MFS domain-containing protein

Overview


Name	MFS domain-containing protein
Smed ID	SMED30030984
Length (bp)	1401

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of MFS domain-containing protein (SMED30030984) t-SNE clustered cells

Violin plots show distribution of expression levels for MFS domain-containing protein (SMED30030984) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of MFS domain-containing protein (SMED30030984) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for MFS domain-containing protein (SMED30030984) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030984

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30030984	h1SMcG0016134	PL05001A1F08	smed_ncbi_20240424	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30030984	h1SMcG0016134	PL030001A20E03	smed_ncbi_20240424	PMID:23079596 Forsthoefel et al., 2012
Smed sexual biotype	SMED30030984	h1SMcG0016134	Contig44506	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30030984	h1SMcG0016134	Contig44506	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30030984	h1SMcG0016134	Contig42926	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30030984	h1SMcG0016134	Contig42926	newmark_ests	PMID:29674431 Fincher et al., 2018
pharynx	SMED30030984	h1SMcG0016134	dd_Smed_v4_4285_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30030984	h1SMcG0016134	dd_Smed_v4_4285_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30030984	h1SMcG0016134	dd_Smed_v4_4285_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30030984	h1SMcG0016134	dd_Smed_v4_4285_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of MFS domain-containing protein vs. Ensembl Celegans
Match: F10G7.5 (pep chromosome:WBcel235:II:4693414:4696408:1 gene:WBGene00017369.1 transcript:F10G7.5a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F10G7.5)

HSP 1 Score: 50.447 bits (119), Expect = 1.683e-6
Identity = 60/230 (26.09%), Postives = 106/230 (46.09%), Query Frame = 3

Query:  555 QDVIQNYEVKNNVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTIS---NSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFV---TSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMN 1226
            Q      ++   V   F+ M+IF TV   +G+I +G  +     E+ ++  +      NS  RV +     Q+     F +L+L +T  +    +    Y +   Q+    F LS++ +IS   N+  R+FWG + D   ++  M I+  + ++   S+P V   ++ +     + L +S IG    G F+IFP I    F   +F++ YG L  A S+ G I  L+S +
Sbjct:  183 QGFFTQEDLLERVPYVFIVMSIFFTVFQSIGLIFIGQPEGDIHVETENLIGT------NSEIRVEQARVWPQL-RTTTFLVLFLSLTCNAVWVQLTSGLYKAYGQQFIDSDFFLSLIGSISSIFNAGSRVFWGAIADTTSYQFSMSIVCSLGAVLAFSMPLVKMVSNDVLFLATVCLMFSCIG----GTFSIFPYITHKCFSKANFSVMYGFLQCAVSVAGLIAGLISTH 401

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BLAST of MFS domain-containing protein vs. Ensembl Celegans
Match: F10G7.5 (pep chromosome:WBcel235:II:4693542:4696408:1 gene:WBGene00017369.1 transcript:F10G7.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F10G7.5)

HSP 1 Score: 50.447 bits (119), Expect = 1.683e-6
Identity = 60/230 (26.09%), Postives = 106/230 (46.09%), Query Frame = 3

Query:  555 QDVIQNYEVKNNVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTIS---NSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFV---TSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMN 1226
            Q      ++   V   F+ M+IF TV   +G+I +G  +     E+ ++  +      NS  RV +     Q+     F +L+L +T  +    +    Y +   Q+    F LS++ +IS   N+  R+FWG + D   ++  M I+  + ++   S+P V   ++ +     + L +S IG    G F+IFP I    F   +F++ YG L  A S+ G I  L+S +
Sbjct:  183 QGFFTQEDLLERVPYVFIVMSIFFTVFQSIGLIFIGQPEGDIHVETENLIGT------NSEIRVEQARVWPQL-RTTTFLVLFLSLTCNAVWVQLTSGLYKAYGQQFIDSDFFLSLIGSISSIFNAGSRVFWGAIADTTSYQFSMSIVCSLGAVLAFSMPLVKMVSNDVLFLATVCLMFSCIG----GTFSIFPYITHKCFSKANFSVMYGFLQCAVSVAGLIAGLISTH 401

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BLAST of MFS domain-containing protein vs. Ensembl Celegans
Match: F10G7.5 (pep chromosome:WBcel235:II:4693414:4696408:1 gene:WBGene00017369.1 transcript:F10G7.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F10G7.5)

