Peptidase S1 domain-containing protein

Overview
NamePeptidase S1 domain-containing protein
Smed IDSMED30031112
Length (bp)1410
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Peptidase S1 domain-containing protein (SMED30031112) t-SNE clustered cells

Violin plots show distribution of expression levels for Peptidase S1 domain-containing protein (SMED30031112) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Peptidase S1 domain-containing protein (SMED30031112) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Peptidase S1 domain-containing protein (SMED30031112) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30031112

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30031112h1SMcG0005695 Contig2033GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30031112h1SMcG0005695 Contig3685GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30031112h1SMcG0005695 dd_Smed_v4_8746_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
tail regionSMED30031112h1SMcG0005695 dd_Smed_v6_8746_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
gutSMED30031112h1SMcG0005695 dd_Smed_v4_8746_0_1dd_Smed_v4PMID:30962434
Cote et al., 2019
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: CELA1 (chymotrypsin like elastase 1 [Source:HGNC Symbol;Acc:HGNC:3308])

HSP 1 Score: 100.908 bits (250), Expect = 1.831e-23
Identity = 75/286 (26.22%), Postives = 123/286 (43.01%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            ++ GG EA ++ W + +        + Y+ CGGTLI   WV+TAAHC++  +                     F ++ GDHN       E   S+   ++HP +  D     YD+ALL+L   +  +  V    + +      N  + CY  GWG                    + + N ++++    LQ+  LP VD  +CS      +  K   VCAG   ++  C GDSGG L C+ +    +H  G+T+F  + GC +S    ++ +V     WI  +I +
Sbjct:   18 RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKT--------------------FRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILAN-NSPCYITGWG--------------------KTKTNGQLAQ---TLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVH--GVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIAS 257          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: CELA2A (chymotrypsin like elastase 2A [Source:HGNC Symbol;Acc:HGNC:24609])

HSP 1 Score: 95.1301 bits (235), Expect = 1.840e-21
Identity = 79/286 (27.62%), Postives = 120/286 (41.96%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            ++ GG+EA  + W   V      +   Y+ CGG+LI   WVLTAAHC+ +    R                    + +G HN  +     +  S+S  ++H  +  ++  K  D+ALLKL  P+  +  +   C+  +     N    CY  GWG                    R Q N  +     VLQ+  L +VD   CS      +  KT  +CAG   +  +C+GDSGG L C   +  R  ++GI +FG   GC   +   ++ RV     WI  +I N
Sbjct:   28 RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYR--------------------VGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPN-NYPCYVTGWG--------------------RLQTNGAV---PDVLQQGRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNC-QASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVIAN 268          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: CELA2B (chymotrypsin like elastase 2B [Source:HGNC Symbol;Acc:HGNC:29995])

HSP 1 Score: 95.1301 bits (235), Expect = 2.148e-21
Identity = 80/287 (27.87%), Postives = 121/287 (42.16%), Query Frame = 1
Query:  526 NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            +++ GG+EA  + W   V      +   Y+ CGG+LI   WVLTAAHC+ +  I R                    +++G HN  +     +  S+S  ++H  +  D+  K  D+ALLKL  P+  +  +   C+  +     N    CY  GWG                    R Q N  +      L++ +L +VD   CS      +  KT  +CAG   +  TC+GDSGG L C   +  R  ++GI +     GC   Y   I+ RV     WI  +I N
Sbjct:   27 SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYR--------------------VMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTILPN-NYPCYVTGWG--------------------RLQTNGALPDD---LKQGQLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNC-QASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVIAN 268          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: CELA3A (chymotrypsin like elastase 3A [Source:HGNC Symbol;Acc:HGNC:15944])

HSP 1 Score: 90.5077 bits (223), Expect = 1.017e-19
Identity = 79/288 (27.43%), Postives = 119/288 (41.32%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIY--GEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFC-VDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            ++  G++A    W   V     K  + Y+ CGG+LI P WV+TA HC     I R L                + +++G++N  +    E  I  +     +HP +         D+AL+KL         V    +  + D   N T  CY  GWG L    P                           LQ+  LP+VD K CS+ +   +  K   VCAG Y++  C+GDSGG L C  +D   ++H  G+T+F  A GC   +   ++ RV     WI + I +
Sbjct:   28 RVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHC-----ISRDLT---------------YQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKT-PCYITGWGRLYTNGPLPDK-----------------------LQQARLPVVDYKHCSRWNWWGSTVKKTMVCAGGYIRSGCNGDSGGPLNCPTEDGGWQVH--GVTSFVSAFGCNFIWKPTVFTRVSAFIDWIEETIAS 269          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Match: TMPRSS6 (transmembrane serine protease 6 [Source:HGNC Symbol;Acc:HGNC:16517])

HSP 1 Score: 93.5893 bits (231), Expect = 1.345e-19
Identity = 97/335 (28.96%), Postives = 155/335 (46.27%), Query Frame = 1
Query:  391 KCETKYIYEKST--CNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGD--HNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAG--TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMI 1371
            +CE +   +K    C+   +C   + S EE        CG+     +++I GG  + + +W       V       ++CGG LI   WV+TAAHC +            M +T L  +F      +G    N+R  G  E+   +S  ++HP +  D +   YDVALL+LD P+  S  V   C+  +R  F      C+  GWG L R    R++ + L +              S+ LQ+V++ L+   +CS+ +  + +   + +CAG     KD C GDSGG L C    S R  L G+ ++GL  GCG    +G+Y R+  V  WI++++
Sbjct:  528 QCEDRSCVKKPNPQCDGRPDC--RDGSDEEHCD-----CGL--QGPSSRIVGGAVSSEGEWPWQASLQV----RGRHICGGALIADRWVITAAHCFQE---------DSMASTVLWTVF------LGKVWQNSRWPG--EVSFKVSRLLLHPYHEEDSH--DYDVALLQLDHPVVRSAAVRPVCLP-ARSHFFEPGLHCWITGWGAL-REGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVY-RYQVTPRM-LCAGYRKGKKDACQGDSGGPLVC-KALSGRWFLAGLVSWGL--GCGRPNYFGVYTRITGVISWIQQVV 823          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Match: svh-1 (HGF/MSP/plasminogen-like protein [Source:UniProtKB/TrEMBL;Acc:Q17800])

HSP 1 Score: 50.8322 bits (120), Expect = 2.170e-6
Identity = 60/256 (23.44%), Postives = 99/256 (38.67%), Query Frame = 1
Query:  619 CGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLK---DTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGL--SYGIYMRVPQVALWIRKMI 1371
            CG ++++   ++TAAHC E  E V   E                 ++VGD +      +E +  L     +P Y   + +  +D+A+L++  P     +   P    S+DF      +C   GWG +     +R                         LQ   +P+++   C      ++       CAG YL+   D+C GDSGG   C  +    + L G+ ++G  +GC      GIY  V     WI  +I
Sbjct:  740 CGASILDKTHLITAAHCFEEDERVSSYE-----------------VVVGDWDNNQTDGNEQIFYLQRIHFYPLY---KDIFSHDIAILEIPYPGIEFNEYAQPICLPSKDFVYTPGRQCVVSGWGSMGLRYAER-------------------------LQAALIPIINRFDCVNSSQIYSSMSRSAFCAG-YLEGGIDSCQGDSGGPFACRREDGAFV-LAGVISWG--DGCAQKKQPGIYTMVAPYLSWISAII 946          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG10663 (gene:FBgn0036287 transcript:FBtr0346570)

HSP 1 Score: 109.768 bits (273), Expect = 3.278e-25
Identity = 112/416 (26.92%), Postives = 168/416 (40.38%), Query Frame = 1
Query:  277 YESWSGWTICQSDSCTKSRFRVCR------NSLKRTKNY----------WPRQRKCETKYIYEKSTCNDTAECATNNYSKEERIS-------------------KLPKKCGIMSNNAAN-------KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNK--CYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLK--DTCSGDSGGGLFCVDDTSKRLH---LYGITNFGLAEGCGL--SYGIYMRVPQVALWIRKMI 1371
            Y  WS WT C S  CT  R++ CR        + R   Y          W + +  +T     +      A       S++  +S                    L   CGI+ +           KI GG+ A K +W   V   ++  +   + CGGTLI P WVLTAAHC+  +  VR                      +G+HN       EI   +     HP+  FD+     DVALL+L   + ++  + Y C+ +    F  L     C  +GWG       KR N               R +  +SVL +  +P++ ++ C K +  + + K +  CAG      DTC+GDSGG L C  DT+K  H   ++GIT+FG  +GC     +GIY +VP    W+  ++
Sbjct:  381 YSKWSRWTKC-SPKCTTRRYKKCRIMDQCGREVLREIAYCYTEGSFCQQWLQTQFQKTPAFETRPGSGSPANAMRRMQSEQPEVSMNDLNYIMTGKGYRGPEYTPLKLSCGIVRSGTGRRSMSNMLKIIGGRAARKGEWPWQVA--ILNRFKEAF-CGGTLIAPRWVLTAAHCVRKVLFVR----------------------IGEHNLNYEDGTEIQLRVMKSYTHPN--FDKRTVDSDVALLRLPKAVNATTWIGYSCLPQP---FQALPKNVDCTIIGWG-------KRRN---------------RDATGTSVLHKATVPIIPMQNCRKVYYDYTITKNM-FCAGHQKGHIDTCAGDSGGPLLC-RDTTKPNHPWTIFGITSFG--DGCAQRNKFGIYAKVPNYVDWVWSVV 739          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG10663 (gene:FBgn0036287 transcript:FBtr0113167)

HSP 1 Score: 109.768 bits (273), Expect = 3.278e-25
Identity = 112/416 (26.92%), Postives = 168/416 (40.38%), Query Frame = 1
Query:  277 YESWSGWTICQSDSCTKSRFRVCR------NSLKRTKNY----------WPRQRKCETKYIYEKSTCNDTAECATNNYSKEERIS-------------------KLPKKCGIMSNNAAN-------KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNK--CYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLK--DTCSGDSGGGLFCVDDTSKRLH---LYGITNFGLAEGCGL--SYGIYMRVPQVALWIRKMI 1371
            Y  WS WT C S  CT  R++ CR        + R   Y          W + +  +T     +      A       S++  +S                    L   CGI+ +           KI GG+ A K +W   V   ++  +   + CGGTLI P WVLTAAHC+  +  VR                      +G+HN       EI   +     HP+  FD+     DVALL+L   + ++  + Y C+ +    F  L     C  +GWG       KR N               R +  +SVL +  +P++ ++ C K +  + + K +  CAG      DTC+GDSGG L C  DT+K  H   ++GIT+FG  +GC     +GIY +VP    W+  ++
Sbjct:  381 YSKWSRWTKC-SPKCTTRRYKKCRIMDQCGREVLREIAYCYTEGSFCQQWLQTQFQKTPAFETRPGSGSPANAMRRMQSEQPEVSMNDLNYIMTGKGYRGPEYTPLKLSCGIVRSGTGRRSMSNMLKIIGGRAARKGEWPWQVA--ILNRFKEAF-CGGTLIAPRWVLTAAHCVRKVLFVR----------------------IGEHNLNYEDGTEIQLRVMKSYTHPN--FDKRTVDSDVALLRLPKAVNATTWIGYSCLPQP---FQALPKNVDCTIIGWG-------KRRN---------------RDATGTSVLHKATVPIIPMQNCRKVYYDYTITKNM-FCAGHQKGHIDTCAGDSGGPLLC-RDTTKPNHPWTIFGITSFG--DGCAQRNKFGIYAKVPNYVDWVWSVV 739          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: Np (gene:FBgn0265011 transcript:FBtr0112560)

HSP 1 Score: 82.8037 bits (203), Expect = 2.286e-16
Identity = 73/291 (25.09%), Postives = 125/291 (42.96%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYL-EIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIH---VCAGTYLK---DTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIK 1374
            +I GG  A   +W   +     +     + CG  L+N  W +TAAHC++ +     L  +G+             Y L  +     Y E  +    SH       +FD    +YD+ALL+   P+    ++   C+ ++ + F+  T   +  GWG L    P                         SVLQEV +P+++  +C   + S    + I    +CAG + K   D+C GDSGG +    ++ KR HL G+ ++G+  GC  +   G+Y R+ +   WI ++++
Sbjct:  797 RIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDLLLRLGE-------------YDLAEEEEPYGYQERRVQIVASH------PQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENFIGQT--AFVTGWGRLYEDGPL-----------------------PSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAG-WKKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISWGI--GCAEANQPGVYTRISEFRDWINQILQ 1040          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: Np (gene:FBgn0265011 transcript:FBtr0307883)

