREWLLADFIAGLIVGIMHIPQSMAYAHLAGLKPIYGLYGSFFPVIVYFFFGTSRHISIGTIAIISLLTGKFLEKSLLDFPIKIANNSLTFLANENISFLSSNDSLRLSQETSKITELLKANRVAGFAFLVGVVQ 228

[Close]

BLAST of slc26a-4 vs. TrEMBL
Match: A0A1I8I6N8 (STAS domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 4.613e-34
Identity = 75/185 (40.54%), Postives = 106/185 (57.30%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKV--------KSKYFNSEGGKKFALSK------FPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTL 605
            RPVYTQ +FDE HGG+   +P+  ++ ++ KK+        +S   + E G   + +K       PF+ IL RY  + WLL D I+GL VG M IPQ  AYA L  + P  GLY +FFP ++Y+FFG+SR +S+GT+AI+SLL G  + +   +FP     T+G+   S  NE   A     LTL
Sbjct:   89 RPVYTQQQFDEKHGGRLVRRPLLARLRDSAKKLMTCGAGSGRSDDGDGESGHNCSRAKTQLLGFLPFIGILKRYNIRDWLLADFISGLTVGIMHIPQGMAYAFLAELPPYIGLYTSFFPPLIYFFFGTSRQVSMGTVAIISLLVGGLVSK---NFP----ATLGSAVGSFDNETTTAIASQQLTL 266

[Close]

BLAST of slc26a-4 vs. TrEMBL
Match: A0A267FXS2 (STAS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005698g2 PE=3 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 4.934e-34
Identity = 75/186 (40.32%), Postives = 106/186 (56.99%), Query Frame = 3

Query:   90 FRPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKV--------KSKYFNSEGGKKFALSK------FPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTL 605
             RPVYTQ +FDE HGG+   +P+  ++ ++ KK+        +S   + E G   + +K       PF+ IL RY  + WLL D I+GL VG M IPQ  AYA L  + P  GLY +FFP ++Y+FFG+SR +S+GT+AI+SLL G  + +   +FP     T+G+   S  NE   A     LTL
Sbjct:  107 IRPVYTQQQFDEKHGGRLVRRPLLARLRDSAKKLMTCGAGSGRSDDGDGESGHNCSRAKTQLLGFLPFIGILKRYNIRDWLLADFISGLTVGIMHIPQGMAYAFLAELPPYIGLYTSFFPPLIYFFFGTSRQVSMGTVAIISLLVGGLVSK---NFP----ATLGSAVGSFDNETTTAIASQQLTL 285

[Close]

BLAST of slc26a-4 vs. TrEMBL
Match: A0A267ECE9 (STAS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005698g1 PE=3 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 5.030e-34
Identity = 75/185 (40.54%), Postives = 106/185 (57.30%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKV--------KSKYFNSEGGKKFALSK------FPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTL 605
            RPVYTQ +FDE HGG+   +P+  ++ ++ KK+        +S   + E G   + +K       PF+ IL RY  + WLL D I+GL VG M IPQ  AYA L  + P  GLY +FFP ++Y+FFG+SR +S+GT+AI+SLL G  + +   +FP     T+G+   S  NE   A     LTL
Sbjct:  108 RPVYTQQQFDEKHGGRLVRRPLLARLRDSAKKLVTCGAGSGRSDDGDGESGHNCSRAKAQLLGFLPFIGILKRYNIRDWLLADFISGLTVGIMHIPQGMAYAFLAELPPYIGLYTSFFPPLIYFFFGTSRQVSMGTVAIISLLVGGLVSK---NFP----ATLGSAVGSFDNETTTAIASQQLTL 285

[Close]

BLAST of slc26a-4 vs. Ensembl Cavefish
Match: slc26a5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:103036170])

HSP 1 Score: 108.997 bits (271), Expect = 3.346e-27
Identity = 69/181 (38.12%), Postives = 97/181 (53.59%), Query Frame = 3

Query:  117 FDEDH-------GGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID--FPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            FDE+H         + T K I +++  + +       +SE  K    S  P +  L  Y  K +L  D+++GL  G MQ+PQ  AYA L  + P+YGLY +F+PV++Y  FG+SRHIS+GT A++SL+ G    +   D  FPLN T    NV+  V  EA  A RV     LT  VG+ Q
Sbjct:   29 FDEEHLSSQLLHKKERTPKSIGQRLAESCR------CSSERAKSAIFSFLPILSWLPSYPVKEYLFGDIVSGLSTGVMQLPQGLAYAMLAAVPPVYGLYSSFYPVLLYTLFGTSRHISMGTFAVISLMIGGVAVREAPDSMFPLNGT----NVTGLVDFEARDARRVQVAVALTTLVGLIQ 199

[Close]

BLAST of slc26a-4 vs. Ensembl Cavefish
Match: slc26a3.2 (solute carrier family 26 member 3, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-041210-179])

