Zinc finger, C2H2-like protein

Overview


Name	Zinc finger, C2H2-like protein
Smed ID	SMED30030966
Length (bp)	1364

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Zinc finger, C2H2-like protein (SMED30030966) t-SNE clustered cells

Violin plots show distribution of expression levels for Zinc finger, C2H2-like protein (SMED30030966) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Zinc finger, C2H2-like protein (SMED30030966) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Zinc finger, C2H2-like protein (SMED30030966) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030966

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X2 cell	SMED30030966	SMESG000067725.1	SmedASXL_015540	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
neoblast	SMED30030966	SMESG000067725.1	dd_Smed_v4_5228_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Human
Match: ZFR2 (zinc finger RNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29189])

HSP 1 Score: 50.0618 bits (118), Expect = 5.206e-6
Identity = 30/111 (27.03%), Postives = 48/111 (43.24%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPS 528
            CD+C I+C+   TY  H+ G+KH K    K+  +      N    G                  ++ L C++C V+C   +    H+ GS+H+K L  +R    +   DPS
Sbjct:  273 CDICKISCAGPQTYREHLGGQKHRK----KEAAQKTGVQPNGSPRG-----------------VQAQLHCDLCAVSCTGADAYAAHIRGSKHQKGLLSHR----QQAADPS 358

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Fly
Match: Zn72D (gene:FBgn0263603 transcript:FBtr0075493)

HSP 1 Score: 49.6766 bits (117), Expect = 5.261e-6
Identity = 28/102 (27.45%), Postives = 50/102 (49.02%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYI 501
            C+VC I+C+   TY  H++G+KH K  +   +  +  +A+  +  GN                   N  CE+CDV C   +    H+ G++H+K +KL++ +
Sbjct:  207 CEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNR--GN-------------------NYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKL 287

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Fly
Match: Zn72D (gene:FBgn0263603 transcript:FBtr0333293)

HSP 1 Score: 49.2914 bits (116), Expect = 5.340e-6
Identity = 28/102 (27.45%), Postives = 50/102 (49.02%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYI 501
            C+VC I+C+   TY  H++G+KH K  +   +  +  +A+  +  GN                   N  CE+CDV C   +    H+ G++H+K +KL++ +
Sbjct:  207 CEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNR--GN-------------------NYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKL 287

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Fly
Match: Zn72D (gene:FBgn0263603 transcript:FBtr0333294)

HSP 1 Score: 49.2914 bits (116), Expect = 7.188e-6
Identity = 28/102 (27.45%), Postives = 50/102 (49.02%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYI 501
            C+VC I+C+   TY  H++G+KH K  +   +  +  +A+  +  GN                   N  CE+CDV C   +    H+ G++H+K +KL++ +
Sbjct:  207 CEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNR--GN-------------------NYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKL 287

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Fly
Match: Zn72D (gene:FBgn0263603 transcript:FBtr0310582)

HSP 1 Score: 49.2914 bits (116), Expect = 7.188e-6
Identity = 28/102 (27.45%), Postives = 50/102 (49.02%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYI 501
            C+VC I+C+   TY  H++G+KH K  +   +  +  +A+  +  GN                   N  CE+CDV C   +    H+ G++H+K +KL++ +
Sbjct:  207 CEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNR--GN-------------------NYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKL 287

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Fly
Match: Zn72D (gene:FBgn0263603 transcript:FBtr0310581)

HSP 1 Score: 49.2914 bits (116), Expect = 7.188e-6
Identity = 28/102 (27.45%), Postives = 50/102 (49.02%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYI 501
            C+VC I+C+   TY  H++G+KH K  +   +  +  +A+  +  GN                   N  CE+CDV C   +    H+ G++H+K +KL++ +
Sbjct:  207 CEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNR--GN-------------------NYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKL 287

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Zebrafish
Match: zfr2 (zinc finger RNA binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-070705-184])

HSP 1 Score: 54.299 bits (129), Expect = 2.749e-7
Identity = 29/99 (29.29%), Postives = 50/99 (50.51%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CD+C I+C+   TY  H++G+KH K   ++   ++G   +N                  G    ++ L CE+CDV+C   +    H+ GS+H+K +KL+
Sbjct:  322 CDICKISCAGPQTYREHLEGQKHKK---KEAAQKSGSQVTN------------------GPRGVQTQLRCELCDVSCTGADAYAAHIRGSKHQKVVKLH 399

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Zebrafish
Match: zfr (zinc finger RNA binding protein [Source:NCBI gene;Acc:321659])

HSP 1 Score: 51.2174 bits (121), Expect = 2.229e-6
Identity = 32/99 (32.32%), Postives = 52/99 (52.53%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K           K A+  KV  +        S  +G   +++ L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  304 CDVCKISCAGPQTYKEHLEGQKHKK-----------KEAA-LKVSQSSSSSSGGGSSARG---TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 387

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Zebrafish
Match: zfr (zinc finger RNA binding protein [Source:NCBI gene;Acc:321659])

HSP 1 Score: 51.2174 bits (121), Expect = 2.318e-6
Identity = 32/99 (32.32%), Postives = 52/99 (52.53%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K           K A+  KV  +        S  +G   +++ L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  326 CDVCKISCAGPQTYKEHLEGQKHKK-----------KEAA-LKVSQSSSSSSGGGSSARG---TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 409

