A disintegrin and metalloproteinase with thrombospondin motifs 2

Overview


Name	A disintegrin and metalloproteinase with thrombospondin motifs 2
Smed ID	SMED30031005
Length (bp)	1366

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of A disintegrin and metalloproteinase with thrombospondin motifs 2 (SMED30031005) t-SNE clustered cells

Violin plots show distribution of expression levels for A disintegrin and metalloproteinase with thrombospondin motifs 2 (SMED30031005) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of A disintegrin and metalloproteinase with thrombospondin motifs 2 (SMED30031005) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30031005

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30031005	h1SMcG0009868	SmedASXL_016093	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30031005	h1SMcG0009868	SmedASXL_010137	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30031005	h1SMcG0009868	dd_Smed_v4_16551_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30031005	h1SMcG0009868	dd_Smed_v4_16551_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30031005	h1SMcG0009868	dd_Smed_v4_16551_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30031005	h1SMcG0009868	dd_Smed_v4_16551_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
anterior side	SMED30031005	h1SMcG0009868	dd_Smed_v4_16551_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30031005	h1SMcG0009868	dd_Smed_v4_10305_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30031005	h1SMcG0009868	dd_Smed_v4_10305_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30031005	h1SMcG0009868	dd_Smed_v4_10305_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30031005	h1SMcG0009868	dd_Smed_v6_16551_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30031005	h1SMcG0009868	dd_Smed_v6_10305_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Human
Match: LEXM (lymphocyte expansion molecule [Source:HGNC Symbol;Acc:HGNC:26854])

HSP 1 Score: 79.337 bits (194), Expect = 2.261e-15
Identity = 71/291 (24.40%), Postives = 133/291 (45.70%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF--------YSKSVPPNVGPGSYNVKHQEKSSKNRFSSEM---WKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY-NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITN 921
            + FG    +F    ++P  +  ++F        YS  V  ++GPG+Y+ K +   SK +   E+   W       +   +P+F  +   + +  K+++LGPG Y +++ +++L +   +T+ L S G  RF     + YPGP  YG    P   +++    R ++    L+ R  N           +GPG Y  +S +   +    G RG YD  + DRS+P+  GH+++          + +F  E++  H+K H   G F +  + P+ P +R++W +    P  +  
Sbjct:   27 APFGVQSHRFDISAVYPNWKKFSTFTEAPYSTRYSTQVS-HIGPGTYSSK-ETCFSKKKLMKEVDTGWAKAQEATRLTQLPHFQYQAIMKEKRLKEQKLGPGSYNLKDFLEQLREKPCSTRGLLSSGEVRFRGLTGNYYPGPGNYGEKGNPYTKLEENAWNRSHSEG--LMCRMSNKPHPRPHQGSGLGPGTYFFKSDLETYVARSVGTRGPYDTFSGDRSKPLPYGHYSMQKKKPRELMNFKSFVEELNSHHNKKH---GVFSKLPRNPKTPTERIYWANLSQCPRTLAT 310

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Human
Match: LEXM (lymphocyte expansion molecule [Source:HGNC Symbol;Acc:HGNC:26854])

HSP 1 Score: 78.9518 bits (193), Expect = 3.113e-15
Identity = 71/291 (24.40%), Postives = 133/291 (45.70%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF--------YSKSVPPNVGPGSYNVKHQEKSSKNRFSSEM---WKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY-NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITN 921
            + FG    +F    ++P  +  ++F        YS  V  ++GPG+Y+ K +   SK +   E+   W       +   +P+F  +   + +  K+++LGPG Y +++ +++L +   +T+ L S G  RF     + YPGP  YG    P   +++    R ++    L+ R  N           +GPG Y  +S +   +    G RG YD  + DRS+P+  GH+++          + +F  E++  H+K H   G F +  + P+ P +R++W +    P  +  
Sbjct:   27 APFGVQSHRFDISAVYPNWKKFSTFTEAPYSTRYSTQVS-HIGPGTYSSK-ETCFSKKKLMKEVDTGWAKAQEATRLTQLPHFQYQAIMKEKRLKEQKLGPGSYNLKDFLEQLREKPCSTRGLLSSGEVRFRGLTGNYYPGPGNYGEKGNPYTKLEENAWNRSHSEG--LMCRMSNKPHPRPHQGSGLGPGTYFFKSDLETYVARSVGTRGPYDTFSGDRSKPLPYGHYSMQKKKPRELMNFKSFVEELNSHHNKKH---GVFSKLPRNPKTPTERIYWANLSQCPRTLAT 310

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Xenopus
Match: ENSXETT00000045218.1 (lymphocyte expansion molecule [Source:NCBI gene;Acc:100491026])

HSP 1 Score: 127.487 bits (319), Expect = 5.284e-32
Identity = 113/388 (29.12%), Postives = 176/388 (45.36%), Query Frame = 1

Query:   88 MSKSAFGSSVPKFTCYGIHPKLQSTNSF--------YSKSVPPNVGPGSYNVKHQEKSS---KNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATK-ILQSKGRRFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRG-GNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY---NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSK-ISDPKTIDVLRSRVR 1191
             S + FGS   +F    +HP  + T S+         +  +   +GPG+YN +  + S    +   S+  WK     EK  T+P+ + KE  +     K+ LGPG Y ++  +  L K     + +  +K  RF  + + C PGP +YG    P  ++++     K A+S  ++D   G  + LP+     +GPG YN++S IN+ L H  G RG YD  +  R QPI  GH A   +    PG Y   +F  +++  H K +   G F    QYP+ P +R+F     N P  + N   P  Y+          S A F SS  R  K +     G NN  +G GRY+      G++     S+F S   + +S+P    +L  R+R
Sbjct:    6 FSGAPFGSQSARFDVSAVHPDSKKTGSYTQVPYCRRATSELERRLGPGTYNAEQSDFSPSVLEKNASAPAWKRAQETEKLTTMPHLLYKETYERNRLLKQNLGPGRYNIKSFLDLLEKKPSCIRGVCSTKEERFKKNEQFCTPGPGSYGKGGNPYSLLEERV--SKSASSKGIMDTSPGEGHSLPST-GCELGPGTYNLKSSINETLAHVVGNRGPYDLFSASREQPILYGHFAEPKNRGPEPGAYKVKSFTEDLESHHRKKY---GVFGNLAQYPKVPTERIFI----NRPKTMGNP-GPGLYDPKPFYEPKRHSAAPFLSSAKRFEKKSCRLLFGSNNP-VGVGRYDVAKHLRGKAATPLRSSFLSKTERYLSNPARDKILEERLR 381