HSP 1 Score: 82.8037 bits (203), Expect = 2.286e-16
Identity = 73/291 (25.09%), Postives = 125/291 (42.96%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYL-EIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIH---VCAGTYLK---DTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIK 1374
            +I GG  A   +W   +     +     + CG  L+N  W +TAAHC++ +     L  +G+             Y L  +     Y E  +    SH       +FD    +YD+ALL+   P+    ++   C+ ++ + F+  T   +  GWG L    P                         SVLQEV +P+++  +C   + S    + I    +CAG + K   D+C GDSGG +    ++ KR HL G+ ++G+  GC  +   G+Y R+ +   WI ++++
Sbjct:  797 RIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDLLLRLGE-------------YDLAEEEEPYGYQERRVQIVASH------PQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENFIGQT--AFVTGWGRLYEDGPL-----------------------PSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAG-WKKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISWGI--GCAEANQPGVYTRISEFRDWINQILQ 1040          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Match: CG9733 (gene:FBgn0039759 transcript:FBtr0085638)

HSP 1 Score: 77.7962 bits (190), Expect = 3.681e-15
Identity = 83/311 (26.69%), Postives = 136/311 (43.73%), Query Frame = 1
Query:  490 PKKCGIMSNNAANKIYGGKEAEKDK--WKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGE---------HEIMK-SLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLN-KTIHVCAG-TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIK 1374
            P  CG +     N+IY G++ + ++  W   + +       +   C G+LIN  +VLTAAHCL T  I R  E+G +++ RL           G+H+TR   +          E+ +       +H  Y      + +D+ L++               +  +  +  N+   C     GL +R   ++       F +  W R  +++R S+V Q+V +  VD   C +  S   +N +   +CAG  + KD+C GDSGG L    D S    L GI +FG    CGL    G+Y  V    +WIR+ ++
Sbjct:  150 PPSCGGV--GIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCL-TGRIER--EVGTLVSVRL-----------GEHDTRTAVDCPPGGGSCSPEVQRLGFEEIRVHERYSEKASNQVHDIGLIR---------------MERNVRYSDNIQPICLPSSVGLESRQSGQQ-------FTVAGWGRTLKMAR-SAVKQKVTVNYVDPAKCRQRFSQIKVNLEPTQLCAGGQFRKDSCDGDSGGPLMRFRDES--WVLEGIVSFGYK--CGLKDWPGVYTNVAAYDIWIRQNVR 417          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: cela1.4 (chymotrypsin like elastase family member 1, tandem duplicate 4 [Source:ZFIN;Acc:ZDB-GENE-050626-127])

HSP 1 Score: 112.464 bits (280), Expect = 8.192e-28
Identity = 78/285 (27.37%), Postives = 125/285 (43.86%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIKN 1377
            ++ GG+ A+ + W   +    +   + ++ CGGTLI PGWVLTAAHC++                    I  ++ +++GDH+   +  HE   ++S   IHP++  D     YD+ALL+L      +  V    +  +     +  N+CY  GWG                       R       SS L++  LP+VD   CS+     ++ K   +C+G      C GDSGG L C+ +    +H  G+T+F  A GC  +    ++ RV     WI  +I N
Sbjct:   29 RVVGGEVAKPNSWPWQISLQFLSALDYFHTCGGTLIRPGWVLTAAHCVD--------------------IPRNWRVILGDHDITKHEGHEQSLTVSRVYIHPNWNTDSVSSGYDIALLQLSTDATLNSYVQLATLPPAGQVLPH-NNECYITGWG-----------------------RTQTGGSTSSQLKQALLPVVDHNTCSRSDWWGSIVKDTMICSGGGEVSGCQGDSGGPLNCLVNGKYVVH--GVTSFVSAAGCNTNKKPTVFTRVSAYNSWINAIIGN 267          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:123217 (zgc:123217 [Source:ZFIN;Acc:ZDB-GENE-051113-188])

HSP 1 Score: 111.694 bits (278), Expect = 5.944e-27
Identity = 94/313 (30.03%), Postives = 145/313 (46.33%), Query Frame = 1
Query:  463 SKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEI-VRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTI---HVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLY---GITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIK 1374
            S ++  ++   +CG+   N   +I GG +A    W   V  +    YN  ++CGGTLI+  WV+TAAHC+    I V  L +G+                    +T +   +E+   L   I+HPS  F+  L   D++L+KL  P+  S  +   C+A +   F N T  C+A GWG + +           D  L   Q           LQ+V++P+V   +CS E+ S N N TI    +CAG   K TC GDSGG   C     K+  ++   GIT++G + GC +     +Y RV +   WI+  ++
Sbjct:   16 STQDSNAQTTYECGVAPLNT--RIVGGTDAPAGSWPWQVSIH----YNNRHICGGTLIHSQWVMTAAHCIINTNINVWTLYLGRQ-----------------TQSTSVANPNEVKVGLQSIIVHPS--FNNSLLNNDISLMKLSQPVNFSQYIRPICLAANNSIFYNGT-SCWATGWGNIGK-----------DQALPAPQT----------LQQVQIPVVANSLCSTEYESVN-NATITPQMICAGKANKGTCQGDSGGPFQC-----KQGSVWIQAGITSYGTSAGCAVGAYPDVYSRVSEFQSWIKMNVQ 275          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: cela1.3 (chymotrypsin like elastase family member 1, tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-040801-12])

HSP 1 Score: 99.7525 bits (247), Expect = 2.931e-23
Identity = 76/284 (26.76%), Postives = 121/284 (42.61%), Query Frame = 1
Query:  526 NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMI 1371
             ++ GG+ A+ + W   +    +   + Y+ CGG+LI PGWV+TAAHC+++    R                    +++GDH+   +   E   S+S   IHP++  +     YD+ALL+L      +  V    +  S     N  N CY  GWG                    R Q    +S +   L++  LP+VD   CS+     +  K   +C G      C GDSGG L C    S +  ++G+T+F  + GC  +    ++ RV     WI  +I
Sbjct:   28 GRVVGGEVAKPNSWPWQISLQYLSGSSYYHTCGGSLIRPGWVMTAAHCVDSPRTWR--------------------VVLGDHDIYNHEGREQYISVSRAHIHPNWNSNSLSSGYDIALLELSSDASLNSYVQLAALPPSGQVLPN-NNPCYISGWG--------------------RTQTGGSLSAE---LKQAYLPVVDHDTCSRSDWWGSTVKNTMICGGDGTLAGCHGDSGGPLNC--QVSGQYVVHGVTSFVSSAGCNTNKRPTVFSRVSAYISWINDVI 265          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: ela2 (elastase 2 [Source:ZFIN;Acc:ZDB-GENE-041117-1])

HSP 1 Score: 94.3597 bits (233), Expect = 2.496e-21
Identity = 78/288 (27.08%), Postives = 124/288 (43.06%), Query Frame = 1
Query:  526 NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMK-SLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIKN 1377
            +++ GG +   + W            + Y+ CGGTLI+  WVLTAAHC+ +    R                    +L+G HN  +  E      S +  I+H ++  D Y  + D+AL+KL  P+  +  ++  C+ +S     +  + CY  GWG L                   W   P     + +LQ+  LP+VD   C+K     NL   + VCAG   +  +C+GDSGG L C         ++GI +FG + GC       ++ RV     WI K++ +
Sbjct:   26 SRVVGGSDVRPNSWPWQASLQYQSGSSFYHTCGGTLIDKQWVLTAAHCISSSRTYR--------------------VLLGKHNLPLSSESGSQAISPARIIVHENW--DSYNIRNDIALIKLSTPVTFTDKISPACLPDSGSILPH-NSPCYVTGWGRL-------------------WTGGP----IADILQQALLPIVDQATCTKSDWWGNLVTDLMVCAGGDGVVSSCNGDSGGPLNC-QRRDGTWDVHGIVSFGSSLGCNYPKKPSVFTRVSGYIPWINKVMTS 266          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Match: ela2 (elastase 2 [Source:ZFIN;Acc:ZDB-GENE-041117-1])

HSP 1 Score: 92.8189 bits (229), Expect = 7.102e-21
Identity = 77/288 (26.74%), Postives = 124/288 (43.06%), Query Frame = 1
Query:  526 NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMK-SLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIKN 1377
            +++ GG +   + W            + Y+ CGGTLI+  WVLTAAHC+ +                       + +L+G HN  +  E      S +  I+H ++  D Y  + D+AL+KL  P+  +  ++  C+ +S     +  + CY  GWG L                   W   P     + +LQ+  LP+VD   C+K     NL   + VCAG   +  +C+GDSGG L C         ++GI +FG + GC       ++ RV     WI K++ +
Sbjct:   26 SRVVGGSDVRPNSWPWQASLQYQSGSSFYHTCGGTLIDKQWVLTAAHCISS---------------------RTYRVLLGKHNLPLSSESGSQAISPARIIVHENW--DSYNIRNDIALIKLSTPVTFTDKISPACLPDSGSILPH-NSPCYVTGWGRL-------------------WTGGP----IADILQQALLPIVDQATCTKSDWWGNLVTDLMVCAGGDGVVSSCNGDSGGPLNC-QRRDGTWDVHGIVSFGSSLGCNYPKKPSVFTRVSGYIPWINKVMTS 265          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: anp32c (acidic nuclear phosphoprotein 32 family member C [Source:Xenbase;Acc:XB-GENE-991758])

HSP 1 Score: 107.071 bits (266), Expect = 1.479e-25
Identity = 90/303 (29.70%), Postives = 144/303 (47.52%), Query Frame = 1
Query:  496 KCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFN----LNKTIHVCAGTYL---KDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            +CGI    ++ +I GG+ A ++KW   V    ++D N  + CGG+LIN  WV++AAHC+     V                  D +  +    T I  + EI  ++   I+HP  R+D+Y    D++LL+L+  +  +  +   C+  +   F     KC+A GWG +    P                 NP+I      LQEV LP++D + CS+  S+ +    ++  + +CAG Y+   KDTC GDSGG L C ++   R +L GI ++G +  CG  Y  G+   +P    WI   + N
Sbjct:   13 ECGI--PQSSERIMGGQAAAQNKWPWQVS---LRDTNGRHFCGGSLINNKWVVSAAHCINNPRSV------------------DLHCPITSIGT-IPNQQEIRVAVMRIIVHP--RYDKYSSINDISLLELENEVVLTDAIIPVCLPTAAVTFPTGL-KCWATGWGAILPGVP---------------LPNPKI------LQEVALPMIDSQTCSQYFSTPSTKAAISPNLMICAG-YIDGGKDTCQGDSGGPLVCSEN--NRWYLGGIVSYGAS--CGKPYRPGVNTFLPPFIGWIESTVPN 262          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: dkk2 (dickkopf WNT signaling pathway inhibitor 2 [Source:Xenbase;Acc:XB-GENE-480441])

HSP 1 Score: 100.138 bits (248), Expect = 1.359e-21
Identity = 86/300 (28.67%), Postives = 139/300 (46.33%), Query Frame = 1
Query:  490 PKKCGI--MSNNAA-NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAG---TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRK 1365
            P  CG+  MS  +A  +I GG+EA  + W   V    +K ++    CGG +I+P WVLTAAHC+   E   ++                  I+ GDH+  +    E ++++    IH  Y  + Y    D+ALL L+ PL  +  +   C+ E  +  +  T+ C   GWG                             + +  LQ++ LP++D K+C++ +    +   + +CAG   +  KD C GDSGG L C  +T ++  +YG+ ++G  EGCG  Y  G+Y +V     WI+K
Sbjct:  533 PDVCGMAPMSQKSALPRIIGGEEACPNCWPWQVRILFLKAFH----CGGAIISPQWVLTAAHCIRASEPSYWV------------------IVAGDHDRMLNESMEQIRNIKAIRIHEDYNSENY--DNDIALLYLEEPLEFNDFLRPVCLPEPEEA-LTPTSLCVVTGWG-----------------------NTAEGGQPALRLQQLHLPILDSKICNESYYPGQMTNHM-LCAGFPSSKAKDACQGDSGGPLVC-GNTKEQYFIYGLVSWG--EGCGQVYKPGVYTKVRLFLTWIQK 780          