HSP 1 Score: 101.679 bits (252), Expect = 1.010e-24
Identity = 64/179 (35.75%), Postives = 100/179 (55.87%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYF--NSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RP+YT+  F E+H      + ++ +   T   VK +YF  +S+  K  ALS  P V  +  Y+ K WLL D+++G+  G + I Q  AY+ L  +   YGLY AFFPV++Y+F G+SRHIS+G   ++SL+ G+ + + + D    T    G    S+ ++  +A   A LT  +GI Q
Sbjct:   13 RPLYTEDSFTENH------EKVERKHKTTLDHVK-QYFTCDSKRVKNAALSLVPIVGWMKMYRVKEWLLGDIVSGVSTGLVAILQGLAYSLLASLPAWYGLYAAFFPVIIYFFLGTSRHISVGAFPVLSLMVGAVVTRMVPDGG-PTVNITGLEGLSIDDQ--RAMVSASLTFLIGIFQ 181

[Close]

BLAST of slc26a-4 vs. Ensembl Cavefish
Match: slc26a3.2 (solute carrier family 26 member 3, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-041210-179])

HSP 1 Score: 101.679 bits (252), Expect = 1.067e-24
Identity = 64/179 (35.75%), Postives = 100/179 (55.87%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYF--NSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RP+YT+  F E+H      + ++ +   T   VK +YF  +S+  K  ALS  P V  +  Y+ K WLL D+++G+  G + I Q  AY+ L  +   YGLY AFFPV++Y+F G+SRHIS+G   ++SL+ G+ + + + D    T    G    S+ ++  +A   A LT  +GI Q
Sbjct:   11 RPLYTEDSFTENH------EKVERKHKTTLDHVK-QYFTCDSKRVKNAALSLVPIVGWMKMYRVKEWLLGDIVSGVSTGLVAILQGLAYSLLASLPAWYGLYAAFFPVIIYFFLGTSRHISVGAFPVLSLMVGAVVTRMVPDGG-PTVNITGLEGLSIDDQ--RAMVSASLTFLIGIFQ 179

[Close]

BLAST of slc26a-4 vs. Ensembl Cavefish
Match: slc26a3.2 (solute carrier family 26 member 3, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-041210-179])

HSP 1 Score: 101.679 bits (252), Expect = 1.070e-24
Identity = 64/179 (35.75%), Postives = 100/179 (55.87%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYF--NSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RP+YT+  F E+H      + ++ +   T   VK +YF  +S+  K  ALS  P V  +  Y+ K WLL D+++G+  G + I Q  AY+ L  +   YGLY AFFPV++Y+F G+SRHIS+G   ++SL+ G+ + + + D    T    G    S+ ++  +A   A LT  +GI Q
Sbjct:   35 RPLYTEDSFTENH------EKVERKHKTTLDHVK-QYFTCDSKRVKNAALSLVPIVGWMKMYRVKEWLLGDIVSGVSTGLVAILQGLAYSLLASLPAWYGLYAAFFPVIIYFFLGTSRHISVGAFPVLSLMVGAVVTRMVPDGG-PTVNITGLEGLSIDDQ--RAMVSASLTFLIGIFQ 203

[Close]

BLAST of slc26a-4 vs. Ensembl Cavefish
Match: slc26a3.2 (solute carrier family 26 member 3, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-041210-179])

HSP 1 Score: 101.679 bits (252), Expect = 1.073e-24
Identity = 64/179 (35.75%), Postives = 100/179 (55.87%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYF--NSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RP+YT+  F E+H      + ++ +   T   VK +YF  +S+  K  ALS  P V  +  Y+ K WLL D+++G+  G + I Q  AY+ L  +   YGLY AFFPV++Y+F G+SRHIS+G   ++SL+ G+ + + + D    T    G    S+ ++  +A   A LT  +GI Q
Sbjct:   12 RPLYTEDSFTENH------EKVERKHKTTLDHVK-QYFTCDSKRVKNAALSLVPIVGWMKMYRVKEWLLGDIVSGVSTGLVAILQGLAYSLLASLPAWYGLYAAFFPVIIYFFLGTSRHISVGAFPVLSLMVGAVVTRMVPDGG-PTVNITGLEGLSIDDQ--RAMVSASLTFLIGIFQ 180

[Close]

BLAST of slc26a-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003427.1 (pep scaffold:Pmarinus_7.0:GL476526:256569:262630:-1 gene:ENSPMAG00000003117.1 transcript:ENSPMAT00000003427.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.4337 bits (228), Expect = 3.681e-22
Identity = 40/95 (42.11%), Postives = 63/95 (66.32%), Query Frame = 3

