Galanin receptor type 2

Overview
NameGalanin receptor type 2
Smed IDSMED30031058
Length (bp)1722
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Galanin receptor type 2 (SMED30031058) t-SNE clustered cells

Violin plots show distribution of expression levels for Galanin receptor type 2 (SMED30031058) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Galanin receptor type 2 (SMED30031058) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Galanin receptor type 2 (SMED30031058) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30031058

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 14

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30031058h1SMcG0022757 dd_Smed_v4_18897_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30031058h1SMcG0022757 dd_Smed_v6_18897_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30031058h1SMcG0022757 dd_Smed_v6_18897_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30031058h1SMcG0022757 Contig36679uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30031058h1SMcG0022757 Contig36679newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30031058h1SMcG0022757 Contig36679uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30031058h1SMcG0022757 Contig36679newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Galanin receptor type 2 vs. Ensembl Human
Match: GALR2 (galanin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4133])

HSP 1 Score: 84.7297 bits (208), Expect = 6.023e-17
Identity = 60/282 (21.28%), Postives = 124/282 (43.97%), Query Frame = 1
Query:  439 DYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQ--LVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSS 1278
            D + F  +LC  VHF++++ + +S+  L  +++ R+LA+ +P  +R                        + + +G+  +    G           Q  ++  C   +     R +  I  F+ +YLLP + + L     +R L   V+     S                     R+ + +VT+M+++V+ L+C+CW+P    ++ VW+     +FP  R    ++ +S  +S+A++C+NPIVY++V++ F+   +  C  L   A    S  +  + + +
Sbjct:   89 DGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSR-------------ELRTPRNALAAIGLIWGLSLL--FSGPYLSYYRQS--QLANLTVCHPAWSAPRRRAMD-ICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGA-------------------RRAKRKVTRMILIVAALFCLCWMPHHALILCVWF----GQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGT 329          
BLAST of Galanin receptor type 2 vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 67.3958 bits (163), Expect = 2.971e-11
Identity = 72/295 (24.41%), Postives = 134/295 (45.42%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILM-NYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQ----YVKFISQTLSFASTCINPIVYSVVNETFKIAVKK--QCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKT 1314
            F + +C I   +  +++ +S   L+ + V RF  VV+P++ ++       I   I  +     S P A+   V++    +  LN   +T     + +  C++ +PNQ  R IY  ++F   YL P   I++M   + +   R  V          G+      H+ S    RK+Q   ++ KM+++V+ L+ + WLP  L  +   +D      N  +Q    Y+   +  L+F ++ +NPI+Y   NE F+   ++  Q     + AKP  +   +K+    L+  S QLV ++
Sbjct:  113 FGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMS-PSAVMLHVQEEKYYRVRLNSQNKT-----SPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPH-------TGRKNQEQWHVVS----RKKQ---KIIKMLLIVALLFILSWLP--LWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAY-ALKAKSHVLINTSNQLVQES 383          
BLAST of Galanin receptor type 2 vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 67.781 bits (164), Expect = 2.987e-11
Identity = 72/295 (24.41%), Postives = 134/295 (45.42%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILM-NYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQ----YVKFISQTLSFASTCINPIVYSVVNETFKIAVKK--QCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKT 1314
            F + +C I   +  +++ +S   L+ + V RF  VV+P++ ++       I   I  +     S P A+   V++    +  LN   +T     + +  C++ +PNQ  R IY  ++F   YL P   I++M   + +   R  V          G+      H+ S    RK+Q   ++ KM+++V+ L+ + WLP  L  +   +D      N  +Q    Y+   +  L+F ++ +NPI+Y   NE F+   ++  Q     + AKP  +   +K+    L+  S QLV ++
Sbjct:  215 FGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMS-PSAVMLHVQEEKYYRVRLNSQNKT-----SPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPH-------TGRKNQEQWHVVS----RKKQ---KIIKMLLIVALLFILSWLP--LWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAY-ALKAKSHVLINTSNQLVQES 485          
BLAST of Galanin receptor type 2 vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 67.0106 bits (162), Expect = 3.462e-11
Identity = 72/295 (24.41%), Postives = 134/295 (45.42%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILM-NYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQ----YVKFISQTLSFASTCINPIVYSVVNETFKIAVKK--QCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKT 1314
            F + +C I   +  +++ +S   L+ + V RF  VV+P++ ++       I   I  +     S P A+   V++    +  LN   +T     + +  C++ +PNQ  R IY  ++F   YL P   I++M   + +   R  V          G+      H+ S    RK+Q   ++ KM+++V+ L+ + WLP  L  +   +D      N  +Q    Y+   +  L+F ++ +NPI+Y   NE F+   ++  Q     + AKP  +   +K+    L+  S QLV ++
Sbjct:  116 FGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMS-PSAVMLHVQEEKYYRVRLNSQNKT-----SPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPH-------TGRKNQEQWHVVS----RKKQ---KIIKMLLIVALLFILSWLP--LWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAY-ALKAKSHVLINTSNQLVQES 386          
BLAST of Galanin receptor type 2 vs. Ensembl Human
Match: SSTR5 (somatostatin receptor 5 [Source:HGNC Symbol;Acc:HGNC:11334])

HSP 1 Score: 63.5438 bits (153), Expect = 3.281e-10
Identity = 70/260 (26.92%), Postives = 122/260 (46.92%), Query Frame = 1
Query:  430 SSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQN-RMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKK 1206
            ++  ++ F  VLC +V  +  V  F+S   L  ++V R+LAVVHP  + R    + AK+A   AW++  C S+P+ ++  V++     GT N +    WP+   +              ++ I   +L +  P + I L   LIV K+R            VG         C    +R+R  R +VT+MV++V  ++  CWLP   VN+         P+      + F    LS+A++C NP++Y  +++ F+ + +K
Sbjct:  100 NAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQE----GGTCNAS----WPEPVGLWG-----------AVFIIYTAVLGFFAPLLVICLCYLLIVVKVR-------AAGVRVG---------C----VRRRSER-KVTRMVLVVVLVFAGCWLPFFTVNIVNLA--VALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQK 317          
BLAST of Galanin receptor type 2 vs. Ensembl Celegans
Match: npr-6 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q20275])

HSP 1 Score: 61.6178 bits (148), Expect = 5.887e-10
Identity = 42/179 (23.46%), Postives = 84/179 (46.93%), Query Frame = 1
Query:  748 CKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSSLL 1284
            C + + N   R+I+ I+V +L ++LPF+ +I ++Y+ +    N      E+   + + K                   R+ +M+I++  ++ +CW P  L+N         F +     +V      +S  +T  NPI+Y+ +NETF+    K  PCLF   +P    I + + +++++
Sbjct:  193 CSEDWSNAEFRSIFGIVVMILQFILPFV-LIAISYIKIWLFLNSRQSMTERKSDIKRKK-------------------RLLRMLIVMVVIFAICWFPFNLLNCLRDLKLDNFMRGY-FSFVFLSVHLMSMTATAWNPILYAFMNETFREEFAKVVPCLF-ARRPGTGPIRVITERTAMI 349          
BLAST of Galanin receptor type 2 vs. Ensembl Celegans
Match: trhr-1 (Thyrotropin-Releasing Hormone Receptor [Source:UniProtKB/TrEMBL;Acc:Q95YD7])

HSP 1 Score: 60.8474 bits (146), Expect = 1.020e-9
Identity = 66/279 (23.66%), Postives = 123/279 (44.09%), Query Frame = 1
Query:  436 QDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGT----LNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIV---------------RKLRNEVNQDYEK--SDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVW--YYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVK 1203
             D++ F  + C ++ ++ Y+A+ +S+  +L  T+ R+  + +P++ R                          I  G+   + +  +    L   ++ D     S +    L  N +   I F+L F+L Y+LP M  I++   I                 K+ NEV  +  K  S ++G       HI   R   K   RN+V KM+ +V  ++ VCWLP + + V+  + +DPK    +    +   +S+TL F +  INPI+Y++++  F+ A +
Sbjct:   97 NDHYLFGSLGCVLLTYLPYLAMNTSSLSILAFTIERYYGICNPYKAR----------------TMCTVKRATCIICGIWIFSMLYHSYWLFLATLIKDDIGTSCSFR----LERNSHAYKIVFLLDFVLWYVLPIMCDIIIYAKIGITLSQCGDKIKKSVKPKIPNEVIVEKSKTSSTSMGHYSGRDSHISGKRNSAKG--RNQVVKMLAIVVAVFAVCWLPYRGMVVYNSFVSDPKY---SWSPDWYINLSKTLVFINCAINPILYNLMSARFRAAFR 350          
BLAST of Galanin receptor type 2 vs. Ensembl Celegans
Match: npr-9 (Galanin-like G-protein coupled receptor npr-9 [Source:UniProtKB/Swiss-Prot;Acc:Q23497])

HSP 1 Score: 56.225 bits (134), Expect = 4.145e-8
Identity = 38/142 (26.76%), Postives = 75/142 (52.82%), Query Frame = 1
Query:  787 YFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKR----QVRNRVTKMVILVSTLYCVCWLPTQL---VNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFK 1191
            YF+   +  Y+LP    +++  L++RKL +        S +VG   L +    S   IR+R      + +VT++V+ V   + +CWLP  +   ++   Y +P        M  V+  SQ L++ ++C+NPI+Y++++++F+
Sbjct:  214 YFMTFNVFGYVLPLGISVVLYGLMLRKLWDMPRPG--NSQSVGGRNLTNRD--SGSSIRRRPEATAAKRKVTRLVLCVLITWALCWLPLNVCFFMSGLAYPEPLVISHGVIMVIVQIASQVLAYTNSCLNPILYALMSQSFR 351          
BLAST of Galanin receptor type 2 vs. Ensembl Celegans
Match: npr-12 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:V6CLI1])

HSP 1 Score: 48.521 bits (114), Expect = 8.551e-6
Identity = 34/144 (23.61%), Postives = 67/144 (46.53%), Query Frame = 1
Query:  775 NRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKK 1206
            ++T Y  +V  + Y+LP  ++    + I                T+ K   +S  + +TR ++ +    R   ++ L+   Y VCW P  + +V    +   + +N     +      +  +STC+NPIVY++VNE+F+ A++ 
Sbjct:  215 SKTTYTFVVLGIQYILPLAALAYAYFQI--------------GSTIQKRSKVSRTVDTTRRMQMQNRNRRALLLLFLLVLTYAVCWAPMNIYHVLNGLEIINYSQN-----MYIFCHLVGISSTCVNPIVYALVNESFRNALQS 339          
BLAST of Galanin receptor type 2 vs. Ensembl Celegans
Match: npr-12 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:V6CLI1])

HSP 1 Score: 48.521 bits (114), Expect = 8.737e-6
Identity = 34/144 (23.61%), Postives = 67/144 (46.53%), Query Frame = 1
Query:  775 NRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKK 1206
            ++T Y  +V  + Y+LP  ++    + I                T+ K   +S  + +TR ++ +    R   ++ L+   Y VCW P  + +V    +   + +N     +      +  +STC+NPIVY++VNE+F+ A++ 
Sbjct:  221 SKTTYTFVVLGIQYILPLAALAYAYFQI--------------GSTIQKRSKVSRTVDTTRRMQMQNRNRRALLLLFLLVLTYAVCWAPMNIYHVLNGLEIINYSQN-----MYIFCHLVGISSTCVNPIVYALVNESFRNALQS 345          
BLAST of Galanin receptor type 2 vs. Ensembl Fly
Match: TkR99D (gene:FBgn0004622 transcript:FBtr0301656)

HSP 1 Score: 69.707 bits (169), Expect = 2.906e-12
Identity = 59/257 (22.96%), Postives = 118/257 (45.91%), Query Frame = 1
Query:  445 FQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTL-ETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQT---LSFASTCINPIVYSVVNETFKIAVK 1203
            + F +  C +  FI  +++ +S   L+ +++ R++A++ P Q RM       IA  I          P+ I +  E++  V+G  N+T+   +WP   +     +        ++Y IL+ +LTY LP +S+ +          + V  +   S T+G+        C+ R++   + + RV KM+I+V  ++ +CWLP       Y+     +P      +++ +      L+ +++  NPI+Y  +N  F+   K
Sbjct:  167 WPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISC-PMMIIYRTEEV-PVRGLSNRTVCYPEWPDGPTNHSTME--------SLYNILIIILTYFLPIVSMTVT--------YSRVGIELWGSKTIGE--------CTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHS----YFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFK 393          
BLAST of Galanin receptor type 2 vs. Ensembl Fly
Match: TkR99D (gene:FBgn0004622 transcript:FBtr0085507)

