Rho-associated protein kinase
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30031032 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Rho-associated protein kinase vs. Ensembl Human
Match: ROCK1 (Rho associated coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:10251]) HSP 1 Score: 393.66 bits (1010), Expect = 2.683e-116 Identity = 183/400 (45.75%), Postives = 264/400 (66.00%), Query Frame = 3 Query: 75 NVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 N++ D K ++ D L D L D L NK NF ++K K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL+FP D+++S A + + + DR VRLG+ +IK H+FF N +W W+T++D+ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y Sbjct: 16 NLLRDPKSEVNSDCLLDGLDALVYDL-DFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNK-EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRN-GVEEIKRHLFFKND--QWAWETLRDTVAPVVPDLSSDIDTSNFDDLEED----------KGEEETFPIPKAFVGNQLPFVGFTY 399
BLAST of Rho-associated protein kinase vs. Ensembl Human
Match: ROCK1 (Rho associated coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:10251]) HSP 1 Score: 390.578 bits (1002), Expect = 9.611e-114 Identity = 183/400 (45.75%), Postives = 264/400 (66.00%), Query Frame = 3 Query: 75 NVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 N++ D K ++ D L D L D L NK NF ++K K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL+FP D+++S A + + + DR VRLG+ +IK H+FF N +W W+T++D+ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y Sbjct: 16 NLLRDPKSEVNSDCLLDGLDALVYDL-DFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNK-EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRN-GVEEIKRHLFFKND--QWAWETLRDTVAPVVPDLSSDIDTSNFDDLEED----------KGEEETFPIPKAFVGNQLPFVGFTY 399
BLAST of Rho-associated protein kinase vs. Ensembl Human
Match: ROCK2 (Rho associated coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:10252]) HSP 1 Score: 365.925 bits (938), Expect = 1.024e-113 Identity = 181/405 (44.69%), Postives = 271/405 (66.91%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + + ++ D + I+++ L D +L LD L NK NF +++K+ +K+ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL FP D E+S A + + + DR VRLG+ +I+ H FF N +W WD I+++ +P +P L +D+D+S FD ED DV+T + ++ F+G + F GF+Y R Sbjct: 27 QRKLEALIRDPRSPINVESLLDGLNSLVLDL-DFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE-TGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNG-VEEIRQHPFFKND--QWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKA--------FVGNQLPFIGFTYYR 417
BLAST of Rho-associated protein kinase vs. Ensembl Human
Match: ROCK2 (Rho associated coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:10252]) HSP 1 Score: 388.652 bits (997), Expect = 6.466e-113 Identity = 181/405 (44.69%), Postives = 271/405 (66.91%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + + ++ D + I+++ L D +L LD L NK NF +++K+ +K+ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL FP D E+S A + + + DR VRLG+ +I+ H FF N +W WD I+++ +P +P L +D+D+S FD ED DV+T + ++ F+G + F GF+Y R Sbjct: 27 QRKLEALIRDPRSPINVESLLDGLNSLVLDL-DFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE-TGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRN-GVEEIRQHPFFKND--QWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKA--------FVGNQLPFIGFTYYR 417
BLAST of Rho-associated protein kinase vs. Ensembl Human
Match: CDC42BPB (CDC42 binding protein kinase beta [Source:HGNC Symbol;Acc:HGNC:1738]) HSP 1 Score: 336.65 bits (862), Expect = 3.056e-94 Identity = 177/434 (40.78%), Postives = 268/434 (61.75%), Query Frame = 3 Query: 51 VLLENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVC-FYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNT-KYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPD-DEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDV--DTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIINEDK 1337 +LL+ ++N + +S++ L D L+ +C S S L +KY F + K + + + ++ DF ++K+IG+GAFG+V +V+ K T ++A+KILNK +++ T ++EERD+++ D +WI LHYAFQD LY+VMDY GG+L+ +SK E L +D+ FY E+VLAI+ +H +VHRDIKPDN+L+D+ GHI+LADFGSC+KM+ V + A+GTPDYISPE+L + D KYG E DWW+LGV +YE+ YGE PFY+++L+ TYGKIM HE+ FP +VS A D +++LIC R RLGQ D K H FF W+ I++ +P+IP + + DTS FD +DDV +T L + T F G ++ F GF++ ++ + +++ SN + +D+ Sbjct: 13 LLLDGPWRN-----ESALSVETLLDVLVCLYTEC-SHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMND-DGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQN-GIEDFKKHAFFEG----LNWENIRNLEAPYIPDVSSPSDTSNFDV-DDDVLRNTEILPPGSH----TGFSGLHLPFIGFTFTT-ESCFSDRGSLKSIMQSNTLTKDE 428
BLAST of Rho-associated protein kinase vs. Ensembl Celegans
Match: let-502 (Rho-associated protein kinase let-502 [Source:UniProtKB/Swiss-Prot;Acc:P92199]) HSP 1 Score: 383.645 bits (984), Expect = 6.057e-113 Identity = 183/400 (45.75%), Postives = 265/400 (66.25%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 ++ ++ + D K I+++ L D+ L DCK + L K NF ++++V E L RMK +DF LK+IG+GAFG+V LVRH +T ++A+K+LNK ++ + F+ EERDIM +S WIV+L YAFQDP+ LYMVM+Y+PGG+LVN M+ EV EK FY AEIV A+ LH+ G++HRD+KPDN+LI I GHIKLADFG+CVKM+ V C+ A+GTPDYISPEVL +Q + ++GKEVDWW++GV +YE+ GE PFY++ L++TY IM H+ SL FP + +S A D +KK + RLG+ DI++H FF N EWT+ T+++++ P IP L++D DT++F ++++T + + TF G + F GF+Y Sbjct: 3 QDELRDQLVDPKSPINIESLLDTITALVNDCK-IPVLMRMKSVDNFISRYERVVESLAALRMKAADFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSEWIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSYEV-SEKWTRFYTAEIVEALAALHSMGYIHRDVKPDNMLISISGHIKLADFGTCVKMN-ANGVVRCSTAVGTPDYISPEVLRNQGQDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQAKDIIKKFLSAAPDRLGRN-SVDDIRNHKFFVND--EWTFATLREASPPVIPSLKSDDDTTHF----EEIETRDRDNAGDFQLPKTFNGNQLPFIGFTY 392
BLAST of Rho-associated protein kinase vs. Ensembl Celegans
Match: mrck-1 (Serine/threonine-protein kinase mrck-1 [Source:UniProtKB/Swiss-Prot;Acc:O01583]) HSP 1 Score: 352.443 bits (903), Expect = 4.548e-100 Identity = 184/409 (44.99%), Postives = 256/409 (62.59%), Query Frame = 3 Query: 57 LENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSK-VEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDN-TKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDE----VSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFG--EDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 LEN + + S E +S + L DS L+ +C + S L K F + K V K R+ DF +LK+IG+GAFG+V +VR + G+++A+KILNK ++V T ++EERD+++ D RWI LHYAFQD K LY VMDY GG+++ +SK V+ + E FY AE+VLAI+ LH G+VHRD+KPDN+L+D++GHI+LADFGSC+++ V N A+GTPDYISPE+L + D +YGKE DWW+LG+ +YE+ YG PFYS+ L++TYGKIM+H+ L F PDDE VS A D +++LIC VR G+ SD + H FF W+TI+DS P++P + + DTS FD EDD T L ++ F G ++ F GFSY Sbjct: 17 LENIYMDGPSKKPEALSFETLIDSLICLYDECCN-STLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRI-LADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDF-PDDEIDWVVSEEAKDLIRQLICSSDVRFGRN-GLSDFQLHPFFEGID----WNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDF-TPCLQETQPPRVLAAFTGNHLPFVGFSY 416
BLAST of Rho-associated protein kinase vs. Ensembl Celegans
Match: mrck-1 (Serine/threonine-protein kinase mrck-1 [Source:UniProtKB/Swiss-Prot;Acc:O01583]) HSP 1 Score: 352.443 bits (903), Expect = 4.548e-100 Identity = 184/409 (44.99%), Postives = 256/409 (62.59%), Query Frame = 3 Query: 57 LENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSK-VEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDN-TKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDE----VSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFG--EDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 LEN + + S E +S + L DS L+ +C + S L K F + K V K R+ DF +LK+IG+GAFG+V +VR + G+++A+KILNK ++V T ++EERD+++ D RWI LHYAFQD K LY VMDY GG+++ +SK V+ + E FY AE+VLAI+ LH G+VHRD+KPDN+L+D++GHI+LADFGSC+++ V N A+GTPDYISPE+L + D +YGKE DWW+LG+ +YE+ YG PFYS+ L++TYGKIM+H+ L F PDDE VS A D +++LIC VR G+ SD + H FF W+TI+DS P++P + + DTS FD EDD T L ++ F G ++ F GFSY Sbjct: 17 LENIYMDGPSKKPEALSFETLIDSLICLYDECCN-STLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRI-LADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDF-PDDEIDWVVSEEAKDLIRQLICSSDVRFGRN-GLSDFQLHPFFEGID----WNTIRDSNPPYVPEVSSPEDTSNFDVDVCEDDF-TPCLQETQPPRVLAAFTGNHLPFVGFSY 416
BLAST of Rho-associated protein kinase vs. Ensembl Celegans
Match: mrck-1 (Serine/threonine-protein kinase mrck-1 [Source:UniProtKB/Swiss-Prot;Acc:O01583]) HSP 1 Score: 349.747 bits (896), Expect = 3.193e-99 Identity = 182/408 (44.61%), Postives = 255/408 (62.50%), Query Frame = 3 Query: 57 LENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSK-VEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDN-TKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDE----VSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKS-TTFIGENIQFSGFSY 1259 LEN + + S E +S + L DS L+ +C + S L K F + K V K R+ DF +LK+IG+GAFG+V +VR + G+++A+KILNK ++V T ++EERD+++ D RWI LHYAFQD K LY VMDY GG+++ +SK V+ + E FY AE+VLAI+ LH G+VHRD+KPDN+L+D++GHI+LADFGSC+++ V N A+GTPDYISPE+L + D +YGKE DWW+LG+ +YE+ YG PFYS+ L++TYGKIM+H+ L F PDDE VS A D +++LIC VR G+ SD + H FF W+TI+DS P++P + + DTS FD D + +F Q + F G ++ F GFSY Sbjct: 17 LENIYMDGPSKKPEALSFETLIDSLICLYDECCN-STLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRI-LADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDF-PDDEIDWVVSEEAKDLIRQLICSSDVRFGRN-GLSDFQLHPFFEGID----WNTIRDSNPPYVPEVSSPEDTSNFDV--DVCEDDFTPCETQPPRVLAAFTGNHLPFVGFSY 414
BLAST of Rho-associated protein kinase vs. Ensembl Celegans
Match: mrck-1 (Serine/threonine-protein kinase mrck-1 [Source:UniProtKB/Swiss-Prot;Acc:O01583]) HSP 1 Score: 349.747 bits (896), Expect = 3.193e-99 Identity = 182/408 (44.61%), Postives = 255/408 (62.50%), Query Frame = 3 Query: 57 LENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSK-VEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDN-TKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDE----VSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKS-TTFIGENIQFSGFSY 1259 LEN + + S E +S + L DS L+ +C + S L K F + K V K R+ DF +LK+IG+GAFG+V +VR + G+++A+KILNK ++V T ++EERD+++ D RWI LHYAFQD K LY VMDY GG+++ +SK V+ + E FY AE+VLAI+ LH G+VHRD+KPDN+L+D++GHI+LADFGSC+++ V N A+GTPDYISPE+L + D +YGKE DWW+LG+ +YE+ YG PFYS+ L++TYGKIM+H+ L F PDDE VS A D +++LIC VR G+ SD + H FF W+TI+DS P++P + + DTS FD D + +F Q + F G ++ F GFSY Sbjct: 17 LENIYMDGPSKKPEALSFETLIDSLICLYDECCN-STLRKEKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRI-LADGSVASNVAVGTPDYISPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDF-PDDEIDWVVSEEAKDLIRQLICSSDVRFGRN-GLSDFQLHPFFEGID----WNTIRDSNPPYVPEVSSPEDTSNFDV--DVCEDDFTPCETQPPRVLAAFTGNHLPFVGFSY 414