Query:  222 KKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSL 506
            K F L+ FP +  L +YK + W+L D ++GLIVG + +PQ  AY+ L G  PIYGLY +FF  ++Y+  G+S+HIS+G   ++ L+ G  +++ L
Sbjct:   49 KSFFLNLFPVLRWLPKYKVREWILGDFMSGLIVGILLVPQCIAYSLLAGQDPIYGLYTSFFACIIYFLMGTSKHISVGIFGVLCLMIGQVVDREL 143

[Close]

BLAST of slc26a-4 vs. Ensembl Sea Lamprey
Match: slc26a11 (solute carrier family 26 member 11 [Source:ZFIN;Acc:ZDB-GENE-030131-5349])

HSP 1 Score: 63.929 bits (154), Expect = 1.832e-12
Identity = 31/72 (43.06%), Postives = 46/72 (63.89%), Query Frame = 3

Query:  288 LLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQS 503
            L +DL+AGL VG   +PQS AYAQ+ G+   YGLY AF    VY   G+S+ +++G  AI+SL+   ++ + 
Sbjct:    6 LRMDLVAGLTVGLTVVPQSLAYAQVAGLPAQYGLYSAFMGCFVYCLLGTSKDVTLGPTAIMSLVVSVYVRRD 77

[Close]

BLAST of slc26a-4 vs. Ensembl Yeast
Match: SUL1 (High affinity sulfate permease of the SulP anion transporter family; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates [Source:SGD;Acc:S000000498])

HSP 1 Score: 77.0258 bits (188), Expect = 5.450e-17
Identity = 36/118 (30.51%), Postives = 65/118 (55.08%), Query Frame = 3

Query:  204 FNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSAS 557
              ++    + +S FP +     Y + TW   DL+AG+ VG + +PQS +YAQ+  + P YGLY +F    +Y  F +S+ + IG +A++SL +   + + L  +P + T+    + A+
Sbjct:   94 LTAKSAGSYLVSLFPIIKWFPHYNF-TWGYADLVAGITVGCVLVPQSMSYAQIASLSPEYGLYSSFIGAFIYSLFATSKDVCIGPVAVMSLQTAKVIAEVLKKYPEDQTEVTAPIIAT 210

[Close]

BLAST of slc26a-4 vs. Ensembl Yeast
Match: SUL2 (High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates [Source:SGD;Acc:S000004082])

HSP 1 Score: 72.0182 bits (175), Expect = 2.270e-15
Identity = 37/115 (32.17%), Postives = 61/115 (53.04%), Query Frame = 3

Query:  213 EGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSAS 557
            +G   +  S FP +  L  Y + +W   DLIAG+ +G + +PQS +YAQ+  +   YGLY +F     Y FF +S+ + IG +A++SL +   +      +P   +   G V A+
Sbjct:  113 KGACSYLKSVFPIINWLPHYNF-SWFTADLIAGITIGCVLVPQSMSYAQVATLPAQYGLYSSFIGAYSYSFFATSKDVCIGPVAVMSLQTAKVIADVTAKYPDGDSAITGPVIAT 226

[Close]

BLAST of slc26a-4 vs. Ensembl Nematostella
Match: EDO34158 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ57])

HSP 1 Score: 72.4034 bits (176), Expect = 4.688e-17
Identity = 40/89 (44.94%), Postives = 53/89 (59.55%), Query Frame = 3

Query:  207 NSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVS 473
            + E  KK+   +FP    L +Y    +L  DLIAGL VG M +PQ  AYA + G+ P YGLY AF    VY  FG+S+ I++G  AI+S
Sbjct:    4 DLEAIKKYTKKRFPIAKWLSKYNLH-FLQCDLIAGLTVGLMVVPQGLAYALVAGLPPQYGLYSAFMGCFVYCVFGTSKDITLGPTAIMS 91

[Close]

BLAST of slc26a-4 vs. Ensembl Nematostella
Match: EDO48275 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJJ6])

HSP 1 Score: 76.6406 bits (187), Expect = 1.460e-16
Identity = 42/111 (37.84%), Postives = 63/111 (56.76%), Query Frame = 3

Query:  159 KEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSF 491
            +E++     +   +  + E  KK+   +FP    L +Y    +L  DLIAGL VG M +PQ  AYA + G+ P YGLY AF    VY  FG+S+ I++G  AI+SL+  ++
Sbjct:   11 QEELEEKCAESCQRKIDLEAIKKYTKKRFPIAKWLSKYNLH-FLQCDLIAGLTVGLMVVPQGLAYALVAGLPPQYGLYSAFMGCFVYCVFGTSKDITLGPTAIMSLIVSAY 120

[Close]

BLAST of slc26a-4 vs. Ensembl Nematostella
Match: EDO49691 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG03])

