40S ribosomal protein S12
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031089 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of 40S ribosomal protein S12 vs. Ensembl Human
Match: RPS12 (ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10385]) HSP 1 Score: 111.309 bits (277), Expect = 1.844e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Celegans
Match: rps-12 (40S ribosomal protein S12 [Source:UniProtKB/Swiss-Prot;Acc:P49196]) HSP 1 Score: 109.383 bits (272), Expect = 4.313e-31 Identity = 50/103 (48.54%), Postives = 69/103 (66.99%), Query Frame = 2 Query: 89 DSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNN 397 + +++VL+ A GL G+H+T KAL+ ++A C+LA+NCD+ Y KL+E LC EH IPL+KV K +GEY GLCK DK+ RK V CSS V++N N Sbjct: 23 EGALRAVLRAAHHADGLAKGLHETCKALDKREAHFCVLAENCDEPQYVKLVETLCAEHQIPLIKVADKKIIGEYCGLCKYDKEGKARKVVGCSSAVVTNWGNE 125
BLAST of 40S ribosomal protein S12 vs. Ensembl Celegans
Match: rps-12 (40S ribosomal protein S12 [Source:UniProtKB/Swiss-Prot;Acc:P49196]) HSP 1 Score: 109.383 bits (272), Expect = 4.313e-31 Identity = 50/103 (48.54%), Postives = 69/103 (66.99%), Query Frame = 2 Query: 89 DSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNN 397 + +++VL+ A GL G+H+T KAL+ ++A C+LA+NCD+ Y KL+E LC EH IPL+KV K +GEY GLCK DK+ RK V CSS V++N N Sbjct: 23 EGALRAVLRAAHHADGLAKGLHETCKALDKREAHFCVLAENCDEPQYVKLVETLCAEHQIPLIKVADKKIIGEYCGLCKYDKEGKARKVVGCSSAVVTNWGNE 125
BLAST of 40S ribosomal protein S12 vs. Ensembl Celegans
Match: rps-12 (40S ribosomal protein S12 [Source:UniProtKB/Swiss-Prot;Acc:P49196]) HSP 1 Score: 109.383 bits (272), Expect = 4.313e-31 Identity = 50/103 (48.54%), Postives = 69/103 (66.99%), Query Frame = 2 Query: 89 DSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNN 397 + +++VL+ A GL G+H+T KAL+ ++A C+LA+NCD+ Y KL+E LC EH IPL+KV K +GEY GLCK DK+ RK V CSS V++N N Sbjct: 23 EGALRAVLRAAHHADGLAKGLHETCKALDKREAHFCVLAENCDEPQYVKLVETLCAEHQIPLIKVADKKIIGEYCGLCKYDKEGKARKVVGCSSAVVTNWGNE 125
BLAST of 40S ribosomal protein S12 vs. Ensembl Celegans
Match: rps-12 (40S ribosomal protein S12 [Source:UniProtKB/Swiss-Prot;Acc:P49196]) HSP 1 Score: 109.383 bits (272), Expect = 4.313e-31 Identity = 50/103 (48.54%), Postives = 69/103 (66.99%), Query Frame = 2 Query: 89 DSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNN 397 + +++VL+ A GL G+H+T KAL+ ++A C+LA+NCD+ Y KL+E LC EH IPL+KV K +GEY GLCK DK+ RK V CSS V++N N Sbjct: 23 EGALRAVLRAAHHADGLAKGLHETCKALDKREAHFCVLAENCDEPQYVKLVETLCAEHQIPLIKVADKKIIGEYCGLCKYDKEGKARKVVGCSSAVVTNWGNE 125
BLAST of 40S ribosomal protein S12 vs. Ensembl Fly
Match: RpS12 (gene:FBgn0286213 transcript:FBtr0075878) HSP 1 Score: 114.39 bits (285), Expect = 6.067e-33 Identity = 53/101 (52.48%), Postives = 75/101 (74.26%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNI 388 +++ +Q VLK ++ GL GIHQ KAL+ ++A+LCILA++ D+ NY KL+ LC EH IPL++VDS+KKLGE++GLCK+DK+ PRK CS VVI + Sbjct: 21 INTALQEVLKKSLIADGLVHGIHQACKALDKRQAVLCILAESFDEPNYKKLVTALCNEHQIPLIRVDSHKKLGEWSGLCKIDKEGKPRKVCGCSVVVIKDF 121
BLAST of 40S ribosomal protein S12 vs. Ensembl Zebrafish
Match: rps12 (ribosomal protein S12 [Source:ZFIN;Acc:ZDB-GENE-030131-8951]) HSP 1 Score: 109.383 bits (272), Expect = 5.425e-31 Identity = 53/100 (53.00%), Postives = 70/100 (70.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ + VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VVI + Sbjct: 14 VNTALPEVLKTALIHDGLARGIREAAKALDKRQAHLCVLAANCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVIKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Zebrafish