HSP 2 Score: 62.003 bits (149), Expect = 1.478e-9
Identity = 63/244 (25.82%), Postives = 101/244 (41.39%), Query Frame = 1
Query:  604 NVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSK--EHSSFNLNKTIHVCAG--TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYG 1323
            N  ++CGG+++    V+TAAHC+  +   +                    ++ G+++ ++    E    +S    HP YR    +  YD+AL+ L  P+     V   C+ +  +  + +   C + GWG                    R + N  +   S VLQEV+LP++    CS   E     L     +CAG     +D C GDSGG L C    S    L G  ++G+  GCG  +G
Sbjct:   77 NERHICGGSIVRKDMVVTAAHCVYPVTEKK---------------VSHMTVIAGEYDQQVNDSQEQSIPVSRIEPHPDYRGGGKMS-YDIALIFLAKPIVFGSQVQPICLPQVGE-KLEIGTLCVSSGWG--------------------RLEENGEL---SPVLQEVKLPIIGNATCSSVLESMGLPLLDDSMLCAGFPEGGRDACQGDSGGPLVC-RRRSGVWFLAGCVSWGV--GCGRIWG 277          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: dkk2 (dickkopf WNT signaling pathway inhibitor 2 [Source:Xenbase;Acc:XB-GENE-480441])

HSP 1 Score: 98.2117 bits (243), Expect = 5.518e-21
Identity = 88/297 (29.63%), Postives = 139/297 (46.80%), Query Frame = 1
Query:  499 CGI--MSNNAA-NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAG---TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRK 1365
            CG+  MS  +A  +I GG+EA  + W   V    +K ++    CGG +I+P WVLTAAHC+   E   ++                  I+ GDH+  +    E ++++    IH  Y  + Y    D+ALL L+ PL  +  +   C+ E  +  +  T+ C   GWG          N  E      R             LQ++ LP++D K+C++ +    +   + +CAG   +  KD C GDSGG L C  +T ++  +YG+ ++G  EGCG  Y  G+Y +V     WI+K
Sbjct:  518 CGMAPMSQKSALPRIIGGEEACPNCWPWQVRILFLKAFH----CGGAIISPQWVLTAAHCIRASEPSYWV------------------IVAGDHDRMLNESMEQIRNIKAIRIHEDYNSENY--DNDIALLYLEEPLEFNDFLRPVCLPEPEEA-LTPTSLCVVTGWG----------NTAEGGQPALR-------------LQQLHLPILDSKICNESYYPGQMTNHM-LCAGFPSSKAKDACQGDSGGPLVC-GNTKEQYFIYGLVSWG--EGCGQVYKPGVYTKVRLFLTWIQK 762          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: cnih4 (cornichon family AMPA receptor auxiliary protein 4 [Source:Xenbase;Acc:XB-GENE-993717])

HSP 1 Score: 89.3521 bits (220), Expect = 1.987e-19
Identity = 77/289 (26.64%), Postives = 114/289 (39.45%), Query Frame = 1
Query:  523 ANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXV---NYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCA-GTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMI 1371
            A ++ GG  A K+ W   V    +     Y+ CG +LI    VLTAAHC++ +                      F +++GDHN       E   S+S  + H ++  +     YD+A+L L      +  V   N P  A+      N    C   GWG                       R       +SVLQ+  L +V    CS      +  KT  VCA G  ++ +C+GDSGG L C  +   ++H  GI +FG A GC +     ++ RV     WI   +
Sbjct:   26 AVRVVGGTNAAKNAWPWQVSLQYLSGSAWYHTCGASLIRANRVLTAAHCVDRVV--------------------SFRVVLGDHNINANDGTEQYISVSKIVKHANWNTNNVAAGYDIAVLHLASSATLNTSVKLANLP--ADGAILAHNY--GCIVTGWG-----------------------RTSTGGALASVLQQAPLSVVQHSTCSSSSWWGSTVKTTMVCADGAGIRSSCNGDSGGPLNCAVNGVYQVH--GIVSFGSASGCNIVQKPSVFTRVSAYIAWINSAL 265          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Match: cnih4 (cornichon family AMPA receptor auxiliary protein 4 [Source:Xenbase;Acc:XB-GENE-993717])

HSP 1 Score: 89.7373 bits (221), Expect = 2.483e-19
Identity = 78/287 (27.18%), Postives = 114/287 (39.72%), Query Frame = 1
Query:  523 ANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXV---NYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCA-GTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRK 1365
            A ++ GG  A K+ W   V    +     Y+ CG +LI    VLTAAHC++ +                      F +++GDHN       E   S+S  + H ++  +     YD+A+L L      +  V   N P  A+      N    C   GWG                       R       +SVLQ+  L +V    CS      +  KT  VCA G  ++ +C+GDSGG L C  +   ++H  GI +FG A GC +     ++ RV     WI K
Sbjct:   26 AVRVVGGTNAAKNAWPWQVSLQYLSGSAWYHTCGASLIRANRVLTAAHCVDRVV--------------------SFRVVLGDHNINANDGTEQYISVSKIVKHANWNTNNVAAGYDIAVLHLASSATLNTSVKLANLP--ADGAILAHNY--GCIVTGWG-----------------------RTSTGGALASVLQQAPLSVVQHSTCSSSSWWGSTVKTTMVCADGAGIRSSCNGDSGGPLNCAVNGVYQVH--GIVSFGSASGCNIVQKPSVFTRVSAYIAWINK 263          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Cela3b (chymotrypsin-like elastase family, member 3B [Source:MGI Symbol;Acc:MGI:1915118])

HSP 1 Score: 102.449 bits (254), Expect = 3.855e-24
Identity = 79/297 (26.60%), Postives = 125/297 (42.09%), Query Frame = 1
Query:  499 CGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRI-YGEHEIMK-SLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGL--SYGIYMRVPQVALWIRKMIKN 1377
            CG  S+N ++++  G+EA    W   V     KD + ++ CGG+LI P WVLTA HC+ T                       + +++G+H   +  G+ +++  +     +HP +         D+AL+KL         V   C+  + +   N    CY  GWG L+   P                           LQ+  LP+VD + CS+ +      KT  VCAG  ++  C+GDSGG L C  D      ++G+T+F  + GC       ++ RV     WI + I N
Sbjct:   17 CGQPSHNPSSRVVNGEEAVPHSWPWQVSLQYEKDGSFHHTCGGSLITPDWVLTAGHCISTSRT--------------------YQVVLGEHERGVEEGQEQVIPINAGDLFVHPKWNSMCVSCGNDIALVKLSRSAQLGDAVQLACLPPAGEILPN-GAPCYISGWGRLSTNGPLPDK-----------------------LQQALLPVVDYEHCSRWNWWGLSVKTTMVCAGGDIQSGCNGDSGGPLNCPADNGT-WQVHGVTSFVSSLGCNTLRKPTVFTRVSAFIDWIEETIAN 268          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Prss30 (protease, serine 30 [Source:MGI Symbol;Acc:MGI:1353645])

HSP 1 Score: 98.9821 bits (245), Expect = 1.551e-22
Identity = 87/314 (27.71%), Postives = 135/314 (42.99%), Query Frame = 1
Query:  487 LPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRF------DRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSK----EHSSFNLNKTIH---VCAGTYL---KDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIK 1374
            LP  CG   +  A KI GG++A + +W   V  ++ +D    ++CGG+LI+  WVLTAAHC             + +N         +++ VG     +   H  + ++ +  +HP+Y +      D  L Q D  L               P         +     C+  GWG             E D               +SVLQE+ +PL+D + C K    + SS +  + I    +CAG Y+   KD+C GDSGG L C  ++S      GIT++G+  GC   Y  G+Y RVP    WI++++ 
Sbjct:   24 LPSVCG--HSRDAGKIVGGQDALEGQWPWQVSLWITEDG---HICGGSLIHEVWVLTAAHCFR-----------RSLNPSF------YHVKVGGLTLSLLEPHSTLVAVRNIFVHPTYLWADASSGDIALVQLDTPLRPSQFTPVCLPAAQTP---------LTPGTVCWVTGWGATQ----------ERDM--------------ASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAG-YVEGQKDSCQGDSGGPLVCSINSSWT--QVGITSWGI--GCARPYRPGVYTRVPTYVDWIQRILA 277          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Prss30 (protease, serine 30 [Source:MGI Symbol;Acc:MGI:1353645])

HSP 1 Score: 98.9821 bits (245), Expect = 1.551e-22
Identity = 87/314 (27.71%), Postives = 135/314 (42.99%), Query Frame = 1
Query:  487 LPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRF------DRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSK----EHSSFNLNKTIH---VCAGTYL---KDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIK 1374
            LP  CG   +  A KI GG++A + +W   V  ++ +D    ++CGG+LI+  WVLTAAHC             + +N         +++ VG     +   H  + ++ +  +HP+Y +      D  L Q D  L               P         +     C+  GWG             E D               +SVLQE+ +PL+D + C K    + SS +  + I    +CAG Y+   KD+C GDSGG L C  ++S      GIT++G+  GC   Y  G+Y RVP    WI++++ 
Sbjct:   24 LPSVCG--HSRDAGKIVGGQDALEGQWPWQVSLWITEDG---HICGGSLIHEVWVLTAAHCFR-----------RSLNPSF------YHVKVGGLTLSLLEPHSTLVAVRNIFVHPTYLWADASSGDIALVQLDTPLRPSQFTPVCLPAAQTP---------LTPGTVCWVTGWGATQ----------ERDM--------------ASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAG-YVEGQKDSCQGDSGGPLVCSINSSWT--QVGITSWGI--GCARPYRPGVYTRVPTYVDWIQRILA 277          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Plg (plasminogen [Source:MGI Symbol;Acc:MGI:97620])

HSP 1 Score: 93.5893 bits (231), Expect = 8.904e-20
Identity = 86/317 (27.13%), Postives = 132/317 (41.64%), Query Frame = 1
Query:  433 DTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLK--DTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN 1377
            D   CA+ +  +  +    PKKC         ++ GG  A    W   +       +   + CGGTLI P WVLTAAHCLE      +                 + +++G H   I G      S++  I+ P+ R        D+ALLKL  P   +  V   C+  S ++ +     CY  GWG             +  F   R             L+E +LP+++ KVC++     N  K+  +CAG      D+C GDSGG L C +    +  L G+T++GL        G+Y+RV +   WI + ++N
Sbjct:  556 DIPLCASASSFECGKPQVEPKKC-------PGRVVGGCVANPHSWPWQISLRT--RFTGQHFCGGTLIAPEWVLTAAHCLEKSSRPEF-----------------YKVILGAHEEYIRGLDVQEISVAKLILEPNNR--------DIALLKLSRPATITDKVIPACLP-SPNYMVADRTICYITGWG-----------ETQGTFGAGR-------------LKEAQLPVIENKVCNRVEYLNNRVKSTELCAGQLAGGVDSCQGDSGGPLVCFE--KDKYILQGVTSWGLGCARPNKPGVYVRVSRFVDWIEREMRN 811          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Match: Prss36 (protease, serine 36 [Source:MGI Symbol;Acc:MGI:1924863])