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Zebrafish
Match: zfr (zinc finger RNA binding protein [Source:NCBI gene;Acc:321659])

HSP 1 Score: 51.2174 bits (121), Expect = 2.524e-6
Identity = 32/99 (32.32%), Postives = 52/99 (52.53%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K           K A+  KV  +        S  +G   +++ L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  326 CDVCKISCAGPQTYKEHLEGQKHKK-----------KEAA-LKVSQSSSSSSGGGSSARG---TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 409

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Xenopus
Match: ca12 (carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE-1015246])

HSP 1 Score: 57.7658 bits (138), Expect = 3.024e-8
Identity = 31/99 (31.31%), Postives = 52/99 (52.53%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K  +     +N  T+S+  V G                 +++ L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  326 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQN-TTSSSTAVRG-----------------TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 406

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Xenopus
Match: ca12 (carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE-1015246])

HSP 1 Score: 57.3806 bits (137), Expect = 4.356e-8
Identity = 31/98 (31.63%), Postives = 51/98 (52.04%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKL 489
            CDVC I+C+   TY  H++G+KH K  +     +N  T+S+  V G                 +++ L CE+CDV+C   +    H+ G++H+K +KL
Sbjct:  311 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQN-TTSSSTAVRG-----------------TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKL 390

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Xenopus
Match: ca12 (carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE-1015246])

HSP 1 Score: 57.3806 bits (137), Expect = 4.360e-8
Identity = 31/98 (31.63%), Postives = 51/98 (52.04%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKL 489
            CDVC I+C+   TY  H++G+KH K  +     +N  T+S+  V G                 +++ L CE+CDV+C   +    H+ G++H+K +KL
Sbjct:  334 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQN-TTSSSTAVRG-----------------TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKL 413

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Xenopus
Match: ca12 (carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE-1015246])

HSP 1 Score: 57.3806 bits (137), Expect = 4.437e-8
Identity = 31/99 (31.31%), Postives = 52/99 (52.53%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K  +     +N  T+S+  V G                 +++ L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  326 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQN-TTSSSTAVRG-----------------TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 406

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Xenopus
Match: ca12 (carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE-1015246])

HSP 1 Score: 57.3806 bits (137), Expect = 4.474e-8
Identity = 31/98 (31.63%), Postives = 51/98 (52.04%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKL 489
            CDVC I+C+   TY  H++G+KH K  +     +N  T+S+  V G                 +++ L CE+CDV+C   +    H+ G++H+K +KL
Sbjct:  333 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQN-TTSSSTAVRG-----------------TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKL 412

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Mouse
Match: Zfr2 (zinc finger RNA binding protein 2 [Source:MGI Symbol;Acc:MGI:2143792])

HSP 1 Score: 55.0694 bits (131), Expect = 1.502e-7
Identity = 55/240 (22.92%), Postives = 94/240 (39.17%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYI--ELRNNKDPSVFCDICESFMNEESMNMHRASGKH---------KRKSSAEVKDEPAEKK---ARSAD-IPT--TVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKH 864
            C+VC ++C+   TY  H++G+KH K    K   +   T  +    G+                   +L C +C V+C   +    H+ G+RH+K  KL+  +   + +   P        S    E+   H A  +H           K SA  +  P E +    R  D  P+   VE           +S  +A   T+      ++  +     C +C+ SF +++  D+HLTG +H
Sbjct:  207 CEVCRVSCAGPQTYRDHLEGQKHRK----KQAAQRTSTQPSGGPRGSQ------------------SLHCGLCAVSCTGADAYAAHMRGARHQKVFKLHTRLGKPIPSEPTPRSVTYTRGSDSTPETSVKHEAHARHSSHTQGRPAPAKGSAASRKGPPELQTMHGRPGDRRPSHFKVEATRGGPGEASGSSGDMAPVGTEYVEEVCSDEGKVIRFRCKLCECSFNDRNARDMHLTGRRH 424

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Mouse
Match: Zfp346 (zinc finger protein 346 [Source:MGI Symbol;Acc:MGI:1349417])

HSP 1 Score: 50.0618 bits (118), Expect = 2.455e-6
Identity = 44/153 (28.76%), Postives = 62/153 (40.52%), Query Frame = 1

Query:  190 VQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKL----NRYIELRNNK---DPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVK 627
             QC VC     S++    H + KKH   + R  L  +G       V+  D       SDQ+       N  C IC++    P   + H  G  H K LKL     +   L+ N+   DP  FC +C S  N+ +M      GK  RK   ++K
Sbjct:   73 TQCKVCCAMLISESQKLAHYQSKKHANKVKRY-LAIHGMETIKGDVKRLD-------SDQKSSRSKDKNHCCPICNMTFSSPAVAQSHYLGKTHAKSLKLKQQSTKGAALQQNREMLDPDKFCSLCHSTFNDPAMAQQHYMGKRHRKQETKLK 217

[Close]

BLAST of Zinc finger, C2H2-like protein vs. UniProt/SwissProt
Match: sp|Q5U231|ZFR_XENTR (Zinc finger RNA-binding protein OS=Xenopus tropicalis OX=8364 GN=zfr PE=2 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 2.370e-7
Identity = 31/98 (31.63%), Postives = 51/98 (52.04%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKL 489
            CDVC I+C+   TY  H++G+KH K  +     +N  T+S+  V G                 +++ L CE+CDV+C   +    H+ G++H+K +KL
Sbjct:  333 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQN-TTSSSTAVRG-----------------TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKL 412

