Cullin

Overview
NameCullin
Smed IDSMED30031169
Length (bp)2575
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cullin (SMED30031169) t-SNE clustered cells

Violin plots show distribution of expression levels for Cullin (SMED30031169) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cullin (SMED30031169) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cullin (SMED30031169) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031169

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30031169h1SMcG0002986 dd_Smed_v4_3730_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
whole organismSMED30031169h1SMcG0002986 dd_Smed_v6_3730_1_1dd_Smed_v6PMID:29291974
Strand et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cullin vs. Ensembl Human
Match: CUL4A (cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554])

HSP 1 Score: 498.819 bits (1283), Expect = 1.127e-164
Identity = 304/729 (41.70%), Postives = 446/729 (61.18%), Query Frame = 3 
Query:  177 NEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHV-SECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFN---GLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            N  +  W  L +A+  + +++ I  NLE LY+ VE+  + +++  ++  LRQ C  HV ++  P  +++DS D V FL  I T W ++C ++ +IRSI LF+DR +   NS+L S WDM ++L+R   I+  ++ +K I   L  I  +R G + D SL +++  M  DL +Y+  +E K+L+E    Y+ E +R ++E    +YL +V+ RL+EE +R   YL   S +  L   +   +L  HL  +L+ G +H+++ N +  L  +Y L       S    G   L  ++ EY+   GT IV NP    EKDK M Q+ LD K  +D V+E CF+ +  F   +++ FE F+N RPNKPAE +AK +DSKLR+GNK  T+E +E  +DK+M LFRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F     +QN  D       I++ VN++    WP+    ++   P+ MI +Q  F AFY   H+GRKL+++ +LG  +++  F +G+KE QVS FQ +VLL FN   G      ++ +++ A GI+   L++TL SL+ GK  RVL K P   +V D D F FN  F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV+++  +L+FP+K  D+KKRIE LI+RDY+ RD+ N + YHYVA
Sbjct:   57 NYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILP--FREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLD-HSTQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLF------SRVRGGQQALLQHWSEYIKTFGTAIVINP----EKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF--KQHMQNQSDSG----PIDLTVNILTMGYWPTYTPMEVHLTPE-MIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDG-----FSFEEIKMATGIEDSELRRTLQSLACGKA-RVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA 759
[Close]
BLAST of Cullin vs. Ensembl Human
Match: CUL4B (cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555])

HSP 1 Score: 491.115 bits (1263), Expect = 3.795e-162
Identity = 303/729 (41.56%), Postives = 452/729 (62.00%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+     + +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N++++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++++A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:   11 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIKAQIHQ-FREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EEIKQATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 717
[Close]
BLAST of Cullin vs. Ensembl Human
Match: CUL4B (cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555])

HSP 1 Score: 491.886 bits (1265), Expect = 2.731e-160
Identity = 303/729 (41.56%), Postives = 452/729 (62.00%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N++++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++++A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  189 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EEIKQATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895
[Close]
BLAST of Cullin vs. Ensembl Human
Match: CUL4B (cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555])

HSP 1 Score: 491.886 bits (1265), Expect = 3.796e-160
Identity = 303/729 (41.56%), Postives = 452/729 (62.00%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N++++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++++A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  194 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EEIKQATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 900
[Close]
BLAST of Cullin vs. Ensembl Human
Match: CUL4B (cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555])

HSP 1 Score: 491.886 bits (1265), Expect = 4.375e-160
Identity = 303/729 (41.56%), Postives = 452/729 (62.00%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N++++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++++A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  207 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EEIKQATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913
[Close]
BLAST of Cullin vs. Ensembl Celegans
Match: cul-4 (Cullin-4 [Source:UniProtKB/Swiss-Prot;Acc:Q17392])

HSP 1 Score: 253.447 bits (646), Expect = 8.798e-72
Identity = 204/752 (27.13%), Postives = 382/752 (50.80%), Query Frame = 3 
Query:  192 NWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTEI-FNNLRQLCLR---------HVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDR-KFWSNNSSLMSFWDMAMQLWRDMYITGPLINKE---------IVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYL-DEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSG-TLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKG---DMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEA-MELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYF-PKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLN--------KRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            +W +L   +  I  +    T LE L+  V S   +  +++ ++ L  + ++         +  E  P L +D+   E +L      W  Y +KI +IR+I L +DR    + ++ ++  W+  MQ+++  +   P I KE         + + +++I  QR  + S L   +++  M   + + + F   K+L  + R +Y+ E   K+ +++  DY+ Y   +++  ++  ++     S    ++  + N +++  + E+L   F+ ++++++I  +  ++NL +       +      +R  F +Y+ K G  LI   P++D      +    L  K  +D ++   FK     +   + + D FE+F+N + ++ AE ++K   + L S NKN++++  ++ ++D+ + LFR++ GKDVFEA+Y + LAKRL + +SA VD EK +L KLK ECG  +T K+E MF D+D S+   + F       N   + MNK        VI    WP+    + +NIP+ M D    +  FY+  H  R +++   L + ++   F P  +KEL  + +Q ++LL FN   E +     +E    ++ + +K  L  L      +VL         K+  + +   ++ F  N  F  K  +++  Q+  K   EE +  +E+V +DRQ  +D  +VR+MK+ + + H  L+T++L++LRFP+  +DIKKR+E LIER+YI+RD   +S Y+YVA
Sbjct:  121 DWAVLSDNVFAILEDRKTVTTLEGLFSKVRSVCDKNQSKVLYDRLVAIVVQFAKSLKESLNAVEQVP-LAEDNC--EQYLEKFGQIWQAYPVKINLIRNIFLHLDRIALGATDTEILPLWECFMQIFQKTFF--PNIFKEFKATKLFNALYMAMQKIM-QRYPVDSPL---RSLVDMLQTVHVSEEF--AKFLISQLREHYNNERIDKVPKMNCNDYMEYCEDQINRYSQLVKVNFDEPSALKDVQATVTNCLIQQAIPEILTHDFDDLIDSDNISDIGRMFNLCRQCVGGEDE------VRTQFSKYLKKRGEKLIATCPDED------LVSELLAFKKKVDFIMTGSFKSANDPVKMRQCLSDAFESFVNKQVDRSAELISKHFHTLLHSSNKNVSDDTTLDQMVDEAIVLFRYLRGKDVFEAYYKRGLAKRLFLERSASVDAEKMVLCKLKTECGSAFTYKLEGMFKDMDASENYGRLF-------NQYLEHMNKEKANFTARVITPEYWPTYDTYE-INIPKEMRDTLTDYQDFYRVQHGNRNVKWHHGLASAVISASFRPGCKKELIATMYQTVILLLFNK-CETWTVAEIVEHTKILEIEVVKNVLALLGGRDKPKVLQRVEGGGSEKKEGTVENLKNEKFVVNSKFTEKRCRVRIAQVNIKTAVEETKEVKEEVNSDRQYKIDAAVVRIMKARKQLNHQTLMTELLQQLRFPVSTADIKKRLESLIEREYISRDPEEASSYNYVA 840
[Close]
BLAST of Cullin vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 247.284 bits (630), Expect = 5.269e-70
Identity = 221/788 (28.05%), Postives = 384/788 (48.73%), Query Frame = 3 
Query:  126 AQLPKKINPFLELKTVKNEFET-NWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTD-YLVYVNTRLDEENERSQMYLS--GDSIRIQLRDQLVNIILKPHLDELL---KSGFNHMMENNDIFXXXXXXXX-XXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYF---PKG------------------------RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKG-QRVL---NKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
             Q   +I PF+   T+  ++ T  W +L++AI +I   +    + E LYR   +     + E ++N L+ +   H++    ++ +  ++   FL  +  SW ++ + + +IR I++++DR + + N+ ++  +++ +  +R   +    I   I    L+ I   R     +    K    M I L +     Y+  +E   L E   YY    +  L   ++   YL  V   + +E  R+  YL    ++  +Q+ D   ++++  H+  ++     G   M+E+  I  L  ++ +  ++ +S +    G+  L     EY+ ++G+ IV+N  D ++         L LK +  S++   F  D  F    +  FE FLN+    P E++A ++D  LRSG K +++  M+  +D VM LFR++  KDVFE ++ + LAKRLL+ KS   D EKA+L KLK ECG  +T+K+E MF D +    L+  F D    Q        K++I++++ V+    WP++  + ++ +PQ +      F+ +Y   H GRKL     LG   V+  F   PK                          K LQV+  Q ++LLQFN      ++   L   + I    LK+ L SL++GK  QR+L   NK   +  +SD+  F  N+NF  KLT++K   +  K   E E + T ++V  DR+  ++  IVR+MK+ + + H  LV +V ++LR     S   IK+RIE LIER+Y+ RD+ +   Y Y+A
Sbjct:    9 GQQKMRIRPFM--ATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGS-FLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMD---DVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKN-EDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSP-EFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQP------TKMSIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKILQVNTHQMIILLQFNH--HNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDE--FAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 777
[Close]
BLAST of Cullin vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 247.284 bits (630), Expect = 5.269e-70
Identity = 221/788 (28.05%), Postives = 384/788 (48.73%), Query Frame = 3 
Query:  126 AQLPKKINPFLELKTVKNEFET-NWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTD-YLVYVNTRLDEENERSQMYLS--GDSIRIQLRDQLVNIILKPHLDELL---KSGFNHMMENNDIFXXXXXXXX-XXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYF---PKG------------------------RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKG-QRVL---NKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
             Q   +I PF+   T+  ++ T  W +L++AI +I   +    + E LYR   +     + E ++N L+ +   H++    ++ +  ++   FL  +  SW ++ + + +IR I++++DR + + N+ ++  +++ +  +R   +    I   I    L+ I   R     +    K    M I L +     Y+  +E   L E   YY    +  L   ++   YL  V   + +E  R+  YL    ++  +Q+ D   ++++  H+  ++     G   M+E+  I  L  ++ +  ++ +S +    G+  L     EY+ ++G+ IV+N  D ++         L LK +  S++   F  D  F    +  FE FLN+    P E++A ++D  LRSG K +++  M+  +D VM LFR++  KDVFE ++ + LAKRLL+ KS   D EKA+L KLK ECG  +T+K+E MF D +    L+  F D    Q        K++I++++ V+    WP++  + ++ +PQ +      F+ +Y   H GRKL     LG   V+  F   PK                          K LQV+  Q ++LLQFN      ++   L   + I    LK+ L SL++GK  QR+L   NK   +  +SD+  F  N+NF  KLT++K   +  K   E E + T ++V  DR+  ++  IVR+MK+ + + H  LV +V ++LR     S   IK+RIE LIER+Y+ RD+ +   Y Y+A
Sbjct:    9 GQQKMRIRPFM--ATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGS-FLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMD---DVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKN-EDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSP-EFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQP------TKMSIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKILQVNTHQMIILLQFNH--HNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDE--FAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 777
[Close]
BLAST of Cullin vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 247.284 bits (630), Expect = 5.269e-70
Identity = 221/788 (28.05%), Postives = 384/788 (48.73%), Query Frame = 3 
Query:  126 AQLPKKINPFLELKTVKNEFET-NWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTD-YLVYVNTRLDEENERSQMYLS--GDSIRIQLRDQLVNIILKPHLDELL---KSGFNHMMENNDIFXXXXXXXX-XXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYF---PKG------------------------RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKG-QRVL---NKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
             Q   +I PF+   T+  ++ T  W +L++AI +I   +    + E LYR   +     + E ++N L+ +   H++    ++ +  ++   FL  +  SW ++ + + +IR I++++DR + + N+ ++  +++ +  +R   +    I   I    L+ I   R     +    K    M I L +     Y+  +E   L E   YY    +  L   ++   YL  V   + +E  R+  YL    ++  +Q+ D   ++++  H+  ++     G   M+E+  I  L  ++ +  ++ +S +    G+  L     EY+ ++G+ IV+N  D ++         L LK +  S++   F  D  F    +  FE FLN+    P E++A ++D  LRSG K +++  M+  +D VM LFR++  KDVFE ++ + LAKRLL+ KS   D EKA+L KLK ECG  +T+K+E MF D +    L+  F D    Q        K++I++++ V+    WP++  + ++ +PQ +      F+ +Y   H GRKL     LG   V+  F   PK                          K LQV+  Q ++LLQFN      ++   L   + I    LK+ L SL++GK  QR+L   NK   +  +SD+  F  N+NF  KLT++K   +  K   E E + T ++V  DR+  ++  IVR+MK+ + + H  LV +V ++LR     S   IK+RIE LIER+Y+ RD+ +   Y Y+A
Sbjct:    9 GQQKMRIRPFM--ATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGS-FLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMD---DVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKN-EDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSP-EFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQP------TKMSIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKILQVNTHQMIILLQFNH--HNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDE--FAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 777
[Close]
BLAST of Cullin vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 236.498 bits (602), Expect = 1.368e-66
Identity = 206/727 (28.34%), Postives = 355/727 (48.83%), Query Frame = 3 
Query:  309 IFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTD---YLVYVNTRLDEENERSQMYLS--GDSIRIQLRDQLVNIILKPHLDELL---KSGFNHMMENNDIFXXXXXXXX-XXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYF---PKG------------------------RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKG-QRVL---NKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ++N L+ +   H++    ++ +  ++   FL  +  SW ++ + + +IR I++++DR + + N+ ++  +++ +  +R   +    I   I    L+ I   R     +    K    M I L +     Y+  +E   L E   YY    +  L    + D   YL  V   + +E  R+  YL    ++  +Q+ D   ++++  H+  ++     G   M+E+  I  L  ++ +  ++ +S +    G+  L     EY+ ++G+ IV+N  D ++         L LK +  S++   F  D  F    +  FE FLN+    P E++A ++D  LRSG K +++  M+  +D VM LFR++  KDVFE ++ + LAKRLL+ KS   D EKA+L KLK ECG  +T+K+E MF D +    L+  F D    Q        K++I++++ V+    WP++  + ++ +PQ +      F+ +Y   H GRKL     LG   V+  F   PK                          K LQV+  Q ++LLQFN      ++   L   + I    LK+ L SL++GK  QR+L   NK   +  +SD+  F  N+NF  KLT++K   +  K   E E + T ++V  DR+  ++  IVR+MK+ + + H  LV +V ++LR     S   IK+RIE LIER+Y+ RD+ +   Y Y+A
Sbjct:   10 LYNGLKDVIQDHMASVRIRIIESMNSGS-FLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLS--GDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMD---DVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKN-EDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSP-EFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQP------TKMSIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKILQVNTHQMIILLQFNH--HNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDE--FAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 717
[Close]
BLAST of Cullin vs. Ensembl Fly
Match: Cul4 (gene:FBgn0033260 transcript:FBtr0301355)

HSP 1 Score: 473.396 bits (1217), Expect = 2.300e-154
Identity = 293/720 (40.69%), Postives = 446/720 (61.94%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYR-IVESFNPELNTEIFNNLRQLCLRHVSE-CAPKLYKDDSTDE-VFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ++ LE+A+  I  +  I+ +LE LY+ +V   + +++ +++  L++L  +HV      K     S D+ + L  I   W  +C ++ +IRSI L++DR +   NS++ S WDM + L+R  +    ++ K  V   L  I  +R G + D  L K++ +M  DL +Y   +E K+LD     Y  ES+RK++EL   +YL +VN RL EENER + YL   S +  L   +   +L  HL  +L+ G + ++E+N +  L LLY L   + + +++  G       F  ++ K G  IV +P    EKDK M Q+ LD K  +D +V  CF+ +  F  ++R+ FE F+N R NKPAE +AK++D KLRSGNK  T+E +E  +DK+M LFRFI GKDVFEAFY KDLAKRLL+GKSA VD+EK+ML KLK ECG  +T K+E MF D++ S+ ++  F   ++L N  ++D++  N+++ V+++    WP+   +++   PQ+ I+ Q  F+ FY   H+GRKL+++P+LG C++R  F  G KEL VS FQ +VLL FN   +  L+Y ++  A  I+   L++TL SL+ G+  RV+ K P   ++ D D F FN  F +KL +IK NQIQ KET EEQ+ATEE+VF DRQ  +D  IVR+MK  +++ H  L+T++  +L FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:  122 YVKLEEAVIAIQLSKPIKYSLEELYQAVVNMCSHKMDAQLYAKLKELTEQHVKRNIKLKELTGGSMDKLILLEKINHWWLSFCQQMIMIRSIFLYMDRTYVLQNSTVHSIWDMGLDLFRIHFAQNSVVQKRTVDGLLTLIEKERQGSTVDRGLLKSLVRMLCDLQIYTSSFEEKFLDATNQLYKAESQRKMQELEVPEYLQHVNKRLAEENERLRHYLDS-STKHPLIYNVEKELLAEHLTSILQKGLDSLLEDNRLSDLTLLYGLLSRVKNGTSELCG------NFNGFIKKKGRTIVIDP----EKDKSMVQDLLDFKDKMDVIVRTCFEHNEKFTNSLREAFEFFINQRANKPAELIAKYVDMKLRSGNKGTTDEELEKTLDKIMVLFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDSEKSMLSKLKQECGGGFTSKLEGMFKDMELSRDINIAFR-GHALSN--NRDVH--NLDLCVSILTMGYWPTYAPTEVTMPPQF-INPQQIFNKFYLEKHSGRKLQWQPTLGNCMLRAQFDAGPKELLVSLFQALVLLLFND--KPVLSYEEILAATLIEDGELRRTLQSLACGRA-RVITKTPKGREILDGDQFDFNNEFTNKLFRIKINQIQMKETNEEQKATEERVFQDRQYQIDAAIVRIMKMRKTLSHNLLITELFNQLTFPVKPADLKKRIESLIDRDYMERDKDNQNQYNYVA 821
[Close]
BLAST of Cullin vs. Ensembl Fly
Match: Cul4 (gene:FBgn0033260 transcript:FBtr0088821)