HSP 1 Score: 69.707 bits (169), Expect = 3.023e-12
Identity = 59/257 (22.96%), Postives = 118/257 (45.91%), Query Frame = 1
Query:  445 FQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTL-ETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQT---LSFASTCINPIVYSVVNETFKIAVK 1203
            + F +  C +  FI  +++ +S   L+ +++ R++A++ P Q RM       IA  I          P+ I +  E++  V+G  N+T+   +WP   +     +        ++Y IL+ +LTY LP +S+ +          + V  +   S T+G+        C+ R++   + + RV KM+I+V  ++ +CWLP       Y+     +P      +++ +      L+ +++  NPI+Y  +N  F+   K
Sbjct:  167 WPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISC-PMMIIYRTEEV-PVRGLSNRTVCYPEWPDGPTNHSTME--------SLYNILIIILTYFLPIVSMTVT--------YSRVGIELWGSKTIGE--------CTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHS----YFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFK 393          
BLAST of Galanin receptor type 2 vs. Ensembl Fly
Match: TkR99D (gene:FBgn0004622 transcript:FBtr0330298)

HSP 1 Score: 69.3218 bits (168), Expect = 4.271e-12
Identity = 59/257 (22.96%), Postives = 118/257 (45.91%), Query Frame = 1
Query:  445 FQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTL-ETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQT---LSFASTCINPIVYSVVNETFKIAVK 1203
            + F +  C +  FI  +++ +S   L+ +++ R++A++ P Q RM       IA  I          P+ I +  E++  V+G  N+T+   +WP   +     +        ++Y IL+ +LTY LP +S+ +          + V  +   S T+G+        C+ R++   + + RV KM+I+V  ++ +CWLP       Y+     +P      +++ +      L+ +++  NPI+Y  +N  F+   K
Sbjct:  167 WPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISC-PMMIIYRTEEV-PVRGLSNRTVCYPEWPDGPTNHSTME--------SLYNILIIILTYFLPIVSMTVT--------YSRVGIELWGSKTIGE--------CTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHS----YFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFK 393          
BLAST of Galanin receptor type 2 vs. Ensembl Fly
Match: AstC-R1 (gene:FBgn0036790 transcript:FBtr0089578)

HSP 1 Score: 65.4698 bits (158), Expect = 7.202e-11
Identity = 64/262 (24.43%), Postives = 124/262 (47.33%), Query Frame = 1
Query:  445 FQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQN-RMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVG-KPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCL 1221
            ++F + +C        +  F+S+  LL ++  R++AV HP  + R  +   AK+   IAW       +PV +Y       + +  +N +    WP  ++ KK        ++ T + +  F L +  P   I+   YL++RKLR           +VG KP         T+   KR+   +VT++V+ V ++Y +CWLP  +  V   +++P +   +R    +  +   L ++++ +NPI+Y+ ++E F+ +  K   C+
Sbjct:  142 WRFGEFMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVILY---ASTVEQEDGINYSCNIMWP--DAYKK--------HSGTTFILYTFFLGFATPLCFILSFYYLVIRKLR-----------SVGPKP--------GTKSKEKRRAHRKVTRLVLTVISVYILCWLPHWISQVALIHSNPAQRDLSRLEILIFLLLGALVYSNSAVNPILYAFLSENFRKSFFKAFTCM 371          
BLAST of Galanin receptor type 2 vs. Ensembl Fly
Match: sNPF-R (gene:FBgn0036934 transcript:FBtr0332667)

HSP 1 Score: 63.5438 bits (153), Expect = 2.924e-10
Identity = 43/160 (26.88%), Postives = 75/160 (46.88%), Query Frame = 1
Query:  748 CKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKF--ISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCL 1221
            C++ +P++  R ++  +   L ++LPF  I +    I  KL               KP   S    S RE   R  + R  +M+I +  ++ + WLP  +VN++   D K    N    Y+ F  ++ +++ +STC NP +Y+ +NE F+   K   PC 
Sbjct:  268 CEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRAR---------AKPGSKS----SRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDK---SNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCF 411          
BLAST of Galanin receptor type 2 vs. Ensembl Zebrafish
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 90.8929 bits (224), Expect = 2.804e-19
Identity = 83/357 (23.25%), Postives = 163/357 (45.66%), Query Frame = 1
Query:  274 IIFIVGTLSNGCVIFILTR---VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFP--NQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLV--NVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR--------VAKPSPSVIIIKSNKSSLLKGSQQ 1299
            +IF+VGT+ N  V+ +L R   +  KS    I          I+  V    T++  + D + F   +C  VHFI+Y+ +++S   L  +++ R+LA+ +P ++R       +       +        ++++F    ++             + QQ  +       P  + ++R    I  F+  YL+P + + +     +R L   V+   + S++                   R+ + +VTKM+I+V+ L+C+CWLP  LV   +W+      FP N     ++ +S  +++A++C+NPIVY++V++ F+   KK   C FR          +P+ +V ++++  S   +GS  
Sbjct:   27 MIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIY--TMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSR-------ETRTPRNALTSISLVWALSLFFSSPYLS-------------YYQQMDLDGTTVCIPAWSVHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSES-------------------RKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWF----GHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGCAFRNRVVNRIHTVQPAQTVSLMEAASS---EGSNH 335          
BLAST of Galanin receptor type 2 vs. Ensembl Zebrafish
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 90.8929 bits (224), Expect = 2.804e-19
Identity = 83/357 (23.25%), Postives = 163/357 (45.66%), Query Frame = 1
Query:  274 IIFIVGTLSNGCVIFILTR---VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFP--NQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLV--NVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR--------VAKPSPSVIIIKSNKSSLLKGSQQ 1299
            +IF+VGT+ N  V+ +L R   +  KS    I          I+  V    T++  + D + F   +C  VHFI+Y+ +++S   L  +++ R+LA+ +P ++R       +       +        ++++F    ++             + QQ  +       P  + ++R    I  F+  YL+P + + +     +R L   V+   + S++                   R+ + +VTKM+I+V+ L+C+CWLP  LV   +W+      FP N     ++ +S  +++A++C+NPIVY++V++ F+   KK   C FR          +P+ +V ++++  S   +GS  
Sbjct:   27 MIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIY--TMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSR-------ETRTPRNALTSISLVWALSLFFSSPYLS-------------YYQQMDLDGTTVCIPAWSVHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSES-------------------RKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWF----GHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGCAFRNRVVNRIHTVQPAQTVSLMEAASS---EGSNH 335          
BLAST of Galanin receptor type 2 vs. Ensembl Zebrafish
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 90.5077 bits (223), Expect = 2.877e-19
Identity = 83/357 (23.25%), Postives = 163/357 (45.66%), Query Frame = 1
Query:  274 IIFIVGTLSNGCVIFILTR---VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFP--NQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLV--NVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR--------VAKPSPSVIIIKSNKSSLLKGSQQ 1299
            +IF+VGT+ N  V+ +L R   +  KS    I          I+  V    T++  + D + F   +C  VHFI+Y+ +++S   L  +++ R+LA+ +P ++R       +       +        ++++F    ++             + QQ  +       P  + ++R    I  F+  YL+P + + +     +R L   V+   + S++                   R+ + +VTKM+I+V+ L+C+CWLP  LV   +W+      FP N     ++ +S  +++A++C+NPIVY++V++ F+   KK   C FR          +P+ +V ++++  S   +GS  
Sbjct:   26 MIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIY--TMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSR-------ETRTPRNALTSISLVWALSLFFSSPYLS-------------YYQQMDLDGTTVCIPAWSVHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSES-------------------RKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWF----GHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGCAFRNRVVNRIHTVQPAQTVSLMEAASS---EGSNH 334          
BLAST of Galanin receptor type 2 vs. Ensembl Zebrafish
Match: galr2b (galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-131121-48])

HSP 1 Score: 81.6481 bits (200), Expect = 3.647e-16
Identity = 79/334 (23.65%), Postives = 151/334 (45.21%), Query Frame = 1
Query:  274 IIFIVGTLSNGCVIFILTR------------VENKSVYD----IICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCL 1221
            +IF++GT+ N  V+ +L R            + N SV D    I CV    T               YS + +  F   +C +VHF + + +++S+  L  ++V R+LA+ +P ++R + +   A +A  + W +    + P   Y+ + D        +      W               ++NR +     F+  Y++P + + L     ++ L   V+     S++                   ++ + +VTKM+I+V+ L+C+CWLP  +V + Y Y D   FP N+     + +S  +++A++C+NPIVY++V++ F+   KK   C+
Sbjct:   35 LIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATI--------------YSLEGWV-FGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSYYDLIDFEN-----SNVCVPGW--------------EEHNRKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSES-------------------KRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYGD---FPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCI 312          
BLAST of Galanin receptor type 2 vs. Ensembl Zebrafish
Match: galr2b (galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-131121-48])

HSP 1 Score: 81.6481 bits (200), Expect = 3.647e-16
Identity = 79/334 (23.65%), Postives = 151/334 (45.21%), Query Frame = 1
Query:  274 IIFIVGTLSNGCVIFILTR------------VENKSVYD----IICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCL 1221
            +IF++GT+ N  V+ +L R            + N SV D    I CV    T               YS + +  F   +C +VHF + + +++S+  L  ++V R+LA+ +P ++R + +   A +A  + W +    + P   Y+ + D        +      W               ++NR +     F+  Y++P + + L     ++ L   V+     S++                   ++ + +VTKM+I+V+ L+C+CWLP  +V + Y Y D   FP N+     + +S  +++A++C+NPIVY++V++ F+   KK   C+
Sbjct:   35 LIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATI--------------YSLEGWV-FGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSYYDLIDFEN-----SNVCVPGW--------------EEHNRKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSES-------------------KRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYGD---FPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCI 312          
BLAST of Galanin receptor type 2 vs. Ensembl Xenopus
Match: sp3 (Sp3 transcription factor [Source:Xenbase;Acc:XB-GENE-977158])

HSP 1 Score: 88.5817 bits (218), Expect = 2.390e-18
Identity = 66/269 (24.54%), Postives = 129/269 (47.96%), Query Frame = 1
Query:  427 YSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            YS +D+  F   +C  VHF +Y+ +++S+  L  ++V R+LA+ +P ++R + +   A     I W +    + P   Y+ + D        +      W ++               R I     F++ Y++P + + L     ++ L   V+   + S++                   ++ + +VTKM+I+V+ L+C+CWLP  +V + Y Y D   FP N+     + +S  +++A++C+NPIVY++V++ F+   +K   CL R
Sbjct:  111 YSLEDWV-FGAFMCKAVHFFIYLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAIATMAIIWGLSVVFAGPYLSYYDLMDYES-----SHICMPGWKERT--------------RKIMDTGTFIVGYVIPVLIVSLSYTRTIKYLWTAVDPLEDMSES-------------------KKAKRKVTKMIIIVTVLFCLCWLPHHVVVMCYLYGD---FPFNQATYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFQKVFSCLLR 337          
BLAST of Galanin receptor type 2 vs. Ensembl Xenopus
Match: sp3 (Sp3 transcription factor [Source:Xenbase;Acc:XB-GENE-977158])

HSP 1 Score: 88.1965 bits (217), Expect = 2.919e-18
Identity = 66/269 (24.54%), Postives = 129/269 (47.96%), Query Frame = 1
Query:  427 YSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            YS +D+  F   +C  VHF +Y+ +++S+  L  ++V R+LA+ +P ++R + +   A     I W +    + P   Y+ + D        +      W ++               R I     F++ Y++P + + L     ++ L   V+   + S++                   ++ + +VTKM+I+V+ L+C+CWLP  +V + Y Y D   FP N+     + +S  +++A++C+NPIVY++V++ F+   +K   CL R
Sbjct:   88 YSLEDWV-FGAFMCKAVHFFIYLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAIATMAIIWGLSVVFAGPYLSYYDLMDYES-----SHICMPGWKERT--------------RKIMDTGTFIVGYVIPVLIVSLSYTRTIKYLWTAVDPLEDMSES-------------------KKAKRKVTKMIIIVTVLFCLCWLPHHVVVMCYLYGD---FPFNQATYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFQKVFSCLLR 314          
BLAST of Galanin receptor type 2 vs. Ensembl Xenopus
Match: ENSXETT00000041298.1 (galanin receptor 3 [Source:NCBI gene;Acc:100488248])