[Close]

BLAST of Zinc finger, C2H2-like protein vs. UniProt/SwissProt
Match: sp|Q6GPM1|ZFR_XENLA (Zinc finger RNA-binding protein OS=Xenopus laevis OX=8355 GN=zfr PE=2 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 2.490e-7
Identity = 31/99 (31.31%), Postives = 52/99 (52.53%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K  +     +N  T+S+  V G                 +++ L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  324 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQN-TTSSSTAVRG-----------------TQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 404

[Close]

BLAST of Zinc finger, C2H2-like protein vs. TrEMBL
Match: A0A1I8F384 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 5.279e-12
Identity = 74/274 (27.01%), Postives = 110/274 (40.15%), Query Frame = 1

Query:  283 KDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEV-------KDEPAEKKARSADI---------------PTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFEL------------------------WCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEG-AFGERLMKMRAKLQSLKQSR 963
            K  F NG   +N+ V       PV+               CE+CD  C      + H EGS+H KK K  ++ EL   KDP V+CDIC   ++ E M  HRA  KH++ ++  +       K  P  K A    I               P           + + A+ A A   TQ+ A+  + RS+  EL                         C+VC I+ T+Q  ++ HL G++H +R   G   PEG  F  + MK +  + S ++ R
Sbjct:   66 KRKFNNGLGRNNSSVVVAPQRPPVQ------------QFHCELCDAKCTGEAMFKLHREGSKHLKKEKEKKFRELSEAKDPEVYCDICNLTLHPELMKSHRAGVKHRKAAAGALNRGGSGAKKSPTGKSALPPGIYRLDPAKSAADKDKPPGGATEASSSSAANETAATADAQNGTQQQAI--STRSKRAELHFNSKAHRMAFQKLQRDQIRSKGFVCEVCDIAVTSQDLMEAHLKGYRHALR-QHGGYIPEGHEFYAKYMKRQEAMLSYRKIR 324

[Close]

BLAST of Zinc finger, C2H2-like protein vs. TrEMBL
Match: A0A1B6KD30 (Uncharacterized protein OS=Graphocephala atropunctata OX=36148 GN=g.23702 PE=4 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 2.912e-11
Identity = 69/268 (25.75%), Postives = 117/268 (43.66%), Query Frame = 1

Query:  190 VQCDVCNITCSSQTTYDFHIKGKKHTKALSRK---------------DLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVF-CDICE-SFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRS---RNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMR 933
            ++CD C++   SQ     H+  KKH K + +                D+  N +      ++G    D VE +  + +        CEIC++  +  +QL+ HL G +H++K      +E  N K+   F C++C+   +++E + +H A  KHK K  AE ++  +  +A   D P     C  C +SL        H  +++H   +  R     N ++ CDVC +SFT+      H+ G KH  +    N+    A G     MR
Sbjct:  233 IKCDFCDVRFVSQDQLLVHLASKKHQKKVEKPIPKVEEFQVFDCKICDVKVNSQDQLQIHLDGKKHKDKVEKAKPKAEQFQ--GFECEICEIKVVSQDQLQIHLAGKKHKEK------VEKANPKEEVWFQCELCDVKAVSQEQLQIHLAGKKHKDK--AEKRNVNSSSEAEKPDRPFK---CDICEVSLSTKDLFELHTYSKRHVKALLKREMLESNTDV-CDVCNLSFTSIEHYQAHIQGRKHQKKCKETNNTLMTAPGSHGTCMR 486

HSP 2 Score: 64.3142 bits (155), Expect = 3.078e-7
Identity = 73/301 (24.25%), Postives = 122/301 (40.53%), Query Frame = 1

Query:  148 QYRSPYVTNKKTIPVQ---CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRK----------KLKLNRYIELRNNK-------------DPSV--------FCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTN---RSRNFELW-CDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRA 936
            QYRS     + TI  Q   C +C +  SS      H  GK+H K ++R      GKT S         M  +E      +  + ++  CE+CDV  +       H  G  HRK          K K+   I++ N++              P V        FCD+   F++++ + +H AS KH++K    +   P  ++ +  D       C  C + + +      H   +KH   +     ++  F+ + C++C+I   +Q  L +HL G KH  +V + N   E  F   L  ++A
Sbjct:   84 QYRSSSYPKELTILFQALDCRLCLVELSSPIVAKMHYSGKQHMKKVTRFLTEWCGKTGS--------AMPQIEEVTVASRTTAFADY-CELCDVRMITTNDKMLHYTGKNHRKNEKDPDNAKKKKKVYDTIDVSNSRFGIGADFSTEEEEKPKVEFQVIKCDFCDV--RFVSQDQLLVHLASKKHQKKVEKPI---PKVEEFQVFD-------CKICDVKVNSQDQLQIHLDGKKHKDKVEKAKPKAEQFQGFECEICEIKVVSQDQLQIHLAGKKHKEKVEKANPKEEVWFQCELCDVKA 363

[Close]

BLAST of Zinc finger, C2H2-like protein vs. TrEMBL
Match: A0A146LF11 (Zinc finger protein 346 OS=Lygus hesperus OX=30085 GN=znf346_1 PE=4 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 5.187e-11
Identity = 55/216 (25.46%), Postives = 94/216 (43.52%), Query Frame = 1

