Oxysterol-binding protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031216 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 442.58 bits (1137), Expect = 2.082e-145 Identity = 233/422 (55.21%), Postives = 283/422 (67.06%), Query Frame = 2
Query: 1499 LKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXX---XXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
L A VP S+KV+ RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR DD+G RSL EQVSHHPP+A+ + S GW WQE T+SSKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +KV+H D + V++T A+ LW + PE MY F+ AL LNE EE VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR R + S+ + + P+WF D T +Y G YWE K W
Sbjct: 38 LDGASLVPKGSSKVK------RRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDW 453
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 448.358 bits (1152), Expect = 7.457e-145 Identity = 234/423 (55.32%), Postives = 283/423 (66.90%), Query Frame = 2
Query: 1499 LKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEE----HKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
L A VP S+KV+ RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR DD+G RSL EQVSHHPP+A+ + S GW WQE T+SSKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +KV+H D + V++T A+ LW + PE MY F+ AL LNE EE VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR R + S E+ + P+WF D T +Y G YWE K W
Sbjct: 236 LDGASLVPKGSSKVK------RRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEAEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDW 652
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 444.121 bits (1141), Expect = 9.028e-145 Identity = 233/422 (55.21%), Postives = 283/422 (67.06%), Query Frame = 2
Query: 1499 LKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXX---XXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
L A VP S+KV+ RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR DD+G RSL EQVSHHPP+A+ + S GW WQE T+SSKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +KV+H D + V++T A+ LW + PE MY F+ AL LNE EE VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR R + S+ + + P+WF D T +Y G YWE K W
Sbjct: 127 LDGASLVPKGSSKVK------RRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDW 542
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 444.506 bits (1142), Expect = 2.420e-144 Identity = 233/422 (55.21%), Postives = 283/422 (67.06%), Query Frame = 2
Query: 1499 LKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXX---XXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
L A VP S+KV+ RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR DD+G RSL EQVSHHPP+A+ + S GW WQE T+SSKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +KV+H D + V++T A+ LW + PE MY F+ AL LNE EE VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR R + S+ + + P+WF D T +Y G YWE K W
Sbjct: 166 LDGASLVPKGSSKVK------RRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDW 581
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 446.047 bits (1146), Expect = 2.533e-144 Identity = 233/422 (55.21%), Postives = 283/422 (67.06%), Query Frame = 2
Query: 1499 LKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXX---XXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
L A VP S+KV+ RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR DD+G RSL EQVSHHPP+A+ + S GW WQE T+SSKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +KV+H D + V++T A+ LW + PE MY F+ AL LNE EE VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR R + S+ + + P+WF D T +Y G YWE K W
Sbjct: 214 LDGASLVPKGSSKVK------RRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDW 629
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 418.313 bits (1074), Expect = 3.229e-134 Identity = 223/400 (55.75%), Postives = 287/400 (71.75%), Query Frame = 2
Query: 1547 KPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKV--LHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
K R RRT + RPN+ INLW IMKNCIGKELSKIP+PVNF+EP+S++QR+TED EY++ L+ A+ + +LEQ+ +VAA+ S+YSTT +RT KPFNPLLGETFEFDR DDLGWRS+ EQVSHHPPAA+ H E GW +Q+FTM+S+FRGKYL++IP+G H+ F + +H+++RK+T+TVHNIIVGKLWIDNHG+M+I NH+T E C L + YSYFS+E R+V G++ D +G+ KYV+ GTWD KV + +K +V ET + +W+ P+ +M+NFT A+ELNEPEE VAPTDSRLRPDQRLME G WDEAN++K +EEKQR RR RE E E +G EE++P WF V DE H + G YWE K W
Sbjct: 225 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEG-NGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETS-LKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKG-DKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNW 620
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 411.379 bits (1056), Expect = 5.538e-134 Identity = 223/400 (55.75%), Postives = 287/400 (71.75%), Query Frame = 2
Query: 1547 KPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKV--LHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
K R RRT + RPN+ INLW IMKNCIGKELSKIP+PVNF+EP+S++QR+TED EY++ L+ A+ + +LEQ+ +VAA+ S+YSTT +RT KPFNPLLGETFEFDR DDLGWRS+ EQVSHHPPAA+ H E GW +Q+FTM+S+FRGKYL++IP+G H+ F + +H+++RK+T+TVHNIIVGKLWIDNHG+M+I NH+T E C L + YSYFS+E R+V G++ D +G+ KYV+ GTWD KV + +K +V ET + +W+ P+ +M+NFT A+ELNEPEE VAPTDSRLRPDQRLME G WDEAN++K +EEKQR RR RE E E +G EE++P WF V DE H + G YWE K W
Sbjct: 47 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEG-NGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETS-LKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKG-DKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNW 442
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 420.239 bits (1079), Expect = 1.426e-133 Identity = 223/400 (55.75%), Postives = 287/400 (71.75%), Query Frame = 2
Query: 1547 KPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKV--LHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
K R RRT + RPN+ INLW IMKNCIGKELSKIP+PVNF+EP+S++QR+TED EY++ L+ A+ + +LEQ+ +VAA+ S+YSTT +RT KPFNPLLGETFEFDR DDLGWRS+ EQVSHHPPAA+ H E GW +Q+FTM+S+FRGKYL++IP+G H+ F + +H+++RK+T+TVHNIIVGKLWIDNHG+M+I NH+T E C L + YSYFS+E R+V G++ D +G+ KYV+ GTWD KV + +K +V ET + +W+ P+ +M+NFT A+ELNEPEE VAPTDSRLRPDQRLME G WDEAN++K +EEKQR RR RE E E +G EE++P WF V DE H + G YWE K W
Sbjct: 330 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEG-NGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETS-LKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKG-DKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNW 725 HSP 2 Score: 105.145 bits (261), Expect = 7.955e-23 Identity = 48/102 (47.06%), Postives = 70/102 (68.63%), Query Frame = 2
Query: 92 GYLYKWTNYIKGYQKRWFVL-SNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDD 394
G+L KWTNY+KGY++RWFVL SN LSYYRN +EV HTCRG+INL + + + S ++ + +QTFH+K Q+E + QW +L + AI+ +E+ D+
Sbjct: 31 GWLNKWTNYLKGYRQRWFVLDSNATLSYYRNPSEVGHTCRGSINLQEARVHTDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRAESEEDE 132
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 419.853 bits (1078), Expect = 4.912e-133 Identity = 223/400 (55.75%), Postives = 287/400 (71.75%), Query Frame = 2
Query: 1547 KPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKV--LHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
K R RRT + RPN+ INLW IMKNCIGKELSKIP+PVNF+EP+S++QR+TED EY++ L+ A+ + +LEQ+ +VAA+ S+YSTT +RT KPFNPLLGETFEFDR DDLGWRS+ EQVSHHPPAA+ H E GW +Q+FTM+S+FRGKYL++IP+G H+ F + +H+++RK+T+TVHNIIVGKLWIDNHG+M+I NH+T E C L + YSYFS+E R+V G++ D +G+ KYV+ GTWD KV + +K +V ET + +W+ P+ +M+NFT A+ELNEPEE VAPTDSRLRPDQRLME G WDEAN++K +EEKQR RR RE E E +G EE++P WF V DE H + G YWE K W
Sbjct: 364 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEG-NGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETS-LKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKG-DKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNW 759 HSP 2 Score: 105.145 bits (261), Expect = 8.442e-23 Identity = 48/102 (47.06%), Postives = 70/102 (68.63%), Query Frame = 2
Query: 92 GYLYKWTNYIKGYQKRWFVL-SNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDD 394
G+L KWTNY+KGY++RWFVL SN LSYYRN +EV HTCRG+INL + + + S ++ + +QTFH+K Q+E + QW +L + AI+ +E+ D+
Sbjct: 65 GWLNKWTNYLKGYRQRWFVLDSNATLSYYRNPSEVGHTCRGSINLQEARVHTDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRAESEEDE 166
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 421.394 bits (1082), Expect = 8.984e-133 Identity = 223/400 (55.75%), Postives = 287/400 (71.75%), Query Frame = 2
Query: 1547 KPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKV--LHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
K R RRT + RPN+ INLW IMKNCIGKELSKIP+PVNF+EP+S++QR+TED EY++ L+ A+ + +LEQ+ +VAA+ S+YSTT +RT KPFNPLLGETFEFDR DDLGWRS+ EQVSHHPPAA+ H E GW +Q+FTM+S+FRGKYL++IP+G H+ F + +H+++RK+T+TVHNIIVGKLWIDNHG+M+I NH+T E C L + YSYFS+E R+V G++ D +G+ KYV+ GTWD KV + +K +V ET + +W+ P+ +M+NFT A+ELNEPEE VAPTDSRLRPDQRLME G WDEAN++K +EEKQR RR RE E E +G EE++P WF V DE H + G YWE K W
Sbjct: 440 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLS-TLEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEG-NGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETS-LKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKG-DKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNW 835 HSP 2 Score: 60.077 bits (144), Expect = 8.290e-9 Identity = 27/73 (36.99%), Postives = 45/73 (61.64%), Query Frame = 2
Query: 176 RNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDD 394
RN +EV HTCRG+INL + + + S ++ + +QTFH+K Q+E + QW +L + AI+ +E+ D+
Sbjct: 170 RNPSEVGHTCRGSINLQEARVHTDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRAESEEDE 242
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: Osbp (gene:FBgn0020626 transcript:FBtr0084801) HSP 1 Score: 432.18 bits (1110), Expect = 1.765e-137 Identity = 224/392 (57.14%), Postives = 282/392 (71.94%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKT--GETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKAT 2731
RR ++ +PN I+LWGIMKNCIGK+LSKIP+P+NFNEPLSM+QRL ED+EY++ LD AA C D EQL+++AAFTVS+Y+TTTNRTGKPFNPLLGET+E DR DD GWR LAEQVSHHPP A+LHCES K W CWQEF+M+SKFRGKY+ I P+G ++ F S Y+WRKVT+TV+NIIVGKLW+D HGEM+I + G C LN+ YSYFS++ R V GV+ +KD K+V+ GTWD + A VL ++ + TG + W RR P + + YNFT A +LNE EE VAPTDSRLRPDQRLME G WDE+NKEK RLEEKQR +RR RE E E+ ++ P ++P+WF +E ++ H++ YWE KA
Sbjct: 386 RRDRVPDKPNHPISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCES-KNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSVSS-PTYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERRRRENEAEEAAAE-GRPYPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAA 774 HSP 2 Score: 131.724 bits (330), Expect = 5.644e-31 Identity = 59/93 (63.44%), Postives = 73/93 (78.49%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAI 367
KG+L KWTNYIKGYQ+RWFVLS G+LSYYRN++E++HTCRGTI+L ++I DS + VISN QTFH+KA +E E W+TAL LAK AI
Sbjct: 18 KGWLLKWTNYIKGYQRRWFVLSKGVLSYYRNQSEINHTCRGTISLHGALIHTVDSCTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAI 110
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG3860 (gene:FBgn0034951 transcript:FBtr0343288) HSP 1 Score: 199.519 bits (506), Expect = 3.071e-55 Identity = 102/230 (44.35%), Postives = 139/230 (60.43%), Query Frame = 2
Query: 1598 INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTW 2287
+++W I+KNCIGK+LSKI +PV NEPLS +QRL E EY+ L AA+ +++ +VAAF VS+ ++ R GKPFNPLLGET+E + D +R + EQVSHHPP ++ H ES K +K + KF GK + + P G + F K N Y+W V VHNIIVG+LWI+ +G+M+I NH TG L +K+ +K RV G + D Y L G W
Sbjct: 25 VSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGD---YRIVCEQVSHHPPVSAFHAES-KDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKN-LHRVEGFVKDASETNLYFLYGKW 249 HSP 2 Score: 56.9954 bits (136), Expect = 6.287e-8 Identity = 52/124 (41.94%), Postives = 66/124 (53.23%), Query Frame = 2
Query: 2372 TLWSRRFPPEYTSEMYNFTNFALELN------EPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETK 2725
TLWS + P SE Y FT+FAL+LN +P + PTDSRLRPD +E G D A+KEK RLEEKQR R+ R+ ++ P WF + TK +YSG YW+ K
Sbjct: 336 TLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNS----------DDWSPRWFKYATNPHTKIDDWLYSGGYWDRK 449
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG3860 (gene:FBgn0034951 transcript:FBtr0072201) HSP 1 Score: 199.519 bits (506), Expect = 3.137e-55 Identity = 102/230 (44.35%), Postives = 139/230 (60.43%), Query Frame = 2
Query: 1598 INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTW 2287
+++W I+KNCIGK+LSKI +PV NEPLS +QRL E EY+ L AA+ +++ +VAAF VS+ ++ R GKPFNPLLGET+E + D +R + EQVSHHPP ++ H ES K +K + KF GK + + P G + F K N Y+W V VHNIIVG+LWI+ +G+M+I NH TG L +K+ +K RV G + D Y L G W
Sbjct: 25 VSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGD---YRIVCEQVSHHPPVSAFHAES-KDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKN-LHRVEGFVKDASETNLYFLYGKW 249 HSP 2 Score: 56.9954 bits (136), Expect = 6.099e-8 Identity = 52/124 (41.94%), Postives = 66/124 (53.23%), Query Frame = 2