HSP 1 Score: 50.447 bits (119), Expect = 2.045e-6
Identity = 60/230 (26.09%), Postives = 106/230 (46.09%), Query Frame = 3

Query:  555 QDVIQNYEVKNNVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTIS---NSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFV---TSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMN 1226
            Q      ++   V   F+ M+IF TV   +G+I +G  +     E+ ++  +      NS  RV +     Q+     F +L+L +T  +    +    Y +   Q+    F LS++ +IS   N+  R+FWG + D   ++  M I+  + ++   S+P V   ++ +     + L +S IG    G F+IFP I    F   +F++ YG L  A S+ G I  L+S +
Sbjct:  197 QGFFTQEDLLERVPYVFIVMSIFFTVFQSIGLIFIGQPEGDIHVETENLIGT------NSEIRVEQARVWPQL-RTTTFLVLFLSLTCNAVWVQLTSGLYKAYGQQFIDSDFFLSLIGSISSIFNAGSRVFWGAIADTTSYQFSMSIVCSLGAVLAFSMPLVKMVSNDVLFLATVCLMFSCIG----GTFSIFPYITHKCFSKANFSVMYGFLQCAVSVAGLIAGLISTH 415

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BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1W7RA76 (Major Facilitator-like protein 5 OS=Hadrurus spadix OX=141984 PE=4 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 5.130e-17
Identity = 111/395 (28.10%), Postives = 183/395 (46.33%), Query Frame = 3

Query:  120 GAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSAL-FQDVIQNYEVKNNVEST----------------FMYMTIFCTVMLFVGVILL---------GFXXXXXXXXSHSIYNSVKYDIFN-------SYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTIS---NSIGRIFWGFLVDIKPFK-CXXXXXXXXXXXXXXXXPFVTSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSL 1193
            G F++ LTLG FYT G+  + I  ++  + ++  +     S W+  A  LG GS M  GG ++ +IG  WT L G  +   +  L    +K+    +I TYG +  +G+GI Y   L    K FT +KGL+ GI + GYGL AL F  V  ++    NV  T                F+ +      +  +G+ILL          +   ++ E+     +  + D F        +   V    KP +++ + +F+MLW            + + Y +   Q+  D   L+ V +I+   N++GRI WG+L D   +K C++I+   + S+ L  +        +++I   W   I F   G F + PT+ A++FG KH   NYGML+TA ++
Sbjct:   15 GGFLIHLTLGTFYTFGNMNTYITSYLRKKVDSDVD--YSKSIWVNAAAMLGQGSLMMIGGILEQRIGARWTCLLGCSIFSGSIALTTFAIKRGFVAVIFTYGLISSLGLGIAYVAPLAAGMKWFTTRKGLVNGIIVGGYGLGALVFNQVQTSFLNPENVVPTNGYFDSEDILARLPDLFLLLGGTYFAVQLIGIILLYSPEDKWGESYSNLLRSEKVADETDQEETDQFTLKETPDLTLPAVDHSLKPIEVLRKKEFYMLWFSFAFNVQAMQFINTMYKAYGQQFIHDDHFLATVGSIASVFNALGRIAWGYLQDRTSYKMCMLILCAALTSLMLSLIATPNGGKPMFLI---WIVSIFFAFSGIFVLLPTVTAHIFGPKHAGTNYGMLFTAPAI 404

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BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A0H3YF10 (Slc16a-10 OS=Schmidtea mediterranea OX=79327 GN=slc16a-10 PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 7.620e-17
Identity = 109/392 (27.81%), Postives = 204/392 (52.04%), Query Frame = 3