Query:  187 PVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDL--FENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVF--------CDICESFMNEESMNMHRASG-KHKRKSSAEVKDEPAEKKARSADIPTTVE-HCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWC 798
            P++CD+CN+ C    +Y  H++G++H   L + D     NG+T   AK                G +L +  + CE+CD+ CL  EQLE HL+G +H K+ K+    E+  +  P +         C IC   +  + + +   SG KH+RK+           K      PT     C  C + +    +++   +  K +L   ++   +  WC
Sbjct:   27 PIKCDLCNVWCQGVVSYQSHLQGRQHFANLKKPDGDGEANGQTPKKAK------------KRPSGTVLEE--VRCEVCDLTCLGKEQLEVHLQGIKHAKRAKMTEKEEIDISTLPFIKELGGKAYQCTICNVEVTGKLVVISHISGAKHQRKADPNTPKIEITGKNNKTTTPTGEPLECKVCKLPV----NSLFQLEEHKRSLKHKHKEEAYNKWC 224

[Close]

BLAST of Zinc finger, C2H2-like protein vs. TrEMBL
Match: A0A3B6RI48 (Uncharacterized protein OS=Triticum aestivum OX=4565 PE=4 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 6.150e-11
Identity = 70/285 (24.56%), Postives = 118/285 (41.40%), Query Frame = 1

Query:   97 NHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDC----------------------MDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSV---FCDICESFMNEES-MNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFEL--W-CDVCQISFTNQSFLDLHLTGFKH 864
            NH     H+    AL    + P V+        C +CN  C+SQ+  + H++G++H + +  + L  +GK   + +V G  C                       + +E  +  G+    S  MC IC+ NC      E H  G RH++ ++  +      +KDP V    CDIC +    +S    H    +H+    A+ +D          D   +   C  C+ +  + SD  +H + ++H  N+    +  E   W CD+C  + T+QS L  HL G +H
Sbjct:  245 NHLRGRRHQQNIEALQGDGKDPEVSR-----WMCSICNANCTSQSDLESHLRGRRHQENI--EALQGDGK---DPEVSGWMCDICNANCTSQSDXXXXXXXXXHQEKIEALEGDGKDPEVSRWMCYICNANCTSQSDFESHFRGRRHQENIEALQG----GDKDPEVSRWMCDICNANCTSQSDFESHLRGRRHQENIEAQQRD--------GKDPELSRWMCDICNANCTSQSDFESHLRGRRHQENIEADDKGTEASRWMCDICNANCTSQSDLKSHLRGRRH 507

HSP 2 Score: 70.4774 bits (171), Expect = 3.922e-9
Identity = 62/248 (25.00%), Postives = 101/248 (40.73%), Query Frame = 1

Query:  160 PYVTNKKTIPVQ---CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSV---FCDICESFMNEES-MNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKH-----ALNMTNRSRNFELW-CDVCQISFTNQSFLDLHLTGFKH 864
            P + +K   P+    C +C+  C+SQ+    H++G++H +               N +    D  DP             S  MC IC+ NC     LE HL G RH++ ++  +     + KDP V    CDIC +    +S          H+ K  A   D          D   +   C  C+ +  + SD  +H++ ++H     AL   ++      W CD+C  + T+QS  + HL G +H
Sbjct:  215 PQLADKNLKPMPTWFCSICDANCTSQSDLKNHLRGRRHQQ---------------NIEALQGDGKDP-----------EVSRWMCSICNANCTSQSDLESHLRGRRHQENIEALQG----DGKDPEVSGWMCDICNANCTSQSDXXXXXXXXXHQEKIEALEGD--------GKDPEVSRWMCYICNANCTSQSDFESHFRGRRHQENIEALQGGDKDPEVSRWMCDICNANCTSQSDFESHLRGRRH 424

HSP 3 Score: 63.1586 bits (152), Expect = 7.751e-7
Identity = 57/249 (22.89%), Postives = 99/249 (39.76%), Query Frame = 1

Query:   22 VSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEES-MNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNM 765
            VS + C  CN    +     Q  F +H     H+    AL    + P V+        CD+CN  C+SQ+ ++ H++G++H +               N + +  D  DP             S  MC+IC+ NC      E HL G RH++ ++ +     +  +     CDIC +    +S +  H    +H+    A   D    + +R          C  C+ +  + SD  +H + ++H  N+
Sbjct:  354 VSRWMCYICNANCTS-----QSDFESHFRGRRHQENIEALQGGDKDPEVSR-----WMCDICNANCTSQSDFESHLRGRRHQE---------------NIEAQQRDGKDP-----------ELSRWMCDICNANCTSQSDFESHLRGRRHQENIEADD----KGTEASRWMCDICNANCTSQSDLKSHLRGRRHQENIEALQGDGKGTEVSRWM--------CNICNANCLSRSDFESHIRGRRHQSNL 554

[Close]

BLAST of Zinc finger, C2H2-like protein vs. TrEMBL
Match: A0A0K8T0Q1 (C2H2-type domain-containing protein OS=Lygus hesperus OX=30085 PE=4 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 6.151e-11
Identity = 54/216 (25.00%), Postives = 94/216 (43.52%), Query Frame = 1

