LITAF domain-containing protein

Overview
NameLITAF domain-containing protein
Smed IDSMED30030952
Length (bp)575
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of LITAF domain-containing protein (SMED30030952) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for LITAF domain-containing protein (SMED30030952) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030952

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30030952SMESG000020864.1 dd_Smed_v4_11813_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30030952SMESG000020864.1 dd_Smed_v4_11813_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30030952SMESG000020864.1 Contig50637newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30030952SMESG000020864.1 Contig50637uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30030952SMESG000020864.1 dd_Smed_v6_11813_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Category 3 cellSMED30030952SMESG000020864.1 dd_Smed_v4_11813_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Human
Match: LITAF (lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841])

HSP 1 Score: 56.9954 bits (136), Expect = 5.087e-10
Identity = 27/73 (36.99%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+CN+ I++ +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP C+ ++  +K
Sbjct:   89 DRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIA--GCCFIPFCVDALQDVDHYCPNCRALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Human
Match: LITAF (lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841])

HSP 1 Score: 56.9954 bits (136), Expect = 5.087e-10
Identity = 27/73 (36.99%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+CN+ I++ +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP C+ ++  +K
Sbjct:   89 DRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIA--GCCFIPFCVDALQDVDHYCPNCRALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Human
Match: LITAF (lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841])

HSP 1 Score: 56.9954 bits (136), Expect = 5.087e-10
Identity = 27/73 (36.99%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+CN+ I++ +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP C+ ++  +K
Sbjct:   89 DRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIA--GCCFIPFCVDALQDVDHYCPNCRALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Human
Match: LITAF (lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841])

HSP 1 Score: 56.9954 bits (136), Expect = 5.087e-10
Identity = 27/73 (36.99%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+CN+ I++ +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP C+ ++  +K
Sbjct:   89 DRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIA--GCCFIPFCVDALQDVDHYCPNCRALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Human
Match: LITAF (lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841])

HSP 1 Score: 56.9954 bits (136), Expect = 5.087e-10
Identity = 27/73 (36.99%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+CN+ I++ +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP C+ ++  +K
Sbjct:   89 DRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIA--GCCFIPFCVDALQDVDHYCPNCRALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Celegans
Match: Y87G2A.19 (pep chromosome:WBcel235:I:13508785:13512026:1 gene:WBGene00044260.1 transcript:Y87G2A.19.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y87G2A.19)

HSP 1 Score: 56.9954 bits (136), Expect = 8.039e-11
Identity = 28/77 (36.36%), Postives = 43/77 (55.84%), Query Frame = 1 
Query:  217 SSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGV----LLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            ++K YL D+P+++ CP C  +  T +    G FT +S  ++ +    +LP      PFC+E FKDA H CP C+  I
Sbjct:   24 NAKKYLSDRPQLLDCPRCKVHGETELRFVNGFFTYVSFFIILIFGFAILPLFFLWVPFCVETFKDAEHYCPSCRAWI 100
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Celegans
Match: Y87G2A.19 (pep chromosome:WBcel235:I:13508814:13512026:1 gene:WBGene00044260.1 transcript:Y87G2A.19.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y87G2A.19)

HSP 1 Score: 56.9954 bits (136), Expect = 8.039e-11
Identity = 28/77 (36.36%), Postives = 43/77 (55.84%), Query Frame = 1 
Query:  217 SSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGV----LLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            ++K YL D+P+++ CP C  +  T +    G FT +S  ++ +    +LP      PFC+E FKDA H CP C+  I
Sbjct:   24 NAKKYLSDRPQLLDCPRCKVHGETELRFVNGFFTYVSFFIILIFGFAILPLFFLWVPFCVETFKDAEHYCPSCRAWI 100
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Celegans
Match: nmr-1 (NMDA class glutamate Receptor; NMDA-type ionotropic glutamate receptor NMR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGQ9])

HSP 1 Score: 55.4546 bits (132), Expect = 4.109e-9
Identity = 27/90 (30.00%), Postives = 42/90 (46.67%), Query Frame = 1 
Query:  178 KNQIKILDRDQVDSSKSY----LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            + QI+ L   +VD    +     KDKP ++ C  C   + + V  + G F  LSC +  +L  + C   P  L  F D +H CP C  ++
Sbjct:  923 RRQIRGLPTSKVDPYCFWPDLDFKDKPLVLFCSRCRNIVESDVHRETGLFAFLSCFLFAILFLWPCSPLPCFLSSFSDFVHICPLCSHIM 1012
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Celegans
Match: nmr-1 (NMDA class glutamate Receptor; NMDA-type ionotropic glutamate receptor NMR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGQ9])

HSP 1 Score: 55.4546 bits (132), Expect = 4.109e-9
Identity = 27/90 (30.00%), Postives = 42/90 (46.67%), Query Frame = 1 
Query:  178 KNQIKILDRDQVDSSKSY----LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            + QI+ L   +VD    +     KDKP ++ C  C   + + V  + G F  LSC +  +L  + C   P  L  F D +H CP C  ++
Sbjct:  923 RRQIRGLPTSKVDPYCFWPDLDFKDKPLVLFCSRCRNIVESDVHRETGLFAFLSCFLFAILFLWPCSPLPCFLSSFSDFVHICPLCSHIM 1012
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Celegans
Match: Y37D8A.6 (pep chromosome:WBcel235:III:12856833:12857911:-1 gene:WBGene00012548.1 transcript:Y37D8A.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y37D8A.6)