BLAST of Rho-associated protein kinase vs. Ensembl Fly
Match: Rok (gene:FBgn0026181 transcript:FBtr0340152) HSP 1 Score: 366.311 bits (939), Expect = 1.534e-105 Identity = 175/399 (43.86%), Postives = 257/399 (64.41%), Query Frame = 3 Query: 63 NNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 N + + D ++D L D+ L DC S L K + ++K + ++ RM DF+ +K+IG GAFG+VQLVRHK + ++A+K L+K +++ + F+ EER IM +S WIV+LH+AFQD K LYMVMD++PGG++V+ M ++ EK FY E+VLA++ +HN GFVHRD+KPDN+L+D GH+KLADFG+C++M + V+ N A+GTPDYISPEVL SQ + +YG+E DWW++G+ LYE+ +GE PFY+D+L+ TYGKIM H+ SLSFPP+ E+S A ++ + DR+ RLG+ DIK+H FF N + W++D I++S P +P L +D DT F+ E D + +G F G ++ F GF+Y Sbjct: 23 NTLEREMRDPTSICNVDCLLDTVSALVSDCDHES-LRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIP-EKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSN-AVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRY-GIEDIKAHPFFRNDT--WSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKG-----FDGNHLPFIGFTY 410 HSP 2 Score: 51.2174 bits (121), Expect = 9.258e-6 Identity = 26/74 (35.14%), Postives = 42/74 (56.76%), Query Frame = 3 Query: 2949 NVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH-----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 N +N+ + W++++V + + + FY D+ + L LS + VRSV+ DVI A + EIPRIFQ+ Y Sbjct: 1144 NKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLY 1217
BLAST of Rho-associated protein kinase vs. Ensembl Fly
Match: Rok (gene:FBgn0026181 transcript:FBtr0340153) HSP 1 Score: 366.696 bits (940), Expect = 1.596e-105 Identity = 175/399 (43.86%), Postives = 257/399 (64.41%), Query Frame = 3 Query: 63 NNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 N + + D ++D L D+ L DC S L K + ++K + ++ RM DF+ +K+IG GAFG+VQLVRHK + ++A+K L+K +++ + F+ EER IM +S WIV+LH+AFQD K LYMVMD++PGG++V+ M ++ EK FY E+VLA++ +HN GFVHRD+KPDN+L+D GH+KLADFG+C++M + V+ N A+GTPDYISPEVL SQ + +YG+E DWW++G+ LYE+ +GE PFY+D+L+ TYGKIM H+ SLSFPP+ E+S A ++ + DR+ RLG+ DIK+H FF N + W++D I++S P +P L +D DT F+ E D + +G F G ++ F GF+Y Sbjct: 14 NTLEREMRDPTSICNVDCLLDTVSALVSDCDHES-LRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIP-EKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSN-AVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRY-GIEDIKAHPFFRNDT--WSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKG-----FDGNHLPFIGFTY 401 HSP 2 Score: 51.2174 bits (121), Expect = 9.188e-6 Identity = 26/74 (35.14%), Postives = 42/74 (56.76%), Query Frame = 3 Query: 2949 NVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH-----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 N +N+ + W++++V + + + FY D+ + L LS + VRSV+ DVI A + EIPRIFQ+ Y Sbjct: 1135 NKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLY 1208
BLAST of Rho-associated protein kinase vs. Ensembl Fly
Match: Rok (gene:FBgn0026181 transcript:FBtr0340151) HSP 1 Score: 366.311 bits (939), Expect = 1.674e-105 Identity = 175/399 (43.86%), Postives = 257/399 (64.41%), Query Frame = 3 Query: 63 NNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 N + + D ++D L D+ L DC S L K + ++K + ++ RM DF+ +K+IG GAFG+VQLVRHK + ++A+K L+K +++ + F+ EER IM +S WIV+LH+AFQD K LYMVMD++PGG++V+ M ++ EK FY E+VLA++ +HN GFVHRD+KPDN+L+D GH+KLADFG+C++M + V+ N A+GTPDYISPEVL SQ + +YG+E DWW++G+ LYE+ +GE PFY+D+L+ TYGKIM H+ SLSFPP+ E+S A ++ + DR+ RLG+ DIK+H FF N + W++D I++S P +P L +D DT F+ E D + +G F G ++ F GF+Y Sbjct: 23 NTLEREMRDPTSICNVDCLLDTVSALVSDCDHES-LRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIP-EKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSN-AVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRY-GIEDIKAHPFFRNDT--WSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKG-----FDGNHLPFIGFTY 410 HSP 2 Score: 51.2174 bits (121), Expect = 9.345e-6 Identity = 26/74 (35.14%), Postives = 42/74 (56.76%), Query Frame = 3 Query: 2949 NVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH-----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 N +N+ + W++++V + + + FY D+ + L LS + VRSV+ DVI A + EIPRIFQ+ Y Sbjct: 1135 NKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLY 1208
BLAST of Rho-associated protein kinase vs. Ensembl Fly
Match: Rok (gene:FBgn0026181 transcript:FBtr0074286) HSP 1 Score: 366.696 bits (940), Expect = 1.679e-105 Identity = 175/399 (43.86%), Postives = 257/399 (64.41%), Query Frame = 3 Query: 63 NNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 N + + D ++D L D+ L DC S L K + ++K + ++ RM DF+ +K+IG GAFG+VQLVRHK + ++A+K L+K +++ + F+ EER IM +S WIV+LH+AFQD K LYMVMD++PGG++V+ M ++ EK FY E+VLA++ +HN GFVHRD+KPDN+L+D GH+KLADFG+C++M + V+ N A+GTPDYISPEVL SQ + +YG+E DWW++G+ LYE+ +GE PFY+D+L+ TYGKIM H+ SLSFPP+ E+S A ++ + DR+ RLG+ DIK+H FF N + W++D I++S P +P L +D DT F+ E D + +G F G ++ F GF+Y Sbjct: 23 NTLEREMRDPTSICNVDCLLDTVSALVSDCDHES-LRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIP-EKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSN-AVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRY-GIEDIKAHPFFRNDT--WSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKG-----FDGNHLPFIGFTY 410 HSP 2 Score: 51.2174 bits (121), Expect = 9.198e-6 Identity = 26/74 (35.14%), Postives = 42/74 (56.76%), Query Frame = 3 Query: 2949 NVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH-----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 N +N+ + W++++V + + + FY D+ + L LS + VRSV+ DVI A + EIPRIFQ+ Y Sbjct: 1144 NKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLY 1217
BLAST of Rho-associated protein kinase vs. Ensembl Fly
Match: gek (gene:FBgn0023081 transcript:FBtr0072287) HSP 1 Score: 310.457 bits (794), Expect = 4.004e-86 Identity = 166/391 (42.46%), Postives = 241/391 (61.64%), Query Frame = 3 Query: 105 SLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVC-FYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNT-KYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDD----EVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 SLD L D+F L+ +C S S+L K ++F K K + R+ DF++LKIIG+GAFG+V +V+ T ++A+KILNK +++ T ++EERD+++ D +WI LHYAFQD LY+VMDY GG+L+ +SK E L +D+ FY E++LAIN +H +VHRDIKPDN+L+D +GH++LADFGSC+++D V N A+GTPDYISPE+L + D +YG E DWW+LGV +YE+ YGE PFY+++L+ TYGKIM H+ + P + +VS + D + KLIC RLGQ D H +F W I+ +P++P + + DTS FD ++DV L S + F G ++ F GF++ Sbjct: 50 SLDYLLDTFIVLYDEC-SNSSLRREKGVSDFLKLSKPFVHIVRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDK-DGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPENRLGQN-GIQDFMDHPWFVG----IDWKNIRQGPAPYVPEVSSPTDTSNFDVDDNDVR---LTDSIPPSANPAFSGFHLPFIGFTF 430
BLAST of Rho-associated protein kinase vs. Ensembl Zebrafish
Match: rock1 (Rho-associated, coiled-coil containing protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-100712-2]) HSP 1 Score: 385.185 bits (988), Expect = 4.925e-112 Identity = 182/399 (45.61%), Postives = 261/399 (65.41%), Query Frame = 3 Query: 78 VVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 ++ D K ++ D L DS L D L NK +F K++K K+ + RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + DR VRLG+ +IK H FF N +WTW+ I+++ +P +P L D DTS FD E+D +G + T F+G + F GF+Y Sbjct: 19 MLKDPKSEVNTDCLLDSLDALVYDL-DFPALRKNKSIDDFLKRYKDTISKIRELRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSNWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNK-DGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPEDSDISKDAKSLICAFLTDREVRLGRN-GVDEIKRHGFFKND--QWTWENIRETAAPVVPELSCDTDTSNFDDIEED----------RGEEETFPIPKAFVGNQLPFVGFTY 401
BLAST of Rho-associated protein kinase vs. Ensembl Zebrafish
Match: rock2a (rho-associated, coiled-coil containing protein kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030115-3]) HSP 1 Score: 381.333 bits (978), Expect = 1.599e-110 Identity = 193/434 (44.47%), Postives = 282/434 (64.98%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDD---VDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIINEDKLQSTNREN 1361 + ++ D + I+L+ L DS L LD L NK NF +++KV + + +M+ DF+ +K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM DS W+V+L AFQD + LYMVM+Y+PGG+LVN S +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV +YE+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S + + + DR VRLG++ +IK H FF N +WT+ TI+++ +P +P L +D+DTS FD E+D V+T F F+G + F GF+Y KEN+ N +NS+ + D S NRE+ Sbjct: 16 LEAMIKDPRSAINLESLLDSMNALVLDL-DFPALRKNKNIENFLNRYEKVMNHIRELQMRPEDFDRVKVIGRGAFGEVQLVRHKASQKVYAMKVLSKFEMIKRSDSAFFWEERDIMAFADSPWVVQLCCAFQDDRSLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDRYGHLKLADFGTCMKMDG-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPDDVEISQEGKNIICAFLTDREVRLGRS-GVEEIKRHPFFRND--QWTFSTIRETAAPVVPELSSDIDTSNFDEIEEDKGEVET-FPT-------PKAFVGNQLPFVGFTYF------KENQLL-NAVNSSAMKNDHPVS-NRED 427 HSP 2 Score: 56.6102 bits (135), Expect = 2.367e-7 Identity = 37/129 (28.68%), Postives = 59/129 (45.74%), Query Frame = 3 Query: 2868 STNLQNRNSKTESMTMDFRNINQILEVN--------VKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICYDKNDSLYLTAQMNPISKSTTS 3218 S N+Q+ +S + S D +LE+ V+N K+ WE+++V + + + FY + H L + L VRSV+ DV A + EIPRIFQI Y ++ P+ +S Sbjct: 1115 SLNVQSLDSASMSSGPDMDTDESLLEIRLEGWLSLPVRNNTKRFGWERKYVVVSSKKILFYNSEQDKEHSNPYMVLDIDKLFHVRSVTQTDVYRADAKEIPRIFQILYANEGESKKEQELEPLPGDKSS 1243
BLAST of Rho-associated protein kinase vs. Ensembl Zebrafish
Match: rock2a (rho-associated, coiled-coil containing protein kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030115-3]) HSP 1 Score: 380.948 bits (977), Expect = 1.691e-110 Identity = 190/431 (44.08%), Postives = 279/431 (64.73%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIINEDKLQSTNREN 1361 + ++ D + I+L+ L DS L LD L NK NF +++KV + + +M+ DF+ +K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM DS W+V+L AFQD + LYMVM+Y+PGG+LVN S +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV +YE+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S + + + DR VRLG++ +IK H FF N +WT+ TI+++ +P +P L +D+DTS FD E+D + F+G + F GF+Y KEN+ N +NS+ + D S NRE+ Sbjct: 16 LEAMIKDPRSAINLESLLDSMNALVLDL-DFPALRKNKNIENFLNRYEKVMNHIRELQMRPEDFDRVKVIGRGAFGEVQLVRHKASQKVYAMKVLSKFEMIKRSDSAFFWEERDIMAFADSPWVVQLCCAFQDDRSLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDRYGHLKLADFGTCMKMDG-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPDDVEISQEGKNIICAFLTDREVRLGRS-GVEEIKRHPFFRND--QWTFSTIRETAAPVVPELSSDIDTSNFDEIEEDK-----GEVETFPTPKAFVGNQLPFVGFTYF------KENQLL-NAVNSSAMKNDHPVS-NRED 427 HSP 2 Score: 56.6102 bits (135), Expect = 2.400e-7 Identity = 37/129 (28.68%), Postives = 59/129 (45.74%), Query Frame = 3 Query: 2868 STNLQNRNSKTESMTMDFRNINQILEVN--------VKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICYDKNDSLYLTAQMNPISKSTTS 3218 S N+Q+ +S + S D +LE+ V+N K+ WE+++V + + + FY + H L + L VRSV+ DV A + EIPRIFQI Y ++ P+ +S Sbjct: 1115 SLNVQSLDSASMSSGPDMDTDESLLEIRLEGWLSLPVRNNTKRFGWERKYVVVSSKKILFYNSEQDKEHSNPYMVLDIDKLFHVRSVTQTDVYRADAKEIPRIFQILYANEGESKKEQELEPLPGDKSS 1243