HSP 1 Score: 473.396 bits (1217), Expect = 2.300e-154
Identity = 293/720 (40.69%), Postives = 446/720 (61.94%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYR-IVESFNPELNTEIFNNLRQLCLRHVSE-CAPKLYKDDSTDE-VFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ++ LE+A+  I  +  I+ +LE LY+ +V   + +++ +++  L++L  +HV      K     S D+ + L  I   W  +C ++ +IRSI L++DR +   NS++ S WDM + L+R  +    ++ K  V   L  I  +R G + D  L K++ +M  DL +Y   +E K+LD     Y  ES+RK++EL   +YL +VN RL EENER + YL   S +  L   +   +L  HL  +L+ G + ++E+N +  L LLY L   + + +++  G       F  ++ K G  IV +P    EKDK M Q+ LD K  +D +V  CF+ +  F  ++R+ FE F+N R NKPAE +AK++D KLRSGNK  T+E +E  +DK+M LFRFI GKDVFEAFY KDLAKRLL+GKSA VD+EK+ML KLK ECG  +T K+E MF D++ S+ ++  F   ++L N  ++D++  N+++ V+++    WP+   +++   PQ+ I+ Q  F+ FY   H+GRKL+++P+LG C++R  F  G KEL VS FQ +VLL FN   +  L+Y ++  A  I+   L++TL SL+ G+  RV+ K P   ++ D D F FN  F +KL +IK NQIQ KET EEQ+ATEE+VF DRQ  +D  IVR+MK  +++ H  L+T++  +L FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:  122 YVKLEEAVIAIQLSKPIKYSLEELYQAVVNMCSHKMDAQLYAKLKELTEQHVKRNIKLKELTGGSMDKLILLEKINHWWLSFCQQMIMIRSIFLYMDRTYVLQNSTVHSIWDMGLDLFRIHFAQNSVVQKRTVDGLLTLIEKERQGSTVDRGLLKSLVRMLCDLQIYTSSFEEKFLDATNQLYKAESQRKMQELEVPEYLQHVNKRLAEENERLRHYLDS-STKHPLIYNVEKELLAEHLTSILQKGLDSLLEDNRLSDLTLLYGLLSRVKNGTSELCG------NFNGFIKKKGRTIVIDP----EKDKSMVQDLLDFKDKMDVIVRTCFEHNEKFTNSLREAFEFFINQRANKPAELIAKYVDMKLRSGNKGTTDEELEKTLDKIMVLFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDSEKSMLSKLKQECGGGFTSKLEGMFKDMELSRDINIAFR-GHALSN--NRDVH--NLDLCVSILTMGYWPTYAPTEVTMPPQF-INPQQIFNKFYLEKHSGRKLQWQPTLGNCMLRAQFDAGPKELLVSLFQALVLLLFND--KPVLSYEEILAATLIEDGELRRTLQSLACGRA-RVITKTPKGREILDGDQFDFNNEFTNKLFRIKINQIQMKETNEEQKATEERVFQDRQYQIDAAIVRIMKMRKTLSHNLLITELFNQLTFPVKPADLKKRIESLIDRDYMERDKDNQNQYNYVA 821
[Close]
BLAST of Cullin vs. Ensembl Fly
Match: Cul3 (gene:FBgn0261268 transcript:FBtr0302158)

HSP 1 Score: 279.641 bits (714), Expect = 1.222e-81
Identity = 230/779 (29.53%), Postives = 376/779 (48.27%), Query Frame = 3 
Query:  186 ETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELN---TEIFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDS----IRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKE------------YVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKE---------------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVL--NKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ET W  L+ AI +I   +    + E LYR   ++N  L+     ++  LR++   H+     K+  D  ++    FL  +  +W ++   + +IR I++++DR  +     + + +++ + L+RD  +    I K +    L  +  +R G + +    K    M I L +     Y+  +E  +L ++ ++Y  ES+  L E +   Y+  V  R+ EE+ R+ +YL  D+    +R+ + ++L+   ++P + E+  SG  +M++N                 SK+ D +  Y L +  KE            Y+ + G ++V+   +         QN LDLK   D  +   F  D  F   I   FE FLN   NK  EYL+ F+D KL+ G K ++E+ +E I+DK M LFRF+  KDVFE +Y   LAKRLL+ KS   D EK M+ KLK ECG  +T K+E MF D+  S  +  +F +      + + +++   +E+ V ++    WP+   +   NIP    +  + F  FY   H+GR+L  +P +GT  +   F  GRK                            LQVS +Q  VLL FN      LTY D+ +   I    L + L SLS+GK  QR+L  N +  +  +   D F  N+ F+ K  ++K   +  K   E E++ T  +V  DR+  ++  IVR+MK+ + + H  LV+DV  +L  RF      IKKRIE LIER+Y+ R   +  +Y+Y+A
Sbjct:   29 ETIWASLKNAIQEIQKKNNSGLSFEQLYR--NAYNMVLHKHGNRLYYGLREVVSEHLEH---KVRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDR-VYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRV-VEEELIKKHMRP-IVEMENSGVVYMIKN-----------------SKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLN-NKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNF-----VNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPREAFDIFKNFYLNKHSGRQLTLQPQMGTAYINAVF-YGRKAVESEKDKDAPSSSSSGCGVPTTTRKHILQVSTYQMCVLLLFNN--RDVLTYDDIHQETDIPERELVRALQSLSMGKPAQRLLVRNSKTKTKDIEPTDEFYVNDAFNSKFHRVKIQTVAAKGESEPERKETRGKVDEDRKHEIEAAIVRIMKARKRLAHNLLVSDVTSQLKSRFLPSPVFIKKRIEGLIEREYLQRSPEDRKVYNYLA 773
[Close]
BLAST of Cullin vs. Ensembl Fly
Match: Cul3 (gene:FBgn0261268 transcript:FBtr0302157)

HSP 1 Score: 279.641 bits (714), Expect = 1.222e-81
Identity = 230/779 (29.53%), Postives = 376/779 (48.27%), Query Frame = 3 
Query:  186 ETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELN---TEIFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDS----IRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKE------------YVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKE---------------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVL--NKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ET W  L+ AI +I   +    + E LYR   ++N  L+     ++  LR++   H+     K+  D  ++    FL  +  +W ++   + +IR I++++DR  +     + + +++ + L+RD  +    I K +    L  +  +R G + +    K    M I L +     Y+  +E  +L ++ ++Y  ES+  L E +   Y+  V  R+ EE+ R+ +YL  D+    +R+ + ++L+   ++P + E+  SG  +M++N                 SK+ D +  Y L +  KE            Y+ + G ++V+   +         QN LDLK   D  +   F  D  F   I   FE FLN   NK  EYL+ F+D KL+ G K ++E+ +E I+DK M LFRF+  KDVFE +Y   LAKRLL+ KS   D EK M+ KLK ECG  +T K+E MF D+  S  +  +F +      + + +++   +E+ V ++    WP+   +   NIP    +  + F  FY   H+GR+L  +P +GT  +   F  GRK                            LQVS +Q  VLL FN      LTY D+ +   I    L + L SLS+GK  QR+L  N +  +  +   D F  N+ F+ K  ++K   +  K   E E++ T  +V  DR+  ++  IVR+MK+ + + H  LV+DV  +L  RF      IKKRIE LIER+Y+ R   +  +Y+Y+A
Sbjct:   29 ETIWASLKNAIQEIQKKNNSGLSFEQLYR--NAYNMVLHKHGNRLYYGLREVVSEHLEH---KVRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDR-VYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRV-VEEELIKKHMRP-IVEMENSGVVYMIKN-----------------SKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLN-NKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNF-----VNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPREAFDIFKNFYLNKHSGRQLTLQPQMGTAYINAVF-YGRKAVESEKDKDAPSSSSSGCGVPTTTRKHILQVSTYQMCVLLLFNN--RDVLTYDDIHQETDIPERELVRALQSLSMGKPAQRLLVRNSKTKTKDIEPTDEFYVNDAFNSKFHRVKIQTVAAKGESEPERKETRGKVDEDRKHEIEAAIVRIMKARKRLAHNLLVSDVTSQLKSRFLPSPVFIKKRIEGLIEREYLQRSPEDRKVYNYLA 773
[Close]
BLAST of Cullin vs. Ensembl Fly
Match: Cul3 (gene:FBgn0261268 transcript:FBtr0302156)

HSP 1 Score: 279.641 bits (714), Expect = 1.222e-81
Identity = 230/779 (29.53%), Postives = 376/779 (48.27%), Query Frame = 3 
Query:  186 ETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELN---TEIFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDS----IRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKE------------YVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKE---------------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVL--NKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ET W  L+ AI +I   +    + E LYR   ++N  L+     ++  LR++   H+     K+  D  ++    FL  +  +W ++   + +IR I++++DR  +     + + +++ + L+RD  +    I K +    L  +  +R G + +    K    M I L +     Y+  +E  +L ++ ++Y  ES+  L E +   Y+  V  R+ EE+ R+ +YL  D+    +R+ + ++L+   ++P + E+  SG  +M++N                 SK+ D +  Y L +  KE            Y+ + G ++V+   +         QN LDLK   D  +   F  D  F   I   FE FLN   NK  EYL+ F+D KL+ G K ++E+ +E I+DK M LFRF+  KDVFE +Y   LAKRLL+ KS   D EK M+ KLK ECG  +T K+E MF D+  S  +  +F +      + + +++   +E+ V ++    WP+   +   NIP    +  + F  FY   H+GR+L  +P +GT  +   F  GRK                            LQVS +Q  VLL FN      LTY D+ +   I    L + L SLS+GK  QR+L  N +  +  +   D F  N+ F+ K  ++K   +  K   E E++ T  +V  DR+  ++  IVR+MK+ + + H  LV+DV  +L  RF      IKKRIE LIER+Y+ R   +  +Y+Y+A
Sbjct:   29 ETIWASLKNAIQEIQKKNNSGLSFEQLYR--NAYNMVLHKHGNRLYYGLREVVSEHLEH---KVRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDR-VYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRV-VEEELIKKHMRP-IVEMENSGVVYMIKN-----------------SKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLN-NKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNF-----VNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPREAFDIFKNFYLNKHSGRQLTLQPQMGTAYINAVF-YGRKAVESEKDKDAPSSSSSGCGVPTTTRKHILQVSTYQMCVLLLFNN--RDVLTYDDIHQETDIPERELVRALQSLSMGKPAQRLLVRNSKTKTKDIEPTDEFYVNDAFNSKFHRVKIQTVAAKGESEPERKETRGKVDEDRKHEIEAAIVRIMKARKRLAHNLLVSDVTSQLKSRFLPSPVFIKKRIEGLIEREYLQRSPEDRKVYNYLA 773
[Close]
BLAST of Cullin vs. Ensembl Zebrafish
Match: cul4b (cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208])

HSP 1 Score: 495.738 bits (1275), Expect = 2.357e-162
Identity = 307/721 (42.58%), Postives = 449/721 (62.27%), Query Frame = 3 
Query:  192 NWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPL--INKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
             W  L++A+  I N++ I+ NLE LY+ VE+  + +++ +++  LR +C  H+     + +++D+ D V FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R  YI   L   +K I   L  I  +R G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL  +L+ G N++++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QNI        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   D++ A GI+   L++TL SL+ GK  RVL K P S  V D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:  167 TWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISAKLYKQLRVVCEDHIKAQIDQ-FREDALDSVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFR-FYIISDLKVQSKTIDGILLLIERERSGEAVDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDVCFMKNEKFVNGMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQFKQHMQCQNIPG------NIELTVNILTMGYWPTYVPME-VHLPAEMVRLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EDIKLATGIEDSELRRTLQSLACGKA-RVLTKIPKSKDVEDGDKFSCNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYVA 864
[Close]
BLAST of Cullin vs. Ensembl Zebrafish
Match: cul4b (cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208])

HSP 1 Score: 458.759 bits (1179), Expect = 2.994e-148
Identity = 290/692 (41.91%), Postives = 425/692 (61.42%), Query Frame = 3 
Query:  192 NWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPL--INKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGS 2255
             W  L++A+  I N++ I+ NLE LY+ VE+  + +++ +++  LR +C  H+     + +++D+ D V FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R  YI   L   +K I   L  I  +R G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL  +L+ G N++++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QNI        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   D++ A GI+   L++TL SL+ GK  RVL K P S  V D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K S
Sbjct:  167 TWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISAKLYKQLRVVCEDHIKAQIDQ-FREDALDSVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFR-FYIISDLKVQSKTIDGILLLIERERSGEAVDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDVCFMKNEKFVNGMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQFKQHMQCQNIPG------NIELTVNILTMGYWPTYVPME-VHLPAEMVRLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EDIKLATGIEDSELRRTLQSLACGKA-RVLTKIPKSKDVEDGDKFSCNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKVS 835
[Close]
BLAST of Cullin vs. Ensembl Zebrafish
Match: cul4a (cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357])

HSP 1 Score: 412.535 bits (1059), Expect = 4.330e-133
Identity = 242/613 (39.48%), Postives = 364/613 (59.38%), Query Frame = 3 
Query:  186 ETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVL-CLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSD 2015
            E  WL L  A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  HV +     ++++S D + FL  +   W ++C +  +IRSI LF+DR +   NS L S WD  ++L+R   ++   +    V   L+Q+  +R G + D SL +++  M  DL +Y+  +E ++L E    Y+ E +R ++E    +YL +V  RL+EEN+R   YL   S +  L   +   +L  H+  +L+ G   +++ N +  L LLY L       S    G+  L   ++EY+   G   V +P    E+D++M Q  LD K  +DSV + CF+ + SF   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  TEE +E I+DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF     +QN  +      NIE+ VN++    WPS      +++P  M+ +Q  F  FY   H+GRKL+++P+LG  +++  F +G+KELQVS FQ +VLL FN   E   +  ++  A GI+   LK+TL SL+ GK  RVLNK P   +V D
Sbjct:   45 EDTWLKLRDAVSAIQNSTSIQYNLEELYQAVENLCSYKVSPMLYKQLRQVCEEHV-QAQIHQFREESLDSLSFLKRMNRCWQDHCRQTIMIRSIFLFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDAAVQSRTVQGILEQVERERSGETVDRSLLRSLLGMLSDLQVYKDSFEQRFLSETTRLYAAEGQRLMQERDVPEYLHHVARRLEEENDRVISYLD-QSTQKPLIATVEKQLLGEHMTTILQKGLRTLLDENRVCELTLLYELF------SKVKGGLTALLQSWREYIKSVGAETVCSP----ERDREMVQELLDFKDQMDSVTQSCFQRNESFINAMKEAFENFINQRPNKPAELIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF--KQYMQNQTEPS----NIELTVNILTMGYWPSYTPMD-VHLPAEMVKLQEVFKLFYLGKHSGRKLQWQPTLGHAVLKTEFKEGKKELQVSLFQTLVLLMFNESDE--CSVEEIRVATGIEEGELKRTLQSLACGKA-RVLNKTPRGKEVED 635
[Close]
BLAST of Cullin vs. Ensembl Zebrafish
Match: cul3b (cullin 3b [Source:ZFIN;Acc:ZDB-GENE-081007-1])

HSP 1 Score: 272.707 bits (696), Expect = 4.262e-79
Identity = 228/760 (30.00%), Postives = 377/760 (49.61%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYL---SGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIV------ENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTC-----------------IVRGYFPKG---RKE-LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX--XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W +L+ AI +I   +    + E LYR   +     + E ++  LR++   H+     K+ +D  +S +  FL  +  +WN++   + +IR I++++DR +   N+ + + +++ + ++RD  +    I   +    L  I  +R G   D    +   QM + L L     Y+  +E  +L+ +  ++  ES++ L E S + Y+  V  R++EE ER    L   + + I   +  +L++  +K  + E+  SG  HM++N     L  +Y L       S   +G+  +      Y+ + G  +V      +NP D +       Q  LDLK   D  +++ F  D  F +TI   FE FLN     P EYL+ F+D KL+ G K LTE+ +E I+DK M LFRF+  KDVFE +Y + LA+RLL  KS   D+EK M+ KLK ECG  +T K+E MF D+  S     +F      Q++    ++   +++ V V+    WP+   +   NIP         F  FY   H+GR+L  +  +G+                  +V G    G   RK  LQVS FQ  +L+ FN   +   T+ ++++   I    L + L SL+ GK  QRVL K P S ++ +  +F  N+ F  +L ++K   +  K+ +   E++ T ++V  DR+  ++  IVR+MKS + ++H  LV +V ++LR     S   IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:   33 WDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHL---INKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVIHCLDKSTEEPIVKVVERELISKHMKT-IVEMENSGLVHMLKNGKTEDLACMYKLF------SRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYI-------QGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFR-----QHLTSTGVSLGGVDLIVRVLTTGYWPTQSATPKCNIPPSPRHAFEVFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPIKKEDGSDMVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKS--TFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHVFTVNDQFTSRLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 766
[Close]
BLAST of Cullin vs. Ensembl Zebrafish
Match: cul3a (cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376])

HSP 1 Score: 271.937 bits (694), Expect = 9.252e-79
Identity = 226/757 (29.85%), Postives = 369/757 (48.75%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYL---SGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDI--FXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYF--PKGRKE--------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX--XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W +L+ AI +I   +    + E LYR   +     + E ++  LR++   H+     K+ +D   S +  FL  +  +WN++   + +IR I++++DR +   N+ + + +++ + ++RD  +    I   +    L  I  +R G   D    +   QM + L L     Y+  +E  +LD +  ++  ES++ L E S + Y+  V  R++EE ER    L   + + I   +  +L++  +K  + E+  SG  HM++N                    K+      + LR   K  V + G    +NP D +       Q  LDLK   D  +++ F  D  F +TI   FE FLN     P EYL+ F+D KL+ G K LTE+ +E I+DK M LFRF+  KDVFE +Y + LA+RLL  KS   D+EK M+ KLK ECG  +T K+E MF D+  S     +F       ++    ++   +++ V V+    WP+   +   NIP         F  FY   H+GR+L  +  +G+  +   F  P  +++                    LQVS FQ  +L+ FN   E F T+ ++++   I    L + L SL+ GK  QRVL K P S ++    +F  N+ F  KL ++K   +  K+ +   E++ T ++V  DR+  ++  IVR+MKS + ++H  LV +V ++LR     S   IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:   40 WDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHL---INKVREDVLHSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERRGEVVDRGAIRNACQMLMVLGLEGRSVYEEDFEIPFLDMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKT-IVEMENSGLVHMLKNGKTEDLACMYKLFGRVPNGLKTMCECMSWYLREQGKALVSEEGE--GKNPVDYI-------QGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFR-----HHLQTSQVSLCGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPIKKEDGSDVGVGGALLTGSNTRKHILQVSTFQMTILMLFNNR-EKF-TFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHVFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 774
[Close]
BLAST of Cullin vs. Ensembl Xenopus
Match: dnlz (DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-940250])