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Mouse
Match: Lexm (lymphocyte expansion molecule [Source:MGI Symbol;Acc:MGI:2681853])

HSP 1 Score: 87.0409 bits (214), Expect = 5.036e-18
Identity = 91/347 (26.22%), Postives = 159/347 (45.82%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF----YSK--SVP-PNVGPGSYNVKHQEKSSK--NRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFH----IGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY----NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRY 1074
            + FG    +F    ++P  +  ++F    YS+  SV   ++GPG+YN K    S K   +     W   +   +   +P+F  +  K+ + ++  + GPG Y +++ + +L K   + + L S G  RF   I + YPGP  YG    P   +++    R +++   L+ R  N      PP FH    +GPG Y I+S +   +   TG RG YD  + +RS P+  GH+++     + P +     +F +E++  H K      K+ R+   P+ P +R+FWT     P ++ +   P S+ L     +   ++  F  +  R    A    +G  N  +G GRY
Sbjct:   24 APFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDG--LMCRVSNK-----PPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSV---QKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRD---PKHPTERIFWTTLSQCPKNM-DIAGPGSW-LPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNP-VGVGRY 354

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Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF----YSK--SVP-PNVGPGSYNVKHQEKSSK--NRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFH----IGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY----NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRY 1074
            + FG    +F    ++P  +  ++F    YS+  SV   ++GPG+YN K    S K   +     W   +   +   +P+F  +  K+ + ++  + GPG Y +++ + +L K   + + L S G  RF   I + YPGP  YG    P   +++    R +++   L+ R  N      PP FH    +GPG Y I+S +   +   TG RG YD  + +RS P+  GH+++     + P +     +F +E++  H K      K+ R+   P+ P +R+FWT     P ++ +   P S+ L     +   ++  F  +  R    A    +G  N  +G GRY
Sbjct:   24 APFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDG--LMCRVSNK-----PPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSV---QKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRD---PKHPTERIFWTTLSQCPKNM-DIAGPGSW-LPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNP-VGVGRY 354

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Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF----YSK--SVP-PNVGPGSYNVKHQEKSSK--NRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFH----IGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY----NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRY 1074
            + FG    +F    ++P  +  ++F    YS+  SV   ++GPG+YN K    S K   +     W   +   +   +P+F  +  K+ + ++  + GPG Y +++ + +L K   + + L S G  RF   I + YPGP  YG    P   +++    R +++   L+ R  N      PP FH    +GPG Y I+S +   +   TG RG YD  + +RS P+  GH+++     + P +     +F +E++  H K      K+ R+   P+ P +R+FWT     P ++ +   P S+ L     +   ++  F  +  R    A    +G  N  +G GRY
Sbjct:   24 APFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDG--LMCRVSNK-----PPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSV---QKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRD---PKHPTERIFWTTLSQCPKNM-DIAGPGSW-LPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNP-VGVGRY 354

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. UniProt/SwissProt
Match: sp|B1H283|LEXM_RAT (Lymphocyte expansion molecule OS=Rattus norvegicus OX=10116 GN=Lexm PE=2 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 2.573e-17
Identity = 93/345 (26.96%), Postives = 153/345 (44.35%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF----YSK--SVP-PNVGPGSYNVKHQEKSSKNRFSSEM----WKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGIPQDIIDQADIRRKYANSVPLLDRGGNSNRLPT--PPSFH----IGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY-NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRY 1074
            + FG    +F    +HP  +  ++F    YS+  SV   ++GPG+YN K  E     +F  +     W       +   +P+F  +  K+   ++  + GPG Y +++ + +L K   + + L S G  RF   I + YPGP  YG   +   Q +      NS       G   RL +  PP  H    +GPG Y I+S I   +   TG RG YD  + +RS P+  GH+++          + +F +E++  H K    +G F +  + P+ P +R++WT     P D+ N   P S+ L     +   ++  F  +  R    A    +G  N  +G GRY
Sbjct:   11 APFGVQSHRFDVSAVHPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSK--ETCFSKKFLEQKLGAGWARAQEASRLTQLPHFHFQAIKKEREQQANKRGPGSYNIKDFLTELQKKPQSKRGLLSSGETRFRGLIGNYYPGPGNYGEKGNPYTQLE-----KNSWNRSHSDGLMCRLSSKPPPLSHQGSGLGPGTYTIKSDIETFVEKSTGTRGPYDIFSGERSSPVPYGHYSVQKKKPRELTSFKSFVDELNAPHKK---KQGGFSKYPRDPKHPTERIYWTTLSQCPKDV-NVAGPGSW-LPHETEQKHVNRPPFLLASKRSGLKACQMLLGTWNP-VGVGRY 342

