Peroxidasin

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP--CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQD  V  G  + F C+ +      + W    +  + +   L   +  L I  V    +G Y C A N  GS    A L + P   P     P+  + E G+ V+  C + G P P ITW     + V++   GK+ +     +  N       GRY C A +  GSA VS V+++               +P  ++  +  +   I +A + ++ A   T   L D +R RS +D+ +LFR P     +E A+A +++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG NTP G    +LY+G++ P  RLVS+ L+    +TPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND PCF ++ PP D R +    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA  +RDL    G LR G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IYYE+RKIVGA +QHITY  WLP +LG  G++ LG+Y GY+  +++ I + FATAA RFGHTL+NP+LYRLDENF+ I + +LPLHKAFF+P R++ +GGIDP+LRGLF +  K     Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+  Y+ +R +C +  A TF+D   EI + EIREK++++YG   N+DLF   V+E  V G  +GPTL CLL  QFKRLRDGDR WYE+   F PAQL+QIKQ +LARILCDN+DNI+RVQ +VF +A+    +  C  IPR++L  W++C +  R
Sbjct:  423 ATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW---NKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV--------------NVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFD-SRPRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYH-----YNDLVSPQYLNLIANLSGCTAHRRVNNCSD-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQDCCEDCR 1320          

Query:  235 GQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSL---------PG---------------NSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQW----LFIKEVHEFHEGIYICTASNNKGSI-SASAKLK-IAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            G  C  +C C   TV C     + +P +   + + L L         PG               N I +I +  F++ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L    F       +L    N     +P +   L ++KRL L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +   EL C          P+    PQDA V  G+ + F C+ E   + ++ W    N+ +  +    N      L I+   E  +GIY C A N  G + +    L+      +P  V  P +     G  V   C A G+P P I+  W + ++  L  + +  I     L I+N+ + +  G Y C A++   S   +A I +
Sbjct:   33 GAGCPSRCLCFRTTVRCMHLLLEAVPAVA-PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCER--------PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRIS--WTRGDRTPLPVDPRVNITPSGGLYIQNVVQGD-SGEYACSATNNIDSVHATAFIIV 429          

Query:  817 PKFIERPQDAYVAVGDKIRFACQVENINETKVEWH-------FQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL--IRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYE-ETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTP--IGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPR-VQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVG-PVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKEC 3519
            P+F   P+D  V     + + C+ +      + W         +   T  +S   R     I    +  +G Y C A ++ G    S +L + P       + P   S E G  +  SC A G P P ITW       V++   GK+ V     +         +GRY C A +  G A  +  +T+  I+ +   +   ESS                I DA  +++ A   T   L    +  + SD+ + F  P     +E+A+A +++E  L     ++RE +VK  LT   E +   +  L++P  L++I+ LSGC       +CS + CFH KYR+ DG CNNL  P  G+AL+ F RL++P Y +GI  P  +G   G        P  RLV++   RA  +TPD + + M+M WG FL+HDLD T    S +RFSDG  C+  C ND PCFP+ T   DPR    PC+ F+RS   C SG+ S  +  ++ REQ+NQ T+++DGSNVY S   E+  LRD +   G L+ G P  PS K LLPF+     +C     ++  PCF AGDHR NE+L L  MHT+W REHNR++ EL  LN HW G+ +Y E+RKIVGA +QHITY+ WLP VLG  G + L  Y GYN  V++ I + FATAA RFGHTLINPILYRL+     I EG+LP HKA F+P R++++GGIDP+LRGLF + +K      +++ EL ++LF+ A+  A+D  A  IQRGRDHG+  Y  +R FC +   + F+D   EI  SEIR+K+R++YG PG++DL+   ++E  + G  VGPTL CL + QF+RLRDGDRFWYE+   F PAQL+Q+KQ +L+R+LCDN D+I +VQ +VF  A+   ++++CS IP+++L  W++C
Sbjct:  419 PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLR-----IDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITW---NKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQAGDDFVESS----------------ILDAVQRVDSAINSTRRHLFS-QKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQ----LIRE-RVKQGLTVDLEGKEFRYNDLVSPRSLSLIANLSGCTARRPLPNCSNR-CFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQ---PLPPPRLVATVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQES--PCFLAGDHRANEHLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDC 1298          

Query:  235 GQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXX-----------------------ANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEW-HFQF-----NDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSI-SASAKLKIAP-NQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            G  C  +C C + TV C       IP++  ++ T L L  N I +I  + FK+ K+L  + L+ N I  +  NA  G   L  LYL  N I  L +Q F        L                           NN+L  +P  S   L ++KRL L  N L C C+L +    L+     G     + C+ P  +  + +  V   E    S       P+    PQD  V  G+ + F C+ E   + ++ W H        +DT  N   + +  L I+   E  +G+Y C A N+ G   + SA L+ +    KP  V  P       G+     C A G+P P IT  W + N + L+   +++   + L ++NIT+ +  GR+ C+A++  G+ + +A I +
Sbjct:   21 GLPCPSRCLCFKSTVRCMHLMLDHIPQV-PQQTTVLDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQS-------PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLN--VFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLIT--WTRDNGLELDGS-RHVATSSGLYLQNITQRD-HGRFTCHANNSHGTVQAAANIIV 415          

Query:  817 PKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSL-------YWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKI-APNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            P F+ +PQD  V +G      C         + W      T  N L          +  L+++ + +   G + C A+N+ G++ A+A + + AP Q  + V     +  E+ + VE+ C A G P P I  +W K+   +L  EG++ V  +  +  +      +G+Y C A S  G  KVS  +T+
Sbjct:  330 PSFVIQPQDTEVLIGTSTTLECMATGHPHPLITW------TRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQ--FTVTPKDQVVLEEHA-VEWLCEADGNPPPVI--VWTKTGG-QLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTV 505          

Query: 1825 NNLINPRRGSALSPFYRLMKPEYENGINTP--IGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPR-VQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVG-PVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKEC 3519
            NNL  P  G+AL+ F RL++P Y +GI  P  +G   G        P  RLV++   RA  +TPD + + M+M WG FL+HDLD T    S +RFSDG  C+  C ND PCFP+ T   DPR    PC+ F+RS   C SG+ S  +  ++ REQ+NQ T+++DGSNVY S   E+  LRD +   G L+ G P  PS K LLPF+     +C     +   PCF AGDHR NE+L L  MHT+W REHNR++ EL  LN HW G+ +Y E+RKIVGA +QHITY+ WLP VLG  G + L  Y GYN  V++ I + FATAA RFGHTLINPILYRL+     I EG+LP HKA F+P R++++GGIDP+LRGLF + +K      +++ EL ++LF+ A+  A+D  A  IQRGRDHG+  Y  +R FC +   + F+D   EI  SEIR+K+R++YG PG++DL+   ++E  + G  VGPTL CL + QF+RLRDGDRFWYE+   F PAQL+Q+KQ +L+R+LCDN D+I +VQ +VF  A+   ++++CS IP+++L  W++C
Sbjct:    1 NNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQ---PLPPPRLVATVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQ--EQESPCFLAGDHRANEHLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDC 564          

Query: 1390 ESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRS--DIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLR--AHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV--QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKR-LGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFE-TIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWK 3513
            E +   S   ++   L + I +A+  ++ A+  T + ++   R  S S  D+ S F+QP  A   + +A+D     L    G+L E      L        + T +LT  QL ++SQ SGC    +   CS       KYR+I G+CNN   P  G++     R +  EYE+G++ P GWT  +  +G+  P  R VS++++R    ++T D   + M MQWGQF+DHDLDF+P   +   F+ G+ C  TC    PCFPI  PP DPR+  QR CI F RS  +C   ++ +       R Q+N +TSF+D S VY S+   +  LR+ T   G L +      N R LLPF+      C +    A +PCF AGD R+ E   L  MHT++MREHNRL+ ELR LN  WNGDK+Y E+RKI+GAM+Q ITY  +LP+VLG    +R LG Y GY   VD  +++VF T A RFGHT++ P ++RLD  +  + P  ++PL  AFFA  R++ +GGIDPILRGL A  +K  + D ++  EL ++LF     + LDL ALN+QR RDHGL  YN+WR FCG+ +       S  + + ++  K   +YG P N+D++ GA+ E  + G  VGP L+CL  +QF+R RDGDRFW++    F   Q   + +++L+RI+CDN+  I+ V R++F        F++CS IPRLNL  W+
Sbjct:   21 EGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVAL----GLLEEK-----LQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERCSD------KYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV-------RNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALSRISLSRIICDNT-GITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWR 713          

Query: 1303 CYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQ--SLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLR--AHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV--QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKR-LGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETI-PEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKS-KLEFIDCSNIPRLNLIPWKE 3516
            C+A  L+   K+   +  + +        E +      ++    +   +++A+  ++ A+K+  E ++   R  S S ++  S F+QP  A     +A+D     LD L   LR         + +    + T +LTP QL ++S+ SGC      + C +Q     KYR+I G CNN  +P  G++   F R +  EYE+G + P GWT G   +G+    AR VS+ ++R    ++TPD   S M MQWGQ LDHDLDFTP  A+ + F  G+ C  +CV   PCFP+  PP DPR+  Q  CI F RS   C     +I       R Q+N +TSF+D S VY S+   A  LR+++   G L V      N R LLPF+      C +    A +PCF AGD R++E   L  MHT+ +REHNRL+ EL+ LN  W+G+++Y E+RKIVGAM+Q ITY  +LP+VLG   +++ L  Y  YND VD  I++VF T A R+GHTLI P ++RLD  ++ + P   +PL + FFA  RV+ +GGIDPILRGL A  +K  + +Q+   E+ E+LF     + LDL ALN+QR RDHGL  YN+WR FCG+ + ET       + + ++  K+ + YG P N+D++ G V E     G VGP L+C++  QF++LRDGDRFW+E+   F   Q   + Q++L RI+CDN+  I+ V +N  FM+ S   +F++CS +P LNL  W+E
Sbjct:   18 CWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLR---------SLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ----DKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITI-------RNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNT-GITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743          

Query:  814 APKFIERPQDAYVAVGDKIRFACQVENINETKVEWHF---QFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNN--LVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFR-QPSLAALELAKASDVYEKVLDDLTGILRENKVK---LNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR-----PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAH-VPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGI--KRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVF-FMAKSKLEFIDCSNIPRLNLIPWKECYD 3525
            +P+F  +P+D     G +++  C+V    +  + W+    +F  +    L   N  L I    E   G Y C A N+ G +  +  L +  +  P I EGP S+S   G  V F C+A+G PVP+ TW +  S    ++  G+++V  +   L I NI E + EG Y C A +  G+    A +T+I  +         ++  +  ++  E L  I + A+  +  A +KT ++L   ++  + +D++ LFR      A+EL+KA ++YE+ +     ++RE+  K   LN+   + + + + ++L    +  +  LSGC     +  C+   CFH +YRS DG+CNN   P  G +L P  RL+KP YENG NTP+GW  G+LY+GY  P+ R VS +L+    ITP   LS+MVMQWGQF+DHDL  T    S   ++ G  CN TC N  PCF I   P DPRV+      PCI F RS A CGSG++S++  ++ YREQ+N +TSFLD SNVY S+ ++A ELRD   + G LR    + + K  LPF     +DC+ + ++ + + CF AGD R NE L L   HTI++REHNR++ +L+ +N +W+G+ IY+E+RKIVGAMMQHITY  W+PI+ G +    K +G Y GY+  VD+++++ FATAA RFGHT+INP L+RL  +F  I EG++ LHKAFF P+ V+  GG+DP+LRGLFA   K     Q++N ELIEKLF   HEV+LDL  +NIQR RDHGL SY  +R+FC +     ++D  G I    I +K+R +YG P N+DL+ G ++E+K+  GL GPT +C++ +QF+++RDGDRFWYE    F P QL +IK++TLAR+ CDN DNI R+Q++VF +    K  +  C     +NL  W +C D
Sbjct:  314 SPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGNPVPDYTWSFDGSTIGHIK--GRFMVSDDGTELRISNI-EKKDEGYYSCMAGNPVGAMSADAKLTVIGGE---------TRKAAAPQIDEELLRAIAQKARQNVENAVEKTRKQLTQ-DKVTNTNDLKRLFRFSTPKQAVELSKAREIYEESVR----LVREHVEKGLILNVDELHPKNVSYESVLHVTHVQALMGLSGCHTGQYKNPCTDT-CFHHRYRSFDGQCNNKNKPMTGVSLMPLRRLLKPVYENGFNTPVGWEKGRLYNGYPLPNVREVSRQLVATENITPHSKLSSMVMQWGQFVDHDLTHTVTALSRHSYATGAFCNRTCENLDPCFNIPLSPNDPRVKSGSAKYPCIEFERSAAVCGSGETSLVFNRVTYREQMNALTSFLDASNVYGSNEVQAQELRDTYNNNGMLRFDITSEAGKEYLPFEKDSNMDCRRNFSEENPIRCFLAGDLRANEQLALAATHTIFIREHNRIAKKLKSMNGNWDGEIIYHETRKIVGAMMQHITYKHWMPIIFGGQAQMNKFVGTYQGYDPDVDASVTNAFATAAFRFGHTIINPSLFRLGNDFMPIKEGHIALHKAFFTPELVLTQGGVDPLLRGLFASPLKHPMPTQLLNMELIEKLFMKGHEVSLDLAVMNIQRSRDHGLPSYTEYRKFCNLPVPVQWEDMKGYIKDDMIIQKLRGLYGVPQNIDLWVGGIVEEKLENGLFGPTFACIIGEQFRKIRDGDRFWYEKDGVFTPEQLREIKKITLARLFCDNGDNIDRIQKDVFMYPGMDKENYGTCQETEMMNLRAWSKCCD 1217          

Query:  172 MNFFIVIIFLGSLNFLSVSTTGQECLPQCRCTEK--TVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENAL-----------------YGPIF------LETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISL-EKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQK------------PYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRS 1365
            MN +++++ + + ++  V+  G EC  +C C +K   V C   G   IP+  ++ +  L +  N I K+  +  + F  L  + L+ NKI ++EEN L                 Y P        L +L LK N I+++ EQ+   +   L  L  ++NR+++L   L + L  +    L+ N  +C C        L+++  + +K  C +P+ +++Q L+EV  + L C+   E S                 G++I+  C  +N +   V W ++  +   +SL          + +E H+ +       N   ++ +      P+ +            P     P   S  +GS V+ +C   G P P I W    + +  + +  + +   NN++       E  GRY C A +  G  + +  + LI S
Sbjct:    1 MNLYLLLLVIATSSWQFVA--GLECPVECTCDKKGLVVDCSSSGLTRIPKNISRNVRSLVIRNNRIHKLKRSDLEGFNQLETLVLTHNKIKIIEENVLDHLPELKRLSLAHNELVYIPPLCSDSRPLASLNLKRNHIQFIDEQVL-RYFPDLTQLDFSHNRIQSLRTKLFDNLPALSHAHLHSNPWHCDCRASKVKALLQKVKWE-KKVYCTNPVELRHQALDEVDDSALTCARPAEES---------------WTGEEIKLTC-AKNSSSKLVVWMYENVEVDSSSL----------DGYEIHDTVITVPRKTNVNFMTCTYDFDHIPHHRRLRQSQHQGNGSPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWY--HNGKRFISSRKRQLGLSNNVLRIYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISS 405          

Query: 1006 GIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNN--LVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFR-QPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETL-----DFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV------QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAH-VPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRL-GQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFID-CSNIPRLNLIPWKECYDP----SRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSK 3624
            G Y C ASN + S S    + +  +++P I++ P   +A  G +V   C A G+PVP++ WL+      R  T  +Y +  NN  L IE +T  +  G + C A +  GSA  +A + L+ ++    L E+  KL     L +  + +I K+A+ K+  A   T ++ R  ++  S +D+  LF+   +L  ++L KA ++YE+ +       R  ++ ++   A+E  +      +  +L    +  + + SGCQ       C    CF  KYRS DG+CNN  +P  G +   F RL+ P YENG NTP+GW  GK Y+GY  P+AR VS  L+   + TP  +LSAM MQWGQF+DHDL  T    +   + +G  CN TC N  PCF I     DP++      + PC+ F R+ A CGSG++S I  ++ YR+Q+N +TS+LD S +Y +   +A ELRDL  D G LR   V+ +NK  +PF     +DC+ + ++ + + CF AGD R NE LGL+ MHTI++REHNR++  L  +N +W+G+ I+ E+RK++GAM+QHITYNAWLP +LG      + G+Y GYN  V+ TI++ FATAA+RF HTLIN  L+R D++F+   +G+LPLH AFFAP+R++ +GG+DP+LRGLFA   K  + DQV+N EL EKLF   HEVALDL ALNIQRGRDHGL S+  +R+FC +   +T+ D    + +  +  K++ +YG   N+DL+ G V E++ +  L+GPTL+C++ DQFKRLRDGDRFWYE+ + F  AQL QIK+VTL++I+C N D+I R+QR++F    +  +F + C ++P +NL  W  C D     S     + + G   ++ R+  +    ++C  K
Sbjct:  418 GQYECVASNGEESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRIPRRNT--RYTISDNNIELTIEKVTRHD-SGVFTCQAVNSVGSAVATANL-LVGAE----LTEKVDKL-----LDDSTIEKIAKEAKQKVEKALSSTKDQQR-MDKIESPNDLSKLFKFAINLKKVDLGKAREIYEESI-------RLVQMHIDNGLAFESAMISPNVSYEAVLPVSYVQTLMEKSGCQTGQFAESCEDH-CFFSKYRSYDGQCNNHEHPWWGVSEMAFMRLLPPRYENGFNTPVGWEKGKRYNGYEVPNARKVSRVLIGTDETTPHSHLSAMTMQWGQFIDHDLTLTAPALTRHSYKEGAFCNRTCENADPCFNIQLEADDPKLHTGLYQKHPCMEFERNGAACGSGETSPIFQRVTYRDQLNLLTSYLDASGIYGNSEEQALELRDLYSDHGLLRFDIVSGANKPYMPFEKDSDMDCRRNFSRENPIKCFLAGDVRANEQLGLMSMHTIFLREHNRIASRLLEVNENWDGETIFQETRKLIGAMLQHITYNAWLPKILGKATYNTIIGEYKGYNPDVNPTIANEFATAALRFAHTLINTHLFRFDKDFKETKQGHLPLHNAFFAPERLVSEGGVDPLLRGLFAAPIKMPRPDQVLNKELTEKLFNRFHEVALDLAALNIQRGRDHGLPSWTEYRKFCNLTVPKTWSDMKNIVQNDTVISKLQSLYGVTENIDLWVGGVTEKRTADALMGPTLACIIADQFKRLRDGDRFWYENEEMFSKAQLRQIKKVTLSKIICTNGDDIDRIQRDIFVYHGNSTQFYEPCESLPEINLNMWTTCCDAMCSSSSTLARNAIGGDEKAKRRKRRHHHSKKSCHDK 1289          

Query: 1582 AKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLIN-PRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVN-DSPCFPILTPPGDPRV---QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFN---IRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE 3516
            A+  D+    +     + RE  V         +T+D       +Q+   +  + C    +E  C   +C++  +R++DG CNN+   P RG++  P+ RL+   Y+N ++ P+G     L+   ++PS R ++ RL  +      P+ +A++MQ+GQF+ HD+  T +  S+        CN  C N  S C  +     D      Q  CI  SRS   CGSG        L  R+Q+N+ T ++D S +Y S   ++ + RD   + G L++ P+  + K  LPF+    R +  C +         F AGD R N  +GL   HTI+  EHNRL    + LN HW+G+++Y E+RK++GA +Q I Y  WLP VLG+     +G Y GY+  VDST+++ F +AA RFGH +I     RLD +F  I  G LP  K     D ++ +GG+DP++RG+F   S+ VK  Q +   + E +F      + DL  +NIQRGRDHG  +Y  +RE CGM  A  F+  S EI+++  R K++++YG    +DL+ GA+LE  +  GLVGPT++C++  QFKR RDGDRF+YE+   F   QL +I++ +L+RI+CDN++ IS + R  F +       + CS IP ++L  W++
Sbjct:  256 ARCRDIINDPIVAAEDMWRERLVVATEDNTRRQTVDL------DQVIRSNTANACTPRLDEADCEANICYNAMFRTLDGTCNNMKGEPLRGASYRPYTRLLPTIYDNEVSEPVG----SLFTD-ARPSPREITRRLTSSQASVESPDYNALIMQFGQFISHDMAKTTLVPSSK-------CN-VCQNITSRCMSVPITFDDSNANFRQAQCIRVSRSSPICGSGN-------LKPRQQLNENTGYIDASPIYGSSVHDSKKFRD--GNSGFLKL-PMF-NGKAFLPFDQNKCRNRGQCSV--------IFTAGDSRVNLFVGLSAWHTIFTEEHNRLVTAFKRLNPHWDGERLYQEARKMIGAQVQAIVYREWLPKVLGASFATVVGDYRGYDSDVDSTVANEFTSAAFRFGHGMIQEFYQRLDNSFRNISFGALPFQKGTLHSDVLVNEGGVDPLIRGMF---SQNVKRPQRVTTTVTENMFG-----STDLSTINIQRGRDHGHPAYVKYRELCGMGTAFNFEHLSREILNTGTRNKLQEIYGSVDKIDLWVGALLEDPIIRGLVGPTVACIIGPQFKRTRDGDRFYYENPGVFSRRQLVEIRKSSLSRIICDNTNTISTIPREAFRVG----HMVPCSQIPSMDLNQWRD 858          

Query: 1582 AKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLIN-PRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVN-DSPCFPILTPPGDPRV---QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFN---IRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE 3516
            A+  D+    +     + RE  V         +T+D       +Q+   +  + C    +E  C   +C++  +R++DG CNN+   P RG++  P+ RL+   Y+N ++ P+G     L+   ++PS R ++ RL  +      P+ +A++MQ+GQF+ HD+  T +  S+        CN  C N  S C  +     D      Q  CI  SRS   CGSG        L  R+Q+N+ T ++D S +Y S   ++ + RD   + G L++ P+  + K  LPF+    R +  C +         F AGD R N  +GL   HTI+  EHNRL    + LN HW+G+++Y E+RK++GA +Q I Y  WLP VLG+     +G Y GY+  VDST+++ F +AA RFGH +I     RLD +F  I  G LP  K     D ++ +GG+DP++RG+F   S+ VK  Q +   + E +F      + DL  +NIQRGRDHG  +Y  +RE CGM  A  F+  S EI+++  R K++++YG    +DL+ GA+LE  +  GLVGPT++C++  QFKR RDGDRF+YE+   F   QL +I++ +L+RI+CDN++ IS + R  F +       + CS IP ++L  W++
Sbjct:  256 ARCRDIINDPIVAAEDMWRERLVVATEDNTRRQTVDL------DQVIRSNTANACTPRLDEADCEANICYNAMFRTLDGTCNNMKGEPLRGASYRPYTRLLPTIYDNEVSEPVG----SLFTD-ARPSPREITRRLTSSQASVESPDYNALIMQFGQFISHDMAKTTLVPSSK-------CN-VCQNITSRCMSVPITFDDSNANFRQAQCIRVSRSSPICGSGN-------LKPRQQLNENTGYIDASPIYGSSVHDSKKFRD--GNSGFLKL-PMF-NGKAFLPFDQNKCRNRGQCSV--------IFTAGDSRVNLFVGLSAWHTIFTEEHNRLVTAFKRLNPHWDGERLYQEARKMIGAQVQAIVYREWLPKVLGASFATVVGDYRGYDSDVDSTVANEFTSAAFRFGHGMIQEFYQRLDNSFRNISFGALPFQKGTLHSDVLVNEGGVDPLIRGMF---SQNVKRPQRVTTTVTENMFG-----STDLSTINIQRGRDHGHPAYVKYRELCGMGTAFNFEHLSREILNTGTRNKLQEIYGSVDKIDLWVGALLEDPIIRGLVGPTVACIIGPQFKRTRDGDRFYYENPGVFSRRQLVEIRKSSLSRIICDNTNTISTIPREAFRVG----HMVPCSQIPSMDLNQWRD 858          

Query: 1687 DFTTLLTPEQLAIISQLS-----------GCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR-PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKL---RVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAK-SKLEFIDCSNIPRLNLIPWKE 3516
            D T + T E  +I   LS            C  + E  +C++ LC+H +YRS DG CNNL  P  GSA +   RL  P Y+NG+N P   T+  L    S+PSAR  +SRLL +       + +A++MQWGQF+ HDL       S +   +   C     N   C  +     DP   R  C+  +RS   CG+G S       ++REQ N+ T+F+DGS +Y S   +    R   + + KL   RV P    N  ++                       AGD R N  +GL  +H +++R+HNR++  L+ +N HW+ +++++ESRKIVGAM+Q IT+  +LP VLG    +R+G YPGY+  +D ++++ F + A RFGH +I      L+E F+ +  G +P +   F    ++ + GIDP++RGL  + +K     Q +   + E++F  +     DLG++NIQRGRDHG+  Y  WR+FCG+ + + F+     I +  + + ++ VY H   +D++ G++LE  V   LVGPTLSC++ +QFKR R+GDR WYE+   F P QL QIK++T++R+LCD  ++   V R  F + K +    + C  IP L+   WKE
Sbjct:  155 DCTFITTNEDTSIRKTLSIRDVRDSNANFNCAPTQETPNCNRNLCYHLRYRSFDGTCNNLKKPMIGSAFTALMRLKNPMYDNGLNAP---TSSFLR---SRPSAR-DASRLLLSSSTQIQHHSNALLMQWGQFIAHDL-------SKTTMLNNQECAACTSNKGRCTSVFLSRSDPTFGRFMCLPVARSTPVCGTGVS-------NFREQFNENTAFIDGSMIYGSSDRDQFLFRQGAFLKTKLINNRVFPPVDKNNNVV-----------------------AGDDRANIFVGLASLHVLYLRQHNRIAATLQRVNPHWDQERVFHESRKIVGAMIQRITFTEYLPKVLGVAFEERIGAYPGYDPNIDPSVANEFTSCAFRFGHGMIQEFYPFLNEKFQHV--GGIPFNDGMFKSTHIL-NNGIDPLIRGLMTLPAKM---PQRLTPAVTERIFGNS-----DLGSINIQRGRDHGVPPYTVWRKFCGLPEVKDFEGLKQVISNQVVIDNLKVVYKHVDAIDMYVGSLLEDPVKDALVGPTLSCIIGEQFKRTRNGDRLWYENSKVFSPEQLLQIKKITMSRVLCDAGEHFPMVPRKAFSVFKPTAHNLVKCDEIPDLDYNAWKE 725          