HSP 1 Score: 92.8189 bits (229), Expect = 1.610e-19
Identity = 90/295 (30.51%), Postives = 127/295 (43.05%), Query Frame = 1
Query:  517 NAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHS---SFNLNKTI---HVCAG--TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGL--SYGIYMRVPQVALWIRKMI 1371
              +++I GG +A    W   V  +        ++CGG+LI P WVL+AAHC  T             N  L    D+  +L+G H+     E   M+S++  +I  +Y         D+ALL+L  P      V   C+  +   F + T  C+A GWG +    P     + L +                VLQEVEL L+    C   +S    FNL   +    +CAG     +DTC GDSGG L C D    R  L GIT+FG   GCG     G++  V     WIR+ +
Sbjct:   43 EPSSRIVGGSDAHPGTWPWQVSLH----QGGGHICGGSLIAPSWVLSAAHCFVT-------------NGTLEPA-DELSVLLGVHSQDGPLEGAHMRSVATILIPDNYSTVEL--GADLALLRLASPAKLGPSVRPVCLPRASHLFAHGT-ACWATGWGDVQEAVP-----LPLPW----------------VLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGYPAGRRDTCQGDSGGPLVCED--GGRWFLAGITSFGF--GCGRRNRPGVFTAVAPYESWIREHV 291          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|P00773|CELA1_RAT (Chymotrypsin-like elastase family member 1 OS=Rattus norvegicus OX=10116 GN=Cela1 PE=1 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 2.565e-26
Identity = 80/285 (28.07%), Postives = 127/285 (44.56%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIK 1374
            ++ GG EA ++ W + +    +   + Y+ CGGTLI   WV+TAAHC+ +          +M           F ++VGDHN       E   S+   ++HP++  +     YD+ALL+L   +  +  V    + +      N  N CY  GWG                    R + N ++S+    LQ+  LP VD  +CS      +  KT  VCAG   ++  C GDSGG L C+ +    +H  G+T+F  + GC +S    ++ RV     W+  +I 
Sbjct:   26 RVVGGAEARRNSWPSQISLQYLSGGSWYHTCGGTLIRRNWVMTAAHCVSS----------QM----------TFRVVVGDHNLSQNDGTEQYVSVQKIMVHPTWNSNNVAAGYDIALLRLAQSVTLNNYVQLAVLPQEGTILAN-NNPCYITGWG--------------------RTRTNGQLSQT---LQQAYLPSVDYSICSSSSYWGSTVKTTMVCAGGDGVRSGCQGDSGGPLHCLVNGQYSVH--GVTSFVSSMGCNVSKKPTVFTRVSAYISWMNNVIA 264          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|O46644|CELA1_MACFA (Chymotrypsin-like elastase family member 1 OS=Macaca fascicularis OX=9541 GN=CELA1 PE=2 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 1.109e-24
Identity = 78/286 (27.27%), Postives = 125/286 (43.71%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            ++ GG EA ++ W + +    +   + Y+ CGGTLI   WV+TAAHC+++ +                     F ++VGDHN       E   S+   ++HP +  +     YD+ALL+L   +  +  V    + +      N  + CY  GWG                    R + N ++++    LQ+  LP VD  +CS      +  K   VCAG   +   C GDSGG L C+ +    +H  G+T+F   +GC +S    ++ RV     WI K I +
Sbjct:   26 RVVGGTEAGRNSWPSQISLQYLSGGSWYHTCGGTLIRQNWVMTAAHCVDSPK--------------------TFRVVVGDHNLSQNDGTEQYVSVQKIVVHPYWNSNNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILAN-DSPCYITGWG--------------------RTKTNGQLAQ---TLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVHSGCQGDSGGPLHCLVNGKYSVH--GVTSFVSKQGCNVSRKPTVFTRVSAYISWINKTIAS 265          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q28153|CELA1_BOVIN (Chymotrypsin-like elastase family member 1 OS=Bos taurus OX=9913 GN=CELA1 PE=2 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 2.213e-24
Identity = 79/286 (27.62%), Postives = 124/286 (43.36%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            ++ GG    K+ W + +        + Y+ CGGTLI   WV+TAAHC+++          +M           F +++GDHN       E   S+   ++HPS+  +     YD+A+L+L      +  V    + +S     N T  CY  GWG                    R + N ++++    LQ+  LP VD   CS      +  KT  VCAG   ++  C GDSGG L C+ +    +H  G+T+F  + GC +S    ++ RV     WI   I +
Sbjct:   26 RVVGGTAVSKNSWPSQISLQYKSGSSWYHTCGGTLIKQKWVMTAAHCVDS----------QM----------TFRVVLGDHNLSQNDGTEQYISVQKIVVHPSWNSNNVAAGYDIAVLRLAQSATLNSYVQLGVLPQSGTILANNT-PCYITGWG--------------------RTKTNGQLAQT---LQQAYLPSVDYATCSSSSYWGSTVKTTMVCAGGDGVRAGCQGDSGGPLHCLVNGQYAVH--GVTSFVSSLGCNVSKKPTVFTRVSAYISWINNAIAS 265          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q867B0|CELA1_CANLF (Chymotrypsin-like elastase family member 1 OS=Canis lupus familiaris OX=9615 GN=CELA1 PE=2 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 4.511e-24
Identity = 76/286 (26.57%), Postives = 127/286 (44.41%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            ++ GG EA ++ W + +    +     Y+ CGGTLI   WV+TAAHC++     R +                F +++G+HN       E   S+   ++HP +  +     YD+ALL+L   +  +  V    + +      N  + CY  GWGL                     + N ++++   VLQ+  LP VD  +CS      ++ K   VCAG   ++  C GDSGG L C    + +  ++G+T+F  + GC +S    ++ RV     WI  +I +
Sbjct:   18 RVVGGTEARRNSWPSQISLQYLSGGKWYHTCGGTLIRQNWVMTAAHCVD-----RTMT---------------FRVVIGEHNLSQNDGTEQSASVQKIVVHPYWNSNDVSAGYDIALLRLAQKVTLNSYVQLGVLPQEGAILAN-NSPCYITGWGLT--------------------KTNGQLAQ---VLQQAYLPTVDYAICSSSSYWGSIVKKSMVCAGGDGIRSGCQGDSGGPLHC--SVNGKYTVHGVTSFVSSLGCNVSRKPTVFTRVSAYITWINNVIAS 257          
BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5R1M5|CELA1_FELCA (Chymotrypsin-like elastase family member 1 OS=Felis catus OX=9685 GN=CELA1 PE=2 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 1.060e-23
Identity = 78/286 (27.27%), Postives = 124/286 (43.36%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGT-YLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIKN 1377
            ++ GG EA K+ W + +    +     Y+ CGGTLI   WV+TAAHC++           KM           F ++ G+HN       E   S+   ++HP +  +     YD+ALL+L   +  +  V    +  +     N  N CY  GWG+                     + N ++++    LQ+  LP VD   CS      +  K+  VCAG   ++  C GDSGG L C+ +    +H  G+T+F  + GC +S    ++ RV     WI  +I +
Sbjct:   26 RVVGGTEARKNPWPSQISLQYLSGGKWYHTCGGTLIRQNWVMTAAHCVDR----------KM----------TFRVVAGEHNLSQNDGTEQRVSVQKIVVHPYWNSNNVAAGYDIALLRLAQRVTLNNYVQLGVLPAAGTILAN-NNPCYITGWGMT--------------------KTNGQLAQA---LQQAYLPSVDYATCSSSSYWGSTVKSTMVCAGGDGIRSGCQGDSGGPLHCLVNGKYAVH--GVTSFVSSLGCNVSRKPTVFTRVSAYISWINNVIAS 265          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A0V0J9M6 (Chymotrypsin-like elastase family member 2A (Fragment) OS=Schistocephalus solidus OX=70667 GN=CEL2A PE=3 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 5.771e-54
Identity = 141/430 (32.79%), Postives = 205/430 (47.67%), Query Frame = 1
Query:  178 QSEDMVEMFQRQRQIEKEEFTMNKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCRNSL--KRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAA--NKIYGGKEAEKDKWKAHVGFYV------------IKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYIL--VGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNK--CYAVGWGLLNRYKPKRSNYIEL-------DFDLERW--QRNPRISRKSSV---LQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMI 1371
            Q+ED    F  Q   ++    + + I  + ++ Y  WS W  C    CT+ RFR C++     R  + + R + C   YI E   C DT+ C  +  S  E +  L   CG+ + +A    KI GGK A    W      Y              + Y     CGGTLI P WV+TAAHCL  +   + L IG+  +    G   D  +   +GDH+  +  + +   ++   IIHP YR       +DVALLKL         + + C+ +     M+L     CYA GWG ++    + +N+ +        DF +  +  Q+ PR SR+      L EVELPLV L+ C +  +  NL + +HVCAG   KDTC GDSGGGLFC +   KR +LYG+T+FG   GCG  YG+Y     ++ WI  ++
Sbjct:   57 QTEDK---FFTQYVFDRNTLILRRRIMLYKDNLYTEWSDWGNCSVKDCTEFRFRRCKDESYENRITDLF-RTKSCPFLYIAETRECRDTSLCKADGPS--ELLKNLSTTCGVRNVDAPFQTKILGGKTAVPHSWPWQAALYAGMRNAGLRAHYSRRKYIEAPFCGGTLIAPSWVVTAAHCLTELIPHKELPIGQPFSIEEVG---DIIVRARLGDHSRSVIEKKQRDHNIQTAIIHPDYRRGFSENGFDVALLKLAEDAEFQETIGHICVPDKN---MSLPEGLVCYAAGWGDMSADSAQDNNFFDFIYGTGLSDFFVNPFFNQQPPRRSRRPQQPLQLVEVELPLVSLQRCRRYFN--NLREGVHVCAGAKGKDTCRGDSGGGLFCQNPVDKRWYLYGVTSFGSGRGCGKYYGVYTCTRGISDWIHGIL 472          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A158R6J8 (Peptidase S1 domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS358 PE=3 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 2.411e-52
Identity = 137/416 (32.93%), Postives = 200/416 (48.08%), Query Frame = 1
Query:  220 IEKEEFTMNKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWP---RQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSN-----NAANKIYGGKEAEKDKWKAHVGFYVIKDYNV-----------YYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDH-NTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLN---RYKPKRSNYIEL--------DFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIK 1374
            +++    + ++IF F N+ Y  WS W+ C +  CT+ R+R C N     +NY P   R   C  +YI E   C + AEC     SK   + +L   CG   N       + KI GG+EA+   W   V  YV +   V              CG TLI P W++TAAHCL  +   + L +G++ +     +       +GDH   R  G  E+ + +   IIHP YR     + +DVALLKLD P+     V+  CI + +   +   + CYA GWG  +      P+   +I+            L +  R  R  R+   L EV+LPLV L+ C +     NL + +HVCAG   KDTC GDSGGGLFC +    + ++YG+T+FG   GCG  YG+Y     ++ WI   ++
Sbjct:   48 MDRGTLLLRRKIFIFRNELYTPWSDWSNCSTRDCTELRYRQCLND--SYENYIPNLFRTNNCPFQYIVETRRCANDAECHKEAPSKI--LKELASTCGKRPNFKSKRGTSPKILGGREAKPHSWPWQVALYV-RPLAVEGRSSRSATIESPFCGATLIAPSWLITAAHCLSELVPDKVLTVGQVFSVE-EELEQSIRARIGDHVRGRRDGPQEVSRLIELAIIHPDYRRGFSEQGFDVALLKLDEPVEFGDKVSPICIPD-KSLHLPEGHTCYAAGWGATSPDTAVLPEPLGFIDFFSASLFPRPCGLGQSNRRCRGPRQPLRLLEVDLPLVSLQRCRRTFR--NLREWVHVCAGEKGKDTCRGDSGGGLFCQNPEDGKWYIYGVTSFGSVVGCGEHYGVYACTRGISDWIHGNVQ 454          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A504YAC3 (Mastin OS=Fasciola gigantica OX=46835 GN=FGIG_00425 PE=3 SV=1)

