Protein CBR-HHAT-1

Overview
NameProtein CBR-HHAT-1
Smed IDSMED30031136
Length (bp)1687
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein CBR-HHAT-1 (SMED30031136) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein CBR-HHAT-1 (SMED30031136) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein CBR-HHAT-1 (SMED30031136) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein CBR-HHAT-1 (SMED30031136) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30031136

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30031136SMESG000001542.1 dd_Smed_v4_14970_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30031136SMESG000001542.1 dd_Smed_v4_14970_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30031136SMESG000001542.1 Contig2578newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30031136SMESG000001542.1 Contig2578uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30031136SMESG000052945.1 SMESG000027762.1 Contig2578newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30031136SMESG000052945.1 SMESG000027762.1 Contig2578uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 77.7962 bits (190), Expect = 1.062e-14
Identity = 67/257 (26.07%), Postives = 121/257 (47.08%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFC----GVFKVVIYTILWSFIHKFVHVNLILSTHEI-KRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANS 1457
            SF  ML + FY+P +    +++  +F+ Q+ +     + K   C    G+ +++ +  L   +   ++++ I S+  + + +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ PV       +   F+   +F FV  +HG   +   W A+N      EN ++ L        ++ R FSP + RR  A   + S  M I +   FL G E+  +
Sbjct:  135 SFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEH-DSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKT 390
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 77.7962 bits (190), Expect = 1.062e-14
Identity = 67/257 (26.07%), Postives = 121/257 (47.08%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFC----GVFKVVIYTILWSFIHKFVHVNLILSTHEI-KRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANS 1457
            SF  ML + FY+P +    +++  +F+ Q+ +     + K   C    G+ +++ +  L   +   ++++ I S+  + + +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ PV       +   F+   +F FV  +HG   +   W A+N      EN ++ L        ++ R FSP + RR  A   + S  M I +   FL G E+  +
Sbjct:  135 SFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEH-DSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKT 390
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 78.1814 bits (191), Expect = 1.267e-14
Identity = 67/259 (25.87%), Postives = 122/259 (47.10%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFC----GVFKVVIYTILWSFIHKFVHVNLILSTHEI-KRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIY 1463
            SF  ML + FY+P +    +++  +F+ Q+ +     + K   C    G+ +++ +  L   +   ++++ I S+  + + +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ PV       +   F+   +F FV  +HG   +   W A+N      EN ++ L        ++ R FSP + RR  A   + S  M I +   FL G E+  + +
Sbjct:  200 SFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEH-DSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYW 457
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 78.1814 bits (191), Expect = 1.267e-14
Identity = 67/259 (25.87%), Postives = 122/259 (47.10%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFC----GVFKVVIYTILWSFIHKFVHVNLILSTHEI-KRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIY 1463
            SF  ML + FY+P +    +++  +F+ Q+ +     + K   C    G+ +++ +  L   +   ++++ I S+  + + +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ PV       +   F+   +F FV  +HG   +   W A+N      EN ++ L        ++ R FSP + RR  A   + S  M I +   FL G E+  + +
Sbjct:  200 SFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEH-DSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYW 457
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Human
Match: HHAT (hedgehog acyltransferase [Source:HGNC Symbol;Acc:HGNC:18270])

HSP 1 Score: 78.1814 bits (191), Expect = 1.267e-14
Identity = 67/259 (25.87%), Postives = 122/259 (47.10%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFC----GVFKVVIYTILWSFIHKFVHVNLILSTHEI-KRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIY 1463
            SF  ML + FY+P +    +++  +F+ Q+ +     + K   C    G+ +++ +  L   +   ++++ I S+  + + +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ PV       +   F+   +F FV  +HG   +   W A+N      EN ++ L        ++ R FSP + RR  A   + S  M I +   FL G E+  + +
Sbjct:  200 SFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEH-DSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYW 457
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Celegans
Match: hhat-1 (Homolog of Hedgehog AcylTransferase [Source:UniProtKB/TrEMBL;Acc:G5EFT7])

HSP 1 Score: 103.219 bits (256), Expect = 4.248e-23
Identity = 95/359 (26.46%), Postives = 166/359 (46.24%), Query Frame = 3 
Query:  417 TILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLY----GLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSE---YKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIP-NW-KIWFCGVFKVVIYTILWSFIHKFVHVNLILST---HEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANS 1457
            +I A+A+N+    +     +  +  + A++   K    VW+S L +LY        +   PF  F F+ +    Y       S  +     +S K +    K +L M++F FY P +    ++   DF  Q+ +      NW    + GV     + ++ + +H   H  ++ +    + + +  FV+L    +  G+ F++ Y V +    L  +LD      GP C+  +TLYS++W+ FD GL+ + K YIF P+         K F +F S+GFV ++HG   HNIVWI +N+   + E   K +Y   S     E   S ++ RRI+A+   L F + +Y+   FL G ++  +
Sbjct:  124 SIAAVAYNFTPFLVAVSMAQGTVVFLTAMYA--KKTWAVWLSALPVLYVSMHETNSLSDDPFLIFTFLSYSMIHYI------SYCLEHLKGESRKEDDTILKRYLRMMFFAFYQPYLFSL-IVLYPDFERQLRERKTRQRNWLDCAWSGVRIAFWWWLMEASLHFLYHEAILKNAPYLYSLPKDQFVAL---GMAMGIFFHLKYAVIFGLPTLFAKLDNMDPLPGPICLIRVTLYSKVWREFDRGLYQFFKTYIFIPICAPTFSLPRKIFGVFISYGFVLLWHGFYHHNIVWIGLNILALFIEMGSKAIYTIESVRKWREANLSDVAFRRILAWCHILPFAIGLYSNFYFLGGSDVGAA 470
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Celegans
Match: hhat-2 (Homolog of Hedgehog AcylTransferase [Source:UniProtKB/TrEMBL;Acc:O18241])