HSP 1 Score: 75.8702 bits (185), Expect = 2.891e-16
Identity = 43/147 (29.25%), Postives = 72/147 (48.98%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSK---------FPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSL 506
            R   T+ +F  D  GK+ +K          + ++ +   S  GK   ++          FP V  L +Y ++   + DL  G+ VG M IPQ  A+A L  + P+ GLY A  PVM+Y   G+S+++S G+ A++ L+     E+ +
Sbjct:   21 RSALTEGQFG-DFYGKHEKKTFDN------RSLRKRVLTSVTGKVTGMTCSPLETLEKLFPIVQWLPKYNFRKEFVADLTGGMTVGVMHIPQGLAFAMLASLPPVTGLYTALIPVMIYMLMGTSKYLSQGSFAVICLMVAQVSEREV 160

[Close]

BLAST of slc26a-4 vs. Ensembl Nematostella
Match: EDO48274 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJJ5])

HSP 1 Score: 65.4698 bits (158), Expect = 1.443e-13
Identity = 32/72 (44.44%), Postives = 44/72 (61.11%), Query Frame = 3

Query:  288 LLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQS 503
            L  D+I GL VG M IPQ  AYA + G+  +YGLY AF    +Y  FG+S+ +S+G  AI+SL+   +   S
Sbjct:   15 LQCDMIGGLTVGLMVIPQGLAYATIAGLPTVYGLYSAFMGCFIYCIFGTSKDVSLGPTAIMSLIVNQYCHYS 86

[Close]

BLAST of slc26a-4 vs. Ensembl Medaka
Match: slc26a5 (solute carrier family 26 member 5 [Source:NCBI gene;Acc:101175455])

HSP 1 Score: 105.145 bits (261), Expect = 7.396e-26
Identity = 67/184 (36.41%), Postives = 99/184 (53.80%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYF--NSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLID--FPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGISQ 623
            RPVY       D     T+   + +   TF++  ++ F   S   K  AL+  PF+  L  Y  K +LL D+++GL    +Q+PQ  AYA L  + P+YGLY +F+PV++Y FFG+SRH+S+GT A++SL+ G    +   D  FP+ +     N S+    EA +  RV     LT  VGI Q
Sbjct:   22 RPVY-------DEAFLRTQLLHRRENTTTFRQRLAEKFQCTSSKAKAVALTFLPFLTWLPTYPVKKYLLSDVVSGLSTSVVQLPQGLAYAMLAAVPPVYGLYSSFYPVVLYAFFGTSRHVSVGTFAVISLMIGGVAVREAPDHMFPVFSGNATNN-SSVFDKEACENRRVQVAVVLTTLVGIIQ 197

[Close]

BLAST of slc26a-4 vs. Ensembl Medaka
Match: slc26a10 (solute carrier family 26 member 10 [Source:NCBI gene;Acc:101171246])

HSP 1 Score: 102.834 bits (255), Expect = 3.757e-25
Identity = 61/185 (32.97%), Postives = 98/185 (52.97%), Query Frame = 3

Query:   90 FRPVYTQHEF------DEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRV---AGLTLFVGI 617
            +R ++T+  F      +ED GG      +++++    +  +  + +          + P    L RYK + W+L D IAGL VG + IPQ  A+A L  + PI+GLY +FFPV++Y  FG+  H+S GT A+VSL++GS +EQ L+  PL         S+S +    +A R+   + + L  GI
Sbjct:    8 YRDIFTEDRFKQAYGSEEDTGGGVR---LRDRLAGRCRCSREAFLH------LLRERVPIFRWLPRYKLRKWILGDTIAGLTVGILHIPQGMAFALLTSVAPIFGLYTSFFPVVLYMIFGTGHHVSTGTFAVVSLMTGSVVEQ-LVPTPLEMN------SSSPEAAGFEAQRIGVASAVALLSGI 176

[Close]

BLAST of slc26a-4 vs. Ensembl Medaka
Match: slc26a6 (solute carrier family 26 member 6 [Source:NCBI gene;Acc:101169607])

HSP 1 Score: 102.064 bits (253), Expect = 7.159e-25
Identity = 60/179 (33.52%), Postives = 95/179 (53.07%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVS--ASVQNEAIKASRVAGLTLFVGISQ 623
            R +  + E DE      +  P  E++  + +    +       KK   S  P +  L RY +K + + DLI+G+ VG MQ+PQ  AYA L  + PI+GLY +F+PV++Y+ FG+S+HIS+GT A++S++ G   E+   D    T   V N +   +V  +A +    A +T   GI Q
Sbjct:   13 RQILDEGEVDELAHKDDSHFPFSERVKKSVRCSGPRL------KKALFSTIPILSWLPRYPFKEYAVGDLISGISVGIMQLPQGMAYALLASVPPIFGLYSSFYPVLIYFIFGTSKHISLGTYAVMSVMIGGVTERLAPDSDFMTWDNVTNATLIDTVARDAERVRVAAAVTFMSGIFQ 185

[Close]

BLAST of slc26a-4 vs. Ensembl Medaka
Match: slc26a6 (solute carrier family 26 member 6 [Source:NCBI gene;Acc:101169607])