HSP 1 Score: 85.8853 bits (211), Expect = 1.680e-17
Identity = 65/264 (24.62%), Postives = 123/264 (46.59%), Query Frame = 1
Query:  439 DYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNR--TIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLF 1224
            D + F   LC  VHF +Y+++++S+  L  ++V R+LA+ +P ++R        +      +        ++I F    ++     L           N +  C    PN  +R   I  +  F+  YLLP + + L     +  L   V+     S++                   R+ +++VTKM+I+V+ L+C+CWLP  LV + ++     FP N+     + +S  +S+A++C+NPIVY+++++ F+   K+   CL 
Sbjct:   82 DGWLFGAFLCKAVHFSIYLSMYASSFTLAAVSVDRYLAIRYPLKSR-------DLRTSRNALAAIGVIWALSILFAGPYLSYYHIIL----------YNQVPIC---IPNWEDRRRKIMDVSTFVFGYLLPVLILGLSYARTICFLWTSVDPVKTASES-------------------RKAKHKVTKMIIIVAVLFCICWLPHHLVILCFWFG--HFPFNKATYAFRLVSHCMSYANSCLNPIVYALISKHFRKRFKQVFTCLL 304          
BLAST of Galanin receptor type 2 vs. Ensembl Xenopus
Match: GALR2 (galanin receptor 2 [Source:NCBI gene;Acc:100486593])

HSP 1 Score: 85.1149 bits (209), Expect = 3.288e-17
Identity = 84/327 (25.69%), Postives = 160/327 (48.93%), Query Frame = 1
Query:  262 IFWVIIFIVGTLSNGCVIFILTR---VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLV--NVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLF 1224
            + + +IF+VGT+ N  V+ +L R   V N +   I+ +G+A    +I  V    T     + D + F   +C  VHF +Y+ +++S+  L T+++ R+LA+ +P ++R + + K A +A  + W +    S P   Y+    ++ +           W  Q+S ++  DL              F  +Y++P + + L     +R L   V+   + S++                   ++ + RVT+M+I+V+ L+C+CWLP  LV   VW+      FP N     ++ +S  +S+A++C+NP+VY++V++ F+   +K   CL 
Sbjct:   22 VLYSLIFLVGTVGNSLVLAVLLRNGKVNNTTNLFILNLGVADLCFIIFCVPFQATIY---TLDSWVFGPFMCKAVHFFIYLTMYASSFTLTTVSLDRYLAIRYPLRSRELRTPKNALLAITLIWSLSLVFSGPYLSYYQEFQLSNLT-----VCHPVW--QDSYRRAMDL------------CTFAFSYVIPVLILSLTYARTIRYLWTAVDPIEDMSES-------------------KRAKRRVTRMIIIVAVLFCLCWLPHHLVILCVWF----GYFPLNNFTYALRILSHLVSYANSCVNPVVYALVSKHFRKGFRKIFRCLL 303          
BLAST of Galanin receptor type 2 vs. Ensembl Xenopus
Match: kiss1r (KISS1 receptor [Source:NCBI gene;Acc:100316929])

HSP 1 Score: 73.1738 bits (178), Expect = 2.291e-13
Identity = 71/276 (25.72%), Postives = 127/276 (46.01%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQN-RMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDW--PQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSN 1269
            F + +C  V++I  V++ ++   L  ++V R+   V+P Q+ R  + + A       WI     SIPV IY             N+ +E  W  PQ      C + FP+ ++   + +  FL+ YLLP ++I +    +V ++        E  D   + +LL+         R   +R ++++MV ++  L+ +CW P QL  ++    P  F ++     VK  +  +S+ ++ INPIVY+ +   F+ A  K  P LF+    S  V    +N
Sbjct:  110 FGEFMCKFVNYIQQVSVQATCVTLTAMSVDRWYVTVYPLQSLRQRTPRVAAAVSVGIWIGSFIVSIPVPIY-------------NQLIEGYWFGPQ----IYCSESFPSVSHEKAFILYNFLVVYLLPLITICICYSAMVYQMGRP---SVEPVDNSYQVQLLAE--------RSELMRTKISRMVAVIVLLFTICWGPIQLYILFQAFSPS-FKRDYYTYKVKIWANCMSYTNSSINPIVYAFMGANFRKAFNKVFPFLFKQRVGSTGVANANAN 356          
BLAST of Galanin receptor type 2 vs. Ensembl Mouse
Match: Galr2 (galanin receptor 2 [Source:MGI Symbol;Acc:MGI:1337018])

HSP 1 Score: 87.4261 bits (215), Expect = 4.368e-18
Identity = 67/287 (23.34%), Postives = 133/287 (46.34%), Query Frame = 1
Query:  439 DYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDW--PQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQ--LVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVA--KPSPSVIIIKSNKSS 1278
            D + F  +LC  VHF++++ + +S+  L  +++ R+LA+ +P  +R + + + A  A  + W +    S P   Y+    +  +           W  P++ ++  C                 F+ +YLLP + + L     +  L   V+     S +                   ++ + +VT+M+++V+ L+C+CW+P    ++ VW+     RFP  R    ++ +S  +S+A++C+NPIVY++V++ F+   +K C  L R A  + S  V I+     S
Sbjct:   88 DDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYSQSQLANLT-----VCHPAWSAPRRRAMDLCT----------------FVFSYLLPVLVLSLTYARTLHYLWRTVDPVAAGSGS-------------------QRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWF----GRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRRAPRRASGRVCILAPGNHS 330          
BLAST of Galanin receptor type 2 vs. Ensembl Mouse
Match: Sstr4 (somatostatin receptor 4 [Source:MGI Symbol;Acc:MGI:105372])

HSP 1 Score: 68.1662 bits (165), Expect = 8.047e-12
Identity = 72/314 (22.93%), Postives = 145/314 (46.18%), Query Frame = 1
Query:  268 WVIIFIVGTLSNGCVIFILTR-VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXX-XXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRN-EVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLP---TQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFK 1191
            + ++ +VG + N  VIF++ R  + K+  +I  + LA+ D L ++ V  + +   ++  ++ F  VLC  V  +  + +F+S   L  L+V R++AVVHP +              +   +     ++P+A++    D    +G                  C   +P+     ++ I  FLL +LLP ++I L   LIV K+R   +   +++                     +R+   ++T++V++V T++ +CW+P    QL+N++  +             V  +S  LS+A++C NPI+Y  +++ F+
Sbjct:   51 YALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASA--AALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVF---ADTRPARG-------------GEAVACNLHWPHPAWSAVFVIYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQ---------------------RRRSEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFVTSLDAT---------VNHVSLILSYANSCANPILYGFLSDNFR 316          
BLAST of Galanin receptor type 2 vs. Ensembl Mouse
Match: Npy4r (neuropeptide Y receptor Y4 [Source:MGI Symbol;Acc:MGI:105374])

HSP 1 Score: 67.0106 bits (162), Expect = 1.850e-11
Identity = 86/390 (22.05%), Postives = 161/390 (41.28%), Query Frame = 1
Query:  196 IDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHP--WQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDL---------FPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNV---WYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKK---QCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKT 1314
            +D  Y+     Q    ++ +++  + I  I+G L N C+IF+ TR + KS    + +        ++ ++    T+ Y+  DY+ F +VLC ++ FI  +++  S   L+ + + R   +++P  W+  +  A                    V I+F V     +    N TL  D    N  K  + L         + + ++R IY   + L  Y +P   I++    I ++L+ +               +   H CS+R  + +    R+  M++ + T + V WLP  + N    WY         N     +  +   L+ ASTC+NP +Y  +N  FK  +K     C C  R  +     + + +  + L KGS ++  K+
Sbjct:   24 LDSPYNFSDGCQDSAELLAFIITTYSIETILGVLGNLCLIFVTTRQKEKSNVTNLLIANLAFSDFLMCLICQPLTVTYTIMDYWIFGEVLCKMLTFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSIFQAYLGI----------------VVIWF-VSCFLSLPFLANSTLN-DLFHYNHSKVVEFLEDKVVCFVSWSSDHHRLIYTTFLLLFQYCIPLAFILVCYIRIYQRLQRQ-------------KHVFHAHACSSRAGQMK----RINSMLMTMVTAFAVLWLPLHVFNTLEDWYQEAIPACHGN----LIFLMCHLLAMASTCVNPFIYGFLNINFKKDIKALVLTCHC--RSPRGESEHLPLSTVHTDLSKGSMRMGSKS 372          
BLAST of Galanin receptor type 2 vs. Ensembl Mouse
Match: Tacr2 (tachykinin receptor 2 [Source:MGI Symbol;Acc:MGI:98477])

HSP 1 Score: 63.1586 bits (152), Expect = 3.731e-10
Identity = 62/275 (22.55%), Postives = 110/275 (40.00%), Query Frame = 1
Query:  427 YSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRT---IYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQT------LSFASTCINPIVYSVVNETFKIAVK---KQCP 1215
            Y+S + + F    C   +     A+F S   +  +   R++A+VHP+Q R+ +     +               +A+ + V            T+  D        KC   +PN N      +Y ++VF+L Y LP + ++   Y ++               T+ K + +  H      +R  Q + +  K ++LV   + +CWLP  L     Y     F ++  + Y KFI Q       L+ +ST  NPI+Y  +N  F+   +   + CP
Sbjct:   93 YASHNIWYFGSTFCYFQNLFPVTAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAV---------------IAVIWLVALALASPQCFYSTITVD----QGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLV-VMFAAYSVI-------------GLTLWK-RAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHL-----YFILGTFQED--IYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCP 326          
BLAST of Galanin receptor type 2 vs. Ensembl Mouse
Match: Npffr2 (neuropeptide FF receptor 2 [Source:MGI Symbol;Acc:MGI:1860130])

HSP 1 Score: 62.3882 bits (150), Expect = 8.122e-10
Identity = 66/272 (24.26%), Postives = 117/272 (43.01%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTL---NKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPT-QLVNVWYYTDPKRFPKNRRMQ--YVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPS 1248
            F   +C I   +  +++ +S   L+ + V RF  VV+P++ ++           I  +     + P AI   V++    +  L   NKT    W        C++ +P    R IY  ++F   YL P   I++M   I   L          +   GK + +  H+      +K+Q   +V KM++ V+ L+ + WLP   L+ +  YTD    P   R+   Y+   +  L+F ++ +NPI+Y   NE F+   +       + AKP  +
Sbjct:  113 FGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVTIVIIWGLAIAIMT-PSAIMLHVQEEKYYRVRLSSHNKTSTVYW--------CREDWPRHEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTA------AHCTGKQRPVQWHVS-----KKKQ---KVIKMLLTVALLFILSWLPLWTLMMLSDYTDLS--PNKLRIINIYIYPFAHWLAFCNSSVNPIIYGFFNENFRNGFQDAFQICQKKAKPQEA 359          
BLAST of Galanin receptor type 2 vs. UniProt/SwissProt
Match: sp|F1R332|GAL2A_DANRE (Galanin receptor 2a OS=Danio rerio OX=7955 GN=galr2a PE=2 SV=2)

HSP 1 Score: 90.8929 bits (224), Expect = 2.117e-18
Identity = 83/357 (23.25%), Postives = 163/357 (45.66%), Query Frame = 1
Query:  274 IIFIVGTLSNGCVIFILTR---VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFP--NQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLV--NVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR--------VAKPSPSVIIIKSNKSSLLKGSQQ 1299
            +IF+VGT+ N  V+ +L R   +  KS    I          I+  V    T++  + D + F   +C  VHFI+Y+ +++S   L  +++ R+LA+ +P ++R       +       +        ++++F    ++             + QQ  +       P  + ++R    I  F+  YL+P + + +     +R L   V+   + S++                   R+ + +VTKM+I+V+ L+C+CWLP  LV   +W+      FP N     ++ +S  +++A++C+NPIVY++V++ F+   KK   C FR          +P+ +V ++++  S   +GS  
Sbjct:   27 MIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIY--TMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSR-------ETRTPRNALTSISLVWALSLFFSSPYLS-------------YYQQMDLDGTTVCIPAWSVHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSES-------------------RKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWF----GHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGCAFRNRVVNRIHTVQPAQTVSLMEAASS---EGSNH 335          
BLAST of Galanin receptor type 2 vs. UniProt/SwissProt
Match: sp|O08726|GALR2_RAT (Galanin receptor type 2 OS=Rattus norvegicus OX=10116 GN=Galr2 PE=2 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 1.094e-17
Identity = 65/284 (22.89%), Postives = 132/284 (46.48%), Query Frame = 1
Query:  439 DYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQ--LVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVA--KPSPSVIIIKSNKSS 1278
            D + F  +LC  VHF++++ + +S+  L  +++ R+LA+ +P  +R       ++      +        +A+ F    ++  + +          Q  ++  C   +     R +  +  F+ +YLLP + + L     +R L   V+     S +                   ++ + +VT+M+I+V+ L+C+CW+P    ++ VW+     RFP  R    ++ +S  +S+A++C+NPIVY++V++ F+   +K C  L R A  + S  V I+     S
Sbjct:   89 DDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSR-------ELRTPRNALAAIGLIWGLALLFSGPYLSYYRQS----------QLANLTVCHPAWSAPRRRAMD-LCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGS-------------------QRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWF----GRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHS 331          
BLAST of Galanin receptor type 2 vs. UniProt/SwissProt
Match: sp|O88854|GALR2_MOUSE (Galanin receptor type 2 OS=Mus musculus OX=10090 GN=Galr2 PE=2 SV=2)