BLAST of Rho-associated protein kinase vs. Ensembl Zebrafish
Match: rock2b (rho-associated, coiled-coil containing protein kinase 2b [Source:ZFIN;Acc:ZDB-GENE-060125-2]) HSP 1 Score: 373.244 bits (957), Expect = 1.158e-107 Identity = 181/399 (45.36%), Postives = 261/399 (65.41%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + ++ + K ++L+ L DS L LD + L NK F +++K L + ++K DF+ +K+IG+GAFG VQLVRHK + ++A+K L+K ++V + F+ EERDIM S WIV+L AFQD K LY+VM+++PGG+LV S ++ E+ FY AE+VLA++ +H+ GF+HRDIKPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL+SQ YG+E DWW++GV +YE+ G+ PFYS++L+ TYGKIM H+ SL+FP D E+S A D + + R VRLG+T +IK H FF N +WT+DTI+D+ +P +P L +D+DTS FD DD+ + + + F G + F GF+Y R Sbjct: 16 LETLIKNQKSPLNLESLLDSVTALALDLNHPA-LRKNKNIDAFLSRYEKAVCNLKELQVKLDDFDRVKLIGRGAFGAVQLVRHKVSQQVYAMKQLSKFEMVKRSDSAFFWEERDIMAFSQSPWIVQLCCAFQDEKYLYLVMEFMPGGDLVTLTSNYDIP-EEWAQFYTAEVVLALDAIHSLGFIHRDIKPDNMLLDRNGHLKLADFGTCMKMDS-TGMVRCDTAVGTPDYISPEVLMSQGGTGYYGRECDWWSVGVFIYELLVGDTPFYSESLVGTYGKIMDHKNSLTFPDDIEMSKNAKDLICAFLSSREVRLGRT-GVDEIKCHPFFKND--QWTFDTIRDTMAPVVPELSSDIDTSNFD---DDIKDDPIG-TETFPPPRAFAGNQLPFVGFTYFR 404
BLAST of Rho-associated protein kinase vs. Ensembl Zebrafish
Match: rock2b (rho-associated, coiled-coil containing protein kinase 2b [Source:ZFIN;Acc:ZDB-GENE-060125-2]) HSP 1 Score: 373.244 bits (957), Expect = 1.238e-107 Identity = 181/399 (45.36%), Postives = 261/399 (65.41%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + ++ + K ++L+ L DS L LD + L NK F +++K L + ++K DF+ +K+IG+GAFG VQLVRHK + ++A+K L+K ++V + F+ EERDIM S WIV+L AFQD K LY+VM+++PGG+LV S ++ E+ FY AE+VLA++ +H+ GF+HRDIKPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL+SQ YG+E DWW++GV +YE+ G+ PFYS++L+ TYGKIM H+ SL+FP D E+S A D + + R VRLG+T +IK H FF N +WT+DTI+D+ +P +P L +D+DTS FD DD+ + + + F G + F GF+Y R Sbjct: 16 LETLIKNQKSPLNLESLLDSVTALALDLNHPA-LRKNKNIDAFLSRYEKAVCNLKELQVKLDDFDRVKLIGRGAFGAVQLVRHKVSQQVYAMKQLSKFEMVKRSDSAFFWEERDIMAFSQSPWIVQLCCAFQDEKYLYLVMEFMPGGDLVTLTSNYDIP-EEWAQFYTAEVVLALDAIHSLGFIHRDIKPDNMLLDRNGHLKLADFGTCMKMDS-TGMVRCDTAVGTPDYISPEVLMSQGGTGYYGRECDWWSVGVFIYELLVGDTPFYSESLVGTYGKIMDHKNSLTFPDDIEMSKNAKDLICAFLSSREVRLGRT-GVDEIKCHPFFKND--QWTFDTIRDTMAPVVPELSSDIDTSNFD---DDIKDDPIG-TETFPPPRAFAGNQLPFVGFTYFR 404
BLAST of Rho-associated protein kinase vs. Ensembl Xenopus
Match: med18 (mediator complex subunit 18 [Source:Xenbase;Acc:XB-GENE-1002158]) HSP 1 Score: 383.645 bits (984), Expect = 3.783e-111 Identity = 182/401 (45.39%), Postives = 263/401 (65.59%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVD--TNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + ++ D + I+++ L D ++ LD L NK NF +++K+ ++ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD K LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA+N +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S A + + + DR VRLG+ DIK H FF N +W WD I+++ +P +P L +D+DTS FD EDD F N F G + F GF+Y R Sbjct: 16 LEAILRDPRSPINVEGLLDGLNSIVLDL-DFPALRKNKNIDNFLNRYEKIVREVRKLQMKAEDYDVVKVIGRGAFGEVQLVRHKGSQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDEKHLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALNAIHSMGLIHRDVKPDNMLLDKYGHLKLADFGTCMKMDQ-TGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPEDVEISVHAKNLICAFLTDREVRLGRN-GIEDIKQHPFFKND--QWNWDNIRETVAPVVPELASDIDTSNFDDIEDDKGDAETFPN-------PKAFAGNQLPFIGFTYYR 403
BLAST of Rho-associated protein kinase vs. Ensembl Xenopus
Match: med18 (mediator complex subunit 18 [Source:Xenbase;Acc:XB-GENE-1002158]) HSP 1 Score: 383.259 bits (983), Expect = 8.709e-111 Identity = 182/401 (45.39%), Postives = 263/401 (65.59%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVD--TNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + ++ D + I+++ L D ++ LD L NK NF +++K+ ++ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD K LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA+N +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S A + + + DR VRLG+ DIK H FF N +W WD I+++ +P +P L +D+DTS FD EDD F N F G + F GF+Y R Sbjct: 16 LEAILRDPRSPINVEGLLDGLNSIVLDL-DFPALRKNKNIDNFLNRYEKIVREVRKLQMKAEDYDVVKVIGRGAFGEVQLVRHKGSQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDEKHLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALNAIHSMGLIHRDVKPDNMLLDKYGHLKLADFGTCMKMDQ-TGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPEDVEISVHAKNLICAFLTDREVRLGRN-GIEDIKQHPFFKND--QWNWDNIRETVAPVVPELASDIDTSNFDDIEDDKGDAETFPN-------PKAFAGNQLPFIGFTYYR 403
BLAST of Rho-associated protein kinase vs. Ensembl Xenopus
Match: med18 (mediator complex subunit 18 [Source:Xenbase;Acc:XB-GENE-1002158]) HSP 1 Score: 382.874 bits (982), Expect = 1.735e-110 Identity = 182/401 (45.39%), Postives = 263/401 (65.59%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVD--TNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + ++ D + I+++ L D ++ LD L NK NF +++K+ ++ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD K LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA+N +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S A + + + DR VRLG+ DIK H FF N +W WD I+++ +P +P L +D+DTS FD EDD F N F G + F GF+Y R Sbjct: 16 LEAILRDPRSPINVEGLLDGLNSIVLDL-DFPALRKNKNIDNFLNRYEKIVREVRKLQMKAEDYDVVKVIGRGAFGEVQLVRHKGSQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDEKHLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALNAIHSMGLIHRDVKPDNMLLDKYGHLKLADFGTCMKMDQ-TGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPEDVEISVHAKNLICAFLTDREVRLGRN-GIEDIKQHPFFKND--QWNWDNIRETVAPVVPELASDIDTSNFDDIEDDKGDAETFPN-------PKAFAGNQLPFIGFTYYR 403
BLAST of Rho-associated protein kinase vs. Ensembl Xenopus
Match: med18 (mediator complex subunit 18 [Source:Xenbase;Acc:XB-GENE-1002158]) HSP 1 Score: 379.793 bits (974), Expect = 5.384e-110 Identity = 186/412 (45.15%), Postives = 266/412 (64.56%), Query Frame = 3 Query: 36 KLNNYVLLENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVD--TNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 K+ NY++ + + +SD +I LDL F + L NK NF +++K+ ++ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD K LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA+N +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S A + + + DR VRLG+ DIK H FF N +W WD I+++ +P +P L +D+DTS FD EDD F N F G + F GF+Y R Sbjct: 8 KILNYLIKMESMGDGLSDGLNSIVLDLDFPA-------------LRKNKNIDNFLNRYEKIVREVRKLQMKAEDYDVVKVIGRGAFGEVQLVRHKGSQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDEKHLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALNAIHSMGLIHRDVKPDNMLLDKYGHLKLADFGTCMKMDQ-TGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPEDVEISVHAKNLICAFLTDREVRLGRN-GIEDIKQHPFFKND--QWNWDNIRETVAPVVPELASDIDTSNFDDIEDDKGDAETFPN-------PKAFAGNQLPFIGFTYYR 394
BLAST of Rho-associated protein kinase vs. Ensembl Xenopus
Match: ROCK1 (Rho-associated, coiled-coil containing protein kinase 1 [Source:NCBI gene;Acc:100496057]) HSP 1 Score: 377.096 bits (967), Expect = 2.962e-109 Identity = 171/365 (46.85%), Postives = 248/365 (67.95%), Query Frame = 3 Query: 75 NVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDD 1169 ++ D K ++ D L D + D + NK NF ++K K+ D RMK D+ ++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL+FP D ++S A + + + DR VRLG+ +IK H FF N +W W+T++D+ +P +P L +D+DTS FD E+D Sbjct: 16 GILRDPKSEVNTDCLLDGLDAMVYDL-DFPAMRKNKNIDNFLNRYKDTMSKVRDLRMKADDYEVVKVIGRGAFGEVQLVRHKSSRKVYAMKLLSKLEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNR-EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPEDSDISKEAKNLICAFLTDREVRLGRN-GVEEIKRHPFFKND--QWAWETLRDTVAPVVPDLTSDIDTSNFDDLEED 374
BLAST of Rho-associated protein kinase vs. Ensembl Mouse
Match: Rock1 (Rho-associated coiled-coil containing protein kinase 1 [Source:MGI Symbol;Acc:MGI:107927]) HSP 1 Score: 373.629 bits (958), Expect = 4.730e-116 Identity = 187/421 (44.42%), Postives = 272/421 (64.61%), Query Frame = 3 Query: 75 NVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNI 1322 N++ D K ++ D L D L D L NK NF ++K K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL+FP D+++S A + + + DR VRLG+ +IK H+FF N +W W+T++D+ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y + S+N +SN+ Sbjct: 16 NLLRDPKSEVNSDCLLDGLDALVYDL-DFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNK-EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNG-VEEIKRHLFFKND--QWAWETLRDTVAPVVPDLSSDIDTSNFDDLEED----------KGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANASENRSSSNV 420
BLAST of Rho-associated protein kinase vs. Ensembl Mouse
Match: Rock1 (Rho-associated coiled-coil containing protein kinase 1 [Source:MGI Symbol;Acc:MGI:107927]) HSP 1 Score: 390.193 bits (1001), Expect = 8.023e-114 Identity = 187/421 (44.42%), Postives = 272/421 (64.61%), Query Frame = 3 Query: 75 NVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNI 1322 N++ D K ++ D L D L D L NK NF ++K K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL+FP D+++S A + + + DR VRLG+ +IK H+FF N +W W+T++D+ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y + S+N +SN+ Sbjct: 16 NLLRDPKSEVNSDCLLDGLDALVYDL-DFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNK-EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRN-GVEEIKRHLFFKND--QWAWETLRDTVAPVVPDLSSDIDTSNFDDLEED----------KGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANASENRSSSNV 420
BLAST of Rho-associated protein kinase vs. Ensembl Mouse
Match: Rock2 (Rho-associated coiled-coil containing protein kinase 2 [Source:MGI Symbol;Acc:MGI:107926]) HSP 1 Score: 385.185 bits (988), Expect = 1.439e-111 Identity = 180/405 (44.44%), Postives = 270/405 (66.67%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + + ++ D + I+++ L D +L LD L NK NF +++K+ +K+ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL FP D E+S A + + + DR VRLG+ +IK H FF N +W WD I+++ +P +P L +D+D+S FD ED DV+T + ++ F+G + F GF+Y R Sbjct: 27 QRKLEALIRDPRSPINVESLLDGLNSLVLDL-DFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRN-GVEEIKQHPFFKND--QWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKA--------FVGNQLPFIGFTYFR 417 HSP 2 Score: 51.6026 bits (122), Expect = 9.462e-6 Identity = 31/92 (33.70%), Postives = 50/92 (54.35%), Query Frame = 3 Query: 2892 SKTESMTMDFRNINQILEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDV---QTCHFRLL-LSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 S +E ++ + R + L + V+N KK W K++V + + + FY + Q+ + +L + L VR V+ DV A + EIPRIFQI Y Sbjct: 1199 SSSEPISTESR-LEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILY 1289
