FAD-dependent oxidoreductase domain-containing protein 2

Overview
NameFAD-dependent oxidoreductase domain-containing protein 2
Smed IDSMED30031126
Length (bp)1911
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of FAD-dependent oxidoreductase domain-containing protein 2 (SMED30031126) t-SNE clustered cells

Violin plots show distribution of expression levels for FAD-dependent oxidoreductase domain-containing protein 2 (SMED30031126) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of FAD-dependent oxidoreductase domain-containing protein 2 (SMED30031126) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for FAD-dependent oxidoreductase domain-containing protein 2 (SMED30031126) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30031126

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30031126h1SMcG0001655 SmedASXL_011764SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30031126h1SMcG0001655 SmedASXL_011764SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30031126h1SMcG0001655 dd_Smed_v4_12138_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30031126h1SMcG0001655 dd_Smed_v4_12138_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30031126h1SMcG0001655 dd_Smed_v4_12138_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30031126h1SMcG0001655 dd_Smed_v6_12138_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30031126h1SMcG0001655 OX_Smed_1.0.09504ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Human
Match: FOXRED2 (FAD dependent oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26264])

HSP 1 Score: 528.48 bits (1360), Expect = 3.462e-180
Identity = 266/581 (45.78%), Postives = 366/581 (62.99%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHS-DIIKFEKCNKTGKINIFL------RSIDGKTFIKYDK-------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNER----KKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP+GLQM Y++++  R+Y +FER    G+FF  +PRH  LISINKR+TG++N EFN+RHDWNSLL+ D   LFR++S+ +FP+  D+ +Y   +     + +Q+NTTI+ +  D D++      F + DQ G  ++C +L VATGLS P+  + PG  Y  GYES+++ PE + G++VLILG+GNSAFE A ++ GVTN I + S S VRL+WATHYVGD+RAINN +LDTYQLKSLDG+LE +L    I+K  K         FL      +S D  T  + D         YD VIRC GW F++ IF +     S+R+N      KK+P I+A Y S     L+  G  +HS+D+RKSAGGFIHGFRYT R +HR++E+RHH   WP     I  + +  VRR+NE S  YQMFG L D+ ++ E+  ++ ++EE+PI  LA  E  TG + +  + V   EYGR+FS    + F D+R  G    A  SNFLHPVIY Y  LPTE+++R R     LP+P  +HH+ EDF T+W      I P +RF+EN L  DL S+ AE+C    LT+
Sbjct:   33 YCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNK-----SLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTR 608          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Human
Match: FOXRED2 (FAD dependent oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26264])

HSP 1 Score: 528.48 bits (1360), Expect = 3.462e-180
Identity = 266/581 (45.78%), Postives = 366/581 (62.99%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHS-DIIKFEKCNKTGKINIFL------RSIDGKTFIKYDK-------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNER----KKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP+GLQM Y++++  R+Y +FER    G+FF  +PRH  LISINKR+TG++N EFN+RHDWNSLL+ D   LFR++S+ +FP+  D+ +Y   +     + +Q+NTTI+ +  D D++      F + DQ G  ++C +L VATGLS P+  + PG  Y  GYES+++ PE + G++VLILG+GNSAFE A ++ GVTN I + S S VRL+WATHYVGD+RAINN +LDTYQLKSLDG+LE +L    I+K  K         FL      +S D  T  + D         YD VIRC GW F++ IF +     S+R+N      KK+P I+A Y S     L+  G  +HS+D+RKSAGGFIHGFRYT R +HR++E+RHH   WP     I  + +  VRR+NE S  YQMFG L D+ ++ E+  ++ ++EE+PI  LA  E  TG + +  + V   EYGR+FS    + F D+R  G    A  SNFLHPVIY Y  LPTE+++R R     LP+P  +HH+ EDF T+W      I P +RF+EN L  DL S+ AE+C    LT+
Sbjct:   33 YCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNK-----SLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTR 608          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Human
Match: FOXRED2 (FAD dependent oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26264])

HSP 1 Score: 528.48 bits (1360), Expect = 3.462e-180
Identity = 266/581 (45.78%), Postives = 366/581 (62.99%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHS-DIIKFEKCNKTGKINIFL------RSIDGKTFIKYDK-------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNER----KKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP+GLQM Y++++  R+Y +FER    G+FF  +PRH  LISINKR+TG++N EFN+RHDWNSLL+ D   LFR++S+ +FP+  D+ +Y   +     + +Q+NTTI+ +  D D++      F + DQ G  ++C +L VATGLS P+  + PG  Y  GYES+++ PE + G++VLILG+GNSAFE A ++ GVTN I + S S VRL+WATHYVGD+RAINN +LDTYQLKSLDG+LE +L    I+K  K         FL      +S D  T  + D         YD VIRC GW F++ IF +     S+R+N      KK+P I+A Y S     L+  G  +HS+D+RKSAGGFIHGFRYT R +HR++E+RHH   WP     I  + +  VRR+NE S  YQMFG L D+ ++ E+  ++ ++EE+PI  LA  E  TG + +  + V   EYGR+FS    + F D+R  G    A  SNFLHPVIY Y  LPTE+++R R     LP+P  +HH+ EDF T+W      I P +RF+EN L  DL S+ AE+C    LT+
Sbjct:   33 YCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNK-----SLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTR 608          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Human
Match: FOXRED2 (FAD dependent oxidoreductase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26264])

HSP 1 Score: 80.8777 bits (198), Expect = 3.790e-18
Identity = 30/54 (55.56%), Postives = 42/54 (77.78%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFT 309
            YC++GAGP+GLQM Y++++  R+Y +FER    G+FF  +PRH  LISINKR+T
Sbjct:   33 YCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYT 86          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Celegans
Match: fmo-4 (Dimethylaniline monooxygenase [N-oxide-forming] [Source:UniProtKB/TrEMBL;Acc:G5EDG8])

HSP 1 Score: 62.7734 bits (151), Expect = 4.969e-10
Identity = 53/216 (24.54%), Postives = 96/216 (44.44%), Query Frame = 1
Query:  145 KYCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEF--FPNKDDLFKYFNYYGKHWKI--NIQFNTTISKIQQDSDKRFSMEDQNGSHYKCHILVVATG----LSSPHIPNIPGIHYTI--GYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLAS 762
            + C++GAG SGL       ++  + V FE+ +  G  +   P         K   G   +   +      +   DF         EF  F +   + +Y   Y +H+ +   I+FNT + +I ++   ++ +  QNG   +   L++ TG     S P + N+      +   Y+  N S   YEGKDV +LG GNSA ++A  +  +  ++T+++
Sbjct:    2 RVCVVGAGASGLPAIKACIEEGLDVVCFEKTADIGGLWNYRPGQ-------KDIGGTVMESTVVNTSKEMMAYSDFPP-----PAEFANFMHHTKVIEYIKSYAEHFGLMDKIRFNTPVKRISRNEQNKYIVSLQNGEIEEFEKLILCTGHHAEPSYPELKNLDNFKGKVVHAYDYTNTSG--YEGKDVFLLGIGNSALDIAVDIAKIAKSVTIST 203          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Zebrafish
Match: foxred2 (FAD-dependent oxidoreductase domain containing 2 [Source:NCBI gene;Acc:767722])

HSP 1 Score: 443.736 bits (1140), Expect = 2.484e-147
Identity = 238/597 (39.87%), Postives = 340/597 (56.95%), Query Frame = 1
Query:  145 KYCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQ---DSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKI-----------------------------NIFLRSIDGKTFIKYD-------KSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSK-VLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLT 1815
            +YC++GAGP+GLQMGY++ + QR+Y+I ER +  G+FF  +PRH  LISINK +TG  N+EFN+RHDWNSLL+D    LF+  S++ +P+ DD   Y + + K   + +++ T + +I+    +  + + + DQNG +Y+C +L+V+TGL  P   +  G     GYES+   PE ++ + VLILGKGNSAFE A S+ G  + I L S S VRLAW THYVGD+RA+NN +LDTYQLKSLDG++E  L  DI    +    GK                              +  + ++ G+    Y        + YD VIRC G++FN+ IF+ +  P       R + P + A Y      N++  G   HS D+R SAGGFIHGFRYT R +H+I+E R+H   WP     I+ + +  +RR+NE S TYQMFG LGDI ++      Y  +EE+P+  L      +G  +    +LV V +YG + +   G      R +   T A  SNFLHPV+Y Y  LPT++ +R R     LP+P  +HH+ EDF T W        P +RF+E+ LK DL ++ AE+C  L LT
Sbjct:   35 EYCVLGAGPAGLQMGYFLSRSQRDYIILERNAGPGSFFNIYPRHRKLISINKIYTGRRNKEFNLRHDWNSLLSDRPDLLFQRISRKLYPSADDFPHYLSLFEKELGLKVKYGTDVGRIKASDFNGHQGYVLTDQNGVNYQCRVLLVSTGLWVPQEVDFRGSDLVEGYESIPTDPEEFKDQAVLILGKGNSAFETAQSILGRASRIHLYSPSPVRLAWQTHYVGDLRAVNNELLDTYQLKSLDGLVEGRL-EDIAIVRRAKDRGKRRAAKKRNSTSTKRNEPLYLTLTELLDDQNDTNISNVTGQNLPGYHTDNFSLRQPYDRVIRCLGFRFNFSIFDGSARPPQ-SSGARGRLPGVTAWYEGRGTPNMFVLGIAAHSRDYRMSAGGFIHGFRYTVRAVHKILEQRYHNIAWPTTNIPISQLQSWILRRVNEASGTYQMFGVLGDIILLQGSHCEY--LEEFPLQALPQLSALSGRSISDHGLLVLVMQYGLNHTDTLG----PGRAESEWTKAWKSNFLHPVLYYYKTLPTDKDMRQRPVGWPLPRPEAVHHMVEDFLTEWDQPISHSQPLRRFLEHCLKTDLRAFYAESCFLLSLT 623          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Zebrafish
Match: foxred2 (FAD-dependent oxidoreductase domain containing 2 [Source:NCBI gene;Acc:767722])