HSP 1 Score: 87.4261 bits (215), Expect = 3.056e-17
Identity = 67/287 (23.34%), Postives = 133/287 (46.34%), Query Frame = 1
Query:  439 DYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDW--PQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQ--LVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVA--KPSPSVIIIKSNKSS 1278
            D + F  +LC  VHF++++ + +S+  L  +++ R+LA+ +P  +R + + + A  A  + W +    S P   Y+    +  +           W  P++ ++  C                 F+ +YLLP + + L     +  L   V+     S +                   ++ + +VT+M+++V+ L+C+CW+P    ++ VW+     RFP  R    ++ +S  +S+A++C+NPIVY++V++ F+   +K C  L R A  + S  V I+     S
Sbjct:   88 DDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYSQSQLANLT-----VCHPAWSAPRRRAMDLCT----------------FVFSYLLPVLVLSLTYARTLHYLWRTVDPVAAGSGS-------------------QRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWF----GRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRRAPRRASGRVCILAPGNHS 330          
BLAST of Galanin receptor type 2 vs. UniProt/SwissProt
Match: sp|O43603|GALR2_HUMAN (Galanin receptor type 2 OS=Homo sapiens OX=9606 GN=GALR2 PE=1 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 2.892e-16
Identity = 60/282 (21.28%), Postives = 124/282 (43.97%), Query Frame = 1
Query:  439 DYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQ--LVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSS 1278
            D + F  +LC  VHF++++ + +S+  L  +++ R+LA+ +P  +R                        + + +G+  +    G           Q  ++  C   +     R +  I  F+ +YLLP + + L     +R L   V+     S                     R+ + +VT+M+++V+ L+C+CW+P    ++ VW+     +FP  R    ++ +S  +S+A++C+NPIVY++V++ F+   +  C  L   A    S  +  + + +
Sbjct:   89 DGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSR-------------ELRTPRNALAAIGLIWGLSLL--FSGPYLSYYRQS--QLANLTVCHPAWSAPRRRAMD-ICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGA-------------------RRAKRKVTRMILIVAALFCLCWMPHHALILCVWF----GQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGT 329          
BLAST of Galanin receptor type 2 vs. UniProt/SwissProt
Match: sp|E7F7V7|GAL2B_DANRE (Galanin receptor 2b OS=Danio rerio OX=7955 GN=galr2b PE=2 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 2.753e-15
Identity = 79/334 (23.65%), Postives = 151/334 (45.21%), Query Frame = 1
Query:  274 IIFIVGTLSNGCVIFILTR------------VENKSVYD----IICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCL 1221
            +IF++GT+ N  V+ +L R            + N SV D    I CV    T               YS + +  F   +C +VHF + + +++S+  L  ++V R+LA+ +P ++R + +   A +A  + W +    + P   Y+ + D        +      W               ++NR +     F+  Y++P + + L     ++ L   V+     S++                   ++ + +VTKM+I+V+ L+C+CWLP  +V + Y Y D   FP N+     + +S  +++A++C+NPIVY++V++ F+   KK   C+
Sbjct:   35 LIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATI--------------YSLEGWV-FGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSYYDLIDFEN-----SNVCVPGW--------------EEHNRKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSES-------------------KRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYGD---FPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCI 312          
BLAST of Galanin receptor type 2 vs. TrEMBL
Match: A0A193KUD3 (GCR116 OS=Schmidtea mediterranea OX=79327 GN=gcr116 PE=2 SV=1)

HSP 1 Score: 869.766 bits (2246), Expect = 0.000e+0
Identity = 540/541 (99.82%), Postives = 540/541 (99.82%), Query Frame = 1
Query:   49 MNKEFPEFLKLYYRFINTKTKWREIQEIYPIIKSMIKNSWFNTTDLIRIIDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTNVIENRNVFISHFTEDPASLRGXXXXXXXXXXXXXXXLLGLAXXXXXXXXXXXPFVESQASCSVFSFEGFTDNLDSTNDIVSYNLITKV 1671
            MN EFPEFLKLYYRFINTKTKWREIQEIYPIIKSMIKNSWFNTTDLIRIIDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICVGLALTDLLILIVVIPITTMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMISAKEAKIACCIAWIIGGCCSIPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKTKLKKSLSDNSLVKNNNNNDENLKNCKKLKTNVIENRNVFISHFTEDPASLRGNNNNNKNNSNNYKKSLLGLASDNKKNKKSNSPFVESQASCSVFSFEGFTDNLDSTNDIVSYNLITKV
Sbjct:    1 MNMEFPEFLKLYYRFINTKTKWREIQEIYPIIKSMIKNSWFNTTDLIRIIDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICVGLALTDLLILIVVIPITTMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMISAKEAKIACCIAWIIGGCCSIPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKTKLKKSLSDNSLVKNNNNNDENLKNCKKLKTNVIENRNVFISHFTEDPASLRGNNNNNKNNSNNYKKSLLGLASDNKKNKKSNSPFVESQASCSVFSFEGFTDNLDSTNDIVSYNLITKV 541          
BLAST of Galanin receptor type 2 vs. TrEMBL
Match: A0A193KUA9 (GCR080 OS=Schmidtea mediterranea OX=79327 GN=gcr080 PE=2 SV=1)

HSP 1 Score: 166.007 bits (419), Expect = 8.879e-42
Identity = 125/393 (31.81%), Postives = 216/393 (54.96%), Query Frame = 1
Query:  139 IIKSMIKNSWFNTTDLIR-IIDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQ-QNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPH-------------ICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCP-----CLFRVAKPSPSVII 1257
            ++K +  +S  N ++ ++ ++  +Y+  +      N V YL+  W++I + G +SN  VI  L R   K +Y+I C+GLA TD+  L++ +P+T++ Y   ++      +C ++++++   +FSS+ +L+ LT +RF+AV+HPW+NR ++   AK AC I W IG   S P   YF   D  K    +         Q  N+  KC+  FP+  +R I  I +   +YL+PF+ I++MN ++V  ++ E  ++      + K      H             + +++  R+RQ++ RVT +V+LV+++Y +CWLP  ++N WY   P  FP    M+YV+++SQTLSF S C+NPIVYS+ ++ FK A   + P      L R   P   +I+
Sbjct:   32 LMKHLNDDSIRNESEKLKALLHSKYESKVGAFKLSNQVYYLVAIWILICVTGVVSNLVVIITLWRNPCKLIYEIFCIGLAFTDIGFLLLAVPLTSVHYLLLNWI-LGSFMCKLINYLIQSVVFSSSLILVGLTFSRFIAVLHPWKNRRMTLNGAKWACIIGWFIGFSISTP---YFYYHDTEKSDSWMRFITRNRTNQFVNNPYKCRLEFPSNESRYIVIIGLLNTSYLIPFIGILIMNAMVVCYVQKECLKEKGTKKEIKKEVKFPEHYRDSLISNDIVNKVKASKLFRRRQMQKRVTNLVLLVTSVYGLCWLPINIINAWYNLSPASFPSTPAMEYVRYVSQTLSFCSACVNPIVYSIASKAFKSAFIDRFPFLKNFTLHRKHSPKTEIIL 420          
BLAST of Galanin receptor type 2 vs. TrEMBL
Match: A0A504Y8V1 (Protein trapped in endoderm-1 OS=Fasciola gigantica OX=46835 GN=FGIG_04549 PE=4 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 6.031e-36
Identity = 130/396 (32.83%), Postives = 190/396 (47.98%), Query Frame = 1
Query:  271 VIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVK--------------GTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLR------------------------------------NEVNQDYEKSDTVGK--------------------------------PKLLSPHICSTREI-RKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQ 1209
            + I I+G L N  VI +LT    + VY+  CVGLA+TDL  L    PIT + Y  + +  F    C + +F+V V +FSSA MLL LT +RFL+VV PWQN  ++  +AK+ C  AWI G   + PV ++  +    +V               G  N   +T   Q +S+  C+ LFP+Q++R  Y +LV L TY++PF+ I++MN  I+ KL+                                    N  N +  KS   GK                                P + +  I   ++  +KR+ R + TK+VILV+TL+CVCWLPT ++N W   D   FP    M   K ISQ LSFA++C+NPIVY ++  TF+  +  +
Sbjct:   74 IAIAIIGVLGNMLVICVLTGSHTRLVYETFCVGLAVTDLTYLTFTTPITVVQYFFRGWI-FGLFWCKVFNFVVQVTVFSSAFMLLGLTTSRFLSVVLPWQNLKMTELQAKLFCLGAWIAGVIFASPVLVFQVLMPSREVSLNLNIVRCNGSSPMGIENPMNDTHTCQTHSVVLCRGLFPSQSSRMGYQLLVLLSTYVIPFVGILIMNSTIIYKLQKRNVIERHSRRRQQRPDSTFFVRNNLFRRRCSSKSCNSPNPEINKSAEAGKSNAVPETEIPLEQLSTAEDESRIDQTNLVRKTPSMTAMEIVQIQKAEKKRRTRTKATKLVILVTTLWCVCWLPTHIINSWLNFDEASFPFTPEMVASKLISQMLSFAASCVNPIVYGIMTGTFRAKISTK 468          
BLAST of Galanin receptor type 2 vs. TrEMBL
Match: A0A183A994 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS3529 PE=4 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 1.614e-29
Identity = 128/415 (30.84%), Postives = 197/415 (47.47%), Query Frame = 1
Query:  271 VIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQ---FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIY---FGVEDITKVKGTL-----------------NKTLE--TDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLL--------------------------------PFMSIILMNYLIVRKLRNEVNQD---------------------------YEKSDTVGKPK----------LLSPH--ICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            + I IVG L N  VI +L     + VY+  CVGLA+TDL  L    PIT + Y    YF+   F    C + +F+V V +FSSA MLL LT +RFL+VV PWQN  ++  +AK+ C  AWI G   + PV ++       ++T+ + +                  N+T+E  T    Q S+  C+ LFP+Q++R  Y +LV L TY++                                P  S+ + N ++ R+ R   +++                           ++ ++ V  P           LL+P   +   +  +KR+ R + TK+V+LV+TL+CVCWLPT ++N W   D   FP    M   K +SQTLSFA++C+NP+VY ++  TFK  +  +   +FR
Sbjct:   77 IAIAIVGVLGNLLVICVLIGSHTRLVYETFCVGLAVTDLTYLTFTTPITIVQY----YFRGWIFGLFWCKVFNFVVQVTVFSSAFMLLGLTTSRFLSVVLPWQNLKMTELQAKLFCLGAWIAGVIFASPVLVFQVLMPSREVTRYRHSAPGKNMTTTCLDVTEAVSNETMEFRTMTTVQESVVLCRGLFPSQSSRMGYQLLVLLSTYVIPFVAILIMNSTIIYKLQQRNVMERHERARKRQPDSSLSIRNNILFRRKRASKSKENSQLSSGDPGQAVTSRASSEHQLELEPFQPTEAVSGPNRDSFVTKNTTLLNPMELVKMQKAEKKRRTRTKATKLVVLVTTLWCVCWLPTHIINSWLNFDEASFPFTPEMVASKLVSQTLSFAASCVNPVVYGIMTGTFKATISNK---MFR 484          
BLAST of Galanin receptor type 2 vs. TrEMBL
Match: A0A448XC80 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS26873 PE=4 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 1.749e-24
Identity = 53/109 (48.62%), Postives = 73/109 (66.97%), Query Frame = 1
Query:  901 SDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            S  VG P + S      +  +KR++R RVTK VI+V++LY  CWLPTQ +N W+  D   FP N  M+  KFISQTLSFA++CINPIVYS+++ +F++A+  Q   L R
Sbjct:  121 SSQVGAPFVGSQLRADAKLEKKRKLRARVTKQVIVVTSLYGFCWLPTQFINAWFNIDRHGFPMNHAMKQAKFISQTLSFAASCINPIVYSLMSSSFRMAMAHQFHGLIR 229          
BLAST of Galanin receptor type 2 vs. Ensembl Cavefish
Match: galr2a (galanin receptor type 2 [Source:NCBI gene;Acc:103028491])