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. UniProt/SwissProt
Match: sp|A2AVQ5|LEXM_MOUSE (Lymphocyte expansion molecule OS=Mus musculus OX=10090 GN=Lexm PE=2 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 3.522e-17
Identity = 91/347 (26.22%), Postives = 159/347 (45.82%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF----YSK--SVP-PNVGPGSYNVKHQEKSSK--NRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFH----IGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY----NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRY 1074
            + FG    +F    ++P  +  ++F    YS+  SV   ++GPG+YN K    S K   +     W   +   +   +P+F  +  K+ + ++  + GPG Y +++ + +L K   + + L S G  RF   I + YPGP  YG    P   +++    R +++   L+ R  N      PP FH    +GPG Y I+S +   +   TG RG YD  + +RS P+  GH+++     + P +     +F +E++  H K      K+ R+   P+ P +R+FWT     P ++ +   P S+ L     +   ++  F  +  R    A    +G  N  +G GRY
Sbjct:   24 APFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDG--LMCRVSNK-----PPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSV---QKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRD---PKHPTERIFWTTLSQCPKNM-DIAGPGSW-LPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNP-VGVGRY 354

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. UniProt/SwissProt
Match: sp|Q3ZCV2|LEXM_HUMAN (Lymphocyte expansion molecule OS=Homo sapiens OX=9606 GN=LEXM PE=2 SV=4)

HSP 1 Score: 78.9518 bits (193), Expect = 1.495e-14
Identity = 71/291 (24.40%), Postives = 133/291 (45.70%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSF--------YSKSVPPNVGPGSYNVKHQEKSSKNRFSSEM---WKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGR-RFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQY-NFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITN 921
            + FG    +F    ++P  +  ++F        YS  V  ++GPG+Y+ K +   SK +   E+   W       +   +P+F  +   + +  K+++LGPG Y +++ +++L +   +T+ L S G  RF     + YPGP  YG    P   +++    R ++    L+ R  N           +GPG Y  +S +   +    G RG YD  + DRS+P+  GH+++          + +F  E++  H+K H   G F +  + P+ P +R++W +    P  +  
Sbjct:   27 APFGVQSHRFDISAVYPNWKKFSTFTEAPYSTRYSTQVS-HIGPGTYSSK-ETCFSKKKLMKEVDTGWAKAQEATRLTQLPHFQYQAIMKEKRLKEQKLGPGSYNLKDFLEQLREKPCSTRGLLSSGEVRFRGLTGNYYPGPGNYGEKGNPYTKLEENAWNRSHSEG--LMCRMSNKPHPRPHQGSGLGPGTYFFKSDLETYVARSVGTRGPYDTFSGDRSKPLPYGHYSMQKKKPRELMNFKSFVEELNSHHNKKH---GVFSKLPRNPKTPTERIYWANLSQCPRTLAT 310

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. TrEMBL
Match: A0A1I8HJX0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031511g1 PE=4 SV=1)

HSP 1 Score: 194.126 bits (492), Expect = 3.064e-53
Identity = 140/407 (34.40%), Postives = 216/407 (53.07%), Query Frame = 1

Query:   91 SKSAFGSSVPKFTCYGIHPK--LQSTNSFYSKSVPPNVGPGSYNVKHQEKSSKNRFSSEM----WKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMK---KLSKDNHATKILQSKGRRFSDDI-KDCYPGPSTYG---IPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQ--RGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYK---IGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNC----DSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINLPEMKKKKETHLATE 1245
            S + FG    +F   GIHPK  L  T +     +  ++GPGSY+V    + S  R +S      WK  Y++ +Q  IP+ + KE+   + E+KR+LGPGYY+V  S     ++SK      +L+++  RF     ++  PGP +YG   +P    ++ D +R++   V +LD GG+  R P      +GPG Y I S  + +   + G+  RG Y+  +LDR QP+KTGH+A + + NLGPGQYNF + +   +       GKFL+  QYP KP  R++W  P   P D TN+VS ASY+ +   +K     KS+AGF S+  R +K +L  F  +N   +GPGRY+     D+  +    N F S  ++ +S         V R R+R  ++P  ++ +  H+ATE
Sbjct:   11 SGAPFGFQSTRFDVSGIHPKRKLPGTLTQVPGGISADLGPGSYDVLQYNEFSDKRVASRAQGPNWKRAYDVHRQSQIPHLLYKEQHAEKEEQKRKLGPGYYDVAGSQDYRLEVSKRG----LLEAREPRFRGHTGQEGNPGPGSYGKSGVPHLHKEEMDEKRRHCGRVGMLDCGGS--RAPPQQGTDLGPGTYQIPSFTDLLAAKKAGKNSRGPYEVFSLDRDQPVKTGHYARMSTGNLGPGQYNFKDGVADLNRPEKRNHGKFLKMVQYPAKPCDRIYWMTPATVPPDPTNKVSAASYHPTDPNFKKESFSKSEAGFLSTSNRQDKRSLM-FFTKNFNQVGPGRYDIQRQEDTAHVNAHTNDFVSKTEARLSHGQQ----QVYRERLRDKDIPPGRRFRVDHVATE 406

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. TrEMBL
Match: A7SMX3 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g233391 PE=4 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 8.479e-39
Identity = 121/394 (30.71%), Postives = 201/394 (51.02%), Query Frame = 1