HSP 1 Score: 443.736 bits (1140), Expect = 2.484e-147
Identity = 238/597 (39.87%), Postives = 340/597 (56.95%), Query Frame = 1
Query:  145 KYCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQ---DSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKI-----------------------------NIFLRSIDGKTFIKYD-------KSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSK-VLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLT 1815
            +YC++GAGP+GLQMGY++ + QR+Y+I ER +  G+FF  +PRH  LISINK +TG  N+EFN+RHDWNSLL+D    LF+  S++ +P+ DD   Y + + K   + +++ T + +I+    +  + + + DQNG +Y+C +L+V+TGL  P   +  G     GYES+   PE ++ + VLILGKGNSAFE A S+ G  + I L S S VRLAW THYVGD+RA+NN +LDTYQLKSLDG++E  L  DI    +    GK                              +  + ++ G+    Y        + YD VIRC G++FN+ IF+ +  P       R + P + A Y      N++  G   HS D+R SAGGFIHGFRYT R +H+I+E R+H   WP     I+ + +  +RR+NE S TYQMFG LGDI ++      Y  +EE+P+  L      +G  +    +LV V +YG + +   G      R +   T A  SNFLHPV+Y Y  LPT++ +R R     LP+P  +HH+ EDF T W        P +RF+E+ LK DL ++ AE+C  L LT
Sbjct:   35 EYCVLGAGPAGLQMGYFLSRSQRDYIILERNAGPGSFFNIYPRHRKLISINKIYTGRRNKEFNLRHDWNSLLSDRPDLLFQRISRKLYPSADDFPHYLSLFEKELGLKVKYGTDVGRIKASDFNGHQGYVLTDQNGVNYQCRVLLVSTGLWVPQEVDFRGSDLVEGYESIPTDPEEFKDQAVLILGKGNSAFETAQSILGRASRIHLYSPSPVRLAWQTHYVGDLRAVNNELLDTYQLKSLDGLVEGRL-EDIAIVRRAKDRGKRRAAKKRNSTSTKRNEPLYLTLTELLDDQNDTNISNVTGQNLPGYHTDNFSLRQPYDRVIRCLGFRFNFSIFDGSARPPQ-SSGARGRLPGVTAWYEGRGTPNMFVLGIAAHSRDYRMSAGGFIHGFRYTVRAVHKILEQRYHNIAWPTTNIPISQLQSWILRRVNEASGTYQMFGVLGDIILLQGSHCEY--LEEFPLQALPQLSALSGRSISDHGLLVLVMQYGLNHTDTLG----PGRAESEWTKAWKSNFLHPVLYYYKTLPTDKDMRQRPVGWPLPRPEAVHHMVEDFLTEWDQPISHSQPLRRFLEHCLKTDLRAFYAESCFLLSLT 623          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Xenopus
Match: foxred2 (FAD-dependent oxidoreductase domain containing 2 [Source:NCBI gene;Acc:100145474])

HSP 1 Score: 479.559 bits (1233), Expect = 1.871e-161
Identity = 250/582 (42.96%), Postives = 358/582 (61.51%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQ-QDSDKR-----FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIEL----------------HSDIIKFEKCNKTGKINIFLRSI--DGKTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVR-SKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP GLQ+  ++E   R+YV+ ER    G+FF  +PRH  LISINKRFTG  N EFN+RHDWNSLL+ +    F ++SKEFFP+ DD+ KY   Y     +N+ +   IS ++ + SDK      F + DQ+   ++C++L+VA+GLS P++ + PG  Y  GYE++++  + + G+ VLILG+GNSAFE A ++ G TN I +   S VRL+WATHYVGD+RAINN +LDTYQLKSLDG+LE +L                H   +K    N   + N     +  D          YD VIRC GWKF++ IF+ +++       +R K+P ++A+Y ++    L+  G  +HSIDFRKSAGGFIHGFRYT+R +HR++E R+H   W      I+ ++N  ++R+NE S  YQMFG L D+ ++ ED   + ++EE P   L   E +TG +V+ + + V + EYG++FS    + F   R  G    A  SNFLHPV+Y Y+KLP+E++++ R E   LP+P  LHHV EDF T+W      + P +RF+EN L  DL ++ AE+C    LTQ
Sbjct:   30 YCVLGAGPGGLQIARFLEDSGRDYVVLERNQVPGSFFVQYPRHRKLISINKRFTGRRNTEFNLRHDWNSLLSPNGHLRFGHYSKEFFPHADDMIKYLKDYSI--GMNVHYGANISLVRIEPSDKAWNGHYFFLTDQSRMEFRCNVLLVASGLSLPNLVDFPGSEYVEGYETVSVESQNFTGQSVLILGRGNSAFETAENILGHTNFIHMLGRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLEGDLEDLALVRDGDGKLYVTHKHYLKKSIDNTRNQTNSHSHGMPQDYMDNFAARDPYDRVIRCLGWKFDFSIFD-SSVKLKAASRQRSKYPLLKANYEAMYTRGLFVVGTASHSIDFRKSAGGFIHGFRYTARSVHRLLEQRYHHIPWKASHHPISQLLNVLLKRMNEASGLYQMFGVLADVILLGEDSNDFEYLEEVPAGILPMLEESTGRKVKDTGLFVLMMEYGKNFSGPDKDVFHYNRAIGEAGEAWRSNFLHPVVYYYNKLPSEQEMKLRPEDWPLPRPVRLHHVVEDFLTDWTGPNSHVLPLRRFLENCLLTDLRAFYAESCFLFTLTQ 608          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Xenopus
Match: foxred2 (FAD-dependent oxidoreductase domain containing 2 [Source:NCBI gene;Acc:100145474])

HSP 1 Score: 479.174 bits (1232), Expect = 6.933e-160
Identity = 253/586 (43.17%), Postives = 363/586 (61.95%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQ-QDSDKR-----FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINI-----FLRSIDGK-----------------TFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVR-SKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP GLQ+  ++E   R+YV+ ER    G+FF  +PRH  LISINKRFTG  N EFN+RHDWNSLL+ +    F ++SKEFFP+ DD+ KY   Y     +N+ +   IS ++ + SDK      F + DQ+   ++C++L+VA+GLS P++ + PG  Y  GYE++++  + + G+ VLILG+GNSAFE A ++ G TN I +   S VRL+WATHYVGD+RAINN +LDTYQLKSLDG+LE +L  D+      +  GK+ +       +SID                    F   D  YD VIRC GWKF++ IF+ +++       +R K+P ++A+Y ++    L+  G  +HSIDFRKSAGGFIHGFRYT+R +HR++E R+H   W      I+ ++N  ++R+NE S  YQMFG L D+ ++ ED   + ++EE P   L   E +TG +V+ + + V + EYG++FS    + F   R  G    A  SNFLHPV+Y Y+KLP+E++++ R E   LP+P  LHHV EDF T+W      + P +RF+EN L  DL ++ AE+C    LTQ
Sbjct:  138 YCVLGAGPGGLQIARFLEDSGRDYVVLERNQVPGSFFVQYPRHRKLISINKRFTGRRNTEFNLRHDWNSLLSPNGHLRFGHYSKEFFPHADDMIKYLKDYSI--GMNVHYGANISLVRIEPSDKAWNGHYFFLTDQSRMEFRCNVLLVASGLSLPNLVDFPGSEYVEGYETVSVESQNFTGQSVLILGRGNSAFETAENILGHTNFIHMLGRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLEGDL-EDLALVR--DGDGKLYVTHKHYLKKSIDNTRNQTNSHSHGMPQDYMDNFAARD-PYDRVIRCLGWKFDFSIFD-SSVKLKAASRQRSKYPLLKANYEAMYTRGLFVVGTASHSIDFRKSAGGFIHGFRYTARSVHRLLEQRYHHIPWKASHHPISQLLNVLLKRMNEASGLYQMFGVLADVILLGEDSNDFEYLEEVPAGILPMLEESTGRKVKDTGLFVLMMEYGKNFSGPDKDVFHYNRAIGEAGEAWRSNFLHPVVYYYNKLPSEQEMKLRPEDWPLPRPVRLHHVVEDFLTDWTGPNSHVLPLRRFLENCLLTDLRAFYAESCFLFTLTQ 716          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Xenopus
Match: ywhaq (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta [Source:Xenbase;Acc:XB-GENE-946182])