HSP 1 Score: 65.855 bits (159), Expect = 4.320e-11
Identity = 73/314 (23.25%), Postives = 144/314 (45.86%), Query Frame = 3 
Query:  438 NYYYSSLKFLGMELIIFLIPAVFGLFKSKTLV----WISG--------LSMLYGLRYVYKYPFFNFEFIF---FHAYPYTGLLITRSISIGLTIAD--STKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQ--IYKPYIIPNWKIWFCGV---FKVVIYTILWSFIHKFVHVNLILSTHE--IKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGS---FNVTKHF-AIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENL 1295
            NY + ++ FL +++ +     +F L+    LV    W++G        L +++ +R     PF +   IF   F+ Y Y  + I   +++ L + D    KS++   +     YF +       ++  +DF+ Q   ++      W    C +   F++V +      I  F+HV  + ++ +  +  ++   +      +G  F++ YVV +        LDGF     P CI+ ++LYSRMW+ FD GL+ +LK  ++ P ++      +++ +   A+ A FG V  +HG + H I W+ ++  +   E +
Sbjct:  106 NYAFIAIGFL-LQIHMSSFQCIFVLYSFSVLVIVATWLTGGSKWTPWLLCIVFIVRATQIVPFSSGTHIFYREFNIYLYGSIKI---LNLALFLCDLKPGKSDFSKIMADSLIYFSYLPYSMTLIVRFEDFIQQFETWQKTTEICWNSVKCALWFGFRLVFWFGFIELILHFIHVQALFNSPDSLVNSLNSYEVSAIAYVAGQLFHVKYVVIFGVPAFFAALDGFRPPPPPICISRVSLYSRMWRFFDNGLYQFLKYQVYIPAMRKPLPLFWSILRSLGALCAVFGVVLAWHGTRRHFIFWVTLSATELIVERI 415
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Fly
Match: rasp (gene:FBgn0024194 transcript:FBtr0073029)

HSP 1 Score: 76.6406 bits (187), Expect = 1.582e-14
Identity = 67/273 (24.54%), Postives = 116/273 (42.49%), Query Frame = 3 
Query:  660 IGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKR-IHFVSLMGT-------QLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELAN 1454
            IG    D T+    S ++ L +  YFP +    +++ + F A+  +   + NW  +  GV +  I+   W  +   +H   I   H + R +  V +M +         F G  F++ YVV Y         DG    + P CI  I  YS MWK FD GL+ +L + I+  +    S    K  A   +F FV ++HG   + ++W  +N     +E + K       +    +R    +  +R+ A      FI + ++   F+ G E+ +
Sbjct:  195 IGAKQEDLTR---YSLVQYLGYAMYFPCLTYGPIISYQRFAAR--REDEVQNWLGFVGGVLRSAIW---WLVMQCALHYFYI---HYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFKTFTAMPEYQRWTQRHLGAVGAQRLYAMLATQLFIPAAFSNVYFIGGQEIGD 456
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Zebrafish
Match: hhat (hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE-051118-1])

HSP 1 Score: 92.4337 bits (228), Expect = 2.016e-19
Identity = 67/235 (28.51%), Postives = 113/235 (48.09%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHE-IKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPV--VKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALS 1397
             FL++  F FY P      +MT KDF  QI +P    +    F G+ ++ ++  L  F+  F++++ I S    ++ +   ++ G  L     FY+ Y+V +    LL +LDG      P C++ +  ++ MW++FD GL+ WL  YI+ P+   + G+F   K  +   +FGFVC +HG   + + W  +N      EN    L+       A+    +P   RR +A   A S
Sbjct:  222 QFLKLTAFCFYHPLFYNGPIMTYKDFSEQIERPLCKVSALHVFSGILRLCVWWCLAEFMIHFMYMHAIQSNETYLEMLPPWAMGGLALALVQFFYVKYLVLFGAVSLLVRLDGLEPPTLPRCVSIMYSFTGMWRHFDVGLYKWLIRYIYVPLGGSRHGAFR--KLLSTALAFGFVCFWHGCHDYLLYWALLNWVGVLVENAFALLFSSPPLRHAIVYCLTPRMQRRGLALISAFS 454
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Xenopus
Match: HHAT (hedgehog acyltransferase [Source:NCBI gene;Acc:100490766])

HSP 1 Score: 75.485 bits (184), Expect = 5.484e-14
Identity = 73/272 (26.84%), Postives = 121/272 (44.49%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTIL--------WSFIHKFVH---VNLILSTHEI-KRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFAS---FGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQ 1472
            SF  ML + FY+P      ++T   F  Q+       +           +IY +L        W      +H   ++ + S+H + + +   +L G  L   L FY+ Y+V Y    L+ +LDG      P C++ +  ++ +W++FD GLH +L  YI+ P   LG      H  + +S   F FVC +HG   +   W A+N     +E+  K L        A++R  SP   R+I A   ++S  + I     FL G E   +IY+++
Sbjct:  103 SFPAMLAYVFYYPVFHNGPVITYNQFAKQMQSQQKRNS---------SPLIYVLLDMARLFLWWGLAELMIHLMYMHALYSSHSLLETVSCWALGGLALAQVLFFYVKYLVLYGLPALIVRLDGLDPPALPRCVSTMYSFTGIWRSFDVGLHRFLVRYIYIP---LGGSQRGLHGMLLSSALTFIFVCCWHGAHEYLWYWAALNWIGLVAEHAGKKLLDIPVVQHAVDRTLSPKMHRQIHAALASVSTALLILTNLIFLGG-EQVGAIYWNR 361
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681])

HSP 1 Score: 71.633 bits (174), Expect = 9.330e-13
Identity = 64/266 (24.06%), Postives = 116/266 (43.61%), Query Frame = 3 
Query:  675 ADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKF-VHV----NLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANS 1457
              S +    S+  +L + FY+P      ++   +F  Q+ +P +  + +   C V K +   + W ++ +  VH+     L  S   ++ +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ P+       +    +   +F FV  +HG       W A+N      E+ ++ L         + R  SP +  R+ A   A S  M I     FL G+++  +
Sbjct:  197 TPSAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPEL-NSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKT 461
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681])

HSP 1 Score: 71.2478 bits (173), Expect = 1.180e-12
Identity = 64/266 (24.06%), Postives = 116/266 (43.61%), Query Frame = 3 
Query:  675 ADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKF-VHV----NLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANS 1457
              S +    S+  +L + FY+P      ++   +F  Q+ +P +  + +   C V K +   + W ++ +  VH+     L  S   ++ +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ P+       +    +   +F FV  +HG       W A+N      E+ ++ L         + R  SP +  R+ A   A S  M I     FL G+++  +
Sbjct:  197 TPSAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPEL-NSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKT 461
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Mouse
Match: Hhat (hedgehog acyltransferase [Source:MGI Symbol;Acc:MGI:2444681])