BLAST of Rho-associated protein kinase vs. Ensembl Mouse
Match: Rock2 (Rho-associated coiled-coil containing protein kinase 2 [Source:MGI Symbol;Acc:MGI:107926]) HSP 1 Score: 384.415 bits (986), Expect = 1.589e-111 Identity = 180/405 (44.44%), Postives = 270/405 (66.67%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + + ++ D + I+++ L D +L LD L NK NF +++K+ +K+ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL FP D E+S A + + + DR VRLG+ +IK H FF N +W WD I+++ +P +P L +D+D+S FD ED DV+T + ++ F+G + F GF+Y R Sbjct: 27 QRKLEALIRDPRSPINVESLLDGLNSLVLDL-DFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRN-GVEEIKQHPFFKND--QWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKA--------FVGNQLPFIGFTYFR 417
BLAST of Rho-associated protein kinase vs. Ensembl Mouse
Match: Rock1 (Rho-associated coiled-coil containing protein kinase 1 [Source:MGI Symbol;Acc:MGI:107927]) HSP 1 Score: 370.933 bits (951), Expect = 8.189e-109 Identity = 166/344 (48.26%), Postives = 240/344 (69.77%), Query Frame = 3 Query: 243 MKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 MK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL+FP D+++S A + + + DR VRLG+ +IK H+FF N +W W+T++D+ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y Sbjct: 1 MKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVP-EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNK-EGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRN-GVEEIKRHLFFKND--QWAWETLRDTVAPVVPDLSSDIDTSNFDDLEED----------KGDEETFPIPKAFVGNQLPFVGFTY 329
BLAST of Rho-associated protein kinase vs. UniProt/SwissProt
Match: sp|O75116|ROCK2_HUMAN (Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4) HSP 1 Score: 388.267 bits (996), Expect = 4.366e-112 Identity = 181/405 (44.69%), Postives = 271/405 (66.91%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + + ++ D + I+++ L D +L LD L NK NF +++K+ +K+ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ SL FP D E+S A + + + DR VRLG+ +I+ H FF N +W WD I+++ +P +P L +D+D+S FD ED DV+T + ++ F+G + F GF+Y R Sbjct: 27 QRKLEALIRDPRSPINVESLLDGLNSLVLDL-DFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE-TGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRN-GVEEIRQHPFFKND--QWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKA--------FVGNQLPFIGFTYYR 417
BLAST of Rho-associated protein kinase vs. UniProt/SwissProt
Match: sp|A8WVU9|ROCK_CAEBR (Rho-associated protein kinase let-502 OS=Caenorhabditis briggsae OX=6238 GN=let-502 PE=3 SV=2) HSP 1 Score: 384.8 bits (987), Expect = 4.720e-112 Identity = 181/391 (46.29%), Postives = 263/391 (67.26%), Query Frame = 3 Query: 87 DDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 D K I+++ L D+ L DCK + L K NF +++++ E + RMK +DF LK+IG+GAFG+V LVRH +T ++A+K+LNK ++ + F+ EERDIM +S WIV+L YAFQDP+ LYMVM+Y+PGG+LVN M+ EV EK FY AEIV A+ LHN G++HRD+KPDN+LI GHIKLADFG+CVKM+ V C+ A+GTPDYISPEVL +Q ++++GKEVDWW++GV +YE+ GE PFY++ L++TY IM H+ SL FP + +S A D +KK + RLG+ + +I++H FF N EWT++T++D+T P +P L++D DT++F ++++T + ++ TF G + F GF+Y Sbjct: 12 DPKSPINIESLLDTITALVNDCK-IPVLMRMKSVDNFISRYERIVESVAALRMKATDFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSEWIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSYEV-SEKWTRFYTAEIVEALAALHNMGYIHRDVKPDNMLISRSGHIKLADFGTCVKMNS-NGVVRCSTAVGTPDYISPEVLRNQGKDSEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYANIMNHQTSLRFPDEPLISTQAKDIIKKFLSAAPERLGKN-NVDEIRNHKFFKND--EWTFETLKDATPPIVPSLKSDDDTTHF----EEIETRDRDNASDFQLPKTFNGNQLPFIGFTY 392
BLAST of Rho-associated protein kinase vs. UniProt/SwissProt
Match: sp|P92199|ROCK_CAEEL (Rho-associated protein kinase let-502 OS=Caenorhabditis elegans OX=6239 GN=let-502 PE=1 SV=1) HSP 1 Score: 383.645 bits (984), Expect = 7.705e-112 Identity = 183/400 (45.75%), Postives = 265/400 (66.25%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 ++ ++ + D K I+++ L D+ L DCK + L K NF ++++V E L RMK +DF LK+IG+GAFG+V LVRH +T ++A+K+LNK ++ + F+ EERDIM +S WIV+L YAFQDP+ LYMVM+Y+PGG+LVN M+ EV EK FY AEIV A+ LH+ G++HRD+KPDN+LI I GHIKLADFG+CVKM+ V C+ A+GTPDYISPEVL +Q + ++GKEVDWW++GV +YE+ GE PFY++ L++TY IM H+ SL FP + +S A D +KK + RLG+ DI++H FF N EWT+ T+++++ P IP L++D DT++F ++++T + + TF G + F GF+Y Sbjct: 3 QDELRDQLVDPKSPINIESLLDTITALVNDCK-IPVLMRMKSVDNFISRYERVVESLAALRMKAADFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHANSEWIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSYEV-SEKWTRFYTAEIVEALAALHSMGYIHRDVKPDNMLISISGHIKLADFGTCVKMN-ANGVVRCSTAVGTPDYISPEVLRNQGQDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQAKDIIKKFLSAAPDRLGRN-SVDDIRNHKFFVND--EWTFATLREASPPVIPSLKSDDDTTHF----EEIETRDRDNAGDFQLPKTFNGNQLPFIGFTY 392
BLAST of Rho-associated protein kinase vs. UniProt/SwissProt
Match: sp|M3TYT0|ROCK2_PIG (Rho-associated protein kinase 2 OS=Sus scrofa OX=9823 GN=ROCK2 PE=1 SV=1) HSP 1 Score: 386.341 bits (991), Expect = 2.466e-111 Identity = 181/405 (44.69%), Postives = 270/405 (66.67%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + + ++ D + I+++ L D +L LD L NK NF +++K+ +K+ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD K LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL FP D E+S A + + + DR VRLG+ +IK H FF N +W WD I+++ +P +P L +D+D+S FD ED DV+T + ++ F+G + F GF+Y R Sbjct: 27 QRKLEALIRDPRSPINVESLLDGLNSLVLDL-DFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRN-GVEEIKQHPFFKND--QWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKA--------FVGNQLPFIGFTYYR 417
BLAST of Rho-associated protein kinase vs. UniProt/SwissProt
Match: sp|P70336|ROCK2_MOUSE (Rho-associated protein kinase 2 OS=Mus musculus OX=10090 GN=Rock2 PE=1 SV=1) HSP 1 Score: 385.956 bits (990), Expect = 3.333e-111 Identity = 180/405 (44.44%), Postives = 270/405 (66.67%), Query Frame = 3 Query: 60 ENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + + ++ D + I+++ L D +L LD L NK NF +++K+ +K+ +MK D++++K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EERDIM +S W+V+L AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G +HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ SL FP D E+S A + + + DR VRLG+ +IK H FF N +W WD I+++ +P +P L +D+D+S FD ED DV+T + ++ F+G + F GF+Y R Sbjct: 27 QRKLEALIRDPRSPINVESLLDGLNSLVLDL-DFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDE-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRN-GVEEIKQHPFFKND--QWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKA--------FVGNQLPFIGFTYFR 417
BLAST of Rho-associated protein kinase vs. TrEMBL
Match: A0A3Q1HNI3 (Rho-associated, coiled-coil containing protein kinase 1 OS=Anabas testudineus OX=64144 PE=4 SV=1) HSP 1 Score: 396.741 bits (1018), Expect = 1.563e-114 Identity = 185/409 (45.23%), Postives = 267/409 (65.28%), Query Frame = 3 Query: 57 LENNFQNV---VSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 +E F+ + + D K ++ D L D L D L NK NF ++K+ K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L +AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + + DR VRLG+ +IK H FF N +WTW+ I+D+ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y Sbjct: 7 MEARFEKIDAMLKDPKSEVNTDCLLDGLDALVYDL-DFPALRKNKSIDNFLNRYKETISKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSSWVVQLFFAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMDK-DGMVRCDTAVGTPDYISPEVLKSQGGDGNYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPDDSDISNDAKNLICAFLTDREVRLGRN-GVDEIKRHPFFKND--QWTWENIRDTAAPVVPELASDIDTSNFDDIEED----------RGEEETFPIPKAFVGNQLPFVGFTY 399
BLAST of Rho-associated protein kinase vs. TrEMBL
Match: A0A1S3JNX4 (rho-associated protein kinase 2-like isoform X2 OS=Lingula unguis OX=7574 GN=LOC106174872 PE=3 SV=1) HSP 1 Score: 374.4 bits (960), Expect = 3.947e-114 Identity = 189/410 (46.10%), Postives = 270/410 (65.85%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKS 1298 + + D IS+D L DS +L DC + NK NF +++K+ + + RMK DF ++K+IG+GAFG+VQLVRH T ++A+K+L+K +++ + F+ EER+IM +S+WIV+LH+AFQD + LYMVMDY+PGG+LVN MS +V EK FY AE+VLA++ +H+ GFVHRD+KPDN+L+D +GH+KLADFG+C++MD V + A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TYGKIM H+ SLSFP D E+S A ++ + DRS RLGQ + +IK H FF + +WTWD+I+ + P +P L D+DTS F DD++ + Q + F G ++ F GF+Y R + E K S Sbjct: 17 LEGRMKDPNSEISVDGLLDSITSLVADC-DFPAIRRNKNVENFLGRYEKIVADVNNSRMKADDFEMVKVIGRGAFGEVQLVRHVSTRKVYAMKLLSKYEMIKRSDSAFFWEEREIMANANSQWIVQLHFAFQDHRFLYMVMDYMPGGDLVNLMSNYDV-PEKWAKFYCAEVVLALDAIHSMGFVHRDVKPDNMLLDAQGHLKLADFGTCMRMDK-DGMVRSDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYGKIMDHKNSLSFPEDIEISRDAKSLIRAFLTDRSERLGQ-RGVEEIKGHPFFTRND-QWTWDSIRKTVPPVVPELSCDVDTSNF----DDIEPDETAQETFPVPK-AFAGNHLPFIGFTYNRAYHLLSEAKAS 416
BLAST of Rho-associated protein kinase vs. TrEMBL
Match: A0A0S7LGB8 (ROCK1 OS=Poeciliopsis prolifica OX=188132 GN=ROCK1 PE=4 SV=1) HSP 1 Score: 379.793 bits (974), Expect = 5.353e-114 Identity = 187/409 (45.72%), Postives = 267/409 (65.28%), Query Frame = 3 Query: 57 LENNFQNV---VSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 +E F+ + + D K I+ D L D L D L NK NF ++KK K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L +AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ N YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + + DR VRLG+ +IK H FF N +WTWD I+++ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y Sbjct: 7 MEARFEKIDAMLQDPKSEINTDCLLDGLDALVYDL-DFPALRKNKSIDNFLNRYKKTISKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFFAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNE-DGMVQCDTAVGTPDYISPEVLKSQGGNGNYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPDDSDISNDAKNLICAFLTDREVRLGRN-GVDEIKRHPFFKND--QWTWDNIRETAAPVVPELSSDIDTSNFDDIEED----------RGEEETFPIPKAFVGNQLPFVGFTY 399
BLAST of Rho-associated protein kinase vs. TrEMBL
Match: A0A0S7LGC5 (ROCK1 OS=Poeciliopsis prolifica OX=188132 GN=ROCK1 PE=4 SV=1) HSP 1 Score: 377.481 bits (968), Expect = 1.011e-113 Identity = 187/409 (45.72%), Postives = 267/409 (65.28%), Query Frame = 3 Query: 57 LENNFQNV---VSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 +E F+ + + D K I+ D L D L D L NK NF ++KK K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L +AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ N YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + + DR VRLG+ +IK H FF N +WTWD I+++ +P +P L +D+DTS FD E+D +G + T F+G + F GF+Y Sbjct: 7 MEARFEKIDAMLQDPKSEINTDCLLDGLDALVYDL-DFPALRKNKSIDNFLNRYKKTISKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFFAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNE-DGMVQCDTAVGTPDYISPEVLKSQGGNGNYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPDDSDISNDAKNLICAFLTDREVRLGRN-GVDEIKRHPFFKND--QWTWDNIRETAAPVVPELSSDIDTSNFDDIEED----------RGEEETFPIPKAFVGNQLPFVGFTY 399