Query:  187 PVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLF--ENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVF--------CDICESFMNEESMNMHRASG-KHKRKSSAEVKDEPAEKKARSADIPTTVE-HCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWC 798
            P++CD+CN+ C    +Y  H++G++H   L + +     NG+T   AK                G +L +  + CE+CD+ CL  EQLE HL+G +H K+ K+    E+  +  P +         C IC   +  + + +   SG KH+RK+           K      PT     C  C + +    +++   +  K +L   ++   +  WC
Sbjct:   27 PIKCDLCNVWCQGVVSYQSHLQGRQHFANLKKPEGVGEANGQTPKKAK------------KRPSGTVLEE--VRCEVCDLTCLGKEQLEVHLQGIKHAKRAKMTEKEEIDISTLPFIKELGGKAYQCTICNVEVTGKLVVISHISGAKHQRKADPNTPKIEITGKNNKTTTPTGEPLECKVCKLPV----NSLFQLEEHKRSLKHKHKEEAYNKWC 224

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Cavefish
Match: zfr2 (zinc finger RNA-binding protein-like [Source:NCBI gene;Acc:103035531])

HSP 1 Score: 58.5362 bits (140), Expect = 9.507e-9
Identity = 61/260 (23.46%), Postives = 99/260 (38.08%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVK---------------DEPAEKKARS----------ADIPTTVEHCGYCHMSLKNASD-------AIAHYQTQKHALNMTNRSRN-----FELWCDVCQISFTNQSFLDLHLTGFKH 864
            CD+C I+C+   TY  H++G+KH K  + +   ++G  A+N    G                  ++ L CE+CDV+C   +    H+ G++H+K +KL+  +       PS         +N   + +   SGK    + A                   +PA+K A S          A  P  VE      ++    SD       A    Q   H  +     RN         C +C+ SF + +  D+HL G +H
Sbjct:  315 CDICKISCAGPQTYREHLEGQKHKKKEASQ---KSGSQATNGPRGG-----------------VQTQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKL---GKPIPSTE----PVLVNSAPVPVTTTSGKPTAPAVAPASPRVPQKPIEPNPTKGPQPAKKPALSKASVIANKAAAPEPVKVEEVKLAVLNQDPLSDDEGDSCGAQGDIQPVGH--DYVEEVRNDDGKVIRFHCKLCECSFNDPNAKDMHLKGRRH 545

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Cavefish
Match: znf346 (zinc finger protein 346 [Source:NCBI gene;Acc:103029588])

HSP 1 Score: 50.447 bits (119), Expect = 1.419e-6
Identity = 44/148 (29.73%), Postives = 60/148 (40.54%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGK--TASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVF---------CDICESFMNE-ESMNMHRASGKHK 603
            C VCN+T SS    + H +GK H K L  K+L           AKV   D    V+ +   GQ     N  C IC  +   P   ++H EG +H+K L   + +E      PS           C +C   +N  E    H +  KHK
Sbjct:   99 CTVCNMTFSSAVVAESHYQGKVHAKNLKLKNLGPQTPVFVQPKAKVNKGD----VQTAGGPGQ---DPNRFCSICQASFNNPLMAQQHYEGKKHKKHLTKQKLMETYG---PSTAPASTLKGYPCTVCNIELNSVEQYQAHISGSKHK 236

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Cavefish
Match: znf346 (zinc finger protein 346 [Source:NCBI gene;Acc:103029588])

HSP 1 Score: 50.447 bits (119), Expect = 1.766e-6
Identity = 44/148 (29.73%), Postives = 60/148 (40.54%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGK--TASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVF---------CDICESFMNE-ESMNMHRASGKHK 603
            C VCN+T SS    + H +GK H K L  K+L           AKV   D    V+ +   GQ     N  C IC  +   P   ++H EG +H+K L   + +E      PS           C +C   +N  E    H +  KHK
Sbjct:   99 CTVCNMTFSSAVVAESHYQGKVHAKNLKLKNLGPQTPVFVQPKAKVNKGD----VQTAGGPGQ---DPNRFCSICQASFNNPLMAQQHYEGKKHKKHLTKQKLMETYG---PSTAPASTLKGYPCTVCNIELNSVEQYQAHISGSKHK 236

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Cavefish
Match: zfr (zinc finger RNA binding protein [Source:NCBI gene;Acc:103021415])

HSP 1 Score: 50.447 bits (119), Expect = 3.489e-6
Identity = 32/99 (32.32%), Postives = 51/99 (51.52%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K           K A+  KV  +        S  +G   +++ L CE+CDV C   +    H+ G++H+K +KL+
Sbjct:  303 CDVCKISCAGPQTYKEHLEGQKHKK-----------KEAA-LKVSQSSSSSSGGSSSARG---TQNQLRCELCDVACTGADAYAAHIRGAKHQKVVKLH 386

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003273.1 (pep scaffold:Pmarinus_7.0:GL476625:194967:224286:-1 gene:ENSPMAG00000002991.1 transcript:ENSPMAT00000003273.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.595 bits (109), Expect = 6.961e-6
Identity = 28/103 (27.18%), Postives = 45/103 (43.69%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASN-------AKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKL 483
            C +C +  +SQ+  D H  G +H   L  KD+  +G+           AK  G+    P +            N  C++CDV      QL++H++  RH+ KL
Sbjct:  166 CTICKVAVNSQSQLDAHNNGARHKATLEGKDVRASGRPFPRHMGRNKAAKATGSMPGTPTK------------NFQCQLCDVKVNSEVQLQQHIKSRRHKDKL 256

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Medaka
Match: zfr (zinc finger RNA binding protein [Source:NCBI gene;Acc:101166968])