HSP 1 Score: 102.064 bits (253), Expect = 8.936e-25
Identity = 60/179 (33.52%), Postives = 95/179 (53.07%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVS--ASVQNEAIKASRVAGLTLFVGISQ 623
            R +  + E DE      +  P  E++  + +    +       KK   S  P +  L RY +K + + DLI+G+ VG MQ+PQ  AYA L  + PI+GLY +F+PV++Y+ FG+S+HIS+GT A++S++ G   E+   D    T   V N +   +V  +A +    A +T   GI Q
Sbjct:   13 RQILDEGEVDELAHKDDSHFPFSERVKKSVRCSGPRL------KKALFSTIPILSWLPRYPFKEYAVGDLISGISVGIMQLPQGMAYALLASVPPIFGLYSSFYPVLIYFIFGTSKHISLGTYAVMSVMIGGVTERLAPDSDFMTWDNVTNATLIDTVARDAERVRVAAAVTFMSGIFQ 185

[Close]

BLAST of slc26a-4 vs. Ensembl Medaka
Match: slc26a3.2 (solute carrier family 26 member 3 [Source:NCBI gene;Acc:101169253])

HSP 1 Score: 98.9821 bits (245), Expect = 1.028e-23
Identity = 61/181 (33.70%), Postives = 100/181 (55.25%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGG--KKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDF--PLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            RP+Y++  F E+H   Y ++   + +++  K     YF  +    K  ALS  P +  L  Y+ K WLL D+++G+  G + + Q  AY  L  + P YGL+ AFFPV++Y+F G+SRHIS+G   ++ L+ GS + + + D   P+N T   G    SV ++ +  +  + +T  VGI Q
Sbjct:   13 RPLYSEDSFAEEHEKVYRQR---KTMLDHLKL----YFTCDVKRVKHAALSLLPVIGWLRIYRIKEWLLPDVVSGVSTGLVAVLQGMAYCLLASLPPWYGLFSAFFPVVIYFFMGTSRHISVGPFPVLCLMIGSVVTRLIPDEGPPVNITGLEG---LSVDDQRVLVA--SSVTFLVGIMQ 181

[Close]

BLAST of slc26a-4 vs. Planmine SMEST
Match: SMESG000064571.1 (SMESG000064571.1)

HSP 1 Score: 255.758 bits (652), Expect = 2.403e-82
Identity = 124/148 (83.78%), Postives = 136/148 (91.89%), Query Frame = 3

Query:  180 FKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            FK+ K KY+NSEG K+F L KFPF+PILMRYKWK WLLLDLIAGLIVGTMQIPQSFAYAQLVGI+PIYGLYLAFFPV+VYYFFGSS+HISIGT+AIVSLL+G+FLEQ+LIDFPL+      NVSASVQNEAIKASRVAGLTLFVGISQ
Sbjct:    2 FKRFKGKYWNSEGVKRFFLGKFPFIPILMRYKWKNWLLLDLIAGLIVGTMQIPQSFAYAQLVGIKPIYGLYLAFFPVLVYYFFGSSKHISIGTVAIVSLLTGNFLEQTLIDFPLSKHTNFSNVSASVQNEAIKASRVAGLTLFVGISQ 149

[Close]

BLAST of slc26a-4 vs. Planmine SMEST
Match: SMESG000064566.1 (SMESG000064566.1)

HSP 1 Score: 243.047 bits (619), Expect = 5.112e-77
Identity = 120/120 (100.00%), Postives = 120/120 (100.00%), Query Frame = 3

Query:  264 MRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 623
            MRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ
Sbjct:    1 MRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLTLFVGISQ 120

[Close]

BLAST of slc26a-4 vs. Planmine SMEST
Match: SMESG000064562.1 (SMESG000064562.1)

HSP 1 Score: 207.608 bits (527), Expect = 1.172e-62
Identity = 100/196 (51.02%), Postives = 132/196 (67.35%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPL----NTTKTVGNVSASVQN---------------EAIKASRVAGLTLFVGISQ 623
            RP+YTQHEFD +HGG Y +K  K + ++  +  K +Y N +G K+    K PF+ I+M+YKW+ WLL D IAGLIVG M IPQS AYA L G++PIYGLY +FFPV+VY+FFG+SRHISIGTIAI+SLL+G FLE+SL+DFP+    N+   + N + S  +               E +KA+RVAG    VG+ Q
Sbjct:   33 RPIYTQHEFDLNHGGNYIKKSWKRKFMSKVRSTKKEYVNKQGMKRCIREKLPFISIMMKYKWREWLLADFIAGLIVGIMHIPQSMAYAHLAGLKPIYGLYGSFFPVIVYFFFGTSRHISIGTIAIISLLTGKFLEKSLLDFPIKIANNSLSFLANENISFLSSNDSLRLSQETSKITELLKANRVAGFAFLVGVVQ 228

[Close]