Query:  796 FEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNS----LYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKP-YIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQV---RLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKL---RDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQ-RPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNI-RGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE---CYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQC-SSNISNL----EERIKSLED 3684
             E  EL P+ +  PQ   + +G      C  +      ++W         N+    L   N  L +    + H G+Y CTA N  G  S  A +K+  +Q P  +   P+++ A  G+ +E  C+A   P   +   W    ++    ++   KY I    +L ++N+T  +  GRY C   +  G A  SA++T IR+  +L   +   ++                +A  +I++A   T + L   R      +  ++  +FR P+  A +LA+A+++YE+ L ++   ++E     NLT   EE  +F  LL+ E L ++++LSGC    E  +C+  +CFH +YRSIDG CNNL +P  G++L+ F RL  P YENG + P+GWT G LY G++KPSARLVS+ L+   +ITPD  ++ MVMQWGQFLDHDLD   + + +S   DG+ C ++C    PC+PI  PP DPRV+ R CI   RS A CGSG +S+    + +REQ+NQ+TS++D S VY      A ELR+LT  EG LRVG   P  K +LPF   +  +DC+ +  +  + CF +GD R NE +GLL MHTIWMREHNR++ +L+ +N+HW+GD +Y E+RKIVGA MQHIT+  WLP+++G  G++ +G+Y GYN  ++ +I++ FATAA+RFGHT+INPIL+RL+E F+ IP+G+L LHKAFFAP R+  +GG+DP++RG  A+ +K    DQ +N EL EKLF  AH VALDL A+NIQRGRDHG+  YN +R+ C +  A+ F+D +GEI S+EIR+KM+++YGHP NVD++ G +LE +V GG VGP   CLL++QF+RLRDGDR +YE+   F P QL+QIKQ    R+LCD  DN  +V  NVF +AK +  +  C +I  +NL  W+E   C  P  +  +  +P     RS R   +   +N +  T +   S + +L    EER+  LE+
Sbjct:  452 IELKEL-PEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQAD-QPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPD-GGRYECQLKNQFGRASASALVT-IRNNVDLAPGDRYVRI-------------AFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYERTLVNIRKHVQEGD---NLTMKSEE-YEFRDLLSREHLHLVAELSGCMEHREMPNCTD-MCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHA-IPSVSSESWDGIDCKKSCEMAPPCYPIEVPPNDPRVRNRRCIDVVRSSAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFPRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNSPPAIF-DSYIPQTYTKRSNRQKRDLGKENDEVATAESYDSPLESLYDVNEERVSGLEE 1412          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXX-----------------------XXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKS------QCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTF----NSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPAS-------------------------------------ISAEKGS-RVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C   C C E+TV C R     +P++     T L L  N I ++ AN F     L  + L+ N+++ +++ AL G   L  +YL NN +  LP  IF                                L + NN+L  LP+    +L N+KRL L GN + C C +       RR  LD Q+        C +P  ++NQ      F+ L  + F+ ++  P+F+  PQDA VA G+++  +C+V  +   ++ W     +        +    +  L I+       GIY C A N  G++  S  +++  N   + ++ P                                       I A  GS  V   C A G+P P+I W +V   Q+   T    +    +L++    +    G Y C A +  GS + +A I L
Sbjct:   26 CPAGCTCLERTVRCIRAKLSAVPKLPQDTQT-LDLRFNHIEELPANAFSGLAQLTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSL---WRRWHLDVQRQLVSISLTCAAPQMLQNQ-----GFSSLGEHHFKCAK--PQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMGALR-SQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQW-FVNGRQLLQSTPSLQLQANGSLILLQPNQLSA-GTYRCEARNSLGSVQATARIEL 454          

Query:  823 FIERPQDAYVAV--GDKIRFACQVENINETKVEWHF---QFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL--ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKL 1404
            F  +P D  VA+     +   C      +  ++W     Q   +T +     N  L + + ++   G Y C A N+ GS+ A+A++++   + P I+  P S + + G      C A G P+P I W   + N V L   T    +  +N  ++      E  G Y C A + +G   V A I + RS++   L  E S L
Sbjct:  367 FTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIEL--KELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDW---QLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNL 562          

Query:  796 FEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNS----LYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKP-YIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQV---RLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKL---RDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQ-RPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNI-RGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE---CYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQC-SSNISNL----EERIKSLED 3684
             E  EL P+ +  PQ   + +G      C  +      ++W         N+    L   N  L +    + H G+Y CTA N  G  S  A +K+  +Q P  +   P+++ A  G+ +E  C+A   P   +   W    ++    ++   KY I    +L ++N+T  +  GRY C   +  G A  SA++T IR+  +L   +   ++                +A  +I++A   T + L   R      +  ++  +FR P+  A +LA+A+++YE+ L ++   ++E     NLT   EE  +F  LL+ E L ++++LSGC    E  +C+  +CFH +YRSIDG CNNL +P  G++L+ F RL  P YENG + P+GWT G LY G++KPSARLVS+ L+   +ITPD  ++ MVMQWGQFLDHDLD   + + +S   DG+ C ++C    PC+PI  PP DPRV+ R CI   RS A CGSG +S+    + +REQ+NQ+TS++D S VY      A ELR+LT  EG LRVG   P  K +LPF   +  +DC+ +  +  + CF +GD R NE +GLL MHTIWMREHNR++ +L+ +N+HW+GD +Y E+RKIVGA MQHIT+  WLP+++G  G++ +G+Y GYN  ++ +I++ FATAA+RFGHT+INPIL+RL+E F+ IP+G+L LHKAFFAP R+  +GG+DP++RG  A+ +K    DQ +N EL EKLF  AH VALDL A+NIQRGRDHG+  YN +R+ C +  A+ F+D +GEI S+EIR+KM+++YGHP NVD++ G +LE +V GG VGP   CLL++QF+RLRDGDR +YE+   F P QL+QIKQ    R+LCD  DN  +V  NVF +AK +  +  C +I  +NL  W+E   C  P  +  +  +P     RS R   +   +N +  T +   S + +L    EER+  LE+
Sbjct:  452 IELKEL-PEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQAD-QPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPD-GGRYECQLKNQFGRASASALVT-IRNNVDLAPGDRYVRI-------------AFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYERTLVNIRKHVQEGD---NLTMKSEE-YEFRDLLSREHLHLVAELSGCMEHREMPNCTD-MCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHA-IPSVSSESWDGIDCKKSCEMAPPCYPIEVPPNDPRVRNRRCIDVVRSSAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFPRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNSPPAIF-DSYIPQTYTKRSNRQKRDLGKENDEVATAESYDSPLESLYDVNEERVSGLEE 1412          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXX-----------------------XXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKS------QCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTF----NSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPAS-------------------------------------ISAEKGS-RVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C   C C E+TV C R     +P++     T L L  N I ++ AN F     L  + L+ N+++ +++ AL G   L  +YL NN +  LP  IF                                L + NN+L  LP+    +L N+KRL L GN + C C +       RR  LD Q+        C +P  ++NQ      F+ L  + F+ ++  P+F+  PQDA VA G+++  +C+V  +   ++ W     +        +    +  L I+       GIY C A N  G++  S  +++  N   + ++ P                                       I A  GS  V   C A G+P P+I W +V   Q+   T    +    +L++    +    G Y C A +  GS + +A I L
Sbjct:   26 CPAGCTCLERTVRCIRAKLSAVPKLPQDTQT-LDLRFNHIEELPANAFSGLAQLTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSL---WRRWHLDVQRQLVSISLTCAAPQMLQNQ-----GFSSLGEHHFKCAK--PQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMGALR-SQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQW-FVNGRQLLQSTPSLQLQANGSLILLQPNQLSA-GTYRCEARNSLGSVQATARIEL 454          

Query:  823 FIERPQDAYVAV--GDKIRFACQVENINETKVEWHF---QFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL--ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKL 1404
            F  +P D  VA+     +   C      +  ++W     Q   +T +     N  L + + ++   G Y C A N+ GS+ A+A++++   + P I+  P S + + G      C A G P+P I W   + N V L   T    +  +N  ++      E  G Y C A + +G   V A I + RS++   L  E S L
Sbjct:  367 FTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIEL--KELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDW---QLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNL 562          

Query:  796 FEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNS----LYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKP-YIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQV---RLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKL---RDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQ-RPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNI-RGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE---CYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQC-SSNISNL----EERIKSLED 3684
             E  EL P+ +  PQ   + +G      C  +      ++W         N+    L   N  L +    + H G+Y CTA N  G  S  A +K+  +Q P  +   P+++ A  G+ +E  C+A   P   +   W    ++    ++   KY I    +L ++N+T  +  GRY C   +  G A  SA++T IR+  +L   +   ++                +A  +I++A   T + L   R      +  ++  +FR P+  A +LA+A+++YE+ L ++   ++E     NLT   EE  +F  LL+ E L ++++LSGC    E  +C+  +CFH +YRSIDG CNNL +P  G++L+ F RL  P YENG + P+GWT G LY G++KPSARLVS+ L+   +ITPD  ++ MVMQWGQFLDHDLD   + + +S   DG+ C ++C    PC+PI  PP DPRV+ R CI   RS A CGSG +S+    + +REQ+NQ+TS++D S VY      A ELR+LT  EG LRVG   P  K +LPF   +  +DC+ +  +  + CF +GD R NE +GLL MHTIWMREHNR++ +L+ +N+HW+GD +Y E+RKIVGA MQHIT+  WLP+++G  G++ +G+Y GYN  ++ +I++ FATAA+RFGHT+INPIL+RL+E F+ IP+G+L LHKAFFAP R+  +GG+DP++RG  A+ +K    DQ +N EL EKLF  AH VALDL A+NIQRGRDHG+  YN +R+ C +  A+ F+D +GEI S+EIR+KM+++YGHP NVD++ G +LE +V GG VGP   CLL++QF+RLRDGDR +YE+   F P QL+QIKQ    R+LCD  DN  +V  NVF +AK +  +  C +I  +NL  W+E   C  P  +  +  +P     RS R   +   +N +  T +   S + +L    EER+  LE+
Sbjct:  452 IELKEL-PEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQAD-QPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPD-GGRYECQLKNQFGRASASALVT-IRNNVDLAPGDRYVRI-------------AFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYERTLVNIRKHVQEGD---NLTMKSEE-YEFRDLLSREHLHLVAELSGCMEHREMPNCTD-MCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHA-IPSVSSESWDGIDCKKSCEMAPPCYPIEVPPNDPRVRNRRCIDVVRSSAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFPRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNSPPAIF-DSYIPQTYTKRSNRQKRDLGKENDEVATAESYDSPLESLYDVNEERVSGLEE 1412          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXX-----------------------XXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKS------QCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTF----NSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPAS-------------------------------------ISAEKGS-RVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C   C C E+TV C R     +P++     T L L  N I ++ AN F     L  + L+ N+++ +++ AL G   L  +YL NN +  LP  IF                                L + NN+L  LP+    +L N+KRL L GN + C C +       RR  LD Q+        C +P  ++NQ      F+ L  + F+ ++  P+F+  PQDA VA G+++  +C+V  +   ++ W     +        +    +  L I+       GIY C A N  G++  S  +++  N   + ++ P                                       I A  GS  V   C A G+P P+I W +V   Q+   T    +    +L++    +    G Y C A +  GS + +A I L
Sbjct:   26 CPAGCTCLERTVRCIRAKLSAVPKLPQDTQT-LDLRFNHIEELPANAFSGLAQLTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSL---WRRWHLDVQRQLVSISLTCAAPQMLQNQ-----GFSSLGEHHFKCAK--PQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMGALR-SQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQW-FVNGRQLLQSTPSLQLQANGSLILLQPNQLSA-GTYRCEARNSLGSVQATARIEL 454          

Query:  823 FIERPQDAYVAV--GDKIRFACQVENINETKVEWHF---QFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL--ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKL 1404
            F  +P D  VA+     +   C      +  ++W     Q   +T +     N  L + + ++   G Y C A N+ GS+ A+A++++   + P I+  P S + + G      C A G P+P I W   + N V L   T    +  +N  ++      E  G Y C A + +G   V A I + RS++   L  E S L
Sbjct:  367 FTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIEL--KELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDW---QLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNL 562          

Query:  796 FEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNS----LYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKP-YIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQV---RLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKL---RDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQ-RPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNI-RGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE---CYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQC-SSNISNL----EERIKSLED 3684
             E  EL P+ +  PQ   + +G      C  +      ++W         N+    L   N  L +    + H G+Y CTA N  G  S  A +K+  +Q P  +   P+++ A  G+ +E  C+A   P   +   W    ++    ++   KY I    +L ++N+T  +  GRY C   +  G A  SA++T IR+  +L   +   ++                +A  +I++A   T + L   R      +  ++  +FR P+  A +LA+A+++YE+ L ++   ++E     NLT   EE  +F  LL+ E L ++++LSGC    E  +C+  +CFH +YRSIDG CNNL +P  G++L+ F RL  P YENG + P+GWT G LY G++KPSARLVS+ L+   +ITPD  ++ MVMQWGQFLDHDLD   + + +S   DG+ C ++C    PC+PI  PP DPRV+ R CI   RS A CGSG +S+    + +REQ+NQ+TS++D S VY      A ELR+LT  EG LRVG   P  K +LPF   +  +DC+ +  +  + CF +GD R NE +GLL MHTIWMREHNR++ +L+ +N+HW+GD +Y E+RKIVGA MQHIT+  WLP+++G  G++ +G+Y GYN  ++ +I++ FATAA+RFGHT+INPIL+RL+E F+ IP+G+L LHKAFFAP R+  +GG+DP++RG  A+ +K    DQ +N EL EKLF  AH VALDL A+NIQRGRDHG+  YN +R+ C +  A+ F+D +GEI S+EIR+KM+++YGHP NVD++ G +LE +V GG VGP   CLL++QF+RLRDGDR +YE+   F P QL+QIKQ    R+LCD  DN  +V  NVF +AK +  +  C +I  +NL  W+E   C  P  +  +  +P     RS R   +   +N +  T +   S + +L    EER+  LE+
Sbjct:  452 IELKEL-PEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQAD-QPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPD-GGRYECQLKNQFGRASASALVT-IRNNVDLAPGDRYVRI-------------AFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYERTLVNIRKHVQEGD---NLTMKSEE-YEFRDLLSREHLHLVAELSGCMEHREMPNCTD-MCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHA-IPSVSSESWDGIDCKKSCEMAPPCYPIEVPPNDPRVRNRRCIDVVRSSAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFPRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNSPPAIF-DSYIPQTYTKRSNRQKRDLGKENDEVATAESYDSPLESLYDVNEERVSGLEE 1412          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXX-----------------------XXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKS------QCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTF----NSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPAS-------------------------------------ISAEKGS-RVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C   C C E+TV C R     +P++     T L L  N I ++ AN F     L  + L+ N+++ +++ AL G   L  +YL NN +  LP  IF                                L + NN+L  LP+    +L N+KRL L GN + C C +       RR  LD Q+        C +P  ++NQ      F+ L  + F+ ++  P+F+  PQDA VA G+++  +C+V  +   ++ W     +        +    +  L I+       GIY C A N  G++  S  +++  N   + ++ P                                       I A  GS  V   C A G+P P+I W +V   Q+   T    +    +L++    +    G Y C A +  GS + +A I L
Sbjct:   26 CPAGCTCLERTVRCIRAKLSAVPKLPQDTQT-LDLRFNHIEELPANAFSGLAQLTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSL---WRRWHLDVQRQLVSISLTCAAPQMLQNQ-----GFSSLGEHHFKCAK--PQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMGALR-SQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQW-FVNGRQLLQSTPSLQLQANGSLILLQPNQLSA-GTYRCEARNSLGSVQATARIEL 454          

Query:  823 FIERPQDAYVAV--GDKIRFACQVENINETKVEWHF---QFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL--ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKL 1404
            F  +P D  VA+     +   C      +  ++W     Q   +T +     N  L + + ++   G Y C A N+ GS+ A+A++++   + P I+  P S + + G      C A G P+P I W   + N V L   T    +  +N  ++      E  G Y C A + +G   V A I + RS++   L  E S L
Sbjct:  367 FTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIEL--KELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDW---QLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNL 562          

Query: 1639 ENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTP--IGWTAGKLYHGYSKPSARLVSSRLLRAHKITPD-PNL----SAMVMQWGQFLDHDLDFTPVDAS-NSRFSDGLGCNETCVNDSPCFPILTPPGD---PRV-----QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSE-----GIKRL--GQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFA--MAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHD---QFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLE-FIDCSNIPRLNLIPWKE 3516
            +N    N  T   +T+D + LL   Q     QL  C         SQQ   +  +R++ G+CNNL NP  G +L+ F RL+  +YE+GI+ P   G T      G + P+ R +S+       I PD  NL    S MVMQ+ QF+DHDL  TP+    +        CN        C P   P GD   P V     +R C    RS+     GQ S     L  R+Q+NQ T FLDGS VY      + +LR  +      R+       K LLP     +   +      +  CF  GD R +E  GL  +HT ++REHNR+ + LRG+N HWNG+++++ +RKIV A +QHI +N +LP +L        G+K L  G Y  YN      + + FA AA R GH+L+ P + RL    + + E  L L   FF  D +++ G ID ILRGL A   + +  DQ +  E+   LF         +DL ALNIQR RDHG+ SYN++R  C +K+A  ++D S EI  +E+  + +++Y    ++DLF GA+ E+ + GGLVGPTL+C++  QF++LR  DRFWYE+ +   +F  AQL+++++VTLA+I+C+N +    +QR  F +  + L   + C+++P+++L  W+E
Sbjct:  675 QNAFNRNELTDTLQTVDISGLLGGAQ----KQLDTCPEP------SQQCDANSPFRTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPRLTGVT------GTALPNPRTIST------TIHPDISNLHTRYSLMVMQFAQFVDHDLTLTPIHKGFHESIPSCRPCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLP----GQQS-----LGPRDQINQNTHFLDGSMVYGETTCLSNKLRGFSG-----RMNSTQVRGKELLPLGPHPECKSR------NGLCFLGGDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSWNAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQPV-EPPLLLRDGFFRMDALLQPGIIDEILRGLVATPMETL--DQFITGEVTNHLFEDRKIPFSGIDLIALNIQRARDHGIPSYNNYRALCNLKRATNWNDLSREI-PTEVINRFQKIYASVDDIDLFPGAMTERPLQGGLVGPTLACIIGIQFRQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENLEITGDMQRAAFDLPSNFLNPRVPCASMPQIDLNAWRE 1283          

Query: 1783 LCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLR-AHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSP----CFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLG-------QYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAE------TFDDFSG-EIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESH---DQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKL-EFIDCSNIPRLNLIPWKECYDPSRLTPED 3549
            +C   KYR    +CNN+ + + G+    F RL+  +Y +G++ P      K  H    P A +V  +L R         +++AM+  WGQ L +DL    V+      S      ++ V D      CF +   P     +R   GF   +  C          + H R+Q+N  ++++DGS +Y S   E  +LR  TY  G ++V                    CQ+  A                      +H   +++HN + + L  +N  W+ + ++ E+R+I+ A +QHITYN +LP+VLG E   + G           Y+  V   I + FATAAM                          P   + + P+ + +      +L  + A+    V S    NAE   +L            AL + RGRDHG+ASY    + C  + A+      +FD  +    +  E    +R +Y +  ++DL  GA+LE+ V G L GPT+SCLL  QF++L+  DRFWYE+      F   QL  I+Q TL+ +LC  S  +S  Q   F +  + L   +DC  +P+ +L PW+       + PED
Sbjct:   63 VCPPSKYRQPTAECNNVSHRKWGARGDIFQRLLAADYADGVSQP---RTSKGTHAL--PDAEVVIEQLQRHVEGELRHAHITAMLPAWGQLLANDL----VEVGQLPISGKCCERDSAVKDPSELQHCF-VRAGPDCKEYKRSAPGFD--LEAC----------QKHTRQQMNIASAYIDGSGLYGSTRHEFDQLR--TYISGGVKVESCK---------------YCQVAGATG-------------------ALHRALLQQHNNIGERLSHINPDWSEEDVFLEARRIITATIQHITYNEFLPLVLGQETTAKEGLRLTAEKHSSNYSSSVRGGIYNEFATAAM--------------------------PAFWSMYPPEMLAKKMSAHELL-SIAALQKSLVPSQ--TNAEGWSEL------------ALAVHRGRDHGVASYVHALDLCERRFADQSAANVSFDTLAQVSNIPEEYITNLRDIYQNANDIDLLVGALLEEPVVGALFGPTISCLLSLQFEQLKQTDRFWYENEIPPSSFTLDQLKSIRQTTLSGLLC-GSHQVSTAQSKAFILEDNYLNSILDCDQLPKFDLKPWQ-------VNPED 567          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR---PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLS------------------PSRSRRSTNEFQDQNCKSKTNQCSSNISNLEERIKSLEDKM 3690
            +N++   +  P+F   PQD  V  G  + F C+     +  + W    +    +   +      L I  V    +G Y C A +  G+  A+  L I  +  P     P  ++ E GS V+  C A G P P ITW     + V++   GK+ +  +  +  +       GRY C A +  G +  S V+T+              ++P  ++  +  +   +++A   IN A   T  +L D    R+ +++ +LFR P     +E A+A +++E+ L  +   + +  +     TAY     +  L++P  L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+PF RL+KP Y+NG N P G T  + ++GY  P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C   C ND PCFPI+ PP DPR +R    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA E+RDL    G LR G V  + K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W+REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITYN WLP +LG  G++ +G Y GYN  +++ I + FATAA RFGHTLINPILYRLDENF+ I +G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   S Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+ SYN +R FC +  A+TF+D   EI +  +REK++++YG P NVDLF   + E+ V G  +GPTL CLL  QFKRLRDGDRFWYE+   F PAQL+Q+KQ +L+R+LCDN DNI+R+Q + F +A     +  C+++P+++L  W++C +  R   + Q   LS                  PS +  S  +FQD             I++L ++IK LE ++
Sbjct:  413 ANAYIIVQARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSPLPNDRRHVVLSTGSLRISRVALHDQGQYECQAVSPVGTARAAVHLNILQSVTPVFTSAPRDLTVESGSDVQIPCSAQGEPTPIITW---SKDGVQITESGKFHINPDGYLEVHDVGLADGGRYECVARNSIGYSSSSMVLTV--------------QVPQVSREGDPFVSTSLEEAIRSINSAIDSTRRQLFD-GSPRTPAELLALFRYPRDPYTVEQARAGEIFEQTLLLIQRHVNQGLMVDTNGTAYR----YNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRTHDGTCNNLQHPMWGASLTPFERLLKPVYDNGFNLPRG-TTERWHNGYPLPLPRLVSTTMIGTETITPDDRYTHMLMQWGQFLDHDLDSTVVSLSQSRFSDGQLCTSVCTNDPPCFPIMFPPNDPRQRRNGARCMFFVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSQHEAEEIRDLASHRGMLRQGIVQRTGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTAMHTVWLREHNRIASELLRLNPHWDGDTIYHEARKIVGAQMQHITYNQWLPKILGEAGMRIMGDYTGYNPNINAGILNAFATAAFRFGHTLINPILYRLDENFQPIQQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRMSTQLLNTELTERLFSMAHAVALDLAAMNIQRGRDHGIPSYNDYRVFCNLTSAQTFEDLKNEIQNPSVREKLQRLYGTPLNVDLFPALMAEELVPGSRLGPTLMCLLATQFKRLRDGDRFWYENPGSFSPAQLTQLKQTSLSRVLCDNGDNITRIQSDAFSVADLPHGYGSCADLPKIDLRMWQDCCEDCRT--KGQFNALSFHFRGRRSAEHSYAEEKKPSSTEPSAKDFQD-----FVTDMQKTITSLRKQIKRLEGRV 1373          

Query:  190 IIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSL---------PGN---------------SISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASA---KLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            I+FL S     VS+    C  +C C   TV C     + +P +   + T L L         PG+                I +I    F++ ++L ++ L  N+I  ++  A  G + LE LYL  N IE L  + FS      +L    NNR+  L + +   L ++KRL L  N L+C CEL + A  L++    G     + C  P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      DT  N L   +  L I++  E  +G+Y C A N  G +  S    +   +P++  ++++ P +     G  V   C A G P P +T  W + +Q  L  + +  I     L I+NI +++  G+Y C+AS+   +   +A I +
Sbjct:   12 IVFLLSSGPYRVSS----CPSRCLCFRTTVRCMHLNLESVPAV-LPQTTILDLRFNKIKDLQPGSFKRLKNLNTLLLNNNHIRRIPRGAFEDLENLKYLYLYKNEIQAIDREAFKGLVSLEQLYLHFNNIESLEPESFSHLPKLERLFLH-NNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWLADLLKQYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCE--------VPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTSEVTLRYFRSPSRPSFVIQ-PQNTEVLVGESVTLECSATGQPQPRVT--WTRGDQSALPVDPRINITPSGGLFIQNIHQAD-GGQYTCFASNNVDTIHANAYIIV 419          

Query:  763 EVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWR-----NQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIV-RKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRS 1365
            EVK +E+    F  S   P F+ +PQ+  V VG+ +   C      + +V W     D +   +  R     +  LFI+ +H+   G Y C ASNN  +I A+A + +    +P     P   S  +G  V+F C A G+P P I W    S    L  + +++V    +L I  +   + +G+Y C A S  G+A+ +  + +++S
Sbjct:  315 EVKTSEVTLRYFR-SPSRPSFVIQPQNTEVLVGESVTLECSATGQPQPRVTW--TRGDQSALPVDPRINITPSGGLFIQNIHQADGGQYTCFASNNVDTIHANAYIIV--QARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSP---LPNDRRHVVLSTGSLRISRVALHD-QGQYECQAVSPVGTARAAVHLNILQS 512          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR---PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQCSSNISNLEERIKSLED 3684
            +N++   +  P+F   PQD  V  G  + F C+     +  + W    +    +   +      L I  V    +G Y C A +  G+  A+  L I  +  P     P  ++ E GS V+  C A G P P ITW     + V++   GK+ +  +  +  +       GRY C A +  G +  S V+T+              ++P  ++  +  +   +++A   IN A   T  +L D    R+ +++ +LFR P     +E A+A +++E+ L  +   + +  +     TAY     +  L++P  L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+PF RL+KP Y+NG N P G T  + ++GY  P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C   C ND PCFPI+ PP DPR +R    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA E+RDL    G LR G V  + K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W+REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITYN WLP +LG  G++ +G Y GYN  +++ I + FATAA RFGHTLINPILYRLDENF+ I +G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   S Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+ SYN +R FC +  A+TF+D   EI +  +REK++++YG P NVDLF   + E+ V G  +GPTL CLL  QFKRLRDGDRFWYE+   F PAQL+Q+KQ +L+R+LCDN DNI+R+Q + F +A     +  C+++P+++L  W++C +  R   + Q   LS     R + E      K   N  + N S+ E   K  +D
Sbjct:  383 ANAYIIVQARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSPLPNDRRHVVLSTGSLRISRVALHDQGQYECQAVSPVGTARAAVHLNILQSVTPVFTSAPRDLTVESGSDVQIPCSAQGEPTPIITW---SKDGVQITESGKFHINPDGYLEVHDVGLADGGRYECVARNSIGYSSSSMVLTV--------------QVPQVSREGDPFVSTSLEEAIRSINSAIDSTRRQLFD-GSPRTPAELLALFRYPRDPYTVEQARAGEIFEQTLLLIQRHVNQGLMVDTNGTAYR----YNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRTHDGTCNNLQHPMWGASLTPFERLLKPVYDNGFNLPRG-TTERWHNGYPLPLPRLVSTTMIGTETITPDDRYTHMLMQWGQFLDHDLDSTVVSLSQSRFSDGQLCTSVCTNDPPCFPIMFPPNDPRQRRNGARCMFFVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSQHEAEEIRDLASHRGMLRQGIVQRTGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTAMHTVWLREHNRIASELLRLNPHWDGDTIYHEARKIVGAQMQHITYNQWLPKILGEAGMRIMGDYTGYNPNINAGILNAFATAAFRFGHTLINPILYRLDENFQPIQQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRMSTQLLNTELTERLFSMAHAVALDLAAMNIQRGRDHGIPSYNDYRVFCNLTSAQTFEDLKNEIQNPSVREKLQRLYGTPLNVDLFPALMAEELVPGSRLGPTLMCLLATQFKRLRDGDRFWYENPGSFSPAQLTQLKQTSLSRVLCDNGDNITRIQSDAFSVADLPHGYGSCADLPKIDLRMWQDCCEDCRT--KGQFNALSFHFRGRRSAEHSYAEEKKPANNLTEN-SSTEPSAKDFQD 1327          

Query:  250 PQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSF--------NKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASA---KLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            P+C C   TV C     + +P +         LP  +I  +   +F + KDL    ++F        N+I  ++  A  G + LE LYL  N IE L  + FS      +L    NNR+  L + +   L ++KRL L  N L+C CEL + A  L++    G     + C  P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      DT  N L   +  L I++  E  +G+Y C A N  G +  S    +   +P++  ++++ P +     G  V   C A G P P +T  W + +Q  L  + +  I     L I+NI +++  G+Y C+AS+   +   +A I +
Sbjct:   25 PRCLCFRTTVRCMHLNLESVPAV---------LPQTTILDL---RFNKIKDLQPASITFFHFEYLYKNEIQAIDREAFKGLVSLEQLYLHFNNIESLEPESFSHLPKLERLFLH-NNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWLADLLKQYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCE--------VPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTSEVTLRYFRSPSRPSFVIQ-PQNTEVLVGESVTLECSATGQPQPRVT--WTRGDQSALPVDPRINITPSGGLFIQNIHQAD-GGQYTCFASNNVDTIHANAYIIV 389          