Query: 2372 TLWSRRFPPEYTSEMYNFTNFALELN------EPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETK 2725
TLWS + P SE Y FT+FAL+LN +P + PTDSRLRPD +E G D A+KEK RLEEKQR R+ R+ ++ P WF + TK +YSG YW+ K
Sbjct: 334 TLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNS----------DDWSPRWFKYATNPHTKIDDWLYSGGYWDRK 447
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG42668 (gene:FBgn0261550 transcript:FBtr0302666) HSP 1 Score: 94.3597 bits (233), Expect = 2.050e-19 Identity = 67/236 (28.39%), Postives = 111/236 (47.03%), Query Frame = 2
Query: 1604 LWGIMKNCI-GKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRS--LAEQVSHHPPAASLHCESIK-GWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVL---NGTWD 2290
+W I+K G +LSK+ +P EP S + +L++ + ++D L A + D+ ++ V + +SS+ KP+NP+LGE F G R+ +AEQVSHHPP ++ + + + G+ SKF G + + G A +T YT + I++G L ++ G+++I TG L +K + A T V+ K + K L NG WD
Sbjct: 106 IWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHPSGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADA---TNVVVGKIKLGKETLATINGHWD 338
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG42668 (gene:FBgn0261550 transcript:FBtr0306633) HSP 1 Score: 94.3597 bits (233), Expect = 3.003e-19 Identity = 67/236 (28.39%), Postives = 111/236 (47.03%), Query Frame = 2
Query: 1604 LWGIMKNC-IGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRS--LAEQVSHHPPAASLHCESIK-GWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVL---NGTWD 2290
+W I+K G +LSK+ +P EP S + +L++ + ++D L A + D+ ++ V + +SS+ KP+NP+LGE F G R+ +AEQVSHHPP ++ + + + G+ SKF G + + G A +T YT + I++G L ++ G+++I TG L +K + A T V+ K + K L NG WD
Sbjct: 471 IWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHPSGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADA---TNVVVGKIKLGKETLATINGHWD 703
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: si:ch211-106a19.1 (si:ch211-106a19.1 [Source:ZFIN;Acc:ZDB-GENE-060526-3]) HSP 1 Score: 458.373 bits (1178), Expect = 8.787e-151 Identity = 234/405 (57.78%), Postives = 285/405 (70.37%), Query Frame = 2
Query: 1541 EKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
E +P R RR++I+ +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA C +SLEQ+ VAAF+VSSYSTT +RT KPFNPLLGET+E DR ++ G+RSL EQVSHHPPAA+ H S +GW WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G++DI NH+T ETC L + YSYFS+E R+VTGV+ D DG Y+L+GTWD + AK++ + + V++T + LW + PE MY F++ AL LNE E+ V+ TDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE E + + E +KP WF DE T +Y G YWE K W
Sbjct: 111 ELQPRRKRRSRISEKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCENSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVVSQRGWSLWQEITIASKFRGKYLSIMPLGAIHLQFHASGNHYVWRKVTSTVHNIIVGKLWIDQSGDIDIVNHRTKETCQLKFSPYSYFSREVPRKVTGVVMDSDGQANYILSGTWDEKMESAKIVQSSRGSSSSEGKQKTVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEEEDGVSITDSRLRPDQRLMEAGRWDEANAEKQRLEEKQRAVRRRREAEASRAIDE--EDFEGYKPQWFHQTTDEMTGENIFVYKGGYWEAKDRQDW 513
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: si:ch211-106a19.1 (si:ch211-106a19.1 [Source:ZFIN;Acc:ZDB-GENE-060526-3]) HSP 1 Score: 459.529 bits (1181), Expect = 4.050e-150 Identity = 234/405 (57.78%), Postives = 285/405 (70.37%), Query Frame = 2
Query: 1541 EKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
E +P R RR++I+ +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA C +SLEQ+ VAAF+VSSYSTT +RT KPFNPLLGET+E DR ++ G+RSL EQVSHHPPAA+ H S +GW WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G++DI NH+T ETC L + YSYFS+E R+VTGV+ D DG Y+L+GTWD + AK++ + + V++T + LW + PE MY F++ AL LNE E+ V+ TDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE E + + E +KP WF DE T +Y G YWE K W
Sbjct: 195 ELQPRRKRRSRISEKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCENSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVVSQRGWSLWQEITIASKFRGKYLSIMPLGAIHLQFHASGNHYVWRKVTSTVHNIIVGKLWIDQSGDIDIVNHRTKETCQLKFSPYSYFSREVPRKVTGVVMDSDGQANYILSGTWDEKMESAKIVQSSRGSSSSEGKQKTVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEEEDGVSITDSRLRPDQRLMEAGRWDEANAEKQRLEEKQRAVRRRREAEASRAIDE--EDFEGYKPQWFHQTTDEMTGENIFVYKGGYWEAKDRQDW 597 HSP 2 Score: 55.8398 bits (133), Expect = 2.138e-7 Identity = 34/114 (29.82%), Postives = 60/114 (52.63%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQ-SESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F A ++Q++L EREQR LE+ +E+LAKQ +LE+ + ++S P+ ++ASD+ +D ++DA+ED F
Sbjct: 70 ERATLFRITSNAMINACRDFLELAESHSRRWQRVLQHEREQRTHLEETIEQLAKQHNSLERAWREAPAQSFIFFYERPR------------KEEASDEDEDTEYFDAMEDSPAF 171
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: si:ch211-106a19.1 (si:ch211-106a19.1 [Source:ZFIN;Acc:ZDB-GENE-060526-3]) HSP 1 Score: 462.996 bits (1190), Expect = 7.865e-149 Identity = 235/405 (58.02%), Postives = 287/405 (70.86%), Query Frame = 2
Query: 1541 EKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
E +P R RR++I+ +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA C +SLEQ+ VAAF+VSSYSTT +RT KPFNPLLGET+E DR ++ G+RSL EQVSHHPPAA+ H S +GW WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G++DI NH+T ETC L + YSYFS+E R+VTGV+ D DG Y+L+GTWD + AK++ + + V++T + LW + PE MY F++ AL LNE E+ V+ TDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE E + +G E +KP+WF DE T +Y G YWE K W
Sbjct: 398 ELQPRRKRRSRISEKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCENSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVVSQRGWSLWQEITIASKFRGKYLSIMPLGAIHLQFHASGNHYVWRKVTSTVHNIIVGKLWIDQSGDIDIVNHRTKETCQLKFSPYSYFSREVPRKVTGVVMDSDGQANYILSGTWDEKMESAKIVQSSRGSSSSEGKQKTVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEEEDGVSITDSRLRPDQRLMEAGRWDEANAEKQRLEEKQRAVRRRREAEASRAIDEG-EDFEGYKPLWFHQTTDEMTGENIFVYKGGYWEAKDRQDW 801 HSP 2 Score: 138.658 bits (348), Expect = 4.828e-33 Identity = 76/169 (44.97%), Postives = 100/169 (59.17%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKK 586
D +KG+L+KWTNYIKGYQ+RWFVLSNGLLSYYR + E++HTCRGTINL+T+ I +D+ +IV+S+ +T+HLKA +E E +W+TAL LAK AI + DDS E P SD S+I K +L DL+T L+ K
Sbjct: 71 DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLATAHIDTEDACNIVLSS-GGRTYHLKASTEVERQRWVTALELAKAKAIRMMNDQSDDSADEEPTS--------------------------QSDHSEIQGTLKTLASKLDDLSTCNELIAK 212 HSP 3 Score: 62.003 bits (149), Expect = 3.143e-9 Identity = 38/113 (33.63%), Postives = 65/113 (57.52%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F A ++Q++L EREQR LE+ +E+LAKQ +LE +A +++ + +NT +D + R + + + +D D EYF DA+ED F
Sbjct: 242 ERATLFRITSNAMINACRDFLELAESHSRRWQRVLQHEREQRTHLEETIEQLAKQHNSLE-RAWREAPAHAVNTPDTPTTDTGVSERPRKEEASDEDEDTEYF-DAMEDSPAF 352
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: si:ch211-106a19.1 (si:ch211-106a19.1 [Source:ZFIN;Acc:ZDB-GENE-060526-3]) HSP 1 Score: 449.129 bits (1154), Expect = 1.572e-148 Identity = 231/398 (58.04%), Postives = 281/398 (70.60%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
RR++I+ +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA C +SLEQ+ VAAF+VSSYSTT +RT KPFNPLLGET+E DR ++ G+RSL EQVSHHPPAA+ H S +GW WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G++DI NH+T ETC L + YSYFS+E R+VTGV+ D DG Y+L+GTWD + AK++ + + V++T + LW + PE MY F++ AL LNE E+ V+ TDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE E + + E +KP WF DE T +Y G YWE K W
Sbjct: 33 RRSRISEKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCENSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVVSQRGWSLWQEITIASKFRGKYLSIMPLGAIHLQFHASGNHYVWRKVTSTVHNIIVGKLWIDQSGDIDIVNHRTKETCQLKFSPYSYFSREVPRKVTGVVMDSDGQANYILSGTWDEKMESAKIVQSSRGSSSSEGKQKTVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEEEDGVSITDSRLRPDQRLMEAGRWDEANAEKQRLEEKQRAVRRRREAEASRAIDE--EDFEGYKPQWFHQTTDEMTGENIFVYKGGYWEAKDRQDW 428
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbp (oxysterol binding protein [Source:ZFIN;Acc:ZDB-GENE-090312-18]) HSP 1 Score: 454.907 bits (1169), Expect = 3.123e-146 Identity = 254/444 (57.21%), Postives = 307/444 (69.14%), Query Frame = 2
Query: 1466 NVSG--------DVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRK------DKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIE-----EHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
NVSG D +T + ++ S P E P R RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRL+ED EY + LD A+C SLEQ+ +VAAFTVSSYSTT +RTGKPFNPLLGETFE DR + G+RSL EQVSHHPPAA+ H S +GW QE ++SKFRGKYL+I+P+G H FEKSNNHYTW+KVT+TVHNIIVGKLWID GE+DI NH+TG+ CHL + YSYFS++ AR+VTGV+TDKDG YVL+GTWD + ++V+ + D + V++T A+ LW + PE MY F+ AL LNEPEE VAPTDSR RPDQRLME G W+EAN EK+RLEEKQR RR RE+E + + P E +K +WF D T THIY G YWETK G W
Sbjct: 314 NVSGISSEMGMDDGTTSLDEQSMASNPESPQSQEVVPVRKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLSEDLEYYELLDRGAKCQSSLEQMCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHAISERGWTLRQEIALASKFRGKYLSIMPLGSIHCIFEKSNNHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGADGRQKTVYQTLKAKELWRKTPLPEGAENMYYFSTLALTLNEPEEGVAPTDSRKRPDQRLMEQGRWEEANAEKQRLEEKQRTARREREREANRSAN----PEEGGHQDSYKAMWFDRCVDPMTGEPTHIYRGGYWETKEQGNW 753 HSP 2 Score: 144.05 bits (362), Expect = 8.553e-35 Identity = 67/120 (55.83%), Postives = 83/120 (69.17%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNS 439
D +KG+L+KWTNYIKGYQ+RWFVLSNGLLSYYR + E+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A + D D P + G +
Sbjct: 13 DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGTQTYHLKASSEVERQRWITALELAKAKAFRMQAESDDSGDESTPPAAGQGGGA 132 HSP 3 Score: 63.5438 bits (153), Expect = 1.015e-9 Identity = 42/129 (32.56%), Postives = 70/129 (54.26%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLP 1159
G + + + E+ F + + A +N+C +F A ++QK L EREQR+RLE+ +E+LAKQ LE +A + + + + S P + D K V ASD+ ++ F+DA ED F +++P
Sbjct: 179 GETSEKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAEREQRVRLEETLEQLAKQHNHLE-RAFRGATVLPPSQSNP--AIDSKG-SVPGKGDASDEDEENEFFDACEDVQEF-ITVP 302
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: ccdc6 (coiled-coil domain containing 6 [Source:Xenbase;Acc:XB-GENE-978266]) HSP 1 Score: 450.669 bits (1158), Expect = 2.596e-144 Identity = 235/409 (57.46%), Postives = 289/409 (70.66%), Query Frame = 2
Query: 1529 STKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIR-----KDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
S + E P + RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD A +C S+EQ+ ++AAF+VSSYSTT +RT KPFNPLLGETFE DR DDLG+RS+ EQVSHHPPAA+ + S GWK WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G+++I N+KT + C L + YSYFS++ AR+VTGV+TD +G YVL+GTWD + AK++ + + V++T P + LW + PE MY F+ FAL LNE +E+VAPTDSR RPDQRLME G WDEAN EK+RLEEKQR RR RE E + +G E ++P+WF D T Y G YWE K W
Sbjct: 363 SKRKELIPKKRRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAVKCESSIEQMCFIAAFSVSSYSTTVHRTAKPFNPLLGETFELDRLDDLGFRSICEQVSHHPPAAAHYVHSKNGWKLWQEITIASKFRGKYLSIMPLGDIHLEFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIINYKTKDKCQLKFSPYSYFSRDIARKVTGVVTDANGKAHYVLSGTWDEKMECAKIVQSSHGNSCAEGKQKTVYQTLPPKLLWKKYPLPENAENMYFFSEFALTLNESDESVAPTDSRNRPDQRLMENGKWDEANVEKQRLEEKQRAVRRRREAEAVEALEEG-NDYEGYQPLWFERKVDPYTGELICNYKGGYWECKERQDW 770 HSP 2 Score: 131.339 bits (329), Expect = 1.368e-30 Identity = 66/111 (59.46%), Postives = 85/111 (76.58%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
D +KG+L+KWTNY+KGYQ+RWFVLSNGLLSYYR + E++HTCRGTINLST+ I +DS +IV++N +T+HLKA E E +W+TAL LAK A L+E +DS E P
Sbjct: 69 DTYKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLSTAHIDTEDSCNIVLTN-GGRTYHLKASCEVERQRWVTALELAK--AKLLAE---NDSGDEEP 173 HSP 3 Score: 62.003 bits (149), Expect = 4.630e-9 Identity = 36/113 (31.86%), Postives = 65/113 (57.52%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F + A K+ + L EREQR+RLE+ +E+LAKQ +LE +A + + + NT+ ++ +K +ASD+ ++ ++DA+ED F
Sbjct: 235 ERATLFRITSNAMINACRDFLDLAETHSRKWHRALQYEREQRVRLEETIEQLAKQHNSLE-RACRGAPGLTSNTTGVLNTPKGNVPAIKG--EASDEDEETEYFDAMEDAPAF 344
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: ccdc6 (coiled-coil domain containing 6 [Source:Xenbase;Acc:XB-GENE-978266]) HSP 1 Score: 447.203 bits (1149), Expect = 3.269e-143 Identity = 235/436 (53.90%), Postives = 296/436 (67.89%), Query Frame = 2
Query: 1457 DLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIR-----KDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXX---XXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
D +++ +VS F+ +S + E P + RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD A +C S+EQ+ ++AAF+VSSYSTT +RT KPFNPLLGETFE DR DDLG+RS+ EQVSHHPPAA+ + S GWK WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G+++I N+KT + C L + YSYFS++ AR+VTGV+TD +G YVL+GTWD + AK++ + + V++T P + LW + PE MY F+ FAL LNE +E+VAPTDSR RPDQRLME G WDEAN EK+RLEEKQ R +R E + +Q ++P+WF D T Y G YWE K W