HSP 1 Score: 50.0618 bits (118), Expect = 4.655e-8
Identity = 28/67 (41.79%), Postives = 36/67 (53.73%), Query Frame = 1 
Query:  241 KPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLG--VLLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            +P    CP CN  + T V   +G F   + L LG  V  P  CC   FCL+GFKD+ HSCP C  ++
Sbjct:   65 EPYTEFCPRCNTNVCTRVERTMG-FCSWTMLFLGLFVFFPLLCC---FCLDGFKDSRHSCPNCGTIL 127
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-157c3.4 (si:ch211-157c3.4 [Source:ZFIN;Acc:ZDB-GENE-030131-8454])

HSP 1 Score: 66.6254 bits (161), Expect = 6.469e-14
Identity = 36/95 (37.89%), Postives = 59/95 (62.11%), Query Frame = 1 
Query:  163 SDRVIKNQIKILDRDQVDSSKSY-LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            S R +++Q     R++  S +SY L  KP +  C +C + ++T V +K+G +  L C+++   G +L  GCCL PF ++ FKDA HSCP+C K++
Sbjct:   49 SSRPVQSQ-STEARNKYVSYESYELGRKPAMATCTSCQQQVLTNVTYKVGVYAWLMCILIFFCGFVL--GCCLIPFFMKFFKDAYHSCPRCNKIL 140
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-157c3.4 (si:ch211-157c3.4 [Source:ZFIN;Acc:ZDB-GENE-030131-8454])

HSP 1 Score: 66.6254 bits (161), Expect = 6.469e-14
Identity = 36/95 (37.89%), Postives = 59/95 (62.11%), Query Frame = 1 
Query:  163 SDRVIKNQIKILDRDQVDSSKSY-LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            S R +++Q     R++  S +SY L  KP +  C +C + ++T V +K+G +  L C+++   G +L  GCCL PF ++ FKDA HSCP+C K++
Sbjct:   49 SSRPVQSQ-STEARNKYVSYESYELGRKPAMATCTSCQQQVLTNVTYKVGVYAWLMCILIFFCGFVL--GCCLIPFFMKFFKDAYHSCPRCNKIL 140
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-157c3.4 (si:ch211-157c3.4 [Source:ZFIN;Acc:ZDB-GENE-030131-8454])

HSP 1 Score: 66.6254 bits (161), Expect = 6.469e-14
Identity = 36/95 (37.89%), Postives = 59/95 (62.11%), Query Frame = 1 
Query:  163 SDRVIKNQIKILDRDQVDSSKSY-LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            S R +++Q     R++  S +SY L  KP +  C +C + ++T V +K+G +  L C+++   G +L  GCCL PF ++ FKDA HSCP+C K++
Sbjct:   49 SSRPVQSQ-STEARNKYVSYESYELGRKPAMATCTSCQQQVLTNVTYKVGVYAWLMCILIFFCGFVL--GCCLIPFFMKFFKDAYHSCPRCNKIL 140
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-202h22.8 (si:ch211-202h22.8 [Source:ZFIN;Acc:ZDB-GENE-090313-78])

HSP 1 Score: 65.0846 bits (157), Expect = 2.162e-13
Identity = 34/80 (42.50%), Postives = 43/80 (53.75%), Query Frame = 1 
Query:  208 QVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            QV      L D P    CP+C + I+T   +  G  T L C  LG+LL + CCL PFC+   KD  H CP CK V+F +K
Sbjct:   56 QVVMMPPSLSDVPGQTKCPHCQQQIITETRYVNGLLTWLICGGLGILLIWPCCLIPFCVSACKDVEHRCPNCKHVVFLYK 135
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-202h22.8 (si:ch211-202h22.8 [Source:ZFIN;Acc:ZDB-GENE-090313-78])

HSP 1 Score: 65.0846 bits (157), Expect = 2.162e-13
Identity = 34/80 (42.50%), Postives = 43/80 (53.75%), Query Frame = 1 
Query:  208 QVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            QV      L D P    CP+C + I+T   +  G  T L C  LG+LL + CCL PFC+   KD  H CP CK V+F +K
Sbjct:   56 QVVMMPPSLSDVPGQTKCPHCQQQIITETRYVNGLLTWLICGGLGILLIWPCCLIPFCVSACKDVEHRCPNCKHVVFLYK 135
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000031517.1 (LITAF domain containing [Source:NCBI gene;Acc:100498168])

HSP 1 Score: 55.0694 bits (131), Expect = 1.958e-9
Identity = 28/78 (35.90%), Postives = 44/78 (56.41%), Query Frame = 1 
Query:  226 SYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGC----CLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            S  +D P    CP+C + I+T + + IG    L+ L+ G+L  +GC    CL PFC++  KD  H CP C   ++++K
Sbjct:   65 STFQDTPASTTCPSCRQNIITNIHYNIGL---LTWLLFGILFIFGCWLGCCLIPFCVDSCKDVDHYCPNCNHHLYKYK 139
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Xenopus
Match: aff2 (AF4/FMR2 family member 2 [Source:Xenbase;Acc:XB-GENE-952102])