HSP 1 Score: 56.9954 bits (136), Expect = 7.603e-8
Identity = 60/233 (25.75%), Postives = 101/233 (43.35%), Query Frame = 1
Query:  154 IIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTF--FQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKIN--IQFNTTISKIQQDSDKRFSME-----DQNGSHYKC---HILVVATGLSSPHIP--NIPGIHYTIG---YESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYV 801
            ++GAG SGL        +      FER    G    +++ P  G   SI K     +++E +   D+   + DDF     N           + +YF  Y +++ +   IQF TT+  I +  D   S +     +++G   KC    IL+ +   + PH+P  + PGI    G   +      PE ++ K VL++G GNS  ++A  L  +   + L++    R AW  + V
Sbjct:    7 VVGAGASGLAAIKCCVDEGLEPTCFERSEDIGGLWRYKDNPEDGR-ASIYKSVIINTSKEMSCFSDFP--IPDDFPNYMHN---------SKIMEYFRMYAQNFSLMKYIQFKTTVCSITKSLDFPTSGQWTVTIEKDGKQNKCVFDSILICSGHHTFPHLPLTSFPGIETFKGQYMHSRDYKGPEDFKNKRVLVIGIGNSGGDIAVELSRIAKQVFLSTR---RGAWIVNRV 224          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Xenopus
Match: ywhaq (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta [Source:Xenbase;Acc:XB-GENE-946182])

HSP 1 Score: 56.6102 bits (135), Expect = 8.532e-8
Identity = 60/233 (25.75%), Postives = 101/233 (43.35%), Query Frame = 1
Query:  154 IIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTF--FQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKIN--IQFNTTISKIQQDSDKRFSME-----DQNGSHYKC---HILVVATGLSSPHIP--NIPGIHYTIG---YESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYV 801
            ++GAG SGL        +      FER    G    +++ P  G   SI K     +++E +   D+   + DDF     N           + +YF  Y +++ +   IQF TT+  I +  D   S +     +++G   KC    IL+ +   + PH+P  + PGI    G   +      PE ++ K VL++G GNS  ++A  L  +   + L++    R AW  + V
Sbjct:    7 VVGAGASGLAAIKCCVDEGLEPTCFERSEDIGGLWRYKDNPEDGR-ASIYKSVIINTSKEMSCFSDFP--IPDDFPNYMHN---------SKIMEYFRMYAQNFSLMKYIQFKTTVCSITKSLDFPTSGQWTVTIEKDGKQNKCVFDSILICSGHHTFPHLPLTSFPGIETFKGQYMHSRDYKGPEDFKNKRVLVIGIGNSGGDIAVELSRIAKQVFLSTR---RGAWIVNRV 224          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Xenopus
Match: ywhaq (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta [Source:Xenbase;Acc:XB-GENE-946182])

HSP 1 Score: 56.6102 bits (135), Expect = 9.306e-8
Identity = 60/233 (25.75%), Postives = 101/233 (43.35%), Query Frame = 1
Query:  154 IIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTF--FQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKIN--IQFNTTISKIQQDSDKRFSME-----DQNGSHYKC---HILVVATGLSSPHIP--NIPGIHYTIG---YESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYV 801
            ++GAG SGL        +      FER    G    +++ P  G   SI K     +++E +   D+   + DDF     N           + +YF  Y +++ +   IQF TT+  I +  D   S +     +++G   KC    IL+ +   + PH+P  + PGI    G   +      PE ++ K VL++G GNS  ++A  L  +   + L++    R AW  + V
Sbjct:    8 VVGAGASGLAAIKCCVDEGLEPTCFERSEDIGGLWRYKDNPEDGR-ASIYKSVIINTSKEMSCFSDFP--IPDDFPNYMHN---------SKIMEYFRMYAQNFSLMKYIQFKTTVCSITKSLDFPTSGQWTVTIEKDGKQNKCVFDSILICSGHHTFPHLPLTSFPGIETFKGQYMHSRDYKGPEDFKNKRVLVIGIGNSGGDIAVELSRIAKQVFLSTR---RGAWIVNRV 225          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Mouse
Match: Foxred2 (FAD-dependent oxidoreductase domain containing 2 [Source:MGI Symbol;Acc:MGI:106315])

HSP 1 Score: 520.39 bits (1339), Expect = 2.074e-177
Identity = 259/579 (44.73%), Postives = 368/579 (63.56%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLR---------SIDGKTFIKYDK-------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP+GLQM  ++ +  R+Y +FER S+ G+FF  +PRH  LISINKR TG++N EFN+RHDWNSLL+DD   LFR++S+ +FP+  D+ +Y   + +   +++ +NT I+ +  D D +      F + DQ G  Y+C +L+VATGL+ P + + PG  Y  GYES+++ PE + G++VLILG GNSAFE A ++ GVTN + + S S VRL+WATHYVGDVRAINN +LDTYQLKSLDG+LE +L  + +   K +K GK ++ L+         S D     + D        +YD VIRC GW F++ IF++ ++  S      KK+P I+A Y S     L+  G  +HS+D+RKSAGGFIHGFRYT R +HR++E+RHHG  WP     I  + +  +RR+NE S  YQMF  L DI ++ E+  ++ ++EE+P+  LA  E+ TG   R  + V   EYG++FS    + F  +R    +  A +SNFLHPVIY Y  LPTE+ +R R  +  LP+P  +HH+ EDF T+W      I P +RF+EN L  DL S+ AE+C    LT+
Sbjct:   24 YCVLGAGPAGLQMAAFLHRAGRDYEVFERESAPGSFFTRYPRHRKLISINKRHTGKANAEFNLRHDWNSLLSDDPHLLFRHYSQAYFPDASDMVRYLGDFARRLGLHVLYNTNITHVTLDKDPQAWNGHYFILTDQKGQVYQCSVLLVATGLAVPKLVDFPGSEYVEGYESVSVDPEDFVGQNVLILGHGNSAFETAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSLDGLLESDL--EYLALVKDSK-GKFHVTLKFLLENNSSQSADSIPLPEDDNDNFAMRVAYDRVIRCLGWTFDFSIFDQ-SLRLSSGTEFSKKYPLIKASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHGIPWPSTEYPITQLTSSIIRRVNEASGLYQMFSVLADIILLKENATAFEYLEEFPMQMLAQLEMLTGRTARHGLFVINMEYGKNFSGPEKDVFYYDRSVAHIEDAWMSNFLHPVIYYYRHLPTEQDMRFRPAQWPLPRPTAIHHIVEDFLTDWTAPVGHILPLRRFLENCLDTDLRSFYAESCFLFTLTR 598          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Mouse
Match: Foxred2 (FAD-dependent oxidoreductase domain containing 2 [Source:MGI Symbol;Acc:MGI:106315])

HSP 1 Score: 520.39 bits (1339), Expect = 2.074e-177
Identity = 259/579 (44.73%), Postives = 368/579 (63.56%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLR---------SIDGKTFIKYDK-------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP+GLQM  ++ +  R+Y +FER S+ G+FF  +PRH  LISINKR TG++N EFN+RHDWNSLL+DD   LFR++S+ +FP+  D+ +Y   + +   +++ +NT I+ +  D D +      F + DQ G  Y+C +L+VATGL+ P + + PG  Y  GYES+++ PE + G++VLILG GNSAFE A ++ GVTN + + S S VRL+WATHYVGDVRAINN +LDTYQLKSLDG+LE +L  + +   K +K GK ++ L+         S D     + D        +YD VIRC GW F++ IF++ ++  S      KK+P I+A Y S     L+  G  +HS+D+RKSAGGFIHGFRYT R +HR++E+RHHG  WP     I  + +  +RR+NE S  YQMF  L DI ++ E+  ++ ++EE+P+  LA  E+ TG   R  + V   EYG++FS    + F  +R    +  A +SNFLHPVIY Y  LPTE+ +R R  +  LP+P  +HH+ EDF T+W      I P +RF+EN L  DL S+ AE+C    LT+
Sbjct:   24 YCVLGAGPAGLQMAAFLHRAGRDYEVFERESAPGSFFTRYPRHRKLISINKRHTGKANAEFNLRHDWNSLLSDDPHLLFRHYSQAYFPDASDMVRYLGDFARRLGLHVLYNTNITHVTLDKDPQAWNGHYFILTDQKGQVYQCSVLLVATGLAVPKLVDFPGSEYVEGYESVSVDPEDFVGQNVLILGHGNSAFETAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSLDGLLESDL--EYLALVKDSK-GKFHVTLKFLLENNSSQSADSIPLPEDDNDNFAMRVAYDRVIRCLGWTFDFSIFDQ-SLRLSSGTEFSKKYPLIKASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHGIPWPSTEYPITQLTSSIIRRVNEASGLYQMFSVLADIILLKENATAFEYLEEFPMQMLAQLEMLTGRTARHGLFVINMEYGKNFSGPEKDVFYYDRSVAHIEDAWMSNFLHPVIYYYRHLPTEQDMRFRPAQWPLPRPTAIHHIVEDFLTDWTAPVGHILPLRRFLENCLDTDLRSFYAESCFLFTLTR 598          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Mouse
Match: Fmo9 (flavin containing monooxygenase 9 [Source:MGI Symbol;Acc:MGI:3606068])