Sbjct: 324 DDWHLEDNVSIFAVCNNHES-----KRKELIPKKRRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAVKCESSIEQMCFIAAFSVSSYSTTVHRTAKPFNPLLGETFELDRLDDLGFRSICEQVSHHPPAAAHYVHSKNGWKLWQEITIASKFRGKYLSIMPLGDIHLEFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIINYKTKDKCQLKFSPYSYFSRDIARKVTGVVTDANGKAHYVLSGTWDEKMECAKIVQSSHGNSCAEGKQKTVYQTLPPKLLWKKYPLPENAENMYFFSEFALTLNESDESVAPTDSRNRPDQRLMENGKWDEANVEKQRLEEKQRAVRRRREAEAVEALEEVNQRSESPNRYQPLWFERKVDPYTGELICNYKGGYWECKERQDW 754 HSP 2 Score: 139.428 bits (350), Expect = 3.654e-33 Identity = 66/111 (59.46%), Postives = 84/111 (75.68%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
D +KG+L+KWTNY+KGYQ+RWFVLSNGLLSYYR + E++HTCRGTINLST+ I +DS +IV++N +T+HLKA E E +W+TAL LAK AI + DDS E P
Sbjct: 18 DTYKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLSTAHIDTEDSCNIVLTN-GGRTYHLKASCEVERQRWVTALELAKAKAIRMMNNQSDDSGDEEP 127 HSP 3 Score: 61.6178 bits (148), Expect = 5.922e-9 Identity = 36/113 (31.86%), Postives = 65/113 (57.52%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F + A K+ + L EREQR+RLE+ +E+LAKQ +LE +A + + + NT+ ++ +K +ASD+ ++ ++DA+ED F
Sbjct: 189 ERATLFRITSNAMINACRDFLDLAETHSRKWHRALQYEREQRVRLEETIEQLAKQHNSLE-RACRGAPGLTSNTTGVLNTPKGNVPAIKG--EASDEDEETEYFDAMEDAPAF 298
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBP (oxysterol binding protein [Source:NCBI gene;Acc:100488223]) HSP 1 Score: 419.083 bits (1076), Expect = 1.154e-132 Identity = 229/395 (57.97%), Postives = 269/395 (68.10%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
RRT+I +PN S+NLW +MKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY LD A+C +LEQL VAAFTVSSYSTT RT KPFNPLLGETFE DR ++ G+RSL EQVSHHPPAA+ H ES GW QE T++SKFRGKYL+I+P+G H F S NHYTW+KVT+TVHNIIVGKLWID E+DI NHKTG+ C L + YSYFS++ AR+V+G + D G Y L GTWD + V + N LW R P+ MY FT FAL LN PEE AP+DSR RPDQRLME G WDEAN EK+RLEEKQR R+ RE E E+ G P++ +KP+WF D +K THI G YWE K W +
Sbjct: 342 RRTRIPYKPNYSLNLWSVMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHTLLDRGAQCESALEQLCLVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRMEESGYRSLCEQVSHHPPAAAHHAESRHGWTLRQEITVTSKFRGKYLSIMPLGTIHCVFHNSGNHYTWKKVTTTVHNIIVGKLWIDQEREIDIVNHKTGDRCKLKFAPYSYFSRDVARKVSGEVMDATGRVHYTLMGTWDERMECIPVYSVSTVSENGGDKAADNKILLWKRNPLPKNAEYMYYFTEFALTLNAPEEGTAPSDSRHRPDQRLMENGNWDEANSEKQRLEEKQRNTRKKREAERERAGEDG-SPVDTYKPMWFERKMDPVSKEMTHICRGIYWECKERQDWAS 735 HSP 2 Score: 80.4925 bits (197), Expect = 8.129e-15 Identity = 42/78 (53.85%), Postives = 54/78 (69.23%), Query Frame = 2
Query: 179 NKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
+K E+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ + +A DDS E P
Sbjct: 66 SKAEMRHTCRGTINLATANISVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKARAVKM-QAESDDSGDEDP 142
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBP (oxysterol binding protein [Source:NCBI gene;Acc:100488223]) HSP 1 Score: 416.772 bits (1070), Expect = 1.790e-132 Identity = 229/395 (57.97%), Postives = 269/395 (68.10%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
RRT+I +PN S+NLW +MKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY LD A+C +LEQL VAAFTVSSYSTT RT KPFNPLLGETFE DR ++ G+RSL EQVSHHPPAA+ H ES GW QE T++SKFRGKYL+I+P+G H F S NHYTW+KVT+TVHNIIVGKLWID E+DI NHKTG+ C L + YSYFS++ AR+V+G + D G Y L GTWD + V + N LW R P+ MY FT FAL LN PEE AP+DSR RPDQRLME G WDEAN EK+RLEEKQR R+ RE E E+ G P++ +KP+WF D +K THI G YWE K W +
Sbjct: 293 RRTRIPYKPNYSLNLWSVMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHTLLDRGAQCESALEQLCLVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRMEESGYRSLCEQVSHHPPAAAHHAESRHGWTLRQEITVTSKFRGKYLSIMPLGTIHCVFHNSGNHYTWKKVTTTVHNIIVGKLWIDQEREIDIVNHKTGDRCKLKFAPYSYFSRDVARKVSGEVMDATGRVHYTLMGTWDERMECIPVYSVSTVSENGGDKAADNKILLWKRNPLPKNAEYMYYFTEFALTLNAPEEGTAPSDSRHRPDQRLMENGNWDEANSEKQRLEEKQRNTRKKREAERERAGEDG-SPVDTYKPMWFERKMDPVSKEMTHICRGIYWECKERQDWAS 686 HSP 2 Score: 82.8037 bits (203), Expect = 1.729e-15 Identity = 47/89 (52.81%), Postives = 59/89 (66.29%), Query Frame = 2
Query: 146 VLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
VLSN R+K E+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ + +A DDS E P
Sbjct: 3 VLSN----CKRSKAEMRHTCRGTINLATANISVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKARAVKM-QAESDDSGDEDP 86 HSP 3 Score: 51.2174 bits (121), Expect = 9.048e-6 Identity = 28/80 (35.00%), Postives = 46/80 (57.50%), Query Frame = 2
Query: 749 RAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEK 988
R P SS + + + E+ F + + A +N+C +F + A ++Q+ L ER+QRLRLE+ +E+LAKQ LE+
Sbjct: 134 RLPQESS-----EKIKQVNERATLFRITSNAMINACRDFMSLAESHSKRWQRALQYERDQRLRLEETLEQLAKQHNHLER 208
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBP (oxysterol binding protein [Source:NCBI gene;Acc:100488223]) HSP 1 Score: 417.157 bits (1071), Expect = 5.497e-132 Identity = 229/395 (57.97%), Postives = 269/395 (68.10%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
RRT+I +PN S+NLW +MKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY LD A+C +LEQL VAAFTVSSYSTT RT KPFNPLLGETFE DR ++ G+RSL EQVSHHPPAA+ H ES GW QE T++SKFRGKYL+I+P+G H F S NHYTW+KVT+TVHNIIVGKLWID E+DI NHKTG+ C L + YSYFS++ AR+V+G + D G Y L GTWD + V + N LW R P+ MY FT FAL LN PEE AP+DSR RPDQRLME G WDEAN EK+RLEEKQR R+ RE E E+ G P++ +KP+WF D +K THI G YWE K W +
Sbjct: 339 RRTRIPYKPNYSLNLWSVMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHTLLDRGAQCESALEQLCLVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRMEESGYRSLCEQVSHHPPAAAHHAESRHGWTLRQEITVTSKFRGKYLSIMPLGTIHCVFHNSGNHYTWKKVTTTVHNIIVGKLWIDQEREIDIVNHKTGDRCKLKFAPYSYFSRDVARKVSGEVMDATGRVHYTLMGTWDERMECIPVYSVSTVSENGGDKAADNKILLWKRNPLPKNAEYMYYFTEFALTLNAPEEGTAPSDSRHRPDQRLMENGNWDEANSEKQRLEEKQRNTRKKREAERERAGEDG-SPVDTYKPMWFERKMDPVSKEMTHICRGIYWECKERQDWAS 732 HSP 2 Score: 82.0333 bits (201), Expect = 2.797e-15 Identity = 44/101 (43.56%), Postives = 61/101 (60.40%), Query Frame = 2
Query: 110 TNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
+ +++G + L G R + + HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ + +A DDS E P
Sbjct: 32 STFLRGGSEFLAFLREGGAGESREQKAMRHTCRGTINLATANISVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKARAVKM-QAESDDSGDEDP 131 HSP 3 Score: 51.6026 bits (122), Expect = 6.941e-6 Identity = 28/80 (35.00%), Postives = 46/80 (57.50%), Query Frame = 2
Query: 749 RAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEK 988
R P SS + + + E+ F + + A +N+C +F + A ++Q+ L ER+QRLRLE+ +E+LAKQ LE+
Sbjct: 179 RLPQESS-----EKIKQVNERATLFRITSNAMINACRDFMSLAESHSKRWQRALQYERDQRLRLEETLEQLAKQHNHLER 253
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp2 (oxysterol binding protein 2 [Source:MGI Symbol;Acc:MGI:1921559]) HSP 1 Score: 441.039 bits (1133), Expect = 4.214e-145 Identity = 225/432 (52.08%), Postives = 289/432 (66.90%), Query Frame = 2
Query: 1472 SGDVSTFSELKTAQSVPSLSTKVEKKPARV-RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQ--VFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEE-----HKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
SG +T + +A +V ++ + K +V RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR +D+G RSL EQVSHHPP+A+ H S GW WQE T++SKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +K++H + +Q V++T PA+ LW R++P PE MY F+ AL LNE E+ VAPTDSRLRPDQRLME G WDEA +++ EK+R + + + G EE + P+WF D T +Y G YWE K W
Sbjct: 22 SGPGTTTVDWTSADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLW-RKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEA----NTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDW 448
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp2 (oxysterol binding protein 2 [Source:MGI Symbol;Acc:MGI:1921559]) HSP 1 Score: 440.269 bits (1131), Expect = 3.607e-144 Identity = 225/432 (52.08%), Postives = 289/432 (66.90%), Query Frame = 2
Query: 1472 SGDVSTFSELKTAQSVPSLSTKVEKKPARV-RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQ--VFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEE-----HKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
SG +T + +A +V ++ + K +V RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR +D+G RSL EQVSHHPP+A+ H S GW WQE T++SKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +K++H + +Q V++T PA+ LW R++P PE MY F+ AL LNE E+ VAPTDSRLRPDQRLME G WDEA +++ EK+R + + + G EE + P+WF D T +Y G YWE K W
Sbjct: 64 SGPGTTTVDWTSADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLW-RKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEA----NTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDW 490
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp2 (oxysterol binding protein 2 [Source:MGI Symbol;Acc:MGI:1921559]) HSP 1 Score: 445.277 bits (1144), Expect = 8.875e-141 Identity = 225/432 (52.08%), Postives = 289/432 (66.90%), Query Frame = 2
Query: 1472 SGDVSTFSELKTAQSVPSLSTKVEKKPARV-RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQ--VFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHK-----PVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
SG +T + +A +V ++ + K +V RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR +D+G RSL EQVSHHPP+A+ H S GW WQE T++SKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +K++H + +Q V++T PA+ LW R++P PE MY F+ AL LNE E+ VAPTDSRLRPDQRLME G WDEA +++ EK+R + + + G EE + P+WF D T +Y G YWE K W
Sbjct: 475 SGPGTTTVDWTSADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLW-RKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEA----NTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDW 901 HSP 2 Score: 126.716 bits (317), Expect = 4.359e-29 Identity = 56/98 (57.14%), Postives = 75/98 (76.53%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISL 373
D +KG+L KWTNY+KGYQ+RWFVL NGLLSYYRN+ E++HTCR TINL+++ +DS I++ N + +T+HLKA SE + W+TAL LAK AI +
Sbjct: 180 DSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRATINLASTHFETEDSCGILLCNGA-RTYHLKASSEVDRQHWITALELAKAKAIRV 276 HSP 3 Score: 53.9138 bits (128), Expect = 1.027e-6 Identity = 36/113 (31.86%), Postives = 57/113 (50.44%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F A K+Q+ LN E+EQR+ LE+ +E+LAKQ +LE+ + S E + + + +D D EYF DA+ED F
Sbjct: 353 ERATLFRITSNAMINACRDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPG----GPASSSKSFSEGSFLTSKGENSEEDEDTEYF-DAMEDSTSF 460
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp (oxysterol binding protein [Source:MGI Symbol;Acc:MGI:97447]) HSP 1 Score: 414.075 bits (1063), Expect = 4.095e-130 Identity = 230/399 (57.64%), Postives = 274/399 (68.67%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAE----TLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
+RT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA+C +SLEQL +VAAFTVSSYSTT RT KPFNPLLGETFE DR ++ G+RS+ EQVSHHPPAA+ H ES GW QE ++SKFRGKYL+I+P+G H F + +HYTW+KVT+TVHNIIVGKLWID GE+DI NHKTG+ C+L + YSYFS++ AR+VTG +TD G + L GTWD KV + AE LW R P+ MY F+ AL LN E APTDSRLRPDQRLME G WDEAN EK+RLEEKQR R+ RE E + G P + +K +WF D T+ THIYSG YWE K WG+
Sbjct: 403 KRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSICEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHSTGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQAASGENGGDARQRGHEAEDSRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAAKATEDGTPH-DPYKALWFERKKDPVTRELTHIYSGEYWECKEKQDWGS 800 HSP 2 Score: 138.658 bits (348), Expect = 4.810e-33 Identity = 64/107 (59.81%), Postives = 81/107 (75.70%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEA 409
+G+L+KWTNYIKGYQ+RWFVLSNGLLSYYR+K E+ HTCRGTINL+T+ I +DS + +ISN QT+HLKA SE E +W+TAL LAK A+ + D D E+
Sbjct: 90 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDDSGDEES 196 HSP 3 Score: 55.4546 bits (132), Expect = 3.319e-7 Identity = 36/113 (31.86%), Postives = 59/113 (52.21%), Query Frame = 2
Query: 791 MHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIE 1129
+ + E+ F + + A +N+C +F A K+QK L ER+QR+RLE+ +E+LAKQ LE +A + + + N P + K+ SD+ D+ F+DA E
Sbjct: 253 IKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLE-RAFRGATVLPANP--PGSAGSGKDQCCSGKGDMSDEDDENEFFDAPE 362
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbpl3 (oxysterol binding protein-like 3 [Source:MGI Symbol;Acc:MGI:1918970]) HSP 1 Score: 244.973 bits (624), Expect = 6.214e-68 Identity = 147/375 (39.20%), Postives = 218/375 (58.13%), Query Frame = 2
Query: 1442 DNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKI-TPRPNMS-INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTG-KPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCH--LNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAET--LWSRRFPPEYTSEMYNFTNFALELNEPE----ENVAPTDSRLRPDQRLMETGFWDEA 2533
DNL D N+S D+ +E +T V S + K RRT + P PN S ++LW I++N IGK+LSK+ +PV NEPL+ +QRL E+ EYS+ LD A+ LE++ +VAAF +S+Y+++ R G KPFNP+LGET+E R D G++ AEQVSHHPP ++ H ES + WQ+ +KF GK + I+P+G H+T +H+ W KVTS +HNI+ G+ WI+++GE+DI N ++CH +N+ Y+S A + G + D+ G + L G W ++ ++ G + + +W P+ + Y FT FALELNE + + PTD+R RPDQRL+E G +EA