HSP 1 Score: 52.7582 bits (125), Expect = 2.615e-8
Identity = 29/77 (37.66%), Postives = 41/77 (53.25%), Query Frame = 1 
Query:  232 LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            L D+P  M C +CN  I T + +  G    LSC    +LG +   GCCL PFC++  KD  H CP C  ++  +K +
Sbjct:  114 LYDRPVQMCCRSCNSMITTRLEYSSGALAWLSCGGLCLLGCIG--GCCLIPFCIDSLKDVDHYCPNCHALLGSYKRI 188
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Xenopus
Match: pfkfb4 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:Xenbase;Acc:XB-GENE-1001570])

HSP 1 Score: 51.9878 bits (123), Expect = 3.682e-8
Identity = 27/77 (35.06%), Postives = 42/77 (54.55%), Query Frame = 1 
Query:  226 SYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            S  +D P    CPNCN+ I+T + + +G F+ +   V    G  L  GCC+ PF ++  KD  H CP C  ++ ++K
Sbjct:   96 SSFQDTPVTATCPNCNQRIITRLQYSVGLFSWILFAVFMFFGCWL--GCCIIPFVMDRCKDVDHYCPSCNYLLHKYK 170
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Xenopus
Match: pfkfb4 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:Xenbase;Acc:XB-GENE-1001570])

HSP 1 Score: 51.9878 bits (123), Expect = 4.281e-8
Identity = 27/77 (35.06%), Postives = 42/77 (54.55%), Query Frame = 1 
Query:  226 SYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            S  +D P    CPNCN+ I+T + + +G F+ +   V    G  L  GCC+ PF ++  KD  H CP C  ++ ++K
Sbjct:   96 SSFQDTPVTATCPNCNQRIITRLQYSVGLFSWILFAVFMFFGCWL--GCCIIPFVMDRCKDVDHYCPSCNYLLHKYK 170
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Xenopus
Match: pfkfb4 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:Xenbase;Acc:XB-GENE-1001570])

HSP 1 Score: 51.9878 bits (123), Expect = 4.456e-8
Identity = 27/77 (35.06%), Postives = 42/77 (54.55%), Query Frame = 1 
Query:  226 SYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            S  +D P    CPNCN+ I+T + + +G F+ +   V    G  L  GCC+ PF ++  KD  H CP C  ++ ++K
Sbjct:   96 SSFQDTPVTATCPNCNQRIITRLQYSVGLFSWILFAVFMFFGCWL--GCCIIPFVMDRCKDVDHYCPSCNYLLHKYK 170
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Mouse
Match: Litaf (LPS-induced TN factor [Source:MGI Symbol;Acc:MGI:1929512])

HSP 1 Score: 57.3806 bits (137), Expect = 3.026e-10
Identity = 28/73 (38.36%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+C++ I+T +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP CK ++  +K
Sbjct:   89 DRPVQMCCPSCSKMIVTQLSYNAGALTWLSCGSLCLLGCVA--GCCFIPFCVDALQDVDHYCPNCKALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Mouse
Match: Litaf (LPS-induced TN factor [Source:MGI Symbol;Acc:MGI:1929512])

HSP 1 Score: 57.3806 bits (137), Expect = 3.026e-10
Identity = 28/73 (38.36%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+C++ I+T +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP CK ++  +K
Sbjct:   89 DRPVQMCCPSCSKMIVTQLSYNAGALTWLSCGSLCLLGCVA--GCCFIPFCVDALQDVDHYCPNCKALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Mouse
Match: Gm5767 (predicted gene 5767 [Source:MGI Symbol;Acc:MGI:3643507])

HSP 1 Score: 49.6766 bits (117), Expect = 4.060e-8
Identity = 28/68 (41.18%), Postives = 34/68 (50.00%), Query Frame = 1 
Query:  259 CPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKC-KKVIFEHKL 450
            CP C   IMT   +  G  T L C    V G  L  GCCL PFC+    D  HSCP C  ++ + H+L
Sbjct:   11 CPYCGNRIMTVTTYTPGLLTWLLCSGLFVFGCFL--GCCLIPFCIRSTMDVTHSCPMCHHQIYYFHRL 76
[Close]
BLAST of LITAF domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6GMG8|LITAF_DANRE (Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog OS=Danio rerio OX=7955 GN=litaf PE=2 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 1.472e-10
Identity = 30/73 (41.10%), Postives = 39/73 (53.42%), Query Frame = 1 
Query:  232 LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLL-PYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
              + P   HCP C++ ++T + +  G    LSC  L V    YGCCL PFC+E  KD  H CP C  V+  HK
Sbjct:   89 FGNVPVQAHCPVCSQSVITRLEYSSGPLVWLSCAGLAVFGCIYGCCLIPFCIEDLKDVTHHCPNCSSVLGVHK 161
[Close]
BLAST of LITAF domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8QGW7|LITAF_CHICK (Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog OS=Gallus gallus OX=9031 GN=LITAF PE=2 SV=1)