Match: rps12 (ribosomal protein S12 [Source:ZFIN;Acc:ZDB-GENE-030131-8951]) HSP 1 Score: 109.383 bits (272), Expect = 5.425e-31 Identity = 53/100 (53.00%), Postives = 70/100 (70.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ + VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VVI + Sbjct: 14 VNTALPEVLKTALIHDGLARGIREAAKALDKRQAHLCVLAANCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVIKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Zebrafish
Match: rps12 (ribosomal protein S12 [Source:ZFIN;Acc:ZDB-GENE-030131-8951]) HSP 1 Score: 109.383 bits (272), Expect = 5.425e-31 Identity = 53/100 (53.00%), Postives = 70/100 (70.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ + VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VVI + Sbjct: 14 VNTALPEVLKTALIHDGLARGIREAAKALDKRQAHLCVLAANCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVIKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Xenopus
Match: rps12 (ribosomal protein S12 [Source:NCBI gene;Acc:493270]) HSP 1 Score: 111.309 bits (277), Expect = 1.374e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Xenopus
Match: rps12 (ribosomal protein S12 [Source:NCBI gene;Acc:493270]) HSP 1 Score: 110.923 bits (276), Expect = 1.767e-31 Identity = 53/98 (54.08%), Postives = 70/98 (71.43%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVI 379 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVV 111
BLAST of 40S ribosomal protein S12 vs. Ensembl Mouse
Match: Rps12 (ribosomal protein S12 [Source:MGI Symbol;Acc:MGI:98105]) HSP 1 Score: 111.309 bits (277), Expect = 1.266e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Mouse
Match: Rps12 (ribosomal protein S12 [Source:MGI Symbol;Acc:MGI:98105]) HSP 1 Score: 111.309 bits (277), Expect = 1.266e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Mouse
Match: Rps12 (ribosomal protein S12 [Source:MGI Symbol;Acc:MGI:98105]) HSP 1 Score: 110.923 bits (276), Expect = 2.792e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 30 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 129
BLAST of 40S ribosomal protein S12 vs. Ensembl Mouse
Match: Rps12 (ribosomal protein S12 [Source:MGI Symbol;Acc:MGI:98105]) HSP 1 Score: 105.145 bits (261), Expect = 3.820e-29 Identity = 53/105 (50.48%), Postives = 71/105 (67.62%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALE-----SQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKKPRKRRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 118
BLAST of 40S ribosomal protein S12 vs. UniProt/SwissProt
Match: sp|Q54PX9|RS12_DICDI (40S ribosomal protein S12 OS=Dictyostelium discoideum OX=44689 GN=rps12 PE=1 SV=1) HSP 1 Score: 127.872 bits (320), Expect = 3.345e-37 Identity = 59/123 (47.97%), Postives = 88/123 (71.54%), Query Frame = 2 Query: 77 EKSVDSLV--QSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ 439 EK+ D +V Q V+K++++V+G+ G+H+T KAL+ + A LC+LA NCD+ N+ +L++ L EHNIPL++V NK LGE+AGLCKLDKDL RK V+CS++VI +++ LM + KQ Sbjct: 14 EKNTDPMVALQKVIKESLAVQGVARGLHETVKALDKRTARLCVLASNCDEPNFVRLVKALATEHNIPLIEVPDNKALGEWAGLCKLDKDLAARKVVACSTLVIKTFGKESDDYKFLMEYISKQ 136