Query:  763 EVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWR-----NQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIV-RKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRS 1365
            EVK +E+    F  S   P F+ +PQ+  V VG+ +   C      + +V W     D +   +  R     +  LFI+ +H+   G Y C ASNN  +I A+A + +    +P     P   S  +G  V+F C A G+P P I W    S    L  + +++V    +L I  +   + +G+Y C A S  G+A+ +  + +++S
Sbjct:  285 EVKTSEVTLRYFR-SPSRPSFVIQPQNTEVLVGESVTLECSATGQPQPRVTW--TRGDQSALPVDPRINITPSGGLFIQNIHQADGGQYTCFASNNVDTIHANAYIIV--QARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSP---LPNDRRHVVLSTGSLRISRVALHD-QGQYECQAVSPVGTARAAVHLNILQS 482          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR---PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQCSSNIS 3651
            +N++   +  P+F   PQD  V  G  + F C+     +  + W    +    +   +      L I  V    +G Y C A +  G+  A+  L I  +  P     P  ++ E GS V+  C A G P P ITW     + V++   GK+ +  +  +  +       GRY C A +  G +  S V+T+              ++P  ++  +  +   +++A   IN A   T  +L D    R+ +++ +LFR P     +E A+A +++E+ L  +   + +  +     TAY     +  L++P  L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+PF RL+KP Y+NG N P G T  + ++GY  P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C   C ND PCFPI+ PP DPR +R    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA E+RDL    G LR G V  + K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W+REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITYN WLP +LG  G++ +G Y GYN  +++ I + FATAA RFGHTLINPILYRLDENF+ I +G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   S Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+ SYN +R FC +  A+TF+D   EI +  +REK++++YG P NVDLF   + E+ V G  +GPTL CLL  QFKRLRDGDRFWYE+   F PAQL+Q+KQ +L+R+LCDN DNI+R+Q + F +A     +  C+++P+++L  W++C +  R   + Q   LS     R + E      K   N  + NI+
Sbjct:  418 ANAYIIVQARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSPLPNDRRHVVLSTGSLRISRVALHDQGQYECQAVSPVGTARAAVHLNILQSVTPVFTSAPRDLTVESGSDVQIPCSAQGEPTPIITW---SKDGVQITESGKFHINPDGYLEVHDVGLADGGRYECVARNSIGYSSSSMVLTV--------------QVPQVSREGDPFVSTSLEEAIRSINSAIDSTRRQLFD-GSPRTPAELLALFRYPRDPYTVEQARAGEIFEQTLLLIQRHVNQGLMVDTNGTAYR----YNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRTHDGTCNNLQHPMWGASLTPFERLLKPVYDNGFNLPRG-TTERWHNGYPLPLPRLVSTTMIGTETITPDDRYTHMLMQWGQFLDHDLDSTVVSLSQSRFSDGQLCTSVCTNDPPCFPIMFPPNDPRQRRNGARCMFFVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSQHEAEEIRDLASHRGMLRQGIVQRTGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTAMHTVWLREHNRIASELLRLNPHWDGDTIYHEARKIVGAQMQHITYNQWLPKILGEAGMRIMGDYTGYNPNINAGILNAFATAAFRFGHTLINPILYRLDENFQPIQQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRMSTQLLNTELTERLFSMAHAVALDLAAMNIQRGRDHGIPSYNDYRVFCNLTSAQTFEDLKNEIQNPSVREKLQRLYGTPLNVDLFPALMAEELVPGSRLGPTLMCLLATQFKRLRDGDRFWYENPGSFSPAQLTQLKQTSLSRVLCDNGDNITRIQSDAFSVADLPHGYGSCADLPKIDLRMWQDCCEDCRT--KGQFNALSFHFRGRRSAEHSYAEEKKPANNLTENIN 1352          

Query:  184 IVIIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSL---------PGN---------------SISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASA---KLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            ++ +FL S     VS+    C  +C C   TV C     + +P +   + T L L         PG+                I +I    F++ ++L ++ L  N+I  ++  A  G + LE LYL  N IE L  + FS      +L    NNR+  L + +   L ++KRL L  N L+C CEL + A  L++    G     + C  P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      DT  N L   +  L I++  E  +G+Y C A N  G +  S    +   +P++  ++++ P +     G  V   C A G P P +T  W + +Q  L  + +  I     L I+NI +++  G+Y C+AS+   +   +A I +
Sbjct:   15 VLSVFLLSSGPYRVSS----CPSRCLCFRTTVRCMHLNLESVPAVL-PQTTILDLRFNKIKDLQPGSFKRLKNLNTLLLNNNHIRRIPRGAFEDLENLKYLYLYKNEIQAIDREAFKGLVSLEQLYLHFNNIESLEPESFSHLPKLERLFLH-NNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWLADLLKQYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCE--------VPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTSEVTLRYFRSPSRPSFVIQ-PQNTEVLVGESVTLECSATGQPQPRVT--WTRGDQSALPVDPRINITPSGGLFIQNIHQAD-GGQYTCFASNNVDTIHANAYIIV 424          

Query:  763 EVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWR-----NQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIV-RKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRS 1365
            EVK +E+    F  S   P F+ +PQ+  V VG+ +   C      + +V W     D +   +  R     +  LFI+ +H+   G Y C ASNN  +I A+A + +    +P     P   S  +G  V+F C A G+P P I W    S    L  + +++V    +L I  +   + +G+Y C A S  G+A+ +  + +++S
Sbjct:  320 EVKTSEVTLRYFR-SPSRPSFVIQPQNTEVLVGESVTLECSATGQPQPRVTW--TRGDQSALPVDPRINITPSGGLFIQNIHQADGGQYTCFASNNVDTIHANAYIIV--QARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSP---LPNDRRHVVLSTGSLRISRVALHD-QGQYECQAVSPVGTARAAVHLNILQS 517          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR---PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQCSSNIS 3651
            +N++   +  P+F   PQD  V  G  + F C+     +  + W    +    +   +      L I  V    +G Y C A +  G+  A+  L I  +  P     P  ++ E GS V+  C A G P P ITW     + V++   GK+ +  +  +  +       GRY C A +  G +  S V+T+              ++P  ++  +  +   +++A   IN A   T  +L D    R+ +++ +LFR P     +E A+A +++E+ L  +   + +  +     TAY     +  L++P  L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+PF RL+KP Y+NG N P G T  + ++GY  P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C   C ND PCFPI+ PP DPR +R    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA E+RDL    G LR G V  + K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W+REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITYN WLP +LG  G++ +G Y GYN  +++ I + FATAA RFGHTLINPILYRLDENF+ I +G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   S Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+ SYN +R FC +  A+TF+D   EI +  +REK++++YG P NVDLF   + E+ V G  +GPTL CLL  QFKRLRDGDRFWYE+   F PAQL+Q+KQ +L+R+LCDN DNI+R+Q + F +A     +  C+++P+++L  W++C +  R   + Q   LS     R + E      K   N  + NI+
Sbjct:  415 ANAYIIVQARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSPLPNDRRHVVLSTGSLRISRVALHDQGQYECQAVSPVGTARAAVHLNILQSVTPVFTSAPRDLTVESGSDVQIPCSAQGEPTPIITW---SKDGVQITESGKFHINPDGYLEVHDVGLADGGRYECVARNSIGYSSSSMVLTV--------------QVPQVSREGDPFVSTSLEEAIRSINSAIDSTRRQLFD-GSPRTPAELLALFRYPRDPYTVEQARAGEIFEQTLLLIQRHVNQGLMVDTNGTAYR----YNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRTHDGTCNNLQHPMWGASLTPFERLLKPVYDNGFNLPRG-TTERWHNGYPLPLPRLVSTTMIGTETITPDDRYTHMLMQWGQFLDHDLDSTVVSLSQSRFSDGQLCTSVCTNDPPCFPIMFPPNDPRQRRNGARCMFFVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSQHEAEEIRDLASHRGMLRQGIVQRTGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTAMHTVWLREHNRIASELLRLNPHWDGDTIYHEARKIVGAQMQHITYNQWLPKILGEAGMRIMGDYTGYNPNINAGILNAFATAAFRFGHTLINPILYRLDENFQPIQQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRMSTQLLNTELTERLFSMAHAVALDLAAMNIQRGRDHGIPSYNDYRVFCNLTSAQTFEDLKNEIQNPSVREKLQRLYGTPLNVDLFPALMAEELVPGSRLGPTLMCLLATQFKRLRDGDRFWYENPGSFSPAQLTQLKQTSLSRVLCDNGDNITRIQSDAFSVADLPHGYGSCADLPKIDLRMWQDCCEDCRT--KGQFNALSFHFRGRRSAEHSYAEEKKPANNLTENIN 1349          

Query:  250 PQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSL---------PGN---------------SISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASA---KLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            P+C C   TV C     + +P +   + T L L         PG+                I +I    F++ ++L ++ L  N+I  ++  A  G + LE LYL  N IE L  + FS      +L    NNR+  L + +   L ++KRL L  N L+C CEL + A  L++    G     + C  P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      DT  N L   +  L I++  E  +G+Y C A N  G +  S    +   +P++  ++++ P +     G  V   C A G P P +T  W + +Q  L  + +  I     L I+NI +++  G+Y C+AS+   +   +A I +
Sbjct:   30 PRCLCFRTTVRCMHLNLESVPAVL-PQTTILDLRFNKIKDLQPGSFKRLKNLNTLLLNNNHIRRIPRGAFEDLENLKYLYLYKNEIQAIDREAFKGLVSLEQLYLHFNNIESLEPESFSHLPKLERLFLH-NNRISHLALGTFSHLQSMKRLRLDSNALHCDCELLWLADLLKQYAESGNAQAAATCDYPNRLQGRSVATLTAHELNCE--------VPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTSEVTLRYFRSPSRPSFVIQ-PQNTEVLVGESVTLECSATGQPQPRVT--WTRGDQSALPVDPRINITPSGGLFIQNIHQAD-GGQYTCFASNNVDTIHANAYIIV 421          

Query:  763 EVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWR-----NQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIV-RKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRS 1365
            EVK +E+    F  S   P F+ +PQ+  V VG+ +   C      + +V W     D +   +  R     +  LFI+ +H+   G Y C ASNN  +I A+A + +    +P     P   S  +G  V+F C A G+P P I W    S    L  + +++V    +L I  +   + +G+Y C A S  G+A+ +  + +++S
Sbjct:  317 EVKTSEVTLRYFR-SPSRPSFVIQPQNTEVLVGESVTLECSATGQPQPRVTW--TRGDQSALPVDPRINITPSGGLFIQNIHQADGGQYTCFASNNVDTIHANAYIIV--QARPQFTVTPQDQSVLEGQTVDFPCEASGFPQPVIAWTRGGSP---LPNDRRHVVLSTGSLRISRVALHD-QGQYECQAVSPVGTARAAVHLNILQS 514          

Query: 1435 LYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDI------QSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHK--ITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP--CIGFSRSIATCGSGQSSIILGKL-HYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQI------DPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKR-LGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPE-GNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYD 3525
            + + I++A+  ++ A+K +    RD +  R R D+        L +QP+    E  +A+D   + L     ++ E    +     ++ +++ T LLT ++L  I++++GC+  T    C      +K YR+  G CNN  NP  G++ +PF R +  +YE+ ++ P GW   KLY+G + P  RLVS+R+L      I  D + + M+  +GQ++DHDL FTP   S   FS+G+ C  +C    PCFPI  PPGD R+ RP  C+   RS  TCGSG ++ + G++ + REQ+N +T++LD   VY S+   A ELRDLT D G LRV      N R LLPF       C        D     VPCF AGD R NEN  L  +HT+++REHNRL+  L  LN  W+ + +Y E+RKIVGA  Q +    +LP+++G +   R LG YPGYN+ VD TI++VFATAA RF H  I P ++RLDEN++  P+  ++PL++AFF+P RV+ +GGIDP+LRGL    +K    D ++   L E+LFA    +ALDL +LN+QRGRDH +  YN+WR FCG+   +   + +  + ++E+  K+ ++YG P N+D++ G V E    GG VG   +CL+  QF+++RDGDR W+ES+  F   Q + +  V+LARI+CDN+  I +V R+ F   +S   F++C NIP  +L PWKE  D
Sbjct:   30 ILDSIEEAKKIVDAAYKYS----RDESLARVRKDVIKPSDKLRLLKQPARKTREAVRAADYMAQTLR----LISEKAHHV-----HKRSINATNLLTQDELQTITRMTGCEAQTRPPSCRTTPLINK-YRTASGVCNNRKNPLLGASNTPFARWLPAQYEDAVSQPKGWDPNKLYNGAALPMVRLVSNRILATADADIESDHDFTFMLTIFGQWVDHDLTFTPFSPSIRSFSNGIDCENSCERSEPCFPISAPPGDQRL-RPNTCLPVFRSAPTCGSGHTAYMFGEVPNVREQINTLTAYLDAGQVYGSEDGLAKELRDLTNDGGLLRVNNRFKDNGRELLPFTSVNTNLCATRQKILNDSTLTEVPCFIAGDARVNENPALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVGPDAYNRHLGPYPGYNENVDPTIANVFATAAFRFAHLTIQPFIFRLDENYKNHPQFPSVPLYEAFFSPWRVIFEGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSHIALDLASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTELARKLIELYGTPENIDVWLGGVAEPFAPGGRVGSLFACLISRQFQKIRDGDRLWFESNGVFTTKQKTALASVSLARIICDNT-GILKVPRDPFRF-RSPANFVNCGNIPAFDLEPWKETGD 729          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLY--WRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR--PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            S ++   +  P+F   PQD  V  G  + F C+ +   +  + W    N  + +  +    +  L I  V    +G Y C A N  GS S +A+L +     P     P  ++ E G+ V+  C + G P+P ITW     + +++   GK+ +  +  +         +GRY C A +  G + VS V++++              +P  ++  +  +   I +A + ++ A   T   L D +R RS  D+ +LFR P     +E A+A++++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG N P G  +G++Y+G+  P  RLVS+ L+  H ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND+PCFPI+ PP DPRV+    C+   RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   E+ E+RD     G L+ G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP + G  G+K LG+Y  Y+  V++ I + FATAA RFGHTLINPILYRLDE FE IP+G++PLH+AFF+P R++ +GGIDP+LRGL  + +K   + Q++N EL EKLF+MAH VALDL ALN+QRGRDHG+  Y+ +R FC +   +TFDD   EI + ++REK++++YG P N+DLF   ++E  + G  +GPTL CLL  QF+ +RDGDRFWYE+   F  AQL+QIKQ +LAR+LCDN DNI++VQ ++F +A+    ++ C NI +++L  W++C +  R
Sbjct:  416 STAYIIVQAVPQFTVVPQDRNVFEGHTVDFHCEAQGNPKPVIAWTKGGNQLSVDRRHQVLSSGTLRILRVALHDQGQYECQAVNIVGSKSTAAQLIVQTRVTPVFATVPNDMTVEVGTDVQIPCSSQGDPLPIITW---NKDGIQVTESGKFHISPHGYLAIRDAGLADQGRYECVARNPIGYSSVSMVLSVL--------------VPEVSRTGDPFVATSIIEAIATVDRAINSTRTHLFD-SRPRSPGDLLALFRYPRDPYTVEQARAAEIFERTLQLIQDHVQSGLMVDLNGTSYH-----YNDLVSPQYLNMIANLSGCATHRRINNCSN-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNLPRG-ISGRIYNGFPLPLPRLVSTTLIGTHTITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQDCSVVCTNDAPCFPIMVPPNDPRVRNNARCMSMVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSDHESNEIRDSASHRGLLKQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDVGMKMLGEYKSYDPNVNAGILNEFATAAFRFGHTLINPILYRLDEKFEPIPQGHVPLHRAFFSPFRIVNEGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAALNVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPALMVEDLIPGSRLGPTLMCLLTTQFRNIRDGDRFWYENPGVFTAAQLTQIKQTSLARVLCDNGDNITKVQHDLFRVAEFPHGYVSCKNIAKMDLRVWQDCCEDCR 1312          

Query:  190 IIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGN------------------------SISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSIS---ASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            +     L  +++      C  +C C   TV C     + +P +     T L L  N                         I +I +  FK+ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L  + F+      +L    N     +P +  +L ++KRL L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  +GIY C A N  G +     + +    P    ++++ P +     G  V   C A G P P +T  W + ++  L ++ +  I     L I+N+ + +  G Y C+A++   +   +A I +
Sbjct:   11 LYLTAGLLVVALPQLSHSCPSRCLCFRTTVRCMHLMLESVPAVP-PHTTILDLRFNRIKDIQTGAFKHLKNLNTLLLNNNQIKRIPSEAFKDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSVSTITPSELNCER--------PRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLL--NDGTLMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRYYGTPATPTFVIQ-PQNTEVLVGESVTLECSATGQPHPRVT--WTRGDRTPLPSDPRINITPSGGLYIQNVNQDDA-GEYTCFATNSVETIHSTAYIIV 422          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLY--WRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR--PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            S ++   +  P+F   PQD  V  G  + F C+ +   +  + W    N  + +  +    +  L I  V    +G Y C A N  GS S +A+L +     P     P  ++ E G+ V+  C + G P+P ITW     + +++   GK+ +  +  +         +GRY C A +  G + VS V++++              +P  ++  +  +   I +A + ++ A   T   L D +R RS  D+ +LFR P     +E A+A++++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG N P G  +G++Y+G+  P  RLVS+ L+  H ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND+PCFPI+ PP DPRV+    C+   RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   E+ E+RD     G L+ G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP + G  G+K LG+Y  Y+  V++ I + FATAA RFGHTLINPILYRLDE FE IP+G++PLH+AFF+P R++ +GGIDP+LRGL  + +K   + Q++N EL EKLF+MAH VALDL ALN+QRGRDHG+  Y+ +R FC +   +TFDD   EI + ++REK++++YG P N+DLF   ++E  + G  +GPTL CLL  QF+ +RDGDRFWYE+   F  AQL+QIKQ +LAR+LCDN DNI++VQ ++F +A+    ++ C NI +++L  W++C +  R
Sbjct:  392 STAYIIVQAVPQFTVVPQDRNVFEGHTVDFHCEAQGNPKPVIAWTKGGNQLSVDRRHQVLSSGTLRILRVALHDQGQYECQAVNIVGSKSTAAQLIVQTRVTPVFATVPNDMTVEVGTDVQIPCSSQGDPLPIITW---NKDGIQVTESGKFHISPHGYLAIRDAGLADQGRYECVARNPIGYSSVSMVLSVL--------------VPEVSRTGDPFVATSIIEAIATVDRAINSTRTHLFD-SRPRSPGDLLALFRYPRDPYTVEQARAAEIFERTLQLIQDHVQSGLMVDLNGTSYH-----YNDLVSPQYLNMIANLSGCATHRRINNCSN-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNLPRG-ISGRIYNGFPLPLPRLVSTTLIGTHTITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQDCSVVCTNDAPCFPIMVPPNDPRVRNNARCMSMVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSDHESNEIRDSASHRGLLKQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDVGMKMLGEYKSYDPNVNAGILNEFATAAFRFGHTLINPILYRLDEKFEPIPQGHVPLHRAFFSPFRIVNEGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAALNVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPALMVEDLIPGSRLGPTLMCLLTTQFRNIRDGDRFWYENPGVFTAAQLTQIKQTSLARVLCDNGDNITKVQHDLFRVAEFPHGYVSCKNIAKMDLRVWQDCCEDCR 1288          

Query:  190 IIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSIS---ASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            +     L  +++      C  +C C   TV C     + +P +     T L L  N I  I    FK  K+L  + L+ N+I  +   A      L+ LYL  N IE L  + F+      +L    N     +P +  +L ++KRL L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  +GIY C A N  G +     + +    P    ++++ P +     G  V   C A G P P +T  W + ++  L ++ +  I     L I+N+ + +  G Y C+A++   +   +A I +
Sbjct:   11 LYLTAGLLVVALPQLSHSCPSRCLCFRTTVRCMHLMLESVPAVP-PHTTILDLRFNRIKDIQTGAFKHLKNLNTLLLNNNQIKRIPSEAFKDLENLKYLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSVSTITPSELNCER--------PRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLL--NDGTLMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRYYGTPATPTFVIQ-PQNTEVLVGESVTLECSATGQPHPRVT--WTRGDRTPLPSDPRINITPSGGLYIQNVNQDDA-GEYTCFATNSVETIHSTAYIIV 398          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLY--WRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR--PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            S ++   +  P+F   PQD  V  G  + F C+ +   +  + W    N  + +  +    +  L I  V    +G Y C A N  GS S +A+L +     P     P  ++ E G+ V+  C + G P+P ITW     + +++   GK+ +  +  +         +GRY C A +  G + VS V++++              +P  ++  +  +   I +A + ++ A   T   L D +R RS  D+ +LFR P     +E A+A++++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG N P G  +G++Y+G+  P  RLVS+ L+  H ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND+PCFPI+ PP DPRV+    C+   RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   E+ E+RD     G L+ G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP + G  G+K LG+Y  Y+  V++ I + FATAA RFGHTLINPILYRLDE FE IP+G++PLH+AFF+P R++ +GGIDP+LRGL  + +K   + Q++N EL EKLF+MAH VALDL ALN+QRGRDHG+  Y+ +R FC +   +TFDD   EI + ++REK++++YG P N+DLF   ++E  + G  +GPTL CLL  QF+ +RDGDRFWYE+   F  AQL+QIKQ +LAR+LCDN DNI++VQ ++F +A+    ++ C NI +++L  W++C +  R
Sbjct:  482 STAYIIVQAVPQFTVVPQDRNVFEGHTVDFHCEAQGNPKPVIAWTKGGNQLSVDRRHQVLSSGTLRILRVALHDQGQYECQAVNIVGSKSTAAQLIVQTRVTPVFATVPNDMTVEVGTDVQIPCSSQGDPLPIITW---NKDGIQVTESGKFHISPHGYLAIRDAGLADQGRYECVARNPIGYSSVSMVLSVL--------------VPEVSRTGDPFVATSIIEAIATVDRAINSTRTHLFD-SRPRSPGDLLALFRYPRDPYTVEQARAAEIFERTLQLIQDHVQSGLMVDLNGTSYH-----YNDLVSPQYLNMIANLSGCATHRRINNCSN-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNLPRG-ISGRIYNGFPLPLPRLVSTTLIGTHTITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQDCSVVCTNDAPCFPIMVPPNDPRVRNNARCMSMVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSDHESNEIRDSASHRGLLKQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDVGMKMLGEYKSYDPNVNAGILNEFATAAFRFGHTLINPILYRLDEKFEPIPQGHVPLHRAFFSPFRIVNEGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAALNVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPALMVEDLIPGSRLGPTLMCLLTTQFRNIRDGDRFWYENPGVFTAAQLTQIKQTSLARVLCDNGDNITKVQHDLFRVAEFPHGYVSCKNIAKMDLRVWQDCCEDCR 1378          

Query:  142 SPNCFQFD*IMNFFIV---IIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGN------------------------SISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSIS---ASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            SP CF +  +M        +     L  +++      C  +C C   TV C     + +P +     T L L  N                         I +I +  FK+ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L  + F+      +L    N     +P +  +L ++KRL L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  +GIY C A N  G +     + +    P    ++++ P +     G  V   C A G P P +T  W + ++  L ++ +  I     L I+N+ + +  G Y C+A++   +   +A I +
Sbjct:   58 SPECFPWLLMMMMAGAGSWLYLTAGLLVVALPQLSHSCPSRCLCFRTTVRCMHLMLESVPAVP-PHTTILDLRFNRIKDIQTGAFKHLKNLNTLLLNNNQIKRIPSEAFKDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSVSTITPSELNCER--------PRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLL--NDGTLMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRYYGTPATPTFVIQ-PQNTEVLVGESVTLECSATGQPHPRVT--WTRGDRTPLPSDPRINITPSGGLYIQNVNQDDA-GEYTCFATNSVETIHSTAYIIV 488          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLY--WRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP--CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            S ++   +  P+F   PQD  V  G  + F C+ +   +  + W    N  + +  +    +  L I  V    +G Y C A N  GS S +A+L +     P     P  ++ E G+ V+  C + G P+P ITW     + +++   GK+ +  +  +         +GRY C A +  G + VS V++++              +P  ++  +  +   I +A + ++ A   T   L D +R RS  D+ +LFR P     +E A+A++++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG N P G  +G++Y+G+  P  RLVS+ L+  H ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND+PCFPI+ PP DPRV+    C+   RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   E+ E+RD     G L+ G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP + G  G+K LG+Y  Y+  V++ I + FATAA RFGHTLINPILYRLDE FE IP+G++PLH+AFF+P R++ +GGIDP+LRGL  + +K   + Q++N EL EKLF+MAH VALDL ALN+QRGRDHG+  Y+ +R FC +   +TFDD   EI + ++REK++++YG P N+DLF   ++E  + G  +GPTL CLL  QF+ +RDGDRFWYE+   F  AQL+QIKQ +LAR+LCDN DNI++VQ ++F +A+    ++ C NI +++L  W++C +  R
Sbjct:  249 STAYIIVQAVPQFTVVPQDRNVFEGHTVDFHCEAQGNPKPVIAWTKGGNQLSVDRRHQVLSSGTLRILRVALHDQGQYECQAVNIVGSKSTAAQLIVQTRVTPVFATVPNDMTVEVGTDVQIPCSSQGDPLPIITW---NKDGIQVTESGKFHISPHGYLAIRDAGLADQGRYECVARNPIGYSSVSMVLSVL--------------VPEVSRTGDPFVATSIIEAIATVDRAINSTRTHLFD-SRPRSPGDLLALFRYPRDPYTVEQARAAEIFERTLQLIQDHVQSGLMVDLNGTSYH-----YNDLVSPQYLNMIANLSGCATHRRINNCSN-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNLPRG-ISGRIYNGFPLPLPRLVSTTLIGTHTITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQDCSVVCTNDAPCFPIMVPPNDPRVRNNARCMSMVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSDHESNEIRDSASHRGLLKQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDVGMKMLGEYKSYDPNVNAGILNEFATAAFRFGHTLINPILYRLDEKFEPIPQGHVPLHRAFFSPFRIVNEGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAALNVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPALMVEDLIPGSRLGPTLMCLLTTQFRNIRDGDRFWYENPGVFTAAQLTQIKQTSLARVLCDNGDNITKVQHDLFRVAEFPHGYVSCKNIAKMDLRVWQDCCEDCR 1145          

Query:  634 LYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISA---SAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  +GIY C A N  G +     + +    P    ++++ P +     G  V   C A G P P +T  W + ++  L ++ +  I     L I+N+ + +  G Y C+A++   +   +A I +
Sbjct:   15 LDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSVSTITPSELNCER--------PRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLL--NDGTLMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRYYGTPATPTFVIQ-PQNTEVLVGESVTLECSATGQPHPRVT--WTRGDRTPLPSDPRINITPSGGLYIQNVNQDDA-GEYTCFATNSVETIHSTAYIIV 255          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLY--WRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR--PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            S ++   +  P+F   PQD  V  G  + F C+ +   +  + W    N  + +  +    +  L I  V    +G Y C A N  GS S +A+L +     P     P  ++ E G+ V+  C + G P+P ITW     + +++   GK+ +  +  +         +GRY C A +  G + VS V++++              +P  ++  +  +   I +A + ++ A   T   L D +R RS  D+ +LFR P     +E A+A++++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG N P G  +G++Y+G+  P  RLVS+ L+  H ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND+PCFPI+ PP DPRV+    C+   RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   E+ E+RD     G L+ G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP + G  G+K LG+Y  Y+  V++ I + FATAA RFGHTLINPILYRLDE FE IP+G++PLH+AFF+P R++ +GGIDP+LRGL  + +K   + Q++N EL EKLF+MAH VALDL ALN+QRGRDHG+  Y+ +R FC +   +TFDD   EI + ++REK++++YG P N+DLF   ++E  + G  +GPTL CLL  QF+ +RDGDRFWYE+   F  AQL+QIKQ +LAR+LCDN DNI++VQ ++F +A+    ++ C NI +++L  W++C +  R
Sbjct:  421 STAYIIVQAVPQFTVVPQDRNVFEGHTVDFHCEAQGNPKPVIAWTKGGNQLSVDRRHQVLSSGTLRILRVALHDQGQYECQAVNIVGSKSTAAQLIVQTRVTPVFATVPNDMTVEVGTDVQIPCSSQGDPLPIITW---NKDGIQVTESGKFHISPHGYLAIRDAGLADQGRYECVARNPIGYSSVSMVLSVL--------------VPEVSRTGDPFVATSIIEAIATVDRAINSTRTHLFD-SRPRSPGDLLALFRYPRDPYTVEQARAAEIFERTLQLIQDHVQSGLMVDLNGTSYH-----YNDLVSPQYLNMIANLSGCATHRRINNCSN-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNLPRG-ISGRIYNGFPLPLPRLVSTTLIGTHTITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQDCSVVCTNDAPCFPIMVPPNDPRVRNNARCMSMVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSDHESNEIRDSASHRGLLKQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDVGMKMLGEYKSYDPNVNAGILNEFATAAFRFGHTLINPILYRLDEKFEPIPQGHVPLHRAFFSPFRIVNEGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAALNVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPALMVEDLIPGSRLGPTLMCLLTTQFRNIRDGDRFWYENPGVFTAAQLTQIKQTSLARVLCDNGDNITKVQHDLFRVAEFPHGYVSCKNIAKMDLRVWQDCCEDCR 1317          