HSP 1 Score: 86.6557 bits (213), Expect = 5.431e-18
Identity = 84/328 (25.61%), Postives = 153/328 (46.65%), Query Frame = 1
Query:  277 IFIVGTLSNGCVIFILTRVENKS--VYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLV--NVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSP 1245
            IF+ GT+ N  V+ ++ R    S  +  +  V L   DL  +++ +P+    Y+  ++ +F  + C   HF VY+ + +SA  L  +++ R+LA+ +P + R M + + A I   + W +    S P   Y+   D+    GT       D+ Q+ ++  C                 F+  YL+P + + L     +R L   V+   + S+                    R+ + RVTKM+I+V+ L+C+CWLP  LV   +W+      FP N     ++ +S  +++ ++C+NPIVY++V++ F+   +K      RV K  P
Sbjct:   27 IFVAGTVGNSLVLAVVLRGGRASAKITSVFIVNLCAADLGFIVLCVPVQAAVYTLPEW-RFGSLACRTAHFAVYLTMHASALTLTAVSLDRYLAIRYPLRAREMRTPRNALICIGVVWAVSLVLSSPYLSYYQQMDL---DGTTVCIPAWDYQQRRAMDVCT----------------FVFGYLIPVLVLSLTYARTIRYLWTSVDPVQDASEC-------------------RRAKRRVTKMIIIVAVLFCLCWLPHHLVILCMWF----GHFPLNHTTYVLRILSHLVAYTNSCLNPIVYALVSKHFRKGFRK---VFGRVGKKRP 308          
BLAST of Galanin receptor type 2 vs. Ensembl Cavefish
Match: galr2b (galanin receptor type 2-like [Source:NCBI gene;Acc:103040671])

HSP 1 Score: 80.4925 bits (197), Expect = 5.682e-16
Identity = 66/293 (22.53%), Postives = 137/293 (46.76%), Query Frame = 1
Query:  433 SQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLF-RVAKPSPSVIIIKSNKSSLLKGSQQL 1302
            S + + F   +C +VHF + + +++S+  L  ++V R+LA+ +P ++R + +   A +A  I W +    + P   Y+ + D        +      W               ++NR +     F+  Y++P + + L     ++ L   V+     S++                   ++ + +VTKM+I+V+ L+C+CWLP  +V + Y Y D   FP N+     + +S  +++A++C+NPIVY++V++ F+   KK   C+  +  +    V+ + +       GS ++
Sbjct:   89 SLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVIIWGLSLIFAGPYLSYYDLIDFEN-----SNVCVPGW--------------EEHNRKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDVMSES-------------------KRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYGD---FPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILSKKGRNKVHVVHVANTVPGFEGGSTEV 340          
BLAST of Galanin receptor type 2 vs. Ensembl Cavefish
Match: npffr1l3 (neuropeptide FF receptor 1-like [Source:NCBI gene;Acc:111195007])

HSP 1 Score: 77.7962 bits (190), Expect = 8.230e-15
Identity = 87/354 (24.58%), Postives = 156/354 (44.07%), Query Frame = 1
Query:  223 FYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTR-----------VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKL-RNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQ----YVKFISQTLSFASTCINPIVYSVVNETFK---IAVKKQCPCLFR 1227
            +YQ    +    ++ ++ IF++  + NG V  I+ R           + N S+ D++     +   L+  ++             + FSDV+C +   +   ++ +S   L+ + V RF  +V+P++ ++           I  +       P A+   VE         N      +P    +  C + +P+   R +Y  ++F   YL+P + IILM   I  KL    V  + E++D  G P    P       + +R+++  V KM+I+V+ L+ + WLP  L  +   TD  R P+  +++    YV   S  L+FA++ +NPI+Y   NE FK    AV +Q  C  R
Sbjct:   50 YYQHSLGMAAVFILAYLFIFLLCMIGNGVVCLIVLRNRHMWTVTNAFILNLSISDLLVGIFCIPTTLVDNLITG-----------WPFSDVMCKLSGLVQGTSVCASVFTLVAIAVDRFRCIVYPFKPKLTLLVAKATIGLIWLLALVIMF-PSALMLTVEQERGHFTVYNGDYNLSYP----LYSCYETWPDPQMRKVYTTVLFAHIYLVPLVLIILMYGRIGAKLYTTTVLVNVEQAD--GTPHGKCP-------VSQRKIK--VIKMLIVVALLFMLSWLP--LWTLMLLTDYAR-PEGEQLELLTGYVFPFSHWLAFANSSVNPIIYGYFNENFKRGFHAVCQQTSCCSR 373          
BLAST of Galanin receptor type 2 vs. Ensembl Cavefish
Match: ENSAMXT00000053361.1 (G-protein coupled receptor 54 [Source:NCBI gene;Acc:103023540])

HSP 1 Score: 72.7886 bits (177), Expect = 1.792e-13
Identity = 65/262 (24.81%), Postives = 123/262 (46.95%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQN-RMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDW--PQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            F D +C  V F+  V + ++   L  ++  R    V+P ++ R  + + A I     WI     S P+ +Y  +ED               W  P+Q     C + FP++ +   + +  F+  YLLP ++I      +++++ +   +  + +  V        H+ S R I    +R++++KMV+++  L+ VCW P Q+  ++    P  F  N     +K  +  +S+A++ INPIVY  +  +F+ + +K  P LFR
Sbjct:  107 FGDFMCKFVAFLQQVTVQATCITLTAMSGDRCYVTVYPLKSLRHRTPRVAMIVSICIWIGSFILSTPIFLYQRLED-------------GYWYGPRQ----YCMERFPSKAHERAFILYQFIAVYLLPVLTISFCYSFMLKRVGHPTVEPVDSNHQV--------HLLSERTI---SIRSKISKMVVVIVLLFTVCWGPIQIFALFQSFYPN-FKVNYATYKIKTWANCMSYANSSINPIVYGFMGASFRKSFRKTFPFLFR 339          
BLAST of Galanin receptor type 2 vs. Ensembl Cavefish
Match: ENSAMXT00000033000.1 (G-protein coupled receptor 54 [Source:NCBI gene;Acc:103023540])

HSP 1 Score: 72.7886 bits (177), Expect = 2.001e-13
Identity = 65/262 (24.81%), Postives = 123/262 (46.95%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQN-RMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDW--PQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            F D +C  V F+  V + ++   L  ++  R    V+P ++ R  + + A I     WI     S P+ +Y  +ED               W  P+Q     C + FP++ +   + +  F+  YLLP ++I      +++++ +   +  + +  V        H+ S R I    +R++++KMV+++  L+ VCW P Q+  ++    P  F  N     +K  +  +S+A++ INPIVY  +  +F+ + +K  P LFR
Sbjct:  106 FGDFMCKFVAFLQQVTVQATCITLTAMSGDRCYVTVYPLKSLRHRTPRVAMIVSICIWIGSFILSTPIFLYQRLED-------------GYWYGPRQ----YCMERFPSKAHERAFILYQFIAVYLLPVLTISFCYSFMLKRVGHPTVEPVDSNHQV--------HLLSERTI---SIRSKISKMVVVIVLLFTVCWGPIQIFALFQSFYPN-FKVNYATYKIKTWANCMSYANSSINPIVYGFMGASFRKSFRKTFPFLFR 338          
BLAST of Galanin receptor type 2 vs. Ensembl Sea Lamprey
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 78.5666 bits (192), Expect = 3.592e-16
Identity = 53/257 (20.62%), Postives = 117/257 (45.53%), Query Frame = 1
Query:  439 DYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQ 1209
            D + F   LC  VHFI+++ +F+S+  L  ++V R+LA+ +P ++R       ++               +A+ F    ++  +    + +    P              +  R +  ++ F+  YL+P   + L     ++ L   V+   E S++                   ++ + +VT M+++V+ L+C CWLP  ++ ++++     FP        + +S  +S+A++C+NP+VY++V++ F+   +K 
Sbjct:   92 DGWIFGSFLCKAVHFIIFLTMFASSFTLAAVSVDRYLAIRYPLRSR-------ELRTPRKAAAVIAAIWGLALVFAGPYLSYYQAVTFQNMSMCMPVWA-----------KEPRKLMDMVTFVCGYLVPVSVLGLAYAFTLKYLWTAVDPLEEMSES-------------------KRAKRKVTTMILIVAGLFCACWLPHHVLILYFWFG--HFPLTHATYAFRLLSHCMSYANSCLNPLVYALVSKHFRKGFRKA 309          
BLAST of Galanin receptor type 2 vs. Ensembl Sea Lamprey
Match: kiss1rb (KISS1 receptor b [Source:ZFIN;Acc:ZDB-GENE-060526-54])

HSP 1 Score: 70.0922 bits (170), Expect = 2.905e-13
Identity = 80/339 (23.60%), Postives = 157/339 (46.31%), Query Frame = 1
Query:  262 IFWVIIFIVGTLSNGCVIFILTR-VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRV-AKPSPSVIIIKSNK 1272
            + + +I +VG + N  VIF++T+  + ++V +   V LA TD++ L+  +P T   Y    +  F D +C  V+++  V + ++   L  ++V R    V+P ++                       I + I+ G   ++      +KT   +W    +   C D FP+  +   + +  F+L Y+LP ++I +   ++++K+        E  D   + ++L+         R    R +VT+MV++V  ++ +CW P QL  ++    P  F  +     +K  +  +S+A++ INP VY  + ++F+   KK  PCLF+    P+P     + N 
Sbjct:   41 LLFALIMLVGLVGNSLVIFVITKNRQMRTVTNFFIVNLAGTDIIFLVCCVPFTATLYPLPSWV-FGDFMCKFVNYLQQVTVQATCMTLTAMSVDRCYVTVYPIRS------------LQHRTPCLAACISIGIWIGSLVMSLPMALYHKTDTKEWYGPKTY--CFDAFPSVPHEHAFVLYSFVLVYMLPLVTISVCYSIMIKKIGRPA---VEPQDDNVQLQMLTE--------RNEATRAKVTRMVVVVVLVFMLCWGPIQLFILFQSFYP-HFAISYTTYKLKTWANCMSYANSSINPFVYCFMGDSFRKTFKKAFPCLFKARVAPAPDAAYTEMNN 352          
BLAST of Galanin receptor type 2 vs. Ensembl Sea Lamprey
Match: oprk1 (opioid receptor, kappa 1 [Source:ZFIN;Acc:ZDB-GENE-030729-1])

HSP 1 Score: 63.929 bits (154), Expect = 1.844e-11
Identity = 68/274 (24.82%), Postives = 121/274 (44.16%), Query Frame = 1
Query:  427 YSSQDYFQ----FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNR--TIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQC-PCLFR 1227
            + S DY      F +V+C +V  I Y  +F+S   L  ++V R++AV HP +                  +   C   ++   G+  I  V GT  K        +  I +C   FP+   +   +  I VF+  ++LP + I++   L+V +LR                +LLS     ++E + R +R R+T+MV++V  ++ +CW P  L  +              +    +I   L + ++C+NP++Y+ ++E FK   K+ C P  FR
Sbjct:   30 FQSADYLMGSWPFGEVICKVVMSIDYYNMFTSIFTLTIMSVDRYIAVCHPVK-------ALDFRTPSKAKLINICIWILSSAIGIPVI--VMGTAKK--------EEGIIECILDFPHPAVKWENLLKICVFIFAFILPVLIIVVCYSLMVLRLRTV--------------RLLS----GSKE-KDRNLR-RITRMVLIVVAIFVICWTPIHLFVI--IKSRVSISDTPTVSAAWYICVALGYTNSCLNPVLYAFLDENFKRCFKEFCFPAAFR 264          
BLAST of Galanin receptor type 2 vs. Ensembl Sea Lamprey
Match: sstr1a (somatostatin receptor 1a [Source:ZFIN;Acc:ZDB-GENE-090429-1])