HSP 1 Score: 192.586 bits (488), Expect = 9.357e-52
Identity = 136/401 (33.92%), Postives = 193/401 (48.13%), Query Frame = 1
Query:  253 IFTFWNDDYESWSGWTICQSDSCTKSRFRVC-RNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAA--NKIYGGKEAEKDKWKAHVGFYV-IKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDD-FYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFD-----------------------LERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMI 1371
            +  F  + Y +WS W+ C S +C + R R C  +S K          +C +KY  EK TC +  +C++  Y   + +  L + CGI  N  A   KI GGKE +   W   V   V          CGGTLI P W+LTAAHCL  +E  R + +GK +  RL+       Y  +GDHN +   E +    +   I+HP Y         D+ALL L  P+    +VNY C+   +D  +    KCYA+GWG     KP   + ++  FD                       +   +R  R     S L EV LP+V +  C + +   ++N  +H+CAG   KDTCSGDSGGGL+C D ++ R  + G+T+FGLA GCGL+ G+Y  V     WI K +
Sbjct:  103 LIVFNTERYGNWSDWSECISKACIEVRHRKCLDDSWKTPSPSRVHTTRCLSKYYAEKRTCQNETQCSS--YIGAQMVENLTETCGIRPNGKAVRMKITGGKETKPHSWPWVVSPSVKPPGGKPITFCGGTLIAPQWILTAAHCL-LVETKR-MPVGKPV--RLSDHMKSVIYAHLGDHNKKKKEEVQQDYRVDVAILHPRYHRSLMTDGDDIALLHLTEPVEIKPEVNYVCLP-PKDMQLKPGTKCYALGWGNTVAGKPPTFDNLQGLFDSILLPFPSFFGSPFGSPFGGMFGMHGKRRRQRRPATPSELHEVALPIVSVDECRRHYG--DVNNELHICAGAKGKDTCSGDSGGGLYCHDPSNDRWTVVGVTSFGLARGCGLNPGVYTSVIAHMDWIAKQL 494          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A4E0R3S3 (Mastin OS=Fasciola hepatica OX=6192 GN=D915_004913 PE=3 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 1.072e-51
Identity = 135/397 (34.01%), Postives = 192/397 (48.36%), Query Frame = 1
Query:  253 IFTFWNDDYESWSGWTICQSDSCTKSRFRVC-RNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAA--NKIYGGKEAEKDKWKAHVGFYVIKDYN-VYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDD-FYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFD-------------------LERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMI 1371
            +  F  + Y +WS W+ C S +C + R R C  +S K          +C +KY  EK TC +  +C++  Y   + +  L + CGI  N  A   KI GGKE +   W   V   V          CGGTLI P W+LTAAHCL  +E  R + +GK +  RL+       Y  +GDH+ +   E +    +   I+HP Y         D+ALL L  P+    +VNY C+   +D  +    KCYA+GWG     KP   + ++  FD                   +    R  R     S L EV LP+V +  C + +   ++N  +H+CAG   KDTCSGDSGGGL+C D ++ R  + G+T+FGLA GCGL+ G+Y  V     WI K +
Sbjct:  103 LIVFNTERYGNWSDWSECISKACIEVRHRKCLDDSWKTPSPSRVHTTRCLSKYYAEKRTCQNETQCSS--YIGAQMVENLTETCGIRPNGKAVRMKITGGKETKPHSWPWVVRLSVKPPRGKPITFCGGTLIAPQWILTAAHCL-LVETKR-MPVGKPV--RLSDHMKSVIYAHLGDHDKKKKEEVQQDYRVDVAILHPRYHRSLMTDGDDIALLHLTEPVEIKPEVNYVCLP-PKDMQLKPGTKCYALGWGNTVAGKPPTFDNLQGLFDSILLPFPSFFGSPFGGMFGMHGKGRRQRRPATPSELHEVALPIVSVDECRRHYG--DVNNELHICAGAKGKDTCSGDSGGGLYCHDPSNDRWTVVGVTSFGLARGCGLNPGVYTSVVAHMDWIAKQL 490          
BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Match: A0A4Z2CWF4 (Tryptase isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_006927 PE=3 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 1.414e-50
Identity = 125/403 (31.02%), Postives = 199/403 (49.38%), Query Frame = 1
Query:  244 NKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWP-RQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGI--MSNNAANKIYGGKEAEKDKWKAHVGFYV-IKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWG-------------------LLNRYKPKRSNYIELDF---DLERWQ-RNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMI 1371
            ++EI+ F  + Y +WS W  C    C + R+R C +   +T +  P    +C +KY  EK TC++  +C  N Y+ ++ I  L   CGI  + N    KI GGK  E   W   V   V +        CGGTLI P W+LTAAHC+      +++ +GK +      +    Y  +GDH+       ++   ++  I+HP+Y        YD+ALL++  P+ +  ++++ C+   ++  +    KCYAVGWG                   L   +    S+     F   D+  W  +N      S  L EVELP+V ++ C K ++  +++  +HVCAG   KDTC+GDSGGGL+C  + + +  + G+T+FGLA GCGL+ G+Y        W+ K +
Sbjct:   13 SQEIYVFNTERYSNWSDWKECLPMECIEIRYRKCLDDSWKTLSPNPIHTTRCISKYYAEKRTCSNKTQC--NAYTGDQIIKNLTNTCGIRKLENEIQTKILGGKVVEPHSWPWAVRLSVKLPRRKSVTFCGGTLIAPQWILTAAHCVLVEN--KHIPVGKPV-ILADHMKSTIYAHLGDHDRYKQEPSQMDYRVTVAILHPNYHRKLQTDGYDIALLRISEPVKTKPEIDFACLP-PKNLNLPPNTKCYAVGWGSNKGAKVPTFDNIHSILESLFLPFPTLFSSTFMPSFGRRDINLWNLKNLESEESSKELHEVELPIVSIENCRKHYA--DISSKVHVCAGAKNKDTCAGDSGGGLYCQLENTNQWFVVGVTSFGLARGCGLNPGVYTSTSSHMDWLTKQL 407          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000045670.1 (pep primary_assembly:Astyanax_mexicanus-2.0:15:32397968:32408849:1 gene:ENSAMXG00000037630.1 transcript:ENSAMXT00000045670.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 99.7525 bits (247), Expect = 4.570e-23
Identity = 76/258 (29.46%), Postives = 117/258 (45.35%), Query Frame = 1
Query:  520 AANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCS-KEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNF 1290
              N++  G+EA+   W   +          Y+ CGGTLI P WVLTA HC+   +I R                    I++G+H+  +    E ++ +   ++HP +  +      D+ALLKLD     + +V   CI  + +   + T  CY  GWG L+ + P                    I  K   LQ+  LP+V+  VCS K+    N+  T+ VCAG  ++  C+GDSGG L C   T  R ++ G+T+F
Sbjct:   58 VTNRVVNGQEAKPHSWPWQISLQFKHGSRWYHTCGGTLIAPRWVLTAGHCIFPGDIYR--------------------IVLGEHDLSVQEGTEQIRDILRIVVHPKWNIECVACGNDMALLKLDKAPVLNENVQTACIPPAGEILPHDT-PCYISGWGDLDTHGP--------------------IPDK---LQQAMLPVVEYSVCSQKDWWGINVKPTM-VCAGGDIRSGCNGDSGGPLNC-KGTDGRWYIQGVTSF 269          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: si:dkey-32n7.9 (chymotrypsin-like protease CTRL-1 [Source:NCBI gene;Acc:103029386])

HSP 1 Score: 98.2117 bits (243), Expect = 2.345e-22
Identity = 85/304 (27.96%), Postives = 138/304 (45.39%), Query Frame = 1
Query:  481 SKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAE-SRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHS-SFNLNKTIH-VCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLY---GITNFGLAEGCGLSYGIYMRVPQVALWIRKMIK 1374
            ++    CG    N   +I GG  A+   W   V  +    +   ++CGGTLI+  WVLTAAHC+ +++   ++                  + +G  N      +E+ + +   I+HPSY  +  L   DV L++L  P+  S  +   C+A  S  F+ N T  C++ GWGLL   +                      S  S  LQEVE+P+V    C+  +  + + N T   +CAG+  K TC GDSGG L C     K+  ++   G+T++G++   G+   +Y RV +   WI + + 
Sbjct:   22 AQTENSCGFAPLN--TRIVGGANAQAGNWPWQVSMH----HQDQHICGGTLIHQEWVLTAAHCILSLDTSNWM------------------LYLGRENQSTANPNEVSRGVQEIIMHPSY--NNTLFNNDVTLMRLSSPVNFSDYIRPICLASNSSTFYSNTT--CWSTGWGLLRHNE----------------------SLASETLQEVEVPVVGNSQCACNYQVAKDANITAQMICAGSAGKGTCQGDSGGPLQC-----KQGSVWVQAGVTSYGISCAAGIPE-VYARVSEFQSWITENVA 269          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: cela1.6 (elastase-1-like [Source:NCBI gene;Acc:103040289])

HSP 1 Score: 95.9005 bits (237), Expect = 1.215e-21
Identity = 73/277 (26.35%), Postives = 114/277 (41.16%), Query Frame = 1
Query:  550 AEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMIK 1374
            A    W   +    +   + Y+ CGG+LI   WV+TAAHC++T    R                    +++GDH+   +   E   S+S+  IHPS+  +     YD+ALL+L      +  V    +  S     N  N CY  GWG                       R       S+ L++  LP+VD   CS      +  KT  VCAG      C GDSGG L C    + + +++G+T+F   +GC +     ++ RV     W+  +++
Sbjct:   85 ARPHSWPWQISLQYLSGGSYYHTCGGSLIRRRWVMTAAHCVDTSRTWR--------------------VVLGDHDIYTHEGTEQYMSVSNVYIHPSWNSNNVAGGYDIALLRLSADASLNSYVQLANLPPSGQVLPN-NNPCYITGWG-----------------------RTQTGGNLSAQLKQASLPVVDHSTCSSSSWWGSTVKTTMVCAGGGSLSGCQGDSGGPLNC--QVNGKYYVHGVTSFVSGQGCNVQRKPTVFTRVSAYISWLESIMQ 315          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: cela1.6 (elastase-1-like [Source:NCBI gene;Acc:103040289])

HSP 1 Score: 94.7449 bits (234), Expect = 4.489e-21
Identity = 73/275 (26.55%), Postives = 112/275 (40.73%), Query Frame = 1
Query:  550 AEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKM 1368
            A    W   +    +   + Y+ CGG+LI   WV+TAAHC++T    R                    +++GDH+   +   E   S+S+  IHPS+  +     YD+ALL+L      +  V    +  S     N  N CY  GWG                       R       S+ L++  LP+VD   CS      +  KT  VCAG      C GDSGG L C    + + +++G+T+F   +GC +     ++ RV     W+  +
Sbjct:   85 ARPHSWPWQISLQYLSGGSYYHTCGGSLIRRRWVMTAAHCVDTSRTWR--------------------VVLGDHDIYTHEGTEQYMSVSNVYIHPSWNSNNVAGGYDIALLRLSADASLNSYVQLANLPPSGQVLPN-NNPCYITGWG-----------------------RTQTGGNLSAQLKQASLPVVDHSTCSSSSWWGSTVKTTMVCAGGGSLSGCQGDSGGPLNC--QVNGKYYVHGVTSFVSGQGCNVQRKPTVFTRVSAYISWLESV 313          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Match: cela1.6 (elastase-1-like [Source:NCBI gene;Acc:103040289])