Query:   91 SKSAFGSSVPKFTCYGIHPKLQSTNSF----YSK----SVPPNVGPGSYNVKH---QEKSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATK-ILQSKGRRFSDDIKDCYPGPSTYG---IPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYN---FGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAG----FGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSK---ISDPKTIDVLRSR-VRP 1194
            S + FG    +F    IHPK ++  +F    Y K     V   +GPGSYN++     +KS   R S   W+  Y   +   IP+ + KE+ + +  +KR LGPG Y +++ M+ +++   +T+   +++  RF    +   PGP TYG   IP  ++++ +  RK  ++V +LD G +  R       H+ PG Y +ES  +++ +H   +RG YD    +R++PI  G+ A+ +  NLGPG+Y+   F +E    H + H   GKFL+  ++P+ P +R++       P D  ++  P SY    S   +GK +A     FGSS  RM++ A   F+G  N  +GPGRY+ D     +  +    AF S   +   I D   ++ +R++ VRP
Sbjct:    7 SGAPFGVQTSRFDVSSIHPKSKTPGTFTQVPYDKKCMTEVNRRLGPGSYNIEAGGFNKKSVLERASGPGWERAYETSRLAKIPHLLYKEQWEKKQYQKRMLGPGTYNIKDFMELMAEKPRSTRGECETRAARFESSTQSGVPGPGTYGKGGIPNAVLEEKE--RKSVSNVGMLDSGKSYRRQLPEVGSHLCPGQYEMESFTDEMASHVVSKRGPYDLFTGERNKPITVGYFAMPLRQNLGPGEYDLKSFLSENTGEHKQRH---GKFLKVTRFPDYPTERIYCCSLSQCPRD-PSEPGPGSY----SAKDLGKPEAAKRPPFGSSAGRMDRHARRFFLGSTNP-VGPGRYSVDRYENAQHIDGHTGAFNSKTRRYDLIRDKYMMERIRAKDVRP 389

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. TrEMBL
Match: A0A210Q094 (Uncharacterized protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT09195 PE=4 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 1.315e-34
Identity = 118/376 (31.38%), Postives = 184/376 (48.94%), Query Frame = 1

Query:  124 FTCYGIHPKLQSTNSF----YSKS----VPPNVGPGSYNVKH---QEKSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATK-ILQSKGRRFSDDIKDCYPGPSTYG---IPQDIIDQADIRRKYANSVPLLDRGGNSNR-LPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINL 1203
            F   G+HPK +   +F    Y K     +   +GPGSY V +     KS + R S   W   Y +E+   +P+ + K++ + +    R+LGPG Y++++ ++   +   + + I Q+   RF D   D  PGP TYG   +P   I Q +  +K A+++ +LD G ++ R LPT  S  +GPG YN +S   + +N  T  RG YD  + DR++PI  GH A     NLGPGQY+  + +D         +GKF + KQ P K  +R+F       P +  +   P SY   +      K+  GF S+  R +K +   F   N   +GPGRY+       +  N  +S FKS   K+ +      L+ RVRP ++
Sbjct:   27 FDVSGVHPKSKYPGTFTEIPYDKKSIDVLNRRLGPGSYKVDNGGFSSKSVEERASGPGWSRAYEVERMAALPHLLHKDQWELKKMLARKLGPGSYDIKDFLQNGDEKPRSYRGICQTLSYRFKDQSVDNTPGPGTYGDGGVPHAAIIQKE--KKSASTIGMLDAGSSTPRNLPTVGS-ELGPGTYNFKSFAEERVNKVTSLRGPYDLFSGDRNKPITVGHLAAPKLANLGPGQYDLQSFVDDLKTVHRKRQGKFGKVKQPPTKATERIFCHTLQQCPKE-ESFPGPGSYEPVELSKPGSKNAPGFLSTAQRNDKMS-QRFFTRNFNPVGPGRYDIQKWEEAQHRNGNDSVFKSRTGKL-NAAMEKFLKERVRPKDV 396

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. TrEMBL
Match: N1PB98 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_226751 PE=4 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 1.517e-32
Identity = 108/363 (29.75%), Postives = 177/363 (48.76%), Query Frame = 1

Query:  103 FGSSVPKFTCYGIHPKLQSTNSF----YSK----SVPPNVGPGSYNVK---HQEKSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHAT-KILQSKGRRFSDDIKDC--YPGPSTYG---IPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYN--LSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKS 1134
            FG    +F   GIHPK ++  +F    Y K    S+   +GPG Y++      +KS + R     W   Y +++   +P+ + K++ + +   K++LGPG Y +++ +++  +   +T  I+ +K  RF + +      PGP TYG   +P   +++    +K A+++ LL   G    LPT  S  +GPG Y  +S   ++    T  RG YD  + DR++PIKTGH A + + NLGPGQY   + +D +  +     G+F + +QYPEK   R++       P +   +  P  Y   ++  +    K   GF SS  R +K +   F G  N  +GPGRY        +  N   S FKS
Sbjct:   11 FGVQTARFDVSGIHPKNKTPGTFTQTPYCKKSNTSLSCQLGPGRYDIGLGGFSDKSVEERAGGPGWARAYEVQRLAALPHLLHKQQWELKRLLKKKLGPGSYNIKDFLEQSGEKPRSTLGIIHTKEERFKEKLTQAQETPGPGTYGEGGVPHAAVEEKA--KKSASTIGLLGASGAERSLPTVGS-GLGPGTYQFKSFTEKIDEKVTSLRGPYDLFSGDRNKPIKTGHLASVTNSNLGPGQYKIKSFVDDWSTEHKQRTGRFFKMEQYPEKAIDRIYSFSLPQNPRN-REEPGPGQYEPKMADQVISHAKKSPGFLSSSQRSDKLSTKFFTGNQNP-VGPGRYVIQKLEDAQHRNGHTSVFKS 368