HSP 1 Score: 63.1586 bits (152), Expect = 4.880e-11
Identity = 63/259 (24.32%), Postives = 112/259 (43.24%), Query Frame = 1
Query:  430 SSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQN-RMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRN-EVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLP---TQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFK 1191
            ++  ++ F   LC +V  +  + +F+S   L  LT  R++AVVHP +  R      AK      W +     +P+ +Y   +      GT+                C  L+P       + +  F + +LLP  +I L   LIV K+R   +   +++                    RKR  R +VT MV +V  ++  CW+P    QLVNV+         + ++   V  ++  L +A++C NPI+Y  ++++F+
Sbjct:   73 TALHHWPFGSSLCRLVLSVDGINMFTSVFCLTVLTFDRYVAVVHPIKAARYRRPSVAKTINAAVWALSMVIILPIVVY--ADTRVNADGTV---------------VCNLLWPRPEWSAAFVVYTFTVGFLLPVAAICLCYALIVAKMRAVALRAGWQQ--------------------RKRSER-KVTLMVTMVVAVFVACWMPFYVVQLVNVF---------EGQQGATVNQLAVILGYANSCANPILYGFLSDSFR 284          
BLAST of Galanin receptor type 2 vs. Ensembl Sea Lamprey
Match: prlh2r (prolactin releasing hormone 2 receptor [Source:ZFIN;Acc:ZDB-GENE-120411-41])

HSP 1 Score: 58.9214 bits (141), Expect = 1.034e-9
Identity = 76/338 (22.49%), Postives = 148/338 (43.79%), Query Frame = 1
Query:  229 QSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVEN-KSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLF-PNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVT-KMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVA 1233
            Q  + +  ++++F+  + +VG L N  +++++ RV+   +V +++   LA +DLL+  + +P+T  +      + F   +C  V  +  V+++ S   L  + V R++  V+P + R+       +                AI+  V         L  T   ++P+Q  +  C++ +   +  R  Y     +LTY LP + I L  + I  KL+N V                 P   +  +    + R R T ++++LV T + VCWLP  + N     D +   K      V+ +    + +S C NP +Y+ +++ F+  +KK      RVA
Sbjct:   15 QLIRTLKPFVVLFYTAVVVVGVLGNFLLVYVICRVKKMHNVTNLLIGNLAFSDLLMCAMCVPLTLAYVFDARGWVFGSFMCYFVFLMQPVSVYVSVFTLTVIAVDRYIVTVYPLRRRITIPTCGYLL--------------AAIW--VTACALAAPALAHTYYCEFPEQR-MTICEEFWIGTERERLAYAYSTLVLTYGLPLLVISLSYFKISVKLKNRV----------------VPGTVTQNQAEMDRARRRKTFRLLVLVVTAFSVCWLPLHIFNFLRDVDIRLIDKY-YFNLVQLLCHWFAMSSACYNPFIYAWLHDRFRSELKKMFTVKRRVA 318          
BLAST of Galanin receptor type 2 vs. Ensembl Nematostella
Match: EDO44000 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXB4])

HSP 1 Score: 66.6254 bits (161), Expect = 4.824e-12
Identity = 77/310 (24.84%), Postives = 146/310 (47.10%), Query Frame = 1
Query:  256 LLIFWVIIFIVGTLSNGCV-IFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNV-WYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVN 1179
            L + ++I+F+VG++ N  V + ++ R  +++  +I    LAL+DLL +++ +P     + +   + F + +C + + I+ V L +S + LL +T  R+ A+ +P + R+       I               VAI+  V  IT +            P+Q     C +++P      +Y+I +F++ Y+LP   I  +  LI  K+R    +  EKS           H+ +    ++ +  +++T M+I +  LY +C LP  +V +   Y D  +F K R   YV   +     A++ +NPI Y  +N
Sbjct:   16 LRLIFIIVFLVGSVGNLVVCMAVIRRKRSRTSNNIFTFNLALSDLLTVLIYVPTQMAAFENDHNWPFGNFVCQLAYVIIPVCLSASIATLLAITTDRYRAIAYPMRPRLSGKHVRAIL--------------VAIW-TVSIITALPLMFVAREVRPAPRQ---VYCDEVWPEGPYSRVYWIAIFVIQYILPLGMICALAMLIALKVRRNSLKMIEKSS----------HVLAAAVRQRMKQTSKITNMLIALVILYAICMLPQHVVYLCMVYGDLLQF-KYR--VYVLRFANVFPMANSALNPIAYGTLN 294          
BLAST of Galanin receptor type 2 vs. Ensembl Nematostella
Match: EDO49570 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGN9])

HSP 1 Score: 63.929 bits (154), Expect = 2.578e-11
Identity = 57/256 (22.27%), Postives = 112/256 (43.75%), Query Frame = 1
Query:  442 YFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQ 1209
            ++ F  ++C +V ++  V++ SS   LL +T+ RF+++V P + R+  +K   I      I        +A     +   +    +   +E   P  N ++  K           + +L+F++ Y+ P +++ ++   I R L    +     + T               E   ++ R RV KM++ V+ L+ VCWLP  +     +  P+ FP   +  Y  F+S  L  +++ INP +YS  N  F+   ++ 
Sbjct:   60 HWVFGPIVCKLVVYLQSVSVASSVLTLLAVTIDRFISIVFPLRGRIALSKAKYIVAVTWIISLSI----MAPLIDAQKAKQFPDGMYYCIEEWQPPFNPLEAPKS----------FTVLLFVVMYVAPLLTMAVLYCAICRTLWKRTSPGARITRT---------------ETHLQRSRKRVLKMLLAVTLLFAVCWLPLWIFQFIMFFSPQTFPCFSKPFY--FVSLFLGHSNSAINPFLYSFFNANFREGFRRA 284          
BLAST of Galanin receptor type 2 vs. Ensembl Nematostella
Match: EDO43123 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZM3])

HSP 1 Score: 62.003 bits (149), Expect = 1.282e-10
Identity = 67/325 (20.62%), Postives = 139/325 (42.77%), Query Frame = 1
Query:  268 WVIIFIVGTLSNGCVIFILTR-----------VENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFP-NQNNRTI-----YFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFK 1191
            +V+IF++G L N   I+++ R           + N ++ D++    ++   ++ + +      W        F   LC +V F ++V+L +S   ++ ++V RF+AV  P +  ++   +                    + + +  +  +      T+ TD  +++    C   +P   +  T+     +F L F+  Y  P + + ++  +I RKL        +     G  +               + R +V K++++V  L+ VCW PT +++ +   D  RF         KF+S  +S A++ INPI+Y ++NE F+
Sbjct:    5 YVVIFLIGFLGNAIGIYVVCRQTGFRMVTNLLIANMAIADLLVCVFSMPASVVHLYIRNK---WLPGT----FGIFLCKMVSFSMFVSLAASVFTIVFISVERFIAVFFPLRCELLKRPKLLT----------------VMIWAISALVMLPSLFLFTVWTD--ERHGEHYCVVSWPWGDDGETLRVLGRFFTLTFVFMYCCPVLFLAILYTMIARKLWVRAIPGNDTQSNRGATQ---------------RCRKKVIKLLMVVVALFAVCWFPTHVMHYFLVYDSNRF--YHLSDETKFLSFFVSHANSSINPILYILLNEGFR 287          
BLAST of Galanin receptor type 2 vs. Ensembl Nematostella
Match: EDO43998 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXA6])

HSP 1 Score: 62.3882 bits (150), Expect = 1.434e-10
Identity = 55/249 (22.09%), Postives = 110/249 (44.18%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNN-RTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKR-QVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFK 1191
            F + +C + + I+ + L +S  +LL ++  R+ A+ HP + R+       I               +AI + +  IT +   L     TD P  +    C +L+P       +Y+I +F++ Y++P   I  ++ +   K+R    Q+   S    + +++      T  +R+R +   ++ KM+I +  LY +C LP  ++  W           +   YV  ++     A+  +NPI+Y  +N+ F 
Sbjct:   85 FGNFMCQVAYIIIPLCLSASIGILLAISTDRYRAIAHPLRPRLTLMNVKII---------------IAIIWFLSFITSIP--LLFVAGTDRPDPSGKLYCSELWPRGTRYEEMYWIAIFVVQYVIPLAVIAALSRVTAMKIR----QNSFFSSARKRSQIV------TTAVRQRLKQSTKIAKMLIGLVLLYSICMLPQHVIYFWLKYGNLNVLSYK--MYVFRLANVFPMANCALNPILYGTLNKEFA 304          
BLAST of Galanin receptor type 2 vs. Ensembl Nematostella
Match: EDO43930 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXA7])

HSP 1 Score: 61.6178 bits (148), Expect = 1.615e-10
Identity = 61/247 (24.70%), Postives = 114/247 (46.15%), Query Frame = 1
Query:  463 LCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLR-NEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNV-WY-YTDPKRF-PKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFK 1191
            +C +V+ ++ + + +S   LLT++  R+ A+V+P + ++   K   I               + + + V  +T +   L  T     P    +  C + + + +   +Y++ +F+L YL+P + I+    +I  KLR + +      S+T+ K          T   R +Q R ++TKM I +  LY +C LP  +V   WY + D   + PK R + Y   I      A++ +N I Y  +N+ FK
Sbjct:   64 MCHVVYLVLPICVSTSIGSLLTISCDRYRAIVYPMKPKLTMNKVKII---------------IGLIWFVSALTALPLALVVTTFRPAPH---VTYCTEFWRDASWGVLYWVAIFILQYLVPLIIIVSQAAVIAVKLRKSRIPMLSSSSETLYK---------KTLRTRIKQTR-KITKMYIALVLLYAICLLPQHVVATFWYNFGDFMEYSPKTRDLIYQ--IVNIFPMANSALNAIAYGTLNKEFK 280          
BLAST of Galanin receptor type 2 vs. Ensembl Medaka
Match: galr2a (galanin receptor type 2 [Source:NCBI gene;Acc:101155603])

HSP 1 Score: 82.8037 bits (203), Expect = 1.270e-16
Identity = 65/266 (24.44%), Postives = 129/266 (48.50%), Query Frame = 1
Query:  433 SQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNR-MXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLET-DWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWY-YTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCL 1221
            S + + F   +C +VHF + + +++S+  L  ++V R+LA+ +P ++R + +   A +A  + W +    + P   Y+ + D        N T+    W +Q+              R +     FL  Y++P + + L     ++ L   V+     S++                   ++ + +VTKM+I+V+ L+C+CWLP  +V + Y Y D   FP N+     + +S  +++A++C+NPIVY++V++ F+   KK   C+
Sbjct:   89 SLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSYYDLIDYA------NSTVCIPGWEEQD--------------RKVLDTCTFLFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSES-------------------KRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYGD---FPFNQTTYAFRLLSHCMAYANSCVNPIVYALVSKHFRKGFKKVFSCI 312          
BLAST of Galanin receptor type 2 vs. Ensembl Medaka
Match: si:dkey-1h24.2 (cholecystokinin receptor [Source:NCBI gene;Acc:101175467])

HSP 1 Score: 82.8037 bits (203), Expect = 1.738e-16
Identity = 76/299 (25.42%), Postives = 126/299 (42.14%), Query Frame = 1
Query:  445 FQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXX-XXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKL----RNEVNQDYE----KSDTVG-------------KPKLLS--PHICSTREI--------------RKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            F F   +C IV +++ V++  S   L+ + + R+ A+ +P Q+R    +        A  +I     +P   +  ++   K  GT+      DWP Q            Q  +T Y +L+F L + +P + +I    LI R+L    + E++Q+ E    K+  +G             KP      P + +T                  K Q + RV +M++++  LY VCW+P   VN W   D K   K      + FI   LS+ S C+NPI+Y  +N  F+ A+     C  R
Sbjct:   89 FIFGATMCKIVTYLMGVSVSISTFSLVAIAIERYSAICNPLQSRAWQTRSHAYRVIAATWVISLLIMVPYPFFSALKSFPKTNGTMGHMCRLDWPSQ------------QAEQTWYVLLLFTL-FFVPGVVMITAYGLISRELYRGIQFELSQNKETTGQKNGVMGSNDDDGCYIQVSKKPSFAVELPTLSATSSAIQAKTERARSNTSEAKLQAKRRVIRMLMVIVALYFVCWMPLYSVNTWKAFDDKSASKTLSGAPISFI-HLLSYTSACVNPIIYCFMNTRFRKALLSTFACCCR 373          
BLAST of Galanin receptor type 2 vs. Ensembl Medaka
Match: npffr1l2 (neuropeptide FF receptor 1 like 2 [Source:ZFIN;Acc:ZDB-GENE-060526-110])