BLAST of 40S ribosomal protein S12 vs. UniProt/SwissProt
Match: sp|P80455|RS12_DROME (40S ribosomal protein S12 OS=Drosophila melanogaster OX=7227 GN=RpS12 PE=1 SV=2) HSP 1 Score: 114.39 bits (285), Expect = 6.081e-32 Identity = 53/101 (52.48%), Postives = 75/101 (74.26%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNI 388 +++ +Q VLK ++ GL GIHQ KAL+ ++A+LCILA++ D+ NY KL+ LC EH IPL++VDS+KKLGE++GLCK+DK+ PRK CS VVI + Sbjct: 21 INTALQEVLKKSLIADGLVHGIHQACKALDKRQAVLCILAESFDEPNYKKLVTALCNEHQIPLIRVDSHKKLGEWSGLCKIDKEGKPRKVCGCSVVVIKDF 121
BLAST of 40S ribosomal protein S12 vs. UniProt/SwissProt
Match: sp|P46405|RS12_PIG (40S ribosomal protein S12 OS=Sus scrofa OX=9823 GN=RPS12 PE=1 SV=2) HSP 1 Score: 111.309 bits (277), Expect = 8.853e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. UniProt/SwissProt
Match: sp|P25398|RS12_HUMAN (40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3) HSP 1 Score: 111.309 bits (277), Expect = 8.853e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. UniProt/SwissProt
Match: sp|Q76I81|RS12_BOVIN (40S ribosomal protein S12 OS=Bos taurus OX=9913 GN=RPS12 PE=2 SV=1) HSP 1 Score: 111.309 bits (277), Expect = 8.853e-31 Identity = 53/100 (53.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. TrEMBL
Match: C1C384 (40S ribosomal protein S12 OS=Caligus clemensi OX=344056 GN=RS12 PE=2 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 8.082e-35 Identity = 58/96 (60.42%), Postives = 76/96 (79.17%), Query Frame = 2 Query: 98 VQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 +Q VLK+A+ GL+ G+H+TTKAL+ ++AL C+LA+NCD+ Y KLI+ LC +H IPL+KVDSN KLGE+AGLCKLD D NPRK CSSVV+ + Sbjct: 31 IQEVLKEALIHNGLSRGLHETTKALDKRQALFCVLAENCDEPMYVKLIQALCAQHQIPLIKVDSNMKLGEWAGLCKLDSDGNPRKVTRCSSVVVRD 126
BLAST of 40S ribosomal protein S12 vs. TrEMBL
Match: D3PFR6 (40S ribosomal protein S12 OS=Lepeophtheirus salmonis OX=72036 GN=RS12 PE=2 SV=1) HSP 1 Score: 124.405 bits (311), Expect = 2.427e-33 Identity = 55/96 (57.29%), Postives = 75/96 (78.12%), Query Frame = 2 Query: 98 VQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 +Q VL++A+ GL+ G+ +TTKAL+ ++AL C+LA+NCD+ Y KL++ LC +H IPL+KVDSN KLGE+AGLCKLD D NPRK CSSVV+ + Sbjct: 29 IQEVLREALIHNGLSRGLRETTKALDKRQALFCVLAENCDEPMYVKLVQALCAQHQIPLIKVDSNMKLGEWAGLCKLDSDGNPRKVTRCSSVVVRD 124
BLAST of 40S ribosomal protein S12 vs. TrEMBL
Match: D1LYL9 (40S ribosomal protein S12 OS=Manduca sexta OX=7130 GN=rps12 PE=2 SV=1) HSP 1 Score: 124.02 bits (310), Expect = 3.239e-33 Identity = 60/116 (51.72%), Postives = 82/116 (70.69%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVK 433 V++ +Q VLK A+ GL G+H+ KAL+ ++A+LC+LA+NCD+A Y KL++ LC EH IPL+KVD+NKKLGE+AGLCK+DKD PRK V CS VVI + + L +K Sbjct: 21 VNTALQEVLKTALIHGGLVHGLHEAAKALDKRQAVLCVLAENCDEAAYKKLVQALCNEHQIPLVKVDNNKKLGEWAGLCKIDKDGKPRKIVGCSCVVIKDFGEETPALDVLKDYLK 136
BLAST of 40S ribosomal protein S12 vs. TrEMBL
Match: A0A4S2LVC3 (40S ribosomal protein S12 OS=Opisthorchis felineus OX=147828 GN=CRM22_004608 PE=3 SV=1) HSP 1 Score: 123.25 bits (308), Expect = 4.267e-33 Identity = 60/123 (48.78%), Postives = 82/123 (66.67%), Query Frame = 2 Query: 65 MMTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVK 433 M E +DS VQ VLK+A RG+ G+H+ +KA+E +KA+ C LA+NC+D Y+ LIE LC+EH IPL+KV NKKLGE AGLCK DK+ RK VS S +V+ +I W+ L+ + + Sbjct: 1 MNLNELDLDSAVQQVLKNAAKCRGIFRGLHECSKAIEQRKAVCCFLAENCNDKAYSCLIEALCREHEIPLIKVADNKKLGELAGLCKYDKEGKARKVVSASCIVVRDIGEESYGWKYLVEKYR 123