Query:  105 YIVLLGAFVVQLTLGGFYTAGSFQSKIAHFIS-NRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQNYEVKNNV-ESTFMYMTIFCTVMLFVGVI--LLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTK-EFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQY-KIDKFTLSVVFTISNSI----GRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVTSALKI--------YIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMN 1226
            Y+ + G F+V ++LGG +T GS    I  +++ N+TN           WI G  + G G+SMS GGF++ ++G  +T++ GG ++     L    +  ++  + ++YG + G+G GI YGV +    + F +  GL+ GI LSG+G+ ++  D+I +Y + +++  ST +  +      + +G I  ++       I+   ++  SV  +  N +   TK E KPHQ+I   +FW++W I  A+++  +++       + +Y +I    L ++ T +  I    GRI WG+L D   +K ++    ++ +I   +    +   K+        + + ++W  ++ F + G F+IFP ICA +FG +HFT N+G+LYT  S    I  ++ + 
Sbjct:   13 YVAVFGGFLVHISLGGIFTYGSMFPYILQYMNLNQTNVRVVHPTDVG-WIIGMATFGRGASMSLGGFIEHRLGASFTIVTGGFIMSFGYILTYFTISLHIIPVAVSYGLIVGIGTGIAYGVAMTIPTQWFPKHPGLLSGIILSGFGIGSVGFDLIHSYFIDDDITNSTLVNPSRVPVSFIAMGCIYFMIQLIAAPLIKRPETVEESVNQNNLNIFGETTKIELKPHQLIFYVNFWIIW-ITYALNSAFSLLFILLQKMWGKYLEISDLRL-LIATCTGGIFSIFGRIIWGYLTDRFGYKIVIWTSTLLFAIMFSTFYICSEVGKLSTPNGNNRFAMYLIWVIIMFFLISGNFSIFPAICAKVFGIQHFTGNFGVLYTGYSFTAVITPIIVLR 401

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BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A443SUB7 (Major Facilitator-like protein 5 OS=Leptotrombidium deliense OX=299467 GN=B4U80_02706 PE=4 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 4.141e-16
Identity = 111/402 (27.61%), Postives = 184/402 (45.77%), Query Frame = 3

Query:  120 GAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQ------------------NYEVKNNVESTFMYMTIFCTVMLFVGVILL----------------GFXXXXXXXXSHSIYNSVKYD---IFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQY-KIDKFTLSVVFTIS--NSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVTSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCI 1205
            G F+V +TLG FYT G+  + +  ++    ++  N    TS WI  A  LG G+ M  GG+++++IG  WTVL G  +   +  L    +K+  W ++++YGF+  +GVGI Y   L    K F  +KGL+ G+T+ G+GL AL  + +Q                  +  + + V S F+ +      +  +G +L+                    K      H  Y+S +        + R   ++    + +   +F  +WL+   V+     V + Y +   Q+ + D F   V  T S  N++GRI WG L+D   F+    ++  + S  +++L F+T      ++  +W S I F   G F IFPT  A +FG  H    YGML+TA +L   I
Sbjct:   16 GGFLVHITLGTFYTLGNVNTYLTSYLRKYVDSEAN--YATSIWINAAFMLGQGTLMILGGYLETRIGARWTVLIGSSIFSGSVALTYYTIKKGFWYVVVSYGFMASLGVGIAYVAPLAAGMKWFPRRKGLVNGLTVGGFGLGALIFNQVQTAYLNPMNSPPSSDGYFEDEAILSRVPSMFILLGGVYFAIQLIGSMLIFRPPTQPDEIIFSDGRLLLIKSPQTPEHEDYSSCEDSSTGTETAERLQRQDLTAMEALRTNEFAKMWLMFALVTQGVQFVNTMYKAYGQQFIRSDHFLAFVGSTASVFNALGRILWGQLLDATSFRKTFFLMCSLFSFLMITL-FITETTGSKLLYFIWISAIFFTFSGMFVIFPTATALVFGKSHAGTIYGMLFTAPALTSLI 414

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BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1S2LR32 (MFS transporter OS=Anaerobacillus alkalilacustris OX=393763 GN=BKP37_07810 PE=4 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 8.052e-15
Identity = 108/398 (27.14%), Postives = 189/398 (47.49%), Query Frame = 3

Query:   99 QKYIVLLGAFVVQLTLGGFYTAGSF-QSKIAHFISNRTN--TSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQNYEVKN-NVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRR-------VTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSS-NFNQYKIDKFTLS---VVFTISNSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVTSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNF 1247
            ++++V++GA ++Q+ LG  Y    F Q  I  F  +R +   +F+ T+             + +     G +  KIG  W    GG  I L  G+M+      ++ + + YG +GG G+GI Y   L    K F +K+GLI G+ ++G+GL  L    I  + + N  V S F+Y+ I   V++ +G  LL               N    D  NS++        V++++ P +++  Y F++LW +    +    +V+SF         K+D  T S   +V  + N+ GRI  G + D       +I++    ++ ++ + F T     ++I V   S+IGF  GGF A+FP++ A+ +GTK+   NYG++Y A  +   +  ++     FSS F
Sbjct:    2 KRWLVVIGAILIQINLGAVYAWSLFNQPLIEKFGWDREDIVVTFSITI-----------FMLAACAFIAGRIQDKIGPRWVATIGG--ILLGLGVMLASQATTIYQLYLFYGIVGGAGIGITYVCPLSACVKWFPDKRGLISGVAVAGFGLGGLIYKPIILFLIDNFGVSSAFLYLGIIYFVLVVLGAQLLS--------------NPEAGDELNSHQSDGEALTVVSEQYSPKEMLGTYQFYLLWFMYLFGTMAGLLVISFAVDIGLELVKLDVVTASNAVMVIALFNAGGRIILGKISDNIGRINTLILMYGTTTLIMLYMSFGTMNYLTFLISV---SLIGFCFGGFLALFPSVTADFYGTKNIGANYGIMYLAYGISAFVGPIIIKYISFSSAF 369