Sbjct: 412 DNLSLD--NLSNDLD--NERQTLGPVLESSGEARSK----RRTSLPAPGPNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKASRIPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDK-GFQFFAEQVSHHPPISACHAES-GNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIKN-LNDDSCHCKVNFIKAKYWSTN-AHEIEGTVFDRSGKAVHRLFGKW-----------------HESIYCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEA 757
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q969R2|OSBP2_HUMAN (Oxysterol-binding protein 2 OS=Homo sapiens OX=9606 GN=OSBP2 PE=1 SV=2) HSP 1 Score: 445.277 bits (1144), Expect = 5.731e-140 Identity = 233/422 (55.21%), Postives = 283/422 (67.06%), Query Frame = 2
Query: 1499 LKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXX---XXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
L A VP S+KV+ RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR DD+G RSL EQVSHHPP+A+ + S GW WQE T+SSKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +KV+H D + V++T A+ LW + PE MY F+ AL LNE EE VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR R + S+ + + P+WF D T +Y G YWE K W
Sbjct: 494 LDGASLVPKGSSKVK------RRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDW 909 HSP 2 Score: 132.109 bits (331), Expect = 5.529e-30 Identity = 67/138 (48.55%), Postives = 93/138 (67.39%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRL 493
D +G+L KWTNY+KGYQ+RWFVL NGLLSYYRN+ E++HTCRGTINLST+ I +DS I++++ + +++HLKA SE + QW+TAL LAK A+ + DDS + +P + L HH+ L +D L
Sbjct: 183 DSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGA-RSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSEL---HHTLKNLSLKLDDL 316
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q5QNQ6|OSBP2_MOUSE (Oxysterol-binding protein 2 OS=Mus musculus OX=10090 GN=Osbp2 PE=1 SV=1) HSP 1 Score: 445.277 bits (1144), Expect = 6.208e-140 Identity = 225/432 (52.08%), Postives = 289/432 (66.90%), Query Frame = 2
Query: 1472 SGDVSTFSELKTAQSVPSLSTKVEKKPARV-RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQ--VFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHK-----PVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
SG +T + +A +V ++ + K +V RR +I +PN S+NLW IMKNCIG+ELS+IP+PVNFNEPLSM+QRLTED EY LD A C S+EQ+ VAAF+VSSYSTT +R KPFNP+LGETFE DR +D+G RSL EQVSHHPP+A+ H S GW WQE T++SKFRGKY++I+P+G HL F+ S NHY WRK TSTVHNIIVGKLWID G+++I NHKT + C L + YSYFSKE AR+VTGV++D G YVL+G+WD + +K++H + +Q V++T PA+ LW R++P PE MY F+ AL LNE E+ VAPTDSRLRPDQRLME G WDEA +++ EK+R + + + G EE + P+WF D T +Y G YWE K W
Sbjct: 475 SGPGTTTVDWTSADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLW-RKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEA----NTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDW 901 HSP 2 Score: 126.716 bits (317), Expect = 3.049e-28 Identity = 56/98 (57.14%), Postives = 75/98 (76.53%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISL 373
D +KG+L KWTNY+KGYQ+RWFVL NGLLSYYRN+ E++HTCR TINL+++ +DS I++ N + +T+HLKA SE + W+TAL LAK AI +
Sbjct: 180 DSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRATINLASTHFETEDSCGILLCNGA-RTYHLKASSEVDRQHWITALELAKAKAIRV 276 HSP 3 Score: 53.9138 bits (128), Expect = 7.186e-6 Identity = 36/113 (31.86%), Postives = 57/113 (50.44%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F A K+Q+ LN E+EQR+ LE+ +E+LAKQ +LE+ + S E + + + +D D EYF DA+ED F
Sbjct: 353 ERATLFRITSNAMINACRDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPG----GPASSSKSFSEGSFLTSKGENSEEDEDTEYF-DAMEDSTSF 460
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|P22059|OSBP1_HUMAN (Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1) HSP 1 Score: 414.075 bits (1063), Expect = 2.718e-129 Identity = 230/399 (57.64%), Postives = 274/399 (68.67%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAE----TLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
+RT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA+C +SLEQL +VAAFTVSSYSTT RT KPFNPLLGETFE DR ++ G+RSL EQVSHHPPAA+ H ES GW QE ++SKFRGKYL+I+P+G H F + +HYTW+KVT+TVHNIIVGKLWID GE+DI NHKTG+ C+L + YSYFS++ AR+VTG +TD G + L GTWD + KV + + AE LW R P+ MY F+ AL LN E APTDSRLRPDQRLME G WDEAN EK+RLEEKQR R+ RE E + G P + +K +WF D TK THIY G YWE K W +
Sbjct: 405 KRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDG-TPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWSS 802 HSP 2 Score: 137.502 bits (345), Expect = 7.971e-32 Identity = 72/144 (50.00%), Postives = 94/144 (65.28%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDIS 520
+G+L+KWTNYIKGYQ+RWFVLSNGLLSYYR+K E+ HTCRGTINL+T+ I +DS + +ISN QT+HLKA SE E +W+TAL LAK A+ + + D E S+++ + QN L R SS D+S
Sbjct: 92 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEE----------SVSQTDKTELQNTL---RTLSSKVEDLS 222 HSP 3 Score: 57.7658 bits (138), Expect = 5.461e-7 Identity = 37/113 (32.74%), Postives = 60/113 (53.10%), Query Frame = 2
Query: 791 MHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIE 1129
+ + E+ F + + A +N+C +F A K+QK L ER+QR+RLE+ +E+LAKQ LE +A + + + NT P + K+ SD+ D+ F+DA E
Sbjct: 255 IKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLE-RAFRGATVLPANT--PGNVGSGKDQCCSGKGDMSDEDDENEFFDAPE 364
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q3B7Z2|OSBP1_MOUSE (Oxysterol-binding protein 1 OS=Mus musculus OX=10090 GN=Osbp PE=1 SV=3) HSP 1 Score: 414.075 bits (1063), Expect = 2.864e-129 Identity = 230/399 (57.64%), Postives = 274/399 (68.67%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAE----TLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
+RT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA+C +SLEQL +VAAFTVSSYSTT RT KPFNPLLGETFE DR ++ G+RS+ EQVSHHPPAA+ H ES GW QE ++SKFRGKYL+I+P+G H F + +HYTW+KVT+TVHNIIVGKLWID GE+DI NHKTG+ C+L + YSYFS++ AR+VTG +TD G + L GTWD KV + AE LW R P+ MY F+ AL LN E APTDSRLRPDQRLME G WDEAN EK+RLEEKQR R+ RE E + G P + +K +WF D T+ THIYSG YWE K WG+
Sbjct: 403 KRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSICEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHSTGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQAASGENGGDARQRGHEAEDSRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAAKATEDGTPH-DPYKALWFERKKDPVTRELTHIYSGEYWECKEKQDWGS 800 HSP 2 Score: 138.658 bits (348), Expect = 3.365e-32 Identity = 64/107 (59.81%), Postives = 81/107 (75.70%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEA 409
+G+L+KWTNYIKGYQ+RWFVLSNGLLSYYR+K E+ HTCRGTINL+T+ I +DS + +ISN QT+HLKA SE E +W+TAL LAK A+ + D D E+
Sbjct: 90 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDDSGDEES 196 HSP 3 Score: 55.4546 bits (132), Expect = 2.322e-6 Identity = 36/113 (31.86%), Postives = 59/113 (52.21%), Query Frame = 2
Query: 791 MHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIE 1129
+ + E+ F + + A +N+C +F A K+QK L ER+QR+RLE+ +E+LAKQ LE +A + + + N P + K+ SD+ D+ F+DA E
Sbjct: 253 IKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLE-RAFRGATVLPANP--PGSAGSGKDQCCSGKGDMSDEDDENEFFDAPE 362
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|P16258|OSBP1_RABIT (Oxysterol-binding protein 1 OS=Oryctolagus cuniculus OX=9986 GN=OSBP PE=1 SV=1) HSP 1 Score: 413.305 bits (1061), Expect = 5.669e-129 Identity = 230/399 (57.64%), Postives = 273/399 (68.42%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAE----TLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
+RT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA+C +SLEQL +VAAFTVSSYSTT RT KPFNPLLGETFE DR ++ G+RSL EQVSHHPPAA+ H ES GW QE ++SKFRGKYL+I+P+G H F + +HYTW+KVT+TVHNIIVGKLWID GE+DI NHKTG+ C+L + YSYFS++ AR+VTG +TD G + L GTWD KV + + AE LW R P+ MY F+ AL LN E APTDSRLRPDQRLME G WDEAN EK+RLEEKQR R+ RE E + G P + +K +WF D TK THIY G YWE K W +
Sbjct: 407 KRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQPVSGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDG-TPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWNS 804 HSP 2 Score: 137.502 bits (345), Expect = 9.387e-32 Identity = 72/144 (50.00%), Postives = 94/144 (65.28%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDIS 520
+G+L+KWTNYIKGYQ+RWFVLSNGLLSYYR+K E+ HTCRGTINL+T+ I +DS + +ISN QT+HLKA SE E +W+TAL LAK A+ + + D E S+++ + QN L R SS D+S
Sbjct: 94 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEE----------SVSQTDKTELQNTL---RTLSSKVEDLS 224 HSP 3 Score: 55.4546 bits (132), Expect = 2.599e-6 Identity = 38/117 (32.48%), Postives = 60/117 (51.28%), Query Frame = 2
Query: 791 MHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDE----KNVRVKNTDQASDDSDDEYFYDAIE 1129
+ + E+ F + + A +N+C +F A K+QK L ER+QR+RLE+ +E+LAKQ LE +A + + T LP H+ K+ SD+ D+ F+DA E
Sbjct: 257 IKQVNERATLFRITSNAMINACRDFLVLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLE-RAFRGA------TVLPAHTSGSAGSGKDQCCSGKGDMSDEDDENEFFDAPE 366
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A1S3J541 (Oxysterol-binding protein OS=Lingula unguis OX=7574 GN=LOC106170170 PE=3 SV=1) HSP 1 Score: 650.973 bits (1678), Expect = 0.000e+0 Identity = 390/889 (43.87%), Postives = 508/889 (57.14%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESXXXXXXXXXXXXSPHXXXXXXXXXXXXVDMKAHDQXXXXXXXXXXXXIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHV-FNVSLPRPISQNNVKLEPKYTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWG 2743
D +KG+LYKWTNYIKGYQKRWFVL NGLLSYYRN+ E++HTCRGTINL+ + I +DS S VISN QT+HLKA SE E +W+TAL LAK AI + E+ DS+ + L +++P QN L + +L DLNT L+ K + L S L +D+ + + I V + F+ + + A +N+CS+F + A ++Q+LL E EQR+RLE MVE++AKQ LEK+A K + L++ + + + K V+ +++ DD F+DA++ +H + V+LP S + KG + RV D SQ ++ +G+ Q S S D G + V S+ K Q + T+ R RR+ I RPN ++NLWGIMKNCIG++LSKIP+PVNF+EPLSM+QRLTE+FEYS+ LD AA C DS EQL++VAAFT+S+Y+TT+ RTGKPFNPLLGET+E DR DD GWR ++EQVSHHPP A+++ E + W WQEFTMSSKFRGKYLAI P+GIAHL F KS NHYTWRKVT+TVHNIIVGKLW+DNHGEMDI NH G+ CHL Y YSYFS+E R+VTGV+ D++G T +VL G WD + AKVL + VFE+GP++ LW + P +MYNFT A+ELNE E VAPTDSRLRPDQR ME WD ANKEK +LEEKQR R+ RE E EQ S+G + ++P WF D++T H+Y+ YWE K WG
Sbjct: 11 DSYKGWLYKWTNYIKGYQKRWFVLQNGLLSYYRNQAEMAHTCRGTINLANAFIHTEDSCSFVISNGGTQTYHLKASSEVERQKWVTALELAKAKAIRMMES---DSEEDEDL--------ISQPDKDELQNTL-----------------RTLGAKLEDLNTCNDLIVKHGAA-------------------------------------LQKSLSELEQLDNSTDTATRIKSVNERATLFR-------ITSSAMINACSDFLDLAQTQGKRWQRLLQHEHEQRVRLEDMVEQIAKQQQNLEKQARKSLAAANLHSKIDTNDTEPK---VEGSEEEEDD-----FFDALDIQHTEYQVALPHKPSMH---------------------------KG--LRRV-------------------GSDVSQISLDSLGAGYQRQDYDSSES--------DAEGDNEARVIATARKQSKTKMGQPGTPVRTR-RANSLRKRRSAILERPNHTLNLWGIMKNCIGRDLSKIPMPVNFSEPLSMLQRLTEEFEYSEILDTAAACEDSCEQLAYVAAFTISAYATTSFRTGKPFNPLLGETYECDRRDDYGWRVISEQVSHHPPTAAMYAEG-RDWALWQEFTMSSKFRGKYLAITPLGIAHLRFNKSGNHYTWRKVTTTVHNIIVGKLWVDNHGEMDIVNHTNGDLCHLKYSQYSYFSRETPRKVTGVVADRNGQTNWVLTGMWDEKIEGAKVLSCTTSSKGKPVFESGPSKVLWKKNPIPPGNEKMYNFTQLAVELNEMEPGVAPTDSRLRPDQRSMENQDWDGANKEKLKLEEKQRLARKRREAEAEQAASEGREYV-PYEPAWFKKTKDQQTGNLIHMYTHEYWEAKEKQDWG 760
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: Q7QGU9 (Oxysterol-binding protein (Fragment) OS=Anopheles gambiae OX=7165 GN=AgaP_AGAP010893 PE=3 SV=4) HSP 1 Score: 624.78 bits (1610), Expect = 0.000e+0 Identity = 376/894 (42.06%), Postives = 511/894 (57.16%), Query Frame = 2
Query: 77 PDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESXXXXXXXXXXXXSPHXXXXXXXXXXXXVDMKAHDQXXXXXXXXXXXXIDHRAPSHSSIGPVPDLMHKFK---EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLPRPISQNNVKLEPKYTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSV-PSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKT--GETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
PD KG+L KWTNY+KGYQKRWFVLS G+LSYYRN+ E++HTCRGTI+L ++I DS + VISN QTFH+KA +E E W+TAL LAK AI E+ ++ D+ A N +P + +++L +E RL +L T L+ K +L RA S G DL +K K E+ F +++ A +N+CS++ A K+ K+L ER+Q+L LE+MVE+LA+Q LE+ A + S ++++ ASDD D+E FYDA E+ + + + + +N + + +++ G+S G+S R++++G S S P + A DN+ DV+ + ++Q++ P+L+ + K R RRT++ +PN +NLW I+KNCIGK+LSKIP+PVNFNEPLSM+QRLTEDFEYS+ LD AA+ D+ EQL++V AFTVSSYSTT+NRTGKPFNPLLGET+E DRTDDLGWR + EQVSHHPP A+ +CE +GW+CWQEFTM+SKFRGKY+ I+P+G AH+ F + N YTWRKVT+TVHNIIVGKLW+DNHG+M+I+ + G CHL Y YSYF+++ RRV GV+ D K+V+NGTWDS + A V N V++TG +T W+RR PP + YNFT A +LNEPE VAPTDSRLRPDQRLME G W+E+N+EK RLEE QR +RR RE E E ++G P ++P+WF +E T H+Y+G YW+ KA G W
Sbjct: 14 PDM-KGWLLKWTNYLKGYQKRWFVLSKGVLSYYRNQAEMAHTCRGTISLHGALIHTVDSCTFVISNGGTQTFHIKAANEVERQSWVTALELAKAKAIRAMESDEEEEDNTA--------------------NTIP--------SEELNLVVRELTVRLENLKTCYDLITKHGAAL------------------------------------------------QRALSELETGD--DLANKTKIVSERATLFRISSNAMINACSDYLQTAQTQGHKWSKMLQHERDQKLHLEEMVEQLARQHSHLEQAATRHRPSDHVSSATKS---------FNAATSASDDEDNE-FYDAQEE------------GGSVTQEDSSFILNIPVTTHHNHRRNSNDATGSS-------------------SEGEDGNSETQQCRSLTAGHLSLSFSPRTGISAE--NLDNM---------DVTDRISVHSSQALTPTLAN--QSKVVRKRRTRVPDKPNYPLNLWSIIKNCIGKDLSKIPMPVNFNEPLSMLQRLTEDFEYSEILDKAAQAKDTCEQLAYVTAFTVSSYSTTSNRTGKPFNPLLGETYECDRTDDLGWRCINEQVSHHPPMAAQYCEG-RGWRCWQEFTMTSKFRGKYIQIVPLGYAHVEFPATGNRYTWRKVTTTVHNIIVGKLWVDNHGDMEIFGERNAKGVKCHLKYLPYSYFTRDTQRRVKGVVMDSSNQVKWVVNGTWDSKIEIAPVTSTSGSTEN-PVYKTGNYKTAWTRRMPPPDSDRYYNFTLLACQLNEPEPGVAPTDSRLRPDQRLMEDGKWNESNQEKLRLEEGQRARRRQREAEAETAAAEGR-PYPPYEPIWFGKEKEEGTDNLVHVYNGTYWDAKAKGDW 771