HSP 1 Score: 50.8322 bits (120), Expect = 4.702e-6
Identity = 60/241 (24.90%), Postives = 102/241 (42.32%), Query Frame = 1
Query:  136 IEWKYCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGT--LISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKI--NIQFNTTISKIQQDSDKRFSMEDQ-------NGSHYKC---HILVVATGLSSPHIP--NIPGIHYTIG---YESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYV 801
            ++ +  +IGAG SGL        +      FER    G  ++ F ++ +  + SI +  T  +++E     D+   + D F     N           L  YF  Y K + +   I+F TT+  +++  D  F +  Q       +G         +LV +   + PH+P  + PGI    G   +     SPE Y GK ++++G GNS  ++A  L  V   + L++    R +W  H V
Sbjct:    2 VKKQIAVIGAGISGLGAIKCCLDEDLEPTCFERNDDIGGLWK-FQKNASEKMPSIYRSVTINTSKEMMCFSDFP--IPDHFPNYMHN---------SKLMDYFRMYAKRFSLLDYIRFKTTVRSVRKRPD--FHIHGQWDVVVETDGKQESLVFDGVLVCSGHHTDPHLPLKSFPGIEKFEGCYFHSREYKSPEDYVGKRIIVVGIGNSGVDIAVELGRVAKQVFLSTR---RGSWILHRV 225          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q8IWF2|FXRD2_HUMAN (FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FOXRED2 PE=1 SV=1)

HSP 1 Score: 528.48 bits (1360), Expect = 1.663e-179
Identity = 266/581 (45.78%), Postives = 366/581 (62.99%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHS-DIIKFEKCNKTGKINIFL------RSIDGKTFIKYDK-------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNER----KKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP+GLQM Y++++  R+Y +FER    G+FF  +PRH  LISINKR+TG++N EFN+RHDWNSLL+ D   LFR++S+ +FP+  D+ +Y   +     + +Q+NTTI+ +  D D++      F + DQ G  ++C +L VATGLS P+  + PG  Y  GYES+++ PE + G++VLILG+GNSAFE A ++ GVTN I + S S VRL+WATHYVGD+RAINN +LDTYQLKSLDG+LE +L    I+K  K         FL      +S D  T  + D         YD VIRC GW F++ IF +     S+R+N      KK+P I+A Y S     L+  G  +HS+D+RKSAGGFIHGFRYT R +HR++E+RHH   WP     I  + +  VRR+NE S  YQMFG L D+ ++ E+  ++ ++EE+PI  LA  E  TG + +  + V   EYGR+FS    + F D+R  G    A  SNFLHPVIY Y  LPTE+++R R     LP+P  +HH+ EDF T+W      I P +RF+EN L  DL S+ AE+C    LT+
Sbjct:   33 YCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNK-----SLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTR 608          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q3USW5|FXRD2_MOUSE (FAD-dependent oxidoreductase domain-containing protein 2 OS=Mus musculus OX=10090 GN=Foxred2 PE=2 SV=1)

HSP 1 Score: 520.39 bits (1339), Expect = 1.451e-176
Identity = 259/579 (44.73%), Postives = 368/579 (63.56%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLR---------SIDGKTFIKYDK-------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC++GAGP+GLQM  ++ +  R+Y +FER S+ G+FF  +PRH  LISINKR TG++N EFN+RHDWNSLL+DD   LFR++S+ +FP+  D+ +Y   + +   +++ +NT I+ +  D D +      F + DQ G  Y+C +L+VATGL+ P + + PG  Y  GYES+++ PE + G++VLILG GNSAFE A ++ GVTN + + S S VRL+WATHYVGDVRAINN +LDTYQLKSLDG+LE +L  + +   K +K GK ++ L+         S D     + D        +YD VIRC GW F++ IF++ ++  S      KK+P I+A Y S     L+  G  +HS+D+RKSAGGFIHGFRYT R +HR++E+RHHG  WP     I  + +  +RR+NE S  YQMF  L DI ++ E+  ++ ++EE+P+  LA  E+ TG   R  + V   EYG++FS    + F  +R    +  A +SNFLHPVIY Y  LPTE+ +R R  +  LP+P  +HH+ EDF T+W      I P +RF+EN L  DL S+ AE+C    LT+
Sbjct:   24 YCVLGAGPAGLQMAAFLHRAGRDYEVFERESAPGSFFTRYPRHRKLISINKRHTGKANAEFNLRHDWNSLLSDDPHLLFRHYSQAYFPDASDMVRYLGDFARRLGLHVLYNTNITHVTLDKDPQAWNGHYFILTDQKGQVYQCSVLLVATGLAVPKLVDFPGSEYVEGYESVSVDPEDFVGQNVLILGHGNSAFETAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSLDGLLESDL--EYLALVKDSK-GKFHVTLKFLLENNSSQSADSIPLPEDDNDNFAMRVAYDRVIRCLGWTFDFSIFDQ-SLRLSSGTEFSKKYPLIKASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHGIPWPSTEYPITQLTSSIIRRVNEASGLYQMFSVLADIILLKENATAFEYLEEFPMQMLAQLEMLTGRTARHGLFVINMEYGKNFSGPEKDVFYYDRSVAHIEDAWMSNFLHPVIYYYRHLPTEQDMRFRPAQWPLPRPTAIHHIVEDFLTDWTAPVGHILPLRRFLENCLDTDLRSFYAESCFLFTLTR 598          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|B0UXS1|FXRD2_DANRE (FAD-dependent oxidoreductase domain-containing protein 2 OS=Danio rerio OX=7955 GN=foxred2 PE=2 SV=1)

HSP 1 Score: 443.736 bits (1140), Expect = 1.875e-146
Identity = 238/597 (39.87%), Postives = 340/597 (56.95%), Query Frame = 1
Query:  145 KYCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQ---DSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKI-----------------------------NIFLRSIDGKTFIKYD-------KSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSK-VLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLT 1815
            +YC++GAGP+GLQMGY++ + QR+Y+I ER +  G+FF  +PRH  LISINK +TG  N+EFN+RHDWNSLL+D    LF+  S++ +P+ DD   Y + + K   + +++ T + +I+    +  + + + DQNG +Y+C +L+V+TGL  P   +  G     GYES+   PE ++ + VLILGKGNSAFE A S+ G  + I L S S VRLAW THYVGD+RA+NN +LDTYQLKSLDG++E  L  DI    +    GK                              +  + ++ G+    Y        + YD VIRC G++FN+ IF+ +  P       R + P + A Y      N++  G   HS D+R SAGGFIHGFRYT R +H+I+E R+H   WP     I+ + +  +RR+NE S TYQMFG LGDI ++      Y  +EE+P+  L      +G  +    +LV V +YG + +   G      R +   T A  SNFLHPV+Y Y  LPT++ +R R     LP+P  +HH+ EDF T W        P +RF+E+ LK DL ++ AE+C  L LT
Sbjct:   35 EYCVLGAGPAGLQMGYFLSRSQRDYIILERNAGPGSFFNIYPRHRKLISINKIYTGRRNKEFNLRHDWNSLLSDRPDLLFQRISRKLYPSADDFPHYLSLFEKELGLKVKYGTDVGRIKASDFNGHQGYVLTDQNGVNYQCRVLLVSTGLWVPQEVDFRGSDLVEGYESIPTDPEEFKDQAVLILGKGNSAFETAQSILGRASRIHLYSPSPVRLAWQTHYVGDLRAVNNELLDTYQLKSLDGLVEGRL-EDIAIVRRAKDRGKRRAAKKRNSTSTKRNEPLYLTLTELLDDQNDTNISNVTGQNLPGYHTDNFSLRQPYDRVIRCLGFRFNFSIFDGSARPPQ-SSGARGRLPGVTAWYEGRGTPNMFVLGIAAHSRDYRMSAGGFIHGFRYTVRAVHKILEQRYHNIAWPTTNIPISQLQSWILRRVNEASGTYQMFGVLGDIILLQGSHCEY--LEEFPLQALPQLSALSGRSISDHGLLVLVMQYGLNHTDTLG----PGRAESEWTKAWKSNFLHPVLYYYKTLPTDKDMRQRPVGWPLPRPEAVHHMVEDFLTEWDQPISHSQPLRRFLEHCLKTDLRAFYAESCFLLSLT 623          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q9LFM5|YUC4_ARATH (Probable indole-3-pyruvate monooxygenase YUCCA4 OS=Arabidopsis thaliana OX=3702 GN=YUC4 PE=1 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.827e-11
Identity = 73/282 (25.89%), Postives = 118/282 (41.84%), Query Frame = 1
Query:  154 IIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQ-QDSDKRFSMEDQNGSHYKCHILVVATGLSS-PHIPNIPGIHYTIG---YESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHS-----DIIKFEKCNKTGKINIFLRSIDGKTFI 969
            I+GAGPSGL +   +  +    VI ER     + +Q        + + K F       F                  +NF K  +P+K     Y   Y   + I   FN T+ K +  D+   ++++ Q+G  Y    LVVATG ++ P  PNIPG+    G   + S   S   +  + VL++G GNS  EV+  L        +   + V +     +      I   +L  + LK +D  L +  +S     D++   +  KTG I   L+++ GKT +
Sbjct:   19 IVGAGPSGLAVAACLSNRGVPSVILERTDCLASLWQKRTYDRLKLHLPKHFCELPLMPFP-----------------KNFPK--YPSKQLFISYVESYAARFNIKPVFNQTVEKAEFDDASGLWNVKTQDGV-YTSTWLVVATGENAEPVFPNIPGLKKFTGPVVHTSAYKSGSAFANRKVLVVGCGNSGMEVSLDLCRYNALPHMVVRNSVHVLPRDFFGLSTFGIAMTLLKWFPLKLVDKFLLLLANSTLGNTDLLGLRR-PKTGPIE--LKNVTGKTPV 277          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|O23024|YUC3_ARATH (Probable indole-3-pyruvate monooxygenase YUCCA3 OS=Arabidopsis thaliana OX=3702 GN=YUC3 PE=2 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 4.212e-11
Identity = 58/207 (28.02%), Postives = 93/207 (44.93%), Query Frame = 1
Query:  154 IIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSD------KRFSMEDQNGS---HYKCHILVVATGLSSPH-IPNIPGIHYTIGYESMNI----SPEYYEGKDVLILGKGNSAFEVANSLY 732
            I+GAGPSGL +   ++++   ++I ER +   + +QN       + + K+F    N  F           D+F           +P K    +Y   Y  ++ IN +FN T+   + D        K  S   Q GS    Y C  +VVATG ++   +P+  G+    G + ++     S   Y+GK VL++G GNS  EV+  LY
Sbjct:   39 IVGAGPSGLAVAAGLKREGVPFIILERANCIASLWQNRTYDRLKLHLPKQFCQLPNYPF----------PDEFPE---------YPTKFQFIQYLESYAANFDINPKFNETVQSAKYDETFGLWRVKTISNMGQLGSCEFEYICRWIVVATGENAEKVVPDFEGLE-DFGGDVLHAGDYKSGGRYQGKKVLVVGCGNSGMEVSLDLY 225          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. TrEMBL
Match: A0A2C9K1U2 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106078228 PE=4 SV=1)