HSP 1 Score: 71.2478 bits (173), Expect = 1.347e-12
Identity = 64/266 (24.06%), Postives = 116/266 (43.61%), Query Frame = 3 
Query:  675 ADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKF-VHV----NLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANS 1457
              S +    S+  +L + FY+P      ++   +F  Q+ +P +  + +   C V K +   + W ++ +  VH+     L  S   ++ +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ P+       +    +   +F FV  +HG       W A+N      E+ ++ L         + R  SP +  R+ A   A S  M I     FL G+++  +
Sbjct:  197 TPSAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPEL-NSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKT 461
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BLAST of Protein CBR-HHAT-1 vs. UniProt/SwissProt
Match: sp|Q5VTY9|HHAT_HUMAN (Protein-cysteine N-palmitoyltransferase HHAT OS=Homo sapiens OX=9606 GN=HHAT PE=1 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 6.085e-14
Identity = 67/259 (25.87%), Postives = 122/259 (47.10%), Query Frame = 3 
Query:  702 SFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFC----GVFKVVIYTILWSFIHKFVHVNLILSTHEI-KRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIY 1463
            SF  ML + FY+P +    +++  +F+ Q+ +     + K   C    G+ +++ +  L   +   ++++ I S+  + + +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ PV       +   F+   +F FV  +HG   +   W A+N      EN ++ L        ++ R FSP + RR  A   + S  M I +   FL G E+  + +
Sbjct:  200 SFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEH-DSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYW 457
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BLAST of Protein CBR-HHAT-1 vs. UniProt/SwissProt
Match: sp|Q9VZU2|HHAT_DROME (Protein-cysteine N-palmitoyltransferase Rasp OS=Drosophila melanogaster OX=7227 GN=rasp PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.586e-13
Identity = 67/273 (24.54%), Postives = 116/273 (42.49%), Query Frame = 3 
Query:  660 IGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKR-IHFVSLMGT-------QLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELAN 1454
            IG    D T+    S ++ L +  YFP +    +++ + F A+  +   + NW  +  GV +  I+   W  +   +H   I   H + R +  V +M +         F G  F++ YVV Y         DG    + P CI  I  YS MWK FD GL+ +L + I+  +    S    K  A   +F FV ++HG   + ++W  +N     +E + K       +    +R    +  +R+ A      FI + ++   F+ G E+ +
Sbjct:  195 IGAKQEDLTR---YSLVQYLGYAMYFPCLTYGPIISYQRFAAR--REDEVQNWLGFVGGVLRSAIW---WLVMQCALHYFYI---HYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPNRPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFKTFTAMPEYQRWTQRHLGAVGAQRLYAMLATQLFIPAAFSNVYFIGGQEIGD 456
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BLAST of Protein CBR-HHAT-1 vs. UniProt/SwissProt
Match: sp|Q8BMT9|HHAT_MOUSE (Protein-cysteine N-palmitoyltransferase HHAT OS=Mus musculus OX=10090 GN=Hhat PE=2 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 9.421e-12
Identity = 64/266 (24.06%), Postives = 116/266 (43.61%), Query Frame = 3 
Query:  675 ADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKF-VHV----NLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANS 1457
              S +    S+  +L + FY+P      ++   +F  Q+ +P +  + +   C V K +   + W ++ +  VH+     L  S   ++ +   +L G  L   L FY+ Y+V +    LL +LDG      P C++ +  ++ MW+ FD GLH +L  Y++ P+       +    +   +F FV  +HG       W A+N      E+ ++ L         + R  SP +  R+ A   A S  M I     FL G+++  +
Sbjct:  197 TPSAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPEL-NSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKT 461
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BLAST of Protein CBR-HHAT-1 vs. TrEMBL
Match: A0A0R3PKF5 (Uncharacterized protein OS=Angiostrongylus costaricensis OX=334426 GN=ACOC_LOCUS5079 PE=3 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 3.741e-29
Identity = 116/402 (28.86%), Postives = 184/402 (45.77%), Query Frame = 3 
Query:  342 PILV-YMILSKLFRQKCSPNVFMINNTILAIAFNYYYSSLKFLGMELIIFLIPA-----VFGLFKSKTLVWISGLSMLYGLRY----VYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIP-NWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFS-----GLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELAN---SIYFSQEKASLN 1490
            P+L+ + +L  L  +  +   F++  T+L+IA   YY    F  + ++I L        V   F+SKTLVWIS L +LY   +    +   PF  F F+ +    Y    +     +     DS     K +L ML++ FY P +    ++  KDF  QI +    P NW+       ++  +  L+     F++V  +L        +  SL   Q FS     G+ F M YVV +    +  + D      GP CI  +TL+S++W+ FD GL+ + ++YIF P+ +       K F +  S+ FV ++HG   HNIVWI +N+     E   K +Y   +F    E+ FS ++ RRI+A    L F   +Y+   FL G E         F +E  +L 
Sbjct:   85 PLLIAHSLLFNLGSKLMAETPFVVTYTLLSIAACVYY----FTPLLVVISLTQGTLMFLVCNYFRSKTLVWISSLPLLYYSMHKTLDITDNPFHVFTFVSYTMLSYVSYCMDTRNGVAREQDDSLA---KKYLRMLFYTFYQPYLFSL-IVLYKDFERQIAERSTRPRNWRHSVLLAIRIAFWWTLYEVSLHFIYVEALLKNAR----YAGSLPKDQFFSLAPALGMLFQMKYVVIFGLPTVFARFDNMDPQKGPICITRVTLFSKVWREFDRGLYKFFRDYIFVPICRPTFSLQRKVFGVLVSYSFVLLWHGFYHHNIVWIILNIISLVLEMSAKSVYSFEAFRMWREKTFSDVTFRRILAALHILPFAFGLYSNIYFLGGSEAGGLFVKRMFDEETVTLR 474
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BLAST of Protein CBR-HHAT-1 vs. TrEMBL
Match: A0A0N4UBN2 (Uncharacterized protein OS=Dracunculus medinensis OX=318479 GN=DME_LOCUS8505 PE=3 SV=1)