HSP 1 Score: 50.447 bits (119), Expect = 3.328e-6
Identity = 30/102 (29.41%), Postives = 47/102 (46.08%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTK---ALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K   AL       +    + A+   N                    L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  322 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKVSQSSSSTGGGAMARSAQN-------------------QLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 404

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Medaka
Match: zfr (zinc finger RNA binding protein [Source:NCBI gene;Acc:101166968])

HSP 1 Score: 50.447 bits (119), Expect = 3.395e-6
Identity = 30/102 (29.41%), Postives = 47/102 (46.08%), Query Frame = 1

Query:  196 CDVCNITCSSQTTYDFHIKGKKHTK---ALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLN 492
            CDVC I+C+   TY  H++G+KH K   AL       +    + A+   N                    L CE+CDV+C   +    H+ G++H+K +KL+
Sbjct:  322 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKVSQSSSSTGGGAMARSAQN-------------------QLRCELCDVSCTGADAYAAHIRGAKHQKVVKLH 404

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Planmine SMEST
Match: SMESG000067725.1 (SMESG000067725.1)

HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0
Identity = 333/344 (96.80%), Postives = 335/344 (97.38%), Query Frame = 1

Query:    1 MNNMYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRAKLQSLKQSRKEKKSSNDEKCSIVPSEQPQNEP 1032
            MNNMYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRAKLQSLKQSRKEKKSSNDEK  + P    +  P
Sbjct:    1 MNNMYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRAKLQSLKQSRKEKKSSNDEKRQLCPVRNRKMSP 344

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Planmine SMEST
Match: SMESG000067725.1 (SMESG000067725.1)

HSP 1 Score: 689.108 bits (1777), Expect = 0.000e+0
Identity = 330/341 (96.77%), Postives = 332/341 (97.36%), Query Frame = 1

Query:   10 MYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRAKLQSLKQSRKEKKSSNDEKCSIVPSEQPQNEP 1032
            MYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRAKLQSLKQSRKEKKSSNDEK  + P    +  P
Sbjct:    1 MYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRAKLQSLKQSRKEKKSSNDEKRQLCPVRNRKMSP 341

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Planmine SMEST
Match: SMESG000074376.1 (SMESG000074376.1)

HSP 1 Score: 520.005 bits (1338), Expect = 0.000e+0
Identity = 253/345 (73.33%), Postives = 285/345 (82.61%), Query Frame = 1

Query:    1 MNNMYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDC-MDPVEYSD--QQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPEGAFGERLMKMRAKLQSLKQSRKEKKSSNDEKCSIVPSEQPQN 1026
            M+N Y N+SSY CVACNIYFNNFDEQKQH F  HS S+DHESL S+LYSQYR    TNKK IPVQCD CNI+CSSQTTYDFHIKGK+HTK L++K L E  K  +    E N    D V+     QQ QIL K NLMCEIC VNC  PEQ E+HLEG RH+K+LKLNRYIEL+NNKDPSV+CDIC+  MNE+SM +HRASGKHKRKS+ EVKDEPAEKK ++ADI TTVEHCGYCH+SLK+A+DAIAHYQTQKHALNMTNRSRN+ELWC +CQISFTNQ+FLDLHL GFKHFVR+NRGN APEGAFGERL+KMRAKLQ+LKQSRK KKSSN   C I+ +EQ QN
Sbjct:    1 MHNSYVNLSSYRCVACNIYFNNFDEQKQHYFTYHSRSFDHESLTSSLYSQYRPLSATNKKVIPVQCDACNISCSSQTTYDFHIKGKRHTKTLTKKALSEIDKATNFTNFEENRISTDSVQIPAIIQQSQILYKPNLMCEICTVNCPNPEQYEKHLEGLRHQKRLKLNRYIELKNNKDPSVYCDICDLLMNEDSMTLHRASGKHKRKSTVEVKDEPAEKKTKNADIHTTVEHCGYCHVSLKSANDAIAHYQTQKHALNMTNRSRNYELWCGICQISFTNQNFLDLHLAGFKHFVRLNRGNQAPEGAFGERLIKMRAKLQNLKQSRKAKKSSNLANCQILSNEQSQN 345

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Planmine SMEST
Match: SMESG000074376.1 (SMESG000074376.1)

HSP 1 Score: 266.929 bits (681), Expect = 7.352e-88
Identity = 134/199 (67.34%), Postives = 152/199 (76.38%), Query Frame = 1

Query:    1 MNNMYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQYRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDC-MDPVEYSD--QQGQILSKSNLMCEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRA 588
            M+N Y N+SSY CVACNIYFNNFDEQKQH F  HS S+DHESL S+LYSQYR    TNKK IPVQCD CNI+CSSQTTYDFHIKGK+HTK L++K L E  K  +    E N    D V+     QQ QIL K NLMCEIC VNC  PEQ E+HLEG RH+K+LKLNRYIEL+NNKDPSV+CDIC+  MNE+SM +HRA
Sbjct:    1 MHNSYVNLSSYRCVACNIYFNNFDEQKQHYFTYHSRSFDHESLTSSLYSQYRPLSATNKKVIPVQCDACNISCSSQTTYDFHIKGKRHTKTLTKKALSEIDKATNFTNFEENRISTDSVQIPAIIQQSQILYKPNLMCEICTVNCPNPEQYEKHLEGLRHQKRLKLNRYIELKNNKDPSVYCDICDLLMNEDSMTLHRA 199