BLAST of 40S ribosomal protein S12 vs. TrEMBL
Match: A0A1S8WP26 (40S ribosomal protein S12 OS=Opisthorchis viverrini OX=6198 GN=X801_08036 PE=3 SV=1) HSP 1 Score: 123.25 bits (308), Expect = 4.267e-33 Identity = 60/123 (48.78%), Postives = 82/123 (66.67%), Query Frame = 2 Query: 65 MMTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVK 433 M E +DS VQ VLK+A RG+ G+H+ +KA+E +KA+ C LA+NC+D Y+ LIE LC+EH IPL+KV NKKLGE AGLCK DK+ RK VS S +V+ +I W+ L+ + + Sbjct: 1 MNLNELDLDSAVQQVLKNAAKCRGIFRGLHECSKAIEQRKAVCCFLAENCNDKAYSCLIEALCREHEIPLIKVADNKKLGELAGLCKYDKEGKARKVVSASCIVVRDIGEESYGWKYLVEKYR 123
BLAST of 40S ribosomal protein S12 vs. Ensembl Cavefish
Match: rps12 (ribosomal protein S12 [Source:NCBI gene;Acc:103033124]) HSP 1 Score: 109.383 bits (272), Expect = 4.597e-31 Identity = 53/100 (53.00%), Postives = 70/100 (70.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ + VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VVI + Sbjct: 14 VNTALPEVLKTALIHDGLARGIREAAKALDKRQAHLCVLAANCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVIKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005589.1 (pep scaffold:Pmarinus_7.0:GL480041:19082:24249:-1 gene:ENSPMAG00000005068.1 transcript:ENSPMAT00000005589.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 109.768 bits (273), Expect = 6.908e-32 Identity = 52/100 (52.00%), Postives = 71/100 (71.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ +Q VLK A+ GL G+ + KAL+ + A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE++GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALQEVLKTALIHDGLARGLREAAKALDKRHAHLCVLASNCDEPMYVKLVEALCNEHQINLIKVDDNKKLGEWSGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. Ensembl Yeast
Match: RPS12 (Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S12, no bacterial homolog [Source:SGD;Acc:S000005896]) HSP 1 Score: 72.0182 bits (175), Expect = 3.115e-17 Identity = 38/94 (40.43%), Postives = 61/94 (64.89%), Query Frame = 2 Query: 77 EKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCK--EHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRK 352 E +++ ++ VL+ A+ GL G+ ++TKAL +ALL +L + +AN KL+E L E+ +PL+KV K+LGE+AGL K+D++ N RK Sbjct: 21 EVTIEDALKVVLRTALVHDGLARGLRESTKALTRGEALLVVLVSSVTEANIIKLVEGLANDPENKVPLIKVADAKQLGEWAGLGKIDREGNARK 114
BLAST of 40S ribosomal protein S12 vs. Ensembl Nematostella
Match: EDO35867 (40S ribosomal protein S12 [Source:UniProtKB/TrEMBL;Acc:A7SK96]) HSP 1 Score: 120.553 bits (301), Expect = 1.189e-35 Identity = 58/118 (49.15%), Postives = 83/118 (70.34%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ 439 +++ +Q VLK A+ GL+ G+H+ K+L+ ++A LCIL+ NCD+A Y KL+E LC EH IPLLKVD +KKLGE+AGLCK+DK+ RK V CS VV+ +I + + LM +K + Sbjct: 21 INTALQEVLKTALIHDGLSRGLHEAAKSLDKREAHLCILSNNCDEAMYVKLVEALCAEHGIPLLKVDDSKKLGEWAGLCKIDKEGKARKVVGCSCVVVKDIGKDSQAHDVLMQYLKSK 138
BLAST of 40S ribosomal protein S12 vs. Ensembl Medaka
Match: rps12 (ribosomal protein S12 [Source:NCBI gene;Acc:101172123]) HSP 1 Score: 108.997 bits (271), Expect = 8.766e-31 Identity = 52/100 (52.00%), Postives = 70/100 (70.00%), Query Frame = 2 Query: 86 VDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISN 385 V++ + VLK A+ GL GI + KAL+ ++A LC+LA NCD+ Y KL+E LC EH I L+KVD NKKLGE+ GLCK+D++ PRK V CS VV+ + Sbjct: 14 VNTALPEVLKTALIHDGLARGIREAAKALDKRQAHLCVLAANCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKD 113