HSP 1 Score: 92.0485 bits (227), Expect = 3.274e-20
Identity = 71/253 (28.06%), Postives = 103/253 (40.71%), Query Frame = 1
Query:  550 AEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGC 1308
            A    W   +    +   + Y+ CGG+LI   WV+TAAHC++T    R                    +++GDH+   +   E   S+S+  IHPS+  +     YD+ALL+L      +  V    +  S     N  N CY  GWG                       R       S+ L++  LP+VD   CS      +  KT  VCAG      C GDSGG L C    S +  ++G+T+F  + GC
Sbjct:   85 ARPHSWPWQISLQYLSGGSYYHTCGGSLIRRRWVMTAAHCVDTSRTWR--------------------VVLGDHDIYTHEGTEQYMSVSNVYIHPSWNSNNVAGGYDIALLRLSADASLNSYVQLANLPPSGQVLPN-NNPCYITGWG-----------------------RTQTGGNLSAQLKQASLPVVDHSTCSSSSWWGSTVKTTMVCAGGGSLSGCQGDSGGPLNC--QVSGQYVVHGVTSFVSSLGC 291          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006511.1 (pep scaffold:Pmarinus_7.0:GL476457:197255:208031:1 gene:ENSPMAG00000005872.1 transcript:ENSPMAT00000006511.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 97.0561 bits (240), Expect = 5.184e-23
Identity = 77/288 (26.74%), Postives = 126/288 (43.75%), Query Frame = 1
Query:  517 NAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAE-SRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKMI 1371
            +A N+I  G EA    W              Y+VCGG+L+   WV+TAAHC++   + R                    +++G HN RI    +   +++  ++HPS+        +D+AL+KL    P S  +    +    ++ + N+T  C A GWGLL                           +  SVLQE +LP V+   CS++   +    T  +CAG      C+GDSGG L C +     + +YGIT+FG  + C + +   ++ RV     W+ +++
Sbjct:   25 SAQNRIVNGVEAAPHTWPWQASLQAQTGTGWYHVCGGSLVQQQWVMTAAHCIQADRVYR--------------------MVLGKHNLRINEPAQFESTIALSVVHPSWNNHPTRGWFDIALMKLSSAAPLSEQIKLAVLPRVGQELWDNVT--CMATGWGLLASD-----------------------GKFPSVLQEAKLPFVNYSTCSQQEWWWYGVNTNLICAGDD-HAVCNGDSGGPLSCQEPNGSWV-VYGITSFG-HKNCSVFHKPSVFTRVSAYTDWVSQVM 264          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009421.1 (pep scaffold:Pmarinus_7.0:GL476822:99973:112424:1 gene:ENSPMAG00000008474.1 transcript:ENSPMAT00000009421.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 96.6709 bits (239), Expect = 7.607e-23
Identity = 77/297 (25.93%), Postives = 121/297 (40.74%), Query Frame = 1
Query:  502 GIMSNNAANKIYGGKEAEKDKWKAHV----GFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYR--FDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIRKM 1368
            GI  N    +I  G++A  + W   +     ++     ++Y+ CGG L+N  WVLTAAHC+    +  Y +                 +L+G  N  ++ E ++   + +  +HP +   F  Y   +D+A ++L+   P +  +  P         ++   +CYA GWG L+   P                         S LQ+ +LP V    CS         K   +CAG  L  TC GDSGG L C  D    +H  GIT+FG    C       ++ RV   + WI  +
Sbjct:   22 GIKINLQQARIVNGEDAVPNSWPWQISLATAWFPESPNDIYHTCGGVLLNSDWVLTAAHCI----VTNYSQ----------------SVLLGKQNLHLFEEGQLHVQIKNIHVHPKWNALFPEY--GFDLAFIELNESAPITNKIQ-PATLPYPGHILSNNPECYATGWGSLSTDGPS-----------------------PSTLQQAKLPFVSYAKCSSSEYWGTTVKPSMICAGDSLHSTCYGDSGGPLNCKTDRGWEVH--GITSFGFPTSCNFDTKPNVFTRVSGYSAWITSI 270          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009363.1 (pep scaffold:Pmarinus_7.0:GL476822:37454:60557:-1 gene:ENSPMAG00000008427.1 transcript:ENSPMAT00000009363.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.5893 bits (231), Expect = 7.484e-22
Identity = 78/298 (26.17%), Postives = 122/298 (40.94%), Query Frame = 1
Query:  493 KKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYN----VYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCG--LSYGIYMRVPQVALWIRKM 1368
            K  GI  N    +I  G++A  + W   +      D      + + CGG L+N  WVLTAAHC               INT  +       + +G HN     E ++   + +  +HP++      + +D+AL++L+  +P +  +  P         ++   +CYA GWG+L+   P                         S LQ+V+LP V    C+       + K   +CAG  L   C+GDSGG L C  D    +H  GIT+F    GC       ++ RV   + WI  +
Sbjct:   16 KPQGIKINLQQARIVNGEDAAPNSWPWQISLATAWDPESPDVINHTCGGVLLNTDWVLTAAHC---------------INTSFSQ-----SVCLGKHNLITLEEGQLHVQIKNIHVHPNWNATFVERGFDLALIELNESVPITNKIQ-PATLPYPGHILSNNPECYATGWGILSTDGPS-----------------------PSTLQQVKLPFVSYAECNSSEYWGTIVKPSMICAGDSLHSACNGDSGGPLNCKTDRGWEVH--GITSFVSNFGCNYYTKPSVFTRVSGYSAWITSI 267          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001315.1 (pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-1 gene:ENSPMAG00000001180.1 transcript:ENSPMAT00000001315.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.8113 bits (216), Expect = 2.080e-19
Identity = 101/346 (29.19%), Postives = 151/346 (43.64%), Query Frame = 1
Query:  379 PRQRKCET--KYIYEKSTCNDTAECATNNYSK----EERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVC--SKEHSSFNLNKTIHVCAG--TYLKDTC-SGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGL--SYGIYMRVPQVALWIRKMIKN 1377
            P Q +C    + +   + C+ +A+CA+ N  K    EE  +K   K         ++I GG+ A    W      +     N +  CGG+LI+P WVLTAAHC+           GK  N R+  +  D+ +  G       G  E  +S+   ++H  Y        YD+ALL+LD P+  +  V   C+  +   F+     C+  GWG +          I  +F L            S+ +QEV+LPL+    C  S +H++  +     +CAG     KD C  GDSGG L C D  S    L G+ ++G+  GCGL    G+Y RV     WI  +I  
Sbjct:   41 PMQFQCAAGAECVALSAVCSGSADCASGNDEKSCLGEEPAAKRMVK---------SRIVGGESALAGAWPWQASLWSGLTKNHH--CGGSLIHPKWVLTAAHCV----------YGK--NCRVEAL-SDWTLFFGKLLLDKEGPMEQHRSIRQIVVHRQYVSSE--NDYDIALLELDSPVNLTEQVQTVCMPAASHAFLP-GQMCWVSGWGTV----------IGNEFSL------------SNNMQEVQLPLISQSDCIGSYDHATPRM-----LCAGYPDGGKDACQQGDSGGPLVCEDRGS--WFLAGLVSWGV--GCGLVNKPGVYTRVTAFTKWINSIIAQ 328          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005493.1 (pep scaffold:Pmarinus_7.0:GL476632:243920:250733:-1 gene:ENSPMAG00000004970.1 transcript:ENSPMAT00000005493.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 6.602e-19
Identity = 76/284 (26.76%), Postives = 120/284 (42.25%), Query Frame = 1
Query:  526 NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIF-DDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIK 1374
            ++I  G+EA    W   V     +    ++ CGG+LI+P WV+TAAHC                     GI   +  +++G+H+     E     +++  I HP  ++D      DVAL+KL  P   +  V+  C++ + D F    N C   GWG+ N +          D D       PR       LQ+  L +V    C +  ++ N    + +CAG     +C  DSGG L C  D +   +L GI ++G +        +Y RV  +  WI + I 
Sbjct:   25 SRIVNGEEAMPGSWPWQVSL---QSKTGFHFCGGSLIDPYWVVTAAHC---------------------GISPSEHRVILGEHDRSSSSEKVQTMTIAKAINHP--QWDNMSINNDVALIKLSQPAQMTDGVSAVCLSSTSDNFPPGLN-CVTSGWGITNNF----------DSDTP-----PR-------LQQTALAIVATPTCQQLLANMNKITDVMICAGGAGATSCRRDSGGPLVCEKDGA--WNLVGIVSWGNSSCSTRIPAVYTRVTAIRSWIDQTIA 257          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO47761 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKX8])

HSP 1 Score: 93.5893 bits (231), Expect = 9.050e-22
Identity = 88/283 (31.10%), Postives = 119/283 (42.05%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNV-YYVCGGTLINPGWVLTAAHCLE-TIEIVRY-LEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLK--DTCSGDSGGGLFCVD-DTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWI 1359
            +I GG  A+   W   V     K ++     CGG+LI+P WVLTAAHC E T +  +Y L +G+       G   DFYI                     + IHP Y  D      D+AL+KLD P   +  VN  C+ E+ D F   T KC   GWG L                             S VL + ++PLV    CS + S  +      +CAG      D+C GDSGG   C + +  ++  L G+T++G      L YGIY  V +   WI
Sbjct:    1 RIVGGVVAKPGAWPWQVALIWAKGHDKGAQFCGGSLIDPEWVLTAAHCFEITKDKSQYMLRLGEHNFNEDEGTEQDFYI-------------------EKYYIHPKY--DEKTTDNDMALIKLDRPATLNKRVNTICLPEADDEFKPGT-KCTISGWGALQE----------------------GAGSTSKVLMQAKVPLVSRDQCSHQQSYGDRITENMLCAGMRQGGVDSCQGDSGGPFVCTNPENPRQWTLVGVTSWGKGCARALKYGIYANVRRYLHWI 239          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO44208 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW61])

HSP 1 Score: 91.6633 bits (226), Expect = 3.129e-21
Identity = 77/285 (27.02%), Postives = 123/285 (43.16%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKS--LSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDT---CSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKM 1368
            +I  G+ A+   W   +    ++  + ++ CGG+LI+  WV+TAAHC+               N    G    + ++VG H  R  G   + +S  LS  I HP Y   R +    +  L   +   S+  V   C+ + R        +CY  GWG +N                   Q++P I      LQ+  LP+   + C +++   +++ T H+CAG    D    C+GDSGG L C D+ S  LH  G  ++GL       Y ++ RV     WI++M
Sbjct:    2 RIINGQNAQPHSWPWQIS---LRGRSGFHTCGGSLISDRWVVTAAHCIHR-------------NKNPGG----YTVVVGAHKKR--GSTSVQQSLRLSQIIEHPKYNDRRIVNDIALIELATPVQFDSAGKVGTVCLTDQRPA---PGKRCYITGWGAINGDT----------------QQSPDI------LQQAMLPIASHENCRRKYG--DVSSTAHLCAGEARSDAAGGCNGDSGGPLVCEDNGSWFLH--GAVSYGLRNCPTTHYTVFARVASYTDWIKRM 235          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO46103 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR41])

HSP 1 Score: 88.9669 bits (219), Expect = 2.273e-20
Identity = 78/259 (30.12%), Postives = 115/259 (44.40%), Query Frame = 1
Query:  613 YVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTY--LKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIKN 1377
            ++CGG+++N  W++TAAHC+ T         G    T  A  F D  + +G+H        E    +   ++HPSY        YD+ALLKL  P+  +  V+  C+ +  D  +  T  CY  GWG +    P                        S+VLQE  +PLVD + C +++ +         CAG Y   K TC GDSGG L C  ++  R  L G+T++    GC  S   G+Y  V     WIR+ +  
Sbjct:    3 HICGGSIVNSQWIVTAAHCVTT------KPPGASRYTMYA--FSDLNVTLGEHQLYQLDGSEQNIPIEGIVVHPSYND----LDYDIALLKLRQPITFNAYVSQVCLPQ--DALLAGT-PCYVSGWGRIGESSP-----------------------GSNVLQEASIPLVDQRACEEQYRNLKPITARMRCAGIYGTPKGTCKGDSGGPLVC--ESKGRWVLMGVTSWSY-NGCADSGYAGVYADVVYFKDWIRQTVST 220          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: EDO34065 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQF0])

HSP 1 Score: 89.7373 bits (221), Expect = 2.303e-20
Identity = 84/292 (28.77%), Postives = 122/292 (41.78%), Query Frame = 1
Query:  526 NKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLK--QYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLT--NKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYL--KDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIRKMIKN 1377
            ++I GG+EA ++ W   V   +       + CGG+LI+P W+LT++HC  T                   I   F I +G+H+ R Y   E +       IHP       +    YDVAL+KL  P      V   C+        NLT   KCY  GWG      P                        S VL EVE+ +V  +VC+   S        + CAG     +D+C GDSGG L C +   + + L G+ ++G  EGC     YG+Y+ V ++  +I   I+ 
Sbjct:    3 SRIVGGREAPRNSWPWQVEIILKTPNLTTHYCGGSLIDPYWILTSSHCFWTYN----------------NISTQFEIRLGEHDVRKYEGFEEIIQGDQLYIHPGLVVGDLISPGDYDVALIKLKRPAVFHKRVYSVCLPS---VTANLTTGTKCYVTGWGKTAEGSP-----------------------YSPVLNEVEVDIVSKEVCNANDSYNGTINDRYFCAGFTQGGRDSCGGDSGGPLVCPNADGQYV-LRGVVSWG--EGCARPKKYGVYLDVRRILPFIEGTIEG 249          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Match: NVMASP (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ55])

HSP 1 Score: 93.2041 bits (230), Expect = 3.392e-20
Identity = 88/291 (30.24%), Postives = 140/291 (48.11%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEI-MKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRD--FFMNLTNKCYAVGWG-LLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHV-CAG--TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLS--YGIYMRVPQVALWIR-KMI 1371
            +I GG +  K  +  HV   +I+    +  CGG+LI+  WVLTAAHC      V +     +  +R       F + +G + T +  E ++ ++++S    HP  +FD  L   D+AL+KLD     S  V   C+ E+ D    ++ +    AVGWG  + R                  Q +  +   +  L+E  +P+V+  VC++       + T ++ CAG  +  KD C GDSGGG    D   ++  L G+ ++G + GCGL   YG+Y+RV Q   WIR +MI
Sbjct:  401 RIVGGHDTVKGAYPWHV---LIRK-GGHVACGGSLISEKWVLTAAHC------VTHRNGNILPRSR-------FQVQLGLYRTTLPNEPQVQLRNISEIRTHP--QFDHVLFDADLALIKLDGEAIISEYVRPICLPETDDQASLISPSKFGMAVGWGKTVGR------------------QGDVSVKNLADALKETCMPIVNSHVCNQAFQDEGYSVTPNMFCAGQASGGKDICQGDSGGGFVLYDSAKQKWFLGGVVSWGSSLGCGLPNKYGVYVRVTQFLGWIRTRMI 654          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: CELA1 (elastase-1 [Source:NCBI gene;Acc:101156080])

HSP 1 Score: 108.612 bits (270), Expect = 2.172e-26
Identity = 76/260 (29.23%), Postives = 115/260 (44.23%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGC 1308
            ++ GG+ A  + W   +    +   + Y+ CGGTLI  GWV+TAAHC+++    R                    +++G+H+    G  E    +S   +HP +  +R    YD+ALL+L   +  +  V    +  S     +  N CY  GWGL +                            SS L+E  LP+VD   CS+     +  KT  VCAG   +  C+GDSGG L C    S + +++GIT+FG A GC
Sbjct:   31 RVVGGEVASPNSWPWQISLQYLSGGSYYHTCGGTLIQRGWVMTAAHCVDSSRTWR--------------------VVLGEHDIYSSGGTEQYIGVSQVYVHPQWDSNRVSNGYDIALLRLASDVTLNSYVQLASLPPSGQILPH-NNLCYITGWGLTSTG-----------------------GSLSSQLKEAYLPVVDHSTCSRSDWWGSTVKTTMVCAGGGAESGCNGDSGGPLNC--QVSGKYYVHGITSFGSAYGC 244          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: CELA1 (elastase-1 [Source:NCBI gene;Acc:101155843])