HSP 1 Score: 59.6918 bits (143), Expect = 2.023e-10
Identity = 30/73 (41.10%), Postives = 43/73 (58.90%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+CN+ I+T + ++ G  T LSC    +LG +   GCCL PFC++  KD  H CP C   +  +K
Sbjct:   76 DRPVQMSCPSCNQMIVTRLCYESGALTWLSCGGLFLLGCIA--GCCLIPFCVDALKDVEHFCPNCNAHVGSYK 146
[Close]
BLAST of LITAF domain-containing protein vs. UniProt/SwissProt
Match: sp|P0C0T0|LITAF_RAT (Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog OS=Rattus norvegicus OX=10116 GN=Litaf PE=2 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 4.984e-10
Identity = 29/73 (39.73%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+CN+ I+T +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP CK ++  +K
Sbjct:   89 DRPIQMCCPSCNKMIVTQLSYNAGALTWLSCGSLCLLGCVA--GCCFIPFCVDALQDVDHYCPNCKALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6GZQ0|075L_FRG3G (Uncharacterized protein 075L OS=Frog virus 3 (isolate Goorha) OX=654924 GN=FV3-075L PE=4 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 7.214e-10
Identity = 29/83 (34.94%), Postives = 46/83 (55.42%), Query Frame = 1 
Query:  205 DQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            D+  +    L+D P  + CP+C+  I TAV H +G+ + + C  +  L    CC  PF     KD  H+CPKCK+ +F +K++
Sbjct:    3 DKFTTLPCELEDYPGSITCPHCSAQITTAVDHVVGKMSWVVCTAI-TLACLPCCCIPFLCNSTKDVRHTCPKCKQAVFVYKIL 84
[Close]
BLAST of LITAF domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9JLJ0|LITAF_MOUSE (Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog OS=Mus musculus OX=10090 GN=Litaf PE=1 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 2.117e-9
Identity = 28/73 (38.36%), Postives = 44/73 (60.27%), Query Frame = 1 
Query:  238 DKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            D+P  M CP+C++ I+T +++  G  T LSC    +LG +   GCC  PFC++  +D  H CP CK ++  +K
Sbjct:   89 DRPVQMCCPSCSKMIVTQLSYNAGALTWLSCGSLCLLGCVA--GCCFIPFCVDALQDVDHYCPNCKALLGTYK 159
[Close]
BLAST of LITAF domain-containing protein vs. TrEMBL
Match: A0A3P8URZ5 (LITAF domain-containing protein OS=Cynoglossus semilaevis OX=244447 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.707e-12
Identity = 36/92 (39.13%), Postives = 52/92 (56.52%), Query Frame = 1 
Query:  172 VIKNQIKILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            V+  Q +   R +  S +  L   P +  CP+C   + + V +K+G    L CLV  VLL +GCCL PF ++ FKDA HSCP C +V+  H+
Sbjct:   54 VVSVQPQTTPRTKFVSYEVELYRSPALTRCPSCQTRVTSQVNYKVGTHAWLMCLVF-VLLVFGCCLIPFFVDHFKDAYHSCPLCHRVLHVHR 144
[Close]
BLAST of LITAF domain-containing protein vs. TrEMBL
Match: A0A3P9A8L6 (LITAF domain-containing protein OS=Esox lucius OX=8010 PE=4 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 4.190e-12
Identity = 31/65 (47.69%), Postives = 40/65 (61.54%), Query Frame = 1 
Query:  253 MHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            M CP C   ++T   H+ G+FT   C +LG+LL + CCL PFC+   KD  H CP CK+VI  HK
Sbjct:   89 MTCPECQVQVLTNTTHQNGKFTWFLCGILGILLIWPCCLIPFCVASCKDVAHQCPNCKRVIHVHK 153
[Close]
BLAST of LITAF domain-containing protein vs. TrEMBL
Match: A0A5N5MGW0 (Uncharacterized protein OS=Pangasianodon hypophthalmus OX=310915 GN=PHYPO_G00048380 PE=4 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 4.362e-12
Identity = 35/86 (40.70%), Postives = 53/86 (61.63%), Query Frame = 1 
Query:  199 DRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            DR++  S +S L   P ++ C +C E ++T V +K+G +  L CL+    G ++  GCCL PFCL+ FKD  HSCPKC +++   K
Sbjct:   57 DRNKFVSYESELGRSPGMVTCTSCREQVLTQVTYKVGMYAWLMCLLFILCGFVI--GCCLLPFCLKFFKDVYHSCPKCHRILHVEK 140
[Close]
BLAST of LITAF domain-containing protein vs. TrEMBL
Match: A0A397GTB0 (LITAF domain-containing protein OS=Diversispora epigaea OX=1348612 GN=Glove_457g61 PE=4 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 9.404e-12
Identity = 42/123 (34.15%), Postives = 68/123 (55.28%), Query Frame = 1 
Query:  103 YSEKPTLIFEH--VQKGLQVSKSDR-VIKNQIKILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGR---FTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            YS  P LI+    +++ + + K    +   Q  +L +D        L+ +P I  CP+CN+ ++++  +K G     T L+ LVLG L  +GCCL PFC+   KD IHSCPKC K++ ++  +
Sbjct:   46 YSATPNLIYSPPPLEQNVPIPKPLPCIFVEQSPVLLQD--------LRTEPCITSCPHCNQIVLSSTKYKSGSATYLTSLTLLVLG-LTSWGCCLIPFCVNNLKDCIHSCPKCGKIMAKYSRI 159
[Close]
BLAST of LITAF domain-containing protein vs. TrEMBL
Match: A0A1S3QQD1 (lipopolysaccharide-induced tumor necrosis factor-alpha factor-like OS=Salmo salar OX=8030 GN=LOC106595417 PE=4 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 1.118e-11
Identity = 34/82 (41.46%), Postives = 48/82 (58.54%), Query Frame = 1 
Query:  211 VDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            V   ++ L D P ++ CP+C   +M+ V H  G F+   CLV    G+ L  GCCL PF L+ FKDA H+CP+C  V+  H+
Sbjct:   36 VQHYETELGDSPGLIRCPSCQNQVMSDVTHHAGTFSWTMCLVFILCGLFL--GCCLIPFFLKSFKDAYHACPRCHMVLHVHR 115
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-157c3.4 (lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [Source:NCBI gene;Acc:103024010])