BLAST of slc26a-4 vs. Planmine SMEST
Match: SMESG000064562.1 (SMESG000064562.1)

HSP 1 Score: 207.223 bits (526), Expect = 1.186e-62
Identity = 100/196 (51.02%), Postives = 132/196 (67.35%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPL----NTTKTVGNVSASVQN---------------EAIKASRVAGLTLFVGISQ 623
            RP+YTQHEFD +HGG Y +K  K + ++  +  K +Y N +G K+    K PF+ I+M+YKW+ WLL D IAGLIVG M IPQS AYA L G++PIYGLY +FFPV+VY+FFG+SRHISIGTIAI+SLL+G FLE+SL+DFP+    N+   + N + S  +               E +KA+RVAG    VG+ Q
Sbjct:   33 RPIYTQHEFDLNHGGNYIKKSWKRKFMSKVRSTKKEYVNKQGMKRCIREKLPFISIMMKYKWREWLLADFIAGLIVGIMHIPQSMAYAHLAGLKPIYGLYGSFFPVIVYFFFGTSRHISIGTIAIISLLTGKFLEKSLLDFPIKIANNSLSFLANENISFLSSNDSLRLSQETSKITELLKANRVAGFAFLVGVVQ 228

[Close]

BLAST of slc26a-4 vs. Planmine SMEST
Match: SMESG000064565.1 (SMESG000064565.1)

HSP 1 Score: 171.785 bits (434), Expect = 1.479e-49
Identity = 78/179 (43.58%), Postives = 118/179 (65.92%), Query Frame = 3

Query:   93 RPVYTQHEFDEDHGGKYTEKPIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDLIAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISIGTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQN--EAIKASRVAGLTLFVGISQ 623
            RP  +Q+EFD+++     +  IK Q+I + K  +  + +      F   KFPF+ IL +YKWK  LL DLI G+IVG M IPQ  AY+QL G++P++GLY++ FP ++Y+FFG+S+HISIG++AI SL++  FLE+SL+DFP+ T   +     +  N  E + ++R AG   FVG++Q
Sbjct:   61 RPTLSQYEFDQNYEINTDQLSIKSQLIESSKDFQRNFCSRNNFYNFLCGKFPFIFILYKYKWKECLLEDLITGIIVGIMHIPQGMAYSQLAGLRPVHGLYVSLFPALIYFFFGTSKHISIGSMAIASLMTNKFLEKSLVDFPIQTVHNITTDYDTANNEFERLVSNRAAGFAFFVGLTQ 239

The following BLAST results are available for this feature:

BLAST of slc26a-4 vs. Ensembl Human
BLAST of slc26a-4 vs. Ensembl Celegans
BLAST of slc26a-4 vs. Ensembl Fly
BLAST of slc26a-4 vs. Ensembl Zebrafish
BLAST of slc26a-4 vs. Ensembl Xenopus
BLAST of slc26a-4 vs. Ensembl Mouse
BLAST of slc26a-4 vs. UniProt/SwissProt
BLAST of slc26a-4 vs. TrEMBL
BLAST of slc26a-4 vs. Ensembl Cavefish
BLAST of slc26a-4 vs. Ensembl Sea Lamprey
BLAST of slc26a-4 vs. Ensembl Yeast
BLAST of slc26a-4 vs. Ensembl Nematostella
BLAST of slc26a-4 vs. Ensembl Medaka
BLAST of slc26a-4 vs. Planmine SMEST

BLAST of slc26a-4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC26A3	2.520e-26	34.97	solute carrier family 26 member 3 [Source:HGNC Sym...	[more]
SLC26A4	1.880e-23	33.70	solute carrier family 26 member 4 [Source:HGNC Sym...	[more]
SLC26A5	3.236e-22	34.43	solute carrier family 26 member 5 [Source:HGNC Sym...	[more]
SLC26A5	1.090e-21	34.43	solute carrier family 26 member 5 [Source:HGNC Sym...	[more]
SLC26A5	2.502e-21	36.52	solute carrier family 26 member 5 [Source:HGNC Sym...	[more]

BLAST of slc26a-4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sulp-4	3.025e-23	38.41	Anion transporter SULP-4; SULfate Permease family ...	[more]
sulp-7	3.750e-22	40.31	Anion transporter SULP-7a; SULfate Permease family...	[more]
sulp-8	7.072e-22	37.50	Anion transporter SULP-8a; Anion transporter SULP-...	[more]
sulp-8	7.072e-22	37.50	Anion transporter SULP-8a; Anion transporter SULP-...	[more]
sulp-8	7.072e-22	37.50	Anion transporter SULP-8a; Anion transporter SULP-...	[more]