HSP 1 Score: 71.633 bits (174), Expect = 7.175e-13
Identity = 66/255 (25.88%), Postives = 115/255 (45.10%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPT-QLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQC 1212
            FS+ +C +  F+  V++ +S   L+ + V RF  +V+P Q ++           I  +       P A+   VE +       N     D+ Q   +  C + F N   R IY  ++F   YLLP   I LM   I  KL + V  + E       P+L +      + + +++++  V KM+++V+ L+ V WLP   L+ +  Y    R   +    Y+   +  L+F+++ +NPIVY   N+ FK   +  C
Sbjct:  118 FSNTVCKMSGFVQGVSVSASVFTLVAIAVERFRCIVYPLQPKLTLLVAKVAIVSIWVLAVVILC-PAAVALTVEKVPFHYMVHNN----DFNQTLPLYTCYENFANPQMRKIYTAVLFAHIYLLPLAVITLMYISIGVKLCSSVVANRE-------PQLANIRRHGQQMVSQKKIK--VVKMLVVVTLLFMVSWLPLWTLMMMTDYGGLDRDQLDLLTSYIFPFAHWLAFSNSSVNPIVYGYYNKNFKRGFQSVC 358          
BLAST of Galanin receptor type 2 vs. Ensembl Medaka
Match: npffr1l2 (neuropeptide FF receptor 1 like 2 [Source:ZFIN;Acc:ZDB-GENE-060526-110])

HSP 1 Score: 71.2478 bits (173), Expect = 7.442e-13
Identity = 66/255 (25.88%), Postives = 115/255 (45.10%), Query Frame = 1
Query:  451 FSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPT-QLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQC 1212
            FS+ +C +  F+  V++ +S   L+ + V RF  +V+P Q ++           I  +       P A+   VE +       N     D+ Q   +  C + F N   R IY  ++F   YLLP   I LM   I  KL + V  + E       P+L +      + + +++++  V KM+++V+ L+ V WLP   L+ +  Y    R   +    Y+   +  L+F+++ +NPIVY   N+ FK   +  C
Sbjct:  100 FSNTVCKMSGFVQGVSVSASVFTLVAIAVERFRCIVYPLQPKLTLLVAKVAIVSIWVLAVVILC-PAAVALTVEKVPFHYMVHNN----DFNQTLPLYTCYENFANPQMRKIYTAVLFAHIYLLPLAVITLMYISIGVKLCSSVVANRE-------PQLANIRRHGQQMVSQKKIK--VVKMLVVVTLLFMVSWLPLWTLMMMTDYGGLDRDQLDLLTSYIFPFAHWLAFSNSSVNPIVYGYYNKNFKRGFQSVC 340          
BLAST of Galanin receptor type 2 vs. Ensembl Medaka
Match: ENSORLT00000022492.2 (cholecystokinin receptor-like [Source:NCBI gene;Acc:101161683])

HSP 1 Score: 71.2478 bits (173), Expect = 8.611e-13
Identity = 65/296 (21.96%), Postives = 125/296 (42.23%), Query Frame = 1
Query:  445 FQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHP-----WQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKL----RNEVNQDYEKSDT----------------------VGKPKLL--SPHICSTREIR-----------KRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAV 1200
            F F   +C IV +++ +++  S   L+ + + R+ A+ +P     WQ R      A       W++     +P  I   +  +   +G+ N T            KC+  +P Q     +++++ L+ + +P + +I+   LI R+L    R E+ Q  + +D                       V +P  +  S    S R+++           K + + RV +M++++  L+ +CW+P   VN W   D     +      + FI   LS+ S C+NPI+Y  +N  F+ A+
Sbjct:  125 FIFGAAMCKIVSYLMGISVSISTFSLVAIAIERYSAICNPLKSRVWQTR----SHAYRVIAATWVLAFIIMVPYPI---ISHLEPFQGSANTTAH----------KCRHKWPIQTAEQTWYVMLLLILFAIPGVVMIIAYGLISRELYRGIRFEMGQKKDSTDVKNGLTSTVSNVSDDGDGCYVTVVQRPHSMEMSTMAASIRQVKADRPRSNTSEAKLEAKKRVIRMLVVIVVLFFLCWMPLYCVNTWRAFDDSSATRALSGAPIAFI-HLLSYTSACVNPIIYCFMNTRFRKAL 402          
BLAST of Galanin receptor type 2 vs. Planmine SMEST
Match: SMESG000043375.1 (SMESG000043375.1)

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 417/417 (100.00%), Postives = 417/417 (100.00%), Query Frame = 1
Query:  421 MWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTNVIENRNVFISHFTEDPASLRGXXXXXXXXXXXXXXXLLGLAXXXXXXXXXXXPFVESQASCSVFSFEGFTDNLDSTNDIVSYNLITKV 1671
            MWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMISAKEAKIACCIAWIIGGCCSIPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKTKLKKSLSDNSLVKNNNNNDENLKNCKKLKTNVIENRNVFISHFTEDPASLRGNNNNNKNNSNNYKKSLLGLASDNKKNKKSNSPFVESQASCSVFSFEGFTDNLDSTNDIVSYNLITKV
Sbjct:    1 MWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMISAKEAKIACCIAWIIGGCCSIPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPSVIIIKSNKSSLLKGSQQLVPKTKLKKSLSDNSLVKNNNNNDENLKNCKKLKTNVIENRNVFISHFTEDPASLRGNNNNNKNNSNNYKKSLLGLASDNKKNKKSNSPFVESQASCSVFSFEGFTDNLDSTNDIVSYNLITKV 417          
BLAST of Galanin receptor type 2 vs. Planmine SMEST
Match: SMESG000036226.1 (SMESG000036226.1)

HSP 1 Score: 288.886 bits (738), Expect = 1.415e-91
Identity = 175/355 (49.30%), Postives = 248/355 (69.86%), Query Frame = 1
Query:  175 TTDLIRIIDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICST----REIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFR 1227
            T + + +I   Y   +  +SF N V+YL+  WV+I ++G +SN  VI +L++V  K VY+I C+GLA+TDL IL+  +PITT+ Y  + +  F D +C +V+F+VY+A+FSS  MLL LT+TRF+AVV PW+NR  S ++AK+AC I W++G   S PV IY+GV D    K +   + + +    NS+K C+  FPN+ ++TIYF+LVF+LTY+LPF  II+MN +IVR+L+ E  +  + +    + ++ S  +  T    RE  KRQ R+RVTK+VILV+ LYC+CWLPTQ+VN WYY DP  FP NRRMQY+KFISQTLSFAS CINPIVYS++++TFK   ++ CPC F+
Sbjct:   54 TVEFLDMISNLYKSRMGEESFYNEVKYLISVWVLICLIGVVSNIYVITVLSKVRQKIVYEIFCIGLAVTDLSILVFAVPITTLHYGMKIWI-FGDFICKMVNFLVYMAVFSSTMMLLILTITRFMAVVFPWENRSFSTQKAKMACYIIWLLGAIFSTPVLIYYGVGDENNTKDSNYSSGQNEQVDVNSLK-CQANFPNELSKTIYFVLVFVLTYILPFKCIIIMNTMIVRRLKREFGEKKQSNSLNSENRVSSSFMSKTKNSMRENEKRQRRSRVTKIVILVTMLYCICWLPTQIVNFWYYIDPSGFPTNRRMQYIKFISQTLSFASACINPIVYSIMSDTFKKTQERICPCCFQ 406          
BLAST of Galanin receptor type 2 vs. Planmine SMEST
Match: SMESG000003338.1 (SMESG000003338.1)

HSP 1 Score: 223.402 bits (568), Expect = 9.616e-67
Identity = 159/390 (40.77%), Postives = 240/390 (61.54%), Query Frame = 1
Query:   67 EFLKLYYRFINTKTKWREIQEIYPII-KSMIKNSWFNTTDLIRIIDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSP-HICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRV 1230
            EF K    F + K      + +Y II   ++K++   + +LI++I   Y+     + F +     +  W +I ++G + N  VI +  R +   VY+I C+GLALTDL  L++ +PIT + Y  + +  F + LC  V+FI Y +LFSSA MLL+LT +RFL+VV PW +R ++ K A  AC  AWI G  CS P+AIY+   ++  ++ +LN ++        SIK+C+D FP+  +R IYF  V    YL+PF+ II MN  I+  LR E N    K + V + K LS     S R  R++Q R++VTK+VI+++T YC+CWLPT L+NVWYYT PK FP+   MQY K ISQT+S+AS C+NP +YS+++++F+ +VKKQ P  +++
Sbjct:   12 EFFKNMNLFRSGKVNQTTFEYLYQIIIHYLVKDNSEYSLELIKMIQNEYN----KKKFVSQTSIWITLWSMICLIGIVGNSFVIAVFYRNKQHVVYEIFCIGLALTDLSFLLLTVPITILHYLLKSWV-FGNFLCRFVNFISYGSLFSSAIMLLSLTTSRFLSVVRPWDHRNMTLKGAITACAFAWIAGYLCSTPIAIYY---NVVPIQQSLNNSI--------SIKRCRDQFPSVISRQIYFSGVLAFAYLIPFIGIISMNCRIILALRKEGNL---KENIVEQKKPLSKTDFSSIRNKRQQQRRSKVTKLVIVITTSYCICWLPTHLLNVWYYTSPKTFPETIIMQYAKTISQTVSYASACLNPFIYSIISQSFQNSVKKQFPKFYQI 382          
BLAST of Galanin receptor type 2 vs. Planmine SMEST
Match: SMESG000003338.1 (SMESG000003338.1)

HSP 1 Score: 221.861 bits (564), Expect = 2.489e-66
Identity = 153/365 (41.92%), Postives = 231/365 (63.29%), Query Frame = 1
Query:  139 IIKSMIKNSWFNTTDLIRIIDKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSVYDIICXXXXXXXXXXXXXXXXXXXMWYSSQDYFQFSDVLCPIVHFIVYVALFSSASMLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSP-HICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRV 1230
            II  ++K++   + +LI++I   Y+     + F +     +  W +I ++G + N  VI +  R +   VY+I C+GLALTDL  L++ +PIT + Y  + +  F + LC  V+FI Y +LFSSA MLL+LT +RFL+VV PW +R ++ K A  AC  AWI G  CS P+AIY+   ++  ++ +LN ++        SIK+C+D FP+  +R IYF  V    YL+PF+ II MN  I+  LR E N    K + V + K LS     S R  R++Q R++VTK+VI+++T YC+CWLPT L+NVWYYT PK FP+   MQY K ISQT+S+AS C+NP +YS+++++F+ +VKKQ P  +++
Sbjct:   21 IIHYLVKDNSEYSLELIKMIQNEYN----KKKFVSQTSIWITLWSMICLIGIVGNSFVIAVFYRNKQHVVYEIFCIGLALTDLSFLLLTVPITILHYLLKSWV-FGNFLCRFVNFISYGSLFSSAIMLLSLTTSRFLSVVRPWDHRNMTLKGAITACAFAWIAGYLCSTPIAIYY---NVVPIQQSLNNSI--------SIKRCRDQFPSVISRQIYFSGVLAFAYLIPFIGIISMNCRIILALRKEGNL---KENIVEQKKPLSKTDFSSIRNKRQQQRRSKVTKLVIVITTSYCICWLPTHLLNVWYYTSPKTFPETIIMQYAKTISQTVSYASACLNPFIYSIISQSFQNSVKKQFPKFYQI 366          
BLAST of Galanin receptor type 2 vs. Planmine SMEST
Match: SMESG000003338.1 (SMESG000003338.1)