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. TrEMBL
Match: A0A1S3JSZ9 (lymphocyte expansion molecule OS=Lingula unguis OX=7574 GN=LOC106175621 PE=4 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 2.807e-32
Identity = 114/386 (29.53%), Postives = 184/386 (47.67%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSFYS--------KSVPPNVGPGSYNVK---HQEKSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHAT-KILQSKGRRFSDDIKDCYPGPSTYGI---PQDIIDQADIRRKYANSVPLLDRGGNSNR-LPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINLP 1206
            + FG+   +F    +HPK +   +F          +S+    GPG Y V+      KS + R S   W  QY +++   +P+ + KE+ + +   KR+L PG Y +++ ++   +   +   I  +K  RF + + +  PGP TYGI   P   ++Q ++     ++V +LD   +  R LP   S  +GPG YN ES   Q+    T  RG YD  +  R++PI TGH A+   H LGPGQY+  + +D +        GK  + +Q+P+KP +R+  +     P ++     P +YN  +       +  GF SS  R ++ A   F   N   +G GRY+       +  N  ES FKS   KIS  K    L+ R+R  ++P
Sbjct:    9 APFGTQTARFDVSAVHPKNKMPGTFTQTPYCRVSMESLNRTRGPGKYAVEVGGFSPKSVEERASGPGWARQYEVQRMAAMPHLLHKEQWELKRLLKRKLAPGTYNIKDFLETSDERPRSIYGICATKEPRFRNTVTNATPGPGTYGIGGVPHAALEQKEM--ASTSTVGMLDAVSSMPRSLPLVGS-DLGPGSYNFESFTKQLERKVTSLRGPYDLFSGQRNKPITTGHLAVPTWHTLGPGQYDLKSFVDDWGTIHKKKHGKMGKVQQHPDKPSERILVSTLSQCPKEM-GAPGPGAYNAKEISKPQAHNSPGFLSSARRDDRMA-QKFFTRNFNPVGAGRYDVQKWEEAQHVNGHESVFKSKSGKISL-KREQFLKERLRAKDVP 388

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Cavefish
Match: ENSAMXT00000013749.2 (lymphocyte expansion molecule [Source:NCBI gene;Acc:103032211])

HSP 1 Score: 88.5817 bits (218), Expect = 9.815e-19
Identity = 101/387 (26.10%), Postives = 170/387 (43.93%), Query Frame = 1

Query:   97 SAFGSSVPKFTCYGIHPKLQSTNSFYSKS--------VPPNVGPGSYNVKHQEKSSKNRFSSEM---WKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATK-ILQSKGRRFSDDIKDCYPGPSTYGIPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIES-PINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYN-FGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQ---SLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISD-PKTIDVLRSRVRPINL 1203
            + FGS   +F   G+HP  +   ++   S        +  N+GPG+YN    + S++      M   WK      +   IP+ + ++    +   K ++GPG Y++    ++L K   + + I +++  RF  D ++   GP  Y I   I    D+ +K  +   + +      R     S   GPG Y     P   +   +   RG    N++D S  +K     I+   NLGPG+Y  FG E+ R   K H   G F   +QYP  P +R++ +     P  +T    P  Y++S    S     ++ A F SS  R +K ++   + +N+ ++GPGRY    K    +G+S  SAF S   +  + P      + R+RP N+
Sbjct:   11 APFGSQSHRFDVSGVHPANKRVGTYTQISCCKRRTSDLERNLGPGTYNPDSGDFSARAVRERSMGPDWKRAQETARLAQIPHLLYRDAWANKQFLKTKVGPGTYKIPSFTEELKKKPSSLRGICETREERF-KDCQNTSVGPGIYKITSFI---EDLEKKPGSPKGICE--TREQRFKDFQSCTPGPGAYGKGGIPSASLEEKERRNRG----NSIDSSARLKRFPENIVKRTNLGPGEYTKFGEELQRPEKKKH---GVFSSLEQYPSVPTERIYLSTLPQCPRPMTFP-GPGWYDVSPVTPSRQSRSETPAPFLSSASRFSK-SMETLLNKNHNMVGPGRYEIADKNWNSTGHS--SAFISDTQRYPNCPARDKYNQERLRPQNV 380

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007365.1 (pep scaffold:Pmarinus_7.0:GL476565:113022:120666:1 gene:ENSPMAG00000006647.1 transcript:ENSPMAT00000007365.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.0182 bits (175), Expect = 3.520e-14
Identity = 84/349 (24.07%), Postives = 149/349 (42.69%), Query Frame = 1

Query:  103 FGSSVPKFTCYGIHPKLQSTNSF----YSKSVPPN----VGPGSYNVKHQE----KSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATK--ILQSKGRRFSDDIKDCYPGPSTYGIPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNF--GNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVF------WTDPGNTPVDITNQVSPASYNLSQSLYKI-GKSKAGFGSSDIRMNKFALANFMG-ENNTLIGPGRYN 1077
            FGS+  +F   GIHP+L+   ++    Y      N    +GPG YN +       ++   R S   W  +  L +    P+F  +E  + E  +K +LGPG Y+ ++ +  L ++  +++  +  +   RF +  K   PGP +Y  P+     A      A+  P+ +   + NR        +GPG +   S  +++       RG YD     R+ P++TG   ++   +L PG       +  +    +  C  G        P++P +R+       W+ PG           P +Y+++    ++   S+  F SS  R N  +   FMG ++   +GPGRYN
Sbjct:   13 FGSATARFNVSGIHPQLKPLGTYTEAPYCSQTMSNQIRALGPGRYNPECSGGFGVRAVSRRASGPGWAREVELSRSARTPHFRHREAWEKERTQKSRLGPGIYDTKDFID-LERERPSSRRGVCDTLEERFLNIGKSSTPGPGSYVRPER--PGAAWAHHPASRGPM-ELSSSVNRSTPETGSGLGPGTHEHRSFTDELAARVVSARGPYDLFTGRRTDPLRTGW--LVAPESLWPGPRGCPQPSMAEALAARTRCRIGTV----GPPKEPAERLMEQWVKAWSWPG-----------PGTYDMNLEAREVRSASRPPFLSSSARFNSRSDRLFMGSQDQNPVGPGRYN 340

[Close]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007366.1 (pep scaffold:Pmarinus_7.0:GL476565:114349:120666:1 gene:ENSPMAG00000006647.1 transcript:ENSPMAT00000007366.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.6254 bits (161), Expect = 2.362e-12
Identity = 81/343 (23.62%), Postives = 145/343 (42.27%), Query Frame = 1