HSP 1 Score: 498.434 bits (1282), Expect = 2.526e-163
Identity = 306/729 (41.98%), Postives = 453/729 (62.14%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L+ A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++D+ D V FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R+  I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL   L+ G NH+++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D V++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++ +A GI+   L++TL SL+ G+  RVL K P S  V D D F FN++F H+L +I+ NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:  141 KLPENYTDETWQKLKGAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI-KAQIHQFREDALDSVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLNHLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHVIDVCFLKNEKFVNAMKEAFETFINKRPNKPAELIAKYVDSKLRTGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGQCVLKAEFNEGKKELQVSLFQTLVLLMFNEGDEFSL--EEIRQATGIEDSELRRTLQSLACGRA-RVLVKSPKSKDVDDGDKFTFNDDFRHQLFRIRINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYVA 847
[Close]
BLAST of Cullin vs. Ensembl Xenopus
Match: dnlz (DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-940250])

HSP 1 Score: 491.886 bits (1265), Expect = 2.042e-162
Identity = 304/728 (41.76%), Postives = 447/728 (61.40%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L+ A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+        K      +FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R+  I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL   L+ G NH+++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D V++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++ +A GI+   L++TL SL+ G+  RVL K P S  V D D F FN++F H+L +I+ NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:   29 KLPENYTDETWQKLKGAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI--------KAQIHHVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLNHLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHVIDVCFLKNEKFVNAMKEAFETFINKRPNKPAELIAKYVDSKLRTGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGQCVLKAEFNEGKKELQVSLFQTLVLLMFNEGDEFSL--EEIRQATGIEDSELRRTLQSLACGRA-RVLVKSPKSKDVDDGDKFTFNDDFRHQLFRIRINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYVA 727
[Close]
BLAST of Cullin vs. Ensembl Xenopus
Match: dnlz (DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-940250])

HSP 1 Score: 491.5 bits (1264), Expect = 5.721e-162
Identity = 304/728 (41.76%), Postives = 447/728 (61.40%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L+ A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+        K      +FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R+  I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL   L+ G NH+++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D V++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++ +A GI+   L++TL SL+ G+  RVL K P S  V D D F FN++F H+L +I+ NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:   45 KLPENYTDETWQKLKGAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI--------KAQIHHVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLNHLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHVIDVCFLKNEKFVNAMKEAFETFINKRPNKPAELIAKYVDSKLRTGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGQCVLKAEFNEGKKELQVSLFQTLVLLMFNEGDEFSL--EEIRQATGIEDSELRRTLQSLACGRA-RVLVKSPKSKDVDDGDKFTFNDDFRHQLFRIRINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYVA 743
[Close]
BLAST of Cullin vs. Ensembl Xenopus
Match: dnlz (DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-940250])

HSP 1 Score: 492.271 bits (1266), Expect = 6.035e-162
Identity = 304/728 (41.76%), Postives = 447/728 (61.40%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L+ A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+        K      +FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R+  I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL   L+ G NH+++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D V++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++ +A GI+   L++TL SL+ G+  RVL K P S  V D D F FN++F H+L +I+ NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:   73 KLPENYTDETWQKLKGAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI--------KAQIHHVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLNHLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHVIDVCFLKNEKFVNAMKEAFETFINKRPNKPAELIAKYVDSKLRTGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGQCVLKAEFNEGKKELQVSLFQTLVLLMFNEGDEFSL--EEIRQATGIEDSELRRTLQSLACGRA-RVLVKSPKSKDVDDGDKFTFNDDFRHQLFRIRINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYVA 771
[Close]
BLAST of Cullin vs. Ensembl Xenopus
Match: dnlz (DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-940250])

HSP 1 Score: 491.886 bits (1265), Expect = 3.672e-161
Identity = 304/728 (41.76%), Postives = 447/728 (61.40%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L+ A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+        K      +FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R+  I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL   L+ G NH+++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D V++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++ +A GI+   L++TL SL+ G+  RVL K P S  V D D F FN++F H+L +I+ NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:  122 KLPENYTDETWQKLKGAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI--------KAQIHHVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLNHLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHVIDVCFLKNEKFVNAMKEAFETFINKRPNKPAELIAKYVDSKLRTGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGQCVLKAEFNEGKKELQVSLFQTLVLLMFNEGDEFSL--EEIRQATGIEDSELRRTLQSLACGRA-RVLVKSPKSKDVDDGDKFTFNDDFRHQLFRIRINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYVA 820
[Close]
BLAST of Cullin vs. Ensembl Mouse
Match: Cul4b (cullin 4B [Source:MGI Symbol;Acc:MGI:1919834])

HSP 1 Score: 490.345 bits (1261), Expect = 8.221e-160
Identity = 303/729 (41.56%), Postives = 448/729 (61.45%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   +  K I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N +++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ MVLL FN   E  L   +++ A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  190 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQTKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQQFLQETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIASVEKQLLGEHLTAILQKGLNSLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDTCFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTMVLLMFNEGEEFSL--EEIKHATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 896
[Close]
BLAST of Cullin vs. Ensembl Mouse
Match: Cul4b (cullin 4B [Source:MGI Symbol;Acc:MGI:1919834])

HSP 1 Score: 489.574 bits (1259), Expect = 1.016e-158
Identity = 303/729 (41.56%), Postives = 448/729 (61.45%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   +  K I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N +++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ MVLL FN   E  L   +++ A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  264 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQTKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQQFLQETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIASVEKQLLGEHLTAILQKGLNSLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDTCFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTMVLLMFNEGEEFSL--EEIKHATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 970
[Close]
BLAST of Cullin vs. Ensembl Mouse
Match: Cul4b (cullin 4B [Source:MGI Symbol;Acc:MGI:1919834])

HSP 1 Score: 489.574 bits (1259), Expect = 1.016e-158
Identity = 303/729 (41.56%), Postives = 448/729 (61.45%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   +  K I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N +++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ MVLL FN   E  L   +++ A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  264 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQTKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQQFLQETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIASVEKQLLGEHLTAILQKGLNSLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDTCFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTMVLLMFNEGEEFSL--EEIKHATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 970
[Close]
BLAST of Cullin vs. Ensembl Mouse
Match: Cul4a (cullin 4A [Source:MGI Symbol;Acc:MGI:1914487])

HSP 1 Score: 480.715 bits (1236), Expect = 9.335e-158
Identity = 302/729 (41.43%), Postives = 448/729 (61.45%), Query Frame = 3 
Query:  177 NEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHV-SECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFN---GLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            N  +  W  L +A+  I +++ I  NLE LY+ VE+  + +++  ++  LRQ+C  HV ++  P  +++DS D V FL  I T W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R+  I+  ++ +K I   L  I  +R G + D SL +++  M  DL +Y+  +E K+L+E    Y+ E +R +++    +YL +V+ RL+EE +R   YL   S +  L   +   +L  HL  +L+ G  H+++ N +  L  +Y L       S    G + L  ++ EY+   GT IV NP    EKDK M Q+ LD K  +D VVE CF+ +  F   +++ FE F+N RPNKPAE +AK +DSKLR+GNK  T+E +E I+DK+M LFRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F     +QN          I++ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG  +++  F +G+KE QVS FQ +VLL FN   G      ++ +++ A GI+   L++TL SL+ GK  RVL K P   +V D D F FN +F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV+++  +L+FP+K  D+KKRIE LI+RDY+ RD+ + + YHYVA
Sbjct:   57 NYTQDTWRKLHEAVKAIQSSTSIRYNLEELYQAVENLCSHKVSPTLYKQLRQVCEDHVQAQILP--FREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDRMVQSKTIDGILLLIGRERSGEAVDRSLLRSLLSMLSDLQVYKDSFELKFLEETNCLYAAEGQRLMQDREVPEYLNHVSKRLEEEADRVITYLD-HSTQKPLIACVEKQLLGEHLTAILQKGLEHLLDENRVPDLTQMYQLF------SRVKGGQHALLQHWSEYIKTFGTTIVINP----EKDKDMVQDLLDFKDKVDHVVEVCFQRNERFINLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERILDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF--KQHMQN----QSAPGPIDLTVNILTMGYWPTYTPME-VHLPPEMVRLQEVFKTFYLGKHSGRKLQWQTTLGHAVLKADFKEGKKEFQVSLFQTLVLLMFNEGDG-----FSFEEIKMATGIEDSELRRTLQSLACGKA-RVLIKSPKGKEVEDGDKFIFNADFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDSPNQYHYVA 759
[Close]
BLAST of Cullin vs. Ensembl Mouse
Match: Cul3 (cullin 3 [Source:MGI Symbol;Acc:MGI:1347360])

HSP 1 Score: 273.478 bits (698), Expect = 2.478e-79
Identity = 226/758 (29.82%), Postives = 375/758 (49.47%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYL---SGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENN---DIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYF--PKGRKE--------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX--XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W +L+ AI +I   +    + E LYR   +     + E ++  LR++   H+     K+ +D  +S +  FL  +  +WN++   + +IR I++++DR +   N+ + + +++ + ++RD  +    I   +    L  I  +R G   D    +   QM + L L     Y+  +E  +L+ +  ++  ES++ L E S + Y+  V  R++EE ER    L   + + I   +  +L++  +K  + E+  SG  HM++N    D+  +  L++          +    Y LR   K  V + G    +NP D +       Q  LDLK   D  +++ F  D  F +TI   FE FLN     P EYL+ F+D KL+ G K LTE+ +E I+DK M LFRF+  KDVFE +Y + LA+RLL  KS   D+EK M+ KLK ECG  +T K+E MF D+  S     +F      Q++    ++   +++ V V+    WP+   +   NIP         F  FY   H+GR+L  +  +G+  +   F  P  +++                    LQVS FQ  +L+ FN   +   T+ ++++   I    L + L SL+ GK  QRVL K P S ++    +F  N+ F  KL ++K   +  K+ +   E++ T ++V  DR+  ++  IVR+MKS + ++H  LV +V ++L  RF      IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:   34 WDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHL---INKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKT-IVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCY-LREQGKALVSEEGE--GKNPVDYI-------QGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFR-----QHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREK--YTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768
[Close]
BLAST of Cullin vs. UniProt/SwissProt
Match: sp|Q13619|CUL4A_HUMAN (Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3)

HSP 1 Score: 498.819 bits (1283), Expect = 5.412e-164
Identity = 304/729 (41.70%), Postives = 446/729 (61.18%), Query Frame = 3 
Query:  177 NEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHV-SECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFN---GLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            N  +  W  L +A+  + +++ I  NLE LY+ VE+  + +++  ++  LRQ C  HV ++  P  +++DS D V FL  I T W ++C ++ +IRSI LF+DR +   NS+L S WDM ++L+R   I+  ++ +K I   L  I  +R G + D SL +++  M  DL +Y+  +E K+L+E    Y+ E +R ++E    +YL +V+ RL+EE +R   YL   S +  L   +   +L  HL  +L+ G +H+++ N +  L  +Y L       S    G   L  ++ EY+   GT IV NP    EKDK M Q+ LD K  +D V+E CF+ +  F   +++ FE F+N RPNKPAE +AK +DSKLR+GNK  T+E +E  +DK+M LFRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F     +QN  D       I++ VN++    WP+    ++   P+ MI +Q  F AFY   H+GRKL+++ +LG  +++  F +G+KE QVS FQ +VLL FN   G      ++ +++ A GI+   L++TL SL+ GK  RVL K P   +V D D F FN  F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV+++  +L+FP+K  D+KKRIE LI+RDY+ RD+ N + YHYVA
Sbjct:   57 NYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILP--FREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLD-HSTQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLF------SRVRGGQQALLQHWSEYIKTFGTAIVINP----EKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF--KQHMQNQSDSG----PIDLTVNILTMGYWPTYTPMEVHLTPE-MIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDG-----FSFEEIKMATGIEDSELRRTLQSLACGKA-RVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA 759
[Close]
BLAST of Cullin vs. UniProt/SwissProt
Match: sp|Q13620|CUL4B_HUMAN (Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4)

HSP 1 Score: 491.886 bits (1265), Expect = 2.101e-159
Identity = 303/729 (41.56%), Postives = 452/729 (62.00%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   + NK I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N++++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   ++++A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  207 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EEIKQATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913
[Close]
BLAST of Cullin vs. UniProt/SwissProt
Match: sp|A2A432|CUL4B_MOUSE (Cullin-4B OS=Mus musculus OX=10090 GN=Cul4b PE=1 SV=1)

HSP 1 Score: 489.574 bits (1259), Expect = 7.110e-158
Identity = 303/729 (41.56%), Postives = 448/729 (61.45%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+  + +++  ++  LRQ+C  H+ +     +++DS D V FL  I   W  +C ++ +IRSI LF+DR +   NS L S WDM ++L+R   I+   +  K I   L  I  +R+G + D SL +++  M  DL +YQ  +E ++L E    Y+ E ++ ++E    +YL +VN RL+EE +R   YL   + +  L   +   +L  HL  +L+ G N +++ N I  L LLY L       S    G+ +L   + EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN+        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ MVLL FN   E  L   +++ A GI+   L++TL SL+ GK  RVL K P    + D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+Y+A
Sbjct:  264 KLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISANLYKQLRQICEDHI-KAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQTKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQQFLQETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLD-QTTQKSLIASVEKQLLGEHLTAILQKGLNSLLDENRIQDLSLLYQLF------SRVRGGVQVLLQQWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIIDTCFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTMVLLMFNEGEEFSL--EEIKHATGIEDGELRRTLQSLACGKA-RVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 970
[Close]
BLAST of Cullin vs. UniProt/SwissProt
Match: sp|Q3TCH7|CUL4A_MOUSE (Cullin-4A OS=Mus musculus OX=10090 GN=Cul4a PE=1 SV=1)

HSP 1 Score: 480.715 bits (1236), Expect = 6.530e-157
Identity = 302/729 (41.43%), Postives = 448/729 (61.45%), Query Frame = 3 
Query:  177 NEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHV-SECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFN---GLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            N  +  W  L +A+  I +++ I  NLE LY+ VE+  + +++  ++  LRQ+C  HV ++  P  +++DS D V FL  I T W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R+  I+  ++ +K I   L  I  +R G + D SL +++  M  DL +Y+  +E K+L+E    Y+ E +R +++    +YL +V+ RL+EE +R   YL   S +  L   +   +L  HL  +L+ G  H+++ N +  L  +Y L       S    G + L  ++ EY+   GT IV NP    EKDK M Q+ LD K  +D VVE CF+ +  F   +++ FE F+N RPNKPAE +AK +DSKLR+GNK  T+E +E I+DK+M LFRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +   F     +QN          I++ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG  +++  F +G+KE QVS FQ +VLL FN   G      ++ +++ A GI+   L++TL SL+ GK  RVL K P   +V D D F FN +F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV+++  +L+FP+K  D+KKRIE LI+RDY+ RD+ + + YHYVA
Sbjct:   57 NYTQDTWRKLHEAVKAIQSSTSIRYNLEELYQAVENLCSHKVSPTLYKQLRQVCEDHVQAQILP--FREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDRMVQSKTIDGILLLIGRERSGEAVDRSLLRSLLSMLSDLQVYKDSFELKFLEETNCLYAAEGQRLMQDREVPEYLNHVSKRLEEEADRVITYLD-HSTQKPLIACVEKQLLGEHLTAILQKGLEHLLDENRVPDLTQMYQLF------SRVKGGQHALLQHWSEYIKTFGTTIVINP----EKDKDMVQDLLDFKDKVDHVVEVCFQRNERFINLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERILDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHF--KQHMQN----QSAPGPIDLTVNILTMGYWPTYTPME-VHLPPEMVRLQEVFKTFYLGKHSGRKLQWQTTLGHAVLKADFKEGKKEFQVSLFQTLVLLMFNEGDG-----FSFEEIKMATGIEDSELRRTLQSLACGKA-RVLIKSPKGKEVEDGDKFIFNADFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDSPNQYHYVA 759
[Close]
BLAST of Cullin vs. UniProt/SwissProt
Match: sp|Q8LGH4|CUL4_ARATH (Cullin-4 OS=Arabidopsis thaliana OX=3702 GN=CUL4 PE=1 SV=1)