HSP 1 Score: 552.747 bits (1423), Expect = 0.000e+0
Identity = 265/568 (46.65%), Postives = 389/568 (68.49%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIK-YDKS----YDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YCI+G GPSGLQ+GY+M+   R+Y++FER + +G+FFQ +PRH  LIS+NKR TG+ N+EFN+RHDWNSLL+ D   L   +S+E FPN D L KY + Y K   IN++FN  I  I+ + ++       F+M+DQ G  Y C  L++ATG+S+P+IPN  GI+ T+GYESM+++PE YEGK VLILG+GNSAFE+A+S+YG  N I L   S +RLAWATHYVGD+RA+NN +LDTYQLKSLDG+ E+ + +++   +K  K     I+L  +D +     ++++    YDVVIR  G+ F+   F   ++  ++   + KK+PAI  +Y SV++  L++AG  +HS+DFRKS+GGFIHGFRYT+R LHR++E+R+ G  WP++   +  ++N+ ++R+NE S TYQMF  LGD+ I+SED+ES   +EE+PI  L +    TG    S  +V V EYG +FS    + F  +R  G    A LSNFLHPVIY Y +LPTEE ++++ + + LP+P+++HH+ EDF+T+W+  +  I P +RF E +L  DL ++  ++C  + +T+
Sbjct:   26 YCIVGGGPSGLQLGYFMKTASRDYIVFERSNISGSFFQQYPRHRKLISLNKRNTGKVNKEFNLRHDWNSLLSHDPDLLVTKYSREIFPNADVLVKYLDDYQKKLDINVKFNANIYNIRTEKNQSSPDGQVFTMQDQTGQSYVCRTLIMATGVSTPNIPNGDGINLTVGYESMSLNPEDYEGKSVLILGRGNSAFEIADSIYGYANFIHLLGRSRIRLAWATHYVGDLRAVNNAVLDTYQLKSLDGLFEMHVDTEMKLIQKGGK-----IYLPEVDDELITAPFERTILEPYDVVIRALGFIFDTSPFYNKSL--TLGAGKLKKYPAITHNYESVDYTGLFYAGTASHSLDFRKSSGGFIHGFRYTARALHRLMEWRYEGIPWPYIDLRLPQLMNYVIKRMNEVSGTYQMFQVLGDVLIVSEDKESIRVIEEFPIHLLHELPQRTG-HNGSAYIVIVLEYGHNFSGPNNDVFRLDRAVGGAIYASLSNFLHPVIYYYSQLPTEESMQSKSKNETLPRPDYIHHIVEDFYTSWQKSQTHILPLRRFFEKVLSVDLRTFYTKSCFLVSMTK 585          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. TrEMBL
Match: A0A0P4VX81 (Uncharacterized protein OS=Scylla olivacea OX=85551 PE=4 SV=1)

HSP 1 Score: 546.584 bits (1407), Expect = 0.000e+0
Identity = 265/582 (45.53%), Postives = 374/582 (64.26%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDK------RFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINI-FLRSIDGKTFIKYDK-------------------SYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLT 1815
            YC+IGAGP+GLQMGY++    R+Y+IFER + +G+FF  +PRH  LISINKR+TG++N EFNMRHDWNSLL+ D S LF++FS EFFP  D + +Y   +     + +++NT +  +Q+  D        FS  DQ+G  Y C  +V+ATG+S P  PN PG HYT+GYE + + P +YEGK+VLILG+GN+AFE A+++YG TN + + S S  RL+W THYVGD+RA+NN +LDTYQLKSLDG++E  +   ++  EK N  G+I + F    + K  ++ +K                    YDVV+RC G+KF++ IF  +TMP +    ++ K+PA++  Y +     LYFAG  THS+D+R+SAGGFIHGFRYT R LHR++E+R  G++WP    AI  ++N  V+R+NE S  YQMFG L D+ ++ + +  +  +EE+P+  LA  E  TG +   +V+V + EYG DFS    + F  +R  G    AH SNFLHPV+Y Y  +PTE  +  +  K  LPKP  +HHV EDF T W  ++  I P +RF+E ++  DL  + A TCL+L LT
Sbjct:   90 YCVIGAGPAGLQMGYFLHTAGRDYLIFERANHSGSFFSEYPRHRRLISINKRYTGKTNAEFNMRHDWNSLLSHDPSLLFKHFSSEFFPEADAMVRYLGEFAGRLGLRVKYNTVVQDLQRHHDSTASPKGHFSFRDQHGRRYSCRTVVMATGMSVPSKPNFPGAHYTLGYEKLPLDPAFYEGKNVLILGRGNAAFETADAIYGSTNMVHMVSRSRARLSWNTHYVGDLRAVNNGLLDTYQLKSLDGLVEASVEDMVL--EKQN--GQIYVQFPWDNESKNHLQANKGKERKMKAENPFDNFCLREGYDVVLRCLGFKFDFSIFSNSTMPDT--SAKKSKYPAVKHTYEAQSVPGLYFAGTATHSLDYRRSAGGFIHGFRYTVRALHRLLEWRLEGRRWPVTSYAIRDLLNVLVKRMNEASGPYQMFGELADVVLLRDGKTRFELLEEFPVHLLAQLEDLTGREA-GEVVVMMMEYGPDFSGPEKDTFRMDRSTGDPLEAHRSNFLHPVLYYYKSVPTEADMMMKWGKTSLPKPERIHHVIEDFLTVWTSQQSHILPLRRFLEYVMGNDLRHHYAHTCLSLALT 664          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. TrEMBL
Match: A0A1S3JL29 (FAD-dependent oxidoreductase domain-containing protein 2-like OS=Lingula unguis OX=7574 GN=LOC106174226 PE=4 SV=1)