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BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1S2MAB3 (MFS transporter OS=Anaerobacillus alkalidiazotrophicus OX=472963 GN=BKP45_01320 PE=4 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.051e-14
Identity = 111/399 (27.82%), Postives = 191/399 (47.87%), Query Frame = 3

Query:   99 QKYIVLLGAFVVQLTLGGFYTAGSF-QSKIAHFISNRTN--TSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQNYEVKN-NVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRR-------VTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSS-NFNQYKIDKFTLS---VVFTISNSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVTSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFL 1250
            ++++V++GA ++Q+ LG  Y    F Q  I  +  +R +   +F+ T+             + +     G +  KIG  W    GG  I L  G+M+      ++ + + YG +GG G+GI Y   L    K F +K+GLI G+ ++G+GL  L    I  + + N  V S F+Y+ I   V++ +G  LL               N    D  NS++        V+++F P +++  Y F++LW +    +    +V+SF         K+D  T S   +V  + N+ GRI  G + D       +I++  I ++ ++ + F T     ++I V   S+IGF  GGF A+FP+I A+ +GTK+   NYG++Y A  +   +  ++     FSS FL
Sbjct:    2 KRWLVVIGAILIQINLGAVYAWSLFNQPLIETYGWDREDIVVTFSITI-----------FMLAACAFIAGKIQDKIGPRWVATIGG--ILLGLGVMLASQATTIYQLYLFYGIIGGAGIGITYVCPLSACVKWFPDKRGLISGVAVAGFGLGGLVYKPIILFLIDNFGVSSAFLYLGIIYFVLVVLGAQLLS--------------NPEAGDELNSHQSDGEALTVVSEQFSPKEMLGTYQFYLLWFMYLFGTMAGLLVISFAVDIGLELVKLDVVTASNAVMVIALFNAGGRIILGKISDNIGRINTLILMYGITTLIMLYMSFGTMNNLTFLISV---SLIGFCFGGFLALFPSITADFYGTKNIGANYGIMYLAYGISAFVGPIIIKYISFSSAFL 370

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BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000069674.1 (SMESG000069674.1)

HSP 1 Score: 620.928 bits (1600), Expect = 0.000e+0
Identity = 407/421 (96.67%), Postives = 414/421 (98.34%), Query Frame = 3

Query:   84 MSIMQQKYIVLLGAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQNYEVKNNVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTISNSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVTSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNXXXXXXXXXXXXXXXXXXXRGKSLITHNTF 1346
            MSIMQQKYIVLLGAFVVQLTLGGFY AGSFQS+IAHFISNRTNTSFNDTMKTSTWIFGAMSLGMGSSMSFGGFMDSKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIITYGFLGGVGVGIVYGVTLGTIAKIFTEKKGLIFG+TLSGYGLSA FQDVIQNYE K NVESTF+Y+TIFCTVMLFVGVILLGFKKKIKIEESHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSS FNQYKIDKFTLSVVFTISNSIGRIFWGFLVDIKPFKCIMIILLIINSIFLVSLPFVTSALK++ II+LWYSVIGFQLGGFF IFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNAFIIAGAISLLGAILSGLFRGKSLITHNTF
Sbjct:    1 MSIMQQKYIVLLGAFVVQLTLGGFYNAGSFQSEIAHFISNRTNTSFNDTMKTSTWIFGAMSLGMGSSMSFGGFMDSKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIITYGFLGGVGVGIVYGVTLGTIAKIFTEKKGLIFGLTLSGYGLSAFFQDVIQNYEGKKNVESTFIYITIFCTVMLFVGVILLGFKKKIKIEESHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSYFNQYKIDKFTLSVVFTISNSIGRIFWGFLVDIKPFKCIMIILLIINSIFLVSLPFVTSALKLHSIIILWYSVIGFQLGGFFGIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNAFIIAGAISLLGAILSGLFRGKSLITHNTF 421