HSP 1 Score: 62.7734 bits (151), Expect = 1.666e-12
Identity = 33/106 (31.13%), Postives = 56/106 (52.83%), Query Frame = 1 
Query:  139 QKGLQVSKSDRVIKNQIKILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
              G+Q + +D           +++  S  S L   P    C +C E ++T V +K+G F  L C++    G+++  GCCL PF ++ FKDA H+CP+C +++   K
Sbjct:   45 SSGVQATSADNA---------KNKYVSYDSELGRSPGTTTCTSCREQVLTNVTYKVGAFAWLMCILFILCGLVI--GCCLIPFFVKYFKDAYHTCPRCNRILHVEK 139
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Cavefish
Match: litaf (lipopolysaccharide-induced TNF factor [Source:NCBI gene;Acc:431731])

HSP 1 Score: 58.9214 bits (141), Expect = 5.485e-11
Identity = 27/71 (38.03%), Postives = 39/71 (54.93%), Query Frame = 1 
Query:  232 LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSC---LVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
                P  +HCPNC + ++T + +  G  T L+C    + G +  YGCCL PFC++  KD  H CP C  V+
Sbjct:   78 FGHTPVQVHCPNCAQTVVTRLDYSSGTMTWLTCAGLFIFGCI--YGCCLIPFCVDSLKDVTHHCPNCSSVL 146
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Cavefish
Match: cdip1 (cell death inducing p53 target 1 [Source:NCBI gene;Acc:103033134])

HSP 1 Score: 51.9878 bits (123), Expect = 4.444e-8
Identity = 26/68 (38.24%), Postives = 39/68 (57.35%), Query Frame = 1 
Query:  259 CPNCNEYIMTAVAHKIGRFT---CLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            CP+C + I+T ++H +G      CL C  +G  L  GCCL P  ++  KD  H+CP CK  I+ +K +
Sbjct:  146 CPHCQQAIITRISHDVGLMNTLFCLFCFFVGCDL--GCCLIPCLIDDLKDVTHTCPNCKGYIYTYKRI 211
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000041239.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:195968:202131:-1 gene:ENSAMXG00000040302.1 transcript:ENSAMXT00000041239.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 5.750e-8
Identity = 28/72 (38.89%), Postives = 37/72 (51.39%), Query Frame = 1 
Query:  232 LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
              D P  + CP C    +T V +  G  T L C   G+L   GCCL PFC++  +DA H C  CK V+  +K
Sbjct:   50 FTDSPVQVTCPTCRHTAVTQVQYTPGLLTYLFCG--GLLCFLGCCLIPFCVDRLRDAKHVCSNCKAVLGVYK 119
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Nematostella
Match: EDO33373 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSF9])

HSP 1 Score: 57.7658 bits (138), Expect = 2.077e-11
Identity = 25/67 (37.31%), Postives = 38/67 (56.72%), Query Frame = 1 
Query:  232 LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVL-LPYGCCLAPFCLEGFKDAIHSCPKCKK 429
              + P  M+CP C+  I+TA  +  G  T L+C  L ++    GCC  PFC++  KD +H+CP C+ 
Sbjct:   29 FYETPVSMNCPTCHATIVTATDYVTGTLTWLACFGLCIIGCDLGCCFIPFCVDSMKDVVHTCPNCRS 95
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Nematostella
Match: EDO37779 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW4])

HSP 1 Score: 57.7658 bits (138), Expect = 9.830e-11
Identity = 27/72 (37.50%), Postives = 43/72 (59.72%), Query Frame = 1 
Query:  235 KDKPEIMHCPNCNEYIMTAVAHKIGRFT-CLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            +D+     C +C  ++MT V  +IGR T  +S LV  +    GCCL PF ++G +D IHSCP C+  + +++
Sbjct:   83 RDESVYTFCGSCMNHMMTVVRFRIGRMTVAVSALVFMLGCVAGCCLVPFIIKGLRDVIHSCPNCQITLGKYR 154
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Nematostella
Match: EDO42963 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S062])

HSP 1 Score: 55.4546 bits (132), Expect = 1.332e-10
Identity = 31/90 (34.44%), Postives = 45/90 (50.00%), Query Frame = 1 
Query:  160 KSDRVIKNQIKILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKK 429
            +   VI+ Q  ++    V   +S     P  M CP C   I+TA ++  G    L CLV+     + CC  PF L+G KD +HSCP C++
Sbjct:   14 QHTTVIQQQPTVVVTGGVSFGES-----PTSMVCPYCQATIVTATSYVPGTCAWLICLVIFCFF-WPCCFLPFVLDGCKDVVHSCPNCQR 97
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Nematostella
Match: EDO37753 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SES1])