Query:  190 IIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGN------------------------SISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSIS---ASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            +     L  +++      C  +C C   TV C     + +P +     T L L  N                         I +I +  FK+ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L  + F+      +L    N     +P +  +L ++KRL L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  +GIY C A N  G +     + +    P    ++++ P +     G  V   C A G P P +T  W + ++  L ++ +  I     L I+N+ + +  G Y C+A++   +   +A I +
Sbjct:   16 LYLTAGLLVVALPQLSHSCPSRCLCFRTTVRCMHLMLESVPAVP-PHTTILDLRFNRIKDIQTGAFKHLKNLNTLLLNNNQIKRIPSEAFKDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSVSTITPSELNCER--------PRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLL--NDGTLMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRYYGTPATPTFVIQ-PQNTEVLVGESVTLECSATGQPHPRVT--WTRGDRTPLPSDPRINITPSGGLYIQNVNQDDA-GEYTCFATNSVETIHSTAYIIV 427          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP--CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQ   V  G  + F C  +   +  + W    +  + +   L   +  L I  V    +G Y C A N  GS    A L + P   P     P+ ++ E G+ V+  C + G P P ITW     + V++   GK+ +     +  N   +   GRY C A +  G A VS V+++               +P  ++  +  +   I +A + ++ A   T   L D +R RS +D+ +LFR P     +  A+A +++E+ L  +   ++    V LN T+ +     +  L++P+ L++I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG NTP G  + + Y+G+  P  RLVS+ L+    ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND PCF ++ PP DPRV+    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA  +RDL    G LR G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD +Y+E+RKIVGA +QHITY  WLP +LG  G+K LG+Y GY+  V++ I + FATAA RFGHTLINP+LYRLDENFE IP+G++PLHKAFF+P R++ +GGIDP+LRGLF +  K     Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+  Y+ +R +C +  A TF+D   EI S  IREK++++YG   N+DLF   ++E  V G  +GPTL CLL  QF+RLRDGDR WYE+   F PAQL+Q+KQ +LARILCDNSDNI+RVQ++VF +A+    +  C +IPR++L  W++C +  R
Sbjct:  420 ATAFIIVQALPQFTVTPQSRVVIEGQTVDFQCAAKGHPQPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDMTVEVGTNVQLPCSSQGEPEPAITW---NKDGVQVTESGKFHISPEGFLTINDVGTADAGRYECVARNTIGYASVSMVLSV--------------NVPDVSRNGDPYVATSIVEAIATVDRAINSTRTHLFD-SRPRSPNDLLALFRYPRDPYTVGQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYH-----YNDLVSPQYLSLIANLSGCTAHRRVNNCSD-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKAVYENGFNTPRGINSQRQYNGHVLPMPRLVSTTLIGTEVITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSSVCSNDPPCFSVMIPPNDPRVRSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTDHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGEVGMKMLGEYRGYDPSVNAGIFNAFATAAFRFGHTLINPLLYRLDENFEPIPQGHVPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPALMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLWYENPGVFSPAQLTQLKQTSLARILCDNSDNITRVQQDVFRVAEFPHGYSSCEDIPRVDLRVWQDCCEDCR 1317          

Query:  223 VSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSL---------PG---------------NSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKG-SISASAKLK-IAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
             S  G  C  +C C   TV C     + +P +   + + L L         PG               N I KI    F++ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L  + F       +L    N     +P +  +L ++KRL L  N L+C CE+ + A  L+   + G     + C+ P  ++ + +  +   EL C          P+    PQDA V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  EG+Y C A N  G + +    L+ +    +P  V  P +     G  V   C A G+P+P+IT  W + ++  L  + +  I     L I+N+ +S+  G Y C+AS+   S   +A I +
Sbjct:   26 ASKQGAGCPSRCLCFRTTVRCMHLLLEAVPAVA-PQTSILDLRFNRIREIQPGAFRRLRSLNTLLLNNNQIKKIPNGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPESFQHLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKTYAQSGNAQAAATCEYPRRIQGRSVATITPEELNCER--------PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLL--DDGTLMIQNTQEADEGVYQCMAKNVAGEAKTQEVTLRYLGSPARPTFVIQPQNTEVLVGESVTLECSATGHPLPQIT--WTRGDRTPLPIDPRVNITPSGGLYIQNVAQSD-SGEYTCFASNSVDSIHATAFIIV 426          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP--CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQ   V  G  + F C  +   +  + W    +  + +   L   +  L I  V    +G Y C A N  GS    A L + P   P     P+ ++ E G+ V+  C + G P P ITW     + V++   GK+ +     +  N   +   GRY C A +  G A VS V+++               +P  ++  +  +   I +A + ++ A   T   L D +R RS +D+ +LFR P     +  A+A +++E+ L  +   ++    V LN T+ +     +  L++P+ L++I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG NTP G  + + Y+G+  P  RLVS+ L+    ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND PCF ++ PP DPRV+    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA  +RDL    G LR G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD +Y+E+RKIVGA +QHITY  WLP +LG  G+K LG+Y GY+  V++ I + FATAA RFGHTLINP+LYRLDENFE IP+G++PLHKAFF+P R++ +GGIDP+LRGLF +  K     Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+  Y+ +R +C +  A TF+D   EI S  IREK++++YG   N+DLF   ++E  V G  +GPTL CLL  QF+RLRDGDR WYE+   F PAQL+Q+KQ +LARILCDNSDNI+RVQ++VF +A+    +  C +IPR++L  W++C +  R
Sbjct:  240 ATAFIIVQALPQFTVTPQSRVVIEGQTVDFQCAAKGHPQPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDMTVEVGTNVQLPCSSQGEPEPAITW---NKDGVQVTESGKFHISPEGFLTINDVGTADAGRYECVARNTIGYASVSMVLSV--------------NVPDVSRNGDPYVATSIVEAIATVDRAINSTRTHLFD-SRPRSPNDLLALFRYPRDPYTVGQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYH-----YNDLVSPQYLSLIANLSGCTAHRRVNNCSD-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKAVYENGFNTPRGINSQRQYNGHVLPMPRLVSTTLIGTEVITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSSVCSNDPPCFSVMIPPNDPRVRSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTDHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGEVGMKMLGEYRGYDPSVNAGIFNAFATAAFRFGHTLINPLLYRLDENFEPIPQGHVPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPALMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLWYENPGVFSPAQLTQLKQTSLARILCDNSDNITRVQQDVFRVAEFPHGYSSCEDIPRVDLRVWQDCCEDCR 1137          

Query:  619 VKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSI-SASAKLK-IAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            +KRL L  N L+C CE+ + A  L+   + G     + C+ P  ++ + +  +   EL C          P+    PQDA V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  EG+Y C A N  G   +    L+ +    +P  V  P +     G  V   C A G+P+P+IT  W + ++  L  + +  I     L I+N+ +S+  G Y C+AS+   S   +A I +
Sbjct:    1 MKRLRLDSNALHCDCEILWLADLLKTYAQSGNAQAAATCEYPRRIQGRSVATITPEELNCER--------PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLL--DDGTLMIQNTQEADEGVYQCMAKNVAGEAKTQEVTLRYLGSPARPTFVIQPQNTEVLVGESVTLECSATGHPLPQIT--WTRGDRTPLPIDPRVNITPSGGLYIQNVAQSD-SGEYTCFASNSVDSIHATAFIIV 246          

Query: 1330 AKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRS--DIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLR--AHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV--QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKR-LGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFE-TIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWK 3513
            A V A+ TLI     L  + E +   S + ++   L + I +A+  ++ A+  T + +    R  S S  D+ + F+QP  A   + +A+D     L    G+L E      L        + T +LT  QL ++SQ SGC    +   CS       KYR+I G+CNN  +P  G++     R +  EYE+  + P GWT GK  +G+  P  R VS++++R  + K+T D   + M MQWGQF+DHDLDF+P   +   FS G+ C +TC    PCFPI  P  DPR+  QR CI F RS   C   ++ +       R Q+N +TSF+D S VY S+   A  LR+ T   G L        N R LLPF+   +  C +    A +PCF AGD R++E   L  +HT+++REHNRL+ ELR LN HW+GDK+Y E+RKIVGAM+Q ITY  +LP+VLG   I+R LG Y GY   VD  +++VF T A RFGHT++ P ++RLD  +  + P  ++PL   FFA  R++ +GGIDPILRGL A  +K  + D ++  EL +KLF     + LDL ALN+QR RDHGL  YN+WR FCG+ +       S  + + ++  K  ++Y  P N+D++ GA+ E  + G  VGP L+CL  +QF+R RDGDRFW++    F   Q   +++++L+RI+CDN+  I+ V R++F        F+ CS IP+LNL  W+
Sbjct:    7 ALVGALATLI-----LTQHAEGTAPASPSPVEISVLRDCIAEAKLLVDTAYNHTQKSIMQRLRSGSASPMDLLAYFKQPVAATRRVVQAADYMHVAL----GLLEER-----LQPRGSRPFNATDVLTEPQLRLLSQASGCALQDQAERCS------NKYRTITGRCNNKKHPWLGASNQALARWLPAEYEDHRSLPFGWTPGKRRNGFLLPLVRDVSNQIVRFPSKKLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFSMGVDCEKTCAQLPPCFPIKIPRNDPRIKNQRDCIPFFRSAPACPQNRNKV-------RNQINALTSFVDASMVYGSEVTLALRLRNRTNFLGLLATNQRFQDNGRALLPFDNLHEDPCLLTNRSARIPCFLAGDTRSSETPKLTALHTLFVREHNRLAAELRRLNPHWSGDKLYNEARKIVGAMVQIITYRDFLPLVLGRARIRRTLGPYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSVFFASWRIIHEGGIDPILRGLMATPAKLNRQDSMLVDELRDKLFQQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLRLYKTPDNIDIWVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKWGVFTKRQRKALRRISLSRIVCDNT-GITTVSRDIFRANIYPQGFVSCSRIPKLNLSAWR 714          

Query: 1417 KLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLF--RQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLR--AHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV--QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKR-LGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFE-TIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKS-KLEFIDCSNIPRLNLIPWKE 3516
            +++N  +   +++A+  ++ A+K+  E ++   +  S S  + LF  +QP        +A+D     LD L         K  L   +    + T +LTP QL ++S  SGC      + C      + KYR+I G CNN  +P  G++   F R +  EYE+G++ P GWT G   +G+  P AR VS+ ++R    ++T D   + M MQWGQFLDHD+  TP  A+   F  GL C  +C+   PCFP+  PP DPR+  Q+ CI F RS   C     +I       R Q+N +TSF+D S VY S+   A +LR+LT   G L +      N R L+PF+      C +    A +PCF AGD R++E   L  MHT+++REHNRL+ +L+ LN  WNG+K+Y E+RKIVGAM+Q ITY  +LP+VLG   +K+ L QY  YND VD  I++VF T A R+GHTLI P ++RL+  +  T P   +PL K FFA  RV+ +GGIDPILRGL A  +K  + +Q++  E+ E+LF     + LDL ALN+QR RDHGL  YN+WR FCG+ +  T  +    + + E+  K+   YG P N+D++ G V E     G VG  L+CL+  QF++LRDGDRFW+E+   F   Q   +  ++L RI+CDN+  I+ V +N  FM+ +   +F+ C+ +P+LNL  WKE
Sbjct:   30 EVENSVVLSCMEEAKQLVDRAYKERRESIKRSLQSGSASPTELLFYFKQPVAGTRTAVRAADYLHVALDLL---------KRKLQPLWPRPFNVTDVLTPAQLNLLSVSSGCAYQDVRVTCPP----NDKYRTITGHCNNRRSPTLGASNRAFVRWLPAEYEDGVSMPFGWTPGVNRNGFKVPLARQVSNAIVRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFFTGLNCETSCLQQPPCFPLKIPPNDPRIKNQKDCIPFFRSCPACTRNNITI-------RNQINALTSFVDASGVYGSEDPLARKLRNLTNQLGLLAINTRFQDNGRALMPFDSLHDDPCLLTNRSARIPCFLAGDMRSSEMPELTSMHTLFVREHNRLATQLKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKYLPQYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLNNQYRPTGPNPRVPLSKVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIVVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDGDRFWWENPGVFSKQQRQALASISLPRIICDNT-GITTVSKNNIFMSNTYPRDFVSCNTLPKLNLTSWKE 717          

Query: 1417 KLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLF--RQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLR--AHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV--QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKR-LGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFE-TIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKS-KLEFIDCSNIPRLNLIPWKE 3516
            +++N  +   +++A+  ++ A+K+  E ++   +  S S  + LF  +QP        +A+D     LD L         K  L   +    + T +LTP QL ++S  SGC      + C      + KYR+I G CNN  +P  G++   F R +  EYE+G++ P GWT G   +G+  P AR VS+ ++R    ++T D   + M MQWGQFLDHD+  TP  A+   F  GL C  +C+   PCFP+  PP DPR+  Q+ CI F RS   C     +I       R Q+N +TSF+D S VY S+   A +LR+LT   G L +      N R L+PF+      C +    A +PCF AGD R++E   L  MHT+++REHNRL+ +L+ LN  WNG+K+Y E+RKIVGAM+Q ITY  +LP+VLG   +K+ L QY  YND VD  I++VF T A R+GHTLI P ++RL+  +  T P   +PL K FFA  RV+ +GGIDPILRGL A  +K  + +Q++  E+ E+LF     + LDL ALN+QR RDHGL  YN+WR FCG+ +  T  +    + + E+  K+   YG P N+D++ G V E     G VG  L+CL+  QF++LRDGDRFW+E+   F   Q   +  ++L RI+CDN+  I+ V +N  FM+ +   +F+ C+ +P+LNL  WKE
Sbjct:   30 EVENSVVLSCMEEAKQLVDRAYKERRESIKRSLQSGSASPTELLFYFKQPVAGTRTAVRAADYLHVALDLL---------KRKLQPLWPRPFNVTDVLTPAQLNLLSVSSGCAYQDVRVTCPP----NDKYRTITGHCNNRRSPTLGASNRAFVRWLPAEYEDGVSMPFGWTPGVNRNGFKVPLARQVSNAIVRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFFTGLNCETSCLQQPPCFPLKIPPNDPRIKNQKDCIPFFRSCPACTRNNITI-------RNQINALTSFVDASGVYGSEDPLARKLRNLTNQLGLLAINTRFQDNGRALMPFDSLHDDPCLLTNRSARIPCFLAGDMRSSEMPELTSMHTLFVREHNRLATQLKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKYLPQYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLNNQYRPTGPNPRVPLSKVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIVVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDGDRFWWENPGVFSKQQRQALASISLPRIICDNT-GITTVSKNNIFMSNTYPRDFVSCNTLPKLNLTSWKE 717          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP--CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQ   V  G  + F C  +   +  + W    +  + +   L   +  L I  V    +G Y C A N  GS    A L + P   P     P+ ++ E G+ V+  C + G P P ITW     + V++   GK+ +     +  N   +   GRY C A +  G A VS V+++               +P  ++  +  +   I +A + ++ A   T   L D +R RS +D+ +LFR P     +  A+A +++E+ L  +   ++    V LN T+ +     +  L++P+ L++I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG NTP G  + + Y+G+  P  RLVS+ L+    ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND PCF ++ PP DPRV+    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA  +RDL    G LR G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD +Y+E+RKIVGA +QHITY  WLP +LG  G+K LG+Y GY+  V++ I + FATAA RFGHTLINP+LYRLDENFE IP+G++PLHKAFF+P R++ +GGIDP+LRGLF +  K     Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+  Y+ +R +C +  A TF+D   EI S  IREK++++YG   N+DLF   ++E  V G  +GPTL CLL  QF+RLRDGDR WYE+   F PAQL+Q+KQ +LARILCDNSDNI+RVQ++VF +A+    +  C +IPR++L  W++C +  R
Sbjct:  420 ATAFIIVQALPQFTVTPQSRVVIEGQTVDFQCAAKGHPQPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDMTVEVGTNVQLPCSSQGEPEPAITW---NKDGVQVTESGKFHISPEGFLTINDVGTADAGRYECVARNTIGYASVSMVLSV--------------NVPDVSRNGDPYVATSIVEAIATVDRAINSTRTHLFD-SRPRSPNDLLALFRYPRDPYTVGQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYH-----YNDLVSPQYLSLIANLSGCTAHRRVNNCSD-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKAVYENGFNTPRGINSQRQYNGHVLPMPRLVSTTLIGTEVITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSSVCSNDPPCFSVMIPPNDPRVRSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTDHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHETRKIVGAEIQHITYRHWLPKILGEVGMKMLGEYRGYDPSVNAGIFNAFATAAFRFGHTLINPLLYRLDENFEPIPQGHVPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRIPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIKSPVIREKLQRLYGSTLNIDLFPALMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLWYENPGVFSPAQLTQLKQTSLARILCDNSDNITRVQQDVFRVAEFPHGYSSCEDIPRVDLRVWQDCCEDCR 1317          

Query:  223 VSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSL---------PG---------------NSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKG-SISASAKLK-IAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
             S  G  C  +C C   TV C     + +P +   + + L L         PG               N I KI    F++ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L  + F       +L    N     +P +  +L ++KRL L  N L+C CE+ + A  L+   + G     + C+ P  ++ + +  +   EL C          P+    PQDA V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  EG+Y C A N  G + +    L+ +    +P  V  P +     G  V   C A G+P+P+IT  W + ++  L  + +  I     L I+N+ +S+  G Y C+AS+   S   +A I +
Sbjct:   26 ASKQGAGCPSRCLCFRTTVRCMHLLLEAVPAVA-PQTSILDLRFNRIREIQPGAFRRLRSLNTLLLNNNQIKKIPNGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPESFQHLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKTYAQSGNAQAAATCEYPRRIQGRSVATITPEELNCER--------PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLL--DDGTLMIQNTQEADEGVYQCMAKNVAGEAKTQEVTLRYLGSPARPTFVIQPQNTEVLVGESVTLECSATGHPLPQIT--WTRGDRTPLPIDPRVNITPSGGLYIQNVAQSD-SGEYTCFASNSVDSIHATAFIIV 426          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP--CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQD  V  G  + F C+ +      + W    +  + +   L   +  L I  V    +G Y C A N  GS    A L + P   P     P+  + E G+ V+  C + G P P ITW     + V++   GK+ +     +  N       GRY C A +  GSA VS V+++               +P  ++  +  +   I +A + ++ A   T   L D +R RS +D+ +LFR P     +E A+A +++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG NTP G    +LY+G++ P  RLVS+ L+    +TPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND PCF ++ PP D R +    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA  +RDL    G LR G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IYYE+RKIVGA +QHITY  WLP +LG  G++ LG+Y GY+  +++ I + FATAA RFGHTL+NP+LYRLDENF+ I + +LPLHKAFF+P R++ +GGIDP+LRGLF +  K     Q++N EL E+LF+MAH VALDL A+NIQRGRDHG+  Y+ +R +C +  A TF+D   EI + EIREK++++YG   N+DLF   V+E  V G  +GPTL CLL  QFKRLRDGDR WYE+   F PAQL+QIKQ +LARILCDN+DNI+RVQ +VF +A+    +  C  IPR++L  W++C +  R
Sbjct:  423 ATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW---NKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV--------------NVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFD-SRPRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYH-----YNDLVSPQYLNLIANLSGCTAHRRVNNCSD-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQDCCEDCR 1320          

Query:  235 GQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSL---------PG---------------NSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQW----LFIKEVHEFHEGIYICTASNNKGSI-SASAKLK-IAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            G  C  +C C   TV C     + +P +   + + L L         PG               N I +I +  F++ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L    F       +L    N     +P +   L ++KRL L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +   EL C          P+    PQDA V  G+ + F C+ E   + ++ W    N+ +  +    N      L I+   E  +GIY C A N  G + +    L+      +P  V  P +     G  V   C A G+P P I+  W + ++  L  + +  I     L I+N+ + +  G Y C A++   S   +A I +
Sbjct:   33 GAGCPSRCLCFRTTVRCMHLLLEAVPAVA-PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCER--------PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRIS--WTRGDRTPLPVDPRVNITPSGGLYIQNVVQGD-SGEYACSATNNIDSVHATAFIIV 429          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLY--WRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR--PCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            S ++   +  P+F   PQD  V  G  + F C+ +   +  + W    N  + +  +    +  L I  V    +G Y C A N  GS S +A+L +     P     P  ++ E G+ V+  C + G P+P ITW     + +++   GK+ +  +  +         +GRY C A +  G + VS V++++              +P  ++  +  +   I +A + ++ A   T   L D +R RS  D+ +LFR P     +E A+A++++E+ L  +   ++    V LN T+ +     +  L++P+ L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+ F RL+K  YENG N P G  +G++Y+G+  P  RLVS+ L+  H ITPD   + M+MQWGQFLDHDLD T V  S +RFSDG  C+  C ND+PCFPI+ PP DPRV+    C+   RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   E+ E+RD     G L+ G V  S K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP + G  G+K LG+Y  Y+  V++ I + FATAA RFGHTLINPILYRLDE FE IP+G++PLH+AFF+P R++ +GGIDP+LRGL  + +K   + Q++N EL EKLF+MAH VALDL ALN+QRGRDHG+  Y+ +R FC +   +TFDD   EI + ++REK++++YG P N+DLF   ++E  + G  +GPTL CLL  QF+ +RDGDRFWYE+   F  AQL+QIKQ +LAR+LCDN DNI++VQ ++F +A+    ++ C NI +++L  W++C +  R
Sbjct:  413 STAYIIVQAVPQFTVVPQDRNVFEGHTVDFHCEAQGNPKPVIAWTKGGNQLSVDRRHQVLSSGTLRILRVALHDQGQYECQAVNIVGSKSTAAQLIVQTRVTPVFATVPNDMTVEVGTDVQIPCSSQGDPLPIITW---NKDGIQVTESGKFHISPHGYLAIRDAGLADQGRYECVARNPIGYSSVSMVLSVL--------------VPEVSRTGDPFVATSIIEAIATVDRAINSTRTHLFD-SRPRSPGDLLALFRYPRDPYTVEQARAAEIFERTLQLIQDHVQSGLMVDLNGTSYH-----YNDLVSPQYLNMIANLSGCATHRRINNCSN-MCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNLPRG-ISGRIYNGFPLPLPRLVSTTLIGTHTITPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQDCSVVCTNDAPCFPIMVPPNDPRVRNNARCMSMVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSDHESNEIRDSASHRGLLKQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLRLNPHWDGDTIYHETRKIVGAQMQHITYSHWLPKIFGDVGMKMLGEYKSYDPNVNAGILNEFATAAFRFGHTLINPILYRLDEKFEPIPQGHVPLHRAFFSPFRIVNEGGIDPLLRGLIGVAAKMRVTSQLLNTELTEKLFSMAHAVALDLAALNVQRGRDHGIPPYHDFRVFCNLSTVQTFDDLRNEIKNPDVREKLKRLYGSPLNIDLFPALMVEDLIPGSRLGPTLMCLLTTQFRNIRDGDRFWYENPGVFTAAQLTQIKQTSLARVLCDNGDNITKVQHDLFRVAEFPHGYVSCKNIAKMDLRVWQDCCEDCR 1309          

Query:  190 IIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGN------------------------SISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSIS---ASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            +     L  +++      C  +C C   TV C     + +P +     T L L  N                         I +I +  FK+ ++L ++ L  N+I  ++  A  G   LE LYL  N IE L  + F+      +L    N     +P +  +L ++KRL L  N L+C CE+ + A  L+     G     + C+ P  ++ + +  +  +EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      D+  N L   +  L I+   E  +GIY C A N  G +     + +    P    ++++ P +     G  V   C A G P P +T  W + ++  L ++ +  I     L I+N+ + +  G Y C+A++   +   +A I +
Sbjct:    8 LYLTAGLLVVALPQLSHSCPSRCLCFRTTVRCMHLMLESVPAVP-PHTTILDLRFNRIKDIQTGAFKHLKNLNTLLLNNNQIKRIPSEAFKDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLEPESFNYLPKLERLFLHNNRITHLVPGTFSQLESMKRLRLDSNALHCDCEILWLADLLKIYSESGNAQAAATCEYPRRLQGRSVSTITPSELNCER--------PRITSEPQDVDVTFGNTVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLL--NDGTLMIQNTKETDQGIYQCMAKNVAGEVKTHEVTLRYYGTPATPTFVIQ-PQNTEVLVGESVTLECSATGQPHPRVT--WTRGDRTPLPSDPRINITPSGGLYIQNVNQDDA-GEYTCFATNSVETIHSTAYIIV 419          

Query:  796 FEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNS----LYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKP-YIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQV---RLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKL---RDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQ-RPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNI-RGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE---CYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQC-SSNISNL----EERIKSLED 3684
             E  EL P+ +  PQ   + +G      C  +      ++W         N+    L   N  L +    + H G+Y CTA N  G  S  A +K+  +Q P  +   P+++ A  G+ +E  C+A   P   +   W    ++    ++   KY I    +L ++N+T  +  GRY C   +  G A  SA++T IR+  +L   +   ++                +A  +I++A   T + L   R      +  ++  +FR P+  A +LA+A+++YE+ L ++   ++E     NLT   EE  +F  LL+ E L ++++LSGC    E  +C+  +CFH +YRSIDG CNNL +P  G++L+ F RL  P YENG + P+GWT G LY G++KPSARLVS+ L+   +ITPD  ++ MVMQWGQFLDHDLD   + + +S   DG+ C ++C    PC+PI  PP DPRV+ R CI   RS A CGSG +S+    + +REQ+NQ+TS++D S VY      A ELR+LT  EG LRVG   P  K +LPF   +  +DC+ +  +  + CF +GD R NE +GLL MHTIWMREHNR++ +L+ +N+HW+GD +Y E+RKIVGA MQHIT+  WLP+++G  G++ +G+Y GYN  ++ +I++ FATAA+RFGHT+INPIL+RL+E F+ IP+G+L LHKAFFAP R+  +GG+DP++RG  A+ +K    DQ +N EL EKLF  AH VALDL A+NIQRGRDHG+  YN +R+ C +  A+ F+D +GEI S+EIR+KM+++YGHP NVD++ G +LE +V GG VGP   CLL++QF+RLRDGDR +YE+   F P QL+QIKQ    R+LCD  DN  +V  NVF +AK +  +  C +I  +NL  W+E   C  P  +  +  +P     RS R   +   +N +  T +   S + +L    EER+  LE+
Sbjct:  452 IELKEL-PEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQAD-QPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPD-GGRYECQLKNQFGRASASALVT-IRNNVDLAPGDRYVRI-------------AFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYERTLVNIRKHVQEGD---NLTMKSEE-YEFRDLLSREHLHLVAELSGCMEHREMPNCTD-MCFHSRYRSIDGTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDHA-IPSVSSESWDGIDCKKSCEMAPPCYPIEVPPNDPRVRNRRCIDVVRSSAICGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFPRQKDMLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMMGEYQGYNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYLWQECGRCNSPPAIF-DSYIPQTYTKRSNRQKRDLGKENDEVATAESYDSPLESLYDVNEERVSGLEE 1412          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXX-----------------------XXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKS------QCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTF----NSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPAS-------------------------------------ISAEKGS-RVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C   C C E+TV C R     +P++     T L L  N I ++ AN F     L  + L+ N+++ +++ AL G   L  +YL NN +  LP  IF                                L + NN+L  LP+    +L N+KRL L GN + C C +       RR  LD Q+        C +P  ++NQ      F+ L  + F+ ++  P+F+  PQDA VA G+++  +C+V  +   ++ W     +        +    +  L I+       GIY C A N  G++  S  +++  N   + ++ P                                       I A  GS  V   C A G+P P+I W +V   Q+   T    +    +L++    +    G Y C A +  GS + +A I L
Sbjct:   26 CPAGCTCLERTVRCIRAKLSAVPKLPQDTQT-LDLRFNHIEELPANAFSGLAQLTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSL---WRRWHLDVQRQLVSISLTCAAPQMLQNQ-----GFSSLGEHHFKCAK--PQFLVAPQDAQVAAGEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEILPSGSLLIRSADTSDMGIYQCIARNEMGALR-SQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQW-FVNGRQLLQSTPSLQLQANGSLILLQPNQLSA-GTYRCEARNSLGSVQATARIEL 454          