HSP 1 Score: 448.743 bits (1153), Expect = 2.898e-144
Identity = 281/747 (37.62%), Postives = 434/747 (58.10%), Query Frame = 3 
Query:  126 AQLPKKINPF-LELKTVKNEFETN-----WLILEQAIHKIFNNSFIETNLESLYRIVESFN-PELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVL-CLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            A LP+    F ++L   K    TN     W  L+ AI  IF    I  +LESLY+ V++    +L+ ++++ + + C  H+S     L   ++   VFL+ +   W ++C ++ +IRSI L +DRK+   N ++ S W+M +QL+R      P + +  V   L  I  +R   + + +L   + +MF  L +Y   +E  +L+    +Y+ E  + +++    +YL +V  RL EENER  +Y+   + R  L   +   +L+ H+  +L+ GF  +M+              Q + +  +  + +  LR     YV K+G  IV     D EKDK M Q+ LD K  LD + E+ F  + SF  TI+D FE  +N R N+PAE +AKFLD KLR+GNK  +EE +E +++KV+ LFRFI GKDVFEAFY KDLAKRLL+GKSA +D EK+M+ KLK ECG  +T K+E MF DI+ S+ +++ F  S+  +  +        IEM+V+V+    WP+      + +P  +   Q+ F  FY   ++GR+L ++ SLG C+++  F KG+KEL VS FQ +VL+ FN    M L++ D++ +  I+   L++TL SL+ GK  RVL K P    V D D F FN+ F   L +IK N IQ KET EE  +T E+VF DRQ  +D  IVR+MK+ + + HT L+T++ ++L+FP+K +D+KKRIE LI+R+Y+ R++SN  +Y+Y+A
Sbjct:   67 ATLPQPTKKFVIKLNKAKPTLPTNFEENTWEKLQSAIRAIFLKKKISFDLESLYQAVDNLCLHKLDGKLYDQIEKECEEHISAALQSLVGQNTDLTVFLSRVEKCWQDFCDQMLMIRSIALTLDRKYVIQNPNVRSLWEMGLQLFRKHLSLAPEVEQRTVKGLLSMIEKERLAEAVNRTLLSHLLKMFTALGIYMESFEKPFLEGTSEFYAAEGMKYMQQSDVPEYLKHVEGRLHEENERCILYIDAVT-RKPLITTVERQLLERHILVVLEKGFTTLMDGR-------RTEDLQRMQTLFSRVNALESLRQALSSYVRKTGQKIVM----DEEKDKDMVQSLLDFKASLDIIWEESFYKNESFGNTIKDSFEHLINLRQNRPAELIAKFLDEKLRAGNKGTSEEELESVLEKVLVLFRFIQGKDVFEAFYKKDLAKRLLLGKSASIDAEKSMISKLKTECGSQFTNKLEGMFKDIELSKEINESFKQSSQARTKLPS-----GIEMSVHVLTTGYWPTYPPMD-VKLPHELNVYQDIFKEFYLSKYSGRRLMWQNSLGHCVLKADFSKGKKELAVSLFQAVVLMLFND--AMKLSFEDIKDSTSIEDKELRRTLQSLACGKV-RVLQKNPKGRDVEDGDEFEFNDEFAAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQIDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKPADLKKRIESLIDREYLEREKSNPQIYNYLA 792
[Close]
BLAST of Cullin vs. TrEMBL
Match: A0A4S2M5W0 (CULLIN_2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002466 PE=3 SV=1)

HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0
Identity = 329/731 (45.01%), Postives = 480/731 (65.66%), Query Frame = 3 
Query:  183 FETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPE-LNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNH------ITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCL-KQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKG---RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            FET W  L++A   +  +  +E  LE LYR VE    + +  E+++ L+ L   +V++  P          VFLN       +  SW  YC K+ +IR+I LF+DR+   +NS  +  WD+A+ L+R+  I+   +   I+  L  +I  +R G + + +L +++ +MF+DL LYQ  + P+++ +++ +Y+QES   L+ +S  DYLV+V+ R+ EE +R   YL  +S R  L   LV+ +L   LD LL++G    ++  +   L L Y+L       S   +G+  LR +F++YV++ G  +VENP  D EKD+ M QN +  + +L  ++  CF  D +F + +++ +E F+N RPNKPAE+LAK+LD+ LRSGNK  T+E ++ +MDK M LFR+I GKD+FEAFY K+LAKRLL+ KSA VD EK+ML KLK ECGPNYTRKME MF DI+ S++LSK F  S  L +         +IE+NVNVI  ++WP+   +   N P  M+ +++ F+ FY   H GRKL +EPSLGTC+V+  FP     RKELQVSEFQ +VLLQFNG     ++Y  + +A GI+   LK+TLLSL+ GKGQRVL K P++  V++D  F FN  F H+LT+IKFNQIQ +ETK+EQ+ATEE+VFADR AH+DCCIVR+MK+ ++I+H  L+++V K+L+FPLK SD+KKRIE+LIERDY+ RD ++++ YHYV+
Sbjct:   47 FETAWPKLKRATTAVLQSKPVEFTLEELYRNVEDICAQRMLLELYSTLKALLKDYVADLLP----------VFLNEAMQLGSVANSWEVYCKKMLLIRNIFLFMDRQLLISNSQYVQIWDLALNLFREEVISHDKVEGRILRQLFDEIRKERSGEAVNRNLLRSIIRMFVDLKLYQSTFLPEFIRQSQQFYTQESNAFLRLMSVPDYLVHVDKRIKEEEDRLVSYLEPNSTRKLLLSTLVSELLTRTLDHLLENGLVGSLKAKETKQLGLFYSLL------SKVPNGVDKLRTHFRQYVIQLGRDLVENPTQDPEKDRNMIQNLISCRDYLSELIATCFANDANFTRVLQEAYEEFINQRPNKPAEFLAKYLDAHLRSGNKAQTDEELDKLMDKAMMLFRYIDGKDIFEAFYTKELAKRLLLNKSASVDAEKSMLSKLKQECGPNYTRKMETMFQDIELSKQLSKNFRASYCLDH---------SIELNVNVISPSSWPAYPQTN-ANYPPEMMALRDEFTRFYLSHHQGRKLLYEPSLGTCVVKAEFPLTPHLRKELQVSEFQALVLLQFNGDPNESVSYATIAEATGIEETELKRTLLSLAAGKGQRVLIKHPTNLDVANDHTFKFNAEFQHRLTRIKFNQIQLRETKQEQEATEERVFADRVAHVDCCIVRIMKTRKTIDHNSLLSEVYKQLQFPLKASDVKKRIENLIERDYMKRDTTSAATYHYVS 751
[Close]
BLAST of Cullin vs. TrEMBL
Match: C7TYV2 (Cullin OS=Schistosoma japonicum OX=6182 GN=cul-4 PE=2 SV=1)

HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0
Identity = 334/741 (45.07%), Postives = 471/741 (63.56%), Query Frame = 3 
Query:  138 KKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPE-LNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLC--LKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKG---RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K I+    L +    FE + L L++A   +F +  +E+ LE LYR VE    + +  E++++L+ L    V+E  P+  K        L+ +   W  YC K+ +IR+I LF+DR+    +   +  WD+A++L+R+  IT   +   + LC  L +IH +R G + D  L + V +M +DL LY   + P++L +++  Y+ E++   + L+  +YL++V+ R+ EE +R  +YL  +S R  L   LV+ +L   LD LL +G    ++      L LL++L       S   +GI  LR +F+ Y+++ G  +VENP  D EKD+ M QN LD +  L  ++  CF  D SF + +++ +E F+N RPNKPAE+LAK+LDS LRSGNK  TEE ++ +MDK M LFRFI GKD+FEAFY K+LAKRLL+ KSA VD EKAML KLK ECGPNYTRKME MF DI+ S++LSK F  S              +IE++VNVIC A+WP    +   N P  M+ ++  F+ FY   H GRKL +EPSLGTC+V+  FP     RKELQVSE Q +VLLQFN      +TY  + +  GI+   LK+TLLSL+ GKGQRVL K P + ++ +D  F FN  F H+LT+IKFNQIQ KET++EQ ATEE+VFADR AH+DCCIVR+MK+ ++I+H  L+++V K L+FPLK SDIKKRIE+LIERDY+ RD SN++ YHYV+
Sbjct:   31 KAISDLKGLPSASQIFEDSCLKLQKATKAVFLSEPVESTLEELYRNVEDICAQRMVMELYSSLKILFSEFVAELQPQFLKVGFQ----LSAVAHCWGLYCKKMLLIRNIFLFMDRQLLILDPQNLQIWDLALKLFREDVITLEKVQSRL-LCQILDEIHKERCGEAIDRQLLRTVIRMLVDLKLYDSIFLPEFLRKSQQLYTYEADLLTRTLNVPEYLLHVDKRIIEEEDRLVVYLDANSTRGLLMSTLVSELLTRPLDHLLDNGLVTPLKTKQTSQLSLLFSLI------SRAPNGIDKLRTHFRNYIIQMGREMVENPTQDPEKDRAMIQNLLDSRDFLSEIIVSCFSNDSSFMRVLQEAYEEFINQRPNKPAEFLAKYLDSHLRSGNKAQTEEELDKLMDKAMILFRFIDGKDIFEAFYTKELAKRLLLNKSASVDAEKAMLSKLKQECGPNYTRKMETMFQDIELSRQLSKNFRLSLP---------GTHSIELSVNVICPASWPPYPQTT-ANYPPEMVALREEFTRFYLSHHQGRKLMYEPSLGTCVVKAKFPTTPNLRKELQVSELQALVLLQFNQSDNAPITYMTIAENTGIEEKELKRTLLSLAAGKGQRVLIKTPGNLEIENDHQFIFNAEFRHRLTRIKFNQIQLKETEQEQVATEERVFADRVAHVDCCIVRIMKTRKTIDHNSLLSEVYKHLQFPLKASDIKKRIENLIERDYMKRDSSNAAAYHYVS 750
[Close]
BLAST of Cullin vs. TrEMBL
Match: A0A4S2M5U7 (CULLIN_2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002466 PE=3 SV=1)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 330/756 (43.65%), Postives = 482/756 (63.76%), Query Frame = 3 
Query:  183 FETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPE-LNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNH------ITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCL-KQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMT-------------------------LFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKG---RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            FET W  L++A   +  +  +E  LE LYR VE    + +  E+++ L+ L   +V++  P          VFLN       +  SW  YC K+ +IR+I LF+DR+   +NS  +  WD+A+ L+R+  I+   +   I+  L  +I  +R G + + +L +++ +MF+DL LYQ  + P+++ +++ +Y+QES   L+ +S  DYLV+V+ R+ EE +R   YL  +S R  L   LV+ +L   LD LL++G    ++  +   L L Y+L       S   +G+  LR +F++YV++ G  +VENP  D EKD+ M QN +  + +L  ++  CF  D +F + +++ +E F+N RPNKPAE+LAK+LD+ LRSGNK  T+E ++ +MDKVM+                         LFR+I GKD+FEAFY K+LAKRLL+ KSA VD EK+ML KLK ECGPNYTRKME MF DI+ S++LSK F  S  L +         +IE+NVNVI  ++WP+   +   N P  M+ +++ F+ FY   H GRKL +EPSLGTC+V+  FP     RKELQVSEFQ +VLLQFNG     ++Y  + +A GI+   LK+TLLSL+ GKGQRVL K P++  V++D  F FN  F H+LT+IKFNQIQ +ETK+EQ+ATEE+VFADR AH+DCCIVR+MK+ ++I+H  L+++V K+L+FPLK SD+KKRIE+LIERDY+ RD ++++ YHYV+
Sbjct:   47 FETAWPKLKRATTAVLQSKPVEFTLEELYRNVEDICAQRMLLELYSTLKALLKDYVADLLP----------VFLNEAMQLGSVANSWEVYCKKMLLIRNIFLFMDRQLLISNSQYVQIWDLALNLFREEVISHDKVEGRILRQLFDEIRKERSGEAVNRNLLRSIIRMFVDLKLYQSTFLPEFIRQSQQFYTQESNAFLRLMSVPDYLVHVDKRIKEEEDRLVSYLEPNSTRKLLLSTLVSELLTRTLDHLLENGLVGSLKAKETKQLGLFYSLL------SKVPNGVDKLRTHFRQYVIQLGRDLVENPTQDPEKDRNMIQNLISCRDYLSELIATCFANDANFTRVLQEAYEEFINQRPNKPAEFLAKYLDAHLRSGNKAQTDEELDKLMDKVMSAVDVVARDHSGCSAWRCRLGESAMMLFRYIDGKDIFEAFYTKELAKRLLLNKSASVDAEKSMLSKLKQECGPNYTRKMETMFQDIELSKQLSKNFRASYCLDH---------SIELNVNVISPSSWPAYPQTN-ANYPPEMMALRDEFTRFYLSHHQGRKLLYEPSLGTCVVKAEFPLTPHLRKELQVSEFQALVLLQFNGDPNESVSYATIAEATGIEETELKRTLLSLAAGKGQRVLIKHPTNLDVANDHTFKFNAEFQHRLTRIKFNQIQLRETKQEQEATEERVFADRVAHVDCCIVRIMKTRKTIDHNSLLSEVYKQLQFPLKASDVKKRIENLIERDYMKRDTTSAATYHYVS 776
[Close]
BLAST of Cullin vs. TrEMBL
Match: C1LD65 (Cullin OS=Schistosoma japonicum OX=6182 GN=cul-4 PE=2 SV=1)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 334/741 (45.07%), Postives = 471/741 (63.56%), Query Frame = 3 
Query:  138 KKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPE-LNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLC--LKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKG---RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K I+    L +    FE + L L++A   +F +  +E+ LE LYR VE    + +  E++++L+ L    V+E  P+  K        L+ +   W  YC K+ +IR+I LF+DR+    +   +  WD+A++L+R+  IT   +   + LC  L +IH +R G + D  L + V +M +DL LY   + P++L +++  Y+ E++   + L+  +YL++V+ R+ EE +R  +YL  +S R  L   LV+ +L   LD LL +G    ++      L LL++L       S   +GI  LR +F+ Y+++ G  +VENP  D EKD+ M QN LD +  L  ++  CF  D SF + +++ +E F+N RPNKPAE+LAK+LDS LRSGNK  TEE ++ +MDK M LFRFI GKD+FEAFY K+LAKRLL+ KSA VD EKAML KLK ECGPNYTRKME MF DI+ S++LSK F  S              +IE++VNVIC A+WP    +   N P  M+ ++  F+ FY   H GRKL +EPSLGTC+V+  FP     RKELQVSE Q +VLLQFN      +TY  + +  GI+   LK+TLLSL+ GKGQRVL K P + ++ +D  F FN  F H+LT+IKFNQIQ KET++EQ ATEE+VFADR AH+DCCIVR+MK+ ++I+H  L+++V K L+FPLK SDIKKRIE+LIERDY+ RD SN++ YHYV+
Sbjct:   31 KAISDLKGLPSASQIFEDSCLKLQKATKAVFLSEPVESTLEELYRNVEDICAQRMVMELYSSLKILFSEFVAELQPQFLKVGFQ----LSAVAHCWGLYCKKMLLIRNIFLFMDRQLLILDPQNLQIWDLALKLFREDVITLEKVQSRL-LCQILDEIHKERCGEAIDRQLLRTVIRMLVDLKLYDSIFLPEFLRKSQQLYTYEADLLTRTLNVPEYLLHVDKRIIEEEDRLVVYLDANSTRGLLMSTLVSELLTRPLDHLLDNGLVTPLKTKQTSQLSLLFSLI------SRVPNGIDKLRTHFRNYIIQMGREMVENPTQDPEKDRAMIQNLLDSRDFLSEIIVSCFSNDSSFMRVLQEAYEEFINQRPNKPAEFLAKYLDSHLRSGNKAQTEEELDKLMDKAMILFRFIDGKDIFEAFYTKELAKRLLLNKSASVDAEKAMLSKLKQECGPNYTRKMETMFQDIELSRQLSKNFRLSLP---------GTHSIELSVNVICPASWPPYPQTT-ANYPPEMVALREEFTRFYLSHHQGRKLMYEPSLGTCVVKAKFPTTPNLRKELQVSELQALVLLQFNQSDNAPITYMTIAENTGIEEKELKRTLLSLAAGKGQRVLIKTPGNLEIENDHQFIFNAEFRHRLTRIKFNQIQLKETEQEQVATEERVFADRVAHVDCCIVRIMKTRKTIDHNSLLSEVYKHLQFPLKASDIKKRIENLIERDYMKRDSSNAATYHYVS 750
[Close]
BLAST of Cullin vs. TrEMBL
Match: G4VC72 (Putative cullin OS=Schistosoma mansoni OX=6183 GN=Smp_082850.2 PE=3 SV=1)

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 330/741 (44.53%), Postives = 473/741 (63.83%), Query Frame = 3 
Query:  138 KKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPE-LNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLC--LKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKG---RKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K I+    L +    F+ + L L++A   +F +  +E+ LE LYR VE    + +  E++++L+ +   +V+   P+  K        L+ +   W  YC K+ +IR+I LF+DR+    N   +  WD+A++L+R+  IT   +   + +C  L +IH +R G + D  L + V +M +DL LY   +  ++L +++  Y+ E++   ++LS  +YL++V+ R+ EE +R  +YL  +S R  L   LV+ +L   LD LL +G  + ++      L LL++L       S   +GI  LR +F+ Y+ + G  +VENP  D EKD+ M QN LD +  L  +   CF  D SF + +++ +E F+N RPNKPAE+LAK+LDS LRSGNK  TEE ++ +MDK M LFRFI GKD+FEAFY K+LAKRLL+ KSA VD EKAML KLK ECGPNYTRKME MF DI+ S++LSK F  S           +   IE++VNVIC A+WP    +   N P  M+ ++  F+ FY   H GRKL +EPSLGTC+V+  FP     RKELQVSE Q +VLLQFN      +TYT + +  GI+   LK+TLLSL+ GKGQRVL K P + ++ ++  F FN  FHH+LT+IKFNQ+Q KET++EQ ATEE+VFADR AH+DCCIVR+MK+ ++I+H  L+++V K+L+FPLK SD+KKRIE+LIERDY+ RD SN++ YHYV+
Sbjct:   31 KAISDVKGLPSASQIFQDSCLKLQKATKAVFLSEPVESTLEELYRNVEDICAQKMIMELYSSLKVIFSEYVAGLQPQFLKVGFQ----LSAVAQCWGLYCKKMLLIRNIFLFMDRQLLQLNPQNLQIWDLALKLFREDVITQEKVQSRL-MCQILDEIHKERCGEAIDRQLLRTVIRMLVDLKLYDSIFLAEFLCKSQQLYAYEADTLSRQLSVPEYLLHVDKRIIEEEDRLVVYLDANSTRSLLISTLVSELLTRPLDYLLDNGLVNPLKTKQTSQLSLLFSLV------SRVPNGIEKLRIHFRNYITQMGREMVENPTHDPEKDRNMIQNLLDSRDFLSEITVSCFSNDPSFMRVLQEAYEEFINQRPNKPAEFLAKYLDSHLRSGNKAQTEEELDKLMDKAMILFRFIDGKDIFEAFYTKELAKRLLLNKSASVDAEKAMLSKLKQECGPNYTRKMETMFQDIELSKQLSKNFRLSLP---------DTYAIELSVNVICPASWPPYPQTT-ANYPPEMVALREEFTRFYLSHHQGRKLIYEPSLGTCVVKAKFPTTPNLRKELQVSELQALVLLQFNQSDNAPITYTTIAENTGIEEKELKRTLLSLAAGKGQRVLKKTPGNLEIENNHQFIFNTEFHHRLTRIKFNQVQLKETEQEQVATEERVFADRVAHVDCCIVRIMKTRKTIDHNSLLSEVYKQLQFPLKASDVKKRIENLIERDYMKRDSSNAATYHYVS 750
[Close]
BLAST of Cullin vs. Ensembl Cavefish
Match: cul4a (cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357])