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BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000069674.1 (SMESG000069674.1)

HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0
Identity = 404/418 (96.65%), Postives = 411/418 (98.33%), Query Frame = 3

Query:   93 MQQKYIVLLGAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQNYEVKNNVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTISNSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVTSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNXXXXXXXXXXXXXXXXXXXRGKSLITHNTF 1346
            MQQKYIVLLGAFVVQLTLGGFY AGSFQS+IAHFISNRTNTSFNDTMKTSTWIFGAMSLGMGSSMSFGGFMDSKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIITYGFLGGVGVGIVYGVTLGTIAKIFTEKKGLIFG+TLSGYGLSA FQDVIQNYE K NVESTF+Y+TIFCTVMLFVGVILLGFKKKIKIEESHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSS FNQYKIDKFTLSVVFTISNSIGRIFWGFLVDIKPFKCIMIILLIINSIFLVSLPFVTSALK++ II+LWYSVIGFQLGGFF IFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNAFIIAGAISLLGAILSGLFRGKSLITHNTF
Sbjct:    1 MQQKYIVLLGAFVVQLTLGGFYNAGSFQSEIAHFISNRTNTSFNDTMKTSTWIFGAMSLGMGSSMSFGGFMDSKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIITYGFLGGVGVGIVYGVTLGTIAKIFTEKKGLIFGLTLSGYGLSAFFQDVIQNYEGKKNVESTFIYITIFCTVMLFVGVILLGFKKKIKIEESHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSYFNQYKIDKFTLSVVFTISNSIGRIFWGFLVDIKPFKCIMIILLIINSIFLVSLPFVTSALKLHSIIILWYSVIGFQLGGFFGIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNAFIIAGAISLLGAILSGLFRGKSLITHNTF 418

[Close]

BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000069668.1 (SMESG000069668.1)

HSP 1 Score: 163.696 bits (413), Expect = 4.495e-45
Identity = 175/442 (39.59%), Postives = 258/442 (58.37%), Query Frame = 3

Query:   96 QQKYIVLLGAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQN---YEVK----NNVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTK--------EFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKI-----DKFTLSVVFTIS---NSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVTSALKI---YIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNF--DFSSNFL--QNXXXXXXXXXXXXXXXXXXXRGKSLI 1331
             Q Y+++LGAF +QLTLGGFYT+G+ Q  I +F+ N +++  + TM+ S WIFG + LGMG+++S GGF++ +IG   TVL GG ++  N  LM   +K  L ++II+YG +GG G+G+ YGV+LGT  K F + KGLIFGI +SG   S++  D +Q+   Y+ K    N +  +F+ +    +V+  VG IL+  + K K EE  S   S +    +      K        E + H ++   DFW+LW+IM     +++  +S  +S FN+Y         F L V+ TI+   N  GRIFWGF +D + FK +M+I+ +  S  +  LP V S LK+        +W+ VI F L G F+IFP +C  LFG K+F  NYG+L+T+ S+ G II LV M    +FSS  L  +N  II   +S L A+L+ L+RGKS I
Sbjct:    6 NQNYLIVLGAFFIQLTLGGFYTSGNIQPIIVNFMQNYSSSQTSVTMENSVWIFGVLLLGMGAAISLGGFIEMQIGPTKTVLIGGWVMSFNICLMFVTMKSYLSIVIISYGLIGGFGMGVAYGVSLGTPLKYFPKCKGLIFGIVVSGISFSSIIFDAVQDSIIYKGKEIIMNRLPMSFLILGFIYSVIQLVGSILMKKRTKDKKEERSSQNYSPEASDGDQKLDFPKLKILNNPPELQTHHLLFVLDFWILWMIM----FLNSFCVSLITSLFNRYSAVLVNETSFNLKVIVTIAKIFNCFGRIFWGFAIDKQSFKMLMLIITLTISFMIGILP-VISTLKVSWHLPTFAVWFIVIHFFLSGTFSIFPIVCCKLFGMKYFVCNYGLLFTSCSVGGTIISLVIMLVFPEFSSTPLVFRNMVIIGVILSFLAALLTLLYRGKSAI 442

[Close]

BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000069673.1 (SMESG000069673.1)

HSP 1 Score: 155.992 bits (393), Expect = 2.144e-42
Identity = 156/424 (36.79%), Postives = 241/424 (56.84%), Query Frame = 3