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A4Y2GK20 (Oxysterol-binding protein 1 OS=Araneus ventricosus OX=182803 GN=OSBP PE=4 SV=1) HSP 1 Score: 538.11 bits (1385), Expect = 8.353e-175 Identity = 304/664 (45.78%), Postives = 410/664 (61.75%), Query Frame = 2
Query: 779 VPDLMHKFK---EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHV-FNVSLPRPISQNNVKLEPKYTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKK-----PARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
VPD ++K + E+ F + + A +N+C ++ A K+ K++ E EQRLRLE+MVE+LAKQ LE+ A + S + S HSDD++ FYDA E+ F +++P + + + +++ +++G S+ + GD RR + S+C +N + N++ + ++ +A P+ ST EK P + RR + +PN S+NLW IMKNCIGKEL+KIP+PVNFNEPLS +QRLTE++EYSD LD AA+C+DS EQ+++VAA+TVS+Y+TT+NRTGKPFNPLLGET+E DRTDD GWR L+EQVSHHPP + HCE +GW CWQEFTMSSKFRGKYL IIP+GIAHL F S NHYTWRKVT+ VHNIIVG+LW+D+HGEM+I NH T + CHL + YSYFS+E R+VTGV+TD +G K+VL GTWD+ + A+VL+ + + ET +T+W R+FP PEY +MYNFT A +LNEPEE VAPTDSR+RPDQRLME G WDEAN+ K +LEEKQR+ RR +E+E EQ ++G P + ++P+WF DE T H + G YW+ K W
Sbjct: 169 VPDAVNKIRSVNERATLFRITSNAMINACQDYLQLAQTQGRKWMKMVQHEHEQRLRLEEMVEQLAKQHSHLERAAKEAS-----SNSPGMHSDDDE------------------FYDAEEETGSDFVITIPGKVHR---RTPSGFSLQSEGQDLDGGASSDTDAEGTSLTK--------------------SGD--MIARRKKRNRGQVHSVCVTNHCEDNESDSER----------------KVSSASESPTHSTNAEKDNKSLVPVKNRRLTVPEKPNYSLNLWSIMKNCIGKELTKIPMPVNFNEPLSTLQRLTEEYEYSDLLDKAAQCSDSCEQMAYVAAYTVSAYATTSNRTGKPFNPLLGETYECDRTDDYGWRCLSEQVSHHPPMLAQHCEG-RGWICWQEFTMSSKFRGKYLQIIPLGIAHLLFPASGNHYTWRKVTTFVHNIIVGRLWVDHHGEMEIVNHHTEDKCHLRFIPYSYFSREVPRKVTGVVTDHEGNAKFVLQGTWDNKMESARVLNSHGSVKGKPLLETSTPKTIWRRQFPGPEY-EKMYNFTVLACQLNEPEEGVAPTDSRVRPDQRLMEDGAWDEANRIKVQLEEKQRQVRRKKEEEAEQAAAEGR-PYQGYEPIWFTKETDEITGNPVHKFKGEYWKCKENQDW 765 HSP 2 Score: 145.976 bits (367), Expect = 5.571e-32 Identity = 69/108 (63.89%), Postives = 83/108 (76.85%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
KG+LYKWTNY+KGYQKRWFVL NGLLSYYRN NEV+HTCRGTINL +++I DS + VISN QTFHLKA +E E +W+TAL LAK AI ++E+ D+ S P
Sbjct: 13 KGWLYKWTNYLKGYQKRWFVLYNGLLSYYRNPNEVAHTCRGTINLVSAVIHTVDSSNFVISNGGTQTFHLKASNEIERQRWVTALELAKARAIRMTESDEDEDYSLLP 120
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A1S3J6B2 (Oxysterol-binding protein OS=Lingula unguis OX=7574 GN=LOC106170170 PE=3 SV=1) HSP 1 Score: 534.258 bits (1375), Expect = 4.001e-173 Identity = 304/647 (46.99%), Postives = 395/647 (61.05%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHV-FNVSLPRPISQNNVKLEPKYTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWG 2743
E+ F + + A +N+CS+F + A ++Q+LL E EQR+RLE MVE++AKQ LEK+A K + L++ + + + K V+ +++ DD F+DA++ +H + V+LP S + KG + RV D SQ ++ +G+ Q S S D G + V S+ K Q + T+ R RR+ I RPN ++NLWGIMKNCIG++LSKIP+PVNF+EPLSM+QRLTE+FEYS+ LD AA C DS EQL++VAAFT+S+Y+TT+ RTGKPFNPLLGET+E DR DD GWR ++EQVSHHPP A+++ E + W WQEFTMSSKFRGKYLAI P+GIAHL F KS NHYTWRKVT+TVHNIIVGKLW+DNHGEMDI NH G+ CHL Y YSYFS+E R+VTGV+ D++G T +VL G WD + AKVL + VFE+GP++ LW + P +MYNFT A+ELNE E VAPTDSRLRPDQR ME WD ANKEK +LEEKQR R+ RE E EQ S+G + ++P WF D++T H+Y+ YWE K WG
Sbjct: 199 ERATLFRITSSAMINACSDFLDLAQTQGKRWQRLLQHEHEQRVRLEDMVEQIAKQQQNLEKQARKSLAAANLHSKIDTNDTEPK---VEGSEEEEDD-----FFDALDIQHTEYQVALPHKPSMH---------------------------KG--LRRV-------------------GSDVSQISLDSLGAGYQRQDYDSSES--------DAEGDNEARVIATARKQSKTKMGQPGTPVRTR-RANSLRKRRSAILERPNHTLNLWGIMKNCIGRDLSKIPMPVNFSEPLSMLQRLTEEFEYSEILDTAAACEDSCEQLAYVAAFTISAYATTSFRTGKPFNPLLGETYECDRRDDYGWRVISEQVSHHPPTAAMYAEG-RDWALWQEFTMSSKFRGKYLAITPLGIAHLRFNKSGNHYTWRKVTTTVHNIIVGKLWVDNHGEMDIVNHTNGDLCHLKYSQYSYFSRETPRKVTGVVADRNGQTNWVLTGMWDEKIEGAKVLSCTTSSKGKPVFESGPSKVLWKKNPIPPGNEKMYNFTQLAVELNEMEPGVAPTDSRLRPDQRSMENQDWDGANKEKLKLEEKQRLARKRREAEAEQAASEGREYV-PYEPAWFKKTKDQQTGNLIHMYTHEYWEAKEKQDWG 778 HSP 2 Score: 148.288 bits (373), Expect = 9.678e-33 Identity = 69/108 (63.89%), Postives = 83/108 (76.85%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSE-AVLDDSD 400
D +KG+LYKWTNYIKGYQKRWFVL NGLLSYYRN+ E++HTCRGTINL+ + I +DS S VISN QT+HLKA SE E +W+TAL LAK AI + E + +D D
Sbjct: 11 DSYKGWLYKWTNYIKGYQKRWFVLQNGLLSYYRNQAEMAHTCRGTINLANAFIHTEDSCSFVISNGGTQTYHLKASSEVERQKWVTALELAKAKAIRMMESGISEDGD 118
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A2R2MKW8 (Oxysterol-binding protein OS=Lingula unguis OX=7574 GN=LOC106170170 PE=3 SV=1) HSP 1 Score: 529.25 bits (1362), Expect = 3.666e-171 Identity = 303/647 (46.83%), Postives = 392/647 (60.59%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHV-FNVSLPRPISQNNVKLEPKYTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWG 2743
E+ F + + A +N+CS+F + A ++Q+LL E EQR+RLE MVE++AKQ LEK+A K + L++ + D + +++ DD F+DA++ +H + V+LP S + KG + RV D SQ ++ +G+ Q S S D G + V S+ K Q + T+ R RR+ I RPN ++NLWGIMKNCIG++LSKIP+PVNF+EPLSM+QRLTE+FEYS+ LD AA C DS EQL++VAAFT+S+Y+TT+ RTGKPFNPLLGET+E DR DD GWR ++EQVSHHPP A+++ E + W WQEFTMSSKFRGKYLAI P+GIAHL F KS NHYTWRKVT+TVHNIIVGKLW+DNHGEMDI NH G+ CHL Y YSYFS+E R+VTGV+ D++G T +VL G WD + AKVL + VFE+GP++ LW + P +MYNFT A+ELNE E VAPTDSRLRPDQR ME WD ANKEK +LEEKQR R+ RE E EQ S+G + ++P WF D++T H+Y+ YWE K WG
Sbjct: 199 ERATLFRITSSAMINACSDFLDLAQTQGKRWQRLLQHEHEQRVRLEDMVEQIAKQQQNLEKQARKSLAAANLHSKI----DTNDTEPKEGSEEEEDD-----FFDALDIQHTEYQVALPHKPSMH---------------------------KG--LRRV-------------------GSDVSQISLDSLGAGYQRQDYDSSES--------DAEGDNEARVIATARKQSKTKMGQPGTPVRTR-RANSLRKRRSAILERPNHTLNLWGIMKNCIGRDLSKIPMPVNFSEPLSMLQRLTEEFEYSEILDTAAACEDSCEQLAYVAAFTISAYATTSFRTGKPFNPLLGETYECDRRDDYGWRVISEQVSHHPPTAAMYAEG-RDWALWQEFTMSSKFRGKYLAITPLGIAHLRFNKSGNHYTWRKVTTTVHNIIVGKLWVDNHGEMDIVNHTNGDLCHLKYSQYSYFSRETPRKVTGVVADRNGQTNWVLTGMWDEKIEGAKVLSCTTSSKGKPVFESGPSKVLWKKNPIPPGNEKMYNFTQLAVELNEMEPGVAPTDSRLRPDQRSMENQDWDGANKEKLKLEEKQRLARKRREAEAEQAASEGREYV-PYEPAWFKKTKDQQTGNLIHMYTHEYWEAKEKQDWG 777 HSP 2 Score: 148.288 bits (373), Expect = 9.892e-33 Identity = 69/108 (63.89%), Postives = 84/108 (77.78%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEA-VLDDSD 400
D +KG+LYKWTNYIKGYQKRWFVL NGLLSYYRN+ E++HTCRGTINL+ + I +DS S VISN QT+HLKA SE E +W+TAL LAK AI + E+ + +D D
Sbjct: 11 DSYKGWLYKWTNYIKGYQKRWFVLQNGLLSYYRNQAEMAHTCRGTINLANAFIHTEDSCSFVISNGGTQTYHLKASSEVERQKWVTALELAKAKAIRMMESGISEDGD 118
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 481.871 bits (1239), Expect = 5.455e-158 Identity = 245/406 (60.34%), Postives = 296/406 (72.91%), Query Frame = 2
Query: 1541 EKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNN------QQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
E P R RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEP+SM+QRL+ED EYS+ LD A+C SLEQL +VAAFTVSSYSTT +RTGKPFNPLLGETFE DR + G+RSL EQVSHHPPAA+ H S +GW QE T++SKFRGKYL+I+P+G H F+KSNNHY+W+KVT+TVHNIIVGKLWID GE+D+ NH+TG+ CHL + YSYFS++ AR+VTGV+TDKDG YVL+GTWD + ++V+ + N + V++T A LW + PE MY FT AL LNE E+ VAPTDSR RPDQRLME G WDEAN EK+RLEEKQR RR RE+E ++ P + + +WF V DE T THIY G YWETK G W
Sbjct: 255 EVVPVRKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAWAKEHGA--PQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTW 658 HSP 2 Score: 72.7886 bits (177), Expect = 1.073e-12 Identity = 34/61 (55.74%), Postives = 44/61 (72.13%), Query Frame = 2
Query: 191 VSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISL 373
+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ +
Sbjct: 1 MGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRM 61 HSP 3 Score: 63.929 bits (154), Expect = 7.139e-10 Identity = 42/129 (32.56%), Postives = 65/129 (50.39%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLP 1159
G D + + E+ F + + A +N+C +F A ++QK L ER+QR+RLE+ +E+LAKQ LE+ + +S P D ASDD D+E F+DA ED F +++P
Sbjct: 118 GDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLERAFRGATVLPASPSSGPGKGD------------ASDDDDNE-FFDACEDVQEF-ITIP 232
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 482.641 bits (1241), Expect = 6.276e-157 Identity = 250/429 (58.28%), Postives = 304/429 (70.86%), Query Frame = 2
Query: 1478 DVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNN------QQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQG--LPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
D +T + ++ S P E P R RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEP+SM+QRL+ED EYS+ LD A+C SLEQL +VAAFTVSSYSTT +RTGKPFNPLLGETFE DR + G+RSL EQVSHHPPAA+ H S +GW QE T++SKFRGKYL+I+P+G H F+KSNNHY+W+KVT+TVHNIIVGKLWID GE+D+ NH+TG+ CHL + YSYFS++ AR+VTGV+TDKDG YVL+GTWD + ++V+ + N + V++T A LW + PE MY FT AL LNE E+ VAPTDSR RPDQRLME G WDEAN EK+RLEEKQR RR RE+E + S P + + +WF V DE T THIY G YWETK G W
Sbjct: 326 DGTTSLDEQSLASNPESPQSQEVVPVRKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAVRLASTAEEGAPQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTW 754 HSP 2 Score: 147.902 bits (372), Expect = 4.524e-36 Identity = 71/121 (58.68%), Postives = 87/121 (71.90%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSL 442
D +KG+L+KWTNYIKGYQ+RWFVLSNGLLSYYR + E+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ + +A DDS E P G L
Sbjct: 13 DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRM-QAESDDSGDECSTSPPSAGQGL 132 HSP 3 Score: 65.855 bits (159), Expect = 1.729e-10 Identity = 45/129 (34.88%), Postives = 71/129 (55.04%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLP 1159
G D + + E+ F + + A +N+C +F A ++QK L ER+QR+RLE+ +E+LAKQ LE +A + + + + S P + D K D ASDD D+E F+DA ED F +++P
Sbjct: 181 GDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLE-RAFRGATVLPASPSNP--TADSKGSGPGKGD-ASDDDDNE-FFDACEDVQEF-ITIP 303
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 478.404 bits (1230), Expect = 3.811e-155 Identity = 250/442 (56.56%), Postives = 304/442 (68.78%), Query Frame = 2
Query: 1478 DVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNN------QQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQG---------------LPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
D +T + ++ S P E P R RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEP+SM+QRL+ED EYS+ LD A+C SLEQL +VAAFTVSSYSTT +RTGKPFNPLLGETFE DR + G+RSL EQVSHHPPAA+ H S +GW QE T++SKFRGKYL+I+P+G H F+KSNNHY+W+KVT+TVHNIIVGKLWID GE+D+ NH+TG+ CHL + YSYFS++ AR+VTGV+TDKDG YVL+GTWD + ++V+ + N + V++T A LW + PE MY FT AL LNE E+ VAPTDSR RPDQRLME G WDEAN EK+RLEEKQR RR RE+E + S P + + +WF V DE T THIY G YWETK G W
Sbjct: 326 DGTTSLDEQSLASNPESPQSQEVVPVRKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAVRLASTAEEAVIEDSITDSPLKSAPQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTW 767 HSP 2 Score: 147.902 bits (372), Expect = 4.116e-36 Identity = 71/121 (58.68%), Postives = 87/121 (71.90%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSL 442
D +KG+L+KWTNYIKGYQ+RWFVLSNGLLSYYR + E+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ + +A DDS E P G L
Sbjct: 13 DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRM-QAESDDSGDECSTSPPSAGQGL 132 HSP 3 Score: 65.855 bits (159), Expect = 1.730e-10 Identity = 45/129 (34.88%), Postives = 71/129 (55.04%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLP 1159
G D + + E+ F + + A +N+C +F A ++QK L ER+QR+RLE+ +E+LAKQ LE +A + + + + S P + D K D ASDD D+E F+DA ED F +++P
Sbjct: 181 GDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLE-RAFRGATVLPASPSNP--TADSKGSGPGKGD-ASDDDDNE-FFDACEDVQEF-ITIP 303
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 471.47 bits (1212), Expect = 2.589e-152 Identity = 250/458 (54.59%), Postives = 304/458 (66.38%), Query Frame = 2
Query: 1478 DVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNN------QQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEE-------------------------------HKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
D +T + ++ S P E P R RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEP+SM+QRL+ED EYS+ LD A+C SLEQL +VAAFTVSSYSTT +RTGKPFNPLLGETFE DR + G+RSL EQVSHHPPAA+ H S +GW QE T++SKFRGKYL+I+P+G H F+KSNNHY+W+KVT+TVHNIIVGKLWID GE+D+ NH+TG+ CHL + YSYFS++ AR+VTGV+TDKDG YVL+GTWD + ++V+ + N + V++T A LW + PE MY FT AL LNE E+ VAPTDSR RPDQRLME G WDEAN EK+RLEEKQR RR RE+E + S + E + +WF V DE T THIY G YWETK G W
Sbjct: 326 DGTTSLDEQSLASNPESPQSQEVVPVRKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAVRLASTAEEAVIEDSITDSPLKTDDVEFSSDPSDSAFKSAPQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTW 783 HSP 2 Score: 147.902 bits (372), Expect = 4.511e-36 Identity = 71/121 (58.68%), Postives = 87/121 (71.90%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSL 442