HSP 1 Score: 101.679 bits (252), Expect = 5.689e-24
Identity = 72/260 (27.69%), Postives = 111/260 (42.69%), Query Frame = 1
Query:  529 KIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGC 1308
            ++ GG+ A  + W   +    +   + Y+ CGG+LI  GWV+TAAHC+++    R                    +++G+H+    G  E +  +S   IHP +  +R    YD+ALL+L      +  V    +  S     +  N CY  GWGL +                            SS L+E  LP+VD   CS+     +  KT  VC G   +  C+GDSGG L C    S + +++GI +F    GC
Sbjct:   31 RVVGGQVASPNSWPWQISLQYLSGGSYYHTCGGSLIQRGWVMTAAHCVDSSRTWR--------------------VVLGEHDIYSSGGTEQVIGVSQVYIHPQWDSNRVANGYDIALLRLSSDATLNSYVQLASLPPSGQILPH-NNLCYITGWGLTSTG-----------------------GSLSSQLKEAYLPVVDHSTCSRSDWWGSTVKTTMVCGGGGAESGCNGDSGGPLNC--QVSGKYYVHGIASFVSGYGC 244          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000035554.1 (elastase-1 [Source:NCBI gene;Acc:101156319])

HSP 1 Score: 98.2117 bits (243), Expect = 1.033e-22
Identity = 74/265 (27.92%), Postives = 114/265 (43.02%), Query Frame = 1
Query:  514 NNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGC 1308
            +N  +++ GG+ A  + W   +    +   + Y+ CGG+LI  GWV+TAAHC++     R                    ++VGDH+       E   S+S   +HPS+  +     YD+ALL+L  P   +  V    +  S     +  N CY  GWG                    R Q   ++S +   L++  LP+VD   CS      +  K+  VCAG   +  C GDSGG L C  +    +H  G+T+F  + GC
Sbjct:   28 DNLQDRVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGSLIKTGWVMTAAHCVDRSMTWR--------------------VVVGDHDIYTNEGREQYLSVSQVYVHPSWNTNNVAAGYDIALLRLSTPATLNSYVQLASLPPSGQVLPH-NNNCYISGWG--------------------RTQTGGQLSAQ---LKQAYLPVVDHNTCSSSGWWGSTVKSSMVCAGGGSESGCQGDSGGPLNCSVNGQWVVH--GVTSFVSSSGC 246          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000008752.2 (elastase-1 [Source:NCBI gene;Acc:101156319])

HSP 1 Score: 97.8265 bits (242), Expect = 1.140e-22
Identity = 74/265 (27.92%), Postives = 114/265 (43.02%), Query Frame = 1
Query:  514 NNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGC 1308
            +N  +++ GG+ A  + W   +    +   + Y+ CGG+LI  GWV+TAAHC++     R                    ++VGDH+       E   S+S   +HPS+  +     YD+ALL+L  P   +  V    +  S     +  N CY  GWG                    R Q   ++S +   L++  LP+VD   CS      +  K+  VCAG   +  C GDSGG L C  +    +H  G+T+F  + GC
Sbjct:   28 DNLQDRVVGGEVARPNSWPWQISLQYLSGGSYYHTCGGSLIKTGWVMTAAHCVDRSMTWR--------------------VVVGDHDIYTNEGREQYLSVSQVYVHPSWNTNNVAAGYDIALLRLSTPATLNSYVQLASLPPSGQVLPH-NNNCYISGWG--------------------RTQTGGQLSAQ---LKQAYLPVVDHNTCSSSGWWGSTVKSSMVCAGGGSESGCQGDSGGPLNCSVNGQWVVH--GVTSFVSSSGC 246          
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000008668.2 (transmembrane protease serine 11D [Source:NCBI gene;Acc:101163815])

HSP 1 Score: 92.0485 bits (227), Expect = 2.230e-20
Identity = 85/315 (26.98%), Postives = 141/315 (44.76%), Query Frame = 1
Query:  445 CATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIY---GEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAES--RDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAG--TYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSY--GIYMRVPQVALWIR 1362
            C T   S +    + P    ++     ++I GG+EA +  W   V   +    N  + CGGT+++  WVLTA+HC       +YL+I +     +AG+             R++   G H  ++ +S   +H  Y  D +    D+ LL+L  P   +  V   C   S   +F +N T+ C+  GWG         S+Y +               R  + LQE E+ L++ + C++            +CAG  +   D+C GDSGG L C  ++  R ++ G+T+FG  E CGL    G+Y R+ + A W++
Sbjct:   14 CVTAPASTQHSCGQRP----LVGPPGMSRIVGGREAVEGAWPWQVSIQI----NSKHHCGGTILDSHWVLTASHCFS-----KYLQIFRSHVRVVAGL-------------RVWSDPGAHSQIRYISEMKMHEDY--DDFTSDSDIMLLRLRSPFNFTSHVQPACTPYSVTHEFVLNFTH-CFITGWG---------SSYYK--------------GRLMNNLQEAEVELIERRRCNQFTWYDGFITENMLCAGLESGAADSCQGDSGGALQCYSESDDRFYVVGVTSFG--EECGLPRRPGVYSRISRFADWLK 274          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000025143.1 (SMESG000025143.1)

HSP 1 Score: 793.882 bits (2049), Expect = 0.000e+0
Identity = 392/396 (98.99%), Postives = 396/396 (100.00%), Query Frame = 1
Query:  190 MVEMFQRQRQIEKEEFTMNKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN 1377
            MVEMFQRQRQIEKEEFTMNKEIFTFW+DDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETI+IVRYLEIGK+INTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVALLKLDLPLPSSLD+NYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN
Sbjct:    1 MVEMFQRQRQIEKEEFTMNKEIFTFWDDDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIKIVRYLEIGKIINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVALLKLDLPLPSSLDINYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN 396          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000025143.1 (SMESG000025143.1)

HSP 1 Score: 787.334 bits (2032), Expect = 0.000e+0
Identity = 389/393 (98.98%), Postives = 393/393 (100.00%), Query Frame = 1
Query:  199 MFQRQRQIEKEEFTMNKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN 1377
            MFQRQRQIEKEEFTMNKEIFTFW+DDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETI+IVRYLEIGK+INTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVALLKLDLPLPSSLD+NYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN
Sbjct:    1 MFQRQRQIEKEEFTMNKEIFTFWDDDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIKIVRYLEIGKIINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVALLKLDLPLPSSLDINYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN 393          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000025209.1 (SMESG000025209.1)

HSP 1 Score: 392.889 bits (1008), Expect = 4.658e-133
Identity = 200/457 (43.76%), Postives = 296/457 (64.77%), Query Frame = 1
Query:   52 LIN*MLDNVFSISVLAICICSQSTESTQGFPFPTLKSKHA-------KYQSEDMVEMFQRQRQIEKE-------EFTMNKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCR-NSLKRTKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN 1377
            L N ++  + ++  +A+ +      ST+      LKS H        K+   D  E F+ +R+ ++           +++++F +W  +Y++W+ WT C   +CTKSR+R C+ NS +     +  Q+KC  K+I+EK TC+D  EC  +N+SK   +S LPK CG       NKIYGG +A K+ W  HVG YVI      Y+CGGTLINPGWV+T AHCL+T + V  LE GK+I+TR   ++D F++++GDH+     ++E+ + LSHFIIHPS+R +     YDVALLKLD P+PS++ +++PC+ + +++ M+ + KC+AVGWG +    P      E D+ LERW++N R  RKSS+LQEVE+PLVD + C +++  FNLNK IH+CAG+ LKDTC GDSGGGLFC+D  +    LYGITNFG A GCG+SYG+Y+RV +V++WI +++K+
Sbjct:    7 LCNSIMRWIITLLAVAMIVILSEIVSTRH-----LKSSHNLNRRRFNKFWDNDGDEEFKERRKYQRRYGERKYTRLMLSRKMFYYWTSNYDNWTNWTACSPRNCTKSRYRKCKDNSWEENVIDFRLQKKCPVKFIFEKMTCDDIPECVKSNFSKLGNVSTLPKICGRRPMEIQNKIYGGDDAGKNSWPWHVGLYVIHRNRAIYICGGTLINPGWVITTAHCLKTKDKVSTLEFGKLIDTRKNDLYDSFHVIIGDHDRSTTSDNEMTRKLSHFIIHPSFRANYTSNLYDVALLKLDSPVPSNVGMSFPCVPQKKNYTMDESAKCFAVGWGDVEPNNPYNIWSFEFDYFLERWRKNRRTPRKSSILQEVEIPLVDFEKCKRQYRIFNLNKDIHMCAGSKLKDTCRGDSGGGLFCLDPKTNSWQLYGITNFGSARGCGMSYGVYIRVSEVSMWITEILKS 458          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000035925.1 (SMESG000035925.1)

HSP 1 Score: 204.142 bits (518), Expect = 4.530e-61
Identity = 133/381 (34.91%), Postives = 192/381 (50.39%), Query Frame = 1
Query:  244 NKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCRNSLKRTKNYWPRQRKCETKYIYEKSTCNDTAEC-ATNNYSKEERISKLPKKCG--IMSNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDD-FYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIK 1374
            ++ +F   ++ Y  W+ W+ C  + CTK R + C+N+           R C    I E + C+D   C  +N+   E+ +  LPK CG  I +    NKI GG+ A+K  W   V +      + Y+ CG TLI+  W +TAAHC      + Y       N  L  I DD  ++ +G ++     +   +  +SH  IHPSY    Y   YD ALLKL   +  + ++ +PCI    +F +  T+ CYA+GWG  +    K        FD +R             LQEV+LPL+  + C  ++    +N TIHVCAGT  KDTCSGDSGGGL+C+   + R  LYGI +FG +EGCG   G+Y RV     WI++ IK
Sbjct:   29 SESMFVINDNYYGDWTAWSECVLE-CTKYRSKHCKNA---------DSRVCPVSMIKEITACHDKVNCKQSNSVYHEKTLHNLPKNCGQTINTQFLLNKIVGGRPADKSAWPWIVSYGFKSGKDFYFKCGATLISENWAITAAHC------INYENTIFTKNGGLNKIDDDKIFLRIGAYHKTKLTKEAYITFVSHISIHPSYSNSEYYSNYDFALLKLKTAIKPNKNMTFPCIFADENFQLPETSTCYALGWGKQDIKGSKV-------FD-DR-------------LQEVQLPLISYEACKLDYEGIYINYTIHVCAGTKNKDTCSGDSGGGLYCIHPATNRWVLYGIISFGTSEGCGEISGVYARVSSAIYWIQQTIK 372          
BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Match: SMESG000035926.1 (SMESG000035926.1)