BLAST of slc26a-4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG5002	8.331e-15	35.71	gene:FBgn0034275 transcript:FBtr0089546	[more]
Prestin	2.036e-14	41.67	gene:FBgn0036770 transcript:FBtr0075153	[more]
CG9702	3.185e-13	36.45	gene:FBgn0039787 transcript:FBtr0336449	[more]
CG9702	3.220e-13	36.45	gene:FBgn0039787 transcript:FBtr0336448	[more]
CG9702	3.220e-13	36.45	gene:FBgn0039787 transcript:FBtr0085664	[more]

BLAST of slc26a-4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc26a5	1.922e-26	37.70	solute carrier family 26 member 5 [Source:ZFIN;Acc...	[more]
slc26a5	2.203e-26	37.70	solute carrier family 26 member 5 [Source:ZFIN;Acc...	[more]
slc26a10	2.503e-25	37.93	solute carrier family 26 member 10 [Source:ZFIN;Ac...	[more]
slc26a10	5.460e-25	48.94	solute carrier family 26 member 10 [Source:ZFIN;Ac...	[more]
slc26a10	5.460e-25	48.94	solute carrier family 26 member 10 [Source:ZFIN;Ac...	[more]

BLAST of slc26a-4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC26A5	2.776e-29	39.27	solute carrier family 26 member 5 [Source:NCBI gen...	[more]
SLC26A5	3.142e-29	39.27	solute carrier family 26 member 5 [Source:NCBI gen...	[more]
SLC26A5	4.236e-29	39.27	solute carrier family 26 member 5 [Source:NCBI gen...	[more]
kcnk6	7.236e-28	44.81	potassium channel, two pore domain subfamily K, me...	[more]
kcnk6	2.296e-27	47.37	potassium channel, two pore domain subfamily K, me...	[more]

BLAST of slc26a-4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Slc26a3	6.740e-25	40.31	solute carrier family 26, member 3 [Source:MGI Sym...	[more]
Slc26a3	1.900e-23	42.64	solute carrier family 26, member 3 [Source:MGI Sym...	[more]
Slc26a5	2.594e-23	35.98	solute carrier family 26, member 5 [Source:MGI Sym...	[more]
Slc26a5	2.842e-23	35.98	solute carrier family 26, member 5 [Source:MGI Sym...	[more]
Slc26a5	2.971e-23	35.98	solute carrier family 26, member 5 [Source:MGI Sym...	[more]

BLAST of slc26a-4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P40879\|S26A3_HUMAN	1.210e-25	34.97	Chloride anion exchanger OS=Homo sapiens OX=9606 G...	[more]
sp\|Q924C9\|S26A3_RAT	3.491e-24	35.56	Chloride anion exchanger OS=Rattus norvegicus OX=1...	[more]
sp\|O43511\|S26A4_HUMAN	9.029e-23	33.70	Pendrin OS=Homo sapiens OX=9606 GN=SLC26A4 PE=1 SV...	[more]
sp\|Q9WVC8\|S26A3_MOUSE	1.329e-22	42.64	Chloride anion exchanger OS=Mus musculus OX=10090 ...	[more]
sp\|Q99NH7\|S26A5_MOUSE	2.078e-22	35.98	Prestin OS=Mus musculus OX=10090 GN=Slc26a5 PE=2 S...	[more]

BLAST of slc26a-4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YKD1	4.662e-74	100.00	Slc26a-4 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A0H3YFH1	4.868e-59	51.02	Slc26a-8 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A1I8I6N8	4.613e-34	40.54	STAS domain-containing protein OS=Macrostomum lign...	[more]
A0A267FXS2	4.934e-34	40.32	STAS domain-containing protein OS=Macrostomum lign...	[more]
A0A267ECE9	5.030e-34	40.54	STAS domain-containing protein OS=Macrostomum lign...	[more]

BLAST of slc26a-4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc26a5	3.346e-27	38.12	solute carrier family 26 member 5 [Source:NCBI gen...	[more]
slc26a3.2	1.010e-24	35.75	solute carrier family 26 member 3, tandem duplicat...	[more]
slc26a3.2	1.067e-24	35.75	solute carrier family 26 member 3, tandem duplicat...	[more]
slc26a3.2	1.070e-24	35.75	solute carrier family 26 member 3, tandem duplicat...	[more]
slc26a3.2	1.073e-24	35.75	solute carrier family 26 member 3, tandem duplicat...	[more]

BLAST of slc26a-4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000003427.1	3.681e-22	42.11	pep scaffold:Pmarinus_7.0:GL476526:256569:262630:-...	[more]
slc26a11	1.832e-12	43.06	solute carrier family 26 member 11 [Source:ZFIN;Ac...	[more]

BLAST of slc26a-4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
SUL1	5.450e-17	30.51	High affinity sulfate permease of the SulP anion t...	[more]
SUL2	2.270e-15	32.17	High affinity sulfate permease; sulfate uptake is ...	[more]