D +KG+L+KWTNYIKGYQ+RWFVLSNGLLSYYR + E+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ + +A DDS E P G L
Sbjct: 13 DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRM-QAESDDSGDECSTSPPSAGQGL 132 HSP 3 Score: 65.855 bits (159), Expect = 1.779e-10 Identity = 45/129 (34.88%), Postives = 71/129 (55.04%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLP 1159
G D + + E+ F + + A +N+C +F A ++QK L ER+QR+RLE+ +E+LAKQ LE +A + + + + S P + D K D ASDD D+E F+DA ED F +++P
Sbjct: 181 GDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLE-RAFRGATVLPASPSNP--TADSKGSGPGKGD-ASDDDDNE-FFDACEDVQEF-ITIP 303
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 455.292 bits (1170), Expect = 1.165e-145 Identity = 215/358 (60.06%), Postives = 263/358 (73.46%), Query Frame = 2
Query: 1478 DVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNN------QQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEA 2533
D +T + ++ S P E P R RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEP+SM+QRL+ED EYS+ LD A+C SLEQL +VAAFTVSSYSTT +RTGKPFNPLLGETFE DR + G+RSL EQVSHHPPAA+ H S +GW QE T++SKFRGKYL+I+P+G H F+KSNNHY+W+KVT+TVHNIIVGKLWID GE+D+ NH+TG+ CHL + YSYFS++ AR+VTGV+TDKDG YVL+GTWD + ++V+ + N + V++T A LW + PE MY FT AL LNE E+ VAPTDSR RPDQRLME G WDEA
Sbjct: 326 DGTTSLDEQSLASNPESPQSQEVVPVRKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEA 683 HSP 2 Score: 147.902 bits (372), Expect = 5.419e-36 Identity = 71/121 (58.68%), Postives = 87/121 (71.90%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSL 442
D +KG+L+KWTNYIKGYQ+RWFVLSNGLLSYYR + E+ HTCRGTINL+T+ I +DS + VISN QT+HLKA SE E +W+TAL LAK A+ + +A DDS E P G L
Sbjct: 13 DTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRM-QAESDDSGDECSTSPPSAGQGL 132 HSP 3 Score: 66.2402 bits (160), Expect = 1.589e-10 Identity = 45/129 (34.88%), Postives = 71/129 (55.04%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLP 1159
G D + + E+ F + + A +N+C +F A ++QK L ER+QR+RLE+ +E+LAKQ LE +A + + + + S P + D K D ASDD D+E F+DA ED F +++P
Sbjct: 181 GDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLE-RAFRGATVLPASPSNP--TADSKGSGPGKGD-ASDDDDNE-FFDACEDVQEF-ITIP 303
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbp (oxysterol binding protein [Source:ZFIN;Acc:ZDB-GENE-090312-18]) HSP 1 Score: 466.077 bits (1198), Expect = 1.343e-151 Identity = 242/423 (57.21%), Postives = 298/423 (70.45%), Query Frame = 2
Query: 1496 ELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEH---KPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
+LK A S SL ++ K + RR +I +PN S+NLW IMKNCIGK+LSKIP+PVNFNEPLSM+QRLTED EY D LD AA+C SLEQL +VAAF+VSSYSTT RTGKPFNPLLGETFE DR ++ G+RS+ EQVSHHPPAA+ H +S +GW+ WQE T+SSKFRGKYL+IIP+G H F S NHYTW+KVT+TVHNIIVG+LWID G++DI NH TG+ C L + AYSYFS++ R+V+GV+ D +G Y+L+GTWD + AK++ + + V++T PA+ LW R PE + MY FT AL LNE EE VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE E+ +H +P+WF D T+ + +Y G YWETK W
Sbjct: 314 DLKHASSSSSLGQEMVVK--KQRRARIPDKPNYSLNLWSIMKNCIGKDLSKIPMPVNFNEPLSMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFSVSSYSTTVYRTGKPFNPLLGETFELDRLEECGYRSICEQVSHHPPAAAHHVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEFPSSGNHYTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLKFIAYSYFSRDIPRKVSGVVMDAEGNAHYILSGTWDEKMEYAKIVQSSKGSSGSEGRQKTVYQTQPAKHLWKRYPLPENSDNMYYFTELALTLNETEEGVAPTDSRLRPDQRLMENGKWDEANAEKQRLEEKQRLVRRRREAELASAAEPNGDAGRKHQSYRPMWFERKEDPFTREVSCVYRGGYWETKEKQEW 734 HSP 2 Score: 152.14 bits (383), Expect = 3.502e-38 Identity = 70/109 (64.22%), Postives = 86/109 (78.90%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSE 406
D +KG+L+KWTNYIKGYQKRWFVLSNGLLSYYR + E++HTCRGTINL+ + I +DS +IV+SN QT+HLKA SE E +W+TAL LAK AI + +A DDSD E
Sbjct: 1 DTYKGWLFKWTNYIKGYQKRWFVLSNGLLSYYRTQAEMAHTCRGTINLAGAYIDTEDSCNIVVSNGGTQTYHLKASSEVERQRWVTALELAKAKAIRMMQAESDDSDDE 109 HSP 3 Score: 55.0694 bits (131), Expect = 6.957e-8 Identity = 29/72 (40.28%), Postives = 44/72 (61.11%), Query Frame = 2
Query: 782 PDLMHKFK---EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEK 988
P+ K K E+ F + + A +N+C +F +A K+QK + EREQRLRLE+ +E+LAKQ +LE+
Sbjct: 162 PEGSEKLKAVNERATLFRITSNAMINACHDFLEQAQSQGKKWQKTVQYEREQRLRLEETLEQLAKQHNSLER 233
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 244.588 bits (623), Expect = 3.678e-68 Identity = 141/365 (38.63%), Postives = 209/365 (57.26%), Query Frame = 2
Query: 1469 VSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRT-GKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGET-CHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHF----QRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPE----ENVAPTDSRLRPDQRLMETGFWDEA 2533
+S D + + K+ QS + + + E + R SI LW I++ IGK+LSK+ +PV NEPL+++QRL E+ EYSD LD AA+ D +++ VA F VS+Y++T +R GKPFNP+LGET+E R +D G+R +AEQVSHHPP + HC+S K + WQ+ + +KF GK + IIP+G ++ K + Y W KVTS +HNI+ G+ WI+++GE+ I N K+ C +N+ SY+S E A +V G + D++G + L G W+ QR+ A +W P+ Y FT FA+ELNE + ++ PTD+R RPDQR +E G + A
Sbjct: 490 ISEDTGSRASFKSQQSNGAFTNR-EFQTGRRMHLPAPAADTSSIGLWDILRKNIGKDLSKVAMPVELNEPLNVLQRLCEEMEYSDLLDRAADTDDPAQRMVLVATFAVSTYASTISRAGGKPFNPVLGETYECIR-EDRGFRFIAEQVSHHPPISVCHCDS-KKFVLWQDVRLKNKFWGKSMEIIPVGTVNVKLLKYGDEYEWNKVTSCIHNIMGGQRWIEHYGEVIIKNKKSNVCQCKINFIKASYWSSE-ANQVQGTVMDQNGRVLHRLFGKWNEGMYCGAQRS-------------------ARCIWRPGSLPQDHELYYGFTRFAIELNELDPVLRPHLPPTDTRFRPDQRFLEEGNMESA 831
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl1a (oxysterol binding protein-like 1A [Source:ZFIN;Acc:ZDB-GENE-050208-657]) HSP 1 Score: 195.667 bits (496), Expect = 8.504e-55 Identity = 158/430 (36.74%), Postives = 219/430 (50.93%), Query Frame = 2
Query: 1583 RPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSS------KFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGV-ITDKDGVTKYVLNGTW--------------------DSHFQRAKVLHIRKDKNNQQVFETGPAE------------------TLWSRRFPPEYTSEMYNFTNFALELNEPEEN----VAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETK 2725
R N SI W ++ CIG ELSKI +PV FNEPLS +QRL E E++ + A + S+E++ VAAF VS+ ++ RTGKPFNPLLGET+E R +DLG+R ++EQVSHHPP ++ E + ++F KF GK + P GI L + YTW + VHN+IVGKLWI+ +G ++I NHK G L+++A + ++ R ++ I K V+ V+ G W S + AK++ + Q E A+ LW P +++MYNFT+FAL LNE E+ +APTD RLRPD + ME G D A +EK RLEEKQR R+ R K EE WF + T T IY+GNY++ +
Sbjct: 11 RSNFSI--WSFLRRCIGMELSKITMPVIFNEPLSFLQRLCEYMEHTYLIHKANTSSSSIERMQCVAAFAVSAVASNWERTGKPFNPLLGETYEMVR-EDLGFRLVSEQVSHHPPISAFFAEGLN-----KDFVFHGSVYPKLKFWGKSVEAEPRGIITLELPRYGEAYTWTNPSCCVHNVIVGKLWIEQYGTVEITNHKRGFKASLSFRARNITKRKSRRPLSAFRIDSKKKVS--VIYGKWTEVLWSVDPGIYEVGKKNDKKSTEKLAKLVAAESSGPSGQQAEADEADDIPTPEVPETVTVLPGSKLLWRVHPRPANSTQMYNFTSFALTLNEMEKEMEGLLAPTDCRLRPDMKAMEQGDIDLAGEEKNRLEEKQRAARKQRAKTE-----------EEWHTRWFRQDLNPHTSTADWIYAGNYFDRR 419
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 119.013 bits (297), Expect = 2.884e-28 Identity = 76/161 (47.20%), Postives = 111/161 (68.94%), Query Frame = 2
Query: 1577 TPRPNMS-INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTG-KPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEK 2053
P P+ S ++LW I++N IGK+L+K+ +PV NEPL+ +QRL E+ EYS+ L+ A++ D +++ AAF VS+Y+ T R+G KPFNP+LGET+E R +D G+R +AEQVSHHPP ++ HCES K + WQ+ +KF GK + I+P+G L K
Sbjct: 349 APCPDTSGVSLWNILRNNIGKDLAKVSMPVELNEPLNTLQRLCEELEYSELLEQASDTEDPAQRMVLAAAFAVSAYAPTYYRSGNKPFNPVLGETYECIR-EDKGFRFVAEQVSHHPPISACHCES-KTFVLWQDVRWKNKFWGKSMEILPLGTVSLNLPK 507
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: OSBPL8 (oxysterol binding protein like 8 [Source:HGNC Symbol;Acc:HGNC:16396]) HSP 1 Score: 83.5741 bits (205), Expect = 1.223e-16 Identity = 63/236 (26.69%), Postives = 111/236 (47.03%), Query Frame = 2
Query: 1604 LWGIMKNCI-GKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLD-AAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFE---FDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMS-SKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYF-SKEPARRVTGVITDKDGVTKYVLNGTWD 2290
+WG++K G +LS++ +P EP S + +L++ + ++D L AA ++ ++ V + +S + KP+NP+LGETF + + D +AEQVSHHPP ++++ + K C + SKF G L+ I G LT + Y + I+ G + ++ G++ I KTG + + +K + +++G I V L G WD
Sbjct: 295 IWGLIKQLRPGMDLSRVVLPTFVLEPRSFLDKLSDYYYHADLLSHRAALEENAYGRMKQVVQWYLSGFYKKPQGPKKPYNPILGETFRCMWYHPSTDSKTYYIAEQVSHHPPVSAIYVSNRKDGFCISATVFARSKFYGNSLSAILDGTVRLTLLERGEEYVITMPYAHCKGILYGTMTLELGGKIGIECQKTGYSASIEFKLRPLLGGNDCVNQISGKIQLGKEVL-CTLEGHWD 529
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH2 (Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002177]) HSP 1 Score: 243.432 bits (620), Expect = 6.244e-67 Identity = 157/396 (39.65%), Postives = 222/396 (56.06%), Query Frame = 2
Query: 1583 RPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNH----YTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKV-----LHIRKDKNNQQVFETGPAE-----TLWSRRFPPEYTSEMYNFTNFALELNEPEEN----VAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYW 2716
RP +S LW ++K+ +GK+++++ +PV FNEP S++QR+ ED EYS+ LD AA DS + +VAAFT SSY++TT R KPFNPLLGETFE+ R D +R EQVSHHPP ++ ES + W W E + +KF G+ + +G+ H+ ++N YTW+K +TV I++G +DNHGE+++ NH TG+ C L +KA + S A +TG + +K ++L G W+ KV L + K + GP + +W PE E +N T FA+ LN P+ + + PTD+RLRPDQR ME G +DEA EK R+EEKQR RR RE+ E+ P WF TK Y+G YW
Sbjct: 893 RPKIS--LWAVLKSMVGKDMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVAKPFNPLLGETFEYSRPDK-QYRFFTEQVSHHPPISATWTESPR-WDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGDHCKLYFKARGWRS-SGAYEITGEVYNKKKQKVWILGGHWNEAIFAKKVVKDGDLSLEKTRTAASAG-NGPTDDGTKFLIWKANDRPE---EPFNLTPFAITLNAPQPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEKFRVEEKQRAARRKREENNL-----------EYHPQWFVRDTHPITKAKYWRYTGKYW 1268 HSP 2 Score: 65.0846 bits (157), Expect = 5.245e-11 Identity = 39/108 (36.11%), Postives = 60/108 (55.56%), Query Frame = 2
Query: 71 SRPDCHKGYLYKWTNYIKGYQKRWFVLS-NGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDS----FSIVISNDSNQTFHLKAQSESETNQWL----TALHLAKDTAI 367
S+P +KG+L KWTN+ GY+ RWF+LS +G LSYY++++ V RGT+ +ST + S F ++ + LK ET +W+ +A+ AKD I
Sbjct: 287 SKPPTYKGFLKKWTNFAHGYKLRWFILSGDGNLSYYKDQSHVDRP-RGTLKVSTCRLHIDSSEKLNFELLGGITGTTRWRLKGNHPIETTRWVNAIQSAIRFAKDKEI 393
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: SWH1 (Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication [Source:SGD;Acc:S000000081]) HSP 1 Score: 236.113 bits (601), Expect = 1.364e-64 Identity = 155/393 (39.44%), Postives = 225/393 (57.25%), Query Frame = 2
Query: 1598 INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNN------HYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVL----HIRKDKNNQQVFETGPAETLWSRRF---PPEYTSEMYNFTNFALELNEPEEN----VAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETK 2725
I LW ++K+ +G++L+K+ +PV+FNEP S++QR++ED EYS LD AA DS ++ +VAAFT S Y++TTNR KPFNPLLGETFE+ RTD +R EQVSHHPP ++ ES K W + E + S F G+ A+ +G+ ++T +N Y+W+K +TV I++GK +DN G++ + NH TG+ C L+YKA+ + S A V G + +KD +VL G W+ KV + D+ TG + S+ E S +N T+FAL LN + +APTDSRLRPDQR ME G +D+A EK R+E KQR ++ RE++ EE++P WF TK+ ++G YW +
Sbjct: 798 IGLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYASTTNRVSKPFNPLLGETFEYARTDG-QYRFFTEQVSHHPPISATWTESPK-WDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSA-GAYEVRGEVFNKDDKKLWVLGGHWNDSIYGKKVTARGGELTLDRIKTANSATGGPKLDGSKFLIWKANERPSVPFNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAKKEREQKG-----------EEYRPKWFVQEEHPVTKSLYWKFNGEYWNKR 1176 HSP 2 Score: 80.1073 bits (196), Expect = 1.301e-15 Identity = 42/106 (39.62%), Postives = 63/106 (59.43%), Query Frame = 2
Query: 83 CHKGYLYKWTNYIKGYQKRWFVL-SNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDS----FSIVISNDSNQTFHLKAQSESETNQWL----TALHLAKDTAISL 373
+KGYL KWTN+ +GY+ RWF+L S+G LSYY ++ + + CRG++N+S+ + S F I+ N+ +HLK ETN+W+ A+ AKD I L
Sbjct: 283 TYKGYLKKWTNFAQGYKLRWFILSSDGKLSYYIDQADTKNACRGSLNMSSCSLHLDSSEKLKFEIIGGNNGVIRWHLKGNHPIETNRWVWAIQGAIRYAKDREILL 388
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH3 (Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding [Source:SGD;Acc:S000001115]) HSP 1 Score: 158.303 bits (399), Expect = 6.147e-40 Identity = 105/329 (31.91%), Postives = 159/329 (48.33%), Query Frame = 2
Query: 1562 RRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFS-KEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEE----NVAPTDSRLRPDQRLMETGFWDEA 2533
RR I +L ++ +GK+LS I +PV NEP+S++Q ++E FEY+ L A + D + +S A +S Y T KPFNPLL ETFE R +D+G+R ++E+VSH PP + E + W+C T S KF GK + + GI L F+ + + W + T+ + N+I G+ +++ E ++++ K G+ H+ + FS + +V+ + K L G W Q + ET+W + Y FT F LNE E N+ PTDSRLRPD R E G D+A
Sbjct: 629 RRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIR-EDMGFRLISEKVSHRPPVFAFFAEHL-DWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSK-GDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKW-----------------TQSLANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKA 937