BLAST of Rho-associated protein kinase vs. TrEMBL
Match: A0A0S7LGC9 (ROCK1 OS=Poeciliopsis prolifica OX=188132 GN=ROCK1 PE=3 SV=1) HSP 1 Score: 370.933 bits (951), Expect = 7.647e-113 Identity = 185/404 (45.79%), Postives = 264/404 (65.35%), Query Frame = 3 Query: 57 LENNFQNV---VSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 +E F+ + + D K I+ D L D L D L NK NF ++KK K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L +AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ N YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + + DR VRLG+ +IK H FF N +WTWD I+++ +P +P L +D+DTS FD E+D + F+G + F GF+Y Sbjct: 7 MEARFEKIDAMLQDPKSEINTDCLLDGLDALVYDL-DFPALRKNKSIDNFLNRYKKTISKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFFAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNE-DGMVQCDTAVGTPDYISPEVLKSQGGNGNYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPDDSDISNDAKNLICAFLTDREVRLGRNG-VDEIKRHPFFKND--QWTWDNIRETAAPVVPELSSDIDTSNFDDIEED-----RGEEETFPIPKAFVGNQLPFVGFTY 399
BLAST of Rho-associated protein kinase vs. Ensembl Cavefish
Match: rock2a (rho-associated protein kinase 2 [Source:NCBI gene;Acc:103042784]) HSP 1 Score: 381.719 bits (979), Expect = 7.389e-111 Identity = 180/400 (45.00%), Postives = 264/400 (66.00%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFD-FGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + ++ D + I+L+ L D+ L LD L NK F +++KV + + +MK DF+ +K+IG+GAFG+VQLVRH+ + ++A+K+L+K +++ + F+ EERDIM DS W+V+L AFQD + LYMVM+Y+PGG+LVN S +V EK FY AE+V+A++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV ++E+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S A + + + DR VRLG+ +IKSH FF N +WT+DTI+D+ +P +P L +D+DTS FD ED D F+G + F GF+Y + Sbjct: 16 LEAMIRDPRSAINLESLLDAVNALVLDL-DFPALRKNKNIETFLNRYEKVMNHIRELQMKPEDFDRVKVIGRGAFGEVQLVRHRASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFADSPWVVQLCCAFQDDRYLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVMALDAIHSMGFIHRDVKPDNMLLDRNGHLKLADFGTCMKMDS-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFIFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPDDVEISKEAKNIICAFLTDREVRLGRN-GVGEIKSHPFFKND--QWTFDTIRDTAAPVVPELSSDIDTSNFDEIEEDKGDVETFPTPK------AFVGNQLPFVGFTYFK 403 HSP 2 Score: 55.4546 bits (132), Expect = 4.815e-7 Identity = 28/76 (36.84%), Postives = 41/76 (53.95%), Query Frame = 3 Query: 2940 LEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 L + V+N K+ WE+++V + + + FY + H L + L VRSV+ DV A + EIPRIFQI Y Sbjct: 1143 LSLPVRNNTKRFGWERKYVVVSSKKILFYNSEQDKEHSNPYMVLDIDKLFHVRSVTQTDVYRADAKEIPRIFQILY 1218
BLAST of Rho-associated protein kinase vs. Ensembl Cavefish
Match: ROCK1 (Rho associated coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:10251]) HSP 1 Score: 354.369 bits (908), Expect = 2.539e-110 Identity = 175/364 (48.08%), Postives = 246/364 (67.58%), Query Frame = 3 Query: 168 LPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 L NK NF + + V K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + DR VRLG+ +IK H FF N +WTWD I+D+ +P +P L +D+DTS FD E+D + F+G + F GF+Y Sbjct: 31 LRKNKSIDNFLSRCECV--KIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSSWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHAMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNK-DGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPEDSDISKDAKSLICAFLTDREVRLGRNG-VDEIKRHSFFKND--QWTWDNIRDTAAPVVPELSSDIDTSNFDDIEED-----RGEEETFPIPKAFVGNQLPFVGFTY 382
BLAST of Rho-associated protein kinase vs. Ensembl Cavefish
Match: rock2a (rho-associated protein kinase 2 [Source:NCBI gene;Acc:103042784]) HSP 1 Score: 380.563 bits (976), Expect = 5.041e-110 Identity = 180/400 (45.00%), Postives = 264/400 (66.00%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFD-FGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + ++ D + I+L+ L D+ L LD L NK F +++KV + + +MK DF+ +K+IG+GAFG+VQLVRH+ + ++A+K+L+K +++ + F+ EERDIM DS W+V+L AFQD + LYMVM+Y+PGG+LVN S +V EK FY AE+V+A++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV ++E+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S A + + + DR VRLG+ +IKSH FF N +WT+DTI+D+ +P +P L +D+DTS FD ED D F+G + F GF+Y + Sbjct: 16 LEAMIRDPRSAINLESLLDAVNALVLDL-DFPALRKNKNIETFLNRYEKVMNHIRELQMKPEDFDRVKVIGRGAFGEVQLVRHRASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFADSPWVVQLCCAFQDDRYLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVMALDAIHSMGFIHRDVKPDNMLLDRNGHLKLADFGTCMKMDS-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFIFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPDDVEISKEAKNIICAFLTDREVRLGRN-GVGEIKSHPFFKND--QWTFDTIRDTAAPVVPELSSDIDTSNFDEIEEDKGDVETFPTPK------AFVGNQLPFVGFTYFK 403 HSP 2 Score: 55.0694 bits (131), Expect = 6.219e-7 Identity = 28/76 (36.84%), Postives = 41/76 (53.95%), Query Frame = 3 Query: 2940 LEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 L + V+N K+ WE+++V + + + FY + H L + L VRSV+ DV A + EIPRIFQI Y Sbjct: 1143 LSLPVRNNTKRFGWERKYVVVSSKKILFYNSEQDKEHSNPYMVLDIDKLFHVRSVTQTDVYRADAKEIPRIFQILY 1218
BLAST of Rho-associated protein kinase vs. Ensembl Cavefish
Match: rock2b (rho-associated, coiled-coil containing protein kinase 2b [Source:ZFIN;Acc:ZDB-GENE-060125-2]) HSP 1 Score: 367.081 bits (941), Expect = 3.884e-106 Identity = 185/434 (42.63%), Postives = 276/434 (63.59%), Query Frame = 3 Query: 63 NNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIINEDKLQSTNR 1355 + ++ + + ++L+ L DS L LD + L NK F +++K +L + + + DF+ +K+IG+GA+G VQLVRHK + ++A+K L+K +++ + F+ EERDIM +S WIV+L AFQD + LY+VM+++PGG+LV + + EK FY AE+V+A++ +H+ GF+HRDIKPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL+SQ YG+E DWW++GV LYE+ G+ PFY+++L+ TYGKIM H+ SL+FP D E+S A + + DR VRLG+T +IK H FF N +WT+DTI+D+ +P +P L +D+DTS+FD ED DV+T + F+G + F GF+Y R EN K + + I + +L+S R Sbjct: 14 RKLEALIREQRSALNLESLLDSVNALALDLNHPA-LRKNKNIDAFLSRYEKAVSRLRELQARLDDFDRIKLIGRGAYGAVQLVRHKVSKQVYAMKQLSKFEMIKRSDSAFFWEERDIMAFSNSPWIVQLCCAFQDERHLYLVMEFMPGGDLVTLTMNYD-MPEKWARFYTAEVVMALDAIHSLGFIHRDIKPDNMLLDRTGHLKLADFGTCMKMDK-TGMVRCDTAVGTPDYISPEVLMSQGGTGYYGRECDWWSVGVFLYELLVGDTPFYAESLVGTYGKIMDHKNSLTFPDDVEMSKEAKSLICAFLTDREVRLGRT-GVEEIKCHPFFKND--QWTFDTIRDTMAPVVPELNSDIDTSHFDDIEDEKGDVET--------FPPARAFVGNQLPFVGFTYFR------ENHKLEEKFKNEIQVKGELESKCR 427 HSP 2 Score: 51.9878 bits (123), Expect = 5.665e-6 Identity = 28/68 (41.18%), Postives = 40/68 (58.82%), Query Frame = 3 Query: 2967 KKMSWEKRFVRLEEQNLCFYG--ED-VQTCHFRLL-LSSLIFVRSVSNVDVIHAKSSEIPRIFQICYD 3158 K+ W+K++V + + + FY ED Q+ F +L + L VR V+ DV A + EIPRIFQI YD Sbjct: 1061 KRFGWDKKYVVMSSKKILFYDSEEDREQSNPFMILDIDKLFHVRPVTQTDVYRADAREIPRIFQILYD 1128
BLAST of Rho-associated protein kinase vs. Ensembl Cavefish
Match: rock2a (rho-associated protein kinase 2 [Source:NCBI gene;Acc:103042784]) HSP 1 Score: 363.999 bits (933), Expect = 7.572e-105 Identity = 166/345 (48.12%), Postives = 239/345 (69.28%), Query Frame = 3 Query: 234 DFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFD-FGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 + +MK DF+ +K+IG+GAFG+VQLVRH+ + ++A+K+L+K +++ + F+ EERDIM DS W+V+L AFQD + LYMVM+Y+PGG+LVN S +V EK FY AE+V+A++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V+C+ A+GTPDYISPEVL SQ + YG+E DWW++GV ++E+ G+ PFY+D+L+ TY KIM H+ SL+FP D E+S A + + + DR VRLG+ +IKSH FF N +WT+DTI+D+ +P +P L +D+DTS FD ED D F+G + F GF+Y + Sbjct: 6 ELQMKPEDFDRVKVIGRGAFGEVQLVRHRASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFADSPWVVQLCCAFQDDRYLYMVMEYMPGGDLVNLTSTYDVP-EKWAKFYTAEVVMALDAIHSMGFIHRDVKPDNMLLDRNGHLKLADFGTCMKMDS-TGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFIFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPDDVEISKEAKNIICAFLTDREVRLGRN-GVGEIKSHPFFKND--QWTFDTIRDTAAPVVPELSSDIDTSNFDEIEEDKGDVETFPTPK------AFVGNQLPFVGFTYFK 339 HSP 2 Score: 55.4546 bits (132), Expect = 4.789e-7 Identity = 28/76 (36.84%), Postives = 41/76 (53.95%), Query Frame = 3 Query: 2940 LEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCH----FRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 L + V+N K+ WE+++V + + + FY + H L + L VRSV+ DV A + EIPRIFQI Y Sbjct: 1079 LSLPVRNNTKRFGWERKYVVVSSKKILFYNSEQDKEHSNPYMVLDIDKLFHVRSVTQTDVYRADAKEIPRIFQILY 1154
BLAST of Rho-associated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004595.1 (pep scaffold:Pmarinus_7.0:GL477044:11103:63873:-1 gene:ENSPMAG00000004137.1 transcript:ENSPMAT00000004595.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 369.777 bits (948), Expect = 2.116e-107 Identity = 175/385 (45.45%), Postives = 257/385 (66.75%), Query Frame = 3 Query: 117 LFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDD--VDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 L D L LD L NK +F +++ + K+ D RM+ D++ +K+IG+GAFG+VQLVRHK T ++A+K+LNK +++ + F+ EERDIM +S WIV+L Y+FQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ G++HRD+KPDN+L+D GH+KLADFG+C+K++ V C+ A+GTPDYISPEVL SQ YG+E DWW++GV L+E+ G+ PFY+++L+ TYGKIM H++SL+FP D ++S A + + +R VRLG+ A +IK H FF N +WTW+ I+++++P +P L +D DTS FD E+D D F + F+G + F GF+Y + Sbjct: 1 LQDGLYALVLDL-DFPALRKNKNVESFLQRYGEAVGKVRDLRMRADDYDSVKVIGRGAFGEVQLVRHKVTKSVYAMKLLNKLEMIKRSDSAFFWEERDIMAFANSPWIVQLFYSFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLAVDAIHSMGYIHRDVKPDNMLLDKSGHLKLADFGTCMKLNK-DGMVRCDTAVGTPDYISPEVLRSQGGQGYYGRECDWWSVGVFLFEMLVGDTPFYAESLVGTYGKIMDHKKSLTFPVDLDISKNAKSLICAFLTERDVRLGKNGFA-EIKCHDFFKND--QWTWENIRETSAPVVPELSSDTDTSNFDEIENDKSADETF-------PQPKAFVGNQLPFVGFTYYK 372