BLAST of 40S ribosomal protein S12 vs. Planmine SMEST
Match: SMESG000052688.1 (SMESG000052688.1) HSP 1 Score: 252.292 bits (643), Expect = 1.469e-87 Identity = 125/125 (100.00%), Postives = 125/125 (100.00%), Query Frame = 2 Query: 65 MMTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ 439 MMTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ Sbjct: 1 MMTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ 125
BLAST of 40S ribosomal protein S12 vs. Planmine SMEST
Match: SMESG000052688.1 (SMESG000052688.1) HSP 1 Score: 249.595 bits (636), Expect = 1.346e-86 Identity = 124/124 (100.00%), Postives = 124/124 (100.00%), Query Frame = 2 Query: 68 MTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ 439 MTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ Sbjct: 1 MTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEVKKQ 124
BLAST of 40S ribosomal protein S12 vs. Planmine SMEST
Match: SMESG000069457.1 (SMESG000069457.1) HSP 1 Score: 76.6406 bits (187), Expect = 2.048e-18 Identity = 40/116 (34.48%), Postives = 67/116 (57.76%), Query Frame = 2 Query: 83 SVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCDDANYTKLIEVLCKEHNIPLLKVDSNKKLGEYAGLCKLDKDLNPRKTVSCSSVVISNIPNNCTNWEALMSEV 430 ++DS + V A ++ L G+ + K+LE Q A+LC+ A + ++ LI+ LC +N+P + S +LGE +GL +LD+D N RK VS S V++ + +C W+ + S V Sbjct: 2 NLDSALSDVFHRAFALNILCRGLKECVKSLERQTAVLCVGADDTEERAIISLIQSLCVNNNVPFIHFPSKYRLGEISGLRRLDEDGNSRKVVSTSVVIVKDQIIDCEGWQYINSNV 117 The following BLAST results are available for this feature:
BLAST of 40S ribosomal protein S12 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 1
BLAST of 40S ribosomal protein S12 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 4
BLAST of 40S ribosomal protein S12 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of 40S ribosomal protein S12 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of 40S ribosomal protein S12 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of 40S ribosomal protein S12 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of 40S ribosomal protein S12 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of 40S ribosomal protein S12 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of 40S ribosomal protein S12 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of 40S ribosomal protein S12 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of 40S ribosomal protein S12 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of 40S ribosomal protein S12 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of 40S ribosomal protein S12 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of 40S ribosomal protein S12 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031089 ID=SMED30031089|Name=40S ribosomal protein S12|organism=Schmidtea mediterranea sexual|type=transcript|length=491bpback to top protein sequence of SMED30031089-orf-1 >SMED30031089-orf-1 ID=SMED30031089-orf-1|Name=SMED30031089-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=126bp MMTEEKSVDSLVQSVLKDAVSVRGLTCGIHQTTKALESQKALLCILAKNCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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