HSP 1 Score: 470.315 bits (1209), Expect = 9.342e-156
Identity = 274/633 (43.29%), Postives = 399/633 (63.03%), Query Frame = 3 
Query:  447 IIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVL-CLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            +IRSI LF+DR +   NS L S WD  ++L+R   ++  ++    V   L+QI  +R+G + D SL +++  M  DL +Y+  +E K+L +    Y+ E +R + E    +YL +V  RL+EEN+R   YL   S +  L   +   +L  H+  +L+ G + +++ N +  L LLY L       S    G+ +L  ++++Y+   G  IV +P    EKDK M Q  LD K  +D+V ++CF+ + SF   +++ FE+F+N RPNKPAE +AK++DSKLR+GNK  TEE +E I+DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF     +QN         NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++P+LG  +++  F +G+KELQVS FQ +VLL FN   E   T  +++ A GI+   LK+TL SL+ GK  RVLNK P    V D D F FN +F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  +VR+MK  +++ H  LV+++  +L+FP+K  D+KKRIE LI+RDY+ RD+ + + YHYVA
Sbjct:    1 MIRSIFLFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDNMVQSRTVQGILEQIERERNGETVDRSLLRSLLGMLSDLQVYKESFEQKFLVDTDRLYAAEGQRLMLERDVPEYLHHVARRLEEENDRVISYLD-QSTQKPLISTVEKQLLGEHMTAILQKGLSTLLDENRVTELTLLYQLF------SKVKGGLPVLLQFWRDYIKSFGGEIVGSP----EKDKDMVQELLDFKDKMDNVAQRCFQRNESFINAMKEAFESFINKRPNKPAELIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF--KQYMQN----QSEPSNIELTVNILTMGYWPTYTPME-VHLPAEMVKLQEVFKMFYLGKHSGRKLQWQPTLGHAVLKAEFKEGKKELQVSLFQTLVLLMFNEGEE--FTLEEIQTATGIEEGELKRTLQSLACGKA-RVLNKNPRGKDVEDGDRFNFNIDFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAVVRIMKMRKTLSHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKESPNQYHYVA 612
[Close]
BLAST of Cullin vs. Ensembl Cavefish
Match: cul4b (cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208])

HSP 1 Score: 467.618 bits (1202), Expect = 1.301e-151
Identity = 300/729 (41.15%), Postives = 440/729 (60.36%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPL--INKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N     W  L++A+  I N++ I+ NLE LY+ VE+  + +++ +++  LR +C  H+     + +++     +FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R  YI   L   +K I   L  I  +R G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE+  S   L  +   I   ++    +L  HL   L+ G NH+++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +DS+++ CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QNI        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +V L FN   E    +  L+         L++TL SL+ GK  RVL K P S  V D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K S + KRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:  157 KLPENYTHETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISPKLYKQLRAVCEDHIKAQIDQ-FREYPFHVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFR-FYIISDLKVQSKTIDGILLLIERERSGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEESRPSHHILGPEKPLIATVEKQ---LLGEHLTATLQKGLNHLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDSIIDVCFMKNEKFVNAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQFKQYMQCQNIPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVRLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVRLMFNEGEE--FPWKRLKDG------ELRRTLQSLACGKA-RVLTKIPKSKDVEDGDKFSCNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKVS-VHKRIESLIDRDYMERDKENPNQYNYVA 853
[Close]
BLAST of Cullin vs. Ensembl Cavefish
Match: ENSAMXT00000057183.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001049.1:257741:270576:1 gene:ENSAMXG00000034138.1 transcript:ENSAMXT00000057183.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 427.943 bits (1099), Expect = 3.687e-139
Identity = 276/640 (43.12%), Postives = 391/640 (61.09%), Query Frame = 3 
Query:  447 IIRSIMLFVDRKFWSNN-----SSLMSFWDMAMQLWRDMYITGPL--INKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYL-AKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            +IRSI     R +   N     S      DM ++L+R  YI   L   +K I   L  I  +R G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +VN RL+EE +R   YL   S +  L   +   +L  HL   L+ G NH+++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +DS+++ CF  +  F   +++ FE F+N RPNKPAE + +K++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QNI        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L   +++ A GI+   L++TL SL+ GK  RVL K P S  V D D F  N++F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  LV++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ N + Y+YVA
Sbjct:   18 MIRSIFFVFGRTYVLTNLCCHLSGTYLLLDMGLELFR-FYIISDLKVQSKTIDGILLLIERERSGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLNHLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDSIIDVCFMKNEKFVNAMKEAFETFINKRPNKPAELIGSKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQFKQYMQCQNIPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVRLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EEIKLATGIEDGELRRTLQSLACGKA-RVLTKIPKSKDVEDGDKFSCNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYVA 635
[Close]
BLAST of Cullin vs. Ensembl Cavefish
Match: cul3b (cullin 3 [Source:NCBI gene;Acc:103024283])

HSP 1 Score: 278.485 bits (711), Expect = 3.240e-81
Identity = 227/761 (29.83%), Postives = 375/761 (49.28%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYL---SGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIV------ENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKE----------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX--XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W +L+ AI +I   +    + E LYR   +     + E ++  LR++   H+     K+  D  +S +  FL  +  +WN++   + +IR I++++DR +   N+ + + +++ + ++RD  +    I   +    L  I  +R G   D    +   QM + L L     Y+  +E  +L+ +  ++  ES++ L E S + Y+  V  R++EE ER    L   + + I   +  +L++  +K  + E+  SG  HM++N     L  +Y L       S   +G+  +      Y+ + G  +V      +NP D +       Q  LDLK   D  +++ F  D  F +TI   FE FLN  P  P EYL+ F+D KL+ G K LTE+ +E I+DK M LFRF+  KDVFE +Y + LA+RLL  KS   D+EK M+ KLK ECG  +T K+E MF D+  S     +F      Q++    ++   +++ V V+    WP+   +   NIP         F  FY   H+GR+L  +  +G+  +   F    K+                      LQVS FQ  +L+ FN   +   T+ ++++   I    L + L SL+ GK  QRVL K P S ++ +  +F  N+ F  KL ++K   +  K+ +   E++ T ++V  DR+  ++  IVR+MKS + ++H  LV +V ++LR     S   IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:   33 WDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHL---INKVRDDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLQQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKT-IVEMENSGLVHMLKNGKTEDLACMYKLF------SRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYI-------QGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNPRSP-EYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFR-----QHLQSTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVFRRFYLAKHSGRQLTLQHHMGSADLNATFYGAIKKEDGSDIGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKS--TFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHVFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 767
[Close]
BLAST of Cullin vs. Ensembl Cavefish
Match: cul3a (cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376])

HSP 1 Score: 275.018 bits (702), Expect = 4.729e-79
Identity = 225/758 (29.68%), Postives = 375/758 (49.47%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKDD--STDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYL---SGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENN---DIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRG--YFPKGRKE--------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX--XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W +L+ AI +I   +    + E LYR   +     + E ++  LR++   H+     K+ +D   S +  FL  +  +WN++   + +IR I++++DR +   N+ + + +++ + ++RD  +    I   +    L  I  +R G   D    +   QM + L L     Y+  +E  +L+ +  ++  ES++ L E S + Y+  V  R++EE ER    L   + + I   +  +L++  +K  + E+  SG  HM++N    D+  +  L++          +   +Y LR   K  V + G    +NP D +       Q  LDLK   D  +++ F  D  F +TI   FE FLN     P EYL+ F+D KL+ G K LTE+ +E I+DK M LFRF+  KDVFE +Y + LA+RLL  KS   D+EK M+ KLK ECG  +T K+E MF D+  S     +F      Q++    ++   +++ V V+    WP+   +   NIP         F  FY   H+GR+L  +  +G+  +    Y P  +++                    LQVS FQ  +L+ FN   +    + ++++   I    L + L SL+ GK  QRVL K P S ++ +  +F  N+ F  KL ++K   +  K+ +   E++ T ++V  DR+  ++  IVR+MKS + ++H  LV +V ++LR     S   IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:  152 WDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHL---ISKVREDVLISLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLNMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKT-IVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLY-LREQGKALVSEEGE--GKNPVDYI-------QGLLDLKTRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLTEQEVEYILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKDMSISNTTMDEFR-----QHLQSTGVSLGGVDLTVRVLTTGYWPTQAATPKCNIPPSPRHAFEVFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPIKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREK--CVFEEIQQETDIPERELVRALQSLACGKTTQRVLTKEPKSKEIENGHMFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLRVRFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 886
[Close]
BLAST of Cullin vs. Ensembl Sea Lamprey
Match: cul4b (cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208])

HSP 1 Score: 386.341 bits (991), Expect = 4.234e-124
Identity = 235/578 (40.66%), Postives = 346/578 (59.86%), Query Frame = 3 
Query:  192 NWLILEQAIHKIFNNSFIETNLESLYRIVESF-NPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLI-NKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGI 1919
             W  L++A+  I N++ I+ NLE LY+ VE+  + +++ +++  LRQ+C  H+       +       +FL HI   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R   ++  L+ N+ I   L  I  +R G + D SL +++  M  DL +YQ  +E ++L E    Y+ E +R ++E    +YL +VN RL+EE++R   YL   S +  L   +   +L  HL  +L+ G  ++++ N I  L LLY L       S    GI +L  ++ +Y+   GT IV NP    EKDK M Q  LD K  +D +VE CF+    F   +++ FE F+N R NKPAE +AK++DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QN    D N  NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++PSLG C+++  F +G+KELQVS FQ +VLL FN   E  L   D+  A GI
Sbjct:   59 TWQKLQEAVQAIQNSTSIKYNLEELYQAVENLCSYKISAKLYLQLRQVCEEHIRAQIQHFWAGSMDSVLFLKHIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRTHVVSDRLVQNRTIDGLLLLIERERSGETVDRSLLRSLLSMLSDLQIYQDCFEQRFLVETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEESDRIITYLD-QSTQKSLIATVEKQLLGEHLTAILQKGAANLLDENRIPELSLLYQLF------SRVKGGIQVLLQHWADYIKVFGTTIVVNP----EKDKTMVQELLDFKEKVDVIVEVCFQRSDKFINAMKEAFETFINKRLNKPAELIAKYVDSKLRAGNKEATDEELERLLDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGGAFTSKLEGMFKDMELSKDIMIQFKQYMQNQN----DAN--NIELTVNILTMGYWPTYTPME-VHLPPEMVKLQEVFKTFYLGKHSGRKLQWQPSLGHCVLKSEFKEGKKELQVSLFQTLVLLMFNEGEEFSL--EDIRTATGI 616
[Close]
BLAST of Cullin vs. Ensembl Sea Lamprey
Match: cul1b (cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887])

HSP 1 Score: 210.69 bits (535), Expect = 5.706e-58
Identity = 190/677 (28.06%), Postives = 322/677 (47.56%), Query Frame = 3 
Query:  399 LNH-ITTSWNEYCMKIEIIRSIMLFVDRKFW------SNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMME---NNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKM-TQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARP--------NKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLR--FEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDD-----LFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            L+H  T  W +Y    +++  I  +++R  W           +   + +A+  WR+  +  PL NK++    LK I  +R G + +  L   V   +  L +Y+  +E ++L +   +Y++ES   L +   T+Y+    TRL EE  R Q+YL  +S   +L  +   ++++ HL+    S F ++++   N D+            L S+  D  G+  L++  + ++   G   +E   +    D K+  Q  LD+    +++V   F  D  F  ++      F+N           +K  E LA++ DS L+  +KN  E  +E  +++VM +F++I  KDVF+ FY K LAKRL+   SA  D E +M+ KLK  CG  YT K++ MF DI  S+ L++QF   N L N        ++++ ++ V+ + +WP    S    +P  +      F+ FY   H+GRKL   ++ S G  +   +  K R  LQ S FQ  VLLQ+N   E   T   L +   I   T    +  L +    ++L     +T V + D     L      + +K  ++  N     E K+EQ+ T + +  DR+  +   IVR+MK  + ++H QL+ +VL +L  RF  +   IKK I+ LIE++Y+ R       Y Y+A
Sbjct:   87 LSHKCTVQWEDYRFSSKVLNGICSYLNR-HWVRRECDEGRKGIYEIYSLALVTWREC-LFKPL-NKQVTNAVLKLIEKERTGETINTRLISGVVGSYATLSVYKEAFESQFLLDTERFYTRESTDFLSQNPVTEYMKKAETRLLEEQRRVQVYLH-ESTHDELARKCEQVLIEKHLENFY-SEFQNLLDDDKNEDL-------ARMYSLVSRILD--GLGELKSLLETHIHNQGLSAIEKCGEGALNDPKIYVQTILDVHKKYNALVMSAFNNDAGFVASLDKACGRFINTNAVTKMAQTSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQRFYAKMLAKRLVNHNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF--KNHLAN-----SEPLDLDFSIQVLSSGSWP-FQQSCTFALPSELERSHQRFTTFYSSQHSGRKLSWLYQLSKGELVTNCF--KNRYTLQASTFQMAVLLQYNS--EDAYTVQQLHENTQIKMKTKDILVQVLQILLKSKLLVLEDENTNVDEVDLQPETLIRLFLGYKNKKLRVNINVPMKAEQKQEQETTHKNIEEDRKLVIQAAIVRIMKMRKVLKHQQLLAEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERVDGEKDTYSYLA 737
[Close]
BLAST of Cullin vs. Ensembl Sea Lamprey
Match: cul1b (cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887])

HSP 1 Score: 210.305 bits (534), Expect = 1.461e-57
Identity = 194/695 (27.91%), Postives = 326/695 (46.91%), Query Frame = 3 
Query:  375 DDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFW------SNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL--------------YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKM-TQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARP--------NKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLR--FEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDD-----LFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            +D  DE  L   T  W +Y    +++  I  +++R  W           +   + +A+  WR+  +  PL NK++    LK I  +R G + +  L   V   +++L L              Y+  +E ++L +   +Y++ES   L +   T+Y+    TRL EE  R Q+YL  +S   +L  +   ++++ HL+    S F ++++++              L S+  D  G+  L++  + ++   G   +E   +    D K+  Q  LD+    +++V   F  D  F  ++      F+N           +K  E LA++ DS L+  +KN  E  +E  +++VM +F++I  KDVF+ FY K LAKRL+   SA  D E +M+ KLK  CG  YT K++ MF DI  S+ L++QF   N L N        ++++ ++ V+ + +WP    S    +P  +      F+ FY   H+GRKL   ++ S G  +   +  K R  LQ S FQ  VLLQ+N   E   T   L +   I  D L + L  L   K   +L     +T V + D     L      + +K  ++  N     E K+EQ+ T + +  DR+  +   IVR+MK  + ++H QL+ +VL +L  RF  +   IKK I+ LIE++Y+ R       Y Y+A
Sbjct:  107 EDLMDEGVLKFYTQQWEDYRFSSKVLNGICSYLNR-HWVRRECDEGRKGIYEIYSLALVTWREC-LFKPL-NKQVTNAVLKLIEKERTGETINTRLISGVVGSYVELGLNEDDLHAKGPTLSVYKEAFESQFLLDTERFYTRESTDFLSQNPVTEYMKKAETRLLEEQRRVQVYLH-ESTHDELARKCEQVLIEKHLENFY-SEFQNLLDDD----KNEDLARMYSLVSRILD--GLGELKSLLETHIHNQGLSAIEKCGEGALNDPKIYVQTILDVHKKYNALVMSAFNNDAGFVASLDKACGRFINTNAVTKMAQTSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQRFYAKMLAKRLVNHNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQF--KNHLAN-----SEPLDLDFSIQVLSSGSWP-FQQSCTFALPSELERSHQRFTTFYSSQHSGRKLSWLYQLSKGELVTNCF--KNRYTLQASTFQMAVLLQYNS--EDAYTVQQLHENTQIKMDILVQVLQILLKSK---LLVLEDENTNVDEVDLQPETLIRLFLGYKNKKLRVNINVPMKAEQKQEQETTHKNIEEDRKLVIQAAIVRIMKMRKVLKHQQLLAEVLNQLSSRFKPRVPVIKKCIDMLIEKEYLERVDGEKDTYSYLA 775
[Close]
BLAST of Cullin vs. Ensembl Sea Lamprey
Match: cul2 (cullin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-8032])