[Close]

BLAST of Zinc finger, C2H2-like protein vs. Planmine SMEST
Match: SMESG000067728.1 (SMESG000067728.1)

HSP 1 Score: 144.821 bits (364), Expect = 1.884e-39
Identity = 87/281 (30.96%), Postives = 147/281 (52.31%), Query Frame = 1

Query:  187 PVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFENGKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLM-----------------CEICDVNCLRPEQLERHLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKHKRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQKHALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPE-GAFGERLMKMRAKLQSLK-QSRKEK 972
            P  C++C I+C+S++ YD H +GKKH +AL +    +      + K+  ND    + +       +++ N++                 C+ICD++C     L+ HL G++H++KLK     +L  NKDP V+C+ICE  +    M +H+ S KHK+ +  E+   P  K          +E CG C  SL   SDA+ HY ++ H L +   + N   WC++C+I+  ++S L++HL GF+H+  +NR     + G + E+++  R K + L+ Q  KEK
Sbjct:   40 PHNCEICKISCNSKSIYDIHTEGKKHKRALEKLSELKFPCDLCSQKL--NDYNTWITHLSSHEHRIAELNILSSTTCNLPRTTLNKINRCDICDLDCGSNIILQSHLTGAKHKRKLKQLNMEKLAENKDPKVYCEICEICLEPNLMMLHKQSNKHKKVNVKEIIINPRSKSG--------MEFCGLCDQSLSGISDAVDHYNSENH-LKLVKNNEN-SCWCNICKITLPDESLLEIHLKGFRHYRILNREECISKTGTYKEKMLYKRMKQKELRVQYEKEK 308

The following BLAST results are available for this feature:

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Human
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Celegans
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Fly
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Zebrafish
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Xenopus
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Mouse
BLAST of Zinc finger, C2H2-like protein vs. UniProt/SwissProt
BLAST of Zinc finger, C2H2-like protein vs. TrEMBL
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Cavefish
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Sea Lamprey
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Yeast
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Nematostella
BLAST of Zinc finger, C2H2-like protein vs. Ensembl Medaka
BLAST of Zinc finger, C2H2-like protein vs. Planmine SMEST

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ZFR2	5.206e-6	27.03	zinc finger RNA binding protein 2 [Source:HGNC Sym...	[more]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Zn72D	5.261e-6	27.45	gene:FBgn0263603 transcript:FBtr0075493	[more]
Zn72D	5.340e-6	27.45	gene:FBgn0263603 transcript:FBtr0333293	[more]
Zn72D	7.188e-6	27.45	gene:FBgn0263603 transcript:FBtr0333294	[more]
Zn72D	7.188e-6	27.45	gene:FBgn0263603 transcript:FBtr0310582	[more]
Zn72D	7.188e-6	27.45	gene:FBgn0263603 transcript:FBtr0310581	[more]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
zfr2	2.749e-7	29.29	zinc finger RNA binding protein 2 [Source:ZFIN;Acc...	[more]
zfr	2.229e-6	32.32	zinc finger RNA binding protein [Source:NCBI gene;...	[more]
zfr	2.318e-6	32.32	zinc finger RNA binding protein [Source:NCBI gene;...	[more]
zfr	2.524e-6	32.32	zinc finger RNA binding protein [Source:NCBI gene;...	[more]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ca12	3.024e-8	31.31	carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE...	[more]
ca12	4.356e-8	31.63	carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE...	[more]
ca12	4.360e-8	31.63	carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE...	[more]
ca12	4.437e-8	31.31	carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE...	[more]
ca12	4.474e-8	31.63	carbonic anhydrase XII [Source:Xenbase;Acc:XB-GENE...	[more]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Zfr2	1.502e-7	22.92	zinc finger RNA binding protein 2 [Source:MGI Symb...	[more]
Zfp346	2.455e-6	28.76	zinc finger protein 346 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of Zinc finger, C2H2-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2


Match Name	E-value	Identity	Description
sp\|Q5U231\|ZFR_XENTR	2.370e-7	31.63	Zinc finger RNA-binding protein OS=Xenopus tropica...	[more]
sp\|Q6GPM1\|ZFR_XENLA	2.490e-7	31.31	Zinc finger RNA-binding protein OS=Xenopus laevis ...	[more]

BLAST of Zinc finger, C2H2-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8F384	5.279e-12	27.01	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1B6KD30	2.912e-11	25.75	Uncharacterized protein OS=Graphocephala atropunct...	[more]
A0A146LF11	5.187e-11	25.46	Zinc finger protein 346 OS=Lygus hesperus OX=30085...	[more]
A0A3B6RI48	6.150e-11	24.56	Uncharacterized protein OS=Triticum aestivum OX=45...	[more]
A0A0K8T0Q1	6.151e-11	25.00	C2H2-type domain-containing protein OS=Lygus hespe...	[more]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
zfr2	9.507e-9	23.46	zinc finger RNA-binding protein-like [Source:NCBI ...	[more]
znf346	1.419e-6	29.73	zinc finger protein 346 [Source:NCBI gene;Acc:1030...	[more]
znf346	1.766e-6	29.73	zinc finger protein 346 [Source:NCBI gene;Acc:1030...	[more]
zfr	3.489e-6	32.32	zinc finger RNA binding protein [Source:NCBI gene;...	[more]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000003273.1	6.961e-6	27.18	pep scaffold:Pmarinus_7.0:GL476625:194967:224286:-...	[more]