Query:  102 KYIVLLGAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQNYEVKN--NVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKY-DIF-NSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTIS------NSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFVT----SALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNXXXXXXXXXXXXXXXXXXXRGKSLI 1331
            KY+ + G F++ +++G FY+AG     I  ++ N          KTSTWIFG+  LGMG++MS GG+++ KIG+  TVL GG ++  N  LM   +   L ++I+TYG   G G G+VYGV LG   KI  ++ GL  G+ +SG+G+SA   D +QN    +  N+  +F+ M     V+  +G ILL  K         S   S  Y +IF NS  ++  EFKPH+I+LE DFW+LW+       ++ I ++F ++ +N+Y  + F    + TIS      N +GRIFWGF++D KPFK  M+I+ +  SI +     ++    +     I+  + +  I F   G F IFP +CA L+G K+F  NYGML+TA S+   I+ ++SMN     + L+  F+   A+S+L  +++ ++RGKSLI
Sbjct:   10 KYLPIFGGFLLHISVGYFYSAGHIMPHINKYMKNEN--------KTSTWIFGSTLLGMGAAMSLGGYVEMKIGSSLTVLIGGWIMSANICLMCVTMTCGLTVVILTYGLFAGFGTGLVYGVALGVPLKIVKKRVGLFLGVVVSGFGVSATIFDYLQNVLSSDYTNLPLSFLIMGCIYAVIQLIGAILLKKKANENDLTIQSNETSFNYFEIFLNSKSKM--EFKPHEILLELDFWILWITF----FLNAIGVNFLTTLYNEYYHELFGAQHLVTISISGAAFNCLGRIFWGFIIDKKPFKITMVIMTVGTSILMALFSTISLMNLTGKMNEIVFGIIFCAINFFQSGNFCIFPFMCAQLYGVKYFVCNYGMLFTACSVACTIVNIISMNISREKDNLKFVFVAGAALSILSTLMTLVYRGKSLI 419

[Close]

BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000069670.1 (SMESG000069670.1)

HSP 1 Score: 150.599 bits (379), Expect = 1.654e-40
Identity = 150/429 (34.97%), Postives = 231/429 (53.85%), Query Frame = 3

Query:  102 KYIVLLGAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTMKTSTWIXXXXXXXXXXXXXXXXXXXXKIGTIWTVLFGGGLICLNTGLMITMVKQNLWLIIXXXXXXXXXXXXXXXXXXXXXXAKIFTEKKGLIFGITLSGYGLSALFQDVIQNY---EVKNNVESTFMYMTIFCTVMLFVGVILLGFXXXXXXXXSHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVDNIVMSFYSSNFNQYKIDKFTLSVVFTIS------NSIGRIFWGFLVDIKPFKCXXXXXXXXXXXXXXXXPFV-----TSALKIYIIIVLWYSVIGFQLGGFFAIFPTICANLFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNXXXXXXXXXXXXXXXXXXXRGKSLITHNTF 1346
            KY+ +LG+F++ L++G F++ G  + +I  ++ N          KTSTWI G+  LGMG++MS GG+++ KIG+  TVL GG ++  N  LM   +   L ++I+TYG   G G G+VYGV LG   +I   + GLI G+  SG+G+SAL    +QN         +  +F+ +     V+  +G IL+  K         SI  S  Y   N       EFKPH+I+LE DFW+LW+I+   +   N++   Y    N+Y  + F    + TIS      N +GRIFWGF++D KPFK  M+I+ +  SI +     +     T  +  Y+  +++ ++  FQ G F  IFP +CA L+G K+F  NYGML+TA S  G  + ++          ++  F    A+S L A+++ ++RGKSLI    F
Sbjct:   10 KYLPILGSFLLHLSVGCFFSIGQIKPQIDEYMGNNN--------KTSTWIVGSTLLGMGAAMSLGGYVEMKIGSSLTVLIGGWIMSANICLMCVTMTCGLTVVILTYGLFAGFGTGLVYGVALGVPIRIMKNRIGLIIGVVASGFGVSALIFYFLQNLFTGSCCKYLPQSFLILGCIYAVIQLIGGILIKEKANKNELAIESIERSFNYFGNNLVSYDNLEFKPHEILLELDFWILWIILFLNAICINLITCLY----NEYYHELFGAQHLVTISISGAAFNCLGRIFWGFIIDKKPFKITMVIMTVGTSILMALFATISLMNLTGKMNGYVFGIIFCAINFFQSGNF-CIFPFMCARLYGVKYFVCNYGMLFTACSAAGTTVNIILTTTSVDKEIIKTLFFTGTALSSLSAMVTIVYRGKSLIVRTNF 425