HSP 1 Score: 544.273 bits (1401), Expect = 0.000e+0
Identity = 266/566 (47.00%), Postives = 372/566 (65.72%), Query Frame = 1
Query:  145 KYCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDK-RFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIEL-HSDIIKFEKCNKTGKINIFLRS--IDGKTFIKYD--KSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS 1824
            +YCI+GAGP GLQ+GY+++   R+YVIFER + +G+FF  +PRH  LISINKR TG++N+EFN+RHDWNSL++ D S   R++SK  FP+++ L KY   Y +   IN+Q+N  +  I++ SD   FSMEDQ G+ Y C  +++ATGL   H+P   G+ YTIGY  ++I+P+ +EGK VLI+G+GNSAFEVA+ +YG TN I + + S VRL+WATHYVGD+RA+NN +LDTYQLKSLD +LE  +  + ++K     K GKI +   +  +D   F  +     YDVVIRCTGWKF+ E+F  +T P   +   RKKFP     Y S     L+FAG  +HS+DFRKSAGGFIHGFRYT+R L+  +E+R+HG +WP +   I  +++  ++RINE S  YQMF  LGD+ ++  +   + ++EE+PI+ L  F   TG +   K++V V EYG +FS  G + F   R  G  + AH SNFLHPV Y Y+ LPTE+ ++ +G K  LPKP  LHH+ EDF T W      I P ++F+E  +  D+  Y A +C  L +T  +
Sbjct:   30 EYCIVGAGPGGLQLGYFLKTSNRDYVIFERNNVSGSFFTKYPRHDMLISINKRNTGKTNKEFNLRHDWNSLISHDESLQVRHYSKVMFPHREVLVKYLGDYQRKLGINVQYNVDVHNIRKRSDTGLFSMEDQRGNAYSCKNVIIATGLQKEHVPQFRGVEYTIGYNDVSINPDDFEGKSVLIIGRGNSAFEVADRIYGATNVIHMIARSRVRLSWATHYVGDLRAVNNGLLDTYQLKSLDAVLEAPIEEAALVK----TKQGKIKLVFSAGDMDENLFDNFAMRDDYDVVIRCTGWKFDDEVFHNSTKPERGQ-GRRKKFPKTLPTYESTNIPGLFFAGTNSHSVDFRKSAGGFIHGFRYTARTLYNYLEHRNHGVEWPSIKAPITELLDRILKRINEASGIYQMFQVLGDVILLKNNGREFEYLEEFPIMSLPKFHEITG-KTAEKIIVVVLEYGANFSGPGNDVFRLNRATGEPSDAHQSNFLHPVFYYYETLPTEKDMKKKGSK-TLPKPVHLHHIVEDFLTTWDAPLSHILPLRQFLERCIGTDMRKYFASSCFTLAMTHQT 588          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. TrEMBL
Match: A0A091VZN5 (FAD-dependent oxidoreductase domain-containing protein 2 (Fragment) OS=Nipponia nippon OX=128390 GN=Y956_01168 PE=4 SV=1)

HSP 1 Score: 542.347 bits (1396), Expect = 0.000e+0
Identity = 271/583 (46.48%), Postives = 373/583 (63.98%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHS-DIIKFEKCNKTGKINIFLR----------SIDGKTFIKYD-------KSYDVVIRCTGWKFNWEIFERN--TMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQ 1818
            YC+IGAGPSGLQ  Y+++Q  R+YV+FER  + G+FF  +PRH  LISINKR+TG+SN EFN+RHDWNSLL+ D   LF+ +S++FFPN D + +Y   +    K+ +Q+NT I  +  + D +      F + DQ+  +YKC  L+VATG+  P++ N PG  Y  GYE+++I+PE + G+ VLILG+GNSAFE A ++ GVTN I + S S VRL+WATHYVGD+RAINN +LDTYQLKSLDG+LE +L    I+K    +K GK++I LR           ID  T  + +         YD VIRC GWKF++ I+ R+   MPG      +KK+P I+  Y S     L+  G  +HS+DFRKSAGGFIHGFRYT+R +HR++E RHHG  WP  V  I  + N  ++R+NE S  YQMF  L DI ++ E+  ++ ++EEYP+  LA+ E+ TG +  + + V + EYGR+FS    + F   R  G    A  SNFLHPVIY Y +LPTE ++R R     LP+P+ +HH+ EDF T+W      I P +RF+EN L  DL ++ AE+C     T+
Sbjct:   23 YCVIGAGPSGLQAAYFLQQASRDYVVFERSHAPGSFFALYPRHRKLISINKRYTGKSNGEFNLRHDWNSLLSHDRQLLFQRYSRDFFPNADAMVRYLEDFASLLKLRVQYNTAIVHVTLERDGQAWNGHYFLLTDQDRQNYKCSSLLVATGMWVPNVVNFPGSEYVEGYETVSINPEDFAGQTVLILGRGNSAFETAENILGVTNFIHMVSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLEGDLEDLAIVK----DKKGKLHITLRFYLDNRNTSAGIDSITLPQDELDNFATRAPYDRVIRCLGWKFDFSIYNRSLRMMPGK---GNKKKYPQIKPSYESRGTRGLFVLGTASHSVDFRKSAGGFIHGFRYTTRAVHRLLENRHHGVPWPSTVYPITQLTNSIIKRVNEASGLYQMFSVLADIILLRENATAFEYLEEYPVGVLAELEMQTGRKAPNGLFVIIMEYGRNFSGADKDVFYYNRAVGEAQHAWQSNFLHPVIYYYKRLPTEHEMRLRPPDWPLPRPDAVHHIVEDFLTDWTAPNAHILPLRRFLENCLSTDLRNFFAESCFLFAFTR 598          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. TrEMBL
Match: A0A210R4C7 (FAD-dependent oxidoreductase domain-containing protein 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT06459 PE=4 SV=1)

HSP 1 Score: 542.347 bits (1396), Expect = 0.000e+0
Identity = 264/573 (46.07%), Postives = 377/573 (65.79%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR------FSMEDQNGSHYKCHILVVATGLSSPHIPN-IPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIKYD-----KSYDVVIRCTGWKFNWEIFERNT--MPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS 1824
            YCI+GAGP GLQM Y+MEQ  R+Y++FER ++ G+F+  +PRH  LISINKR TG+SN+EFN+RHDWNSL++ D S LF+++SKE FP+ D L +Y   Y K   +N+QFN+ +  I++ ++        ++MED  G+ Y C  ++VATG++ P+IP  +PG+ Y  GYES++I+P+ +EG+ VLILG+GN+AFEVA+S+YG TN I +   S VRLAWATHYVGD+RA+NN +LDTYQLKSLDG+LE  L  D +K  K  +  K  +  +  +  +    D     + YD ++RC G+ F+  IF   +  + G  R    KKFP I  DY S     +Y  G  +HS+DFRKSAGGFIHG+RYT+R LH ++E+R+H   WP     I  ++ H ++RINE S TYQMFG LGDI I+ ++   YT++EEYPI  +   E + G    ++++  V +YG +FS  G + F  +R  G  + AH SNFLHPV+Y Y+ LPT+ Q+    + +ILP+P  +HH+ EDF T W      I P +R+IEN+L  D+ ++ +E CL + LTQ +
Sbjct:   31 YCILGAGPGGLQMAYFMEQSSRDYIVFERENTTGSFYTVYPRHRKLISINKRHTGKSNKEFNLRHDWNSLISHDESLLFKHYSKEMFPHADALVQYLQDYHKKLGLNVQFNSNMQNIRRVANDSSAGGHIYTMEDDKGNPYTCSKVIVATGIAEPNIPKEVPGMEYADGYESVSINPDDFEGQSVLILGRGNAAFEVADSIYGSTNVIHMVGRSRVRLAWATHYVGDLRAVNNGLLDTYQLKSLDGVLEAGL--DEVKLVK--QGSKFVLQFKDEEEDSMFPLDNFALREPYDRIVRCLGFAFDSSIFNETSKMILGKGRT---KKFPKIDYDYQSTNNPGMYVVGVASHSLDFRKSAGGFIHGYRYTARALHHLMEWRYHQVPWPSTTGPITQLLTHIIKRINEASGTYQMFGILGDIIILKDNGREYTYLEEYPINLIHRLEEDAG-HPTTRIIAVVLQYGANFSGPGNDIFRVDRATGEPSEAHTSNFLHPVLYYYETLPTKSQMLRIAKDEILPRPKLMHHIVEDFLTVWDGPLSHILPLRRYIENVLSSDMRNFFSEDCLEMALTQKT 595          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Cavefish
Match: foxred2 (FAD dependent oxidoreductase domain containing 2 [Source:NCBI gene;Acc:103021769])