Query:  823 FIERPQDAYVAV--GDKIRFACQVENINETKVEWHF---QFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL--ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKL 1404
            F  +P D  VA+     +   C      +  ++W     Q   +T +     N  L + + ++   G Y C A N+ GS+ A+A++++   + P I+  P S + + G      C A G P+P I W   + N V L   T    +  +N  ++      E  G Y C A + +G   V A I + RS++   L  E S L
Sbjct:  367 FTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIEL--KELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDW---QLNGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNL 562          

Query:  814 APKFIERPQDAYVAVGDKIRFACQVENINETKVEWH---FQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNN--LVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFR-QPSLAALELAKASDVYEKVLDDLTGILRENKVK---LNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV-----QRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAH-VPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGI--KRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVF-FMAKSKLEFIDCSNIPRLNLIPWKECYD 3525
            AP+F  +P+D     G +++  C+V    +  + W+    +F  +    L   N  L I    E   G Y C A N+ G +S +  L +  +  P I EGP S+S   G  V F C+A G P P+ TW +  S    ++  G+++V  +   L I NI E + EG Y C A +  G+    A +T+I  +         ++  S  ++  E L  I + A+  +  A +KT ++L + ++  + +D++ LFR      A+EL+KA ++YE+ +     ++RE+  K   LN+   +   + + ++L    +  +  LSGC     +  C+   CFH KYRS DG+CNN   P  G +L P  RL+KP YENG NTP+GW  GKLY+GY  P+ R VS +L+    ITP   LS+MVMQWGQF+DHDL  T    S   ++ G  CN TC N  PCF I   P DPRV     + PCI F RS A CGSG++S++  ++ YREQ+N +TSFLD SNVY S+ ++A ELRD   + G+LR    + + K  LPF     +DC+ + ++ + + CF AGD R NE L L   HTI++REHNR++ +L+ +N +W+G+ IY+E+RKI+GAMMQHIT+  WLP+V G +    K +G+Y GY+  +DS++++ FATAA RFGHT+INP L+RL  +F +I +G++ LHKAFF P+ V+ +GGIDP+LRGLFA   K     Q++N ELIEKLF   HEV+LDL  +NIQR RDHGL SY  +R+FC +     ++D  G I    I +K+R +YG P N+DL+ G ++E+K+  GL GPT +C++ +QF+++RDGDRFWYE    F P Q+ +IK+VTLAR+LCDN D I R+Q++VF +  K K  +  C +   ++L  W +C D
Sbjct:  313 APQFTYKPRDNSYREGSEVKVNCEVMGTPKPSITWYHNGVRFASSRKKQLGLSNNVLRIYPFLEEDSGRYTCEAVNSLGKVSHTFSLDLISSIPPNIYEGPQSVSQNIGGEVVFVCKAKGNPTPDYTWSFDGSTIGHIK--GRFMVSDDGTELXISNI-EKKDEGYYSCMAGNPVGAMSADAKLTVIGGE---------TRKSSTPQIDEELLRAIAQKARQNVESAVEKTRKQL-NQDKITNTNDLKRLFRFSTPKQAVELSKAREIYEESVR----LVREHVEKGLILNVDELHPNNVSYESVLHVTHVQALMGLSGCHTGQFKNPCTDT-CFHNKYRSFDGQCNNKNKPMNGVSLMPLRRLLKPVYENGFNTPVGWEKGKLYNGYPMPNVREVSRQLVATETITPHRKLSSMVMQWGQFVDHDLTHTVTALSRHSYATGAFCNRTCDNLDPCFNIPLSPSDPRVISESAKYPCIEFERSAAVCGSGETSLVFNRVTYREQMNALTSFLDASNVYGSNEVQAQELRDTYNNNGQLRYDITSAAGKEYLPFEKDSNMDCRRNFSEENPIRCFLAGDLRANEQLALAATHTIFVREHNRIAKKLKKMNGNWDGEVIYHETRKIIGAMMQHITFKHWLPVVFGGQEQMDKFVGKYQGYDPAIDSSVTNAFATAAFRFGHTIINPTLFRLGNDFMSIKQGHIALHKAFFTPELVLTEGGIDPLLRGLFASPLKHPMPTQLLNMELIEKLFMKGHEVSLDLAVMNIQRSRDHGLPSYTEYRQFCNLPVPARWEDMKGYIKDDMIIQKLRGLYGVPQNIDLWVGGIVEEKLENGLFGPTFACIIGEQFRKMRDGDRFWYEKDGVFTPEQMKEIKKVTLARLLCDNGDEIDRIQKDVFMYPGKEKENYGRCEDTEMMDLKAWSKCCD 1216          

Query:  244 CLPQCRCTEK--TVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENAL-----------------YGPIF------LETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISL-EKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQK-----------PYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL-ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRS 1365
            C  +C C +K  TV C   G   IP+  +  +  L L  N I  +I +  + F  L  + L+ NKI +VEEN L                 Y P        L +L LK N I+++ E+    +   L  + L++NR+++L   L E L ++    L+ N   C C +      LR++  + +K+ C +P+ +++Q ++EV+ + L C+   E S                 GD+ +  C     +   V W ++  +   +SL          + +E H+ +       N   ++ +   +  P+ +           P     P   S  +GS V+ +C   G P P ITW     N VR   +  K +   NN++       E  GRY C A +  G    +  + LI S
Sbjct:   21 CPAKCTCDKKGFTVDCSNAGLTRIPKGISSNVRSLVLRNNRIHTLIKSDLEGFPLLESLVLTHNKIKVVEENILDHLPELKRLSLSHNLLVYIPPLASESRPLASLNLKRNHIQFIDERWLLQYFPELVQIDLSHNRIQSLRTKLFENLPSLTHAHLHANPWNCDCRVTKVKALLRKVEWE-RKAYCTNPVELRHQAIDEVEESLLKCAKPEEES---------------WTGDEFKLVCTKNASSSRPVVWLYENAEVDSSSL----------DGYEIHDSVITVPRKTNVNQMTCTYDYEHVPHHRRLRQSHHSNGAPQFTYKPRDNSYREGSEVKVNCEVMGTPKPSITWY---HNGVRFASSRKKQLGLSNNVLRIYPFLEEDSGRYTCEAVNSLGKVSHTFSLDLISS 404          

Query:  184 IVIIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEI-------GNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKSQCQSPMNVKNQ---------------------------FLEEVKFNELCS-----------------------NSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASIS--AEKGSRVEFSCRAHGYPVPEITWLWVKSNQV-RLETEGKYIVRKN---------------------------------NLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSR------------NKLKNEQLYE-IIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGIL---RENKVKLNLTTAYEETLDFT--------TLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLL----------------------------RAHKITP---------------DPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLG--QYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWR-EFCGMKKA---ETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVT--LARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKEC 3519
            +  I+LG L     ST    C   C C  +++ CRR    +IP+I           L Y ++    +S++    F    D++ +DLS N+I ++E  A      L  L L+ N +  LP+ IF       +L   + N+L  +P SL++++ +K L L GN L+CGC +  FA  L        +  C +P  V  +                           F EE+   +L                         +S   S  AP+ IE P    VA G+++ F CQ   +   K+ W    N++    L+ + + L ++EVH +HEG Y C A N  G +S S  L++    KP I + P++ +   E G  +E +C A G P P + WL+  ++   RL T+G+Y+VR +                                  L I N+TE + EGRY CYA++ +GS +V++++TL R  +  + N    K  SR            +K  +E L + +I+ A+ +I+ A +KTA+ LRDP  +R+ SDI SLFRQPS AA+ELA+A++VYE  +D++T IL   R      +    Y   +DF           LT EQLAII+QLSGC +S     C +QLCFH +YRSIDG CNNL  P+ G+ALSPFYRL+ P YENG+N P+GW   KLY GY KPSARLVS RLL                            R+H  +                D + S M+MQWGQFLDHDLDFTPVDAS SRFSDGLGCNETC+ND PCFPILTPPGDPR+++ CIGF+RS ATCGSG +SI+LG+  +REQ+NQI+++LD SNVY S+  E ++LRD  YDEG LR G  TP+ K+LLPFNIRGQVDCQ DP +  VPCFKAGDHR+NENLGLL MHTIWMREHNR++DELR LN HW+GD++Y+E+RKIVGA+MQ ITY  WLP VLG  G++ +G   YPGY+  V+ TIS+ FATAA RFGHT++ PI +RL+EN+ETIPEG+L LHKAFFAPD+++ DGG+DPILRGL   G + +     +N EL E+LFAMAH++ALDL +LNIQRGRDHGL  Y S+  + CG+  +   ++F+D +  I    IRE+MR VYGHPGN+DLF G VLE  + G  +GPT +C++ DQFKRLR GDR WYES   F  AQL++I+     L+R++C+N DNI+ V  + F   K++ + + CS +P+LNL  WKEC
Sbjct:    8 VAFIWLGLLTLFCTSTCQDACPGNCVCFSQSIVCRRSTETVIPKIPAFLDGPQGGALQYFAITNTKLSRVPTEAFVGLLDIMSIDLSNNEIEVIEGGAFQDLPILAHLLLRQNQLTQLPDNIFDTLPSLEELDL-SFNQLTAIPSSLQRMVGLKSLSLRGNPLHCGCGIVDFAQLLPYWESSLDRVTCATPAQVAGKSIKELGRQYFQAFEGTRHLGYWPDEYAFPEEISRKQLIRTRTPWPLPHCPVKDLGGEVVDNVDSSNGSYEAPQIIEAPVPVMVAEGERVFFVCQATGVPRPKISWMLPTNNSQHVHLWDKRKILELREVHAYHEGTYTCIAKNRVGQVSHSVMLQLVDIVKPQITDAPSTKATVGEPGGDIELTCTARGRPRPTVDWLYTHTSSAKRLSTQGRYVVRSSAKLSTRTIQDLTYRDPLAQTDESLRLEGEEESVTLTIRNVTELDTEGRYTCYAANRAGSTRVTSLVTLKRWTDMASDNGGEDKDASRGKRVESDSAEISDKESDEDLVKRVIEKARRRIDAAIQKTADNLRDPKNRRTASDIASLFRQPSKAAVELARAAEVYEAAIDEVTQILQRQRNQSFGKDTEGPYRSDVDFDEQKRQAMGVQLTAEQLAIIAQLSGCAQSQRVEPCDRQLCFHMRYRSIDGSCNNLKYPKWGAALSPFYRLLPPVYENGVNQPVGWNPEKLYFGYPKPSARLVSYRLLADATKLQVHTQKLETFNQRIKMSLKFNNRSHDTSSLFDFPLYEKEELFDEDDSSSGMLMQWGQFLDHDLDFTPVDASTSRFSDGLGCNETCINDPPCFPILTPPGDPRIRQRCIGFARSSATCGSGSTSILLGRPQHREQLNQISAYLDASNVYGSEDFENSQLRDTLYDEGHLRGGMPTPAGKQLLPFNIRGQVDCQADPQQDFVPCFKAGDHRSNENLGLLSMHTIWMREHNRIADELRSLNPHWSGDRLYHEARKIVGALMQSITYRVWLPKVLGPRGMEMMGGETYPGYDSSVNPTISNEFATAAFRFGHTMVPPIYFRLNENWETIPEGHLLLHKAFFAPDKMLTDGGMDPILRGLLFHGIRDIIRRPSLNPELTERLFAMAHQLALDLASLNIQRGRDHGLQHYTSYAYKICGLGSSAAPDSFEDLADRIHDPAIREEMRAVYGHPGNIDLFVGGVLEDVLPGARMGPTFACIIADQFKRLRAGDRLWYESPGLFTTAQLAEIRDAGSYLSRVICENGDNITEVPLDAFIRPKNRKDLVSCSQVPKLNLALWKEC 1286          

Query:  184 IVIIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEI----GNKR---LTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKSQCQSPMNVKNQ---------------------------FLEEVKFNEL-----------------------CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPAS--ISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQV-RLETEGKYIVRKNN---------------------------------LVIENITESEVEGRYVCYASSLSGSAKVSAVITLIR-----------SKNEL-NLNEESSKLPSRNKLKNEQLYE-IIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENK---VKLNLTTAYEETLDFTTL--------LTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLL----------------------------RAHKITP---------------DPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLG--QYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWR-EFCGMKKA---ETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVT--LARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPS 3531
            +  I+ G L     +T    C   C C  ++V CRR     IP +    G+ +   L Y ++    +S+++   F    D++++DLS N+I ++EE A      L  L L+ N +E LP+ IF       +L    N+ L  +P SL++L+ +K L L GN L+CGC +  FA  L        ++ CQ+P+ V  +                           F EEV    L                          S EA E +P+ ++ P     A G+++ F+CQ     + K+ W    NDT +  L+ + + L ++EVH FH G Y C A N  G +S S  L+I    KP I + P++   S   G  +E +C A G P P + WL+  ++   RL T+ +Y VR +                                  L I N+T+ + EGRY CYA++ +GS +V++++TL++            K+E  + +EES  L    K  +E L + +I+ A+ +I+ A +KTA+ LRDP  +R+ SDI SLFRQP+ AA+ELA+A++VYE  +D++T IL++ +      +    Y   +DF           LT EQLAII+QLSGC +S     C +QLCFH +YRSIDG CNNL  P+ G+ALSPFYRL+ P YENG+N P+GW   KLY GY KPSARLVS RLL                            R+H  +                D   S M+MQWGQFLDHDLDFTPVDAS SRFSDGLGCNETC+ND PCFPI+TPPGDPR+++ C+GF+RS ATCGSG +SI+LG+  +REQ+NQI+++LD SNVY S+  E ++LRD  YDEG LR G  TP+ K+LLPFNIRGQVDCQ DP +  VPCFKAGDHR+NENLGLL MHTIWMREHNR++DELR LN HW+GD++YYE+RKIVGA+MQ ITY  WLP VLG  G++ +G   YPGY+  V+ TIS+ FATAA RFGHT++ PI +RL+EN+ETIPEG+L LHKAFFAPD+++ DGG+DP+LRGL   G + +     +N EL E+LFAMAH++ALDL +LNIQRGRDHGL  Y S+    C +  +   ++FDD +  I     REK+R VYGHPGN+DLF G VLE  + G  +GPT +C++ DQFKRLR GDR WYES   F  AQL++I+     L+R++C+N DNI+ V  + F   KS+ + + CS +P+LNL+ WKEC  PS
Sbjct:    8 VAFIWFGLLTSFHFATCQDVCPRNCVCFSQSVVCRRATMATIPRLPAFLGDSQGGALQYFAMTNTKLSRVLNESFVGLLDIMNIDLSDNEIEVIEEGAFQNLPLLAHLLLRQNRLEQLPDNIFDTLPSLEELDLSFNH-LTNIPPSLQRLVALKSLSLRGNPLHCGCGIVDFAQLLPYWESSLDRATCQTPLEVAGRSIRELGRRYLQAFEGTRHLGYWPDEYVFPEEVNRKRLIRTSTPWPLPHCLVKDLGGVVDAVETSVEAYE-SPQIVDPPIPVMAAEGERVFFSCQAIGEPKPKISWMLPTNDTQYVRLWDKRRILELREVHAFHAGTYTCIAENEAGQVSHSVVLQIVDIVKPQITDAPSTQATSGVLGGDIELTCTARGRPRPTVDWLYTHTSSAKRLSTQDRYTVRSSTKLSTHTIQDLIYRDPSAQTDESLRFEGEEESVTLTIRNVTQLDTEGRYTCYAANRAGSTRVTSLVTLVKMPSMGGDNGGEGKDETGHKSEESDDLEVSPKESDEDLVKWVIEKARRRIDAAIQKTADNLRDPKNRRTASDIASLFRQPNKAAIELARAAEVYEAAIDEVTQILQQQRNQSFGKDTEGPYRSDVDFDAQKRQAMGVQLTAEQLAIIAQLSGCAQSQRVEPCDRQLCFHMRYRSIDGSCNNLKYPKWGAALSPFYRLLPPVYENGVNQPVGWNPEKLYFGYPKPSARLVSYRLLADATKLQAHTRKLETFNQRIKMSLRFDNRSHDTSSPFDFPLYEKETLFDEDDTSSGMLMQWGQFLDHDLDFTPVDASTSRFSDGLGCNETCINDPPCFPIITPPGDPRIRQRCMGFARSSATCGSGSTSILLGRPQHREQLNQISAYLDASNVYGSEEFENSQLRDTLYDEGHLRGGIPTPAGKQLLPFNIRGQVDCQADPQQDFVPCFKAGDHRSNENLGLLSMHTIWMREHNRIADELRSLNPHWSGDRLYYEARKIVGALMQSITYRVWLPKVLGPRGMEMMGGETYPGYDSSVNPTISNEFATAAFRFGHTMVPPISFRLNENWETIPEGHLLLHKAFFAPDKLLTDGGMDPVLRGLLFHGVRDIIRRPSLNPELTERLFAMAHQLALDLASLNIQRGRDHGLQHYTSYAYTICNLGSSAAPDSFDDLADRIRDPATREKLRAVYGHPGNIDLFVGGVLEDVLPGARMGPTFACIIADQFKRLRAGDRLWYESPGLFTTAQLAEIRDAGSYLSRVICENGDNITEVPLDAFLRPKSRKDLVPCSQVPKLNLVLWKECPSPS 1289          

Query:  184 IVIIFLGSLNFLSVSTTGQECLPQ-CRCTEKTVTCRRGGFQMIPEIG-------NKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKSQCQSPMNVKNQ---------------------------FLEEVKFNELC-----------------------SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEK--GSRVEFSCRAHGYPVPEITWLWVKSNQV-RLETEGKYIVRKNN---------------------------------LVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKL------------KNEQLYE-IIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGIL---RENKVKLNLTTAYEETLDFT--------TLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLL----------------------------RAHKITP---------------DPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLG--QYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWR-EFCGMKKA---ETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVT--LARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLS-----PSRSRRSTNEFQDQNCKSKTNQCSSNISNLEERIKS 3675
            +  I+L  L     S+TGQ+  P+ C C  +++ CRR     IP+I           L Y ++    ++++    F    D++++DLS N+I ++EE A      L  L L+ N +  LP+ IF       +L   + N+L T+P+SL++L+ +K L L GN L+CGC +  FA  L        ++ C +P  V  +                           F EE+   +L                        +++   S  AP+ +E P    VA G+++ F CQ   + + K+ W    N++ +  L+ + + L ++EVH FHEG Y C A N  G +S S  L+I    KP I + P++ +     G  +E +C A G P P + WL+  ++   RL T+G+Y+VR +                                  L I N+TE + EGRY CYA++ +GS +V++++TL +  +  + N +  K  S +K              +E L + +I+ A+ +I+ A +KTA+ LRDP  +R+ SDI SLFRQPS AA+ELA+A++VYE  +D++T IL   R      +    Y   +DF           LT EQLAII+QLSGC +S     C +QLCFH +YRSIDG CNNL  P+ G+ALSPFYRL+ P YENG+N P+GW   +LY GY KPSARL S RLL                              H  +                D   S M+MQWGQFLDHDLDFTPVDAS SRFSDGLGCNETC+ND PCFPILTPPGDPR+++ CIGF+RS ATCGSG +SI+LG+  +REQ+NQI+++LD SNVY S+  E ++LRD  YDEG LR G  TP+ K+LLPFNIRGQVDCQ DP +  VPCFKAGDHR+NENLGLL MHTIWMREHNR++DELR LN HW+GD++Y+E+RKIVGA+MQ ITY  WLP VLG  G++ +G   YPGY+  V+ +IS+ FATAA RFGHT++ PI +RL+EN+E IPEG+L LHKAFFAPD+++ DGG+DPILRGL   G + V     +N EL E+LFAMAH++ALDL +LNIQRGRDHGL  Y S+    CG   +   ++FDD +  I    IRE++R VYGHPGN+DLF G VLE  + G  +GPT +C++ DQFKRLR GDR WYES   F  AQL++++     L+R++C+N DNI+ V  + F   KS+ + + CS +P+LNL  WKEC  PS  TP      +      P   RR +   +D +C++K     S ++ +E+ +++
Sbjct:    8 VAFIWLSLLTLFH-SSTGQDACPRNCVCFSQSIVCRRSTETTIPKISAFLDDPQGGALQYFAMTNTKLTRVPTEAFVGLLDVMNIDLSDNEIEVIEEGAFQDLPLLAHLLLRQNRLPQLPDNIFDTLPGLEELDL-SFNQLTTIPLSLQRLVGLKSLSLRGNPLHCGCGIVDFAQLLPYWESSLDRATCTTPAEVAGKSIKELGRQYHQAFEGTRHLGYWPDQYAFPEEISGKQLIRTRTPWPLPHCPMKDLGGEFVDETDTSMGSFEAPQIVEAPVPVMVAEGERVFFVCQATGVPKPKISWMLPTNNSQYVRLWDKRRILELREVHAFHEGTYTCIAENRVGQVSHSVMLQIVDIVKPQITDAPSTQATAGVLGGDIELTCTARGRPRPTVDWLYTHTSSAKRLSTQGRYVVRSSTKLSARTIHDLIYRDPSAQSDESLRLEGEEESLTLTIRNVTEIDTEGRYTCYAANRAGSTRVTSLVTLKKRPSMGDGNGDGDKNASDDKRGESDDPEIASKESDEDLVKWVIEKARRRIDAAIQKTADNLRDPKNRRTASDIASLFRQPSKAAIELARAAEVYEAAIDEVTQILQRQRNQSFGKDTEGPYRGDVDFDEQKRQAMGVQLTAEQLAIIAQLSGCAQSQRVEPCDRQLCFHMRYRSIDGSCNNLKYPKWGAALSPFYRLLPPVYENGVNQPVGWNPERLYFGYPKPSARLASYRLLADATKLQVHTRKLETFNQRIKMSLRFGNSTHDTSSPFDFPMNEKEALFDEDDRSSGMLMQWGQFLDHDLDFTPVDASTSRFSDGLGCNETCINDPPCFPILTPPGDPRIRQRCIGFARSSATCGSGSTSILLGRPQHREQLNQISAYLDASNVYGSEDFENSQLRDTLYDEGHLRGGMPTPAGKQLLPFNIRGQVDCQADPQQDFVPCFKAGDHRSNENLGLLSMHTIWMREHNRIADELRSLNPHWSGDRLYHEARKIVGALMQSITYRVWLPKVLGPRGMEMMGGETYPGYDSSVNPSISNEFATAAFRFGHTMVPPISFRLNENWEAIPEGHLLLHKAFFAPDKMLTDGGMDPILRGLLFHGVRDVIRRPSLNPELTERLFAMAHQLALDLASLNIQRGRDHGLQHYTSYAYTICGFGSSAAPDSFDDLADRIRDPAIREELRAVYGHPGNIDLFVGGVLEDVLPGARMGPTFACIIADQFKRLRAGDRLWYESPGLFTTAQLAELRDAGSYLSRVICENGDNITEVPLDAFLRPKSRKDLVPCSQVPKLNLALWKECPSPSG-TPFGSYSDIGVYFDQPLNRRRRSVPSED-SCEAKPPDALSFMAEVEQELEA 1341          