HSP 1 Score: 193.741 bits (491), Expect = 3.978e-52
Identity = 182/668 (27.25%), Postives = 297/668 (44.46%), Query Frame = 3 
Query:  492 NNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFI---------DLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDS---------------------------IRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLD--LKVHLDSV--VEKCFKGDMSFYKTIRDCFEAFLNAR-PN---KPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVN--IEMNVNVICNATWP-SLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVR-GYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXX-XXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKE--LRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ++  LM   ++A+ +WR + I  PL    + + LK+I N R G + +  +   V   F+          L  YQ  +E  +L E   Y+ QE+ R L+  + + Y+  V  RL +E  R + YL   S                           +R +LRD + N+     L   +     HM+                                   +E++ + G   + N + +      M   F++  L+VH   V  +     GD  F   +     A +N R P    K  E LAK+ D  L+   K +TE  ++  +   + +F++I  KDVF+ FY + LAKRL+ G S  +D+E++M+ KLK  CG  +T K+  M++D+  S  L+ +F       N I +    ++  +   + V+    WP S   S    IPQ +      F  FY    NGRKL +   L T  ++  Y PK      V+ +Q  VLL FNG  +  +TY +LE +  ++   L KT+ SL      +++N      +++ + +F  N  F  K TK K      K   ++E + T   V  DR+ +L   IVR+MKS + ++H  L+ +V+ +   RF    S IKK IE LI++ YI R+Q+++  Y+YVA
Sbjct:  130 SSEQLMEIGELALDIWRRLMIE-PLEGSLVRVLLKEIKNDRSGENPNQKVIHGVINSFVHVEQYKKKFPLKFYQDVFESAFLVETGEYFKQEASRLLQTCNCSQYMQQVLGRLKDEEVRCRKYLHPSSYSKVISECQQRMVADHLQFLHSECQTIVRQELRDDMANMYT---LLRTVPQALQHMVTEQ--------------------------------QEHIRQEGLKAISNLSHE-----NMPTQFVESVLEVHSKYVQLITSVLSGDQQFMSALDKACSAVVNYREPKSLCKSPELLAKYCDGMLKKTAKGMTENEVDDKLSNSIVVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEESMINKLKQACGYEFTSKLHRMYTDMSLSADLNNKFG------NFIKEQETPIDLGVGFQIYVLQAGAWPLSQLPSTPFVIPQELEKCVRMFEIFYNDSFNGRKLTWLHYLCTGEMKMNYLPKPYVA-TVTTYQMGVLLAFNGAEQ--VTYRELEYSTQLNERELVKTIRSLI---DVKLVNSSGKEDEITPECIFSLNMEFSSKRTKFKITSAMQKDTPQQEVEQTRSAVDEDRKMYLKAAIVRIMKSRKVLKHNALIQEVISQSRARFIPSVSMIKKCIEDLIDKQYIERNQNSTDEYNYVA 744
[Close]
BLAST of Cullin vs. Ensembl Yeast
Match: CUL3 (Ubiquitin-protein ligase; forms a complex with Elc1p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; cullin family member with similarity to Cdc53p and human CUL3 [Source:SGD;Acc:S000003235])

HSP 1 Score: 124.405 bits (311), Expect = 9.998e-30
Identity = 168/739 (22.73%), Postives = 314/739 (42.49%), Query Frame = 3 
Query:  213 AIHKIFNNSFIETNLESLYRIVESFNPELNTE---IFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLC--LKQIHNQRDGISSDLSLSKAVAQMFIDL-----DLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMM--ENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNY----FKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKV--MTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVN-IEMNVNVICNATWPSLGGSKL---LNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQ-----AHLDCCIVRLMKSHRSIEHTQLVTDVLK--ELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            AI  I+++   + + E +Y+ +  +   LN +   ++N L+   ++ ++     + KD++ D  FL  +   W   C   +I   +M+++D+ +   N   M  +DM + L+R   +     +    L   +++I N     S   SL K +  M   L       +   +EP  +     YY++  + +L  L+  + L  +      E+     +L+ DS   +L+  L N+++   L ++++   +  M   N  +       +  +       +S   YI +N     F E   K G   +   ++ VE  +    +FL+  +   SV      GD+S    + D F  + +     P+EYL+ ++D  ++   K    E +++  D +    L   +T KD+FE  Y K L++RLL  +S  V+ EK M++ +K   G  +T K+EIM  DI  S  + + F  S          +N +  +     V+   +WP    + +   +++P  M  +   F  +Y   +  R L++   L    +   F  G  E+  S +  ++ L F    E  LT  ++ +   I  D +K  ++S+S     ++L K  SS  +     F  N  F     K+K   I      ++          D         L   IVR+MK+   + H QL+    K  + R  L  S +K+ I+ LIE++YI R+  + S YHY++
Sbjct:   32 AIDHIYSDDMADLSFEQVYKTI--YTIVLNKKGPILYNRLKDYLIQKLALLRETIVKDNTHDYEFLGTMARLWEVQCHCFKITGDLMMYMDKVYCKPNRC-MEVYDMCLDLFRIEILQKCSSSLISALISDIERIRNLGSVDSEHTSLWKVLIGMMETLHDNRDSFFLTDFEPVLISATEEYYNKAIDIEL--LTPIESLEKIRKLRQFESMLDSSFLNVDS-HNKLKTVLENVLIWGKLSDIIEDLTHEAMVISNGKLLQEIYDLSSEEKYRVTVIESIKSYINKNAINIPFNEGNRKKGQNAITWSSEIVELYRSQ-HSFLE-SIDFGSVRLNNLTGDVS-NAILGDVFSMYFSKEGALPSEYLSTYVDHCMKR-TKEKDAEIVKIKQDLLDSTKLIGLLTEKDIFEKIYKKQLSRRLLQQRS-LVEIEKWMVQMIKKVLGTFFTSKLEIMLRDISLSSEMYQAFQHST---------INSIEYLSFAPQVLTRTSWPFQSTNPIDEGISLPPRMSQILAGFEGYYSLKYKERVLKWAHHLSVIEIGCQFNSGYYEISFSVYAGVIFLLFEDYEE--LTLGEIYELTHIPIDDVKSLVMSMSTIPRCKILKKSSSSGNMK----FSVNYFFSSPNRKVKVPVIACPLPSQKSDNLATASSVDTYDNEIVMELSAIIVRIMKTEGKLSHQQLLERTTKRTQSRLSLTPSILKRSIQLLIEKEYIQRNADDPSYYHYLS 744
[Close]
BLAST of Cullin vs. Ensembl Yeast
Match: CDC53 (Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation; human homolog CUL1 can complement yeast cdc53 null mutant [Source:SGD;Acc:S000002290])

HSP 1 Score: 121.324 bits (303), Expect = 9.954e-29
Identity = 178/737 (24.15%), Postives = 320/737 (43.42%), Query Frame = 3 
Query:  363 KLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRK---FWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFID--------LDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTL------------IVENPNDDVEKDKKMTQNFLDLKVHLDSVVE----------KCFKGDMSFYKTIRDCFEAFLN----ARP--------NKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNI-EMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPK-GRKELQ--VSEFQCMVLLQFNGL-------VEMFLTYTDLEKAVGIDP--------------DTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLF-----GFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKE--LRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K +K  +   +FLNH     N Y ++ E  RS     D K   F  N   LM++ ++     +D+ I   L   ++ L  +    QR  IS+ +   K++  + ID        L++Y + +E  +L + + YY+Q +   L++ S T+Y+   +  +  E +   +Y   D  +  L   L  +++  H+ E L++ F  +++  DI  +  LY L +       D + I  + + F+ YV K+G              I++N N + +K   MT + L  K ++  ++E          + F  D+   K + +   AF+N    A P        +K +E LAK+ D  L+   K   E A ++  + ++T+F+++T KD FE  Y +  AKRL+ G S   + E+ ++++L+      YT K+  MF DI    RLSK   D  ++    + D +K    ++   V+    WP         +P+ ++         Y + HNGR L++   L    ++    K GR      V+ FQ  +LL +N         ++   + T    A  + P              D L K      + +  + L    +      +D+      G ++N  +KL   +  + +  E +            +RQ  L+ CIVR+MK+ R++ HT LV + + +   RF  K S +K+ I+ LI++ Y+ R     S Y Y+A
Sbjct:  115 KRWKRFTIGAIFLNHAFDYMNRYWVQKE--RS-----DGKRHIFDVNTLCLMTWKEVMFDPSKDVLINELL--DQVTLGREGQIIQRSNISTAI---KSLVALGIDPQDLKKLNLNVYIQVFEKPFLKKTQEYYTQYTNDYLEKHSVTEYIFEAHEIIKREEKAMTIYWD-DHTKKPLSMALNKVLITDHI-EKLENEFVVLLDARDIEKITSLYALIRR------DFTLIPRMASVFENYVKKTGENEISSLLAMHKHNIMKNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSKIFNESFPDDIPLAKALDNACGAFININEFALPAGSPKSATSKTSEMLAKYSDILLKKATK--PEVASDMSDEDIITIFKYLTDKDAFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQAANSMEYTGKITKMFQDI----RLSKILEDDFAVALKNEPDYSKAKYPDLQPFVLAENMWPFSYQEVEFKLPKELVPSHEKLKESYSQKHNGRILKWLWPLCRGELKADIGKPGRMPFNFTVTLFQMAILLLYNDADVLTLENIQEGTSLTIQHIAAAMVPFIKFKLIQQVPPGLDALVKPETQFKLSRPYKALKTNINFASGVKNDILQSLSGGGHDNHGNKLGNKRLTEDERIEKELN---------TERQIFLEACIVRIMKAKRNLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQKGYLQRGDDGES-YAYLA 815
[Close]
BLAST of Cullin vs. Ensembl Nematostella
Match: EDO35660 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKY8])

HSP 1 Score: 427.943 bits (1099), Expect = 2.036e-140
Identity = 256/598 (42.81%), Postives = 371/598 (62.04%), Query Frame = 3 
Query:  552 ITGPLINKEIVLCLKQ-IHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            +  P++ +  V  L Q I  +R G + D SL K++ +M  D+ +Y+  +E K+L+     YSQE  R ++E     YL +V+ RL EE +R   YL   S R  L   +   +L  HL  +L+ GF+++M +N I  L L+Y L   +        G+  L   F  ++ K G  IV NP    EKDK M Q  LD K  LD+++ + F     F   +++ FE+F+N RPNKPAE +AKF+DSKLR+GNK  TEE +E ++D++M +FRFI GKDV+EAFY KDLAKRLL+GKSA VD EK+ML KLK ECG  +T K+E MF D++ S+ +  QF      Q++        N++M V+++    WP+      +++P  M+  Q  F  FY   H+GRKL+++ +LG C+V+  F + +KELQVS FQ +VLL FN   E  L   D+++A G++   L++TL SL+ GK  RV+ KRP S  + D D+F FN+ F HKL +IK NQ+Q KET EE   T E+VF DRQ  +D  IVR+MK+ +++ HT LV+++  +L+FP+K +D+KKRIE LIERDY+ RD+  ++ YHYVA
Sbjct:    1 MVNPIVQRRTVDGLLQMIEKERHGEAVDRSLLKSLLRMLADIQMYEDAFESKFLEATDVLYSQEGNRYMQETDVPKYLAHVDKRLKEEMDRLIHYLD-QSTRKPLILCVEKQLLGQHLTSILQKGFDNLMLSNRIADLALMYQLFGRV------RKGMEELCAAFSGFIKKQGISIVLNP----EKDKTMVQELLDFKEQLDTMIAEAFMKSEKFVNAMKESFESFINKRPNKPAELIAKFVDSKLRAGNKEATEEELERLLDRIMVIFRFIHGKDVYEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGAAFTSKLEGMFKDMELSKDVMVQFRQYLQHQSL------PWNMDMVVSILTMGYWPTYLPMD-VHLPTEMVHYQETFKKFYLAKHSGRKLQWQNTLGHCVVKADFSEVKKELQVSLFQTLVLLMFNEGNEYSL--EDIKQATGVEDGELRRTLQSLACGKA-RVIKKRPQSKDIEDGDIFTFNKEFKHKLIRIKINQVQMKETPEENVNTTERVFQDRQYQIDAAIVRIMKTRKTLSHTLLVSELYTQLKFPVKPTDLKKRIESLIERDYMERDKEIANQYHYVA 577
[Close]
BLAST of Cullin vs. Ensembl Nematostella
Match: EDO35230 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM65])

HSP 1 Score: 299.286 bits (765), Expect = 4.814e-90
Identity = 215/703 (30.58%), Postives = 363/703 (51.64%), Query Frame = 3 
Query:  309 IFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYIT-GPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELL---KSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKE----------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKG-QRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX-XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            ++N L+Q+   H+ +   K+ KD   S +  FL+ +  +WN++   + +IR I++++DR +   N  + + +++ + L+RD  +  G + +      L  +  +R G   D    +   QM + L +     Y+  +E  +L+E+  +Y  E ++ L E S + Y+  V TR++EE+ER++ YL   +    ++     +I K H+  ++    SG  HM++++ I   +L          K    +    +R Y +E   +   ++V+  ++         QN L+LK   D  +   F  D  F + I   FE FLN     P E+L+ F+D KL+ G K  +E+ +E+++DK M LFRF+  KDVFE +Y + LAKRLL+ KS   D+EK M+ KLK ECG  +T K+E MF D+  S   +++F      Q++ +  +N + +++ V V+    WP+  G+   N+P       + F  FY  +H+GR+L  +P LGT  +   FP  +KE           Q+S +Q  +L+ FN   +   TY D+ +   I    L + L SL+ GK  QRVL+K P    ++  D+F  N+ F  KL ++K   +  K   E E++ T  +V  DR+  ++  IVR+MK+ +   H  LV +V ++L  RF      IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:   10 LYNGLKQVVTEHLED---KIRKDVVASLNNNFLDTLNAAWNDHQTSMVMIRDILMYMDRVYVQQNG-VDNVYNLGLILFRDKVVRYGNIRDHLCQTLLSLVRKERRGEVVDRMAIRNACQMLVILGIDSRHVYEEDFERPFLEESAEFYKMEGQKFLAENSASIYIQKVETRINEESERAKHYLDPSTEESVVKVVEEELIRK-HMKTIVDMENSGVIHMLKHDKI--EDLARMYRLFYRVKEGLKTVCDCMRGYLRE---QGKAVVVDEESETARNPISCIQNLLELKDRFDHFLHNGFSSDRLFKQAIGSEFEYFLNLNGKSP-EFLSLFIDDKLKKGVKGYSEQEVEVVLDKCMVLFRFLQEKDVFERYYKQHLAKRLLLQKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKDMTVSHTTNEEFR-----QHLSNSQINLLGVDLIVRVLTTGFWPTQSGNHKCNVPPQAQHAFDCFKRFYLGNHSGRQLTLQPQLGTAELNATFPPVKKEGASLGQRKHIFQMSSYQMCILMLFNS--QERWTYEDILQQTLIPERDLNRALQSLACGKATQRVLSKEPKGKDITATDVFSVNDLFTSKLHRVKIQTVLAKGESEPERKETRTKVDEDRKHEIEAAIVRIMKARKKRPHNLLVAEVTEQLKARFLPSPQVIKKRIEGLIEREYLARTPEDRKVYLYVA 694
[Close]
BLAST of Cullin vs. Ensembl Nematostella
Match: EDO37570 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFF7])

HSP 1 Score: 195.282 bits (495), Expect = 2.829e-52
Identity = 186/700 (26.57%), Postives = 324/700 (46.29%), Query Frame = 3 
Query:  378 DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFW------SNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL--------------YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMM---ENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVE----KCFKGDMSFYKTIRDCFEAFLNARP--------NKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLR--FEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGL----VEMFLTYTDLEKAVGIDP-DTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            D  DE  L   ++ W +Y    +++  +  +++R  W           +   + +A+  WR+ ++  PL NK++    L+ I  +R+G + +  L   V Q +++L L              Y++++E  +L++   +Y+ ES   L+E   T+Y+     RL EE  R  +YL  +S + +L  +   ++++ HLD +  + F +++   +N D+            L S+  D  G+  LR   + ++   G   +E   +    +     +++ + + +  +        FK D  F   +   F  F+N+          +K  E LA++ DS L+  +KN  E  +E I++ VM +F++I  KDVF+ FY   LAKRL+   SA  D E +M+ KLK  CG  YT K++ MF DI  S+ L+ +F    +       +   ++++  + V+ + +WP    S   ++P  M      F+ FY   H+GRKL   +  S G  +   +  K R  LQ S +Q  VLL FN      VE     T L+  + I     L KT L L     + V    PSS        FG+     +K  ++  N     E + EQ+ T + +  DR+  +   IVR+MK  + ++H  L+ +VL +L  RF  +   IKK I+ LIE++Y+ R +     Y Y+A
Sbjct:  103 DLMDESVLRFYSSRWEDYRFSSKVLNGVCAYLNRH-WVRRECDEGRKGIYEIYQLALVTWRE-HLFRPL-NKQVTNAVLRLIERERNGETINTRLVSGVIQCYVELGLNEEEQSSKGPALTVYKQYFESVFLEDTERFYTAESVEFLRENPVTEYMKKAEARLLEEQRRVNVYLH-ESTQDELARKCEQVLIEKHLD-IFYAEFQNLLNDDKNEDL-------GRMYSLGSRIPD--GLVQLRTLLENHICYQGLNALEKCGEQA-YNVSTPASYVIIIIFVSKMCNYYFIMSFKNDAGFVAALDKAFGKFINSNAVTKQAQASSKSPELLARYCDSLLKKSSKNPEEAELEDILNSVMVVFKYIEDKDVFQKFYANMLAKRLVQHNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNDKFKAHLA-------NTGSLDLDFTIQVLSSGSWP-FQQSWTFSLPAEMEKSHQRFTTFYSSQHSGRKLHWLYHKSKGELVTNCF--KNRYTLQASTYQMGVLLMFNTADSYTVEQIQEQTQLKMELLIQVLGILLKTKL-LLCDTCEDVSGLEPSSVL---KLFFGYK----NKKLRVNINVPMKTEQRNEQEQTHKYIEEDRKLLIQAAIVRIMKMRKMLKHQPLLAEVLSQLSSRFKPRVPTIKKCIDILIEKEYLERVEGEKDTYAYLA 769
[Close]
BLAST of Cullin vs. Ensembl Nematostella
Match: EDO49091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI48])