HSP 1 Score: 129.028 bits (323), Expect = 2.493e-28
Identity = 106/368 (28.80%), Postives = 179/368 (48.64%), Query Frame = 3 
Query:  507 GLFKSKTLVWISGL-SMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIP-NWKIWFCGVFKVVIYTILWSFIHKFVHVNLILS----THEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKH-FAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSR--LFYLITFSYAHSQMSLTVNEYLRKRK 1583
             L + ++ VW+S + S+ Y L Y        F  + F +Y     +     +I   I +   + +K ++ M+++ FY P ++   +MT  +F  +I +    P  W      + +++ + +   FI  F +   IL        + +  FVSL G  +  G  F+M YVV +    +   LD     DGP CIA +TLYS+MW+ FD GL+ + K YIF P+    SF++ +    +  SF FV ++HG   HN+VWI +N+   + E   K +Y+  S     E   S I+ RRI+A+   + FI  IY+   FL G ++     F Q   +   L  R  LF L+T  Y ++Q+++ ++  +  R+
Sbjct:  101 NLVRKRSAVWLSAIPSLYYVLHYTTALASDPFLVLIFVSYTILSYISYNLEAIDGKIREEDNNSWKRYIRMMFYTFYLPYMISL-VMTYPEFERRIRERNSKPRQWNKIILFIIRIIFWWLFIEFILHFFYFEAILYDINYAANLPKNEFVSL-GMAI--GTFFHMKYVVIFGFPSIFAHLDNMQPFDGPICIARVTLYSKMWRYFDRGLYSFFKTYIFVPICA-PSFSIGRRIIGVLISFAFVLLWHGCYYHNVVWIILNILGLFVEYTGKAIYMIDSVRKWREENLSDIAFRRILAWLQIIPFIFGIYSNFYFLGGSQVG--YLFVQRIWNEETLTLRYPLFILLTLGYFYTQLTIEIDRRIEIRQ 461
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BLAST of Protein CBR-HHAT-1 vs. TrEMBL
Match: A0A454XSY3 (Hhat-1 OS=Pristionchus pacificus OX=54126 GN=PRIPAC_52105 PE=3 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 5.001e-28
Identity = 113/432 (26.16%), Postives = 204/432 (47.22%), Query Frame = 3 
Query:  315 LKLLSTIWAPILVYMILSKLFRQKCSPNVFMINNTILAIA-FNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYG-LRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIP-NWKIWFCGVFKVVIY-TILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFY-LITFSYAHSQMSLTVNEYLRKRKLKDS 1595
            L  L   +A   ++ I+SK    +    VF I  TI+A+   +Y +S L      L   LI     L ++K  VW+S L +LY  + + ++     F  + F +Y     +     +    I     ++ K +L M ++ FY P +V   ++   DF  Q+ +      +WK  F    ++  +  I    +H F   ++++ T ++ ++   + +   +  G  F++ YVV +    L  ++D     DGP C+A + LYS +W+ FD GL+ + K+Y+F P+ +       K   +F S+GFV ++HG   HNIVWI +N+   + E   K LY   S   ++  + S ++IRRI+ +   + F   +Y+   FL G ++   +Y  +      L C   F  LIT  Y ++Q  + V+ +  +R L++ 
Sbjct:   83 LGYLPVYFAHAFLFNIVSKFLPDR----VFSIVYTIVAMGGVSYAFSPLLVFYSFLQGTLIFVTSRLIRNKLAVWLSSLPILYYIMHHTHELHTDVFLVLLFVSYSLLSYISFCHETTDGPIRLEDDTQLKQYLRMFFYAFYQPYLVSL-IILYPDFERQLKERATQKRDWKHIFTFALRISFWWGITDLLLHFFYFESILVHTDDVAKLDKNTFVALGMTMGQFFHLKYVVIFGLPSLFAKIDNMQPLDGPMCLARVCLYSNVWRCFDRGLYQFFKKYLFIPICQPDFTMGKKILGVFISYGFVLLWHGFYHHNIVWILLNIAALFMEMTTKALYAQQSIRESINSRLSDLTIRRILGWLQIIPFAFGLYSNFYFLGGSKVGG-LYVDRILIEETLPCRPFFLALITIGYFYTQTCMEVDRWAEQRALEEE 508
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BLAST of Protein CBR-HHAT-1 vs. TrEMBL
Match: H3FSA5 (Hhat-1 OS=Pristionchus pacificus OX=54126 GN=WBGene00114731 PE=3 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 5.001e-28
Identity = 113/432 (26.16%), Postives = 204/432 (47.22%), Query Frame = 3 
Query:  315 LKLLSTIWAPILVYMILSKLFRQKCSPNVFMINNTILAIA-FNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYG-LRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIP-NWKIWFCGVFKVVIY-TILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFY-LITFSYAHSQMSLTVNEYLRKRKLKDS 1595
            L  L   +A   ++ I+SK    +    VF I  TI+A+   +Y +S L      L   LI     L ++K  VW+S L +LY  + + ++     F  + F +Y     +     +    I     ++ K +L M ++ FY P +V   ++   DF  Q+ +      +WK  F    ++  +  I    +H F   ++++ T ++ ++   + +   +  G  F++ YVV +    L  ++D     DGP C+A + LYS +W+ FD GL+ + K+Y+F P+ +       K   +F S+GFV ++HG   HNIVWI +N+   + E   K LY   S   ++  + S ++IRRI+ +   + F   +Y+   FL G ++   +Y  +      L C   F  LIT  Y ++Q  + V+ +  +R L++ 
Sbjct:   83 LGYLPVYFAHAFLFNIVSKFLPDR----VFSIVYTIVAMGGVSYAFSPLLVFYSFLQGTLIFVTSRLIRNKLAVWLSSLPILYYIMHHTHELHTDVFLVLLFVSYSLLSYISFCHETTDGPIRLEDDTQLKQYLRMFFYAFYQPYLVSL-IILYPDFERQLKERATQKRDWKHIFTFALRISFWWGITDLLLHFFYFESILVHTDDVAKLDKNTFVALGMTMGQFFHLKYVVIFGLPSLFAKIDNMQPLDGPMCLARVCLYSNVWRCFDRGLYQFFKKYLFIPICQPDFTMGKKILGVFISYGFVLLWHGFYHHNIVWILLNIAALFMEMTTKALYAQQSIRESINSRLSDLTIRRILGWLQIIPFAFGLYSNFYFLGGSKVGG-LYVDRILIEETLPCRPFFLALITIGYFYTQTCMEVDRWAEQRALEEE 508
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BLAST of Protein CBR-HHAT-1 vs. TrEMBL
Match: A0A0K0CXX3 (Uncharacterized protein OS=Angiostrongylus cantonensis OX=6313 PE=3 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 6.931e-28
Identity = 113/395 (28.61%), Postives = 181/395 (45.82%), Query Frame = 3 
Query:  315 LKLLSTIWAPILVYMILSKLFRQKCSPNVFMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLF-----KSKTLVWISGLSMLYGLRY----VYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIP-NWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFS-----GLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELAN 1454
            L+ L  + A  L + + SKL  +      F++  T+L+IA   YY    F    ++I L             +SKTLVWIS L +LY + +    +   PF+ F F+ +    Y    +    +I     +   S  K +L M+++ FY P +    ++  KDF  QI +    P NW+       ++  +  L+     F++V  +L        +  SL   Q FS     G+ F M YVV +    +    D      GP CI  +TL+S++W+ FD GL+++ + YIF P+ +       K F +F S+ FV ++HG   HNIVWI +N+     E + K +Y   +F    E+  S ++ RRI+A    L F   +Y+   FL G E   
Sbjct:   81 LRYLPLLIAHALFFNLGSKLMAE----TPFVVTYTLLSIASCVYY----FTPFLVVISLTQGTLMFLVCYYSRSKTLVWISSLPLLYYVMHKSPDISDSPFYIFTFVSYTILSYVSYCMD---TISGVAREQDDSLTKKYLRMMFYTFYQPYLFSL-IVLYKDFERQIAERNTRPRNWRHSVLLAIRIAFWWTLYEVSLHFIYVEALLRNLR----YAGSLPKDQFFSLAPALGMFFQMKYVVIFGLPAVFAGFDNMDPQKGPICITRVTLFSKVWREFDRGLYMFFRNYIFVPICRPTFSLQRKVFGVFVSYSFVLLWHGFYHHNIVWIILNIISLVLEMIAKSVYSFEAFRMWREKTISDVTFRRILAALHILPFAFGLYSNIYFLGGSEAGG 459
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Sea Lamprey
Match: hhat (hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE-051118-1])