Query:  184 IVIIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEI-------GNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKSQCQSPMNVKNQ---------------------------FLEEVKFNELCS-----------------------NSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASIS--AEKGSRVEFSCRAHGYPVPEITWLWVKSNQV-RLETEGKYIVRKN---------------------------------NLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEE---SSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGIL-RENKVKLNLTT--AYEETLDFT--------TLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLL----------------------------RAHKITPDPNL---------------SAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLG--QYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWR-EFCGMKKA---ETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVT--LARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKEC 3519
            +  I+LG L     ST    C   C C  +++ CRR    +IP+I           L Y ++    +S++    F    D++ +DLS N+I ++EE A      L  L L+ N +  LP+ IF       +L   + N+L T+P SL++++ +K L L GN L+CGC +  FA  L        +  C +P  V  +                           F EE+   +L                         +S   S  AP+ IE P    VA G+++ F CQ   +   K+ W    N++    L+ + + L ++EVH +HEG Y C A N  G +S S  L++    KP I + P++ +   E G  +E +C A G P P + WL+  ++   RL T+G+Y+VR +                                  L I N+TE + EGRY CYA++ +GS +V++ + L   K   +++++     K PSR K        +I+ A+ +I+ A +KTA+ LRDP  +R+ SDI SLFRQPS AA+ELA+A++VYE  +D++T IL R+  +     T   Y    DF           LT EQLAII+QLSGC +S       +QLCFH +YRSIDG CNNL  P+ G+ALSP YRL+ P YENG+N P+GW   KL+ GY KPSARLVS RLL                            R+H  +   +                S M+MQWGQFLDHDLDFTPVDAS SRFSDGLGCN TC+ND PCFPILTPPGDPR+++ CIGF+RS ATCGSG +SI+LG+  +REQ+NQI+++LD SNVY S+  E ++LRD  YDEG LR G  TP+ K+LLPFNIRGQVDCQ DP +  VPCFKAGDHR+NENLGLL MHTIWMREHNR++DELR LN HW+GD++Y+E+RKIVGA+MQ ITY  WLP VLG  G++ +G   YPGY+  V+ TIS+ FATAA RFGHT++ PI +RL+EN+ETIPEG+L LHKAFFAPD+++ DGG+DPILRGL   G + +     +N EL E+LFAMAH++ALDL +LNIQRGRDHGL  Y S+  + CG+  +   ++F+D +  I    IRE++R +YGHPGN+DLF G VLE  + G  +GPT +C++ DQFKRLR GDR WYES   F  AQL++I+     L+R++C+N DNI+ V  + F   K+  + + CS +P+LNL  WKEC
Sbjct:    8 VAFIWLGLLTLFCTSTCQDACPGNCVCFSQSIVCRRSTETIIPKIPAFLDGPQGGALQYFAITNTKLSRVPTEAFVGLLDIMSIDLSNNEIEVIEEGAFQDLPILAHLLLRQNRLTQLPDNIFDTLPSLEELDL-SFNQLTTIPSSLQRMVGLKSLSLRGNPLHCGCGIVDFAQLLPYWESSLDRVTCATPAQVAGKSIKELGRQYFQAFEGTRHLGHWPDEYAFPEEISRKQLIRTRTPWPLPHCPVKDLGGEVVDNVDSSTGSYEAPQIIEAPVPVMVAEGERVFFVCQATGVPRPKISWILPTNNSQHVHLWDKRKILELREVHAYHEGTYTCVAKNQVGQVSHSVMLQLVDIVKPQITDAPSTKATVGEPGGDIELTCTARGRPRPTVDWLYTHTSSAKRLSTQGRYVVRSSAKLSTRTIQDLTYRDFLAQTDESLRLEGEEESVTLTIRNVTELDTEGRYTCYAANRAGSTRVTSQVAL---KTWTDMDDDYGGEDKDPSRVK-------RVIEKARRRIDAAIQKTADNLRDPKNRRTASDIASLFRQPSKAAVELARAAEVYEAAIDEVTQILQRQRNLSFGKDTEGPYRSDADFDEQKRQAMGVQLTAEQLAIIAQLSGCAQSQRVEPRDRQLCFHMQYRSIDGSCNNLKYPKWGAALSPLYRLLPPVYENGVNQPVGWNPEKLFSGYPKPSARLVSYRLLADATKLQVHTRKLETFNQRIKMSLKFNNRSHDTSSPFDFPLYEKEELFDEGDSSSGMLMQWGQFLDHDLDFTPVDASTSRFSDGLGCNGTCINDPPCFPILTPPGDPRIRQRCIGFARSSATCGSGSTSILLGRPQHREQLNQISAYLDASNVYGSEDFENSQLRDTLYDEGHLRGGMPTPAGKQLLPFNIRGQVDCQADPQQDFVPCFKAGDHRSNENLGLLSMHTIWMREHNRIADELRSLNPHWSGDRLYHEARKIVGALMQSITYRVWLPKVLGPRGMEMMGGETYPGYDSSVNPTISNEFATAAFRFGHTMVPPIYFRLNENWETIPEGHLLLHKAFFAPDKMLTDGGMDPILRGLLFHGIRDIIRRPSLNPELTERLFAMAHQLALDLASLNIQRGRDHGLQHYTSYAYKICGLGSSAAPDSFEDLADRIRDPAIREELRAIYGHPGNIDLFVGGVLEDVLPGARMGPTFACIIADQFKRLRAGDRLWYESPGLFTTAQLAEIRDAGSYLSRVICENGDNITEVPLDAFIRPKNHKDLVSCSQVPKLNLALWKEC 1266          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEI-------GNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGC-------ELRYFAGNL-RRIGLDFQKSQCQSPMNVKNQF------------------------------------LEEVKFNELCSNSFEAS------ELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPA--SISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQV-RLETEGKYIVRKN---------------------------------NLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGIL---RENKVKLNLTTAYEETLDFT--------TLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLL-RAHKI--------------------------TPDP-------------------NLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLG--QYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWR-EFCGMKKA---ETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQV--TLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPS 3531
            C   C C  ++V CRR     +P +           L Y +L  + +S++ A  F    DL+++DLS N++  VEE A      L  L L+ N + +LP+ +F       +L   + N+L T+P SLE+LI +K L L GN ++C C       +L+++ G++ R +     +   +S  ++  Q+                                    L + +  +L   + + +      ++AP+F+E P+ A VA G+++ F CQ   +   K+ W    N++ F  L+ + + L I+EVH +H G Y C A N  G I  S  L+I    KP I + P+  +++   GS VE  C A G P P I WL+  +    RL T+G+Y V                                     L I N++E + EGRY CYA++ +GS +V++V++L ++++E     ESS+  S   L    +  +I+ A+ +I+ A +KTA+ LRDP+ +R+ SDI SLFRQPS AA+ELA+A++VYE  +D++T IL   R   +  +   AY+   DF           LT EQLAII+QLSGC +      C +QLCFH +YRSIDG CNNL  P+ GSALSPFYRL+ P YENG+N P+GW   +LY GY KPSARLVS RLL  A K+                          T +P                     S M+MQWGQFLDHDLDFTPVDAS SRFSDGLGCNETC+ND PCFPI+TPPGDPR+++ CIGF+RS ATCGSG +SI+LGK  +REQ+NQIT+F+D SNVY S+  E ++LR+  YDEG+LR G  TPS K+LLPFNIRGQVDCQ DP +  VPCFKAGDHR+NENLGLL MHTIWMREHNR++DELR LN HW+GD+IY+E+RKIVGA+MQ ITY  WLP VLG  G++ +G   Y GY+  V+ TIS+ FATAA RFGHTL+ PI +RL+EN+E IPEG+L LHKAFFAPDR++ DGG+DPILRGL   G + +     +N EL E+LFAMAH++ALDL +LN+QRGRDHGL  Y ++  + CG+  +   ++FDD +  I    IRE++R VYGHPGN+DLF G VLE  + G  +GPT +C++ DQFKRLR GDR WYES   F  AQL++I++    L+R++C+N DNI+ V  + F   KS+ + + CS +P+LNL  WKEC  PS
Sbjct:   26 CPQGCVCFSQSVVCRRVQGNTLPTLPSYLPDPNGGALQYFALTLSKLSRLPAGAFVGLLDLMNIDLSNNELESVEEGAFQELPALVQLSLRQNRLTHLPDNLFDTVPSLEELDL-SYNQLTTVPASLERLIGLKTLILRGNPIHCSCGIVDFALKLQFWEGSVGRTVCASPNEVAGKSVSDLGRQYVQAFEGTRHLGYWPDEYVYPEEANRRPLVRTRTAWPLPQCREGDLGGETSDTTRRPLGPDVAPRFVETPEPAMVAEGERVFFTCQAAGVPTPKILWTLPTNNSQFIHLWNKRKILEIREVHGYHAGTYTCIAKNRLGEIGHSVSLQILDIVKPQITDAPSAQTMAGYAGSDVELVCTARGRPRPTIDWLYTHATSAKRLSTQGRYTVHSAKKLSTHTIQDLVSRDPLAQNDEVTRAEGEEESVTLTIRNVSEHDTEGRYTCYAANRAGSTRVTSVVSLKKARDE----AESSEGESDEDL----VKRVIEKARRRIDAAIQKTADNLRDPSNRRTASDIASLFRQPSKAAIELARAAEVYEAAIDEVTQILQRQRNKSLGKDEEGAYKGDEDFDEHKRLAMGVQLTTEQLAIIAQLSGCAQPQRVEPCDRQLCFHMRYRSIDGSCNNLKFPKWGSALSPFYRLLPPVYENGVNQPVGWNPERLYFGYPKPSARLVSYRLLGDATKLQVHTRKLQTFNERIKMSLKFNNRTYGTSNPFDVPRIGEEEKEDFFDEDDTSSGMLMQWGQFLDHDLDFTPVDASTSRFSDGLGCNETCINDPPCFPIITPPGDPRIRQRCIGFARSSATCGSGSTSILLGKPQHREQLNQITAFIDASNVYGSEEFENSQLRNTLYDEGQLRGGMPTPSGKKLLPFNIRGQVDCQADPQQDFVPCFKAGDHRSNENLGLLSMHTIWMREHNRIADELRSLNPHWSGDRIYHEARKIVGALMQSITYRVWLPKVLGPRGMEMMGGDTYTGYDSSVNPTISNEFATAAFRFGHTLVPPISFRLNENWEAIPEGHLLLHKAFFAPDRMLTDGGMDPILRGLLFHGVRDIVRRPSLNPELTERLFAMAHQLALDLASLNVQRGRDHGLQHYTAYAYKVCGLGSSAAPDSFDDLADRIRDPAIREELRAVYGHPGNIDLFVGGVLEDVMPGARMGPTFACIIADQFKRLRSGDRLWYESPGLFTVAQLAEIREAGSLLSRVVCENGDNITEVPLDAFLRPKSRKDLVPCSQVPKLNLALWKECPSPS 1270          

Query:  817 PKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEET-LDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP---CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            P+F   PQD  V  G  + F C+     +  + W    +    +   +      L I  V    +G Y C A +  G++ A+ +L I     P     P  +  E G+ V+  C A G P P ITW     + V++   GK+ +     ++ N   +   GRY C A +  G +  S V+T+              ++P  ++  +  +   +++A   I+ A   T   L D    R+  ++ +LFR P     +E A+A +++E+ L     +L +  V   L      T   +  L++P  L +I+ LSGC       +CS  +CFH+KYRS DG CNNL +P  G++L+ F RL+K  Y+NG N P G T  + + G++ P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C   C ND PCFPI+ PP DPR +R    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA E+RDL    G+L+ G V  + K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP +LG  G+K +G Y GY+  V++ I + FATAA RFGHTLINPILYRLDENF+ I +G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   + Q++N EL E+LF+MAH VALDL A+N+QRGRDHG+  YN +R FC +  A+TFDD   EI +  +REK++++YG P N+DLF   ++E  V G  +GPTL CLL  QFKR+RDGDRFWYE+   F PAQL+Q+KQ +L R+LCDN DNI+R+Q +VF +A+    F  C ++P+++L  W++C +  R
Sbjct:  405 PQFTVSPQDQSVLEGHTVDFPCEATGYPQPVIAWTRGGSPLPGDRRHVVLSTGTLRISRVAPHDQGQYECQAVSPVGTVRAAVQLNIQQRVTPVFTSAPRDLEVESGTDVQIPCSAQGEPTPVITW---NKDGVQVTESGKFHINPEGYLVVNDVGTADGGRYECVARNSIGYSSASMVLTV--------------QVPQVSREGDSYVSTSLEEAIRSIDRAIDSTRRHLFD-GSPRTPGELLALFRYPRDPYTVEQARAGEIFEQTL-----LLIQRHVNHGLMVDTNGTAFRYNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRSHDGTCNNLQHPMWGASLTAFERLLKSVYDNGFNLPRGAT-DRRHSGFALPLPRLVSTTMIGTETITPDERYTHMLMQWGQFLDHDLDSTVVSLSQSRFSDGQLCTSVCTNDPPCFPIMFPPNDPRQRRGGARCMFFVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSRHEADEIRDLAGHRGQLKQGIVQRTGKPLLPFASGPPTECMRDENESPIPCFLAGDHRANEQLGLTAMHTVWFREHNRIAAELLRLNPHWDGDTIYHEARKIVGAQMQHITYSHWLPKILGEAGMKIMGDYHGYDPNVNAGIFNAFATAAFRFGHTLINPILYRLDENFQPIQQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVTTQLLNTELTERLFSMAHAVALDLAAMNVQRGRDHGIPPYNDYRVFCNLTSAQTFDDLRNEIRNPTVREKLQRLYGTPMNIDLFPALMVEDIVPGSRLGPTLMCLLATQFKRVRDGDRFWYENAGVFSPAQLTQLKQASLTRVLCDNGDNITRIQSDVFSVAEFPHGFGSCDDVPKIDLRMWQDCCEDCR 1292          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSI-SASAKLK-IAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C  +C C   TV C     + +P + + + T L L  N I  +    F+  K+L  + L+ N I  +   A      L+ LYL  N IE L  + F+      +L    NNR+  L + +   L  +KRL L  N L C CEL + A  L++    G     + C+ P  ++ + +  +   EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      DT  N L   +  L I++  E  +G+Y C A N  G + +    L+      +P  V  P +     G  V   C A G P P ++  W + ++  L  + +  I     L I+N+ +++  G+Y C+AS+   +   +A I +
Sbjct:   32 CPSRCLCFRTTVRCMHLNLETVPAV-SPQTTILDLRFNKIKDLQLGSFRRLKNLNTLLLNNNHIRRIPRAAFEDLENLKYLYLHFNNIEALEPESFTHLPKLERLFLH-NNRITHLTLGTFSHLQAMKRLRLDSNTLNCDCELLWLADLLKQYAESGNAQAAATCEFPSRLQGRSVATLTAEELNCE--------VPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTGEVTLRYFGTPSRPSFVIQPQNTEVLVGQSVTLECSAAGQPQPRVS--WTRGDRSPLPNDARINITPSGGLYIQNVNQAD-GGQYTCFASNNVDTIHATAYIIV 401          

Query:  817 PKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEET-LDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP---CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            P+F   PQD  V  G  + F C+     +  + W    +    +   +      L I  V    +G Y C A +  G++ A+ +L I     P     P  +  E G+ V+  C A G P P ITW     + V++   GK+ +     ++ N   +   GRY C A +  G +  S V+T+              ++P  ++  +  +   +++A   I+ A   T   L D    R+  ++ +LFR P     +E A+A +++E+ L     +L +  V   L      T   +  L++P  L +I+ LSGC       +CS  +CFH+KYRS DG CNNL +P  G++L+ F RL+K  Y+NG N P G T  + + G++ P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C   C ND PCFPI+ PP DPR +R    C+ F RS   CGSG +S+++  ++ REQ+NQ+TS++D SNVY S   EA E+RDL    G+L+ G V  + K LLPF      +C  D  ++ +PCF AGDHR NE LGL  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP +LG  G+K +G Y GY+  V++ I + FATAA RFGHTLINPILYRLDENF+ I +G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   + Q++N EL E+LF+MAH VALDL A+N+QRGRDHG+  YN +R FC +  A+TFDD   EI +  +REK++++YG P N+DLF   ++E  V G  +GPTL CLL  QFKR+RDGDRFWYE+   F PAQL+Q+KQ +L R+LCDN DNI+R+Q +VF +A+    F  C ++P+++L  W++C +  R
Sbjct:  429 PQFTVSPQDQSVLEGHTVDFPCEATGYPQPVIAWTRGGSPLPGDRRHVVLSTGTLRISRVAPHDQGQYECQAVSPVGTVRAAVQLNIQQRVTPVFTSAPRDLEVESGTDVQIPCSAQGEPTPVITW---NKDGVQVTESGKFHINPEGYLVVNDVGTADGGRYECVARNSIGYSSASMVLTV--------------QVPQVSREGDSYVSTSLEEAIRSIDRAIDSTRRHLFD-GSPRTPGELLALFRYPRDPYTVEQARAGEIFEQTL-----LLIQRHVNHGLMVDTNGTAFRYNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRSHDGTCNNLQHPMWGASLTAFERLLKSVYDNGFNLPRGAT-DRRHSGFALPLPRLVSTTMIGTETITPDERYTHMLMQWGQFLDHDLDSTVVSLSQSRFSDGQLCTSVCTNDPPCFPIMFPPNDPRQRRGGARCMFFVRSSPVCGSGMTSLLMNSVYPREQMNQLTSYIDASNVYGSSRHEADEIRDLAGHRGQLKQGIVQRTGKPLLPFASGPPTECMRDENESPIPCFLAGDHRANEQLGLTAMHTVWFREHNRIAAELLRLNPHWDGDTIYHEARKIVGAQMQHITYSHWLPKILGEAGMKIMGDYHGYDPNVNAGIFNAFATAAFRFGHTLINPILYRLDENFQPIQQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVTTQLLNTELTERLFSMAHAVALDLAAMNVQRGRDHGIPPYNDYRVFCNLTSAQTFDDLRNEIRNPTVREKLQRLYGTPMNIDLFPALMVEDIVPGSRLGPTLMCLLATQFKRVRDGDRFWYENAGVFSPAQLTQLKQASLTRVLCDNGDNITRIQSDVFSVAEFPHGFGSCDDVPKIDLRMWQDCCEDCR 1316          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSIS------------------------KIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNEL-CSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSI-SASAKLK-IAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C  +C C   TV C     + +P + + + T L L  N I                         +I    F++ ++L ++ L  N+I  ++  A  G + LE LYL  N IE L  + F+      +L    NNR+  L + +   L  +KRL L  N L C CEL + A  L++    G     + C+ P  ++ + +  +   EL C          P+    PQD  V  G+ + F C+ E   + ++ W    N      DT  N L   +  L I++  E  +G+Y C A N  G + +    L+      +P  V  P +     G  V   C A G P P ++  W + ++  L  + +  I     L I+N+ +++  G+Y C+AS+   +   +A I +
Sbjct:   32 CPSRCLCFRTTVRCMHLNLETVPAV-SPQTTILDLRFNKIKDLQLGSFRRLKNLNTLLLNNNHIRRIPRAAFEDLENLKYLYLYKNEIQSIDRQAFKGLVSLEQLYLHFNNIEALEPESFTHLPKLERLFLH-NNRITHLTLGTFSHLQAMKRLRLDSNTLNCDCELLWLADLLKQYAESGNAQAAATCEFPSRLQGRSVATLTAEELNCE--------VPRITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDTRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTGEVTLRYFGTPSRPSFVIQPQNTEVLVGQSVTLECSAAGQPQPRVS--WTRGDRSPLPNDARINITPSGGLYIQNVNQAD-GGQYTCFASNNVDTIHATAYIIV 425          

Query: 1531 SDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITP--DPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR-PCIGFSRSIATCGSGQSSIILGKL-HYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQI------DPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRL-GQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPE-GNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPW 3510
            SD   L +QPS       +A+D  E+ L  +    R          A++ +++ T L++P +L +I +L+GC    +   C      +K YR+ +  CNN  NP  G+A +P    +   YE+GI+ P+GW  G+L++G S P  RLVS+++L         D   + +V  +GQ+ DHDL FTP   S   FS G+ C+ +C    PCFPI  P GDPR+ R  CI   RS  TCGSG ++ + G   + R+Q+N +T+FLD   +Y SD   A ELRDL+ D+G+L V      N R LLPF       C              VPCF AGD R +EN+ L  +HT++MREHNRL+D LR LN HW+ + +Y E+RKI+GA  Q I    +LP ++G + IK+L G YPGYN  +D +I++VFATAA RF H  I P+++R+DENFE  P+  ++PL++AFF+P RV+ +GGIDP++RGL +  +K  + + ++   L E+LFA    +ALDL +LN+QR RDHGL  Y +WR+FC + +     + +  + ++++  ++ + Y  P N+D++   + E  V GG VGP  SCL+  QF+++R GDR W+E    F   Q + +  V+LARI+CDN+  + RV  N F  + SK  F+DC+ IP+++L PW
Sbjct:   69 SDKLRLLKQPSRKTRSAVRAADYLEQTLRIIADKTRH---------AHKRSINATELISPNELRMIERLTGCAAQVQPPSCRTTPNVNK-YRTANSVCNNRKNPLLGAANTPLASWLPTIYEDGISQPVGWNPGRLHNGVSLPLVRLVSNQILSMQDADAKGDSEYTHLVTFFGQWNDHDLSFTPFSPSIRSFSSGIDCDASCEQSEPCFPIRIPNGDPRISRNSCIPVFRSAPTCGSGNTAFMFGGTPNVRQQINSLTAFLDVGQLYGSDQGLARELRDLSNDKGRLLVNDRFQDNGRDLLPFTKVASNMCSTRNRILNTTGLPEVPCFIAGDVRVDENIALTSLHTLFMREHNRLADILRVLNPHWSSETLYQEARKIMGAYHQIIVIRDYLPHIVGPDAIKKLLGPYPGYNPNIDPSIANVFATAAYRFAHVTIQPLVFRVDENFENHPKFPSVPLYEAFFSPWRVVFEGGIDPLIRGLISRPAKLNQQNHMLVNALRERLFAFTSHIALDLASLNMQRSRDHGLQGYTAWRKFCNLSEPRNQAELATVLNNTDLARRLLEHYKTPANIDVWLAGIAEPFVPGGRVGPLFSCLIGTQFQKIRLGDRLWWEKPGVFTRTQRASLASVSLARIICDNT-GVKRVPANPFRFSSSK-NFVDCNEIPQIDLTPW 729          

Query: 1531 SDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITP--DPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR-PCIGFSRSIATCGSGQSSIILGKL-HYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQI------DPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRL-GQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPE-GNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPW 3510
            SD   L +QPS       +A+D  E+ L  +    R          A++ +++ T L++P +L +I +L+GC    +   C      +K YR+ +  CNN  NP  G+A +P    +   YE+GI+ P+GW  G+L++G S P  RLVS+++L         D   + +V  +GQ+ DHDL FTP   S   FS G+ C+ +C    PCFPI  P GDPR+ R  CI   RS  TCGSG ++ + G   + R+Q+N +T+FLD   +Y SD   A ELRDL+ D+G+L V      N R LLPF       C              VPCF AGD R +EN+ L  +HT++MREHNRL+D LR LN HW+ + +Y E+RKI+GA  Q I    +LP ++G + IK+L G YPGYN  +D +I++VFATAA RF H  I P+++R+DENFE  P+  ++PL++AFF+P RV+ +GGIDP++RGL +  +K  + + ++   L E+LFA    +ALDL +LN+QR RDHGL  Y +WR+FC + +     + +  + ++++  ++ + Y  P N+D++   + E  V GG VGP  SCL+  QF+++R GDR W+E+   F   Q   +  ++LARI+CDN+  + +V  + F +  +K EF++CS+I  ++  PW
Sbjct:   21 SDKLRLLKQPSRKTRSAVRAADYLEQTLRIIADKTRH---------AHKRSINATELISPNELRMIERLTGCAAQVQPPSCRTTPNVNK-YRTANSVCNNRKNPLLGAANTPLASWLPTIYEDGISQPVGWNPGRLHNGVSLPLVRLVSNQILSMQDADAKGDSEYTHLVTFFGQWNDHDLSFTPFSPSIRSFSSGIDCDASCEQSEPCFPIRIPNGDPRISRNSCIPVFRSAPTCGSGNTAFMFGGTPNVRQQINSLTAFLDVGQLYGSDQGLARELRDLSNDKGRLLVNDRFQDNGRDLLPFTKVASNMCSTRNRILNTTGLPEVPCFIAGDVRVDENIALTSLHTLFMREHNRLADILRVLNPHWSSETLYQEARKIMGAYHQIIVIRDYLPHIVGPDAIKKLLGPYPGYNPNIDPSIANVFATAAYRFAHVTIQPLVFRVDENFENHPKFPSVPLYEAFFSPWRVVFEGGIDPLIRGLISRPAKLNQQNHMLVNALRERLFAFTSHIALDLASLNMQRSRDHGLQGYTAWRKFCNLSEPRNQAELATVLNNTDLARRLLEHYKTPANIDVWLAGIAEPFVPGGRVGPLFSCLIGTQFQKIRLGDRLWWENRGVFTKRQRDSLITMSLARIICDNT-GLKKVPADPFRLKANKAEFVECSSIAEIDFTPW 682          

Query: 1531 SDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITP--DPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR-PCIGFSRSIATCGSGQSSIILGKL-HYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQI------DPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRL-GQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPE-GNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPW 3510
            SD   L +QPS       +A+D  E+ L  +    R          A++ +++ T L++P +L +I +L+GC    +   C      +K YR+ +  CNN  NP  G+A +P    +   YE+GI+ P+GW  G+L++G S P  RLVS+++L         D   + +V  +GQ+ DHDL FTP   S   FS G+ C+ +C    PCFPI  P GDPR+ R  CI   RS  TCGSG ++ + G   + R+Q+N +T+FLD   +Y SD   A ELRDL+ D+G+L V      N R LLPF       C              VPCF AGD R +EN+ L  +HT++MREHNRL+D LR LN HW+ + +Y E+RKI+GA  Q I    +LP ++G + IK+L G YPGYN  +D +I++VFATAA RF H  I P+++R+DENFE  P+  ++PL++AFF+P RV+ +GGIDP++RGL +  +K  + + ++   L E+LFA    +ALDL +LN+QR RDHGL  Y +WR+FC + +     + +  + ++++  ++ + Y  P N+D++   + E  V GG VGP  SCL+  QF+++R GDR W+E+   F   Q   +  ++LARI+CDN+  + +V  + F +  +K EF++CS+I  ++  PW
Sbjct:   69 SDKLRLLKQPSRKTRSAVRAADYLEQTLRIIADKTRH---------AHKRSINATELISPNELRMIERLTGCAAQVQPPSCRTTPNVNK-YRTANSVCNNRKNPLLGAANTPLASWLPTIYEDGISQPVGWNPGRLHNGVSLPLVRLVSNQILSMQDADAKGDSEYTHLVTFFGQWNDHDLSFTPFSPSIRSFSSGIDCDASCEQSEPCFPIRIPNGDPRISRNSCIPVFRSAPTCGSGNTAFMFGGTPNVRQQINSLTAFLDVGQLYGSDQGLARELRDLSNDKGRLLVNDRFQDNGRDLLPFTKVASNMCSTRNRILNTTGLPEVPCFIAGDVRVDENIALTSLHTLFMREHNRLADILRVLNPHWSSETLYQEARKIMGAYHQIIVIRDYLPHIVGPDAIKKLLGPYPGYNPNIDPSIANVFATAAYRFAHVTIQPLVFRVDENFENHPKFPSVPLYEAFFSPWRVVFEGGIDPLIRGLISRPAKLNQQNHMLVNALRERLFAFTSHIALDLASLNMQRSRDHGLQGYTAWRKFCNLSEPRNQAELATVLNNTDLARRLLEHYKTPANIDVWLAGIAEPFVPGGRVGPLFSCLIGTQFQKIRLGDRLWWENRGVFTKRQRDSLITMSLARIICDNT-GLKKVPADPFRLKANKAEFVECSSIAEIDFTPW 730          

Query:  814 APKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNS--LYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKL--RDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLD-FTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP-CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            AP+FI  P+D  V  G  +   C+ +      + W    +    +       +  L I  V    +G + C A N  G   A+ +L + P   P     P+ I+ + G  V  +C A G P P + W     + V +   GK+ V     +         +GRY C A +  G A  S ++++            ++ +  R++  +  +   ++ A   ++ A   T   L  R P+   S SD+ +LFR P     +E A+A +++E+ L      L +  V   LT     T + +  L++P  L +I+ LSGC       +CS  +CFH+KYR+ DG CNNL +P  G++L+PF RL+KP YENG+N P G+T     +G+  P  RLVS+ ++    +TPD   + ++MQWGQFLDHDLD T    S SRFSDG  C   C ND PCFPI  PP D R +   C+ F+RS   CGSG +S+++  +H REQ+NQ+TS++D SNVY S   E+ +LRDL    G LR G V  S K LLPF      +C  D  ++ VPCF AGD R+NE LGL  MHT+W REHNR++ EL  LN HW+GD +Y+E+RK+VGA++QH+TY  WLP +LG  G KRLG Y GY+  V+  I + FATAA RFGHTLINP+LYRLD++F+ IP+GNLPLH+AFF+P R++ +GGIDP+LRG+FA+  K     +++N EL E+LF MAH VALDL A NIQRGRDHG+  YN +R FC +  A  F+D   EI +  IREK+R++YG P N+DLF   ++E+ V G  +GPTL CLL+ QF+RLRDGDRFWYE+   F PAQL+Q++Q +LAR+LCDN D+I RVQR+VF +A+    ++ C +IPR++L  W++C +  R
Sbjct:  369 APQFILAPEDQVVTEGHTVDLHCEAQGRPLPVIAWTKAGSQLPSDRRLTVLSSGTLRIARVALHDQGQFECQAVNVVGVRRAATQLTVLPRVTPVFSVTPSDITTDSGRDVRIACSAQGEPQPSLMW---AKDGVHITESGKFHVSAEGYLEIRDAGPADQGRYECIARNSIGHASTSMLLSVTAFTRR-----AAAPVAERSRSGDSFVERSVQQAIHSVDSAINSTRRALFGRQPH---SPSDLLALFRYPRDPYTVEQARAGEIFERTLQ-----LIQEHVGNGLTVDANGTSEWYNDLVSPRYLNLIANLSGCTAHRRSDNCSD-ICFHQKYRTHDGTCNNLQHPMWGASLTPFERLLKPVYENGLNRPRGFTPEAPVNGFPLPQPRLVSTAMIGTESVTPDDRYTHILMQWGQFLDHDLDLTVAALSQSRFSDGRPCGAVCTNDPPCFPIAIPPDDRRARDARCMFFARSSPVCGSGMTSLLMNSVHPREQINQLTSYIDASNVYGSSERESRDLRDLAGRRGSLRRGLVQRSGKALLPFATGPPTECMRDENESPVPCFLAGDQRSNEQLGLTAMHTLWFREHNRVAAELLRLNPHWDGDAVYHEARKVVGALVQHVTYAHWLPKILGEVGTKRLGDYRGYDPNVNVGIFNAFATAAFRFGHTLINPVLYRLDDSFQPIPQGNLPLHRAFFSPYRIVNEGGIDPLLRGMFAVPGKMRVPSELLNTELTERLFFMAHTVALDLAATNIQRGRDHGIPPYNDYRVFCNLTSARDFEDLRNEIRNPHIREKLRRLYGTPQNIDLFPALMVEELVPGTRLGPTLLCLLLTQFQRLRDGDRFWYENPGVFTPAQLTQLRQASLARVLCDNGDSIERVQRDVFAVAEFPHGYVGCQDIPRVDLRLWQDCCEDCR 1265          