HSP 1 Score: 53.1434 bits (126), Expect = 4.817e-10
Identity = 29/69 (42.03%), Postives = 40/69 (57.97%), Query Frame = 1 
Query:  253 MHCPNCNEYIMTAVAHKIGRFTCL----SCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            M C  C  +I+TA  ++ G  T L     CL+ G L   GCCL PFCL+G KD IH+CP C+  +  ++
Sbjct:    1 MVCSFCQTHIVTATTYRYGALTWLLSGGICLLGGWL---GCCLIPFCLDGCKDVIHTCPNCQAQLGVYR 66
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Medaka
Match: si:ch211-202h22.9 (si:ch211-202h22.9 [Source:ZFIN;Acc:ZDB-GENE-030131-1143])

HSP 1 Score: 63.5438 bits (153), Expect = 2.178e-12
Identity = 30/75 (40.00%), Postives = 42/75 (56.00%), Query Frame = 1 
Query:  223 KSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            + +  D P  M CP+C   ++T   HK+G  T L   VLG++  + CCL PFC+   KD  HSCP C  V+  H+
Sbjct:  112 QPHPTDCPGQMLCPHCQNTVVTKTEHKVGMQTWLIFGVLGIIGCWPCCLIPFCVNSCKDVQHSCPSCNNVLHVHR 186
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000033265.1 (pep primary_assembly:ASM223467v1:8:8133676:8134078:-1 gene:ENSORLG00000030072.1 transcript:ENSORLT00000033265.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 8.651e-11
Identity = 31/86 (36.05%), Postives = 42/86 (48.84%), Query Frame = 1 
Query:  193 ILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVL-LPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            ILD D+       L  +P    CP C ++++T  +  I   T L C++  +L    GCCL PFC   FK   H CPKC+  I   K
Sbjct:   22 ILDTDK-------LPPEPSRTQCPQCQQFVVTETSTSISSVTWLVCVMTALLGCVAGCCLIPFCSNKFKSITHRCPKCRTSIATLK 100
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000040558.1 (cell death-inducing p53-target protein 1-like [Source:NCBI gene;Acc:101164847])

HSP 1 Score: 56.9954 bits (136), Expect = 7.471e-10
Identity = 29/69 (42.03%), Postives = 37/69 (53.62%), Query Frame = 1 
Query:  232 LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLL-PYGCCLAPFCLEGFKDAIHSCPKCKKVI 435
            L  KP    CP+C   I+T    K+G  +CL C V   L    GCCL PF    FK+ +HSCP+C+  I
Sbjct:  166 LGHKPATTKCPSCQAVIVTQTRFKVGLSSCLVCFVCSTLGCVAGCCLIPFFTNRFKNVLHSCPRCQTHI 234
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000037533.1 (pep primary_assembly:ASM223467v1:1:23682164:23683902:-1 gene:ENSORLG00000026577.1 transcript:ENSORLT00000037533.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 1.357e-9
Identity = 31/75 (41.33%), Postives = 42/75 (56.00%), Query Frame = 1 
Query:  232 LKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL---GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            L   P  + CP C+  +++ V H  G  T L C  L   G +L  GCCL PFC++  KDA HSCP CK ++  +K
Sbjct:   32 LGANPVQIACPKCHRTVLSKVDHSAGLLTYLLCGGLFFCGFVL--GCCLIPFCVDRVKDAKHSCPSCKTILGVYK 104
[Close]
BLAST of LITAF domain-containing protein vs. Ensembl Medaka
Match: cdip1 (cell death inducing p53 target 1 [Source:NCBI gene;Acc:101173632])

HSP 1 Score: 51.2174 bits (121), Expect = 6.376e-8
Identity = 26/68 (38.24%), Postives = 39/68 (57.35%), Query Frame = 1 
Query:  259 CPNCNEYIMTAVAHKIGRFT---CLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            CP+C + I+T ++H +G      CL C  +G  L  GCCL P  ++  KD  H+CP CK  I+ +K +
Sbjct:  139 CPHCQQAIVTRISHDVGLMNTLFCLFCFFVGCDL--GCCLIPCLIDDLKDVTHTCPYCKGYIYTYKRI 204
[Close]
BLAST of LITAF domain-containing protein vs. Planmine SMEST
Match: SMESG000020864.1 (SMESG000020864.1)

HSP 1 Score: 279.641 bits (714), Expect = 8.627e-98
Identity = 137/138 (99.28%), Postives = 137/138 (99.28%), Query Frame = 1 
Query:   40 MVVEKFRNPDKIQPSIFYIECYSEKPTLIFEHVQKGLQVSKSDRVIKNQIKILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            MVVEKFRNPDKIQPSIFYIECYSEKPTLIFEHVQK LQVSKSDRVIKNQIKILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV
Sbjct:    1 MVVEKFRNPDKIQPSIFYIECYSEKPTLIFEHVQKDLQVSKSDRVIKNQIKILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 138
[Close]
BLAST of LITAF domain-containing protein vs. Planmine SMEST
Match: SMESG000033033.1 (SMESG000033033.1)

HSP 1 Score: 63.1586 bits (152), Expect = 2.622e-13
Identity = 31/63 (49.21%), Postives = 38/63 (60.32%), Query Frame = 1 
Query:  259 CPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHK 447
            CP C E I+T V  K+G  T L C  +G+  P GCCL PFCL   KDA H CPKC + +  +K
Sbjct:   29 CPKCLEEILTVVKFKVGCQTWLFCFGIGIFCPLGCCLIPFCLRECKDAHHFCPKCDRYLGRYK 91
[Close]
BLAST of LITAF domain-containing protein vs. Planmine SMEST
Match: SMESG000020865.1 (SMESG000020865.1)