HSP 1 Score: 164.851 bits (416), Expect = 3.331e-42
Identity = 167/655 (25.50%), Postives = 289/655 (44.12%), Query Frame = 3 
Query:  522 MAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFID---------LDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSS-----------GIYILRNYFKEYVMKSGTLIVENPNDDVEK------DKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNAR-----PNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKL--LNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDD----LFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADR-QAHLDCCIVRLMKSHRSIEHTQLVTDVL----------KELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            +A+ +W+ + I  PL    +   L +I   R+G  +  ++     + F+          L LY+  +E   L E   YY +E+   L E   + Y+  V+ R+ +E+ R++ +L   S    +R+    ++ + H+   L++    M+                    K AD S           G++++    +++V ++G       N D +K        +     LD+      ++++ F  D +F+ ++       +N R     P+K  E LAK+ D  L+  NKNL++  ++  + +V+ +F++I  KD+F+ FY K LAKRL+   S  +D E+AM+ +LKH CG  YT ++  MF+D+  S  L+  FSD  +   +       + I  ++ V+ +  WP LG + +   +IPQ +I     F  FY    NGRKL +   L    V+  + K    L VS FQ  V+L FN  ++   T+++L     +    L + + SL      ++LNK        DDD     +  N NF  K TK+K      +++ +       +  AD    HL      +++S+    H Q   D L             RF      IKK IE LI++ Y+ R + +   Y YVA
Sbjct:  140 LALSIWKSIMIE-PLKETLVQHLLAEIRKDRNGEGTQQNVVHDTIKSFVGVQEYQSKGALSLYESEFEKPLLQETGEYYRREAADLLAENPCSVYIQKVDVRIQDEDLRARKFLHPVSYSRVIRECEARMV-EEHI-PYLQAECRQMVRGE-----------------KCADLSRMYKLLKHIPRGLHVMVTELEQHVEETGQ------NHDTQKFICFQGPFQYVDAMLDVHSKFTKLIDETFHADQAFHASLDKACTTIVNYRHDARKPSKSPELLAKYCDLILKKSNKNLSDSELDEKLGEVIIVFKYIDDKDIFQKFYSKMLAKRLIHNLSISMDAEEAMISRLKHACGYEYTNRLHWMFTDMSISSDLNSSFSDFLATAQV------NMGINFSLLVLQSGAWP-LGQTSVSPFSIPQELIRPVQMFEQFYNGKFNGRKLAWLQHLSNGEVKLNYCKRTYFLTVSTFQMAVMLLFNDKLQ--FTFSELSTLTQLLNKELTRIIQSLV---DVKLLNK------TEDDDSKEATYSLNMNFSSKRTKLKITSAVQRDSPQVVILLSTRGTADSDNWHLHLAEKPMVRSY----HLQQTNDTLFSFCLQVISQSRARFIPSVPMIKKCIEALIDKQYLDRQEGSKDEYSYVA 746
[Close]
BLAST of Cullin vs. Ensembl Nematostella
Match: EDO38761 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC24])

HSP 1 Score: 135.576 bits (340), Expect = 8.782e-33
Identity = 149/645 (23.10%), Postives = 289/645 (44.81%), Query Frame = 3 
Query:  588 CLKQIHNQRDGISSDLSLSKAVAQMFIDLD--------LYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSG----DSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENND-----IFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSF----------YKTIRDCFEAF-------------LNARP---NKPAEYLAKFLDSKLR--SGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGP-NYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSL-SVGKGQR-VLNKRP---SSTQVSDDDLFGFNENFH-------HKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVT---DVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYV 2339
             +K +H +R+G + D  L   V + +++L         +Y+  +E  Y+D    +Y  ++   L+E    +Y+ Y   +L EE +R+  YL      +S+ + L +  VN+++    + +L  G   +  N       +F L            +S +S   YI+     + +  + T+  ++        +K  +  L L     ++V++ F  D  F          +KT+ +  + F             L+ +P   ++  E LA + D  LR  + +K LT + +E  +  V+ + +++  KDVF  ++   L +RL++  SA  + E+ M+E L+    P +Y  K+  MF DI  S+ L+++F  +        +D   +   +N+ ++    W        +++P  + D       FY+++H+GRKL++   +   ++      G+ +L+V+ FQ  VL  +N      ++Y +L  A  +    L+KTL S+ S+ K +R +L   P   S    +D  +F  N++F         K  K+         T + +Q   E + A R   +   IV++MK  + I +  L T   ++LK +  P K   IK++ E LIE  Y+ RD+ + + + Y+
Sbjct:  160 AMKLVHAERNGEAFDSQLVIGVRESYVNLSSDASDKLMIYRENFEKAYIDATEEFYKAQASSYLQENGVQNYMRYAEMKLKEEEQRALRYLETRKGCNSVAV-LTECCVNVLVGSFKETILAEGPGMIAANETKKLLLMFQLMDRVKGGVDPMIQSLES---YIVTTGLNDMLAAAETITTDS--------EKYVEQLLALFNRFSAMVKEAFNDDPRFLTARDKAPQAFKTVVNDTKIFKLELPSKGKGSGALSVKPQPESRCPELLANYCDMLLRKTTYSKKLTSDEIESKLKDVLLVLKYVVNKDVFMRYHKAHLTRRLILDTSADSEMEENMVEWLRDVGMPADYINKLARMFQDIKVSEDLNQEFKRTC-------RDKGDIADSINIKILNAGAWSRASERIPVSLPTELEDCIPEVEEFYRKNHSGRKLQWHHLMSNGVITFSNKTGKFDLEVTTFQMSVLFAWNERPLDHISYENLRLATELPDSELRKTLWSMVSIPKLKRQILTCEPAVRSPKDFTDSSMFWVNQDFALIKNGKVQKRGKVNLIGRLQLSTDKAKQEENEGIVALRILRIQEAIVKIMKMRKRITNAALQTELVEILKNMFIPQKKM-IKEQTEWLIEHKYLKRDEEDINTFIYL 784
[Close]
BLAST of Cullin vs. Ensembl Medaka
Match: cul4a (cullin-4A [Source:NCBI gene;Acc:101154851])

HSP 1 Score: 464.537 bits (1194), Expect = 1.521e-153
Identity = 274/633 (43.29%), Postives = 393/633 (62.09%), Query Frame = 3 
Query:  447 IIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIV-LCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            +IRSI LF+DR +   NS L S WD  ++L+R   ++   + K  V   L+QI  +R+G + D SL +++  M  DL +Y+  +E ++L E    Y+ E +R ++E    +YL +V  RL+EEN+R   YL   S +  L   +   +L  H+  +L+ G +++++ N +  L LLY L       S    G+  L  ++++Y+   G  IV  P    EKDK M Q+ LD K  +D+V + CF  +  F   +++ FE F+N RPNKPAE +AK++DSKLR+GNK  TEE +E I+DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF     +QN         NIE+ VN++    WPS    + +++P  M+ +Q  F  FY   H+GRKL+++P+LG  +++  F +G+KELQVS FQ +VLL FN   E   +  ++  A GI+   LK+TL SL+ GK  RVLNK P    V D D F FN +F HKL +IK NQIQ KET EEQ  T E+VF DRQ  +D  +VR+MK  +++ H  LV+++  +L+FP+K  D+KKRIE LI+RDY+ RD+   + YHYVA
Sbjct:    1 MIRSIFLFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDSAVQKRTVEAILEQIELERNGETVDRSLLRSLLGMLSDLQVYKDSFEERFLAETDRLYAAEGQRLMQERDVPEYLHHVARRLEEENDRILSYLD-QSTQKPLICCVEKQLLGEHMTAILQKGLSNLLDENRVTELALLYQLF------SKVKGGLPTLLQFWRDYIKSFGGEIVCTP----EKDKDMVQDLLDFKDKMDNVAQSCFGRNEGFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQF--KQHMQN----QSEPSNIELTVNILTMGYWPSYTPME-VHLPAEMVKLQEVFKLFYLGKHSGRKLQWQPTLGHAVLKAEFKEGKKELQVSLFQTLVLLMFNEGEE--FSVEEIRAATGIEEGELKRTLQSLACGKA-RVLNKNPRGKDVEDGDRFNFNSDFKHKLFRIKINQIQMKETVEEQVNTTERVFQDRQYQIDAAVVRIMKMRKTLSHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKETPNQYHYVA 612
[Close]
BLAST of Cullin vs. Ensembl Medaka
Match: cul4b (cullin 4B [Source:NCBI gene;Acc:101161413])

HSP 1 Score: 443.351 bits (1139), Expect = 1.790e-142
Identity = 286/702 (40.74%), Postives = 421/702 (59.97%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESFN-PELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEV-FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWR-----DMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLK 2249
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+    +++ +++  LR  C  H+     + +++D+ D V FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R     D+ +    IN  ++L    I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +V+ RL+EE +R   YL   S +  L   +   +L  HL   L+ G   +++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK +DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKHECG  +T K+E MF D++ S+ +  QF      QNI        NIE+ VN++    WP+    + +++P  M+ +Q  F  FY   H+GRKL+++ +LG C+++  F +G+KELQVS FQ +VLL FN   E  L    L  A GI+   L++TL SL+ GK  RVL K P S  V D D F  N +F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  L+++V  +L+FP+K
Sbjct:  157 KLPENYTQETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCFHKVSAKLYKQLRAACEDHIKAQIDQ-FREDALDSVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRFYIISDLKVQSKTINGILLL----IERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVSKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLTQLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIMDVCFIRNEKFVNAMKEAFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQF---KQCQNIPG------NIELTVNILTMGYWPTYVPME-VHLPPEMVRLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKL--ATGIEDGELRRTLQSLACGKA-RVLTKTPKSKDVEDGDKFSCNNDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLMSEVYNQLKFPVK 829
[Close]
BLAST of Cullin vs. Ensembl Medaka
Match: cul4b (cullin 4B [Source:NCBI gene;Acc:101161413])

HSP 1 Score: 396.356 bits (1017), Expect = 1.609e-125
Identity = 281/733 (38.34%), Postives = 419/733 (57.16%), Query Frame = 3 
Query:  165 KTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESFN-PELNTEIFNNLRQLCLRHVSECAPKLYKDDST-DEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWR-----DMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            K  +N  +  W  L++A+  I N++ I+ NLE LY+ VE+    +++ +++  LR  C  H+     +  +  S  D +FL  I   W ++C ++ +IRSI LF+DR +   NS L S WDM ++L+R     D+ +    IN  ++L    I  +R+G + D SL +++  M  DL +YQ  +E ++L+E    Y+ E +R ++E    +YL +V+ RL+EE +R   YL   S +  L   +   +L  HL   L+ G   +++ N I  L LLY L       S    G+ +L  ++ EY+   G+ IV NP    EKDK M Q  LD K  +D +++ CF  +  F   +++ FE F+N RPNKPAE +AK +DSKLR+GNK  T+E +E ++DK+M +FRFI GKDVFEAFY KDLAKRLL+GKSA VD EK+ML KLKH           ++   + +  + ++++  +  +QN  +      NIE+ VN++    WP+    + +++P  + D    F            LR      T  V        KELQVS FQ +VLL FN   E  L   +++ A GI+   L++TL SL+ GK  RVL K P S  V D D F  N +F HKL +IK NQIQ KET EEQ +T E+VF DRQ  +D  IVR+MK  +++ H  L+++V  +L+FP+K +D+KKRIE LI+RDY+ RD+ NS+ Y+YVA
Sbjct:   65 KLPENYTQETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCFHKVSAKLYKQLRAACEDHIKAQIDQFREYPSQFDVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRFYIISDLKVQSKTINGILLL----IERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVSKRLEEEADRVITYLD-QSTQKPLIATVEKQLLGEHLTATLQKGLTQLLDENRIQDLSLLYQLF------SRVRGGVQVLLQHWIEYIKAFGSTIVINP----EKDKTMVQELLDFKDKVDHIMDVCFIRNEKFVNAMKEAFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKH----------GVLKPAVAHPHKHTEKYFKNKVMQNCQNIPG---NIELTVNILTMGYWPTYVPME-VHLPPEVSDEAPLFLF----------LRLFTWANTVAV--LLNVICKELQVSLFQTLVLLMFNEGEEFSL--EEIKLATGIEDGELRRTLQSLACGKA-RVLTKTPKSKDVEDGDKFSCNNDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLMSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENSNQYNYVA 753
[Close]
BLAST of Cullin vs. Ensembl Medaka
Match: cul3b (cullin-3 [Source:NCBI gene;Acc:101172920])

HSP 1 Score: 275.018 bits (702), Expect = 3.838e-80
Identity = 229/758 (30.21%), Postives = 377/758 (49.74%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYL---SGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMEN---NDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTC------------------IVRGYFPKG---RKE-LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX--XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W +L+ AI +I   +    + E LYR   +     + E ++  LR++   H+     K+ +D  +S +  FL  +  +WN++   + +IR I++++DR +   N+ + + +++ + ++RD  +    I   +    L  I  +R G   D    +   QM + L L     Y+  +E  +L+ +  ++  ES++ L E S + Y+  V  R++EE ER    L   + + I   +  +L++  +K  + E+  SG  HM++N   +D+  +  L++          +    Y LR   K  V + G    +NP D +       Q  LDLK   D  +++ F  D  F +TI   FE FLN     P EYL+ F+D KL+ G K LTE+ +E I+DK M LFRF+  KDVFE +Y + LA+RLL  KS   D+EK M+ KLK ECG  +T K+E MF D+  S     +F      Q++    ++   +++ V V+    WP+   +   NIP         F  FY   H+GR+L  +  +G+                   +V G    G   RK  LQVS FQ  +L+ FN   +   T+ ++++   I    L + L SL+ GK  QRVL K P S ++ +  +F  N+ F  KL ++K   +  K+ +   E++ T ++V  DR+  ++  IVR+MKS + ++H  LV +V ++LR     S   IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:   12 WDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHL---INKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKT-IVEMENSGLVHMLKNGKTDDLACMYKLFSRVPNGLKTMCECMSAY-LREQGKALVSEEGE--GKNPVDYI-------QGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFR-----QHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVFRRFYLGKHSGRQLTLQHHMGSADLNATFYGPIKKEDGSEVVVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKS--TFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHVFTVNDQFTSKLHRVKIQTVVAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 746
[Close]
BLAST of Cullin vs. Ensembl Medaka
Match: CUL3 (cullin-3-like [Source:NCBI gene;Acc:101170875])

HSP 1 Score: 270.781 bits (691), Expect = 1.185e-78
Identity = 225/761 (29.57%), Postives = 371/761 (48.75%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKD--DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDL-----YQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYL---SGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIV------ENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKE----------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGK-GQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXX--XXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSD--IKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W +L+ AI +I   +    + E LYR   +     + E ++  LR++   H+     K+ +D  +S +  FL  +  +WN++   + +IR I++++DR +   N+ + + +++ + ++RD  +    I   +    L  I  +R G   D    +  +QM + L L     Y+  +E  +LD +  ++  ES++ L E S + Y+  V  R++EE ER    L   + + I   +  +L++  +K  + E+  SG  HM++N+    L  +Y L       S   +G+  +      Y+ + G  +V      +NP D +       Q  LDLK   D  + + F  D  F +TI   FE FLN     P EYL+ F+D KL+ G K LTE+ +E I+DK M LFRF+  KDVFE +Y + L +RLL  KS   D+EK M+ KLK ECG  +T K+E MF D+  S     +F      Q+I     +   +++ V V+    WP+   +    IP         F  FY   H+GR+L  +  +G   +   F    K+                      LQVS FQ  +L+ FN + +    + ++++   I    L + L SL+ GK  QRVL K P S ++    +F  N+ F  KL ++K   +  K+ +   E++ T ++V  DR+  ++  IVR+MKS + ++H  LV +V ++LR     S   IKKRIE LIER+Y+ R   +  +Y YVA
Sbjct:   12 WDLLKSAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYTGLREVVTEHL---INKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNASQMLMILGLDGRSVYEEDFEGPFLDMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKT-IVEMENSGLVHMLKNSKTEDLACMYKLF------SRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYI-------QGLLDLKTRFDHFLIESFNNDRLFKQTIAGDFEYFLNLNSRSP-EYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLGRRLLSNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFR-----QHIQTTSASLSGVDLTVRVLTTGYWPTQSATPKCTIPPAPRHAFEVFRRFYLAKHSGRQLTLQHHMGGADLNATFYGAVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNIDK--FNFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHVFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 746
[Close]
BLAST of Cullin vs. Planmine SMEST
Match: SMESG000001104.1 (SMESG000001104.1)

HSP 1 Score: 1285.78 bits (3326), Expect = 0.000e+0
Identity = 665/750 (88.67%), Postives = 670/750 (89.33%), Query Frame = 3 
Query:   93 MASEFNSMHCVAQLPKKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            MASEFNSMHCVAQLPKKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFI+TNLESLYR+            F N+                 +DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQ               SQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPS  +                                 QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA
Sbjct:    1 MASEFNSMHCVAQLPKKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFIDTNLESLYRVTS----------FTNM-----------------NDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQ---------------SQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSKEE---------------------------------QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 675
[Close]
BLAST of Cullin vs. Planmine SMEST
Match: SMESG000001104.1 (SMESG000001104.1)

HSP 1 Score: 1269.6 bits (3284), Expect = 0.000e+0
Identity = 659/750 (87.87%), Postives = 662/750 (88.27%), Query Frame = 3 
Query:   93 MASEFNSMHCVAQLPKKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            MASEFNSMHCVAQLPKKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFI+TNLE                                      +DSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQ               SQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPS  +                                 QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA
Sbjct:    1 MASEFNSMHCVAQLPKKINPFLELKTVKNEFETNWLILEQAIHKIFNNSFIDTNLE--------------------------------------NDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQ---------------SQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSKEE---------------------------------QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 664
[Close]
BLAST of Cullin vs. Planmine SMEST
Match: SMESG000054773.1 (SMESG000054773.1)

HSP 1 Score: 1095.49 bits (2832), Expect = 0.000e+0
Identity = 560/596 (93.96%), Postives = 561/596 (94.13%), Query Frame = 3 
Query:  462 MLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLK 2249
            MLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPS  +                                 QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLK
Sbjct:    1 MLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSKEE---------------------------------QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLK 563
[Close]
BLAST of Cullin vs. Planmine SMEST
Match: SMESG000001104.1 (SMESG000001104.1)

HSP 1 Score: 1051.97 bits (2719), Expect = 0.000e+0
Identity = 545/596 (91.44%), Postives = 546/596 (91.61%), Query Frame = 3 
Query:  462 MLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLK 2249
            MLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQ               SQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPS  +                                 QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLK
Sbjct:    1 MLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQ---------------SQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSKEE---------------------------------QQATEEQVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKELRFPLK 548
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BLAST of Cullin vs. Planmine SMEST
Match: SMESG000001134.1 (SMESG000001134.1)