HSP 1 Score: 67.781 bits (164), Expect = 1.944e-12
Identity = 65/266 (24.44%), Postives = 111/266 (41.73%), Query Frame = 3 
Query:  513 FKSKTLVWISGLSMLYGLRYVYK----------YPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNL--ILSTHE--IKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAIN 1268
             +   L W++ L +L GL+  +           Y   N  F+       T L  T S S+ L    +  +   S    L + FY+P I     M+  DFVA++ +  ++P   +     +  V     W      +H+    +L  HE  ++ +   +L    +     FY+ Y+V +    L   LDG      P C++    +S MW+NFD GLH WL  Y++ P+       + +  +  A F +V  +HG Q + + W  +N
Sbjct:  111 LRRPALCWLTNLGLLAGLQAAHWSHTQRVDRGWYESENEYFLLLFTLAMTNLRCT-SFSLELCRQGAHPAAGSSLFWPLVYTFYYPPI-----MSYCDFVARMPRLPLLPLLPLLPRLPWLAVRVAAWWVLAELMLHLGYFSVLHQHEELLESLPSATLACLAIAHVSFFYVKYLVLFGVPSLAMHLDGVQPPPLPRCVSITHGFSDMWRNFDVGLHRWLLRYVYVPLGGSQGGALRQAVSCGAVFLYVFFWHGAQAYLLFWATLN 370
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Nematostella
Match: EDO38150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDP8])

HSP 1 Score: 92.4337 bits (228), Expect = 7.456e-20
Identity = 97/388 (25.00%), Postives = 163/388 (42.01%), Query Frame = 3 
Query:  423 LAIAFNYYYSSLK------FLGMELIIFLIPAVFGLF------KSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYP--------YTGLLITRSISIGLTIA-----------DSTKSEYKSF--LEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWS-------------FIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMV-YVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLE 1445
            L +A  +YY +         +G++ +++++ AV  +F      +S +LVW + L +L  L++       NF+F F  + P         T + + R +S  L              D T     SF  L++L + FY P      +MT KDF  Q ++P  +         + K  + TILW              ++H      L+      K +   ++ G  ++S L+ ++  YVV Y  + L  +LD       P C++ + L+  MW+ FD GL+VW+K YI+ P+         +    F +F FV  +HG Q+ N+ W   N      E L   +        A E   S  + RR+ A  G+++    I +   FL G E
Sbjct:  127 LPMARRWYYPAFTVAFLVLLVGIKSVLYVV-AVCTIFYLTSKTQSVSLVWTTVLGILATLQFETAR---NFQFQFLSSNPDKNEIVLFVTLMSLLRCVSFCLECCWHRQDGAGVTRDKTDKPSPSFTLLDLLLYNFYLPLFANGPVMTYKDFHTQFHQPVQL---------LTKPELLTILWDAIRTLWWYIFLEVYLHYMYSAALVREAPVFKGLSAWTITGI-MYSQLNIFLTKYVVLYLLSGLFARLDHLDPPGAPRCVSTLYLFGDMWRYFDRGLNVWMKRYIYIPMGGSRKGIPRQITGSFLAFTFVWAWHGGQVDNLWWFIPNCLGVVIEGLAGVVSDLPEV-KAREASLSESNRRRVRALFGSVTLCCLILSNLVFLQGSE 499
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Nematostella
Match: EDO33140 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST26])

HSP 1 Score: 88.5817 bits (218), Expect = 1.412e-18
Identity = 93/389 (23.91%), Postives = 162/389 (41.65%), Query Frame = 3 
Query:  423 LAIAFNYYYSSLK------FLGMELIIFLIPAVFGLF------KSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLIT--------------------RSISIGLTIADSTKSEYKSF--LEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWS-------------FIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMV-YVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLE 1445
            L +A  +YY +         +G++ +++++ AV  +F      +S  LVW + + +L  L++       NF+F F  + P    ++                     R    G+T +D T     SF  L++L + FY P      +MT KDF  Q ++P  +         + K  + TILW              ++H      L+      K +   ++ G  ++S L+ ++V YVV YR + L  + D       P C++ + L+  MW+ FD GL+VW+K YI+ P+         +    F +F FV  +HG ++  + W+  N      E L   +        A E   S  + RR+ A  G+++      +   FL G E
Sbjct:  127 LPMARRWYYPAFTVAFLVLLVGIKSVLYVV-AVCTVFYLTSRTQSVALVWTTVIGILATLQFETAR---NFQFQFLSSNPGKNEIVLFVTLMSLLRCVSFCLECCWHRQDGAGVT-SDKTDKPLPSFTLLDLLLYNFYLPLFANGPLMTYKDFYTQFHQPVQL---------LTKPELLTILWDAIRTLWWYIFLEVYLHYMYSAALVRKDPVFKGLSVWTITGI-MYSQLNIFLVKYVVLYRLSGLFARFDHLDPPGAPRCVSTLYLFGDMWRYFDRGLNVWMKRYIYIPMGGSQKGIPRQITGSFLAFTFVWAWHGSRVDILWWVIPNWLGVVIEGLAGVVSDLPEV-KARELSLSESNRRRVRALFGSVTLCCLFLSNLVFLQGYE 499
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Medaka
Match: hhat (hedgehog acyltransferase [Source:NCBI gene;Acc:101158552])