Query:  121 KFTCYGIHPKLQSTNSF----YSKSVPPN----VGPGSYNVKHQE----KSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATK--ILQSKGRRFSDDIKDCYPGPSTYGIPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNF--GNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVF------WTDPGNTPVDITNQVSPASYNLSQSLYKI-GKSKAGFGSSDIRMNKFALANFMG-ENNTLIGPGRYN 1077
            +F   GIHP+L+   ++    Y      N    +GPG YN +       ++   R S   W  +  L +    P+F  +E  + E  +K +LGPG Y+ ++ +  L ++  +++  +  +   RF +  K   PGP +Y  P+     A      A+  P+ +   + NR        +GPG +   S  +++       RG YD     R+ P++TG   ++   +L PG       +  +    +  C  G        P++P +R+       W+ PG           P +Y+++    ++   S+  F SS  R N  +   FMG ++   +GPGRYN
Sbjct:   29 RFNVSGIHPQLKPLGTYTEAPYCSQTMSNQIRALGPGRYNPECSGGFGVRAVSRRASGPGWAREVELSRSARTPHFRHREAWEKERTQKSRLGPGIYDTKDFID-LERERPSSRRGVCDTLEERFLNIGKSSTPGPGSYVRPER--PGAAWAHHPASRGPM-ELSSSVNRSTPETGSGLGPGTHEHRSFTDELAARVVSARGPYDLFTGRRTDPLRTGW--LVAPESLWPGPRGCPQPSMAEALAARTRCRIGTV----GPPKEPAERLMEQWVKAWSWPG-----------PGTYDMNLEAREVRSASRPPFLSSSARFNSRSDRLFMGSQDQNPVGPGRYN 350

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Nematostella
Match: EDO34936 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMX3])

HSP 1 Score: 154.836 bits (390), Expect = 1.173e-42
Identity = 121/394 (30.71%), Postives = 201/394 (51.02%), Query Frame = 1

Query:   91 SKSAFGSSVPKFTCYGIHPKLQSTNSF----YSK----SVPPNVGPGSYNVKH---QEKSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATK-ILQSKGRRFSDDIKDCYPGPSTYG---IPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYN---FGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAG----FGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSK---ISDPKTIDVLRSR-VRP 1194
            S + FG    +F    IHPK ++  +F    Y K     V   +GPGSYN++     +KS   R S   W+  Y   +   IP+ + KE+ + +  +KR LGPG Y +++ M+ +++   +T+   +++  RF    +   PGP TYG   IP  ++++ +  RK  ++V +LD G +  R       H+ PG Y +ES  +++ +H   +RG YD    +R++PI  G+ A+ +  NLGPG+Y+   F +E    H + H   GKFL+  ++P+ P +R++       P D  ++  P SY    S   +GK +A     FGSS  RM++ A   F+G  N  +GPGRY+ D     +  +    AF S   +   I D   ++ +R++ VRP
Sbjct:    7 SGAPFGVQTSRFDVSSIHPKSKTPGTFTQVPYDKKCMTEVNRRLGPGSYNIEAGGFNKKSVLERASGPGWERAYETSRLAKIPHLLYKEQWEKKQYQKRMLGPGTYNIKDFMELMAEKPRSTRGECETRAARFESSTQSGVPGPGTYGKGGIPNAVLEEKE--RKSVSNVGMLDSGKSYRRQLPEVGSHLCPGQYEMESFTDEMASHVVSKRGPYDLFTGERNKPITVGYFAMPLRQNLGPGEYDLKSFLSENTGEHKQRH---GKFLKVTRFPDYPTERIYCCSLSQCPRD-PSEPGPGSY----SAKDLGKPEAAKRPPFGSSAGRMDRHARRFFLGSTNP-VGPGRYSVDRYENAQHIDGHTGAFNSKTRRYDLIRDKYMMERIRAKDVRP 389

[Close]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Planmine SMEST
Match: SMESG000051172.1 (SMESG000051172.1)

HSP 1 Score: 806.209 bits (2081), Expect = 0.000e+0
Identity = 399/405 (98.52%), Postives = 400/405 (98.77%), Query Frame = 1

Query:   88 MSKSAFGSSVPKFTCYGIHPKLQSTNSFYSKSVPPNVGPGSYNVKHQEKSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGRRFSDDIKDCYPGPSTYGIPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINLPEMKKKKETHLATENSLREYHNSYENLKSLVIS 1302
            MSKSAFGSSVPKFTCYGIHPKLQSTNSFYSKSVPPNVGPGSYNVKHQEKSSKNRFSSEMWKVQY LEKQKTIPYF+IKEKKQ EAEKKRQLGPGYYEVEESMKKLSKDNHAT ILQSK RRFSDDIKDCYPGPSTYGIPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVD TNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINLPEMKKKKETHLATENSLREYHNSYENLKSLVIS
Sbjct:    1 MSKSAFGSSVPKFTCYGIHPKLQSTNSFYSKSVPPNVGPGSYNVKHQEKSSKNRFSSEMWKVQYKLEKQKTIPYFLIKEKKQTEAEKKRQLGPGYYEVEESMKKLSKDNHATTILQSKARRFSDDIKDCYPGPSTYGIPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDKTNQVSPASYNLSQSLYKIGKSKAGFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINLPEMKKKKETHLATENSLREYHNSYENLKSLVIS 405

[Close]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Planmine SMEST
Match: SMESG000035257.1 (SMESG000035257.1)

HSP 1 Score: 279.641 bits (714), Expect = 1.053e-89
Identity = 170/403 (42.18%), Postives = 227/403 (56.33%), Query Frame = 1