Query:  334 TYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXX-----------------------ANNRLKTLPI-SLEKLINVKRLELYGNMLYCGCELRYFAGNLRRI---GLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQW----LFIKEVHEFHEGIYICTASNNKGSISASA---KLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEE 1392
            +Y  L  N I +I    FK+ K+L  + L+ N I  +   A      L+ LYL  N I+ +    F       +L                           NNRL  +   +  +L +++RL L  N L C CEL + A  LR     G     + C+ P  ++ + +  +   E    S       P+    P D  V  G+ +   C+ E   +  + W    N+        RN      L I++     +G Y C A N  G + A     +    P    ++++ P       G  V   C A G+P P ++W    S Q  L  + ++ +     L +E     + EGRY C+AS+   S + SA I L++S  +  L  E
Sbjct:    2 SYRDLRFNRIREIPPGAFKKLKNLNTLLLNNNHIKRIPRRAFEDLESLKYLYLYKNEIQSIDRHAFKGLVSLEQLYIHFNHIEVLEPNTFVDLPKLERLFLHNNRLSRIATGTFTQLSSLRRLRLDSNRLVCDCELVWLAELLRAFAGSGGTLAAATCEHPRRLQGRSVSSITAQEFHCES-------PRITSEPHDVDVTPGNTVYLRCRAEGNPKPAIIWLHNSNEIAMAEDERRNLLQDGTLMIRDTRHTDQGTYQCMARNVAGEVKAPEVVLRYFDVPAPPTFVIQ-PHDTEVLVGESVTLECSAGGHPAPRVSWTRDDSEQ--LPADPRFSVTASGGLHVERAGPGD-EGRYTCHASNNQDSIRASATI-LLKSAPQFILAPE 377          

Query: 1087 PYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILREN-KVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQ---RPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARI-LCDNSDNIS----RVQRNVFFMAKSKLEFIDCSNIPRLN-LIPWKECYDPSRLTPEDQVPGLSPS-RSRRSTNEF---QDQNCKSKTNQCSS 3642
            P     P  +++  G  V+  C A G P P ITW     + V+L   GK+ +  +  L I ++  ++ +GRY C A +  G A  + ++++               +P  N+  +  +   I++A   ++ A   T  +L D N  R+ +D+ +LFR P     +E A+A +++E+ L  +   +R   KV +N  TAY     +  L++P  L +I+ LSGC       +CS  +CFH++YR+ DG CNNL +P  G++L+ F RL+KP YENG + P G     L++G+  P  R++S+ L+    +TPD   S ++MQWGQFLDHD+D T    S +RFSDG  C+E C +D PCFPI  PP DPRV+     C+ F RS   CGSG +S+++  +  REQ+NQ+TS++D SNVY S   E+ E+RDL    G L+ G +  S K LLPF      +C  D  ++ +PCF AGD R NE + L  +HT+W+REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY  WLP +LG  G+KR+G Y GY+  V+  I + FATAA RFGHTLINP+L+RL+ENF+ IPEG+L L +AFF+P RV+ +GGIDP+LRGLF +  K     +++N EL EKLF MAH VALDL A+NIQRGRDH +  YN +R FC +  A  F+    EI + ++REK+R++YG P N+DL+   + E  +    VGP+L CL + QF RLRDGDRFWYES   F PAQL+QIKQ +LAR+ LC    NI      + R + F+  + L      ++P +N    WK      R     Q   +S   R+RRST EF   +DQ  + K  + SS
Sbjct:    3 PVFTTSPTDVASVAGRDVQILCSAQGEPTPIITW---SKDGVQLTESGKFHLTSEGFLTIRDVGPAD-QGRYECIARNSIGHASTNMLLSV--------------HVPEGNRTGDSFVESSIQEAIFSVDSAINSTRRELFDRN-PRTPNDLLALFRYPRDPFTVERARAGEIFERTLQIIQEHVRGGLKVDMN-GTAYN--YHYNNLVSPYYLDLIANLSGCTAHRHVPNCSD-ICFHRRYRTQDGTCNNLQHPMWGASLTAFERLLKPVYENGFSAPRGLGGAALHNGHQLPLPRVISTTLVGTETVTPDDRYSHLLMQWGQFLDHDMDLTVAALSQARFSDGRPCSEACTDDPPCFPIAVPPDDPRVRGGGARCMFFIRSSPVCGSGMTSLLMNSVFPREQINQLTSYIDASNVYGSTERESAEVRDLASQRGLLKQGVIQRSGKSLLPFATGPPTECMRDERESPIPCFLAGDQRANEQVALTALHTLWLREHNRIATELLRLNPHWDGDTIYHEARKIVGAQMQHITYAHWLPKILGDVGMKRMGDYRGYDPNVNGGIFNSFATAAFRFGHTLINPVLHRLNENFQPIPEGHLSLRQAFFSPYRVVNEGGIDPLLRGLFGVAGKMRVPAELLNLELTEKLFHMAHTVALDLAAMNIQRGRDHAIPPYNDFRVFCNLTAAADFEHLRNEIKNPDVREKLRRLYGTPLNIDLWPALIAEDIIPSTRVGPSLMCLFLTQFSRLRDGDRFWYESPGVFTPAQLTQIKQASLARVLLCGKMKNIGINTKSLSRLINFIHGNFLH----PHMPPVNPAATWKSWVSDCRT--RGQFRAISGHFRTRRST-EFSFPEDQPSRRKQKRASS 840          

Query: 1690 FTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHG---YSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP----------------CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVG-PVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGL----LVMHTIWMREHNRLSD----------ELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIK-RLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQ----VYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDR-FWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKEC 3519
            +  L++P  L +I+ LSGC        CS   CFH++YR++DG CNNL +P  G++L+ F RL++P YENG N P G  A         +  P+ R VS+ L+   KITPD   + M+MQWGQFLDHD+D T V  S +RFSDG  C   C +D PCFPI   P DPR  R                 C+ F RS   CGSG +S+++  +  REQ+NQ+TS++DGSNVY S   EA ++RD +   G LR G  V  + K LLPF      +   D  ++ +PCFK GD R+NE LGL    +  H +  R+H  +S            LR LN HW+ D IY+ESRKIVGA MQHITY  WLP VLG++ ++  L  Y GY+  V+S I + FATAA RFGHTLINP+L RL+E+F+ IPEG+LPLH+AFF+P R++ +GGIDP+LRGLFA  +K     +++N EL EKLF MAH VALDL ++N+QRGR+HGL SY ++REFC +  A  F+  SGEI    +REK+R+    ++  P N     GA+    +     G     L  +QF+RLRDGDR FWYE+   F PAQL+QI Q +L+R+LCDN D I+ V  + F ++     ++ C  +P ++L  W++C
Sbjct:    3 YNDLVSPRYLELIANLSGCTAHRRAPSCSDA-CFHQRYRTVDGSCNNLQHPMWGASLTAFARLVEPAYENGFNEPRGGGASGRGRPRRGFPLPTPRRVSAELVGTEKITPDERHTHMLMQWGQFLDHDMDLTVVSPSQARFSDGEPCARACTDDPPCFPIELLPDDPRGGRRGGGGGGAAAAAAAAGRCMFFVRSSPVCGSGATSLLMSSVLPREQINQLTSYIDGSNVYGSSEREAADVRDRSSRRGLLRRGIAVGAAGKHLLPFATGPPTEHMRDERESPIPCFKKGDQRSNEQLGLTSPRVSSHPLVRRDHALVSSPPPPPASTLVRLRQLNPHWDSDTIYHESRKIVGAQMQHITYAHWLPKVLGADAMRSELRPYAGYDPSVNSAIFNSFATAAFRFGHTLINPVLLRLNESFQPIPEGHLPLHRAFFSPFRLVNEGGIDPLLRGLFATPAKKRVPSELLNLELTEKLFHMAHSVALDLASMNVQRGREHGLPSYAAYREFCNLTAAGDFEGLSGEIRDPVVREKLRKCTHGLFFLPENEKCAGGAIARWPIGSTSWGAGRQXLFTEQFRRLRDGDRLFWYENPGVFSPAQLTQIHQSSLSRVLCDNGDAITLVPPDAFAVSTYPQGYVACGTLPHVDLRMWQDC 651          

Query: 1813 DGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDP-NLSAMVMQWGQ-FLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRV---GPVTPSNKRLLPFNIRGQVDCQIDPAKA----HVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKA------FFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSS--EIREKMRQVY-GHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHD--QFEPAQLSQIKQVTLARIL-CDNSDNISRVQRNVFF 3444
            DG  NNL N   GS  S   RL    + +G+         +++   + P+AR +SS ++R     P   N + + + +GQ  +D  +D   V       +  +  N+T  ++SP + +L        QR     S+   + GS  ++        R  VN++TS+LDGS +Y         LR  T+D G L+    G +   + R L       +D      KA    H   ++ G+ R NE+  L  + T+W+R HN L++++R  N   +  +++  +RK V A+ Q+I    WLP +LG    K + +Y GY   V+ +IS  F  AAMRFGHT++ P +Y+ D++    P      + A      ++  +       +D  + G+      A + D V+  +L++ ++       LDL A+NIQRGRDHGL SY + R+   +     ++D +  +     E+  +   VY G    ++L+ G +LE +   G  GP  S +L+DQF+R+RDGDRFW+E+ +   F  + +  +++   + +L      N   +Q  VFF
Sbjct:   36 DGWYNNLDNIHWGSTGSKLLRLAPASFADGVY--------QMWDNPTVPNARRLSSSVMRGESGLPSALNRTVLAVFFGQHIVDEIVDTRQVGCPAEFLNIPIPWNDTAFSNSP-YHVLP------FQR-----SQWYKSTGSAPNNP-------RMPVNKVTSWLDGSAIYGCSRSWCHALR--TFDRGMLKSSENGSLPAVSDRSLRL-----IDAPSPSYKAGSSGHSNLYEFGNSRGNESPFLKAIGTVWLRYHNHLAEKMRQENPEMSDKELFINARKWVVAVYQNIVLYEWLPAMLG----KNMAEYKGYKPHVNPSISVEFQAAAMRFGHTMVPPGVYKRDDSCNFKPSDPKSQYNASRMCNNYWTKEVFRSGHEVDEFVLGM--ASQIAEQEDHVIVEDLLDSMYGPMKASRLDLMAINIQRGRDHGLPSYVNMRKAMNLDPITKWEDINPTLSQKNPEMESRSALVYNGDISRLELWPGGLLECQ---GGPGPLFSRILVDQFERIRDGDRFWFENTNNGMFTKSDVEAVRRTKFSSVLQAVMRVNNRTIQDEVFF 557          

Query: 1813 DGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDP-NLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP---CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAG---------DHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDE--NFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHP-GNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQ--FEPAQLSQIKQVTLARILCDNSD-NISRVQRNVFF 3444
            DG  NNL+N   GSA S   RL    + +G+         +++   + P+AR +SS ++R     P   N + + + +GQ   H +D    +  ++R +   GC       +  F I  P  DP         + F RS     +G S+      + R  VN++TS+LDGS +Y         LR  T+D G +R      S++  LP  + G     ID   A  P ++ G         + R NEN  L  + T+W+R HN  + ++   ++ W+ + ++  +RK V  + Q+I    WLP +L     + + +Y GY   V   I+  F +AAM+F  T++ P +Y  +   +F  +    L  H     P +   D  +D I+ G+ +    A + D ++  +L++K++        DL AL IQ+GRDHG  +YN  R    M     ++DF+      +I++  R V+     ++D++ G +LE +   G  GP  S +L+DQF+R+RDGDRFW+E+ +   F   ++  +     + +L    D + S +Q  VFF
Sbjct:   13 DGWYNNLLNIDWGSAGSKLLRLAPASFADGVY--------QMWDEPAVPNARRLSSSVMRGESGLPSALNRTVLAVFFGQ---HIMD----EIMDTRRA---GC------PAEFFNIPIPAEDPAFSNSPYKVLPFQRSQWDKTTGASTN-----NPRTPVNKVTSWLDGSAIYGPSRSWCQALR--TFDRGMMR-----SSDEESLP-PVSGHSLQLID---APSPSYETGSSTNKTVYGNPRGNENPFLKALGTVWLRYHNFWAAKIHSEHSDWSDEDVFLNARKWVIGVYQNIVLYEWLPAMLNGSTFQ-VSEYKGYKPHVHPGIAVEFESAAMKFHQTMMPPGVYSRNATCSFNQVNASRLCNHFWTNMPFKSGRD--VDEIIMGMSS--QIAEREDHIIVEDLLDKMYGPLKATRSDLMALTIQQGRDHGAPTYNDMRRALHMTPIAEWEDFNHTNAQVKIQKGERAVHDKALSSIDVYVGGLLECQ---GGPGPLFSRILVDQFERIRDGDRFWFENTNNGIFTEDEVRDVLATRFSHVLQTVMDIDNSSIQGEVFF 527          

Query: 1690 FTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP-CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRV-GPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVK-SDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPW 3510
            F  LL+P  + +I+ LSGC       +CS  LCFH  YRS DG CNNL +P  G +L+P  RL++P YENG N PIGW      +  ++PSARLVS+ L+ A  +T D   + M+MQWGQFLDHD+DFT    S SRFSDG  C  TC N SPCFPI  P GDPR++R  C+ F+RS + CG+G +S+   K+  REQ+NQIT+F+D SN+Y S   +A  LRDL   +G L+   P+ P+ K LLP +    V+C + P  + VPCF AGDHR NE +GLL MHT+WMREHNR++ EL  LN HW G+KIY+E+RKIVGA +QHITY+AW+P ++G +G+ RLG YPGYN   D TI + FATAA RFGH LI PI+ RL+ +F  IPEGN+PLHKAFF+P R++ +GGIDP+LRGLFA  SK+ + SD+++N EL E+LF MAH VALDLGALNIQRGRDH L  YNSWR+ C +  AE+FDD   EI S++IR ++ ++Y  P NVDL+   +LE    GG VG   SC+L++QFKRLRDGDRFWYE+   FEPAQL+QI+  +LAR+LCDN DNI  VQR+VF  A++   ++ C  IPR++L  W
Sbjct:   16 FFDLLSPAYIKMIANLSGCSAHRRMNNCSD-LCFHLNYRSADGTCNNLQHPMWGGSLTPLKRLLRPIYENGFNAPIGWI-----NKNARPSARLVSTELVAAANVTDDKKHTHMLMQWGQFLDHDMDFTVTSLSFSRFSDGADCTATCENQSPCFPIQIPDGDPRIRRARCMQFTRSSSVCGTGTTSVFFSKVTPREQMNQITAFIDASNIYGSSDEDARNLRDLR-SKGLLKTSAPIEPNGKPLLPPHRDTPVEC-LQPHDSPVPCFLAGDHRANEQIGLLSMHTLWMREHNRIASELSRLNPHWTGEKIYHEARKIVGAQLQHITYSAWIPKIVGPKGMARLGPYPGYNPNTDPTIINAFATAAFRFGHGLIKPIINRLNSSFLPIPEGNIPLHKAFFSPYRIVNEGGIDPVLRGLFAEASKSRENSDELVNTELTERLFEMAHAVALDLGALNIQRGRDHALPGYNSWRKLCNLSVAESFDDLKNEISSADIRARLEKLYKDPSNVDLWLAGLLEDLEPGGQVGKVFSCILVEQFKRLRDGDRFWYENPSTFEPAQLTQIRMSSLARVLCDNGDNIQLVQRDVFLRAETHGGYVSCEAIPRMDLRMW 617          

Query: 1801 YRSIDGKCNNLINPRRGSALSPFYRLMKPEY--ENGINTPIGWTAGKLYHGYSKPSARLVSSRL-LRAHKITP-DPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVN-DSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAH-EVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVY-GHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE 3516
            YR++DG CNNL NP  GSA  PF R+  P Y  +N ++ P+G+         S PS   +S    + + +  P +   S M+MQWGQFLDHD+ FT  ++  ++      C+ +  + +SPCFPI+ P GD      C  F+RS A C +   ++       REQ+N +TSF+DGS +Y S       LR+    +G LR      S+  LLP+ I+  +   ++  +    CF AGD R NE + L  MHT+W+REHNR++ +L  LN HW+ D IY E+RKIVGA +QHITY  +LP +LG + I    QY GY + V+ TI +VFATAA RFGH+ + P   RL+ NF+ I   ++PL  AFF  +++++  GI+P L GL A  S+ V  D+ + A L + LF     +   DL ALNIQRGRDHGL  Y  WR  C +  AE F++   EI     R+ + +VY G     DL+   + E  V G  VGPT  C+L  QF+RLRDGDRFWYE++  F   QL +IK+++L+R++CDN   I  VQR+ F    S    + C+ I  ++L  WK+
Sbjct:    2 YRTMDGTCNNLDNPLWGSAPVPFSRMSDPVYYDDNRLSDPVGFPDQPF--APSLPSPHFISKEFFIHSRRAKPGESGYSHMLMQWGQFLDHDITFT-AESEGAQKCFLPNCDGSSEDYESPCFPIMYPNGDG-----CTMFTRSAAACQNDDKNV-----RPREQLNTVTSFIDGSQIYGSSLATMVNLRNYISKKGYLRT-----SSPDLLPY-IKTTLKPPLNLCQIFGGCFDAGDFRVNEQVALSSMHTMWVREHNRIARQLYELNRHWDDDTIYQEARKIVGAELQHITYTEFLPKILGPDAIP---QYTGYRN-VNPTIMNVFATAAFRFGHSTVRPSFSRLNANFDPIGP-DVPLIDAFFN-NKLVQSTGIEPFLLGLLANFSQDV--DRELAAGLTKHLFQQPESQHGFDLAALNIQRGRDHGLPGYGVWRRECNLTHAEIFEETRDEIRDPVTRQILDRVYNGSVEFADLWVSGLAENPVKGASVGPTFLCILRSQFRRLRDGDRFWYENNGVFGKEQLEEIKKISLSRVMCDNLPGIVSVQRDAFRAPSSSDLRVACARISGIDLTKWKD 553          

Query: 1801 YRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP---CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSE-----GIKRLGQ--YPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYE--SHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPW 3510
            YR+I G CNNL     G+A +PF R+ +P Y + ++ P     G         +AR VS  L +  K  P   +S M M WGQF+DHD+               + C   C     CF I  P  DP        CI   R++      Q  ++      R+QVN  +SF+DGS VY  DP++  +LRD +     LR+        +LLP   +G+  C+    K   PCF AGD R NEN GL  MHTI+ REHNR++ EL+ LN HW+ DK++ E+RKIVGA +QHITYN +LP++          +K L    Y  Y+  V  +I + FA AA RFGH++I  +  R  E ++ I   N+      F P  +    G+D ++RGL    ++ V  D   +  + E+L  +  +  +DL +LNIQRGR+HGL  YN++R+ C +++A +F  F  EI SS I +K+R+VY H  +VDLFAG ++E  V GG +GPT +CL+ +QF RLR GDRFWYE      F   QL  I++++LARI+CDN DN+ ++Q     +   + +   CS I R++L PW
Sbjct:    4 YRTITGVCNNLRYKNWGAANTPFTRVARPAYADMMSKPRAAVGGG-----QLTNARKVSFTLFQ-DKDRPSKRMSHMAMIWGQFIDHDITHGA--------QPNINCENKCGLQGECFGIAVPKDDPHFWAKGVRCIQLKRNVPINIRKQGKLV------RQQVNTKSSFIDGSMVYDDDPVKFEKLRDPS-KRWLLRLKDSPAGGAKLLPPAAKGEF-CRSSDVKRR-PCFMAGDGRVNENPGLSSMHTIFAREHNRIATELKKLNRHWSPDKVFQEARKIVGAQIQHITYNEFLPLIFNETTLIDFDLKLLKPHFYNRYHGRVHPSIFNSFAGAAFRFGHSMIRNVAARFKELYQPINSVNM---NRTFDPLPLYAKKGVDAMMRGLATDPAQQV--DAHFSKFVQEQL--VLPDGMVDLVSLNIQRGREHGLPGYNTFRKLCRLRRASSFLHFRREISSSNI-QKLRKVYKHVDDVDLFAGGIMEIPVKGGSLGPTFTCLVANQFARLRRGDRFWYERPGRTGFTWRQLQSIRKISLARIICDNGDNVRQIQPRALNLRDKRNKLNPCSKISRMSLNPW 554          

Query: 1798 KYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQR---PCIGFSRSIATC-GSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEG-------IKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLR 3306
            +YRSI G CNN  N   G+A SPF R+    Y +G++ P     G        P+AR VS  + +     P   +S M + +GQFLDHD+       S+    D + C  TC     C  I  P  DP        CI   R +     SG  S        REQ+N  +SF+DGS +Y   P   +++R     E  L+V P     K LLP    G   C+  P    +PCF +GD R NEN GLL MHTI++REHNR+S EL+ LN HW  DK+Y E+RKIV A +QHITYN +LP +L +         +++ G Y  YN  V+ +I + FA+AA RFGH+L+  I +R      TI      L    + P  +   GG+D ILRGL    S+  ++D      + E+L     ++A DL A+NIQRGR+HG+  YN++RE CG++   +F +   EI +S I   +R VY H  ++DLF G ++E+ + GG++GPT SCLL  QF  LR
Sbjct:    1 RYRSISGICNNFFNKYWGAAFSPFARVANAAYADGMSAPRAAVGGG-----DLPNARKVSFTVFKEED-RPSTKVSYMSVAFGQFLDHDI-------SHGGQPD-INCTGTCGLQGECIGIPIPADDPHFPTKNVTCIEMRRDLPFIEPSGAVS------PQREQLNIKSSFIDGSQIYGDKPESFSDVR-YPGKEWLLQVQPNPTGGKCLLPPQHGGF--CR-SPHVQSMPCFLSGDMRTNENPGLLSMHTIFLREHNRISSELKKLNQHWTTDKLYLETRKIVIAELQHITYNEFLPTILDTRTRSRYGLVLRKRGFYKNYNAAVNPSIINAFASAAYRFGHSLVRNIAHRFGAENGTI------LMNRTWDPTPIYGKGGVDAILRGLSTDASQ--QADAFFAKAVHEQLVRHTGDLA-DLAAINIQRGREHGIPGYNTYREICGLRNVRSFSELLSEIPNSHI-VNLRNVYEHVDDIDLFVGGMMERPLPGGVLGPTFSCLLGKQFSNLR 480          

Query: 1795 KKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAH-KITPDPNLSAMVMQWGQFLDHDLDF-TPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIG-----FSRSIATCGSGQSSIILGKLHY--REQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGP-VTPSNKRLLPFNI-RGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGL---FAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHD 3339
            +++  ID   NN+ +P  G  + P  RL KP Y +G   P          G ++P  R +S+ +      +     L+   M +GQ + HD DF TP   +N   S+  G            PI  P GDP       G     F RS     +G       KLH   REQVN+IT+FLD S +Y S       LR + + + K + G  +TP+ K++   N+  G  D  +           +GD+R N   GL+ +HT+W REHN + DE+R      + + ++  +R +  A  Q I +  +LP V+GSE   RLG+Y GYN  +   I + F+TAA RFGH+ I   ++RL+EN+E   +G+L L  A+F P RV+++GGI+P++RG+   FA       +D V N      LF   + + LDL +L IQRGRDHGLA YN+ RE  G+ +  +F     EI   E   K  +VY    +VDL+ G + E+ V GG VG T + ++  QFK LRDGDRFWYE+ D
Sbjct:    3 QRFPRIDAVGNNVHHPNLGKPMMPLLRLAKPAYADGFEEP---------SGQARPGPRAISNAIFDQRVDVFSKEGLNEFHMHFGQLVAHDTDFATPY--ANFLTSENFGI-----------PI--PAGDPWFDPHGTGTQMMRFRRSAKLQTTG-------KLHGKPREQVNKITAFLDLSFLYGSQAERTQMLRSMKHGKLKHQEGEMITPNTKQVPNLNLLNGPRDKML----------VSGDNRVNVQPGLIALHTLWSREHNHICDEIRARTPDMDDETLFQHARALTRAKWQKIVWEEYLPTVIGSEEFARLGKYQGYNSSIHVGIFNEFSTAAFRFGHSQIGNTMHRLNENWEMAEQGHLSLRDAYFNPGRVIQEGGIEPLIRGMLKQFAQNVDTKFTDAVRNF-----LFG-TNTMGLDLVSLGIQRGRDHGLADYNAVREAIGLPRRASF----AEITPDENTLKKFEVYPSVDDVDLWVGGLAEEHVEGGCVGETFARIIAMQFKVLRDGDRFWYENPD 480          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEET-LDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP---CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQD  V     + F C+        + W    +    +   +   +  L I  V    EG Y C A +  G++ AS +L++     P     P  ++ E G  V+  CRA G P P +TW+    + V++   GK+ +     +      +   GRY C A +  G      V+T+               +P+ ++  +  +   I+ A   ++ A + T  +L D  + R+  ++ +LFR P     +E A+A +++E+ L     +L +N V   L      T   +  L++P  L +I+ LSGC       +CS  +CFH+KYRS DG CNNL +P  G++L+ F RL+K  Y+NG N P G T  +L +GY  P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C + C ND PCFPI  PP D R  R    C+ F RS   CGSG +S+++  ++ REQ+NQITS++D SNVY S   E+ E+RDL    G LR G +  + K LLPF+     +C  D  ++ +PCF AGDHR NE L L  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP +LG  G+K LG Y  Y+  V++ I + FATAA RFGHTLINPILYRL+E+F+ IP+G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   S Q++N EL E+LF+MAH VALDL A+N+QRGRDHG+  YN +R FC +  A+TFDD   EI +  IREK++++YG P N+DLF   + E  + G  +GPTL CLL  QFK +R+GDRFWYE+   F P+QL+Q+KQ +LAR+LCDN DNI+RVQ +VF +A+    F  C +IP ++L  W++C +  R
Sbjct:  421 ATAFIIVQATPQFTVTPQDQTVLESHTVEFPCEASGYPPPVIAWTRGGSALPLDRRHVVLSSGMLRITRVAAHDEGQYECQAVSPVGTVHASVQLRVEQRVTPVFTNAPRDLTVESGQDVQIPCRAQGQPPPVLTWI---KDGVQVTESGKFHISPEGFLEVRDAGTADAGRYECTARNPIGYQVAGMVLTVT--------------VPAVSREGDTFVSTSIEQAIRDVDSAIESTRRRLFD-GQPRTPGELLALFRYPRDPYTVEQARAGEIFEQTL-----LLIQNHVNRGLMVDTNGTAFRYNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRSHDGTCNNLQHPMWGASLTAFERLLKSVYDNGFNLPRGAT-DRLQNGYRLPLPRLVSTTMIGTETITPDDRYTHMLMQWGQFLDHDLDSTVVALSQSRFSDGQLCAQVCTNDPPCFPIQFPPNDQRQLRTGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQITSYIDASNVYGSSRHESEEIRDLASQRGLLRQGIIQRTGKPLLPFSPGPPTECMRDENESPIPCFLAGDHRANEQLALTAMHTVWFREHNRIATELLRLNPHWDGDTIYHEARKIVGAQMQHITYSHWLPKILGEVGMKMLGPYKSYDPNVNAGIFNAFATAAFRFGHTLINPILYRLNEHFQPIPQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVPGKMRVSTQLLNTELTERLFSMAHAVALDLAAMNVQRGRDHGIPPYNDYRTFCNLSSAQTFDDLKNEIKNPIIREKLQRLYGTPQNIDLFPALMAEDIIPGSRLGPTLMCLLTTQFKLVRNGDRFWYENPGVFTPSQLTQLKQASLARVLCDNGDNITRVQSDVFMVAELPHGFGSCDDIPHIDLRMWQDCCEDCR 1318          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSIS------------------------KIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISAS-AKLKI--APNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C  +C C   TV C     + +P + +   T L L  N I                         +I    F++ ++L ++ L  N+I  ++  A  G + LE LYL  N IE L  + FS      +L    N   + +P +   L  +KRL L  N L C CE+ + A  L+     G     + C  P  ++ + +  +   EL        EL P+    PQD  V +G+ + F C+ E   + ++ W    N      D+  N L   +  L I++  E  +G+Y C A N  G +  S   L+   AP +  ++++ P +     G  V   C A G P P ++  W K ++  L  + +  I     L I+N+ +++  G+Y C+AS+   +   +A I +
Sbjct:   34 CPSRCLCFRTTVRCMHLNLEAVPAV-SPLTTILDLRFNKIKDLQPASFSRLKNLNTLLLNNNQIRRISRGAFEDLENLKYLYLYKNEIQSIDRQAFKGLVSLEQLYLHFNNIESLEPESFSHLPKLERLFLHNNRITQLVPGTFSHLSAMKRLRLDSNALNCNCEVLWLADLLKLYAESGNAQAAATCDHPSRLQGRSVATLTAEEL------NCEL-PRITSEPQDVDVTLGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDSRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTSQVTLRYFGAPTRPSFVIQ-PQNTEVLVGESVTLECSATGQPQPRVS--WTKGDRTPLPNDPRITITTSGGLYIQNVQQAD-GGQYTCFASNNVDTIHATAFIIV 427          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEET-LDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP---CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQD  V     + F C+        + W    +    +   +   +  L I  V    EG Y C A +  G++ AS +L++     P     P  ++ E G  V+  CRA G P P +TW+    + V++   GK+ +     +      +   GRY C A +  G      V+T+               +P+ ++  +  +   I+ A   ++ A + T  +L D  + R+  ++ +LFR P     +E A+A +++E+ L     +L +N V   L      T   +  L++P  L +I+ LSGC       +CS  +CFH+KYRS DG CNNL +P  G++L+ F RL+K  Y+NG N P G T  +L +GY  P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C + C ND PCFPI  PP D R  R    C+ F RS   CGSG +S+++  ++ REQ+NQITS++D SNVY S   E+ E+RDL    G LR G +  + K LLPF+     +C  D  ++ +PCF AGDHR NE L L  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP +LG  G+K LG Y  Y+  V++ I + FATAA RFGHTLINPILYRL+E+F+ IP+G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   S Q++N EL E+LF+MAH VALDL A+N+QRGRDHG+  YN +R FC +  A+TFDD   EI +  IREK++++YG P N+DLF   + E  + G  +GPTL CLL  QFK +R+GDRFWYE+   F P+QL+Q+KQ +LAR+LCDN DNI+RVQ +VF +A+    F  C +IP ++L  W++C +  R
Sbjct:  373 ATAFIIVQATPQFTVTPQDQTVLESHTVEFPCEASGYPPPVIAWTRGGSALPLDRRHVVLSSGMLRITRVAAHDEGQYECQAVSPVGTVHASVQLRVEQRVTPVFTNAPRDLTVESGQDVQIPCRAQGQPPPVLTWI---KDGVQVTESGKFHISPEGFLEVRDAGTADAGRYECTARNPIGYQVAGMVLTVT--------------VPAVSREGDTFVSTSIEQAIRDVDSAIESTRRRLFD-GQPRTPGELLALFRYPRDPYTVEQARAGEIFEQTL-----LLIQNHVNRGLMVDTNGTAFRYNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRSHDGTCNNLQHPMWGASLTAFERLLKSVYDNGFNLPRGAT-DRLQNGYRLPLPRLVSTTMIGTETITPDDRYTHMLMQWGQFLDHDLDSTVVALSQSRFSDGQLCAQVCTNDPPCFPIQFPPNDQRQLRTGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQITSYIDASNVYGSSRHESEEIRDLASQRGLLRQGIIQRTGKPLLPFSPGPPTECMRDENESPIPCFLAGDHRANEQLALTAMHTVWFREHNRIATELLRLNPHWDGDTIYHEARKIVGAQMQHITYSHWLPKILGEVGMKMLGPYKSYDPNVNAGIFNAFATAAFRFGHTLINPILYRLNEHFQPIPQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVPGKMRVSTQLLNTELTERLFSMAHAVALDLAAMNVQRGRDHGIPPYNDYRTFCNLSSAQTFDDLKNEIKNPIIREKLQRLYGTPQNIDLFPALMAEDIIPGSRLGPTLMCLLTTQFKLVRNGDRFWYENPGVFTPSQLTQLKQASLARVLCDNGDNITRVQSDVFMVAELPHGFGSCDDIPHIDLRMWQDCCEDCR 1270          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISAS-AKLKI--APNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C  +C C   TV C     + +P + +   T L L  N I  +    F   K+L  + L+ N+I  +   A      L+ L+L NN I  L                        +P +   L  +KRL L  N L C CE+ + A  L+     G     + C  P  ++ + +  +   EL        EL P+    PQD  V +G+ + F C+ E   + ++ W    N      D+  N L   +  L I++  E  +G+Y C A N  G +  S   L+   AP +  ++++ P +     G  V   C A G P P ++  W K ++  L  + +  I     L I+N+ +++  G+Y C+AS+   +   +A I +
Sbjct:   34 CPSRCLCFRTTVRCMHLNLEAVPAV-SPLTTILDLRFNKIKDLQPASFSRLKNLNTLLLNNNQIRRISRGAFEDLENLKYLFLHNNRITQL------------------------VPGTFSHLSAMKRLRLDSNALNCNCEVLWLADLLKLYAESGNAQAAATCDHPSRLQGRSVATLTAEEL------NCEL-PRITSEPQDVDVTLGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDSRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTSQVTLRYFGAPTRPSFVIQ-PQNTEVLVGESVTLECSATGQPQPRVS--WTKGDRTPLPNDPRITITTSGGLYIQNVQQAD-GGQYTCFASNNVDTIHATAFIIV 379          