The following BLAST results are available for this feature:

BLAST of MFS domain-containing protein vs. Ensembl Human
BLAST of MFS domain-containing protein vs. Ensembl Celegans
BLAST of MFS domain-containing protein vs. Ensembl Fly
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
BLAST of MFS domain-containing protein vs. Ensembl Mouse
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
BLAST of MFS domain-containing protein vs. TrEMBL
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
BLAST of MFS domain-containing protein vs. Ensembl Yeast
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
BLAST of MFS domain-containing protein vs. Ensembl Medaka
BLAST of MFS domain-containing protein vs. Planmine SMEST

BLAST of MFS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
F10G7.5	1.683e-6	26.09	pep chromosome:WBcel235:II:4693414:4696408:1 gene:...	[more]
F10G7.5	1.683e-6	26.09	pep chromosome:WBcel235:II:4693542:4696408:1 gene:...	[more]
F10G7.5	2.045e-6	26.09	pep chromosome:WBcel235:II:4693414:4696408:1 gene:...	[more]

BLAST of MFS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1W7RA76	5.130e-17	28.10	Major Facilitator-like protein 5 OS=Hadrurus spadi...	[more]
A0A0H3YF10	7.620e-17	27.81	Slc16a-10 OS=Schmidtea mediterranea OX=79327 GN=sl...	[more]
A0A443SUB7	4.141e-16	27.61	Major Facilitator-like protein 5 OS=Leptotrombidiu...	[more]
A0A1S2LR32	8.052e-15	27.14	MFS transporter OS=Anaerobacillus alkalilacustris ...	[more]
A0A1S2MAB3	1.051e-14	27.82	MFS transporter OS=Anaerobacillus alkalidiazotroph...	[more]

BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of MFS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000069674.1	0.000e+0	96.67	SMESG000069674.1	[more]
SMESG000069674.1	0.000e+0	96.65	SMESG000069674.1	[more]
SMESG000069668.1	4.495e-45	39.59	SMESG000069668.1	[more]
SMESG000069673.1	2.144e-42	36.79	SMESG000069673.1	[more]
SMESG000069670.1	1.654e-40	34.97	SMESG000069670.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030984 ID=SMED30030984|Name=MFS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1401bp
CAATTTTTCATTAAATTTTTCATCTTTGTTATAAAATAAAAGTTTACCTA
ATTTCAAAGTTAAATCTTTTTTTCTTATAACTCATGTCGATTATGCAACA
GAAATACATTGTCCTTCTTGGTGCATTTGTTGTCCAACTGACTCTTGGCG
GTTTTTATACTGCTGGAAGTTTTCAGTCTAAAATAGCTCATTTTATATCA
AATCGTACTAATACAAGTTTTAATGACACTATGAAAACTTCAACTTGGAT
TTTTGGGGCCATGTCATTGGGAATGGGGTCTTCCATGTCTTTCGGTGGAT
TTATGGACAGTAAAATCGGCACAATCTGGACTGTCTTGTTTGGCGGTGGT
TTGATATGCTTAAATACTGGTCTTATGATTACAATGGTGAAACAAAACTT
GTGGCTTATCATCATCACTTATGGGTTTTTAGGTGGAGTTGGCGTTGGTA
TTGTATATGGAGTCACCCTGGGCACTATAGCTAAAATTTTTACAGAAAAA
AAAGGTTTAATATTTGGAATAACCTTATCAGGTTACGGATTATCAGCTTT
GTTTCAAGATGTCATACAAAATTATGAGGTGAAAAATAATGTGGAAAGCA
CTTTTATGTATATGACTATCTTTTGTACGGTCATGCTATTCGTTGGAGTC
ATCTTGTTAGGATTTAAAAAAAAAATAAAAATTGAAGAAAGTCATTCAAT
ATATAACAGTGTAAAATATGACATATTCAACAGCTATAGACGAGTTACAA
AGGAATTTAAACCTCACCAAATCATACTTGAATACGATTTTTGGATGTTA
TGGCTAATCATGACTGCCGTAAGCGCGGTAGATAATATTGTAATGTCTTT
TTATTCAAGTAATTTTAACCAATATAAGATAGATAAATTTACGTTATCTG
TGGTCTTCACCATCAGCAATTCCATTGGGAGAATATTCTGGGGTTTCCTC
GTGGACATAAAGCCGTTTAAATGCATAATGATAATTTTGCTTATCATTAA
TTCCATATTTCTCGTCTCTTTGCCATTTGTCACAAGTGCATTAAAAATAT
ATATCATCATTGTTTTATGGTATTCTGTCATTGGTTTTCAACTGGGAGGG
TTCTTTGCAATTTTCCCAACAATTTGTGCAAATTTATTTGGTACCAAACA
TTTTACTATAAATTATGGAATGCTTTATACCGCAAATTCGTTGCCCGGGT
GCATAATATGCTTGGTTTCAATGAATTTTGATTTTTCTTCAAACTTTTTG
CAGAATGCATTCATCATTGCAGGAGCAATTTCTCTACTTGGAGCAATATT
GAGTGGTTTATTCAGAGGAAAGTCGTTAATCACTCATAATACATTCTAAA
TGAAACTAATTGATATATTTTTTAATAAAAATTTGATTTATTTAAAAAAA
A