HSP 1 Score: 71.633 bits (174), Expect = 8.155e-13
Identity = 69/275 (25.09%), Postives = 118/275 (42.91%), Query Frame = 3 
Query:  648 RSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIW-----FCGVFKVVIYTILWSFIHKFVHVNLILSTHE-IKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELAN 1454
            R IS  L    S+ +       +L + FY P      +MT K F  Q+ +     N   +          +++++  L   +  F++++ I S    I+ +   +L G  L     FY+ Y+V +    +L  LD  +    P C++ +  ++ MW++FD GL+ WL  YI+ P+       + K  +   +F F+C +HG   +   W  +N     +EN L  L+        ME+KFS    RR  A   A S  + I +   FL G  +  
Sbjct:  184 RFISFSLEQCWSSCNALVQLFWLLAYTFYHPFFYNGPIMTYKAFTEQMQRSTEENNRTTFAFSHLLLRSGRILLWWCLAECLIHFMYMHSIQSNETYIEILPPWALGGLALALVQFFYVKYLVLFGLPCMLASLDQLVPPQLPRCVSLMYSFTGMWRHFDEGLYRWLIRYIYVPLGGSRRGPLHKLLSTGLTFAFICFWHGGHDYLKYWALMNWAGVVAENGLASLFSLPRVRIMMEQKFSMAIQRRCTALLSAFSTALLILSNLVFLGGTHVGR 458
[Close]
BLAST of Protein CBR-HHAT-1 vs. Ensembl Medaka
Match: hhat (hedgehog acyltransferase [Source:NCBI gene;Acc:101158552])

HSP 1 Score: 71.2478 bits (173), Expect = 8.556e-13
Identity = 46/159 (28.93%), Postives = 74/159 (46.54%), Query Frame = 3 
Query:  978 FYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELAN 1454
            FY+ Y+V +    +L  LD  +    P C++ +  ++ MW++FD GL+ WL  YI+ P+       + K  +   +F F+C +HG   +   W  +N     +EN L  L+        ME+KFS    RR  A   A S  + I +   FL G  +  
Sbjct:  300 FYVKYLVLFGLPCMLASLDQLVPPQLPRCVSLMYSFTGMWRHFDEGLYRWLIRYIYVPLGGSRRGPLHKLLSTGLTFAFICFWHGGHDYLKYWALMNWAGVVAENGLASLFSLPRVRIMMEQKFSMAIQRRCTALLSAFSTALLILSNLVFLGGTHVGR 458
[Close]
BLAST of Protein CBR-HHAT-1 vs. Planmine SMEST
Match: SMESG000001542.1 (SMESG000001542.1)

HSP 1 Score: 1027.7 bits (2656), Expect = 0.000e+0
Identity = 505/511 (98.83%), Postives = 507/511 (99.22%), Query Frame = 3 
Query:   63 MSEETHKKKDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNVFMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVNEYLRKRKLKDS 1595
            MSEETHKKKDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNV MINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKS+ KSFLEMLYFYFYFPAIVGCRMM VKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQI+NIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVNEYLRKRK KDS
Sbjct:    1 MSEETHKKKDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNVIMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSDSKSFLEMLYFYFYFPAIVGCRMMNVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQINNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVNEYLRKRKSKDS 511
[Close]
BLAST of Protein CBR-HHAT-1 vs. Planmine SMEST
Match: SMESG000001671.1 (SMESG000001671.1)

HSP 1 Score: 457.988 bits (1177), Expect = 1.610e-156
Identity = 225/511 (44.03%), Postives = 335/511 (65.56%), Query Frame = 3 
Query:   63 MSEETHKKKDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNVFMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDTGLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVNEYLRKRKLKDS 1595
            + EET   K ER + KDY +P ISK+E    L+IW   +L+G Y+ YKL   KKT + F +   I    FGLY S  +  W+EL++L      P   Y+ +SKL R   SP +FM  N +++  FNYYYSS KF  ME++IFL  A+ GLF+ K+L+WI G   LY ++Y+  Y F+  +++F ++YPY  +L TR+IS+GL I+++ + + K  LEM ++++YFPAI+GCR+M +K+F+  IYKP +I +WK W     ++  Y  +W+ +  + H+ L + TH  +  H V   G Q+F G+H+YMVY++FY+ ++L+TQLDGFLT  GPECI HI LYSRMW             ++FRP+ KLG F +T++FA  A F FV  FHG++  N+ WI++++FQY +EN+LK+++L T  G  +E+ FSPI +RR+IA + A SF+ S++AFA F +G+ +AN++YFS    +L+ +  R      F Y+H+Q+SLTVNEYLRKRKLK +
Sbjct:   21 VPEET---KCEREKQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLENGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLISWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRQKSLIWIIGCLSLYSMKYMPDYSFYKDDYLFHNSYPYLAVLFTRAISVGLAISEAPRYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIVTHYWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMW------------SHVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYTAENILKYIFLFTWVGPYLEKTFSPIWLRRLIAAAVAASFLSSVWAFAVFQYGISIANALYFSSLNKNLSWIVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 516
[Close]
BLAST of Protein CBR-HHAT-1 vs. Planmine SMEST
Match: SMESG000001665.1 (SMESG000001665.1)

HSP 1 Score: 317.005 bits (811), Expect = 1.195e-103
Identity = 154/346 (44.51%), Postives = 225/346 (65.03%), Query Frame = 3 
Query:   63 MSEETHKKKDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNVFMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWK 1100
            + EET   K ER   KDY +P ISK+E    L+IW   +L+G Y+ YKL   KKT + F K   I    FGLY S  +  W+EL++L      P   Y+ +SKL R   SP +FM  N ++   FNYYYSS KF  ME++IFL  A+ GLF+ K+L+WI G   LY ++Y+  Y F+   ++F +++PY  +L TR+IS+GLTI+++ K + K  LEM ++++YFPAI+GCR+M +K+F+  IYKP +I +WK W     ++  Y  +W+ +  + H+ L ++TH+ +  H V   G Q+F G+H+YMVY++FY+ ++L+TQLDGFLT  GPECI HI LYSRMW+
Sbjct:   21 IPEET---KCERENQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPAYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIATHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 363
[Close]
BLAST of Protein CBR-HHAT-1 vs. Planmine SMEST
Match: SMESG000001665.1 (SMESG000001665.1)