BLAST of Rho-associated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003561.1 (pep scaffold:Pmarinus_7.0:GL478057:5187:43749:1 gene:ENSPMAG00000003167.1 transcript:ENSPMAT00000003561.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 363.229 bits (931), Expect = 4.804e-105 Identity = 177/401 (44.14%), Postives = 260/401 (64.84%), Query Frame = 3 Query: 63 NNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDV--DTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 + +V D + ++ + L S +N + NK NF +++K K+ D RM+ +D++++K+IG+GAFG+VQLVRHK T ++A+K+L+K ++ + F+ EERDIM +S W+V+L YAFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV LYE+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + + DR VR+G+ +IK H FF N +WTW+ I+++ +P +P L +D DTS FD E+D D F F G + F GF+Y Sbjct: 12 GRLEGMVKDPRSEVNAEGLL-SRKNPLVAPSGFPAFFRNKNIDNFLNRYEKAVGKVRDLRMRANDYDVVKVIGRGAFGEVQLVRHKATKKVYAMKLLSKFEMTKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDHRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKNGHLKLADFGTCMKMD-TEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNALNFPDDVDISKDAKNLICAFLIDREVRVGRN-GVGEIKRHPFFKND--QWTWENIRETAAPVVPELVSDTDTSNFDEIEEDKAEDETFPV-------PKAFSGNQLPFVGFTY 399 HSP 2 Score: 51.6026 bits (122), Expect = 1.549e-6 Identity = 27/76 (35.53%), Postives = 43/76 (56.58%), Query Frame = 3 Query: 2940 LEVNVKNKGKKMSWEKRFVRLEEQNLCFYGED----VQTCHFRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 L V KN K+ W+K++V + + + FY ++ + T + L + L VR V+ DV A++ +IPRIFQI Y Sbjct: 1148 LSVPNKNNIKRYGWKKQYVVVSSKKILFYNDEQDKELSTPYMVLDIDKLFHVRPVTQGDVYRAEAKDIPRIFQILY 1223
BLAST of Rho-associated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006413.1 (pep scaffold:Pmarinus_7.0:GL485553:3974:11158:-1 gene:ENSPMAG00000005799.1 transcript:ENSPMAT00000006413.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 310.071 bits (793), Expect = 9.943e-96 Identity = 164/350 (46.86%), Postives = 220/350 (62.86%), Query Frame = 3 Query: 210 KKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSY 1259 +K K+ D RM DF LLK+IG+GAFG VQLVRHKQT + A+K LNK +++ + F+ EERDIM +S WI++L AFQD + LYMVM+Y+PGG+LV+ MS +V EK FY AE+VLA++ +H+ GF+HRDIKPDN+L+D GH+KLADFG+C+KMD V N A+GTPDYISPEVL SQ + YG + +G L G+ PFY+++L+ TY KIM H SL FP D VS A + + DR VRLG+T +IK H FF N +WTW I+++ +P +P L +D D S F DD+ + F+G + F GF+Y Sbjct: 1 EKAVGKVHDLRMNVHDFELLKVIGRGAFGVVQLVRHKQTRRVHAMKRLNKGEMLKRSDSAFFWEERDIMAFANSSWIIQLFSAFQDERYLYMVMEYMPGGDLVSLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDIKPDNMLLDRLGHLKLADFGTCMKMD-AEGMVRSNTAVGTPDYISPEVLKSQGGDGYYGLH-EPPEIGNHLVAAHAGDTPFYAESLVGTYSKIMDHRNSLCFPDDASVSKEARSLICAFLTDREVRLGRT-GVDEIKRHPFFRND--QWTWQNIRETVAPVVPELASDADASCF----DDISEQEKAEEEAFSVPKAFLGNQLPFIGFTY 340
BLAST of Rho-associated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002084.1 (pep scaffold:Pmarinus_7.0:GL476486:6827:40506:-1 gene:ENSPMAG00000001890.1 transcript:ENSPMAT00000002084.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 315.849 bits (808), Expect = 7.769e-94 Identity = 156/350 (44.57%), Postives = 228/350 (65.14%), Query Frame = 3 Query: 225 KLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVC-FYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNT-KYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDD-EVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQ--GLKSTTFIGENIQFSGFSY 1259 ++ + R+ DF +LK+IG+GAFG+V +V+ K + +FA+KILNK +++ T ++EERD++++ DS+WI LHYAFQD LY+VMDY GG+L+ +SK E L +++ FY AE+VLAI+ +H +VHRDIKPDN+L+D+ GHI+LADFGSC+K+ V + A+GTPDYISPE+L + D KYG E DWW+LGV +YE+ +GE PFY+++L+ TYGKIM H++ FP + EVS D ++ LIC R R G+ D K+H FF WD I++ +P+IP + + DTS F DVD ++L + T F G ++ F GF++ Sbjct: 7 RVKEMRLHREDFEMLKVIGRGAFGEVAVVKLKSSEKVFAMKILNKWEMLKRAETACFREERDVLVRGDSQWITTLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPEEMAKFYVAEMVLAIHSIHELKYVHRDIKPDNVLLDMNGHIRLADFGSCLKL-LTDGTVQSSVAVGTPDYISPEILQAMEDGKGKYGPECDWWSLGVCMYEMLFGETPFYAESLVETYGKIMNHKERFQFPTNSVEVSDDGKDLIRHLICSREQRFGRN-GIQDFKNHPFFAG----IDWDNIRNCEAPYIPEVSSPTDTSNF-----DVDDDYLKNTEAVPPPSHTAFSGLHLPFVGFTF 345
BLAST of Rho-associated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005559.1 (pep scaffold:Pmarinus_7.0:GL476474:6865:57025:1 gene:ENSPMAG00000004999.1 transcript:ENSPMAT00000005559.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 282.337 bits (721), Expect = 1.601e-77 Identity = 164/446 (36.77%), Postives = 245/446 (54.93%), Query Frame = 3 Query: 42 NNYVLLENNFQNVVSDDKENISL---DLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLL-EKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIIN---EDKLQSTNRE 1358 + ++ L FQ ++ ++ L D L DS LF +C S L + + NF +H + +L + R+ SDF + ++ +G +VQ+VR + TGD++A+K+L KS ++ + ++EERD++ + S W+ L YAFQD LY+VM+Y PGG+L+ + + E L E V FY AE+VLA LH G+VHRD+KP+N+L+D GHIKLADFGS K++ K V+ G+PDYI+PEVL S S YG E DWW++GV+ YE+ YG+ PF T I ++ + FP + VS +D +K L+C R RL K + H FF W+ IQ PF+P L+ D DTS F+ E + + + + L+ F G N+ F GFSY + + +VL+S N E KLQ+ +E Sbjct: 22 SRFLRLNQLFQGKIAQPGQHRYLATRDGLLDSLLVLFEEC-SDPGLMKHNHIANFVSKHAETVSELQELRVTSSDFEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPWLTHLQYAFQDEDNLYLVMEYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMGYVHRDLKPENVLVDRTGHIKLADFGSAAKLN-ANKMVSSKLPEGSPDYIAPEVLSSFSGKGSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDLVKGLLCGRVDRLTPDK----LLCHPFFAG----IDWNNIQHMPPPFVPPLQGDDDTSNFE--EVERERPAAPPTPRQLRQPGFSGNNLPFIGFSYSKALVGLSRTESVMSVLDSPAKNSSIEKKLQTKAKE 455
BLAST of Rho-associated protein kinase vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 203.371 bits (516), Expect = 9.807e-58 Identity = 119/306 (38.89%), Postives = 176/306 (57.52%), Query Frame = 3 Query: 252 SDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLIC-DRSVRLGQTKDAS-DIKSHIFFNNSSREWTWDTIQDS--TSPF-IPVLENDLDTSYFD 1154 SDF +L+ +G G+FG+V L+R G +ALK L K +V + +ER ++ + +I+++ FQD ++++MVMDY+ GG L + + K + FYAAE+ LA+ LH+ ++RD+KP+NIL+D GHIK+ DFG K P Y C GTPDYI+PEV+ ++ Y K VDWW+ GV++YE+ G PFY+ N + TY I+ E L FPP A D +KKLI D S RLG ++ S D+K+H +FN E W+ + +P+ P+ + DTS FD Sbjct: 86 SDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFG-FAKYVPDVTYTLC----GTPDYIAPEVVSTKP----YNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAE--LKFPPFFHPD--AQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFN----EVIWEKLLARYIETPYEPPIQQGQGDTSQFD 374
BLAST of Rho-associated protein kinase vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 202.986 bits (515), Expect = 1.570e-57 Identity = 117/320 (36.56%), Postives = 190/320 (59.38%), Query Frame = 3 Query: 246 KYS--DFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPP--DDEVSGMALDFMKKLIC-DRSVRLGQTKDAS-DIKSHIFFNNSSREWTWDTI--QDSTSPF-IPVLENDLDTSYFD-FGEDDVD 1175 KYS DF +L+ +G G+FG+V L+R + G +A+K+L K VV + +ER ++ + +I+++ FQD ++++M+MDY+ GG L + + K + FYAAE+ LA+ LH+ ++RD+KP+NIL+D GHIK+ DFG K P Y C GTPDYI+PEV+ ++ Y K +DWW+ G+++YE+ G PFY N + TY KI+ E L FPP +++V D + +LI D S RLG ++ + D+K+H +F +E W+ + ++ +P+ P+ + DTS FD + E+D++ Sbjct: 81 KYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFG-FAKYVPDVTYTLC----GTPDYIAPEVVSTKP----YNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAE--LRFPPFFNEDVK----DLLSRLITRDLSQRLGNLQNGTEDVKNHPWF----KEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDIN 381
BLAST of Rho-associated protein kinase vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]) HSP 1 Score: 208.379 bits (529), Expect = 6.617e-57 Identity = 144/438 (32.88%), Postives = 235/438 (53.65%), Query Frame = 3 Query: 24 DKMDKLNNYVLLENNFQNVVSDDKE---------NISLDLLFDSFQ---NLFLDCKSVSNLPTNKYFTNFYKQHKKV-----YEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVT-CEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLIC-DRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFD--FGE----DDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYI 1262 D ++ + +L N+Q + + E N + D+ DSF NL +D + L N ++ + + + K+ Y+ + + DF+LLK+IG+G+FG+V VR K T ++ALK L K+ +V+ CE T ER ++ ++D +IV L ++FQ P++LY+V+ ++ GG L + FY AE++ A++ LH ++RD+KP+NIL+D +GHI L DFG C K++ + + GTP+Y++PE+LL Q Y K VDWW LG++LYE+ G PP+Y +N+ Y KI+ +Q L FP D A D + L+ D S RLG +I++H FF + S W ++ P+ P++++++DT+ FD F + D V +L+ S Q QF G++YI Sbjct: 250 DVFARIPSLLLPSKNWQQEIGEQDEVLKEILKKINTNQDIHLDSFHLPLNLKIDSAAQIRL-YNHHWISLERGYGKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVT-HTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLC-KLN-MKDNDKTDTFCGTPEYLAPEILLGQG----YTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKIL--QQPLLFP--DGFDPAAKDLLIGLLSRDPSRRLG-VNGTDEIRNHPFFKDIS--WKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLSASIQK-----------QFGGWTYI 661
BLAST of Rho-associated protein kinase vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 200.29 bits (508), Expect = 9.043e-57 Identity = 114/313 (36.42%), Postives = 185/313 (59.11%), Query Frame = 3 Query: 255 DFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLI-CDRSVRLGQTKDAS-DIKSHIFFNNSSREWTWDTI--QDSTSPFIPVLENDL-DTSYFD-FGEDDVD 1175 DF +++ +G G+FG+V LVR G +A+K+L K QVV + +ER ++ ++ +++++ FQD + ++MVMDY+ GG L + + K + FYAAE++LA+ LH ++RD+KP+NIL+D GHIK+ DFG ++ VT + C GTPDYI+PEV+ ++ Y K VDWW+LGV++YE+ G PFY + TY KI+ + + +PP +D + KLI D + R+G + S DIK+H +F+ E W+ + +D +P+ P + + + DTS FD + E+ +D Sbjct: 69 DFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVT-WTLC----GTPDYIAPEVITTKP----YNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKIL--QGKVVYPP--YFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFS----EVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLD 364
BLAST of Rho-associated protein kinase vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]) HSP 1 Score: 204.527 bits (519), Expect = 1.681e-55 Identity = 127/346 (36.71%), Postives = 192/346 (55.49%), Query Frame = 3 Query: 255 DFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSC---VKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLIC-DRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFD--FGE----DDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYI 1262 DF+LLK+IG+G+FG+V VR K T ++ALK + KS +V+ ER ++ ++D +IV L ++FQ P++LY V+ ++ GG L + K FY AE++ A++ LH V+RD+KP+NIL+D +GHI L DFG C +K D T + GTP+Y++PE+LL Y K VDWW LGV+LYE+ G PP+Y +++ Y KI+ ++ L FP D A D + L+ D + RLG A +I++H FF+ S W ++ P+ P + N +DTS FD F D V +L++S Q QF G++Y+ Sbjct: 346 DFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKT-----DTFCGTPEYLAPELLLGLG----YTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKIL--QEPLVFP--DGFDRDAKDLLIGLLSRDPTRRLGYN-GADEIRNHPFFSQLS--WKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSESVQK-----------QFGGWTYV 664
BLAST of Rho-associated protein kinase vs. Ensembl Nematostella