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH7 (Oxysterol-binding protein; part of family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; OSH7 has a paralog, OSH6, that arose from the whole genome duplication [Source:SGD;Acc:S000001043]) HSP 1 Score: 74.7146 bits (182), Expect = 1.970e-14 Identity = 66/240 (27.50%), Postives = 103/240 (42.92%), Query Frame = 2
Query: 1613 IMKNCI-----GKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFE--FDRTDDLGWRSLAEQVSHHPP-AASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTF---EKSNN---HYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWD 2290
I+ N I G +LS+I +P E SM++R+T ++ D L A D L++ V A+ ++ + KP NP+LGE F +D + +AEQ SHHPP +A + + SKF G A + G+ L F + +N YT + I+ GK+ I+ M I K + +K + S + G I D DG Y ++G W+
Sbjct: 50 ILLNIISQLKPGCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDGLQRFVKVVAWYLAGWHIGPRAVKKPLNPILGEHFTAYWDLPNKQQAFYIAEQTSHHPPESAYFYMIPESNIRVDGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLSQPNVYARGILFGKMRIELGDHMVIMGPKY--QVDIEFKTKGFISGT-YDAIEGTIKDYDGKEYYQISGKWN 286
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH6 (Member of an oxysterol-binding protein family; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuolar fusion; OSH6 has a paralog, OSH7, that arose from the whole genome duplication [Source:SGD;Acc:S000001711]) HSP 1 Score: 66.6254 bits (161), Expect = 8.845e-12 Identity = 59/243 (24.28%), Postives = 103/243 (42.39%), Query Frame = 2
Query: 1589 NMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFE--FDRTDDLGWRSLAEQVSHHPP-AASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFE--KSNN----HYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWD 2290
N+ +N+ ++ G +L++I +P E SM++R+T ++ + L A D L++ +V + ++ + KP NP+LGE F +D + ++EQ SHHPP A + + S+F G A + G L F K N Y + V I+ GK+ I+ M I + K Y + + + + G + D DG Y ++G W+
Sbjct: 49 NIILNIISQLRP--GCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIELGDHMIIKSPNFQADIEFKTKGYVFGTYD---AIEGTVKDYDGNAYYEISGKWN 286
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO44125 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7RWH9]) HSP 1 Score: 485.723 bits (1249), Expect = 4.800e-159 Identity = 243/410 (59.27%), Postives = 299/410 (72.93%), Query Frame = 2
Query: 1538 VEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVF-------ETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
+++ P + RT I PRP++SINLW I+KNCIGKEL+KIP+PVNFNEPLSM+QR+TE+ EYS+ LD AA C SLEQ+ +VAAFTVSSYSTT+NRT KPFNPLLGETFE DR++D GWRSLAEQVSHHPPA++ H E K W WQEF+ +SKFRGKYL IIP GIAHL F KS NHYTWRKVT+TVHNIIVGKLWID GEMDI NH T E CHL Y AY+YF ++ R+VTGV+TD +YV++GTWD+ + AKV++++ Q +T P LW R PP +MY T+FA+ LNEPE++VAPTDSR RPDQRLME W+EAN+EK R+E++QR +RR RE+E + S G+ E + P WF + DE T H+Y G YWE K WG+
Sbjct: 318 IDRTPLKTYRTSIPPRPDISINLWSILKNCIGKELTKIPMPVNFNEPLSMLQRITEELEYSEVLDKAAACTSSLEQMCYVAAFTVSSYSTTSNRTNKPFNPLLGETFECDRSEDYGWRSLAEQVSHHPPASAFHAEH-KDWIFWQEFSATSKFRGKYLQIIPQGIAHLKFIKSGNHYTWRKVTTTVHNIIVGKLWIDQSGEMDIANHTTNENCHLKYDAYNYFGRDTPRKVTGVVTDSTKTVRYVISGTWDNKIEAAKVVYLKSPGVKAQGSSSQKGQPQTLPPVVLWKRVLPPPENEKMYAMTSFAITLNEPEDHVAPTDSRFRPDQRLMENCHWEEANQEKLRIEDQQRTRRRKREQEAAEALSDGI-FYEGYSPSWFEKIVDELTDMPMHVYKGGYWEAKEKKDWGS 725 HSP 2 Score: 141.739 bits (356), Expect = 1.076e-34 Identity = 75/147 (51.02%), Postives = 94/147 (63.95%), Query Frame = 2
Query: 77 PDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDI 517
PD +G+L KWTNYIKGYQ+RWFVLSNGLLSYYRN+ E++HTCRGTINL+ + I +D+ S VISN Q FHL+A +E E +W+TAL LAK AI + E SD E S H++NI P+ SS SD+
Sbjct: 8 PDHFRGWLLKWTNYIKGYQRRWFVLSNGLLSYYRNQAEMAHTCRGTINLAGAFIDTEDACSFVISNGGTQVFHLRASTEVERQRWVTALELAKAKAIKMLE-----SDEEEEGAS------------DHAENIKPL----SSKLSDL 133 HSP 3 Score: 53.9138 bits (128), Expect = 3.048e-7 Identity = 31/82 (37.80%), Postives = 46/82 (56.10%), Query Frame = 2
Query: 788 LMHKFK---EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLN 1024
L +K K EK F + + A +++C+EF A K+QK L ER QR+ LE+ VE L +Q LE+K +QS + G+
Sbjct: 163 LFNKLKAVNEKATLFRITSNAMISACAEFLELAQAQEKKWQKSLQYERNQRINLEETVEVLGRQHYLLERKCQRQSGTPGMG 244
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO41441 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7S4A2]) HSP 1 Score: 268.47 bits (685), Expect = 9.788e-81 Identity = 151/398 (37.94%), Postives = 235/398 (59.05%), Query Frame = 2
Query: 1556 RVRRTKI-TPRPNMSI-NLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDK--NNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENV-APTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATG 2734
R RRT + R SI +L MK +GK+++K+ +PV+FNEP+S +QRL+ED EY+D L+ A C ++L +L+ VAAF S+Y+T +R KPFNPLLGETFE+ D+ G+ +AEQVSHHPP ++LH ES W WQE+ + +KFRG++ +IP G HL F+ + +H++W+K +T+HNI+VG L++D G+M + NH T ETC +++ ++ +++ G + D +G +YV+ G+WD + I +D N+ + LW+ P+ + +MY FT F ++LN+P+ V PTD R RPD R +E G D + E+ + E+++ + K + P + K WF P D T+T ++Y G YW G
Sbjct: 38 RPRRTALPATRERSSIRSLISFMKTVVGKDMTKVTMPVHFNEPVSFLQRLSEDLEYADILNRACVCKNNLVKLAHVAAFASSTYATVLSRFWKPFNPLLGETFEYIDNDN-GFALIAEQVSHHPPISALHAES-SHWVFWQEYKLDTKFRGQFFKVIPTGHCHLKFKTNGHHFSWKKPVTTIHNILVGSLYVDQEGDMVVTNHTTKETCTVHFMPVRKV-QDNFKKLKGEVKDPEGKVRYVIEGSWDKSLE-----CIPQDTGFNDDSI-------DLWTAVARPDDSYKMYAFTRFTIQLNDPDYGVTCPTDCRNRPDIRQLELGKIDSS-----AAEKHRLEEKQRASRRERDTKGEAWTPRYDKKDRWFVPKEDPYTRTFDYVYRGGYWTNIMDG 415
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO39767 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7S940]) HSP 1 Score: 221.09 bits (562), Expect = 3.930e-64 Identity = 154/399 (38.60%), Postives = 209/399 (52.38%), Query Frame = 2
Query: 1598 INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTM------SSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQ--RAKVLHIRKD-KNNQQVFETGPAE------------TLWSRRFPPEYTSEMYNFTNFALELNE----PEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWE 2719
++W ++K CIGK+LS+I +PV FNEPL+ +QR+TE EYS+ L AA D +L + GKPFNPLLGET+E R G+R +AEQVSHHPP +L CES +F KF GK + + P G+ L F K N YTW V S VHNIIVG+LWI+ +G+++I + +G+ +++K +F KE + + +D +Y L G W R++ RK K +Q FE TLW+ P ++ EMYNFT+FA++LNE +E + PTDSRLRPD R +E G D A EK RLEEKQR RR R+K +E P WF + T +YSG YW+
Sbjct: 7 FSVWTVLKQCIGKDLSRITMPVIFNEPLTFLQRITEYMEYSELLHTAASQDDPTRRL----------------QVGKPFNPLLGETYELVRP---GFRLVAEQVSHHPPITALQCES-------DDFIFHVTVQPKLKFWGKGVEVQPKGMVTLKFPKHNEVYTWNNVNSCVHNIIVGQLWIEQYGQIEISSLSSGDRATIHFKPAGWFGKELNKVEATIHCAQDKKKRYTLKGDWTDKITCYRSETHVTRKQSKRGKQDFEIASTSSSETSLELHSPVTLWTCSHRPPHSKEMYNFTSFAMQLNELLPRDKETLPPTDSRLRPDCRALENGDLDRATAEKIRLEEKQRAARRERQKSD-----------QEWAPRWFKEEMNPYTGQMDWLYSGGYWD 368
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO35914 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7SK18]) HSP 1 Score: 84.3445 bits (207), Expect = 1.045e-16 Identity = 65/243 (26.75%), Postives = 114/243 (46.91%), Query Frame = 2
Query: 1589 NMSINLWGIMKNCI-GKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRS--LAEQVSHHPPAASLHCESIK-GWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKE-PARRVTG-VITDKDGVTKYVLNGTWDSHF 2299
N SI LW ++K G +LS++ +P EP S + +L++ + ++D L AA + ++ V + +S + KP+NP++GE F G R+ ++EQVSHHPP ++ + + + G+ SKF G + I G A L + YT + I++G L ++ G + I KTG + +K ++ K + + G +I K+ + K + G WD
Sbjct: 240 NKSI-LWALLKQVKPGMDLSRVTLPTFILEPRSFLDKLSDFYYHTDILSRAACEENPYSRMKEVIRWYLSGFYKKPKGLKKPYNPIIGEMFRCYWQHPQGSRTFFVSEQVSHHPPVSAFYVSNRQDGFVINGAILAKSKFYGNSSSAILDGAATLALLRFGEEYTMTMPYAHCKGILIGTLTMELGGTVTINCEKTGYKAEIEFKLKPFWKKSGESNYIAGKIIMGKETLCK--IEGKWDGEI 479
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO37291 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG84]) HSP 1 Score: 77.411 bits (189), Expect = 1.181e-14 Identity = 36/91 (39.56%), Postives = 55/91 (60.44%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIR--KQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAK 355
+G L+KWTNY+ G+Q R+FVL G+LSYY+++ EV RG+I +S I D+ I + Q +L+A + +E QW+ A+ AK
Sbjct: 2 EGTLWKWTNYLSGWQPRYFVLEVGVLSYYKSQEEVGLGSRGSIKMSCCEISVHPTDTVRIDLRIPPEQYIYLRAATPAERQQWVVAMGTAK 92
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: si:ch211-106a19.1 (oxysterol-binding protein 2 [Source:NCBI gene;Acc:101175572]) HSP 1 Score: 454.521 bits (1168), Expect = 3.235e-148 Identity = 235/430 (54.65%), Postives = 295/430 (68.60%), Query Frame = 2
Query: 1487 TFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLP-PI------EEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
T + +++Q ++ + P++ RRT++ +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA C SLEQ+ VAAF+VSSYSTT +RT KPFNPLLGET+E DR ++ G+RSL EQVSHHPPAA+ H S +GW WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G+++I NH+T E C L + YSYFS++ R+VTGV+ D G Y+L+GTWD + AK+L + + V++T + LW + PE MY F++ AL LNEPEE VA TDSRLRPDQRLME G WDEAN EK+RLEEKQR RR R +G P P+ E ++P+WF D T T+ +Y G YWETK + W
Sbjct: 179 TVTASESSQGTAAVKWRSAPAPSK-RRTRVPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCESSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVISQRGWTLWQEITIASKFRGKYLSIMPLGTIHLQFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIVNHRTKEACQLKFSPYSYFSRDVPRKVTGVVADSSGQAHYILSGTWDDKMESAKILQSSRGGSGSEGKQKTVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEPEEGVAVTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRAVRRRR---------EGCPGPLCCASEYEGYQPLWFHQRRDSLTGETSFVYKGGYWETKESQDW 598 HSP 2 Score: 60.077 bits (144), Expect = 8.886e-9 Identity = 37/113 (32.74%), Postives = 60/113 (53.10%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F + A ++Q+ L EREQR LE+ +E+LAKQ +LE+ E+ L +S P K + ASD+ +D ++DA+ED F
Sbjct: 74 ERATLFRITSNAMINACRDFLDLAETHSRRWQRALQYEREQRTHLEETIEQLAKQHNSLER---AWREAPTLASSSPSAPTTNKG------EPASDEDEDTEYFDAMEDSPAF 177
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: si:ch211-106a19.1 (oxysterol-binding protein 2 [Source:NCBI gene;Acc:101175572]) HSP 1 Score: 458.373 bits (1178), Expect = 3.524e-148 Identity = 234/405 (57.78%), Postives = 286/405 (70.62%), Query Frame = 2
Query: 1541 EKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
E +P R RRT++ +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA C SLEQ+ VAAF+VSSYSTT +RT KPFNPLLGET+E DR ++ G+RSL EQVSHHPPAA+ H S +GW WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G+++I NH+T E C L + YSYFS++ R+VTGV+ D G Y+L+GTWD + AK+L + + V++T + LW + PE MY F++ AL LNEPEE VA TDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE E + + E ++P+WF D T T+ +Y G YWETK + W
Sbjct: 310 ELQPRRERRTRVPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCESSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVISQRGWTLWQEITIASKFRGKYLSIMPLGTIHLQFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIVNHRTKEACQLKFSPYSYFSRDVPRKVTGVVADSSGQAHYILSGTWDDKMESAKILQSSRGGSGSEGKQKTVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEPEEGVAVTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRAVRRRREAEASEALDE---EYEGYQPLWFHQRRDSLTGETSFVYKGGYWETKESQDW 711 HSP 2 Score: 132.109 bits (331), Expect = 3.306e-31 Identity = 63/111 (56.76%), Postives = 85/111 (76.58%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
D +KG+L+KWTNY+KGYQ+RWFVLSNGLLSYYR + E++HTCRGTINL+T+ I +D+ +IV+S+ +T+HLKA +E E +W+TAL LAK AI + + D S E P
Sbjct: 16 DTYKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLATAHIDTEDACNIVLSS-GGRTYHLKASTEVERQRWVTALELAKAKAIRM---MNDQSGDEEP 122 HSP 3 Score: 62.3882 bits (150), Expect = 2.018e-9 Identity = 37/113 (32.74%), Postives = 61/113 (53.98%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F + A ++Q+ L EREQR LE+ +E+LAKQ +LE+ E+ L +S P N ++ASD+ +D ++DA+ED F
Sbjct: 184 ERATLFRITSNAMINACRDFLDLAETHSRRWQRALQYEREQRTHLEETIEQLAKQHNSLER---AWREAPTLASSSPSERS--------NKEEASDEDEDTEYFDAMEDSPAF 285
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: si:ch211-106a19.1 (oxysterol-binding protein 2 [Source:NCBI gene;Acc:101175572]) HSP 1 Score: 457.988 bits (1177), Expect = 7.419e-148 Identity = 235/412 (57.04%), Postives = 287/412 (69.66%), Query Frame = 2
Query: 1541 EKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLH-----IRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQG-------LPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
E +P R RRT++ +PN S+NLW IMKNCIGKELSKIP+PVNFNEPLSM+QRLTED EY + LD AA C SLEQ+ VAAF+VSSYSTT +RT KPFNPLLGET+E DR ++ G+RSL EQVSHHPPAA+ H S +GW WQE T++SKFRGKYL+I+P+G HL F S NHY WRKVTSTVHNIIVGKLWID G+++I NH+T E C L + YSYFS++ R+VTGV+ D G Y+L+GTWD + AK+L + + V++T + LW + PE MY F++ AL LNEPEE VA TDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE E + +G E ++P+WF D T T+ +Y G YWETK + W