HSP 1 Score: 165.236 bits (417), Expect = 4.539e-47
Identity = 111/330 (33.64%), Postives = 168/330 (50.91%), Query Frame = 1
Query:  388 RKCETKYIYEKSTCNDTAECATNNYS-KEERISKLPKKCGIM-SNNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAAHCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSLSHFIIHPSYRFDRYLKQYDVAXXXXXXXXXXXXXVNYPCIAESRDFFMNLTNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVELPLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKRLHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMI 1371
            R C  K I E  +C+    C  +N S K   +  LPK CG   ++N  NKI GGK  + +KW   V    + +  ++  CG TLI+ GW +TAAHC+     + Y+     +           +I +G+++     + E    +SH ++HP Y  D  +  YD ALLKL+  +  S    +PCIA   +F +     CY VGW         ++N I   FD +R             LQE+++PLV  + C +E+ +  +N T+H+CAG+  KDTC+GDSG GL+C D  +K   LYGI +FG + GCG + G+Y R+     WI  ++
Sbjct:    7 RVCPVKIIMEMKSCD---CCGCDNISVKLTTLEGLPKTCGKRPTDNVRNKIIGGKPTQVNKWPWMVDLGSVINREMFINCGATLISDGWAITAAHCM-----IPYISQDYKLGVLTKVESKTKFINIGNYHRGFIDKGEYKAYISHIVVHPLYYNDDTVTIYDFALLKLENRIKDSN-AKFPCIANEINFRLTQNPLCYTVGWA-----TETQNNQI---FD-DR-------------LQEIQIPLVSYQKCHEEYFNIYINYTLHICAGSKKKDTCTGDSGNGLYCFDPFTKSWLLYGIVSFGTSLGCGNTIGVYARISAAIEWIANVV 305          
The following BLAST results are available for this feature:
BLAST of Peptidase S1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CELA11.831e-2326.22chymotrypsin like elastase 1 [Source:HGNC Symbol;A... [more]
CELA2A1.840e-2127.62chymotrypsin like elastase 2A [Source:HGNC Symbol;... [more]
CELA2B2.148e-2127.87chymotrypsin like elastase 2B [Source:HGNC Symbol;... [more]
CELA3A1.017e-1927.43chymotrypsin like elastase 3A [Source:HGNC Symbol;... [more]
TMPRSS61.345e-1928.96transmembrane serine protease 6 [Source:HGNC Symbo... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
svh-12.170e-623.44HGF/MSP/plasminogen-like protein [Source:UniProtK... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG106633.278e-2526.92gene:FBgn0036287 transcript:FBtr0346570[more]
CG106633.278e-2526.92gene:FBgn0036287 transcript:FBtr0113167[more]
Np2.286e-1625.09gene:FBgn0265011 transcript:FBtr0112560[more]
Np2.286e-1625.09gene:FBgn0265011 transcript:FBtr0307883[more]
CG97333.681e-1526.69gene:FBgn0039759 transcript:FBtr0085638[more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cela1.48.192e-2827.37chymotrypsin like elastase family member 1, tandem... [more]
zgc:1232175.944e-2730.03zgc:123217 [Source:ZFIN;Acc:ZDB-GENE-051113-188][more]
cela1.32.931e-2326.76chymotrypsin like elastase family member 1, tandem... [more]
ela22.496e-2127.08elastase 2 [Source:ZFIN;Acc:ZDB-GENE-041117-1][more]
ela27.102e-2126.74elastase 2 [Source:ZFIN;Acc:ZDB-GENE-041117-1][more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
anp32c1.479e-2529.70acidic nuclear phosphoprotein 32 family member C [... [more]
dkk21.359e-2128.67dickkopf WNT signaling pathway inhibitor 2 [Source... [more]
dkk25.518e-2129.63dickkopf WNT signaling pathway inhibitor 2 [Source... [more]
cnih41.987e-1926.64cornichon family AMPA receptor auxiliary protein 4... [more]
cnih42.483e-1927.18cornichon family AMPA receptor auxiliary protein 4... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cela3b3.855e-2426.60chymotrypsin-like elastase family, member 3B [Sour... [more]
Prss301.551e-2227.71protease, serine 30 [Source:MGI Symbol;Acc:MGI:135... [more]
Prss301.551e-2227.71protease, serine 30 [Source:MGI Symbol;Acc:MGI:135... [more]
Plg8.904e-2027.13plasminogen [Source:MGI Symbol;Acc:MGI:97620][more]
Prss361.610e-1930.51protease, serine 36 [Source:MGI Symbol;Acc:MGI:192... [more]
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BLAST of Peptidase S1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P00773|CELA1_RAT2.565e-2628.07Chymotrypsin-like elastase family member 1 OS=Ratt... [more]
sp|O46644|CELA1_MACFA1.109e-2427.27Chymotrypsin-like elastase family member 1 OS=Maca... [more]
sp|Q28153|CELA1_BOVIN2.213e-2427.62Chymotrypsin-like elastase family member 1 OS=Bos ... [more]
sp|Q867B0|CELA1_CANLF4.511e-2426.57Chymotrypsin-like elastase family member 1 OS=Cani... [more]
sp|Q5R1M5|CELA1_FELCA1.060e-2327.27Chymotrypsin-like elastase family member 1 OS=Feli... [more]
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BLAST of Peptidase S1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0V0J9M65.771e-5432.79Chymotrypsin-like elastase family member 2A (Fragm... [more]
A0A158R6J82.411e-5232.93Peptidase S1 domain-containing protein OS=Taenia a... [more]
A0A504YAC39.357e-5233.92Mastin OS=Fasciola gigantica OX=46835 GN=FGIG_0042... [more]
A0A4E0R3S31.072e-5134.01Mastin OS=Fasciola hepatica OX=6192 GN=D915_004913... [more]
A0A4Z2CWF41.414e-5031.02Tryptase isoform 1 OS=Schistosoma japonicum OX=618... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000045670.14.570e-2329.46pep primary_assembly:Astyanax_mexicanus-2.0:15:323... [more]
si:dkey-32n7.92.345e-2227.96chymotrypsin-like protease CTRL-1 [Source:NCBI gen... [more]
cela1.61.215e-2126.35elastase-1-like [Source:NCBI gene;Acc:103040289][more]
cela1.64.489e-2126.55elastase-1-like [Source:NCBI gene;Acc:103040289][more]
cela1.63.274e-2028.06elastase-1-like [Source:NCBI gene;Acc:103040289][more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000006511.15.184e-2326.74pep scaffold:Pmarinus_7.0:GL476457:197255:208031:1... [more]
ENSPMAT00000009421.17.607e-2325.93pep scaffold:Pmarinus_7.0:GL476822:99973:112424:1 ... [more]
ENSPMAT00000009363.17.484e-2226.17pep scaffold:Pmarinus_7.0:GL476822:37454:60557:-1 ... [more]
ENSPMAT00000001315.12.080e-1929.19pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-... [more]
ENSPMAT00000005493.16.602e-1926.76pep scaffold:Pmarinus_7.0:GL476632:243920:250733:-... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO477619.050e-2231.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO442083.129e-2127.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461032.273e-2030.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO340652.303e-2028.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
NVMASP3.392e-2030.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CELA12.172e-2629.23elastase-1 [Source:NCBI gene;Acc:101156080][more]
CELA15.689e-2427.69elastase-1 [Source:NCBI gene;Acc:101155843][more]
ENSORLT00000035554.11.033e-2227.92elastase-1 [Source:NCBI gene;Acc:101156319][more]
ENSORLT00000008752.21.140e-2227.92elastase-1 [Source:NCBI gene;Acc:101156319][more]
ENSORLT00000008668.22.230e-2026.98transmembrane protease serine 11D [Source:NCBI gen... [more]
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BLAST of Peptidase S1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000025143.10.000e+098.99SMESG000025143.1[more]
SMESG000025143.10.000e+098.98SMESG000025143.1[more]
SMESG000025209.14.658e-13343.76SMESG000025209.1[more]
SMESG000035925.14.530e-6134.91SMESG000035925.1[more]
SMESG000035926.14.539e-4733.64SMESG000035926.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031112 ID=SMED30031112|Name=Peptidase S1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1410bp
AGTTAAGCAACTTTTCAAGAGTCCACAGTCCATAATATATGAGAATACTA
ACTCATAAATTGAATGCTGGACAACGTATTTTCAATCTCAGTACTAGCGA
TTTGCATTTGCTCCCAGTCAACTGAATCTACCCAAGGATTTCCATTTCCC
ACATTGAAATCGAAACATGCAAAGTATCAGAGTGAGGATATGGTCGAAAT
GTTTCAAAGGCAAAGACAAATTGAAAAGGAAGAATTCACGATGAACAAGG
AAATCTTTACATTTTGGAATGATGATTATGAAAGTTGGTCAGGCTGGACC
ATTTGTCAGTCCGACAGTTGTACAAAATCTCGATTTAGAGTCTGCAGAAA
TTCATTAAAACGAACTAAGAATTATTGGCCAAGACAAAGGAAATGCGAGA
CTAAATATATTTACGAAAAATCAACTTGCAATGACACGGCAGAATGCGCA
ACAAATAATTATTCAAAAGAAGAAAGAATTTCAAAACTGCCAAAGAAATG
TGGCATCATGTCGAACAATGCTGCCAATAAAATCTACGGTGGAAAAGAAG
CCGAAAAAGATAAGTGGAAGGCGCATGTAGGATTTTATGTTATAAAAGAC
TATAATGTATATTATGTATGCGGAGGCACTTTAATTAATCCCGGGTGGGT
CCTAACTGCTGCTCACTGTTTGGAAACTATCGAGATTGTCAGATATCTTG
AAATTGGGAAAATGATAAATACAAGACTTGCAGGAATATTCGACGATTTC
TATATCCTAGTTGGAGATCATAACACACGGATTTACGGAGAACACGAAAT
TATGAAATCTTTAAGTCATTTTATTATTCACCCCTCTTATCGTTTCGATC
GCTATTTGAAACAATACGACGTTGCTTTATTAAAATTAGATTTACCTCTT
CCCTCAAGTCTCGATGTCAATTATCCATGCATTGCAGAATCTAGAGATTT
CTTCATGAACCTGACCAACAAATGTTATGCCGTGGGCTGGGGATTATTAA
ACAGATATAAACCAAAAAGATCCAATTACATTGAGTTGGATTTTGATTTG
GAAAGATGGCAAAGAAACCCACGAATTTCAAGGAAATCTAGCGTGCTTCA
GGAAGTAGAGCTTCCTTTAGTCGACTTAAAAGTGTGTTCCAAAGAACATT
CTAGTTTTAATCTCAATAAAACCATTCACGTTTGTGCTGGAACGTATTTA
AAGGACACTTGCAGTGGAGACAGTGGCGGTGGACTGTTCTGTGTTGATGA
CACATCCAAAAGGTTACATCTGTATGGGATCACTAATTTCGGACTAGCAG
AAGGTTGCGGATTAAGTTATGGAATTTATATGAGAGTTCCGCAAGTTGCA
CTCTGGATTAGAAAAATGATTAAAAATTAATAATTTTCTTTTTAATGAAT
ATATAATAGA
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protein sequence of SMED30031112-orf-1

>SMED30031112-orf-1 ID=SMED30031112-orf-1|Name=SMED30031112-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=439bp
MLDNVFSISVLAICICSQSTESTQGFPFPTLKSKHAKYQSEDMVEMFQRQ
RQIEKEEFTMNKEIFTFWNDDYESWSGWTICQSDSCTKSRFRVCRNSLKR
TKNYWPRQRKCETKYIYEKSTCNDTAECATNNYSKEERISKLPKKCGIMS
NNAANKIYGGKEAEKDKWKAHVGFYVIKDYNVYYVCGGTLINPGWVLTAA
HCLETIEIVRYLEIGKMINTRLAGIFDDFYILVGDHNTRIYGEHEIMKSL
SHFIIHPSYRFDRYLKQYDVALLKLDLPLPSSLDVNYPCIAESRDFFMNL
TNKCYAVGWGLLNRYKPKRSNYIELDFDLERWQRNPRISRKSSVLQEVEL
PLVDLKVCSKEHSSFNLNKTIHVCAGTYLKDTCSGDSGGGLFCVDDTSKR
LHLYGITNFGLAEGCGLSYGIYMRVPQVALWIRKMIKN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000421tail
Vocabulary: INTERPRO
TermDefinition
IPR001314Peptidase_S1A
IPR001254Trypsin_dom
IPR018114TRYPSIN_HIS
IPR009003Peptidase_S1_PA
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001314Peptidase S1A, chymotrypsin familyPRINTSPR00722CHYMOTRYPSINcoord: 223..237
score: 34.3
coord: 338..350
score: 59.91
coord: 145..160
score: 65.29
IPR001254Serine proteases, trypsin domainSMARTSM00020trypsin_2coord: 114..390
e-value: 1.7E-45
score: 167.1
IPR001254Serine proteases, trypsin domainPFAMPF00089Trypsincoord: 115..390
e-value: 3.3E-37
score: 128.5
IPR001254Serine proteases, trypsin domainPROSITEPS50240TRYPSIN_DOMcoord: 115..395
score: 25.289
IPR001254Serine proteases, trypsin domainCDDcd00190Tryp_SPccoord: 115..392
e-value: 1.16862E-49
score: 165.527
NoneNo IPR availableGENE3DG3DSA:2.40.10.10coord: 127..390
e-value: 1.3E-49
score: 170.8
NoneNo IPR availableGENE3DG3DSA:2.40.10.10coord: 117..384
e-value: 1.3E-49
score: 170.8
NoneNo IPR availablePANTHERPTHR24256:SF497coord: 4..395
NoneNo IPR availablePANTHERPTHR24256TRANSMEMBRANE PROTEASE, SERINEcoord: 4..395
IPR018114Serine proteases, trypsin family, histidine active sitePROSITEPS00134TRYPSIN_HIScoord: 155..160
IPR009003Peptidase S1, PA clanSUPERFAMILYSSF50494Trypsin-like serine proteasescoord: 96..395