HSP 1 Score: 435.261 bits (1118), Expect = 7.239e-144
Identity = 238/603 (39.47%), Postives = 340/603 (56.38%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQ---DSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELH-------------------------------------SDIIKFEKCNKTGKINIFLRSIDG--KTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRV----NERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSK-VLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLT 1815
            YCI+GAGP+GLQMGY++ +  R+Y+I ER +  G+FFQ +PRH  LISINK +TG  N+EFN+RHDWNSLL+D    LF+  S++ +P+ D    Y + + +   + +++ T I K++       K + + DQ+G+ YKC +L V TGL  P   +  G     GYES+   PE Y+ + VLILGKGNSAFE A S+ G  + I + S S VRLAW THYVGD+RA+NN +LDTYQLKSLDG++E  L                                      S+++     NK+G  NI   ++ G         + YD VIRC G++FN+ I++     GS R+      R + PA+ A Y      NL+  G   HS D+R SAGGFIHGFRYT R +H+++E R+H   WP    + + +++  ++R+NE S  YQMFG LGD+ ++      Y  +EE+P+  +      +G  V    +LV V +YG + +   G      R +   T A  SNFLHPVIY Y KLPTE+ ++ R     LP+P+ +HH+ EDF T W        P + F+E+ L+ DL ++ AE+C  L LT
Sbjct:   46 YCILGAGPAGLQMGYFLSRSHRDYIILERNTGPGSFFQRYPRHRKLISINKIYTGRQNKEFNLRHDWNSLLSDQPDLLFQRVSEDLYPHADAYPLYLSMFERELGLRVKYATDIGKVRAADFTGSKGYILTDQHGADYKCRVLFVCTGLWVPQQVDFVGSDLVEGYESIPTDPEDYKNQAVLILGKGNSAFETAQSILGRASRIHMYSPSPVRLAWKTHYVGDLRAVNNELLDTYQLKSLDGLVEGGLEDIAIVRRGQDGGKSRRTGGKKRTVKSTERKEQFYLTLSELLDNRNSNKSG--NITAENLPGYHDDNFSLRQPYDRVIRCLGFRFNFSIYD-----GSARLLHSSCARGRLPALTAWYEGRGTPNLFVLGTAAHSRDYRMSAGGFIHGFRYTVRAVHKVLEQRYHNIAWPATRLSTSQLLSWILKRVNEASGPYQMFGVLGDVILLQGSHCEY--LEEFPVQAMPQLSTLSGRLVSEHGLLVLVMQYGLNRTDTLG----PGRAESEWTKAWKSNFLHPVIYYYRKLPTEKDMKQRPVGWPLPRPDAVHHMVEDFLTEWDQPISHSQPLRHFLEHCLQTDLRAFYAESCFRLSLT 635          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000519.1 (pep scaffold:Pmarinus_7.0:GL494029:1149:4459:1 gene:ENSPMAG00000000468.1 transcript:ENSPMAT00000000519.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 263.077 bits (671), Expect = 7.104e-84
Identity = 114/235 (48.51%), Postives = 174/235 (74.04%), Query Frame = 1
Query:  130 NAIEWKYCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDK------RFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRA 816
            ++I   +C++GAGPSGLQMGYY+EQ +R+YVI ER  + G FF  +PRH  LISINKR TG+ N+EFN+RHDWNSLL+ D + LFR++S++FFP+ DD+ +Y + Y K +++N+++NT +++I+  +D       RF + DQ+G+ ++C +L+VATG+  P +P   G     GYE+++++P  +EG+ VLILG+GNSAFE A+++ G TN + +   S +RL+WATHYVGD+R+
Sbjct:   28 SSIAKDFCVVGAGPSGLQMGYYLEQSRRDYVILERSGAPGHFFAVYPRHRKLISINKRHTGKRNKEFNLRHDWNSLLSHDETMLFRHYSRDFFPHADDMVRYLSDYAKRFRLNVRYNTNVTEIRATADSSAWNGHRFVLGDQSGNEWRCQVLLVATGMWLPRVPRFIGSELVEGYENVSVNPSDFEGQSVLILGRGNSAFETADNIMGSTNLVHMLGRSHLRLSWATHYVGDLRS 262          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO26107 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DVA2])

HSP 1 Score: 77.0258 bits (188), Expect = 3.669e-17
Identity = 45/104 (43.27%), Postives = 61/104 (58.65%), Query Frame = 1
Query: 1396 FVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDI-LPKPNFLHHVKEDFHTN 1704
            + EEYPI  L  F+  TG +    ++V   EYG +FS  G + F  +R  G    AH+SNFLHPV Y Y K P +  +    EKDI LP+P+ +HH+ EDF T+
Sbjct:    7 YFEEYPIKTLNAFKKITGYKP-GPMVVLNMEYGPNFSGAGKDIFRPDRAHGEAREAHMSNFLHPVFYFYKKHPNKMNV----EKDIRLPRPDRIHHIVEDFLTS 105          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Medaka
Match: foxred2 (FAD dependent oxidoreductase domain containing 2 [Source:NCBI gene;Acc:101156499])

HSP 1 Score: 452.595 bits (1163), Expect = 8.252e-151
Identity = 239/593 (40.30%), Postives = 345/593 (58.18%), Query Frame = 1
Query:  148 YCIIGAGPSGLQMGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKI---QQDSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEK--------CNKTGKINIFLRSIDGKTFIKYDKS----------------------YDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQV-RSKVLVFVFEYGR---DFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLT 1815
            YC++GAGP+GLQMGY++ + +R+Y+I ER S  G+FF+ +PRH  LISINK  TG  N+EFN+RHDWNSLL+D    LF+  S EF+P  D L  Y + + K   + +Q+   + +I   +  +++ + + DQ G  Y C +L+VATGL  P +    G     GYES++ +PE Y+ + VLILGKGNSAFE A S+ G  + + + S+S VRLAW THYVGD+RA+NN ++DTYQLKSLDG++E  L   +I   K          K  K   F   +       +DK+                      YD VIRC G++FN+ IF+ +  P +   N + + P I A Y   +   L+  G  +HS D+R SAGGFIHGFRYT+R +HR++E+R+HG  WP +  +   +++  ++RI+E S  YQMF  +GD+ ++   R  Y  VEE+ +  L  F   +G QV R   +V V +YG+   D+   G       R +   T A  SNFLHPV+Y YD+LPTEE++  R     LP+P  +HH+ EDF T W      I P + F+E+ ++ DL ++ AE+C    LT
Sbjct:   34 YCVLGAGPAGLQMGYFLSKAKRDYIILERNSGPGSFFKKYPRHRKLISINKIHTGRRNREFNLRHDWNSLLSDRPDLLFKRVSSEFYPPADKLPLYLSMFEKELGLKVQYRVDVGRIRAVESAAERSYILTDQQGGDYTCRVLLVATGLWVPQVVEFVGSDLVEGYESISTNPEDYKDQAVLILGKGNSAFETAQSIIGTASRVHMLSSSPVRLAWQTHYVGDLRAVNNELIDTYQLKSLDGLVEARLEKIVIAERKDQSKRAPGGKKKAKRRQFYLMLKKYPQNSHDKNSSGVTQEELSGYIIDNFPMRKPYDRVIRCLGFRFNFSIFDSSASPPNSE-NAKGRLPGITAWYEGKDSPGLFVLGTASHSRDYRASAGGFIHGFRYTARAVHRVLEHRYHGNAWPSINLSTTQLLSWILKRISEASGPYQMFEVVGDVILLQGPRCEY--VEEFLLQALPQFSSLSGHQVSRHGFIVLVMQYGKKKIDYLGRG-------RAETDWTKAWKSNFLHPVLYYYDRLPTEEEMSMRPHGWPLPRPRAIHHMVEDFLTEWDGPLSHIQPLRHFLEHCVQTDLRAFYAESCFRAALT 616          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000022422.1 (SMESG000022422.1)

HSP 1 Score: 1131.7 bits (2926), Expect = 0.000e+0
Identity = 543/547 (99.27%), Postives = 545/547 (99.63%), Query Frame = 1
Query:  184 MGYYMEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS 1824
            MGYYMEQKQRNYVIFERGSSAGTFF+NFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNT ISKIQQDSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISED ESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKD+LPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS
Sbjct:    1 MGYYMEQKQRNYVIFERGSSAGTFFKNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTAISKIQQDSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDLESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDVLPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS 547          
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000022422.1 (SMESG000022422.1)