Query:  787 SNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFN--SLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQP-SLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEET-LDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRP---CIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSR 3534
            + +F   +  P+F   PQD  V     + F C+        + W    +    +   +   +  L I  V    EG Y C A +  G++ AS +L++     P     P  ++ E G  V+  CRA G P P +TW+    + V++   GK+ +     +      +   GRY C A +  G      V+T+               +P+ ++  +  +   I+ A   ++ A + T  +L D  + R+  ++ +LFR P     +E A+A +++E+ L     +L +N V   L      T   +  L++P  L +I+ LSGC       +CS  +CFH+KYRS DG CNNL +P  G++L+ F RL+K  Y+NG N P G T  +L +GY  P  RLVS+ ++    ITPD   + M+MQWGQFLDHDLD T V  S SRFSDG  C + C ND PCFPI  PP D R  R    C+ F RS   CGSG +S+++  ++ REQ+NQITS++D SNVY S   E+ E+RDL    G LR G +  + K LLPF+     +C  D  ++ +PCF AGDHR NE L L  MHT+W REHNR++ EL  LN HW+GD IY+E+RKIVGA MQHITY+ WLP +LG  G+K LG Y  Y+  V++ I + FATAA RFGHTLINPILYRL+E+F+ IP+G++ LHKAFF+P R++ +GGIDP+LRGLF +  K   S Q++N EL E+LF+MAH VALDL A+N+QRGRDHG+  YN +R FC +  A+TFDD   EI +  IREK++++YG P N+DLF   + E  + G  +GPTL CLL  QFK +R+GDRFWYE+   F P+QL+Q+KQ +LAR+LCDN DNI+RVQ +VF +A+    F  C +IP ++L  W++C +  R
Sbjct:  397 ATAFIIVQATPQFTVTPQDQTVLESHTVEFPCEASGYPPPVIAWTRGGSALPLDRRHVVLSSGMLRITRVAAHDEGQYECQAVSPVGTVHASVQLRVEQRVTPVFTNAPRDLTVESGQDVQIPCRAQGQPPPVLTWI---KDGVQVTESGKFHISPEGFLEVRDAGTADAGRYECTARNPIGYQVAGMVLTVT--------------VPAVSREGDTFVSTSIEQAIRDVDSAIESTRRRLFD-GQPRTPGELLALFRYPRDPYTVEQARAGEIFEQTL-----LLIQNHVNRGLMVDTNGTAFRYNDLVSPRFLDMIANLSGCTAHRRINNCSD-ICFHQKYRSHDGTCNNLQHPMWGASLTAFERLLKSVYDNGFNLPRGAT-DRLQNGYRLPLPRLVSTTMIGTETITPDDRYTHMLMQWGQFLDHDLDSTVVALSQSRFSDGQLCAQVCTNDPPCFPIQFPPNDQRQLRTGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQITSYIDASNVYGSSRHESEEIRDLASQRGLLRQGIIQRTGKPLLPFSPGPPTECMRDENESPIPCFLAGDHRANEQLALTAMHTVWFREHNRIATELLRLNPHWDGDTIYHEARKIVGAQMQHITYSHWLPKILGEVGMKMLGPYKSYDPNVNAGIFNAFATAAFRFGHTLINPILYRLNEHFQPIPQGHISLHKAFFSPFRIVNEGGIDPLLRGLFGVPGKMRVSTQLLNTELTERLFSMAHAVALDLAAMNVQRGRDHGIPPYNDYRTFCNLSSAQTFDDLKNEIKNPIIREKLQRLYGTPQNIDLFPALMAEDIIPGSRLGPTLMCLLTTQFKLVRNGDRFWYENPGVFTPSQLTQLKQASLARVLCDNGDNITRVQSDVFMVAELPHGFGSCDDIPHIDLRMWQDCCEDCR 1294          

Query:  244 CLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLR---RIGLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFN------DTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISAS-AKLKI--APNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKY-IVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            C  +C C   TV C     + +P + +   T L L  N I  +    F   K+L  + L+ N+I  +   A      L+ LYL  N IE L  + FS      +L    N   + +P +   L  +KRL L  N L C CE+ + A  L+     G     + C  P  ++ + +  +   EL        EL P+    PQD  V +G+ + F C+ E   + ++ W    N      D+  N L   +  L I++  E  +G+Y C A N  G +  S   L+   AP +  ++++ P +     G  V   C A G P P ++  W K ++  L  + +  I     L I+N+ +++  G+Y C+AS+   +   +A I +
Sbjct:   34 CPSRCLCFRTTVRCMHLNLEAVPAV-SPLTTILDLRFNKIKDLQPASFSRLKNLNTLLLNNNQIRRISRGAFEDLENLKYLYLHFNNIESLEPESFSHLPKLERLFLHNNRITQLVPGTFSHLSAMKRLRLDSNALNCNCEVLWLADLLKLYAESGNAQAAATCDHPSRLQGRSVATLTAEEL------NCEL-PRITSEPQDVDVTLGNTVYFTCRAEGNPKPQIIWLRNNNALNMRDDSRLNLL--EDGTLMIQDTRETDQGVYQCMAKNVAGEVKTSQVTLRYFGAPTRPSFVIQ-PQNTEVLVGESVTLECSATGQPQPRVS--WTKGDRTPLPNDPRITITTSGGLYIQNVQQAD-GGQYTCFASNNVDTIHATAFIIV 403          

Query: 1435 LYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQS------LFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHK--ITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRV-QRP--CIGFSRSIATCGSGQSSIILG-KLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQI------DPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIK-RLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPE-GNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKE 3516
            L +  K+A++ ++ A+K + E+    + +R R+D+        L +QP        +++D  E+ L     +LRE   ++     Y  +L+ T LL+PE L  +++L+GC+       C Q L    KYR+    CNNL NPR G++ +PF R +  EY++GI+ P GW   + ++ +  P  R VS+ +L      +  D   + MV  +GQ+ DHDL FTP   S   FS+GL C+E+C    PC PI  PPGDPR+  RP  CI   RS   CG+G S+   G + + REQ+N +T+FLD   VY S+   A  LR+L+ D G +RV      N R LLPF+      C        D     VPCF AGD R +EN+ L  +HT+++REHNRL+  L+ LN HW+ + +Y E+RKI+GA  Q   +  +LP ++G + ++ +LG+YPGYN  +D +I++VFATAA RF H  I P+L RLD N    P+  ++PL++AFF P RV+ +GGIDP+LRGL    +K    D ++   L E+LF     +ALDLG+LN+QR RDHG+  YN+WR FCG+ + +     +  + ++++  ++ ++YG P N+D++ G V E  V GG VGP  +CL+  QF+R+R GDR WYE    F P+Q + ++ V+++RI+CDN+  I+ V  + + +  S    + CS+I  LNL  W+E
Sbjct:   30 LQQCFKEAKTIVDDAYKYSREE----SLKRVRTDVVKPHDALRLMKQPRGDTRSAVRSADYMEQTLR----LLRERVHRV-----YRRSLNATDLLSPEDLEKLAKLTGCEARVRLPQC-QILQNINKYRTATSICNNLNNPRLGASNTPFTRWLPAEYDDGISQPKGWNRNRTFNNFLLPLVRQVSNNILSTTDAGVVNDTEYTHMVTLFGQWNDHDLTFTPFSPSIRSFSNGLNCDESCEQSEPCTPIPIPPGDPRLPSRPDSCIPAFRSAPVCGTGYSAYNFGGEPNKREQINALTAFLDLGQVYGSEEKLALFLRNLSSDAGLMRVNTEFRDNGRELLPFHPMQVQMCATRRRITNDTNAKEVPCFIAGDGRVDENIALTSIHTLFVREHNRLARGLKNLNPHWDSETLYQEARKIMGAYTQTFVFRDYLPHIVGDDAMRNQLGRYPGYNPNIDPSIANVFATAAYRFAHLAIQPVLSRLDANNNEHPQFPSVPLYEAFFTPWRVVFEGGIDPLLRGLIIRPAKLNTQDHMLVNALRERLFQFVQHLALDLGSLNMQRSRDHGIPGYNAWRRFCGLSQPQNQAQLAQVLGNNDLARRLLELYGTPDNIDIWLGGVAEPFVRGGRVGPLFACLIATQFQRIRQGDRLWYEKPGVFTPSQRAALRSVSMSRIICDNT-GIAAVPMDAYRIVSSSNRLVRCSSIAGLNLAAWRE 729          

Query: 1435 LYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRS--DIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRA--HKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQ---RPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKR-LLPFNIRGQVDCQI------DPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGI-KRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLP---LHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPW 3510
            + + + +A++ ++ A+  +  K  D  ++   S   +  L +QPS  + E  +A+D  +  L  L G L + +         + +++ T L+T E L +I++L+GC        C       K YR+    CNNL NPR GS+  PF R +  EYE+ + +P GWT+    + +  P  R VS+R+L      +  DP  S +V  +GQ+ DHDL FTP   S   F++ + C  +C    PCFPI  P  D R Q   + C+ FSRS   CGSG +  I G    R Q+N +TSF+D   VY SD  +A +LRDL+ +EG ++V P    N R LLPF       C+       DP    + CF AGD R+NEN+GL  +HT+ +REHN L+  L  LN +W+G+++Y E+RKI+G  MQ ITY  +L  +LG E + K+L  YPGY++ VD +I++VFATAA RF H ++ P ++RL+EN+E     + P   LH+  F P R+  +GG+DPILRGL    +K    + ++  EL  +LF  + ++A+DLG+LN+QRGRDHGL  YN WR FCG+ + +  ++ +  + ++++ +++  +YG   N+D++ G V E  V+GG VGP  +CL+  QFKR+R GDRFW+E++  F  AQ   ++  +LARI+CDN+  I+ V    F        +  C ++P  +L PW
Sbjct:   30 IVKAVAEAKANVDAAYTYSRRKSIDRVKRSGASPGSVIPLLKQPSGLSREAVRAADYMQNTLSLLRGALEKRQ---------KRSINATDLITVEDLNVIAKLTGCAAQIRPPSCKD---IPKSYRTAASSCNNLKNPRWGSSNIPFLRWLPAEYEDDLTSPKGWTSDLRVNYHLIPLVREVSNRILATANEDVESDPLYSHLVTIFGQWTDHDLTFTPHSPSIVSFNNNISCETSCARTEPCFPIEIPSNDERFQEDPKECLPFSRSAPACGSGNTGHIFGASTLRHQMNTLTSFIDAGQVYGSDEAKAQKLRDLSTEEGLMKVNPEFDDNGRALLPFTADNAKMCKTRANITKDPNARELECFFAGDDRSNENIGLASLHTLMVREHNHLARALANLNPNWDGNRLYQEARKIMGGYMQVITYRDYLRHILGPEVMSKQLSTYPGYDENVDPSIANVFATAAYRFAHLMVQPFIFRLNENYEN--HADYPTELLHRTMFTPWRIAFEGGLDPILRGLVGRPAKLNTQNHMLTEELRNRLFKFSVDLAMDLGSLNMQRGRDHGLPRYNKWRGFCGLSQPQNLEELATVLNNTDLAQRLLDLYGTADNIDVWLGGVAEPFVAGGRVGPLFACLISTQFKRIRQGDRFWWENNGVFTCAQRRSLRDASLARIICDNT-GITEVPNQPFQYRPRGSGYFQCKDLPAFDLKPW 724          

Query:  172 MNFFIVIIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFXXXXXXXXXXXXANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAGNLRRIGLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSFEASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYNAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWREFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQCSSNISNLEERIKSLEDKMLHLNQKN 3711
            MNFFIVIIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFSDHSDSLKLLSLANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFA NLRRIGLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSF+ASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSR+KLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITY+AWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWR+FCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQCSSNISNLEERIKSLEDKMLHLNQKN
Sbjct:    1 MNFFIVIIFLGSLNFLSVSTTGQECLPQCRCTEKTVTCRRGGFQMIPEIGNKRLTYLSLPGNSISKIIANQFKEFKDLIHVDLSFNKISLVEENALYGPIFLETLYLKNNLIEYLPEQIFSDHSDSLKLLSLANNRLKTLPISLEKLINVKRLELYGNMLYCGCELRYFAANLRRIGLDFQKSQCQSPMNVKNQFLEEVKFNELCSNSFQASELAPKFIERPQDAYVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRDKLKNEQLYEIIKDAQSKINVAFKKTAEKLRDPNRQRSRSDIQSLFRQPSLAALELAKASDVYEKVLDDLTGILRENKVKLNLTTAYEETLDFTTLLTPEQLAIISQLSGCQRSTEELHCSQQLCFHKKYRSIDGKCNNLINPRRGSALSPFYRLMKPEYENGINTPIGWTAGKLYHGYSKPSARLVSSRLLRAHKITPDPNLSAMVMQWGQFLDHDLDFTPVDASNSRFSDGLGCNETCVNDSPCFPILTPPGDPRVQRPCIGFSRSIATCGSGQSSIILGKLHYREQVNQITSFLDGSNVYSSDPLEATELRDLTYDEGKLRVGPVTPSNKRLLPFNIRGQVDCQIDPAKAHVPCFKAGDHRNNENLGLLVMHTIWMREHNRLSDELRGLNNHWNGDKIYYESRKIVGAMMQHITYHAWLPIVLGSEGIKRLGQYPGYNDMVDSTISSVFATAAMRFGHTLINPILYRLDENFETIPEGNLPLHKAFFAPDRVMEDGGIDPILRGLFAIGSKAVKSDQVMNAELIEKLFAMAHEVALDLGALNIQRGRDHGLASYNSWRKFCGMKKAETFDDFSGEIVSSEIREKMRQVYGHPGNVDLFAGAVLEQKVSGGLVGPTLSCLLIDQFKRLRDGDRFWYESHDQFEPAQLSQIKQVTLARILCDNSDNISRVQRNVFFMAKSKLEFIDCSNIPRLNLIPWKECYDPSRLTPEDQVPGLSPSRSRRSTNEFQDQNCKSKTNQCSSNISNLEERIKSLEDKMLHLNQKN 1180          

Query:  817 PKFIERPQDAYVAVGDKIRFACQVENINETKVEWH---FQFNDTTFNSLYWRNQW-LFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL---ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVI 1350
            P F   P+   V V   I F C V   +   ++W+      ND + +     N   + I  V     G Y+C A N+ G      KL +     P  +E P +I    G +V   C A G P P++   W  +NQ  L   +   + IV +N  +  +   S+  G+Y CYASS  G ++  A +
Sbjct:  186 PIFHILPKHLQVMVSSHILFPCLVIGDSPMFIQWYKLGSGKNDISLSRTALSNNCSMIINNVKLEDSGAYVCRARNSGGITEIIYKLSVI--SFPSFIETPENIRTTVGEKVALRCSASGVPAPKV--FWWHTNQYFLSDIDNNNRIIVFENGTLSISSVRSKDSGKYYCYASSFVGVSRSEATL 366          

Query:  817 PKFIERPQDAYVAVGDKIRFACQVENINETKVEWHF--QFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITW-----LWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSK 1368
            P+F   P +  V V +   F C  +   +  + W    Q    +  +    N+ + I +V     G YIC ASN+ G + A AKL +     P  +E P +     G    F+CR  G P P I W      ++   +    +E   + +  +L I  +  S+  G+Y C ASS  G  + SA + +I ++
Sbjct:  214 PQFKIAPSNIEVKVNEAAVFPCVADGDPKPTIVWRRDNQKKIPSSRATLIDNKGMQISKVQLTDMGNYICHASNSAGHLEAYAKLSVV--STPGFIETPDNQKVRVGDTAIFNCRVTGSPQPTIIWSHNGDHFIADEENSRRSERIQVDKLGSLTINPVKISD-SGKYECKASSYIGKIQSSASLHVIDAQ 401          

Query:  817 PKFIERPQDAYVAVGDKIRFACQVENINETKVEWH--------FQFNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKG-SISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCR-AHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSKLPSRNKLKNEQLYEIIKDAQSKINVAFKKTAEK 1500
            P   E P   +     ++   C  +      + W+        ++    T N L   N+ LF+  +    EG+Y C ASN  G +IS +A + IA   K  I  GP S +A  G  V   C+   G P P + W +   N + +    K I+   NL I+  T  +  GRY C A + +     ++ +  +R K +  +   + ++    K+    ++  + D   K  + +++  +K
Sbjct:   26 PIISEHPASTHGLSLQRVSLRCSAKGDPMPNIIWYKDGQVVESYRDKPATSNRLVKDNELLFM-HLDTQDEGVYYCNASNIHGWTISNNASVLIAFLNKDII--GPESKTASVGETVLMECKPPKGVPKPTVIWKF-NGNAIEVNKRIK-ILDNGNLRIDKATRKD-SGRYNCLAKNFADERDSTSALLTVRQKPQFKIAPSNIEV----KVNEAAVFPCVADGDPKPTIVWRRDNQK 253          

Query:  820 KFIERPQDAYVAVGDKIRFACQV-ENINETKVEWHFQFNDTTFNSLY--WRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRS 1365
            K I  P+    +VG+ +   C+  + + +  V W F  N    N       N  L I +      G Y C A N      +++ L +   QKP     P++I  +      F C A G P P I  +W + NQ ++ +    ++    + I  +  +++ G Y+C+AS+ +G  +  A ++++ +
Sbjct:  123 KDIIGPESKTASVGETVLMECKPPKGVPKPTVIWKFNGNAIEVNKRIKILDNGNLRIDKATRKDSGRYNCLAKNFADERDSTSAL-LTVRQKPQFKIAPSNIEVKVNEAAVFPCVADGDPKPTI--VWRRDNQKKIPSSRATLIDNKGMQISKVQLTDM-GNYICHASNSAGHLEAYAKLSVVST 303          

Query:  787 SNSFEASELAPKFIERPQDA-YVAVGDKIRFACQVENINETKVEWHFQFNDTTFNSL-----YWRNQWLFIKEVHEFHEGIYICTASNNKG--SISASAKLKIAPNQ-KPYIVEGPASISAEKGSRVEFSCRA-HGYPVPEITWLWVKSNQVRL-ETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            S S +   ++P  IE P+ +  V VG+++   C VE     ++ W+   N+   +++     +   Q L I  V + H G+Y C A+N+ G   I  + ++ + P   +P   E    ++    + ++  C+   G P P ITW   + N + L + +  Y    + L I N  + E EG   C A +++G  +++  IT+
Sbjct: 2512 SKSVDVVIISPPKIESPKKSIMVRVGEQVLLPCIVEGTRPFRIHWYTPGNNQISSTILGEYQFLSEQGLIIDRVRKDHSGVYRCVANNDAGYQEIRITLEVLVQPKIFRPTETETTGVLN----TVLQMQCKILEGIPQPVITW---ERNGITLSKVKNYYTTTDSGLFIFNSLKIEDEGSLTCIAKNVAGEDRLTFQITV 2705          

Query:  859 GDKIRFACQVENINETKVEWHFQFNDTTFNSLYWRNQW---LFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWL--WVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            GD+    C    + + K+ W F  +  T +     N+    L I  + +  +G ++C A+NN GS   S  L I     P I +   +I    G  +   C+  G+P P + WL        + +    +Y + ++N +I      E +  Y+C A +  G  + S  I +
Sbjct:  741 GDQQTVRCSANGVPQPKITWEFNGSPVTIDGNIIINETIGTLDINRIEKNMKGQWVCVATNNAGSSRKSFNLDIGFG--PRIKDFVTNIDGSYGENITIRCQVEGHPPPRVKWLRGIAGGYNIPIALGDRYFINQDNSLIIKGLSMEDQSAYICDAQNQHGKVQESVQIRI 909          

Query:  952 LYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKIAPNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYIVRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEESSK 1401
            LY  +  L I +      GIY C ASN+ G   A  ++ +     P     P +ISA  G  +   C A GYP+P I+W   K+ ++      K +++  +L I  + + E  G Y C ASS  G      +   ++     +  +E SK
Sbjct: 2935 LYINDFNLIINQAKSKDTGIYQCIASNSAGE--AQGQVHLLVKSPPVFTLLPGNISANLGEVLILPCAAEGYPIPTISWY--KNKKLIKYDFVKSLIKNGSLRIIGV-QKEHSGVYFCVASSNQGEVHSQPIYLTVQIPGGWSAWQEWSK 3079          

Query:  796 FEASELAPKFIERPQDAYVAVGDK--IRFACQVENINET-KVEWHFQFNDTTFNSLYWRNQWLFIKEV------HEFHEGIYICTASNNKGSISASAKLKI--APNQKPYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRLETEGKYI----VRKNNLVIENITESEVEGRYVCYASSLSGSAKVSAVITLIRSKNELNLNEES 1395
            F+ S  AP  I +   +   +G K  +   C + + N + K+EW+   N      +  R +    K +      +E   G Y C A+N   S S   ++ I  AP      +     I  ++G ++  +C+  G+P P   W W KS+ + L+     I    + KN+L+I  +  SE++G Y C  +++ GSAK+S  + ++ S   +  N++S
Sbjct: 1092 FKVSVKAPPQISKEGISDYEIGSKENVELNCIITSGNPSPKIEWYK--NGQPLVEIPGRVEIAGQKNILKVYGKNEDETGSYECKATNEVSSDSRFFQITILVAPKASDSKM---IKIYTKEGEKLTLNCKIDGFPTPTKKWSW-KSSILDLQRNPFGITNSPIDKNDLLITQM-RSELQGIYTCDGTNVGGSAKMSYDVIILESPKIIQFNDKS 1299          

Query:  805 SELAPKFI-ERPQDAYVAVGDKIRFACQVENINETKVEWHFQ------------FNDTTFNSLYWRNQWLFIKEVHEFHEGIYICTASNNKGSISASAKLKI---------APNQK--PYIVEGPASISAEKGSRVEFSCRAHGYPVPEITWLWVKSNQVRL-ETEGKYIVRKNN----LVIENITESEVEGRYVCYASSLSGSAKVSAVITL 1356
            S   PKF+ E  +   V  GD ++   +V+      VEW+              F D    SLY       I E      G Y   A N  GS+ +SA L +          P  K  P I++ P S+      +  F  +  G PVPE++W     N + + E+E   I+  NN    L+I ++ E++  G Y   A ++ G A+ S  +T+
Sbjct: 5044 STYPPKFVRELEKSIQVKEGDSVKLLAEVDGYPTPVVEWYKNGIVIEKNPDYKLFRDGNVVSLY-------IHETFTDDTGEYNLIARNPFGSVKSSAHLTVTITPESADNVPQSKQIPRIIQEPKSVKLNLNKKAVFEAKVIGSPVPEVSWY---HNDIFIEESENVSIIYSNNEYTKLIINSVKETDA-GTYTVKAVNIVGEAQFSTSLTV 5245