Sbjct: 321 ELQPRRERRTRVPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCESSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVISQRGWTLWQEITIASKFRGKYLSIMPLGTIHLQFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIVNHRTKEACQLKFSPYSYFSRDVPRKVTGVVADSSGQAHYILSGTWDDKMESAKILQSSRGGSGSEGKQKTVYQTLSPKLLWKKYPLPENAENMYYFSSLALTLNEPEEGVAVTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRAVRRRREAEASEALDEGNTCASSAGREYEGYQPLWFHQRRDSLTGETSFVYKGGYWETKESQDW 732 HSP 2 Score: 132.88 bits (333), Expect = 2.571e-31 Identity = 63/111 (56.76%), Postives = 85/111 (76.58%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAP 412
D +KG+L+KWTNY+KGYQ+RWFVLSNGLLSYYR + E++HTCRGTINL+T+ I +D+ +IV+S+ +T+HLKA +E E +W+TAL LAK AI + + D S E P
Sbjct: 21 DTYKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLATAHIDTEDACNIVLSS-GGRTYHLKASTEVERQRWVTALELAKAKAIRM---MNDQSGDEEP 127 HSP 3 Score: 64.3142 bits (155), Expect = 5.887e-10 Identity = 39/113 (34.51%), Postives = 63/113 (55.75%), Query Frame = 2
Query: 806 EKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVF 1144
E+ F + + A +N+C +F + A ++Q+ L EREQR LE+ +E+LAKQ +LE+ E+ L +S P S N N ++ASD+ +D ++DA+ED F
Sbjct: 189 ERATLFRITSNAMINACRDFLDLAETHSRRWQRALQYEREQRTHLEETIEQLAKQHNSLER---AWREAPTLASSSP--SAPTTNKGESNKEEASDEDEDTEYFDAMEDSPAF 296
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: ENSORLT00000007524.2 (oxysterol-binding protein 1 [Source:NCBI gene;Acc:101155887]) HSP 1 Score: 443.736 bits (1140), Expect = 5.445e-142 Identity = 238/403 (59.06%), Postives = 292/403 (72.46%), Query Frame = 2
Query: 1550 PARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNN------QQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
P + RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEP+SM+QRL+ED EY + LD AA+ +SLEQ+ +VAAF VS+YSTT RTGKPFNPLLGET+E DR + G+RSL EQVSHHPPAA+ H S +GW QE T++SKFRGKYL+I+P+G H FEKSNNHYTW+KVT+TVHNIIVGKLWID GE+D+ NH TG+ CHL + YSYFS++ AR+VTGV+ DK G YVL+GTWD + ++V+ + N + V++T A+ LW R P+ MY FT AL LNEPE+ VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE+E ++S +P E +K WF D+ T H+Y G YWE K G W
Sbjct: 355 PLKKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYHELLDKAAKSHNSLEQMCYVAAFCVSAYSTTVYRTGKPFNPLLGETYELDRQRESGYRSLCEQVSHHPPAAAHHAISDRGWTLRQEITVASKFRGKYLSIMPLGTIHAIFEKSNNHYTWKKVTTTVHNIIVGKLWIDQSGEIDVVNHTTGDRCHLKFAPYSYFSRDVARKVTGVVMDKTGKAHYVLSGTWDEKMEFSRVMQSSRGGENGTEGRQKTVYQTLKAKELWRRNPLPDGAETMYYFTALALTLNEPEDGVAPTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRTARREREREALNQRSSSVPH-ENYKARWFEHTEDKITGEAVHVYKGGYWEAKDQGKW 756 HSP 2 Score: 127.102 bits (318), Expect = 1.849e-29 Identity = 63/118 (53.39%), Postives = 82/118 (69.49%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLG 433
D +KG+++KWTNYIKGYQ+RWFVLSNGLLSYYR + E+ HTCRGTINL+T+ I D+ + +I+N QT+HLKA E E +W+TAL LAK A + D D +P +P G
Sbjct: 40 DTYKGWVFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATATITVDDACNFMITNGGAQTYHLKASCEVERQKWITALELAKAKAARMQAESDDSGDDFSPSAAPGQG 157 HSP 3 Score: 66.2402 bits (160), Expect = 1.426e-10 Identity = 40/129 (31.01%), Postives = 70/129 (54.26%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLP 1159
G + + + E+ F + + A +N+C +F + A ++QK L EREQR+RLE+ +E+LAKQ LE+ +++ S D K++ + SDD D+E F+DA+E+ F +++P
Sbjct: 207 GEAGEKIRQVTERATLFRITSNAMINACRDFLSMAQTHSKRWQKALQAEREQRVRLEETLEQLAKQHNHLERAFRGAAQA--------NASADSKSISGPGKGEVSDDDDNE-FFDAMEEAPEF-ITVP 325
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: ENSORLT00000029679.1 (oxysterol-binding protein 1 [Source:NCBI gene;Acc:101155887]) HSP 1 Score: 441.425 bits (1134), Expect = 7.397e-141 Identity = 239/408 (58.58%), Postives = 294/408 (72.06%), Query Frame = 2
Query: 1550 PARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNN------QQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXS-----QGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 2740
P + RRT+I +PN S+NLW IMKNCIGKELSKIP+PVNFNEP+SM+QRL+ED EY + LD AA+ +SLEQ+ +VAAF VS+YSTT RTGKPFNPLLGET+E DR + G+RSL EQVSHHPPAA+ H S +GW QE T++SKFRGKYL+I+P+G H FEKSNNHYTW+KVT+TVHNIIVGKLWID GE+D+ NH TG+ CHL + YSYFS++ AR+VTGV+ DK G YVL+GTWD + ++V+ + N + V++T A+ LW R P+ MY FT AL LNEPE+ VAPTDSRLRPDQRLME G WDEAN EK+RLEEKQR RR RE+E ++S +G+P E +K WF D+ T H+Y G YWE K G W
Sbjct: 371 PLKKRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYHELLDKAAKSHNSLEQMCYVAAFCVSAYSTTVYRTGKPFNPLLGETYELDRQRESGYRSLCEQVSHHPPAAAHHAISDRGWTLRQEITVASKFRGKYLSIMPLGTIHAIFEKSNNHYTWKKVTTTVHNIIVGKLWIDQSGEIDVVNHTTGDRCHLKFAPYSYFSRDVARKVTGVVMDKTGKAHYVLSGTWDEKMEFSRVMQSSRGGENGTEGRQKTVYQTLKAKELWRRNPLPDGAETMYYFTALALTLNEPEDGVAPTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRTARREREREALNQRSSSTSEEGVPH-ENYKARWFEHTEDKITGEAVHVYKGGYWEAKDQGKW 777 HSP 2 Score: 127.102 bits (318), Expect = 1.854e-29 Identity = 63/118 (53.39%), Postives = 82/118 (69.49%), Query Frame = 2
Query: 80 DCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLG 433
D +KG+++KWTNYIKGYQ+RWFVLSNGLLSYYR + E+ HTCRGTINL+T+ I D+ + +I+N QT+HLKA E E +W+TAL LAK A + D D +P +P G
Sbjct: 14 DTYKGWVFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATATITVDDACNFMITNGGAQTYHLKASCEVERQKWITALELAKAKAARMQAESDDSGDDFSPSAAPGQG 131 HSP 3 Score: 54.6842 bits (130), Expect = 4.539e-7 Identity = 26/72 (36.11%), Postives = 43/72 (59.72%), Query Frame = 2
Query: 773 GPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEK 988
G + + + E+ F + + A +N+C +F + A ++QK L EREQR+RLE+ +E+LAKQ LE+
Sbjct: 181 GEAGEKIRQVTERATLFRITSNAMINACRDFLSMAQTHSKRWQKALQAEREQRVRLEETLEQLAKQHNHLER 252
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000023068.1 (SMESG000023068.1) HSP 1 Score: 1660.2 bits (4298), Expect = 0.000e+0 Identity = 892/892 (100.00%), Postives = 892/892 (100.00%), Query Frame = 2
Query: 71 SRPDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESXXXXXXXXXXXXSPHXXXXXXXXXXXXVDMKAHDQXXXXXXXXXXXXIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLPRPISQNNVKLEPKYTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
SRPDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESLLNVLKDVNKLNSPHIISNYSINSDSSVDMKAHDQSSLNSHSSVLLNIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLPRPISQNNVKLEPKYTINEYESCSSDSEYEKDNSKGNSIARVIVRSTENKSKSNHKNKINNIGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEANKEKERLEEKQREKRRNREKEIEQRKSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT
Sbjct: 4 SRPDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESLLNVLKDVNKLNSPHIISNYSINSDSSVDMKAHDQSSLNSHSSVLLNIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLPRPISQNNVKLEPKYTINEYESCSSDSEYEKDNSKGNSIARVIVRSTENKSKSNHKNKINNIGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEANKEKERLEEKQREKRRNREKEIEQRKSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 895
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000023068.1 (SMESG000023068.1) HSP 1 Score: 1651.34 bits (4275), Expect = 0.000e+0 Identity = 890/892 (99.78%), Postives = 890/892 (99.78%), Query Frame = 2
Query: 71 SRPDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESXXXXXXXXXXXXSPHXXXXXXXXXXXXVDMKAHDQXXXXXXXXXXXXIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLPRPISQNNVKLEPKYTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 2746
SRPDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEA DDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESLLNVLKDVNKLNSPHIISNYSINSDSSVDMKAHDQSSLNSHSSVLLNIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLPRPISQNNVKLEPKYTINEYESCSSDSEYEKDNSKGNSIARVIVRSTENKSKSNHKNKINNIGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEANKEKERLEEKQREKRRNREKEIEQRKSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT
Sbjct: 4 SRPDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEA--DDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESLLNVLKDVNKLNSPHIISNYSINSDSSVDMKAHDQSSLNSHSSVLLNIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIEDEHVFNVSLPRPISQNNVKLEPKYTINEYESCSSDSEYEKDNSKGNSIARVIVRSTENKSKSNHKNKINNIGDSSQFHRRTVSSGFPSQSLCPSNSLKANKNQCDNLGKDLYNVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEANKEKERLEEKQREKRRNREKEIEQRKSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWGT 893
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000008795.1 (SMESG000008795.1) HSP 1 Score: 491.5 bits (1264), Expect = 7.955e-160 Identity = 288/668 (43.11%), Postives = 392/668 (58.68%), Query Frame = 2
Query: 770 IGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIE-DEHVFNVSLPRPISQNNVKLEPK---YTINXXXXXXXXXXXXKDNSKGNSIARVIVRSTEXXXXXXXXXXXXXXGDSSQFHRRTVSSGFPSQSLCPSNSLKANKN-QCDNLGKDLY----NVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAWG 2743
+G + + KE+ F V+ + + SC+ +A T K++K++++EREQR R+E MVE+LAKQ LE + S SV L N+ A +D DE FYDA E E VFNV+LP P V L + ++ + DN G + +R + IGDSS VS+ Q L + + A +N Q N K + N+ ++ S ++ + S + + R RRT+I P+PN+++NLW ++KNCIGK+LSKIP+PVNF+EP+SM+QRL EDFEYS LD AA C + +EQ+S+VAAFTVSSY+ T R KPFNPLLGET+E DRTDD GWR AEQ+ HHPP+ ++HCES W CW +F+MS+KFRGKY+ I P+G HL F++S HY W ++ T+HNIIVG++WIDNHGEMDI N T + CHL+YK YS FS + +RVTG ITDK VLNGTWD + V+ + + T + L +R+P P + Y F++FA+ LNE EE++APTDSR RPDQ+LME G WDEANKEK RLEE+QR +R K ++ + E+KP+WF PV D E K+ T+ ++G YWE KA W
Sbjct: 171 VGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQI---SSSVQNQLKL--------NINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCSELSLEYESDVEDELSDLSDNDSGLNCSR-------------NHTDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQNNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVQGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEF-----VYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWS 808 HSP 2 Score: 130.954 bits (328), Expect = 8.526e-31 Identity = 69/129 (53.49%), Postives = 88/129 (68.22%), Query Frame = 2
Query: 89 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNI 475
KGYLYKWTNY+KGYQKRWFVL NGLLSYYRN++E++ CRGTIN+ + I DS S VIS+ QTFHLK+Q+ESE +W +AL A+ A L + D++DSE L S L N + H ++I
Sbjct: 16 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSALLAAQKKAQDLLKGC-DNNDSE--LDSNELVNGFILKLNGHLEDI 141
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000046022.1 (SMESG000046022.1) HSP 1 Score: 217.624 bits (553), Expect = 1.352e-58 Identity = 145/400 (36.25%), Postives = 219/400 (54.75%), Query Frame = 2
Query: 1562 RRTKI-TPRPNMS-INLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTG-KPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPA-----RRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFPPEYTSEMYNFTNFALELNEPEENVAP----TDSRLRPDQRLMETGFWDEAXXXXXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHKPVWFAPVFDEETKTTTHIYSGNYWETK 2725
RR K+ +P++S +L ++ IG++LSK+ +PV NEPLS++Q L E+ EYSD LDAAA+ +DSLE+++++AAF VS+Y++T R G KPFNP++GET+E+ R D GW+ +AEQVSHHPP + +CES + W WQEF + +KF GK + IP G + +K N W KVT+ ++NI +I+++G+M+ T +LN A F K + VTG I+ D K L G W + ++ A +W P+ + Y FT FA++LN + ++A TDSR RPDQR +E G EA EK ++EE QR + ++ KP+WF E +K+ ++ ++ YW K
Sbjct: 502 RRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCES-ENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNF-------TSNLNSSAKITFHKSNSWVHQKFEVTGTISCPDS-RKSQLFGKW-----------------TEGIYVGDNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLITEAEAEKTKIEELQRIALAKVKGDV------------NWKPLWFKK--HESSKSESYEFTNEYWSAK 860
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000065901.1 (SMESG000065901.1) HSP 1 Score: 200.29 bits (508), Expect = 2.045e-55 Identity = 137/430 (31.86%), Postives = 210/430 (48.84%), Query Frame = 2
Query: 1580 PRP---NMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYV---LNGTW--------------DSHFQRAKVLHIRKDKNNQQVF------------ETGPAET-------LWSRRFPPEYTSEMYNFTNFALELNEPEENVA----PTDSRLRPDQRLMETGFWDEAXXX------XXXXXXXXXXXXXXXXXXXXXXXSQGLPPIEEHK--PVWFAPVFDEETKTTTHIYSGNYW 2716
P+P ++ ++W +K CIGKELSKI +P+ FNEP+S +QRLTE EYS+ LD A D ++++ + AF VS ++ R GKPFNPLLGET+E R + ++ ++EQ+ HHPP ++ H ES +K + F GK + I P G L N YTW+ V TVHN+I+GK+WI++ G M I NH L + + +F K RV G I +++V + G W DS + V + +N+++ + P + +W + P+ ++ YNFT+F + LN+ ++ + PTDSR R D R ME G DEA K+R + + +++ + S + I K PVWFA + T ++G YW
Sbjct: 32 PKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAEIDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN---FKYVSEQICHHPPVSAFHVES-PTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKN-MHRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIENDEKGDNNNNDIDDPLPQDNTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALKSSNSKKNMNKSSSSHEITDIRNQKEGPVWFAEKLNSYTNKMEWQFTGEYW 456 The following BLAST results are available for this feature:
BLAST of Oxysterol-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Oxysterol-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031216 ID=SMED30031216|Name=Oxysterol-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2977bpback to top protein sequence of SMED30031216-orf-1 >SMED30031216-orf-1 ID=SMED30031216-orf-1|Name=SMED30031216-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=902bp MNNSRPDCHKGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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