HSP 1 Score: 60.4622 bits (145), Expect = 7.478e-12
Identity = 25/63 (39.68%), Postives = 37/63 (58.73%), Query Frame = 1 
Query:  253 MHCPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFE 441
            + C  C   +  A+++K G FT L C ++ +  P GCCL PFC+ GFKD  + CP C   ++E
Sbjct:   73 VRCDKCENEVFPAISYKSGGFTWLMCFIIFLFAPIGCCLIPFCINGFKDEKYKCPICDHKLYE 135
[Close]
BLAST of LITAF domain-containing protein vs. Planmine SMEST
Match: SMESG000079265.1 (SMESG000079265.1)

HSP 1 Score: 48.521 bits (114), Expect = 5.487e-8
Identity = 28/74 (37.84%), Postives = 41/74 (55.41%), Query Frame = 1 
Query:  244 PEIMHCPNCNEYIMTAVAHKIGRFTCL----SCLVLGVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            P  M CP+CN  I+T V +  G  T L    +C +  V    GCCL PF ++ FKD  H CP+C  ++ E++ +
Sbjct:    2 PVSMVCPHCNSTIVTTVRYDNGTLTFLLAFITCFIGCVC---GCCLIPFFVKQFKDVKHYCPRCNALLGEYRRI 72
[Close]
BLAST of LITAF domain-containing protein vs. Planmine SMEST
Match: SMESG000020853.1 (SMESG000020853.1)