Match: EDO37677 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF23]) HSP 1 Score: 296.204 bits (757), Expect = 1.640e-89 Identity = 161/391 (41.18%), Postives = 241/391 (61.64%), Query Frame = 3 Query: 102 ISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVC-FYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQ-SDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVD-TNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 +S + L D+F LF +C S +K F K+++ + +L + +DFN++ IG+G FG+VQ+V+ K TGD++A+K L KSQ ++ E F++EER+IM ++ WI L YAFQD LY+VMDY PGG+L++ +SK + + E+D+ FY AEIV+AI+ LH GFVHRD+KPDN+LID GHIKLADFGS ++ K V +GTP+YI+PEVL S YG E DWW+LGV+ YE+ +G+ PF +D+++ TY KIM + SL FP + ++S A + + L+ R+G + H FFN W+ +Q++ P++P L+ DTS FD E D D + L + + + F G+++ F GFS+I+ Sbjct: 30 VSREALLDAFTVLFEECSSDHMKKKDKNIATFVKKYQPMINELRRLSLSKNDFNVVNTIGRGHFGEVQVVKDKATGDVYAMKTLKKSQTLSEEAVAFFEEEREIMATANNPWITSLQYAFQDSHSLYLVMDYHPGGDLLSLLSKYDDIFEEDMARFYLAEIVMAIHSLHTMGFVHRDVKPDNVLIDRTGHIKLADFGSSARLS-ADKKVFSKMPVGTPEYIAPEVLTSMDGSGGAYGVECDWWSLGVVAYEMLFGQTPFEADSVVVTYSKIMNFKSSLRFPSEPKISEDAKELIHNLLTSSEGRIGY----EGLGCHKFFNGIE----WNKLQNTLPPYVPTLDGTDDTSNFDEFEPDSDEMDQLKKYSFCSEEKGFKGKDLPFVGFSFIK 411
BLAST of Rho-associated protein kinase vs. Ensembl Nematostella
Match: EDO32008 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW88]) HSP 1 Score: 282.337 bits (721), Expect = 1.760e-86 Identity = 137/277 (49.46%), Postives = 191/277 (68.95%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTY 899 +N+V D + + +D L D + L DC + L NK NF +++++ + R+ DF LK+IG+GAFG+VQLVRH T ++A+K+L+K +++ + F+ EER+IM +S WIVKLHYAFQD K LYMVMDY+ GG+LVN MS E+ EK FY AE+VLA++ +H GFVHRD+KPDN+L+D +GH+KLADFG+C++MD V + A+GTPDYISPEVL SQ YG+E DWW++GV LYE+ G+ PFY+D+L+ TY Sbjct: 5 LENIVRDSRSPLYVDGLLDGIEALVNDC-NFPQLRRNKNVENFLQRYEQPTRVIQTHRLNNDDFKTLKVIGRGAFGEVQLVRHTHTKKVYAMKLLSKFEMIKRSDSAFFWEEREIMAHSNSNWIVKLHYAFQDEKYLYMVMDYMSGGDLVNLMSNYEI-PEKWAKFYCAEVVLALDAIHTMGFVHRDVKPDNMLLDGEGHLKLADFGTCMRMDR-DGMVRSDTAVGTPDYISPEVLKSQGGEGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTY 278
BLAST of Rho-associated protein kinase vs. Ensembl Nematostella
Match: EDO42700 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0M7]) HSP 1 Score: 239.195 bits (609), Expect = 6.756e-69 Identity = 130/365 (35.62%), Postives = 207/365 (56.71%), Query Frame = 3 Query: 192 NFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKM-----------------------DPVTKYVNC-----NR------AIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFD-FGEDDVDTN 1181 + Q + + +L R+ DF+ LK+IG+GAFG+V+LV+ + TG ++A+KIL K+ ++ E + ERDI+ + +++W+VK++Y+FQD L++VM++LPGG+L+ + K + E++ FY AE +LAI+ +H GF+HRDIKPDN+L+D +GHIKLADFG C + DP+ NR +GTPDYI+PEV + Q Y K D+W+LGV++YE+ G PPF S++ TY K+M ++L FPP+ +S A D + + + + DI++ FF W+ ++D + +++ DTS FD F E D+DT+ Sbjct: 72 KLHAQKETEFLRLKRSRIGKEDFDSLKVIGRGAFGEVRLVQKQDTGHVYAMKILRKADMLEKEQVAHARAERDILAEAENQWVVKMYYSFQDDYYLFLVMEFLPGGDLMTLLMKKDTFTEEETRFYIAEALLAIDSIHQLGFIHRDIKPDNLLLDSRGHIKLADFGLCTGLKKAHRTEFYRDISPADIKDFSNGDPLDSKRRAATWKRNRRQLAYSTVGTPDYIAPEVFIQQG----YTKSCDFWSLGVIMYEMLIGYPPFCSESPQETYKKVMNWRETLVFPPEMPISPNARDLISR---------QRLSNIEDIRAQPFFKYVD----WENLRDRPAALPIQVKSIDDTSNFDEFPETDLDTS 419
BLAST of Rho-associated protein kinase vs. Ensembl Nematostella
Match: EDO36034 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJR1]) HSP 1 Score: 235.343 bits (599), Expect = 5.286e-68 Identity = 144/390 (36.92%), Postives = 203/390 (52.05%), Query Frame = 3 Query: 201 KQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCV------------------------------------------------KMDPV-----TKYVNC--NRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQG 1205 KQ + Y +L +M S F ++ IG GAFG+V LVR T L+A+KIL KS+V + ERDI+ + D+ W+VKL+Y+FQD + LY VMDY+PGG+L++ + K + E FY AE+VLAI+ +H GFVHRDIKPDNILID GHIKL DFG C +M P+ K++ C + +GTP+YI+PEVLL Y + DWW++GV+LYE+ G+PPF + T KI+ E L P +S A D + +L + +RLG + AS+IK+H FF + +W + + +P+ PV+ DT+ F D VD L S+ G Sbjct: 19 KQKETNYIRLKRTKMDISMFEKIRTIGIGAFGEVWLVRKTDTSMLYAMKILRKSEVFRRNQAAHVKAERDILAEADNEWVVKLYYSFQDQENLYFVMDYVPGGDLMSLLIKFGIFPEDYAKFYIAELVLAIDSVHRMGFVHRDIKPDNILIDKDGHIKLTDFGLCTGFRWTHDSKYYEKGQHMRQDSMEPDERAWEEMRATCHCGDISIDKPYSEMKPLERRHFRKHMRCQAHSLVGTPNYIAPEVLL----RIGYRQSCDWWSVGVILYEMLVGQPPFLAPTPAETQLKIINWETELRIPHQARLSREAKDLILRLCTNADMRLG-SNGASEIKAHPFF--ACVDWAY-LAKRVQAPYTPVIRFPTDTANF----DPVDPERLRTSDSG 396
BLAST of Rho-associated protein kinase vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2]) HSP 1 Score: 204.527 bits (519), Expect = 1.612e-57 Identity = 123/346 (35.55%), Postives = 185/346 (53.47%), Query Frame = 3 Query: 240 RMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMK-IDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLIC-DRSVRLGQTK-DASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFD--FGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYI 1262 + K SDF LK+IG+G+FG+V L ++KQ +A+K+LNKS + ER+++++ + ++V LHY+FQ +LY V+DY+ GG L + + E FYAAEI AI LH ++RD+KP+NIL+D KGHI L DFG C + + + + GTP+Y++PEVL Q Y K VDWW LG +LYE+ YG PPFYS + Y I+ L +S A ++ L+ D++ RLG + D DI++H FF S W + P+ P + LD +FD F + V + ++ S + + F GF+Y+ Sbjct: 68 KAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLC--KEGIDRSGTTSTFCGTPEYLAPEVLRKQD----YDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLR----TNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFR--SINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVREPVPGSVGKSADSNFVSASVDDPDDAFVGFTYV 401
BLAST of Rho-associated protein kinase vs. Ensembl Medaka
Match: rock1 (Rho associated coiled-coil containing protein kinase 1 [Source:NCBI gene;Acc:101158388]) HSP 1 Score: 389.423 bits (999), Expect = 1.488e-113 Identity = 184/415 (44.34%), Postives = 270/415 (65.06%), Query Frame = 3 Query: 39 LNNYVLLENNFQNV---VSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKST-----TFIGENIQFSGFSY 1259 +++ + +E F+ + + D K I+ D L D L D L NK NF ++K+ K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L +AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + + DR VRLG+ +IK H FF N +WTW+ I+D+ +P +P L +D DTS FD E+D +G + T F+G + F GF+Y Sbjct: 1 MSSEINMEGRFEKIDAMLKDPKSEINTDCLLDGLDALVYDL-DFPALRKNKSIDNFLNRYKETISKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSSWVVQLFFAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNK-DGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMNHKNALTFPDDSDISNDAKNLICAFLTDREVRLGRN-GVDEIKRHPFFKND--QWTWENIRDTAAPVVPELSSDTDTSNFDDIEED----------RGEEETFPIPKAFVGNQLPFVGFTY 399
BLAST of Rho-associated protein kinase vs. Ensembl Medaka
Match: rock1 (Rho associated coiled-coil containing protein kinase 1 [Source:NCBI gene;Acc:101158388]) HSP 1 Score: 382.104 bits (980), Expect = 3.717e-111 Identity = 176/380 (46.32%), Postives = 257/380 (67.63%), Query Frame = 3 Query: 39 LNNYVLLENNFQNV---VSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDD 1169 +++ + +E F+ + + D K I+ D L D L D L NK NF ++K+ K+ D RMK D+ ++K+IG+GAFG+VQLVRHK T ++A+K+L+K +++ + F+ EERDIM +S W+V+L +AFQD + LYMVM+Y+PGG+LVN MS +V EK FY AE+VLA++G+H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KM+ V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV L+E+ G+ PFY+D+L+ TY KIM H+ +L+FP D ++S A + + + DR VRLG+ +IK H FF N +WTW+ I+D+ +P +P L +D DTS FD E+D Sbjct: 1 MSSEINMEGRFEKIDAMLKDPKSEINTDCLLDGLDALVYDL-DFPALRKNKSIDNFLNRYKETISKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSSWVVQLFFAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKAGHLKLADFGTCMKMNK-DGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMNHKNALTFPDDSDISNDAKNLICAFLTDREVRLGRN-GVDEIKRHPFFKND--QWTWENIRDTAAPVVPELSSDTDTSNFDDIEED 374
BLAST of Rho-associated protein kinase vs. Ensembl Medaka
Match: rock2a (rho-associated protein kinase 2 [Source:NCBI gene;Acc:101172697]) HSP 1 Score: 375.941 bits (964), Expect = 8.548e-109 Identity = 180/402 (44.78%), Postives = 265/402 (65.92%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 ++++ D + ++L+ L DS L LD L NK F +++KV E+L D +MK DF +K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EER IM +S W+V+L AFQD LYMVM+Y+PGG+LVN S +V EK FY AE+V+A++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV ++E+ G+ PFY+D+L+ TY KIM H+ SL FP + E+S A + + + DR VRLG+ +IK H FF N +WT+D I+++ +P +P L +D+DTS FD ED DV+T ++ F+G + F GF+Y + Sbjct: 22 LEDMLRDPRSALNLESLLDSLNALVLDL-DYPALRKNKNIETFLNRYEKVVEELRDLQMKSEDFEKVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERGIMAFANSPWVVQLCCAFQDEHYLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVMALDAIHSMGFIHRDVKPDNMLLDRLGHLKLADFGTCMKMD-ATGMVRCDTAVGTPDYISPEVLKSQGGDGCYGRECDWWSVGVFIFEMLVGDTPFYADSLVGTYSKIMDHKNSLHFPEEVEISADAKNIICAFLTDREVRLGRN-GVEEIKQHPFFKND--QWTFDNIRETVAPVVPELSSDIDTSNFDEIEDDKGDVETVPTPKA--------FVGNQLPFVGFTYFK 409 HSP 2 Score: 53.9138 bits (128), Expect = 1.320e-6 Identity = 28/76 (36.84%), Postives = 43/76 (56.58%), Query Frame = 3 Query: 2940 LEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDV---QTCHFRLL-LSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 L + V+N KK WE+++V + + + FY + Q+ + +L + L VR V+ DV A + EIPRIFQI Y Sbjct: 1150 LSLPVRNNTKKFGWERKYVVVSSKKILFYNSEQDREQSIPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILY 1225
BLAST of Rho-associated protein kinase vs. Ensembl Medaka
Match: rock2a (rho-associated protein kinase 2 [Source:NCBI gene;Acc:101172697]) HSP 1 Score: 375.941 bits (964), Expect = 1.340e-108 Identity = 180/402 (44.78%), Postives = 265/402 (65.92%), Query Frame = 3 Query: 69 FQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 ++++ D + ++L+ L DS L LD L NK F +++KV E+L D +MK DF +K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EER IM +S W+V+L AFQD LYMVM+Y+PGG+LVN S +V EK FY AE+V+A++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV ++E+ G+ PFY+D+L+ TY KIM H+ SL FP + E+S A + + + DR VRLG+ +IK H FF N +WT+D I+++ +P +P L +D+DTS FD ED DV+T ++ F+G + F GF+Y + Sbjct: 22 LEDMLRDPRSALNLESLLDSLNALVLDL-DYPALRKNKNIETFLNRYEKVVEELRDLQMKSEDFEKVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERGIMAFANSPWVVQLCCAFQDEHYLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVMALDAIHSMGFIHRDVKPDNMLLDRLGHLKLADFGTCMKMD-ATGMVRCDTAVGTPDYISPEVLKSQGGDGCYGRECDWWSVGVFIFEMLVGDTPFYADSLVGTYSKIMDHKNSLHFPEEVEISADAKNIICAFLTDREVRLGRN-GVEEIKQHPFFKND--QWTFDNIRETVAPVVPELSSDIDTSNFDEIEDDKGDVETVPTPKA--------FVGNQLPFVGFTYFK 409 HSP 2 Score: 53.9138 bits (128), Expect = 1.477e-6 Identity = 28/76 (36.84%), Postives = 43/76 (56.58%), Query Frame = 3 Query: 2940 LEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDV---QTCHFRLL-LSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 L + V+N KK WE+++V + + + FY + Q+ + +L + L VR V+ DV A + EIPRIFQI Y Sbjct: 1150 LSLPVRNNTKKFGWERKYVVVSSKKILFYNSEQDREQSIPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILY 1225
BLAST of Rho-associated protein kinase vs. Ensembl Medaka