HSP 1 Score: 256.914 bits (655), Expect = 1.068e-81
Identity = 116/254 (45.67%), Postives = 175/254 (68.90%), Query Frame = 3 
Query:  339 APILVYMILSKLFRQKCSPNVFMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGLFKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISIGLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIPNWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQLFSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWK 1100
             P   Y+ +SKL R   SP +FM  N ++   FNYYYSS KF  ME++IFL  A+ GLF+ K+L+WI G   LY ++Y+  Y F+   ++F +++PY  +L TR+IS+GLTI+++ K + K  LEM ++++YFPAI+GCR+M +K+F+  IYKP +I +WK W     ++  Y  +W+ +  + H+ L ++TH+ +  H V   G Q+F G+H+YMVY++FY+ ++L+TQLDGFLT  GPECI HI LYSRMW+
Sbjct:    9 VPFTFYIFISKLLRSYTSPKMFMFGNLLITWYFNYYYSSAKFFQMEVLIFLTFAIAGLFRHKSLIWIIGCLSLYSMKYMPAYSFYKQYYLFHNSFPYLAVLFTRAISVGLTISEAPKYDMKLVLEMSFYFWYFPAIIGCRLMVIKEFINNIYKPCVIEDWKEWLFSSVRIAAYIFIWNIVMHYCHIYLTIATHDWQNKHIVVACGVQMFYGIHYYMVYIIFYKSSYLITQLDGFLTAPGPECIVHIALYSRMWR 262
[Close]
BLAST of Protein CBR-HHAT-1 vs. Planmine SMEST
Match: SMESG000001654.1 (SMESG000001654.1)

HSP 1 Score: 154.836 bits (390), Expect = 1.029e-42
Identity = 74/153 (48.37%), Postives = 110/153 (71.90%), Query Frame = 3 
Query: 1137 YIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIAINLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSIYAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVNEYLRKRKLKDS 1595
            ++FRP+ KLG F +T++FA  A F FV  FHG++  N+ WI++++FQY +EN+LK+++L T  G  +E+ FSPI +RR+IA + A SF  S++AFA+F +G+ +AN++YFS    S + L  R      F Y+H+Q+SLTVNEYLRKRKLK +
Sbjct:  141 HVFRPIAKLGPFRITRYFAAIACFAFVVNFHGLRRDNLYWISLSIFQYTAENILKYIFLFTCVGPYLEKTFSPIWLRRLIAAAVAASFYSSVWAFAAFQYGIPIANALYFSSLNKSFSWLVERFITGSAFIYSHAQISLTVNEYLRKRKLKTA 293