HSP 1 Score: 48.9062 bits (115), Expect = 1.388e-7
Identity = 28/66 (42.42%), Postives = 38/66 (57.58%), Query Frame = 1 
Query:  259 CPNCNEYIMTAVAHKIGRFTCLSCLVLGVLLPY-GCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV 453
            CP+C   I+T + +  G  T L C  L +L  + GCCL PFC++  KD IH CP C   + EH+ V
Sbjct:   63 CPHCQAQIVTGIRYDNGLLTWLLCGGLALLGCWLGCCLIPFCVDDCKDVIHVCPSCNMKVGEHRRV 128
The following BLAST results are available for this feature:
BLAST of LITAF domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LITAF5.087e-1036.99lipopolysaccharide induced TNF factor [Source:HGNC... [more]
LITAF5.087e-1036.99lipopolysaccharide induced TNF factor [Source:HGNC... [more]
LITAF5.087e-1036.99lipopolysaccharide induced TNF factor [Source:HGNC... [more]
LITAF5.087e-1036.99lipopolysaccharide induced TNF factor [Source:HGNC... [more]
LITAF5.087e-1036.99lipopolysaccharide induced TNF factor [Source:HGNC... [more]
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BLAST of LITAF domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Y87G2A.198.039e-1136.36pep chromosome:WBcel235:I:13508785:13512026:1 gene... [more]
Y87G2A.198.039e-1136.36pep chromosome:WBcel235:I:13508814:13512026:1 gene... [more]
nmr-14.109e-930.00NMDA class glutamate Receptor; NMDA-type ionotropi... [more]
nmr-14.109e-930.00NMDA class glutamate Receptor; NMDA-type ionotropi... [more]
Y37D8A.64.655e-841.79pep chromosome:WBcel235:III:12856833:12857911:-1 g... [more]
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BLAST of LITAF domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of LITAF domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-157c3.46.469e-1437.89si:ch211-157c3.4 [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
si:ch211-157c3.46.469e-1437.89si:ch211-157c3.4 [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
si:ch211-157c3.46.469e-1437.89si:ch211-157c3.4 [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
si:ch211-202h22.82.162e-1342.50si:ch211-202h22.8 [Source:ZFIN;Acc:ZDB-GENE-090313... [more]
si:ch211-202h22.82.162e-1342.50si:ch211-202h22.8 [Source:ZFIN;Acc:ZDB-GENE-090313... [more]
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BLAST of LITAF domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000031517.11.958e-935.90LITAF domain containing [Source:NCBI gene;Acc:1004... [more]
aff22.615e-837.66AF4/FMR2 family member 2 [Source:Xenbase;Acc:XB-GE... [more]
pfkfb43.682e-835.066-phosphofructo-2-kinase/fructose-2,6-biphosphatas... [more]
pfkfb44.281e-835.066-phosphofructo-2-kinase/fructose-2,6-biphosphatas... [more]
pfkfb44.456e-835.066-phosphofructo-2-kinase/fructose-2,6-biphosphatas... [more]
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BLAST of LITAF domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Litaf3.026e-1038.36LPS-induced TN factor [Source:MGI Symbol;Acc:MGI:1... [more]
Litaf3.026e-1038.36LPS-induced TN factor [Source:MGI Symbol;Acc:MGI:1... [more]
Gm57674.060e-841.18predicted gene 5767 [Source:MGI Symbol;Acc:MGI:364... [more]
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BLAST of LITAF domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6GMG8|LITAF_DANRE1.472e-1041.10Lipopolysaccharide-induced tumor necrosis factor-a... [more]
sp|Q8QGW7|LITAF_CHICK2.023e-1041.10Lipopolysaccharide-induced tumor necrosis factor-a... [more]
sp|P0C0T0|LITAF_RAT4.984e-1039.73Lipopolysaccharide-induced tumor necrosis factor-a... [more]
sp|Q6GZQ0|075L_FRG3G7.214e-1034.94Uncharacterized protein 075L OS=Frog virus 3 (isol... [more]
sp|Q9JLJ0|LITAF_MOUSE2.117e-938.36Lipopolysaccharide-induced tumor necrosis factor-a... [more]
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BLAST of LITAF domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3P8URZ51.707e-1239.13LITAF domain-containing protein OS=Cynoglossus sem... [more]
A0A3P9A8L64.190e-1247.69LITAF domain-containing protein OS=Esox lucius OX=... [more]
A0A5N5MGW04.362e-1240.70Uncharacterized protein OS=Pangasianodon hypophtha... [more]
A0A397GTB09.404e-1234.15LITAF domain-containing protein OS=Diversispora ep... [more]
A0A1S3QQD11.118e-1141.46lipopolysaccharide-induced tumor necrosis factor-a... [more]
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BLAST of LITAF domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
si:ch211-157c3.41.666e-1231.13lipopolysaccharide-induced tumor necrosis factor-a... [more]
litaf5.485e-1138.03lipopolysaccharide-induced TNF factor [Source:NCBI... [more]
cdip14.444e-838.24cell death inducing p53 target 1 [Source:NCBI gene... [more]
ENSAMXT00000041239.15.750e-838.89pep primary_assembly:Astyanax_mexicanus-2.0:12:195... [more]
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BLAST of LITAF domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of LITAF domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of LITAF domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO333732.077e-1137.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO377799.830e-1137.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO429631.332e-1034.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO377534.817e-1042.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of LITAF domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-202h22.92.178e-1240.00si:ch211-202h22.9 [Source:ZFIN;Acc:ZDB-GENE-030131... [more]
ENSORLT00000033265.18.651e-1136.05pep primary_assembly:ASM223467v1:8:8133676:8134078... [more]
ENSORLT00000040558.17.471e-1042.03cell death-inducing p53-target protein 1-like [Sou... [more]
ENSORLT00000037533.11.357e-941.33pep primary_assembly:ASM223467v1:1:23682164:236839... [more]
cdip16.376e-838.24cell death inducing p53 target 1 [Source:NCBI gene... [more]
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BLAST of LITAF domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000020864.18.627e-9899.28SMESG000020864.1[more]
SMESG000033033.12.622e-1349.21SMESG000033033.1[more]
SMESG000020865.17.478e-1239.68SMESG000020865.1[more]
SMESG000079265.15.487e-837.84SMESG000079265.1[more]
SMESG000020853.11.388e-742.42SMESG000020853.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030952 ID=SMED30030952|Name=LITAF domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=575bp
ATTGTTTTAAATTTTATAAATTTAATTTCACTATAATAAATGGTGGTGGA
GAAATTTCGAAATCCAGATAAAATACAACCTTCAATATTCTATATAGAAT
GCTATTCAGAAAAACCCACGTTAATATTTGAACATGTTCAAAAAGGTTTA
CAAGTCAGTAAATCAGATAGAGTCATAAAGAACCAGATTAAAATTCTTGA
TCGGGATCAAGTAGATTCTTCCAAGTCTTATCTGAAAGATAAACCTGAAA
TTATGCATTGTCCCAATTGCAATGAATATATTATGACTGCAGTGGCCCAC
AAAATTGGGCGGTTTACTTGTCTGTCGTGCTTGGTGTTAGGAGTTCTTTT
ACCTTATGGTTGCTGCTTGGCACCTTTTTGTTTGGAAGGATTCAAAGATG
CAATTCATTCCTGTCCAAAATGCAAGAAAGTCATTTTTGAACACAAATTA
GTCTAAGCATTTTGAAGAATTCGTTCCAATTGAAATTCCAATTTTCATAT
TTTAACAATACAATTGTTTGTTGATATGTAAAAATGAACAAATTCTTTGA
TATAAATTTATAAACTTCTTTAAAA
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protein sequence of SMED30030952-orf-1

>SMED30030952-orf-1 ID=SMED30030952-orf-1|Name=SMED30030952-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=139bp
MVVEKFRNPDKIQPSIFYIECYSEKPTLIFEHVQKGLQVSKSDRVIKNQI
KILDRDQVDSSKSYLKDKPEIMHCPNCNEYIMTAVAHKIGRFTCLSCLVL
GVLLPYGCCLAPFCLEGFKDAIHSCPKCKKVIFEHKLV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000035Category 3 cell
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR037519LITAF_fam
IPR006629LITAF
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006629LPS-induced tumour necrosis factor alpha factorSMARTSM00714litafcoord: 69..137
e-value: 2.6E-10
score: 50.3
IPR006629LPS-induced tumour necrosis factor alpha factorPFAMPF10601zf-LITAF-likecoord: 68..134
e-value: 1.0E-18
score: 67.3
IPR006629LPS-induced tumour necrosis factor alpha factorPROSITEPS51837LITAFcoord: 54..137
score: 16.451
IPR037519LITAF domain containing proteinPANTHERPTHR23292LIPOPOLYSACCHARIDE-INDUCED TRANSCRIPTION FACTOR REGULATING TUMOR NECROSIS FACTOR ALPHAcoord: 52..136
NoneNo IPR availableTMHMMTMhelixcoord: 92..114