Match: rock2a (rho-associated protein kinase 2 [Source:NCBI gene;Acc:101172697]) HSP 1 Score: 369.777 bits (948), Expect = 8.930e-107 Identity = 178/386 (46.11%), Postives = 255/386 (66.06%), Query Frame = 3 Query: 117 LFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGED---DVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIR 1265 L DS L LD L NK F +++KV E+L D +MK DF +K+IG+GAFG+VQLVRHK + ++A+K+L+K +++ + F+ EER IM +S W+V+L AFQD LYMVM+Y+PGG+LVN S +V EK FY AE+V+A++ +H+ GF+HRD+KPDN+L+D GH+KLADFG+C+KMD T V C+ A+GTPDYISPEVL SQ + YG+E DWW++GV ++E+ G+ PFY+D+L+ TY KIM H+ SL FP + E+S A + + + DR VRLG+ +IK H FF N +WT+D I+++ +P +P L +D+DTS FD ED DV+T ++ F+G + F GF+Y + Sbjct: 9 LMDSLNALVLDL-DYPALRKNKNIETFLNRYEKVVEELRDLQMKSEDFEKVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERGIMAFANSPWVVQLCCAFQDEHYLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVMALDAIHSMGFIHRDVKPDNMLLDRLGHLKLADFGTCMKMD-ATGMVRCDTAVGTPDYISPEVLKSQGGDGCYGRECDWWSVGVFIFEMLVGDTPFYADSLVGTYSKIMDHKNSLHFPEEVEISADAKNIICAFLTDREVRLGRN-GVEEIKQHPFFKND--QWTFDNIRETVAPVVPELSSDIDTSNFDEIEDDKGDVETVPTPKA--------FVGNQLPFVGFTYFK 380 HSP 2 Score: 53.9138 bits (128), Expect = 1.419e-6 Identity = 28/76 (36.84%), Postives = 43/76 (56.58%), Query Frame = 3 Query: 2940 LEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDV---QTCHFRLL-LSSLIFVRSVSNVDVIHAKSSEIPRIFQICY 3155 L + V+N KK WE+++V + + + FY + Q+ + +L + L VR V+ DV A + EIPRIFQI Y Sbjct: 1121 LSLPVRNNTKKFGWERKYVVVSSKKILFYNSEQDREQSIPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILY 1196
BLAST of Rho-associated protein kinase vs. Planmine SMEST
Match: SMESG000041847.1 (SMESG000041847.1) HSP 1 Score: 2408.64 bits (6241), Expect = 0.000e+0 Identity = 1264/1268 (99.68%), Postives = 1268/1268 (100.00%), Query Frame = 3 Query: 30 MDKLNNYVLLENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIINEDKLQSTNRENEXXXXXXXXXXXXXXXXENQLHVVSTNFRKEEIISKKLQIDFSDLLTQHSCCQKTIEELETIREKLNSDLVIXXXXXXXXXXXXXXXXXXVNGYLKATNLKLMEVQTKFHESKLRCVQLESDYNNLIESHNLLEKDLVRLRNFISSKKDEESSINDSDFIQLKSEYESKDYDLQKSLLENKCIAKSLESLQNEKEKLSYSLIELEAKFTEQLHENRRQETELKEKEDLIKEMKDELSRLKVSIDESLKKEQNTHVKYSNLMKLHTQEKNKFEQELEEQRNKLSKIITDKTSEIKLINSSVETMKNSNTKLLKDLEMAKVKQESLVEKIKDIIHGQSTTAKEMMISEDLKSGFLGKRSGRIYHQLAKENKRLENLLDEFKKTSQCKEKELMKQVETITREKCQLELELSSSQDGYYENLNSHDISCNRAXXXXXXXXXXXFDSGFPHDSSLVSQSNFRRSIKNPFSKPPLLSHKASHLKQDLTNDVFPESGDENNGVKLRQKKSTNLQNRNSKTESMTMDFRNINQILEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDVQTCHFRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICYDKNDSLYLTAQMNPISKSTTSINSAESLXXXXXXXXXXXXXXXXXXXDFRKTSLARFLPIKGFKXXXXXXXXXXXXXXXXXFPVFLKGHIFTIITTETRSSCLICNKTFNINSGVGLSSSSTMTNAQKSLTNSFSIDSQTPMTCVTQHPDKIYQCRHCLLRIHGYDLDSILFNCTKSVVIQLCRAPSEIAQVNWVKYLNQFIKTQSKSICDSGMSTPNTKPRSSKN 3833 MDKLNNYVLLENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIINEDKLQSTN+ENEISKDILDKLMIDKKDLENQLHVVSTNFRKEEIISKKLQIDFSDLLTQHSCCQKTIEELETIREKLNSDLVIQQSSSEQEKELLTKELTEVNGYLKATNLKLMEVQTKFHESKLRCVQLESDYNNLIESHNLLEKDLVRLRNFISSKKDEESSINDSDFIQLKSEYESKDYDLQKSLLENKCIAKSLESLQNEKEKLSYSLIELEAKFTEQLHENRRQETELKEKEDLIKEMKDELSRLKVSIDESLKKEQNTHVKYSNLMKLHTQEKNKFEQELEEQRNKLSKIITDKTSEIKLINSSVETMK+SNTKLLKDLEMAKVKQESLVEKIKDIIHGQSTTAKEMMISEDLKSGFLGKRSGRIYHQLAKENKRLENLLDEFKKTSQCKEKELMKQVETITREKCQLELELSSSQDGYYENLNSHDISCNRASVSTIASSHSSFDSGFPHDSSLVSQSNFRRSIKNPFSKPPLLSHKASHLKQDLTNDVFPESGDENNGVKLRQKKSTNLQNRNSKTESMTMDFRNINQILEVNVKNKGKKMSWEKRFVRLEEQNLCFYGED+QTCHFRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICYDKNDSLYLTAQMNPISKSTTSINSAESLKSSNSSNENEVNVTVTEKKDFRKTSLARFLPIKGFKSNKNKENPELPNNLSNNFPVFLKGHIFTIITTETRSSC+ICNKTFNINSGVGLSSSSTMTNAQKSLTNSFSIDSQTPMTCVTQHPDKIYQCRHCLLRIHGYDLDSILFNCTKSVVIQLCRAPSEIAQVNWVKYLNQFIKTQSKSICDSGMSTPNTKPRSSKN Sbjct: 1 MDKLNNYVLLENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTNKENKKSDNVLNSNIINEDKLQSTNKENEISKDILDKLMIDKKDLENQLHVVSTNFRKEEIISKKLQIDFSDLLTQHSCCQKTIEELETIREKLNSDLVIQQSSSEQEKELLTKELTEVNGYLKATNLKLMEVQTKFHESKLRCVQLESDYNNLIESHNLLEKDLVRLRNFISSKKDEESSINDSDFIQLKSEYESKDYDLQKSLLENKCIAKSLESLQNEKEKLSYSLIELEAKFTEQLHENRRQETELKEKEDLIKEMKDELSRLKVSIDESLKKEQNTHVKYSNLMKLHTQEKNKFEQELEEQRNKLSKIITDKTSEIKLINSSVETMKDSNTKLLKDLEMAKVKQESLVEKIKDIIHGQSTTAKEMMISEDLKSGFLGKRSGRIYHQLAKENKRLENLLDEFKKTSQCKEKELMKQVETITREKCQLELELSSSQDGYYENLNSHDISCNRASVSTIASSHSSFDSGFPHDSSLVSQSNFRRSIKNPFSKPPLLSHKASHLKQDLTNDVFPESGDENNGVKLRQKKSTNLQNRNSKTESMTMDFRNINQILEVNVKNKGKKMSWEKRFVRLEEQNLCFYGEDLQTCHFRLLLSSLIFVRSVSNVDVIHAKSSEIPRIFQICYDKNDSLYLTAQMNPISKSTTSINSAESLKSSNSSNENEVNVTVTEKKDFRKTSLARFLPIKGFKSNKNKENPELPNNLSNNFPVFLKGHIFTIITTETRSSCVICNKTFNINSGVGLSSSSTMTNAQKSLTNSFSIDSQTPMTCVTQHPDKIYQCRHCLLRIHGYDLDSILFNCTKSVVIQLCRAPSEIAQVNWVKYLNQFIKTQSKSICDSGMSTPNTKPRSSKN 1268
BLAST of Rho-associated protein kinase vs. Planmine SMEST
Match: SMESG000049701.1 (SMESG000049701.1) HSP 1 Score: 309.686 bits (792), Expect = 7.395e-86 Identity = 168/409 (41.08%), Postives = 255/409 (62.35%), Query Frame = 3 Query: 66 NFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTN---FYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIM---MKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVC-FYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPD-DEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLK-STTFIGENIQFSGFSYIR 1265 N+++ V D +++L+ L DS + +C+ LP +K N F K K +K+ R++ SDF+ +++IG+GAFG+V +VR K+ G+++A+K L+K ++ +QEERD++ MKI S WI +LHYAFQD LY VMD+ GG+++ +SK L +++ FY AE+V++I+ +H G++HRDIKPDN+L+D GHI LADFGSCVK+ P + RA+GTPDYISPE+L S + YG E DWW+LG++++E+ YGE PFY+++ TY +IM E P + D+VS A D +K+LIC + RLG K D K+H FF RE WD ++ +PFIP + + DTS F+F DD + N ++G S+ F G ++ GF++ + Sbjct: 21 NYKSSVPD---SVTLEFLIDSLFCTYYECR----LPFHKDEKNVAQFIKSIKGTVDKIESLRIRRSDFDTIRVIGRGAFGKVSVVRFKEKGEIYAMKSLHKYDILKKIDAACFQEERDVLFQAMKIKSPWITRLHYAFQDEFYLYFVMDFYNGGDMLTLLSKFNDRLPEEITKFYIAEVVMSIDVVHKLGYLHRDIKPDNLLLDSLGHIVLADFGSCVKLRPNGTTIT-ERAVGTPDYISPEILRSAEGHGPYGVECDWWSLGIVIHEMLYGELPFYNEDFSETYWQIMNFETCFQIPTEYDDVSDEAEDLIKQLICKKECRLG-NKGIDDFKNHPFF----REIDWDNLRSYNAPFIPEVSSAEDTSNFEF--DDFNAN-----HEGPPLSSNFKGCHLPCIGFTFTK 409
BLAST of Rho-associated protein kinase vs. Planmine SMEST
Match: SMESG000049701.1 (SMESG000049701.1) HSP 1 Score: 309.686 bits (792), Expect = 7.754e-86 Identity = 168/409 (41.08%), Postives = 255/409 (62.35%), Query Frame = 3 Query: 66 NFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNKYFTN---FYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIM---MKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVC-FYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPD-DEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLK-STTFIGENIQFSGFSYIR 1265 N+++ V D +++L+ L DS + +C+ LP +K N F K K +K+ R++ SDF+ +++IG+GAFG+V +VR K+ G+++A+K L+K ++ +QEERD++ MKI S WI +LHYAFQD LY VMD+ GG+++ +SK L +++ FY AE+V++I+ +H G++HRDIKPDN+L+D GHI LADFGSCVK+ P + RA+GTPDYISPE+L S + YG E DWW+LG++++E+ YGE PFY+++ TY +IM E P + D+VS A D +K+LIC + RLG K D K+H FF RE WD ++ +PFIP + + DTS F+F DD + N ++G S+ F G ++ GF++ + Sbjct: 21 NYKSSVPD---SVTLEFLIDSLFCTYYECR----LPFHKDEKNVAQFIKSIKGTVDKIESLRIRRSDFDTIRVIGRGAFGKVSVVRFKEKGEIYAMKSLHKYDILKKIDAACFQEERDVLFQAMKIKSPWITRLHYAFQDEFYLYFVMDFYNGGDMLTLLSKFNDRLPEEITKFYIAEVVMSIDVVHKLGYLHRDIKPDNLLLDSLGHIVLADFGSCVKLRPNGTTIT-ERAVGTPDYISPEILRSAEGHGPYGVECDWWSLGIVIHEMLYGELPFYNEDFSETYWQIMNFETCFQIPTEYDDVSDEAEDLIKQLICKKECRLG-NKGIDDFKNHPFF----REIDWDNLRSYNAPFIPEVSSAEDTSNFEF--DDFNAN-----HEGPPLSSNFKGCHLPCIGFTFTK 409
BLAST of Rho-associated protein kinase vs. Planmine SMEST
Match: SMESG000057753.1 (SMESG000057753.1) HSP 1 Score: 305.449 bits (781), Expect = 1.763e-85 Identity = 152/366 (41.53%), Postives = 226/366 (61.75%), Query Frame = 3 Query: 186 FTNFYKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDPVTKYVNCNRAIGTPDYISPEVLLSQS-DNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDLDTSYFDFGEDDVDTNFLNQSNQGLKSTTFIGENIQFSGFSYIRWQNTN 1280 F+NF EK+ R+ SDF ++K +GQG FG+V LVRHK T +++A+KI++KS V FW EERDIM K S W++K Y F D K+LY+VM+Y+PGG+L +WM+++E ++ FYA E+VLA+ LHN GF+HRD+KPDN+L+D GH+KLADFG+C++ V N +GTPDYI PE+L + + + G E DWWA G+++YE+FYGE PF ++ Y IM ++ +L +P D +DFM K++ + + R+ D + IKSH + NS +W + I++ SP I + + DT+Y + +D N SN + + F GEN+ FSGF++ R+ N Sbjct: 59 FSNFS-------EKIYKLRVSLSDFAVIKTVGQGGFGRVDLVRHKSTKNVYAMKIMDKSTFVNNSFNGFW-EERDIMAKNSSDWLIKCFYTFMDLKKLYIVMEYMPGGDLYHWMTELEDFSDEQTHFYAMELVLAVEVLHNMGFIHRDLKPDNMLLDKNGHMKLADFGTCIRTK--NGKVKTNFQVGTPDYICPEILRNTGIHDLEVGFETDWWAFGIVIYELFYGETPFEGESTSTLYQNIMRYKSTLIYPDDKPAKPEFIDFMSKILTEPTERM----DITGIKSHPYLTNSGYKWNFSDIREHQSPVIFEVSGEDDTNYITYDPND---RRNNISNNFINNNYFSGENLAFSGFTFNRFNTYN 407
BLAST of Rho-associated protein kinase vs. Planmine SMEST
Match: SMESG000068357.1 (SMESG000068357.1) HSP 1 Score: 245.358 bits (625), Expect = 6.429e-70 Identity = 138/390 (35.38%), Postives = 216/390 (55.38%), Query Frame = 3 Query: 198 YKQHKKVYEKLVDFRMKYSDFNLLKIIGQGAFGQVQLVRHKQTGDLFALKILNKSQVVTCEGTLFWQEERDIMMKIDSRWIVKLHYAFQDPKRLYMVMDYLPGGNLVNWMSKVEVLLEKDVCFYAAEIVLAINGLHNFGFVHRDIKPDNILIDIKGHIKLADFGSCVKMDP---------VTKYVNCNRA------------------------IGTPDYISPEVLLSQSDNTKYGKEVDWWALGVMLYEIFYGEPPFYSDNLINTYGKIMTHEQSLSFPPDDEVSGMALDFMKKLICDRSVRLGQTKDASDIKSHIFFNNSSREWTWDTIQDSTSPFIPVLENDL-DTSYF-DFGEDDVDTN---FLNQSNQGLKSTTFIGENIQFSGF 1253 + Q + Y +L R+ DF L++IG+GAFG+V+LV+ K G ++A+KIL K ++ + + ERDI+ K D+ W+VK+ ++FQD LY+VM++LPGG+++ + K++ L E+ FY AE LAI+ +H+ GF+HRDIKPDN+L+D KGHIKL+DFG C + +++ C+ A +GTPDYI+PEV + Y DWW+LGV+++E+ G PPF SD TY K+M L FPPD +S ++ + + + + + + RLG +IK+ FF+ W+ I++ + IPV+ N + DTS F DF + D+ N ++ N+ K FI N + F Sbjct: 78 HAQKESEYLRLKRARLVVDDFAALRVIGKGAFGEVRLVQKKDNGRIYAMKILRKVDMLQKDQIAHVRAERDILAKADNPWVVKMFFSFQDSTNLYLVMEFLPGGDMMTLLMKLDTLSEEQSQFYVAETALAIDSIHSMGFIHRDIKPDNLLLDAKGHIKLSDFGLCTGLKKSHRTEFYKDLSQAKPCDFAQSPLDSKRRAESWRKNRRNLAYSTVGTPDYIAPEVFQQKG----YTSSCDWWSLGVIMFEMLIGYPPFCSDTPGETYKKVMAFRDHLVFPPDTPISDVSKEVITEFLEEGNKRLGFNSGIVEIKNKSFFHGVD----WEHIRERPAA-IPVIVNSIDDTSNFDDFPDADLSWNINHIQDRENRYKKELAFI--NYTYKAF 456 The following BLAST results are available for this feature:
BLAST of Rho-associated protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Rho-associated protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Rho-associated protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Rho-associated protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30031032 ID=SMED30031032|Name=Rho-associated protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=4011bpback to top protein sequence of SMED30031032-orf-1 >SMED30031032-orf-1 ID=SMED30031032-orf-1|Name=SMED30031032-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1269bp MDKLNNYVLLENNFQNVVSDDKENISLDLLFDSFQNLFLDCKSVSNLPTNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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