Query:   82 FIMSKSAFGSSVPKFTCYGIHPKLQSTNSFYSKSVPPNVGPGSYNVKH-----QEKSSKNRFSSEMWKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGRRFSDDIKDCYPGPSTYG---IPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAG----FGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINLPEMKKKKETHLATENSL 1254
            FI  +   GS+VP+F  YGIHP           SV   +GPG Y++ +     ++K  K+ F S+ W+    LE+Q  IP+FM K   + + E+KR++GPG YE + S+   S D   T  L+SK RRF +  KD +PGP TYG   IP     +AD RRK+ N+V LL RGG S R       +IGPGIY ++S I++ L H TG R +YDCN+ ++  P+K GH AIL  H++GPGQY     I   +D+FH FKGKFL+E QYP KPH+RVF+ DP NTP D  NQVS  SY      Y+   S  G    F  S +RM+K AL NF G      GPGRYN D        ++  ++F +   + S    + V+R R R  NL   K+ K  HLAT  S+
Sbjct:    4 FIDRRGFNGSTVPRFIQYGIHPNAMEKGKMGITSVDGELGPGKYDLSYTSCFDEKKLDKSSFKSD-WRRALFLEQQGKIPHFMSKYLYKEKEEQKRRMGPGKYEYK-SIFDYSNDKKYTTSLKSKSRRFVEAKKDSFPGPGTYGKFGIPDQKKYEADQRRKHCNTVGLLKRGGKSGRNFFNNINNIGPGIYQVKSVIDESLKHHTGLRNFYDCNSDEKLLPLKFGHRAILKPHDIGPGQYQHKEFITELNDRFHIFKGKFLQELQYPPKPHERVFYIDPANTPPDPRNQVSTHSYYPRNPNYRKCVSFGGKTYPFNFSSLRMDKIALENFTGNRTPFTGPGRYNIDKADASRHISAATASFNAKTPQTSSEFQLKVIRERNRGRNLIRNKEDKLDHLATTKSV 404

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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Planmine SMEST
Match: SMESG000008990.1 (SMESG000008990.1)

HSP 1 Score: 215.698 bits (548), Expect = 4.904e-65
Identity = 138/399 (34.59%), Postives = 215/399 (53.88%), Query Frame = 1

Query:   88 MSKSAFGSSVPKFTCYGIHPKLQSTNSF--YSKSVPPNVGPGSYNVKHQEKS-SKNRFSSEM----WKVQYNLEKQKTIPYFMIXXXXXXXXXXXRQLGPGYYEVEESMKKLSKDNHATKILQSKGRRFSDDIKDCYPGPSTYG---IPQDIIDQADIRRKYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGYYDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKFLREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKA-GFGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSLVSKISDPKTIDVLRSRVRPINLPEMKKKKETHLATENS 1251
             S + FG    +F   G+HPK +   +      S   N+GPG Y  + +  S S+++   +     WK  Y  E+  ++PY + K+   A+ E+KR+LGPGYY V+ S   L+K+     ++  +  RF ++ K+  PGP  YG   IP  + ++ D +RK A+++ +L  GGN  R        + P  YN+ S IN+V+NHQ+G+RG YD  +L+R++PIKTGH A+L +H L PG Y+  + +D  +   +   GKFL+  QYP+KPH R +W +P   P DI NQ++P SY++      I    A  F SS  R +K +   F  +N   +GPGRY+       +  NS E+ FKS        +   +L  R++P N+P  K+    H+ TE+S
Sbjct:    6 FSGAPFGYQSHRFDLAGVHPKRKMPGTLIGMQTSSNNNIGPGYYITEDRSSSFSQSKLDLDAKKPGWKRSYATEQFSSMPYILNKDLYLAKQEQKRKLGPGYYSVDYSTLNLNKN--VKGVMSEREPRFMEEYKEITPGPGIYGKCGIPHLLKEEGDNQRKSASTIGMLHNGGNGERTLPATGCRLAPNTYNLPSFINEVINHQSGKRGPYDIFSLNRTKPIKTGHLAVLPAHELAPGHYDSKSSVDILNSSNYKHHGKFLKMDQYPDKPHDRAYWNNPACVPPDINNQLAPGSYDVKFPQNIISHDSAPPFNSSSNRHDKLSNM-FFYQNFNQVGPGRYDLQRLQDSKYVNSHENIFKSKTGAQLTKEKFSMLSERLKPKNIPINKRHFIDHIPTESS 401

The following BLAST results are available for this feature:

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Human
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Celegans
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Fly
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Zebrafish
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Xenopus
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Mouse
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. UniProt/SwissProt
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. TrEMBL
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Cavefish
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Sea Lamprey
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Yeast
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Nematostella
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Medaka
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Planmine SMEST

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2


Match Name	E-value	Identity	Description
LEXM	2.261e-15	24.40	lymphocyte expansion molecule [Source:HGNC Symbol;...	[more]
LEXM	3.113e-15	24.40	lymphocyte expansion molecule [Source:HGNC Symbol;...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSXETT00000045218.1	5.284e-32	29.12	lymphocyte expansion molecule [Source:NCBI gene;Ac...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Lexm	5.036e-18	26.22	lymphocyte expansion molecule [Source:MGI Symbol;A...	[more]
Lexm	5.036e-18	26.22	lymphocyte expansion molecule [Source:MGI Symbol;A...	[more]
Lexm	5.036e-18	26.22	lymphocyte expansion molecule [Source:MGI Symbol;A...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3