protein sequence of SMED30030984-orf-1

>SMED30030984-orf-1 ID=SMED30030984-orf-1|Name=SMED30030984-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=422bp
MSIMQQKYIVLLGAFVVQLTLGGFYTAGSFQSKIAHFISNRTNTSFNDTM
KTSTWIFGAMSLGMGSSMSFGGFMDSKIGTIWTVLFGGGLICLNTGLMIT
MVKQNLWLIIITYGFLGGVGVGIVYGVTLGTIAKIFTEKKGLIFGITLSG
YGLSALFQDVIQNYEVKNNVESTFMYMTIFCTVMLFVGVILLGFKKKIKI
EESHSIYNSVKYDIFNSYRRVTKEFKPHQIILEYDFWMLWLIMTAVSAVD
NIVMSFYSSNFNQYKIDKFTLSVVFTISNSIGRIFWGFLVDIKPFKCIMI
ILLIINSIFLVSLPFVTSALKIYIIIVLWYSVIGFQLGGFFAIFPTICAN
LFGTKHFTINYGMLYTANSLPGCIICLVSMNFDFSSNFLQNAFIIAGAIS
LLGAILSGLFRGKSLITHNTF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0022857	transmembrane transporter activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036259	MFS_trans_sf
IPR011701	MFS
IPR020846	MFS_dom

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0016020	membrane

Vocabulary: **biological process**
Term	Definition
GO:0055085	transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR011701	Major facilitator superfamily	PFAM	PF07690	MFS_1	coord: 43..374 e-value: 6.4E-21 score: 74.7
None	No IPR available	GENE3D	G3DSA:1.20.1250.20		coord: 7..203 e-value: 2.5E-8 score: 35.4
None	No IPR available	GENE3D	G3DSA:1.20.1250.20		coord: 223..414 e-value: 4.1E-15 score: 57.6
None	No IPR available	PANTHER	PTHR11360:SF3	OXALATE/FORMATE ANTIPORTER	coord: 6..405
None	No IPR available	PANTHER	PTHR11360	MONOCARBOXYLATE TRANSPORTER	coord: 6..405
None	No IPR available	CDD	cd17353	MFS_OFA_like	coord: 7..407 e-value: 1.43363E-41 score: 149.298
None	No IPR available	TMHMM	TMhelix		coord: 142..162
None	No IPR available	TMHMM	TMhelix		coord: 80..102
None	No IPR available	TMHMM	TMhelix		coord: 326..348
None	No IPR available	TMHMM	TMhelix		coord: 297..316
None	No IPR available	TMHMM	TMhelix		coord: 107..129
None	No IPR available	TMHMM	TMhelix		coord: 54..73
None	No IPR available	TMHMM	TMhelix		coord: 268..290
None	No IPR available	TMHMM	TMhelix		coord: 236..258
None	No IPR available	TMHMM	TMhelix		coord: 7..29
None	No IPR available	TMHMM	TMhelix		coord: 361..383
None	No IPR available	TMHMM	TMhelix		coord: 172..194
None	No IPR available	TMHMM	TMhelix		coord: 388..410
IPR020846	Major facilitator superfamily domain	PROSITE	PS50850	MFS	coord: 6..415 score: 12.569
IPR036259	MFS transporter superfamily	SUPERFAMILY	SSF103473	MFS general substrate transporter	coord: 6..411

Main menu

MFS domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Owlery

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