HSP 1 Score: 1121.69 bits (2900), Expect = 0.000e+0
Identity = 539/543 (99.26%), Postives = 541/543 (99.63%), Query Frame = 1
Query:  196 MEQKQRNYVIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS 1824
            MEQKQRNYVIFERGSSAGTFF+NFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNT ISKIQQDSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISED ESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKD+LPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS
Sbjct:    1 MEQKQRNYVIFERGSSAGTFFKNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDDFSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTAISKIQQDSDKRFSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYEGKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAINNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFIKYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVEFDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHLVKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDLESYTFVEEYPILRLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHLSNFLHPVIYAYDKLPTEEQIRNRGEKDVLPKPNFLHHVKEDFHTNWRVREDSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTS 543          
The following BLAST results are available for this feature:
BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
FOXRED23.462e-18045.78FAD dependent oxidoreductase domain containing 2 [... [more]
FOXRED23.462e-18045.78FAD dependent oxidoreductase domain containing 2 [... [more]
FOXRED23.462e-18045.78FAD dependent oxidoreductase domain containing 2 [... [more]
FOXRED23.790e-1855.56FAD dependent oxidoreductase domain containing 2 [... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fmo-44.969e-1024.54Dimethylaniline monooxygenase [N-oxide-forming] [... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
foxred22.484e-14739.87FAD-dependent oxidoreductase domain containing 2 [... [more]
foxred22.484e-14739.87FAD-dependent oxidoreductase domain containing 2 [... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
foxred21.871e-16142.96FAD-dependent oxidoreductase domain containing 2 [... [more]
foxred26.933e-16043.17FAD-dependent oxidoreductase domain containing 2 [... [more]
ywhaq7.603e-825.75tyrosine 3-monooxygenase/tryptophan 5-monooxygenas... [more]
ywhaq8.532e-825.75tyrosine 3-monooxygenase/tryptophan 5-monooxygenas... [more]
ywhaq9.306e-825.75tyrosine 3-monooxygenase/tryptophan 5-monooxygenas... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Foxred22.074e-17744.73FAD-dependent oxidoreductase domain containing 2 [... [more]
Foxred22.074e-17744.73FAD-dependent oxidoreductase domain containing 2 [... [more]
Fmo94.702e-624.90flavin containing monooxygenase 9 [Source:MGI Symb... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IWF2|FXRD2_HUMAN1.663e-17945.78FAD-dependent oxidoreductase domain-containing pro... [more]
sp|Q3USW5|FXRD2_MOUSE1.451e-17644.73FAD-dependent oxidoreductase domain-containing pro... [more]
sp|B0UXS1|FXRD2_DANRE1.875e-14639.87FAD-dependent oxidoreductase domain-containing pro... [more]
sp|Q9LFM5|YUC4_ARATH1.827e-1125.89Probable indole-3-pyruvate monooxygenase YUCCA4 OS... [more]
sp|O23024|YUC3_ARATH4.212e-1128.02Probable indole-3-pyruvate monooxygenase YUCCA3 OS... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2C9K1U20.000e+046.65Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A0P4VX810.000e+045.53Uncharacterized protein OS=Scylla olivacea OX=8555... [more]
A0A1S3JL290.000e+047.00FAD-dependent oxidoreductase domain-containing pro... [more]
A0A091VZN50.000e+046.48FAD-dependent oxidoreductase domain-containing pro... [more]
A0A210R4C70.000e+046.07FAD-dependent oxidoreductase domain-containing pro... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
foxred27.239e-14439.47FAD dependent oxidoreductase domain containing 2 [... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000000519.17.104e-8448.51pep scaffold:Pmarinus_7.0:GL494029:1149:4459:1 gen... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO261073.669e-1743.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
foxred28.252e-15140.30FAD dependent oxidoreductase domain containing 2 [... [more]
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BLAST of FAD-dependent oxidoreductase domain-containing protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000022422.10.000e+099.27SMESG000022422.1[more]
SMESG000022422.10.000e+099.26SMESG000022422.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031126 ID=SMED30031126|Name=FAD-dependent oxidoreductase domain-containing protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1911bp
CTAGGCAGCTCAATTTGCGAGCTCATATTTGTAACGTGACCGGTATTGCA
AAGGGGACGGAATATAAAAATGAATATAGAGATTTTTATAATAATTTTAT
TAGTAAACATTTCTCTGAATATACATGGAAATGCAATTGAATGGAAGTAT
TGTATCATTGGAGCTGGGCCTTCAGGACTTCAGATGGGATATTATATGGA
ACAAAAGCAAAGAAATTACGTGATATTCGAAAGAGGTTCTAGTGCAGGAA
CATTTTTTCAAAATTTTCCTCGCCATGGAACATTGATAAGCATTAATAAA
AGATTTACTGGAGAAAGTAATCAAGAGTTTAATATGCGCCATGATTGGAA
CAGTCTTTTAACCGATGACTTTTCAACTCTTTTCAGAAATTTTAGTAAAG
AATTTTTTCCCAATAAAGATGATCTTTTTAAATATTTCAATTATTATGGA
AAACATTGGAAAATTAATATTCAATTCAACACCACTATTAGCAAAATTCA
ACAAGACTCAGATAAAAGATTTTCAATGGAAGATCAAAACGGTAGCCACT
ACAAATGTCACATTTTAGTAGTTGCTACCGGATTGTCTTCCCCTCACATT
CCAAATATTCCCGGTATTCATTATACAATTGGATATGAAAGTATGAACAT
ATCCCCTGAATATTATGAAGGAAAGGATGTTTTGATATTAGGGAAAGGTA
ATTCGGCTTTCGAAGTAGCTAATTCTTTGTATGGAGTTACTAATACAATA
ACTCTTGCCAGTAATTCAGAGGTTAGATTAGCATGGGCTACACACTATGT
TGGAGATGTGAGGGCAATTAATAACAACATCTTGGATACATACCAGCTGA
AGTCTTTGGATGGGATTTTGGAAATTGAACTCCATTCTGATATTATTAAA
TTCGAAAAGTGCAATAAAACAGGAAAGATTAATATTTTCCTCAGATCAAT
TGATGGTAAAACTTTTATCAAATACGACAAAAGCTACGACGTTGTCATTC
GTTGCACTGGTTGGAAATTCAATTGGGAAATCTTTGAAAGAAATACAATG
CCTGGATCCGTGAGAGTGAATGAGCGGAAAAAATTCCCAGCAATTCAAGC
CGATTACAATTCAGTCGAATTTGATAACTTATATTTTGCCGGTGCGTTAA
CGCACTCGATTGACTTCAGAAAATCTGCCGGTGGATTTATTCATGGGTTT
AGATATACATCCAGATGTTTGCATCGAATCATTGAGTACCGACATCATGG
TAAAAAATGGCCTCATTTAGTTAAGGCAATAAACTCAATTGTGAACCACT
TTGTTAGGCGAATTAACGAAGGTTCGGCAACTTATCAAATGTTCGGAAAT
TTGGGAGATATTGCAATTATTTCAGAAGATCGAGAGTCGTACACATTTGT
TGAGGAGTATCCTATTCTCCGACTGGCTGACTTTGAATTAAACACGGGTA
TTCAGGTCAGATCTAAAGTTTTGGTATTCGTTTTTGAATACGGTCGAGAT
TTCAGCAAAGTTGGTGGTAATCCTTTTAGTGACGAAAGAATCCAAGGCAC
TGTGACAGGTGCACATTTATCGAATTTCTTGCATCCGGTCATTTATGCAT
ACGACAAATTGCCCACGGAAGAACAAATAAGAAATAGAGGAGAAAAGGAT
ATTTTACCAAAGCCAAATTTTTTACATCATGTTAAGGAAGATTTCCACAC
AAACTGGAGAGTCAGAGAGGATTCTATTTATCCATTTCAGAGGTTTATTG
AAAATATTCTAAAGCAAGATTTATCCTCTTATTCTGCTGAGACTTGTTTG
AATTTAATGTTAACTCAGACATCTATCTCCATCAATTGTAACATTAATAA
TAATATAATTATAGCAAAATAAATTGGTAATTAATTGTACAAAGTTGTTT
TGAACATGAAT
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protein sequence of SMED30031126-orf-1

>SMED30031126-orf-1 ID=SMED30031126-orf-1|Name=SMED30031126-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=601bp
MNIEIFIIILLVNISLNIHGNAIEWKYCIIGAGPSGLQMGYYMEQKQRNY
VIFERGSSAGTFFQNFPRHGTLISINKRFTGESNQEFNMRHDWNSLLTDD
FSTLFRNFSKEFFPNKDDLFKYFNYYGKHWKINIQFNTTISKIQQDSDKR
FSMEDQNGSHYKCHILVVATGLSSPHIPNIPGIHYTIGYESMNISPEYYE
GKDVLILGKGNSAFEVANSLYGVTNTITLASNSEVRLAWATHYVGDVRAI
NNNILDTYQLKSLDGILEIELHSDIIKFEKCNKTGKINIFLRSIDGKTFI
KYDKSYDVVIRCTGWKFNWEIFERNTMPGSVRVNERKKFPAIQADYNSVE
FDNLYFAGALTHSIDFRKSAGGFIHGFRYTSRCLHRIIEYRHHGKKWPHL
VKAINSIVNHFVRRINEGSATYQMFGNLGDIAIISEDRESYTFVEEYPIL
RLADFELNTGIQVRSKVLVFVFEYGRDFSKVGGNPFSDERIQGTVTGAHL
SNFLHPVIYAYDKLPTEEQIRNRGEKDILPKPNFLHHVKEDFHTNWRVRE
DSIYPFQRFIENILKQDLSSYSAETCLNLMLTQTSISINCNINNNIIIAK
*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036188FAD/NAD-bd_sf
IPR023753FAD/NAD-binding_dom
Vocabulary: molecular function
TermDefinition
GO:0016491oxidoreductase activity
GO:0001948glycoprotein binding
GO:0005515protein binding
GO:0050660flavin adenine dinucleotide binding
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0030433ubiquitin-dependent ERAD pathway
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0005788endoplasmic reticulum lumen
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePFAMPF13738Pyr_redox_3coord: 1..320
e-value: 1.5E-36
score: 126.2
NoneNo IPR availablePANTHERPTHR43539FAMILY NOT NAMEDcoord: 1..553
NoneNo IPR availablePANTHERPTHR43539:SF23FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2coord: 1..553
IPR036188FAD/NAD(P)-binding domain superfamilyGENE3DG3DSA:3.50.50.60coord: 137..275
e-value: 4.9E-35
score: 123.1
IPR036188FAD/NAD(P)-binding domain superfamilyGENE3DG3DSA:3.50.50.60coord: 7..365
e-value: 4.9E-35
score: 123.1
IPR036188FAD/NAD(P)-binding domain superfamilySUPERFAMILYSSF51905FAD/NAD(P)-binding domaincoord: 4..205