Match Name	E-value	Identity	Description
sp\|B1H283\|LEXM_RAT	2.573e-17	26.96	Lymphocyte expansion molecule OS=Rattus norvegicus...	[more]
sp\|A2AVQ5\|LEXM_MOUSE	3.522e-17	26.22	Lymphocyte expansion molecule OS=Mus musculus OX=1...	[more]
sp\|Q3ZCV2\|LEXM_HUMAN	1.495e-14	24.40	Lymphocyte expansion molecule OS=Homo sapiens OX=9...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8HJX0	3.064e-53	34.40	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A7SMX3	8.479e-39	30.71	Predicted protein OS=Nematostella vectensis OX=453...	[more]
A0A210Q094	1.315e-34	31.38	Uncharacterized protein OS=Mizuhopecten yessoensis...	[more]
N1PB98	1.517e-32	29.75	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A1S3JSZ9	2.807e-32	29.53	lymphocyte expansion molecule OS=Lingula unguis OX...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSAMXT00000013749.2	9.815e-19	26.10	lymphocyte expansion molecule [Source:NCBI gene;Ac...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000007365.1	3.520e-14	24.07	pep scaffold:Pmarinus_7.0:GL476565:113022:120666:1...	[more]
ENSPMAT00000007366.1	2.362e-12	23.62	pep scaffold:Pmarinus_7.0:GL476565:114349:120666:1...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO34936	1.173e-42	30.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of A disintegrin and metalloproteinase with thrombospondin motifs 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000051172.1	0.000e+0	98.52	SMESG000051172.1	[more]
SMESG000035257.1	1.053e-89	42.18	SMESG000035257.1	[more]
SMESG000008990.1	4.904e-65	34.59	SMESG000008990.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30031005 ID=SMED30031005|Name=A disintegrin and metalloproteinase with thrombospondin motifs 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1366bp
AATTGTTTAAAATATTGGTTTCCAAGCAACGTTCAATAAAATTAAATTTC
AGAAAATAAAAATTTTAACTTCATATTATATTTTATCATGTCTAAATCAG
CATTTGGATCATCCGTTCCTAAATTTACATGCTACGGAATTCATCCAAAA
CTTCAGTCAACCAATAGTTTTTATTCAAAATCAGTTCCACCAAATGTTGG
ACCCGGATCTTATAATGTAAAACATCAAGAAAAATCGTCTAAAAATCGAT
TTAGTTCAGAAATGTGGAAAGTGCAATATAATCTAGAAAAACAAAAAACA
ATTCCTTACTTTATGATAAAAGAAAAAAAACAAGCAGAGGCTGAAAAGAA
AAGACAATTGGGACCGGGATATTATGAGGTAGAAGAATCTATGAAAAAGC
TCTCAAAAGATAATCACGCAACGAAAATATTACAATCAAAAGGACGAAGA
TTTTCTGATGACATAAAAGATTGCTATCCAGGTCCTTCAACCTATGGCAT
TCCACAAGACATTATAGATCAAGCGGATATTCGAAGAAAATATGCAAACT
CGGTTCCTCTCTTAGATCGTGGTGGAAATTCAAATCGTTTACCAACACCT
CCATCCTTCCATATTGGTCCTGGAATTTACAATATTGAATCTCCAATTAA
TCAAGTTTTAAATCATCAAACTGGTCAACGAGGCTATTATGACTGTAATA
ACTTAGATAGATCCCAACCTATTAAAACCGGACACCATGCAATCTTAGTT
TCACATAACCTGGGACCGGGTCAATACAATTTTGGAAATGAAATCGATAG
ATTTCATGATAAATTTCATTGTTTTAAAGGAAAGTTTCTGAGAGAAAAAC
AATATCCGGAGAAGCCACATCAAAGAGTATTTTGGACGGATCCCGGAAAT
ACACCAGTTGATATAACTAATCAAGTTAGTCCGGCTTCGTACAACTTGAG
TCAATCACTTTACAAAATTGGAAAGTCAAAAGCCGGATTTGGGTCATCAG
ATATCAGAATGAATAAATTTGCCCTTGCTAACTTCATGGGAGAAAATAAC
ACTCTGATAGGACCTGGACGATATAATTGTGATTCTAAAGGAATCGGGGA
ATCGGGAAATTCCTTTGAATCCGCCTTTAAATCTCTGGTTTCGAAAATAT
CTGATCCAAAAACTATTGATGTTCTAAGGTCTCGAGTCCGACCAATAAAT
CTTCCAGAGATGAAAAAGAAGAAAGAAACTCACTTGGCAACGGAGAATTC
ACTTAGAGAATATCACAACAGTTATGAAAATCTTAAAAGCTTGGTGATTT
CCTGAAGATGAAGATCTGTGAAATGATTTATTTATGACTTATATTTAATT
ATTTTTGAATAAAAAC

protein sequence of SMED30031005-orf-1

>SMED30031005-orf-1 ID=SMED30031005-orf-1|Name=SMED30031005-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=406bp
MSKSAFGSSVPKFTCYGIHPKLQSTNSFYSKSVPPNVGPGSYNVKHQEKS
SKNRFSSEMWKVQYNLEKQKTIPYFMIKEKKQAEAEKKRQLGPGYYEVEE
SMKKLSKDNHATKILQSKGRRFSDDIKDCYPGPSTYGIPQDIIDQADIRR
KYANSVPLLDRGGNSNRLPTPPSFHIGPGIYNIESPINQVLNHQTGQRGY
YDCNNLDRSQPIKTGHHAILVSHNLGPGQYNFGNEIDRFHDKFHCFKGKF
LREKQYPEKPHQRVFWTDPGNTPVDITNQVSPASYNLSQSLYKIGKSKAG
FGSSDIRMNKFALANFMGENNTLIGPGRYNCDSKGIGESGNSFESAFKSL
VSKISDPKTIDVLRSRVRPINLPEMKKKKETHLATENSLREYHNSYENLK
SLVIS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0007229	integrin-mediated signaling pathway
GO:0008284	positive regulation of cell proliferation
GO:0035740	CD8-positive, alpha-beta T cell proliferation
GO:1903862	positive regulation of oxidative phosphorylation

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000101	muscle cell
PLANA:0000140	anterior region of the whole animal
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR033557	LEXM

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **cellular component**
Term	Definition
GO:0005739	mitochondrion

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR033557	Lymphocyte expansion molecule	PANTHER	PTHR34914	FAMILY NOT NAMED	coord: 4..375

Main menu

A disintegrin and metalloproteinase with thrombospondin motifs 2

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Owlery

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