HSP 1 Score: 184.496 bits (467), Expect = 6.137e-54
Identity = 110/239 (46.03%), Postives = 159/239 (66.53%), Query Frame = 1
Query:  517 MLLTLTVTRFLAVVHPWQNRMXXXXXXXXXXXXXXXXXXXXXXPVAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFILVFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSP-HICSTREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRRMQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRV 1230
            MLL+LT +RFL+VV PW +R ++ K A  AC  AWI G  CS P+AIY+   ++  ++ +LN ++        SIK+C+D FP+  +R IYF  V    YL+PF+ II MN  I+  LR E N    K + V + K LS     S R  R++Q R++VTK+VI+++T YC+CWLPT L+NVWYYT PK FP+   MQY K ISQT+S+AS C+NP +YS+++++F+ +VKKQ P  +++
Sbjct:    1 MLLSLTTSRFLSVVRPWDHRNMTLKGAITACAFAWIAGYLCSTPIAIYY---NVVPIQQSLNNSI--------SIKRCRDQFPSVISRQIYFSGVLAFAYLIPFIGIISMNCRIILALRKEGNL---KENIVEQKKPLSKTDFSSIRNKRQQQRRSKVTKLVIVITTSYCICWLPTHLLNVWYYTSPKTFPETIIMQYAKTISQTVSYASACLNPFIYSIISQSFQNSVKKQFPKFYQI 225          
The following BLAST results are available for this feature:
BLAST of Galanin receptor type 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GALR26.023e-1721.28galanin receptor 2 [Source:HGNC Symbol;Acc:HGNC:41... [more]
NPFFR22.971e-1124.41neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc... [more]
NPFFR22.987e-1124.41neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc... [more]
NPFFR23.462e-1124.41neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc... [more]
SSTR53.281e-1026.92somatostatin receptor 5 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of Galanin receptor type 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npr-65.887e-1023.46NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
trhr-11.020e-923.66Thyrotropin-Releasing Hormone Receptor [Source:Un... [more]
npr-94.145e-826.76Galanin-like G-protein coupled receptor npr-9 [So... [more]
npr-128.551e-623.61NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
npr-128.737e-623.61NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
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BLAST of Galanin receptor type 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TkR99D2.906e-1222.96gene:FBgn0004622 transcript:FBtr0301656[more]
TkR99D3.023e-1222.96gene:FBgn0004622 transcript:FBtr0085507[more]
TkR99D4.271e-1222.96gene:FBgn0004622 transcript:FBtr0330298[more]
AstC-R17.202e-1124.43gene:FBgn0036790 transcript:FBtr0089578[more]
sNPF-R2.924e-1026.88gene:FBgn0036934 transcript:FBtr0332667[more]
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BLAST of Galanin receptor type 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
galr2a2.804e-1923.25galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
galr2a2.804e-1923.25galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
galr2a2.877e-1923.25galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
galr2b3.647e-1623.65galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-1311... [more]
galr2b3.647e-1623.65galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-1311... [more]
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BLAST of Galanin receptor type 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sp32.390e-1824.54Sp3 transcription factor [Source:Xenbase;Acc:XB-GE... [more]
sp32.919e-1824.54Sp3 transcription factor [Source:Xenbase;Acc:XB-GE... [more]
ENSXETT00000041298.11.680e-1724.62galanin receptor 3 [Source:NCBI gene;Acc:100488248... [more]
GALR23.288e-1725.69galanin receptor 2 [Source:NCBI gene;Acc:100486593... [more]
kiss1r2.291e-1325.72KISS1 receptor [Source:NCBI gene;Acc:100316929][more]
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BLAST of Galanin receptor type 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Galr24.368e-1823.34galanin receptor 2 [Source:MGI Symbol;Acc:MGI:1337... [more]
Sstr48.047e-1222.93somatostatin receptor 4 [Source:MGI Symbol;Acc:MGI... [more]
Npy4r1.850e-1122.05neuropeptide Y receptor Y4 [Source:MGI Symbol;Acc:... [more]
Tacr23.731e-1022.55tachykinin receptor 2 [Source:MGI Symbol;Acc:MGI:9... [more]
Npffr28.122e-1024.26neuropeptide FF receptor 2 [Source:MGI Symbol;Acc:... [more]
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BLAST of Galanin receptor type 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|F1R332|GAL2A_DANRE2.117e-1823.25Galanin receptor 2a OS=Danio rerio OX=7955 GN=galr... [more]
sp|O08726|GALR2_RAT1.094e-1722.89Galanin receptor type 2 OS=Rattus norvegicus OX=10... [more]
sp|O88854|GALR2_MOUSE3.056e-1723.34Galanin receptor type 2 OS=Mus musculus OX=10090 G... [more]
sp|O43603|GALR2_HUMAN2.892e-1621.28Galanin receptor type 2 OS=Homo sapiens OX=9606 GN... [more]
sp|E7F7V7|GAL2B_DANRE2.753e-1523.65Galanin receptor 2b OS=Danio rerio OX=7955 GN=galr... [more]
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BLAST of Galanin receptor type 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A193KUD30.000e+099.82GCR116 OS=Schmidtea mediterranea OX=79327 GN=gcr11... [more]
A0A193KUA98.879e-4231.81GCR080 OS=Schmidtea mediterranea OX=79327 GN=gcr08... [more]
A0A504Y8V16.031e-3632.83Protein trapped in endoderm-1 OS=Fasciola gigantic... [more]
A0A183A9941.614e-2930.84G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A448XC801.749e-2448.62G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
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BLAST of Galanin receptor type 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
galr2a5.431e-1825.61galanin receptor type 2 [Source:NCBI gene;Acc:1030... [more]
galr2b5.682e-1622.53galanin receptor type 2-like [Source:NCBI gene;Acc... [more]
npffr1l38.230e-1524.58neuropeptide FF receptor 1-like [Source:NCBI gene;... [more]
ENSAMXT00000053361.11.792e-1324.81G-protein coupled receptor 54 [Source:NCBI gene;Ac... [more]
ENSAMXT00000033000.12.001e-1324.81G-protein coupled receptor 54 [Source:NCBI gene;Ac... [more]
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BLAST of Galanin receptor type 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
galr2a3.592e-1620.62galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
kiss1rb2.905e-1323.60KISS1 receptor b [Source:ZFIN;Acc:ZDB-GENE-060526-... [more]
oprk11.844e-1124.82opioid receptor, kappa 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
sstr1a4.880e-1124.32somatostatin receptor 1a [Source:ZFIN;Acc:ZDB-GENE... [more]
prlh2r1.034e-922.49prolactin releasing hormone 2 receptor [Source:ZFI... [more]
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BLAST of Galanin receptor type 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Galanin receptor type 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO440004.824e-1224.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495702.578e-1122.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431231.282e-1020.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO439981.434e-1022.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO439301.615e-1024.70Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Galanin receptor type 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
galr2a1.270e-1624.44galanin receptor type 2 [Source:NCBI gene;Acc:1011... [more]
si:dkey-1h24.21.738e-1625.42cholecystokinin receptor [Source:NCBI gene;Acc:101... [more]
npffr1l27.175e-1325.88neuropeptide FF receptor 1 like 2 [Source:ZFIN;Acc... [more]
npffr1l27.442e-1325.88neuropeptide FF receptor 1 like 2 [Source:ZFIN;Acc... [more]
ENSORLT00000022492.28.611e-1321.96cholecystokinin receptor-like [Source:NCBI gene;Ac... [more]
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BLAST of Galanin receptor type 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000043375.10.000e+0100.00SMESG000043375.1[more]
SMESG000036226.11.415e-9149.30SMESG000036226.1[more]
SMESG000003338.19.616e-6740.77SMESG000003338.1[more]
SMESG000003338.12.489e-6641.92SMESG000003338.1[more]
SMESG000003338.16.137e-5446.03SMESG000003338.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30031058 ID=SMED30031058|Name=Galanin receptor type 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1722bp
AACAATTAATTGTTTAGATAGAACTTGCAACGATATCTACGCTTTGAAAT
GAATAAGGAGTTTCCAGAATTTCTGAAATTATATTACAGGTTTATTAACA
CAAAAACAAAATGGCGAGAAATTCAAGAGATTTACCCTATCATCAAGTCC
ATGATCAAGAACAGCTGGTTCAACACGACCGATTTGATACGAATCATTGA
TAAAAGATATGACATACTGTTGTTTTATCAAAGTTTCCAAAATATTGTTC
AGTATTTGCTGATCTTTTGGGTCATCATTTTCATCGTCGGCACTCTCAGC
AATGGCTGTGTAATTTTCATATTGACAAGAGTAGAAAACAAATCTGTCTA
TGACATCATTTGTGTAGGTCTTGCCCTAACCGACCTGTTGATTCTGATTG
TCGTGATACCGATAACTACAATGTGGTATTCCTCACAAGATTATTTCCAA
TTCAGTGATGTACTTTGCCCGATCGTCCATTTTATTGTTTATGTAGCGTT
ATTTTCTTCAGCATCAATGCTACTCACTTTGACCGTAACCAGATTTCTGG
CGGTCGTTCATCCTTGGCAAAACCGAATGATATCAGCAAAAGAAGCCAAA
ATAGCCTGCTGTATAGCGTGGATTATAGGAGGATGTTGTTCCATTCCAGT
TGCTATCTACTTCGGCGTTGAAGATATAACGAAAGTAAAAGGTACTTTGA
ATAAAACACTTGAGACAGATTGGCCACAGCAAAACAGCATTAAGAAATGC
AAGGATTTATTTCCCAATCAGAACAACCGAACTATTTATTTTATTTTGGT
ATTTCTGTTGACTTACCTTTTACCATTTATGAGCATAATTCTGATGAACT
ATTTGATCGTGAGGAAATTGAGAAACGAAGTTAATCAAGATTACGAGAAA
TCCGACACGGTTGGGAAACCTAAATTATTATCTCCACATATTTGCTCTAC
GAGAGAAATCCGTAAAAGGCAGGTAAGAAACCGAGTGACAAAAATGGTGA
TTCTGGTGTCGACTCTTTATTGCGTCTGTTGGTTGCCCACTCAACTAGTC
AACGTTTGGTATTATACGGATCCCAAGAGATTTCCGAAAAATCGCAGAAT
GCAATATGTAAAATTCATCAGCCAAACATTATCCTTCGCCAGCACTTGCA
TCAATCCAATTGTCTATTCAGTTGTTAATGAAACGTTTAAAATTGCCGTT
AAGAAACAATGCCCCTGTTTGTTTCGGGTGGCAAAACCGAGTCCTTCAGT
GATAATAATCAAATCAAACAAATCATCCTTATTGAAAGGTTCTCAGCAGC
TTGTACCCAAAACGAAACTGAAAAAATCCCTCAGTGACAATTCACTCGTC
AAAAATAATAATAATAATGACGAAAATCTAAAAAATTGCAAAAAACTCAA
AACCAATGTCATAGAAAATCGGAATGTGTTTATTTCACATTTCACTGAGG
ATCCGGCAAGTTTAAGGGGCAATAATAACAATAACAAAAACAATAGCAAT
AATTATAAAAAGAGCCTTTTGGGTCTTGCCTCGGATAATAAAAAGAATAA
AAAGTCAAATTCTCCATTTGTCGAATCTCAAGCCAGTTGCAGTGTCTTTT
CATTCGAAGGTTTTACGGACAATTTAGATTCGACAAATGATATTGTCAGT
TACAATTTAATTACTAAAGTTTAAATTGTTTTAATTTTTGATTTATTTAA
TATTTTTTATTGAAATGTGCAC
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protein sequence of SMED30031058-orf-1

>SMED30031058-orf-1 ID=SMED30031058-orf-1|Name=SMED30031058-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=542bp
MNKEFPEFLKLYYRFINTKTKWREIQEIYPIIKSMIKNSWFNTTDLIRII
DKRYDILLFYQSFQNIVQYLLIFWVIIFIVGTLSNGCVIFILTRVENKSV
YDIICVGLALTDLLILIVVIPITTMWYSSQDYFQFSDVLCPIVHFIVYVA
LFSSASMLLTLTVTRFLAVVHPWQNRMISAKEAKIACCIAWIIGGCCSIP
VAIYFGVEDITKVKGTLNKTLETDWPQQNSIKKCKDLFPNQNNRTIYFIL
VFLLTYLLPFMSIILMNYLIVRKLRNEVNQDYEKSDTVGKPKLLSPHICS
TREIRKRQVRNRVTKMVILVSTLYCVCWLPTQLVNVWYYTDPKRFPKNRR
MQYVKFISQTLSFASTCINPIVYSVVNETFKIAVKKQCPCLFRVAKPSPS
VIIIKSNKSSLLKGSQQLVPKTKLKKSLSDNSLVKNNNNNDENLKNCKKL
KTNVIENRNVFISHFTEDPASLRGNNNNNKNNSNNYKKSLLGLASDNKKN
KKSNSPFVESQASCSVFSFEGFTDNLDSTNDIVSYNLITKV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000418head
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 69..93
score: 21.05
coord: 147..169
score: 24.75
coord: 182..203
score: 21.22
coord: 355..381
score: 27.32
coord: 101..122
score: 28.54
coord: 248..271
score: 18.74
coord: 313..337
score: 25.79
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 85..373
e-value: 6.4E-37
score: 127.3
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 53..431
e-value: 5.9E-62
score: 211.2
NoneNo IPR availablePANTHERPTHR45695FAMILY NOT NAMEDcoord: 69..498
NoneNo IPR availableCDDcd150957tmA_KiSS1Rcoord: 72..381
e-value: 5.09708E-47
score: 163.607
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 41..402
NoneNo IPR availableTMHMMTMhelixcoord: 142..164
NoneNo IPR availableTMHMMTMhelixcoord: 354..376
NoneNo IPR availableTMHMMTMhelixcoord: 248..270
NoneNo IPR availableTMHMMTMhelixcoord: 317..339
NoneNo IPR availableTMHMMTMhelixcoord: 70..92
NoneNo IPR availableTMHMMTMhelixcoord: 185..207
NoneNo IPR availableTMHMMTMhelixcoord: 105..127
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 84..373
score: 35.216