HSP 2 Score: 88.5817 bits (218), Expect = 3.357e-19
Identity = 50/121 (41.32%), Postives = 68/121 (56.20%), Query Frame = 3 
Query:   63 MSEETHKKKDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLLYTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMILSKLFRQKCSPNVFMINNTIL 425
            + EET   K ER + KDY +P ISK+E    L+IW   +L+G Y+ YKL   KKT + F K   I    FGLY S  +  W+EL++L      P   Y+I+SKL R   SP +FM  N ++
Sbjct:   21 VPEET---KCEREKQKDYNVPPISKLEFAFYLLIWVFIVLRGVYEIYKLTNNKKTQKQFLKNGFIQKGSFGLYKSNNEYLWNELMELFVKGAVPFTFYIIISKLLRSYTSPKMFMFGNLLI 138
The following BLAST results are available for this feature:
BLAST of Protein CBR-HHAT-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HHAT1.062e-1426.07hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT1.062e-1426.07hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT1.267e-1425.87hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT1.267e-1425.87hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
HHAT1.267e-1425.87hedgehog acyltransferase [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
hhat-14.248e-2326.46Homolog of Hedgehog AcylTransferase [Source:UniPr... [more]
hhat-24.320e-1123.25Homolog of Hedgehog AcylTransferase [Source:UniPr... [more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rasp1.582e-1424.54gene:FBgn0024194 transcript:FBtr0073029[more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
hhat2.016e-1928.51hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
HHAT5.484e-1426.84hedgehog acyltransferase [Source:NCBI gene;Acc:100... [more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Hhat9.330e-1324.06hedgehog acyltransferase [Source:MGI Symbol;Acc:MG... [more]
Hhat1.180e-1224.06hedgehog acyltransferase [Source:MGI Symbol;Acc:MG... [more]
Hhat1.347e-1224.06hedgehog acyltransferase [Source:MGI Symbol;Acc:MG... [more]
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BLAST of Protein CBR-HHAT-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q5VTY9|HHAT_HUMAN6.085e-1425.87Protein-cysteine N-palmitoyltransferase HHAT OS=Ho... [more]
sp|Q9VZU2|HHAT_DROME1.586e-1324.54Protein-cysteine N-palmitoyltransferase Rasp OS=Dr... [more]
sp|Q8BMT9|HHAT_MOUSE9.421e-1224.06Protein-cysteine N-palmitoyltransferase HHAT OS=Mu... [more]
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BLAST of Protein CBR-HHAT-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3PKF53.741e-2928.86Uncharacterized protein OS=Angiostrongylus costari... [more]
A0A0N4UBN22.493e-2828.80Uncharacterized protein OS=Dracunculus medinensis ... [more]
A0A454XSY35.001e-2826.16Hhat-1 OS=Pristionchus pacificus OX=54126 GN=PRIPA... [more]
H3FSA55.001e-2826.16Hhat-1 OS=Pristionchus pacificus OX=54126 GN=WBGen... [more]
A0A0K0CXX36.931e-2828.61Uncharacterized protein OS=Angiostrongylus cantone... [more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
hhat1.944e-1224.44hedgehog acyltransferase [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO381507.456e-2025.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO331401.412e-1823.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein CBR-HHAT-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
hhat8.155e-1325.09hedgehog acyltransferase [Source:NCBI gene;Acc:101... [more]
hhat8.556e-1328.93hedgehog acyltransferase [Source:NCBI gene;Acc:101... [more]
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BLAST of Protein CBR-HHAT-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000001542.10.000e+098.83SMESG000001542.1[more]
SMESG000001671.11.610e-15644.03SMESG000001671.1[more]
SMESG000001665.11.195e-10344.51SMESG000001665.1[more]
SMESG000001665.11.068e-8145.67SMESG000001665.1[more]
SMESG000001654.11.029e-4248.37SMESG000001654.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031136 ID=SMED30031136|Name=Protein CBR-HHAT-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1687bp
GATTATATAAGAATTAACCCTGAGGTTTTATATTGTATTTTTTTATTAAA
TTATTGAAAATTATGTCAGAGGAAACACATAAAAAAAAAGATGAAAGAAT
AAGGAATAAAGATTACGAGATTCCTGGGATATCAAAAATTGAACTTTTAA
CTTGTCTGGTTATTTGGTTTAGTTTTCTATTAAAAGGATGTTATGATTTT
TACAAGTTGTTATACACTAAGAAAACTCTTCAGCATTTTCGGAAAGAAAT
GTTAATAGCACCATTTTATTTTGGATTATACACGAGCGCATATGACAATC
AATGGGATGAGTTACTTAAACTTCTATCAACAATATGGGCTCCTATATTG
GTTTATATGATCCTTTCAAAACTATTCCGACAAAAATGTTCTCCAAATGT
ATTCATGATCAACAATACAATACTAGCAATCGCTTTTAATTATTATTATT
CCTCTTTGAAATTTCTCGGAATGGAATTAATAATATTTCTTATTCCAGCT
GTATTCGGTTTGTTTAAATCTAAGACATTGGTTTGGATAAGCGGCCTTTC
TATGCTATACGGCCTGAGATATGTCTATAAATATCCATTTTTCAATTTTG
AGTTCATATTTTTTCATGCATATCCTTACACTGGGCTTCTAATAACTCGG
TCTATTTCAATTGGGTTAACAATTGCAGATTCTACTAAATCAGAATACAA
ATCGTTTTTAGAGATGCTTTACTTTTATTTCTACTTTCCCGCTATTGTTG
GCTGTCGAATGATGACTGTGAAAGACTTTGTGGCACAGATTTACAAACCG
TATATCATTCCAAATTGGAAAATCTGGTTTTGTGGTGTTTTCAAAGTTGT
AATTTACACAATCCTTTGGAGCTTTATTCATAAATTTGTCCACGTTAATT
TAATCTTGTCAACTCATGAAATAAAGCGCATTCATTTTGTTTCGCTCATG
GGAACCCAGCTCTTTAGCGGATTGCATTTCTACATGGTTTATGTTGTTTT
TTATAGAGGCAATTTTCTCTTGACCCAGTTAGACGGCTTTCTTACCACAG
ATGGGCCGGAATGTATTGCTCACATCACTCTCTATTCTAGAATGTGGAAA
AACTTCGATACTGGATTGCACGTTTGGTTGAAAGAATATATATTCCGTCC
AGTTGTTAAGTTAGGTTCATTTAACGTAACAAAGCACTTTGCAATTTTTG
CTTCATTCGGATTCGTCTGCATATTTCACGGAGTCCAAATCCACAACATT
GTTTGGATAGCGATAAACCTCTTTCAATATTATTCCGAAAATCTTTTAAA
GTTTCTATATCTTCACACTTCATTTGGGGCTGCTATGGAAAGGAAGTTTT
CTCCGATTTCGATACGGAGAATTATCGCATTTAGCGGAGCATTGAGTTTT
ATAATGTCAATATATGCATTTGCCTCATTTCTATTCGGTCTGGAACTTGC
CAACTCCATATATTTTTCTCAAGAGAAAGCTTCATTGAATTTGCTGTGTT
CGCGGTTATTTTATCTAATTACTTTCTCATATGCTCATTCGCAGATGTCT
CTAACTGTAAATGAATATTTGCGCAAACGGAAATTGAAGGATTCCTAATA
ATCACTGTGGAAGATATTCAAATGATTTTTCCTTTTAATGAATCAAATAC
ATTTATTTTTCTTGTTTTTAAATATATACTATTAAAC
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protein sequence of SMED30031136-orf-1

>SMED30031136-orf-1 ID=SMED30031136-orf-1|Name=SMED30031136-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=512bp
MSEETHKKKDERIRNKDYEIPGISKIELLTCLVIWFSFLLKGCYDFYKLL
YTKKTLQHFRKEMLIAPFYFGLYTSAYDNQWDELLKLLSTIWAPILVYMI
LSKLFRQKCSPNVFMINNTILAIAFNYYYSSLKFLGMELIIFLIPAVFGL
FKSKTLVWISGLSMLYGLRYVYKYPFFNFEFIFFHAYPYTGLLITRSISI
GLTIADSTKSEYKSFLEMLYFYFYFPAIVGCRMMTVKDFVAQIYKPYIIP
NWKIWFCGVFKVVIYTILWSFIHKFVHVNLILSTHEIKRIHFVSLMGTQL
FSGLHFYMVYVVFYRGNFLLTQLDGFLTTDGPECIAHITLYSRMWKNFDT
GLHVWLKEYIFRPVVKLGSFNVTKHFAIFASFGFVCIFHGVQIHNIVWIA
INLFQYYSENLLKFLYLHTSFGAAMERKFSPISIRRIIAFSGALSFIMSI
YAFASFLFGLELANSIYFSQEKASLNLLCSRLFYLITFSYAHSQMSLTVN
EYLRKRKLKDS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR004299MBOAT_fam
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0016740transferase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004299Membrane bound O-acyl transferase, MBOATPFAMPF03062MBOATcoord: 210..446
e-value: 5.1E-9
score: 35.9
NoneNo IPR availablePANTHERPTHR13285ACYLTRANSFERASEcoord: 24..494
NoneNo IPR availableTMHMMTMhelixcoord: 437..459
NoneNo IPR availableTMHMMTMhelixcoord: 20..39
NoneNo IPR availableTMHMMTMhelixcoord: 182..204
NoneNo IPR availableTMHMMTMhelixcoord: 379..401
NoneNo IPR availableTMHMMTMhelixcoord: 252..272
NoneNo IPR availableTMHMMTMhelixcoord: 88..105
NoneNo IPR availableTMHMMTMhelixcoord: 112..129
NoneNo IPR availableTMHMMTMhelixcoord: 214..231
NoneNo IPR availableTMHMMTMhelixcoord: 139..161
NoneNo IPR availableTMHMMTMhelixcoord: 292..314