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Zinc finger, C2H2-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
zfr	3.328e-6	29.41	zinc finger RNA binding protein [Source:NCBI gene;...	[more]
zfr	3.395e-6	29.41	zinc finger RNA binding protein [Source:NCBI gene;...	[more]

BLAST of Zinc finger, C2H2-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000067725.1	0.000e+0	96.80	SMESG000067725.1	[more]
SMESG000067725.1	0.000e+0	96.77	SMESG000067725.1	[more]
SMESG000074376.1	0.000e+0	73.33	SMESG000074376.1	[more]
SMESG000074376.1	7.352e-88	67.34	SMESG000074376.1	[more]
SMESG000067728.1	1.884e-39	30.96	SMESG000067728.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030966 ID=SMED30030966|Name=Zinc finger, C2H2-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1364bp
ATGAATAATATGTATGATAATGTTTCAAGTTACTGTTGTGTAGCTTGCAA
TATTTATTTCAATAATTTTGATGAACAAAAACAACATTGTTTCTTAAACC
ATTCTGGAAGTTATGATCATGAATCATTAAAATCAGCTCTGTATTCTCAA
TATAGATCACCATATGTGACTAACAAAAAAACTATTCCGGTGCAGTGCGA
TGTCTGCAATATAACCTGTTCATCCCAAACTACTTATGACTTTCATATCA
AAGGTAAAAAGCATACAAAAGCGTTGTCAAGAAAAGATTTATTTGAAAAT
GGAAAAACAGCAAGCAATGCTAAAGTTGAAGGAAACGACTGTATGGATCC
TGTTGAATATTCAGATCAACAAGGGCAAATATTATCTAAATCCAATTTGA
TGTGTGAAATTTGCGATGTCAATTGTTTAAGACCTGAACAATTAGAAAGA
CATTTGGAAGGATCGCGCCACCGTAAAAAGCTGAAACTGAATCGATATAT
TGAATTAAGGAATAACAAAGATCCATCTGTTTTCTGTGATATATGTGAAT
CATTCATGAATGAAGAGTCAATGAATATGCATCGAGCAAGTGGTAAGCAT
AAACGCAAAAGTTCTGCCGAAGTCAAAGATGAGCCTGCTGAGAAAAAGGC
GAGGAGCGCTGACATTCCCACGACTGTCGAGCACTGCGGATATTGCCACA
TGTCACTGAAGAATGCAAGCGATGCGATAGCTCACTACCAGACTCAGAAA
CACGCATTGAACATGACAAACCGCTCTAGGAACTTTGAATTATGGTGCGA
TGTCTGTCAGATATCATTCACCAATCAGAGCTTTCTCGATCTGCATTTGA
CAGGATTCAAGCATTTCGTGCGCGTGAACCGTGGCAACTCAGCTCCTGAA
GGCGCGTTTGGCGAGAGATTGATGAAGATGCGAGCGAAGCTTCAAAGTTT
GAAGCAGAGTAGGAAAGAGAAAAAGTCGAGTAACGATGAGAAATGCTCAA
TTGTGCCCAGTGAGCAACCGCAAAATGAGCCCTTGACAACAGCCAGTGAA
GATGCGGAAGGAACCTCTAATGGTTGCGATTAATTAATATTATTAGTAAT
CATCACAAGTCGCATTAAATGTTGTTTATATTTTCATTTATTTATCTATT
GTAATGTTTTATTATCAACTAAATGTTATGTTGTCGTATTAAGATGCGTT
TTCTGCTGCTAATGTTCCTTGAGTTTCCTTAGTGGTTGATTGACATCGAT
TATCGTATTTTCTAAAATGGAATAAAACGTATTGATTTTTGATGTGCAAT
TCAATTAATAGTTTCCAGAGCAGAATTGATTTTTAATGTAAAAATATATT
ATGCGAGATCGGAA

protein sequence of SMED30030966-orf-1

>SMED30030966-orf-1 ID=SMED30030966-orf-1|Name=SMED30030966-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=361bp
MNNMYDNVSSYCCVACNIYFNNFDEQKQHCFLNHSGSYDHESLKSALYSQ
YRSPYVTNKKTIPVQCDVCNITCSSQTTYDFHIKGKKHTKALSRKDLFEN
GKTASNAKVEGNDCMDPVEYSDQQGQILSKSNLMCEICDVNCLRPEQLER
HLEGSRHRKKLKLNRYIELRNNKDPSVFCDICESFMNEESMNMHRASGKH
KRKSSAEVKDEPAEKKARSADIPTTVEHCGYCHMSLKNASDAIAHYQTQK
HALNMTNRSRNFELWCDVCQISFTNQSFLDLHLTGFKHFVRVNRGNSAPE
GAFGERLMKMRAKLQSLKQSRKEKKSSNDEKCSIVPSEQPQNEPLTTASE
DAEGTSNGCD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR015880	Znf_C2H2-like
IPR003604	Matrin/U1-like-C_Znf_C2H2
IPR007087	Znf_C2H2

Vocabulary: **molecular function**
Term	Definition
GO:0008270	zinc ion binding
GO:0003676	nucleic acid binding
GO:0046872	metal ion binding

Main menu

Zinc finger, C2H2-like protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

blazegraph-runner