BLAST of slc26a-4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO34158	4.688e-17	44.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48275	1.460e-16	37.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49691	2.891e-16	29.25	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48274	1.443e-13	44.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of slc26a-4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc26a5	7.396e-26	36.41	solute carrier family 26 member 5 [Source:NCBI gen...	[more]
slc26a10	3.757e-25	32.97	solute carrier family 26 member 10 [Source:NCBI ge...	[more]
slc26a6	7.159e-25	33.52	solute carrier family 26 member 6 [Source:NCBI gen...	[more]
slc26a6	8.936e-25	33.52	solute carrier family 26 member 6 [Source:NCBI gen...	[more]
slc26a3.2	1.028e-23	33.70	solute carrier family 26 member 3 [Source:NCBI gen...	[more]

BLAST of slc26a-4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000064571.1	2.403e-82	83.78	SMESG000064571.1	[more]
SMESG000064566.1	5.112e-77	100.00	SMESG000064566.1	[more]
SMESG000064562.1	1.172e-62	51.02	SMESG000064562.1	[more]
SMESG000064562.1	1.186e-62	51.02	SMESG000064562.1	[more]
SMESG000064565.1	1.479e-49	43.58	SMESG000064565.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30031335
GenBank	AKN21608.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30031335 ID=SMED30031335|Name=slc26a-4|organism=Schmidtea mediterranea sexual|type=transcript|length=623bp
AAAGAAATATTGTACAAAATTCGACTGGTTCGCCAGAGACCAAGGAGATC
GAAAATTCTTCTAAAAGCAAAAATAATAACATTTACATATTTCGGCCAGT
TTATACGCAACATGAATTCGATGAGGATCACGGGGGTAAATATACAGAAA
AGCCGATCAAAGAACAAATTATAAATACATTCAAAAAAGTTAAAAGCAAG
TATTTTAATTCAGAAGGCGGAAAAAAGTTTGCTCTTAGTAAATTCCCATT
TGTTCCAATATTAATGCGATACAAATGGAAAACTTGGTTACTTTTAGATT
TAATTGCCGGTCTTATCGTAGGTACCATGCAGATTCCACAAAGTTTTGCC
TATGCCCAATTAGTTGGTATTCAACCAATTTATGGCTTATATCTAGCATT
TTTCCCAGTAATGGTGTATTACTTTTTCGGATCTTCGAGACACATTTCAA
TAGGAACTATAGCTATTGTTAGTTTATTATCGGGAAGTTTTTTGGAGCAA
TCTTTAATAGATTTTCCTCTAAATACAACTAAAACTGTTGGAAATGTGTC
AGCATCAGTTCAAAATGAGGCAATTAAAGCCAGTCGAGTAGCCGGGTTGA
CACTTTTTGTTGGAATTTCACAA

protein sequence of SMED30031335-orf-1

>SMED30031335-orf-1 ID=SMED30031335-orf-1|Name=SMED30031335-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=207bp
RNIVQNSTGSPETKEIENSSKSKNNNIYIFRPVYTQHEFDEDHGGKYTEK
PIKEQIINTFKKVKSKYFNSEGGKKFALSKFPFVPILMRYKWKTWLLLDL
IAGLIVGTMQIPQSFAYAQLVGIQPIYGLYLAFFPVMVYYFFGSSRHISI
GTIAIVSLLSGSFLEQSLIDFPLNTTKTVGNVSASVQNEAIKASRVAGLT
LFVGISQ

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000035	Category 3 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001902	SLC26A/SulP_fam
IPR011547	SLC26A/SulP_dom

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016323	basolateral plasma membrane

Vocabulary: **molecular function**
Term	Definition
GO:0015116	sulfate transmembrane transporter activity
GO:0005254	chloride channel activity
GO:0008271	secondary active sulfate transmembrane transporter activity
GO:0015106	bicarbonate transmembrane transporter activity
GO:0015108	chloride transmembrane transporter activity
GO:0015297	antiporter activity
GO:0015301	anion:anion antiporter activity
GO:0019531	oxalate transmembrane transporter activity

Vocabulary: **biological process**
Term	Definition
GO:0008272	sulfate transport
GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0015701	bicarbonate transport
GO:0019532	oxalate transport
GO:0042391	regulation of membrane potential
GO:0051453	regulation of intracellular pH
GO:0055085	transmembrane transport
GO:1902358	sulfate transmembrane transport
GO:1902476	chloride transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR011547	SLC26A/SulP transporter domain	PFAM	PF00916	Sulfate_transp	coord: 96..205 e-value: 2.5E-23 score: 82.5
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..20
None	No IPR available	PANTHER	PTHR11814:SF180	ANION TRANSPORTER SULP-4	coord: 33..204
None	No IPR available	TMHMM	TMhelix		coord: 94..111
None	No IPR available	TMHMM	TMhelix		coord: 121..143
IPR001902	SLC26A/SulP transporter	PANTHER	PTHR11814	SULFATE TRANSPORTER	coord: 33..204

Main menu

slc26a-4

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

blazegraph-runner