HSP 1 Score: 251.521 bits (641), Expect = 1.920e-71
Identity = 214/782 (27.37%), Postives = 385/782 (49.23%), Query Frame = 3 
Query:  195 WLILEQAIHKIFNNSFIETNLESLYRIVESFNPELNTE-IFNNLRQLCLRHVSECAPKLYKDDSTDEVFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDG-ISSDLSLSKA---VAQMFID-LDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKS---GFNHMMENNDIFXXXXXXXXXXXXXSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSA---FYKRDHNGRKLRFEPSLGTCIVRGYFPKGRKE------------------------------------------------LQVSEFQCMVLLQFNGLVEMFLTYTDLEKAVGIDPDTLKKTLLSLSVGKG-QRVLNKRP--SSTQVSDDDLFGFNENFHHKLTKIKFNXXXXXXXXXXXXXXXXXVFADRQAHLDCCIVRLMKSHRSIEHTQLVTDVLKEL--RFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA 2342
            W  L++AI +I   +    + E LYR   +   + N E ++N  + +   H+ +   ++ +  + +  FL  +   W ++   + +IR I++++DR + +      + ++  M ++RD  +    I + + V  L  +  +R G + S L L  A   +AQ+ +D L++Y+  +E  +L+++R +Y  ESER L E ++  Y+  VN  +++E +R++ +L+  +   ++   L   ++K H++ ++ +   G  HM+ N      +           K  D+ G+  + +    ++ + G  IVE    D +  +   Q  + L+   + ++      +  F   I   FE F+N     P EYL+ ++D KL+ G K ++++ ++ I DK + LFR++  KD+FE +Y + LAKRLLM KS   D EK+M+ KL  ECG  +T K+E MF D+  S+ L ++F     +        N + I++ V V+    WP+   ++ + +P    + QNAFS    FY   HNGR +  +P+LG   +  Y+ + +                                                  LQVS +Q ++L++FN   +   +Y +L +   I    L + L+SLS+ K  QR+L K P   +T+    D F  NE+F  K  KIK   I  KET+ E + T+ +V  +R+  ++  IVR+MK+ +S+ H  LV +V+++L  RF      IK+RIE L+ERDY+ R   +  +YHY+A
Sbjct:   37 WECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNN--FLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNS-TTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNK-----KYSEIALMFNLLKRVDN-GLATMSSCISRFLREEGRKIVE----DDKTPQIYIQELIYLRDRANDLLLNALLNNQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYT-----TNTLGIDLFVRVLTTGLWPTQTATQTVCMPD---EAQNAFSIYSRFYLGKHNGRVINLQPNLGNVELTAYYMQSQPSTFQSLTATDGVSEPNFNQGYQSSQIVGDVGASFNSFSGSTSQSIRKFILQVSTYQMIILMKFNRKSK--YSYEELVEETKIPERDLTRCLISLSLSKSTQRILLKEPKNKNTEFIATDTFSINESFTSKHIKIKIQSIAVKETEPEVKETKNKVDENRKYVIEATIVRIMKARKSLAHNLLVAEVIEQLKSRFVPTPQMIKQRIESLLERDYLARSDDDRKVYHYLA 793
The following BLAST results are available for this feature:
BLAST of Cullin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CUL4A1.127e-16441.70cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554][more]
CUL4B3.795e-16241.56cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555][more]
CUL4B2.731e-16041.56cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555][more]
CUL4B3.796e-16041.56cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555][more]
CUL4B4.375e-16041.56cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555][more]
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BLAST of Cullin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul-48.798e-7227.13Cullin-4 [Source:UniProtKB/Swiss-Prot;Acc:Q17392][more]
cul-35.269e-7028.05Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
cul-35.269e-7028.05Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
cul-35.269e-7028.05Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
cul-31.368e-6628.34Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
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BLAST of Cullin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cul42.300e-15440.69gene:FBgn0033260 transcript:FBtr0301355[more]
Cul42.300e-15440.69gene:FBgn0033260 transcript:FBtr0088821[more]
Cul31.222e-8129.53gene:FBgn0261268 transcript:FBtr0302158[more]
Cul31.222e-8129.53gene:FBgn0261268 transcript:FBtr0302157[more]
Cul31.222e-8129.53gene:FBgn0261268 transcript:FBtr0302156[more]
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BLAST of Cullin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul4b2.357e-16242.58cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208][more]
cul4b2.994e-14841.91cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208][more]
cul4a4.330e-13339.48cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357][more]
cul3b4.262e-7930.00cullin 3b [Source:ZFIN;Acc:ZDB-GENE-081007-1][more]
cul3a9.252e-7929.85cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376][more]
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BLAST of Cullin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnlz2.526e-16341.98DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-9... [more]
dnlz2.042e-16241.76DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-9... [more]
dnlz5.721e-16241.76DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-9... [more]
dnlz6.035e-16241.76DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-9... [more]
dnlz3.672e-16141.76DNL-type zinc finger [Source:Xenbase;Acc:XB-GENE-9... [more]
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BLAST of Cullin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cul4b8.221e-16041.56cullin 4B [Source:MGI Symbol;Acc:MGI:1919834][more]
Cul4b1.016e-15841.56cullin 4B [Source:MGI Symbol;Acc:MGI:1919834][more]
Cul4b1.016e-15841.56cullin 4B [Source:MGI Symbol;Acc:MGI:1919834][more]
Cul4a9.335e-15841.43cullin 4A [Source:MGI Symbol;Acc:MGI:1914487][more]
Cul32.478e-7929.82cullin 3 [Source:MGI Symbol;Acc:MGI:1347360][more]
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BLAST of Cullin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q13619|CUL4A_HUMAN5.412e-16441.70Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV... [more]
sp|Q13620|CUL4B_HUMAN2.101e-15941.56Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV... [more]
sp|A2A432|CUL4B_MOUSE7.110e-15841.56Cullin-4B OS=Mus musculus OX=10090 GN=Cul4b PE=1 S... [more]
sp|Q3TCH7|CUL4A_MOUSE6.530e-15741.43Cullin-4A OS=Mus musculus OX=10090 GN=Cul4a PE=1 S... [more]
sp|Q8LGH4|CUL4_ARATH2.898e-14437.62Cullin-4 OS=Arabidopsis thaliana OX=3702 GN=CUL4 P... [more]
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BLAST of Cullin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2M5W00.000e+045.01CULLIN_2 domain-containing protein OS=Opisthorchis... [more]
C7TYV20.000e+045.07Cullin OS=Schistosoma japonicum OX=6182 GN=cul-4 P... [more]
A0A4S2M5U70.000e+043.65CULLIN_2 domain-containing protein OS=Opisthorchis... [more]
C1LD650.000e+045.07Cullin OS=Schistosoma japonicum OX=6182 GN=cul-4 P... [more]
G4VC720.000e+044.53Putative cullin OS=Schistosoma mansoni OX=6183 GN=... [more]
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BLAST of Cullin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul4a9.342e-15643.29cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357][more]
cul4b1.301e-15141.15cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208][more]
ENSAMXT00000057183.13.687e-13943.13pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
cul3b3.240e-8129.83cullin 3 [Source:NCBI gene;Acc:103024283][more]
cul3a4.729e-7929.68cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376][more]
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BLAST of Cullin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
cul4b4.234e-12440.66cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208][more]
cul1b5.706e-5828.06cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887][more]
cul1b1.461e-5727.91cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887][more]
cul23.978e-5227.25cullin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-8032][more]
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BLAST of Cullin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
CUL39.998e-3022.73Ubiquitin-protein ligase; forms a complex with Elc... [more]
CDC539.954e-2924.15Cullin; structural protein of SCF complexes (which... [more]
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BLAST of Cullin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO356602.036e-14042.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352304.814e-9030.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO375702.829e-5226.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490913.331e-4225.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO387618.782e-3323.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cullin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul4a1.521e-15343.29cullin-4A [Source:NCBI gene;Acc:101154851][more]
cul4b1.790e-14240.74cullin 4B [Source:NCBI gene;Acc:101161413][more]
cul4b1.609e-12538.34cullin 4B [Source:NCBI gene;Acc:101161413][more]
cul3b3.838e-8030.21cullin-3 [Source:NCBI gene;Acc:101172920][more]
CUL31.185e-7829.57cullin-3-like [Source:NCBI gene;Acc:101170875][more]
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BLAST of Cullin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000001104.10.000e+088.67SMESG000001104.1[more]
SMESG000001104.10.000e+087.87SMESG000001104.1[more]
SMESG000054773.10.000e+093.96SMESG000054773.1[more]
SMESG000001104.10.000e+091.44SMESG000001104.1[more]
SMESG000001134.11.920e-7127.37SMESG000001134.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031169 ID=SMED30031169|Name=Cullin|organism=Schmidtea mediterranea sexual|type=transcript|length=2575bp
TGTGAACATATTTGTCTATATTTAATTATTCAATGTATGAAGTTTAGCTA
ATATTTATTAATTTAGTTAAATAATTTCAGTATTTGTTAAAAATGGCATC
TGAATTTAATTCTATGCATTGTGTTGCACAACTACCTAAGAAAATTAATC
CTTTTTTAGAACTTAAAACAGTCAAAAATGAATTTGAAACAAATTGGTTG
ATTTTAGAACAGGCGATTCATAAAATATTCAACAATTCATTCATAGAAAC
AAATTTAGAAAGTTTATATCGAATTGTTGAAAGTTTCAATCCAGAACTCA
ATACAGAAATTTTTAATAATTTGCGTCAATTATGTCTTAGACATGTCAGT
GAATGTGCACCAAAACTATATAAGGATGATAGTACAGATGAAGTATTTCT
CAATCATATTACGACATCTTGGAACGAGTATTGTATGAAAATAGAAATTA
TTAGAAGTATAATGCTTTTTGTTGATCGTAAATTTTGGTCAAATAATAGC
AGCCTAATGTCGTTTTGGGATATGGCAATGCAACTTTGGCGTGATATGTA
TATTACTGGACCACTTATTAATAAAGAAATAGTTCTTTGTTTGAAACAGA
TCCATAATCAACGCGATGGAATAAGTAGTGACTTATCCTTGTCTAAAGCT
GTTGCGCAAATGTTTATTGACCTCGATCTTTATCAAAGGTTTTGGGAGCC
TAAATATTTAGATGAAGCTCGATCATATTACAGCCAGGAAAGTGAAAGAA
AACTAAAAGAATTATCCAATACCGATTATCTTGTCTATGTGAATACAAGA
TTGGACGAAGAAAATGAGCGATCGCAAATGTATTTGTCAGGTGATAGTAT
CCGCATACAGTTGAGAGATCAACTTGTTAATATTATTCTCAAACCCCACC
TCGATGAATTGCTGAAATCTGGCTTTAATCATATGATGGAAAACAATGAT
ATATTCTATTTGGAATTATTGTATAATTTAGCTCAATTACTCAATTCAAA
ATCAGCAGATTCTTCTGGTATTTATATTCTTCGAAATTATTTTAAAGAAT
ATGTAATGAAATCTGGAACTCTCATAGTAGAGAATCCAAATGATGATGTT
GAGAAAGATAAAAAAATGACTCAAAATTTTCTCGATTTAAAAGTCCATTT
AGATTCTGTCGTGGAAAAATGTTTTAAAGGCGATATGTCATTTTATAAAA
CGATTAGAGATTGTTTTGAAGCCTTTTTGAATGCTAGACCGAATAAACCT
GCGGAATATTTGGCGAAATTCCTCGACTCGAAATTGCGATCGGGAAATAA
AAACCTGACCGAAGAGGCAATGGAATTAATTATGGACAAAGTGATGACGC
TGTTCAGATTCATCACTGGTAAAGACGTATTTGAAGCGTTTTACTTGAAG
GATTTAGCGAAACGGTTGTTGATGGGGAAATCTGCTTGCGTCGACACGGA
AAAGGCAATGTTAGAGAAATTGAAGCACGAATGCGGTCCAAATTATACGA
GGAAAATGGAAATAATGTTCAGCGATATCGATAACAGTCAACGGTTAAGC
AAGCAATTTTCCGACAGCAATTCTCTTCAAAATATAATTGATAAGGATAT
GAACAAAGTCAATATCGAAATGAACGTCAATGTCATTTGTAATGCTACAT
GGCCGTCGTTAGGAGGTTCAAAATTATTGAATATTCCTCAATACATGATT
GATATGCAAAATGCGTTTAGTGCATTTTATAAACGAGATCACAACGGACG
CAAACTGAGATTTGAACCGTCGTTAGGAACGTGTATTGTTCGAGGTTATT
TTCCTAAAGGAAGAAAGGAACTGCAGGTTTCGGAATTTCAGTGCATGGTT
TTACTGCAATTCAATGGATTAGTTGAAATGTTTTTAACGTACACGGATTT
AGAAAAGGCTGTTGGTATAGATCCGGATACTTTGAAGAAAACATTACTTT
CACTATCTGTCGGTAAAGGACAAAGAGTTTTAAATAAAAGACCATCGTCG
ACTCAAGTTAGCGATGACGATTTGTTTGGTTTCAATGAAAATTTTCATCA
TAAATTAACCAAAATAAAATTCAATCAAATTCAAACAAAGGAAACGAAAG
AAGAGCAGCAAGCTACAGAAGAGCAAGTGTTTGCTGATCGGCAGGCACAT
TTGGATTGCTGTATTGTGCGTTTAATGAAATCTCACCGTTCTATTGAACA
CACGCAACTTGTAACTGATGTTCTCAAGGAATTACGGTTTCCTTTGAAAG
GAAGTGACATTAAAAAGAGAATTGAACATCTGATTGAAAGAGATTATATT
ACTCGTGACCAATCAAATTCCAGTTTGTATCATTATGTTGCCTAATTGGT
GGGAATTTGTTTAATAAAACTGCTTAAACTTTATTTCAACGTATTGTTTT
ATTAATATTTCATGATTGATGCATGTTTTTATTTGCGTGATTTAAAGTTT
CCTGATCGATTAAATTAGTACGATTGTGATTTGTTAACTTACCAAGAAGA
AAATTATTATCGTAAATAACATGTGATATGAAAATCCTCACAATTAATTC
ACTAGACTAGATATTAAAGCTAAAG
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protein sequence of SMED30031169-orf-1

>SMED30031169-orf-1 ID=SMED30031169-orf-1|Name=SMED30031169-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=751bp
MASEFNSMHCVAQLPKKINPFLELKTVKNEFETNWLILEQAIHKIFNNSF
IETNLESLYRIVESFNPELNTEIFNNLRQLCLRHVSECAPKLYKDDSTDE
VFLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWR
DMYITGPLINKEIVLCLKQIHNQRDGISSDLSLSKAVAQMFIDLDLYQRF
WEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSG
DSIRIQLRDQLVNIILKPHLDELLKSGFNHMMENNDIFYLELLYNLAQLL
NSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLK
VHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRS
GNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACV
DTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIID
KDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAFYKRDH
NGRKLRFEPSLGTCIVRGYFPKGRKELQVSEFQCMVLLQFNGLVEMFLTY
TDLEKAVGIDPDTLKKTLLSLSVGKGQRVLNKRPSSTQVSDDDLFGFNEN
FHHKLTKIKFNQIQTKETKEEQQATEEQVFADRQAHLDCCIVRLMKSHRS
IEHTQLVTDVLKELRFPLKGSDIKKRIEHLIERDYITRDQSNSSLYHYVA
*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000136whole organism
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR033044CUL4B
IPR036390WH_DNA-bd_sf
IPR036317Cullin_homology_sf
IPR019559Cullin_neddylation_domain
IPR016158Cullin_homology
IPR011991WHTH_DNA-bd_dom
IPR001373Cullin_N
IPR016157Cullin_CS
IPR016159Cullin_repeat-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006511ubiquitin-dependent protein catabolic process
Vocabulary: molecular function
TermDefinition
GO:0031625ubiquitin protein ligase binding
Vocabulary: cellular component
TermDefinition
GO:0031461cullin-RING ubiquitin ligase complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016158Cullin homology domainSMARTSM00182cul_2coord: 170..325
e-value: 9.5E-41
score: 151.4
IPR016158Cullin homology domainPROSITEPS50069CULLIN_2coord: 140..377
score: 44.943
IPR019559Cullin protein, neddylation domainSMARTSM00884Cullin_Nedd8_2coord: 434..499
e-value: 8.2E-27
score: 105.1
IPR019559Cullin protein, neddylation domainPFAMPF10557Cullin_Nedd8coord: 437..496
e-value: 1.9E-21
score: 75.8
NoneNo IPR availableGENE3DG3DSA:1.20.1310.10coord: 139..251
e-value: 4.1E-38
score: 132.0
NoneNo IPR availableGENE3DG3DSA:1.10.10.2620coord: 261..423
e-value: 2.1E-37
score: 130.2
NoneNo IPR availableGENE3DG3DSA:1.20.1310.10coord: 25..138
e-value: 6.4E-21
score: 76.3
NoneNo IPR availablePANTHERPTHR11932CULLINcoord: 20..505
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 432..505
e-value: 2.3E-27
score: 96.7
IPR001373Cullin, N-terminalPFAMPF00888Cullincoord: 7..406
e-value: 3.4E-109
score: 366.2
IPR033044Cullin-4BPANTHERPTHR11932:SF66CULLIN-4Bcoord: 20..505
IPR016157Cullin, conserved sitePROSITEPS01256CULLIN_1coord: 478..505
IPR036390Winged helix DNA-binding domain superfamilySUPERFAMILYSSF46785"Winged helix" DNA-binding domaincoord: 417..505
IPR016159Cullin repeat-like-containing domain superfamilySUPERFAMILYSSF74788Cullin repeat-likecoord: 6..136
IPR036317Cullin homology domain superfamilySUPERFAMILYSSF75632Cullin homology domaincoord: 139..420