Thyroid hormone receptor

Overview
NameThyroid hormone receptor
Smed IDSMED30030948
Length (bp)2380
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Thyroid hormone receptor (SMED30030948) t-SNE clustered cells

Violin plots show distribution of expression levels for Thyroid hormone receptor (SMED30030948) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Thyroid hormone receptor (SMED30030948) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Thyroid hormone receptor (SMED30030948) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030948

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30030948h1SMcG0013660 SmedASXL_014235SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30030948h1SMcG0013660 SmedASXL_014235SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
pharynxSMED30030948h1SMcG0013660 dd_Smed_v4_7352_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30030948h1SMcG0013660 dd_Smed_v4_7352_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30030948h1SMcG0013660 dd_Smed_v4_7352_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynx musculatureSMED30030948h1SMcG0013660 dd_Smed_v4_7352_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynx musculatureSMED30030948h1SMcG0013660 dd_Smed_v4_13691_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Human
Match: THRA (thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796])

HSP 1 Score: 138.272 bits (347), Expect = 1.892e-34
Identity = 105/356 (29.49%), Postives = 171/356 (48.03%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK----------PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK            + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Human
Match: THRA (thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796])

HSP 1 Score: 138.272 bits (347), Expect = 1.892e-34
Identity = 105/356 (29.49%), Postives = 171/356 (48.03%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK----------PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK            + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Human
Match: THRA (thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796])

HSP 1 Score: 137.887 bits (346), Expect = 4.791e-34
Identity = 105/356 (29.49%), Postives = 171/356 (48.03%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK----------PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK            + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Human
Match: THRA (thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796])

HSP 1 Score: 136.732 bits (343), Expect = 1.968e-33
Identity = 105/356 (29.49%), Postives = 171/356 (48.03%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK----------PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK            + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Human
Match: THRA (thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796])

HSP 1 Score: 136.732 bits (343), Expect = 1.968e-33
Identity = 105/356 (29.49%), Postives = 171/356 (48.03%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK----------PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK            + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Celegans
Match: sex-1 (Steroid hormone receptor family member cnr14 [Source:UniProtKB/Swiss-Prot;Acc:P41830])

HSP 1 Score: 102.064 bits (253), Expect = 2.248e-22
Identity = 45/80 (56.25%), Postives = 56/80 (70.00%), Query Frame = 3 
Query:  846 FCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKA 1085
            FCKVCG KASG HY V +CEGCKGFFRRS+Q+K+ Y C     C I  ++R +CQ CR++ CL++GM  DSV   K R A
Sbjct:  150 FCKVCGDKASGYHYGVTSCEGCKGFFRRSIQRKIDYRCLKQQVCEIKRESRNRCQYCRFKKCLDSGMSKDSVRQMKFRNA 229
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Celegans
Match: sex-1 (Steroid hormone receptor family member cnr14 [Source:UniProtKB/Swiss-Prot;Acc:P41830])

HSP 1 Score: 102.064 bits (253), Expect = 2.248e-22
Identity = 45/80 (56.25%), Postives = 56/80 (70.00%), Query Frame = 3 
Query:  846 FCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKA 1085
            FCKVCG KASG HY V +CEGCKGFFRRS+Q+K+ Y C     C I  ++R +CQ CR++ CL++GM  DSV   K R A
Sbjct:  150 FCKVCGDKASGYHYGVTSCEGCKGFFRRSIQRKIDYRCLKQQVCEIKRESRNRCQYCRFKKCLDSGMSKDSVRQMKFRNA 229
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Celegans
Match: nhr-31 (Nuclear hormone receptor family member nhr-31 [Source:UniProtKB/Swiss-Prot;Acc:Q18192])

HSP 1 Score: 101.679 bits (252), Expect = 2.993e-22
Identity = 48/116 (41.38%), Postives = 69/116 (59.48%), Query Frame = 3 
Query:  786 KPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQAD 1133
            +P  + P V S    N G   C VCG   + LHY V+AC GCKGFFRR++  K +Y C+ + NC ++   R  C+ CR+Q C+ AGMD  +V  D+++  K    K+ R+K+KQ D
Sbjct:   23 RPSDKQPTVSSGGSQN-GDSVCAVCGDGIAKLHYGVLACYGCKGFFRRTLTGKYRYACRFSNNCIVDKFQRNSCRYCRFQRCIQAGMDPKAVRPDRDQTGKQ---KVPRIKKKQID 134
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Celegans
Match: nhr-31 (Nuclear hormone receptor family member nhr-31 [Source:UniProtKB/Swiss-Prot;Acc:Q18192])

HSP 1 Score: 101.679 bits (252), Expect = 3.935e-22
Identity = 48/116 (41.38%), Postives = 69/116 (59.48%), Query Frame = 3 
Query:  786 KPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQAD 1133
            +P  + P V S    N G   C VCG   + LHY V+AC GCKGFFRR++  K +Y C+ + NC ++   R  C+ CR+Q C+ AGMD  +V  D+++  K    K+ R+K+KQ D
Sbjct:   62 RPSDKQPTVSSGGSQN-GDSVCAVCGDGIAKLHYGVLACYGCKGFFRRTLTGKYRYACRFSNNCIVDKFQRNSCRYCRFQRCIQAGMDPKAVRPDRDQTGKQ---KVPRIKKKQID 173
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Celegans
Match: nhr-31 (Nuclear hormone receptor family member nhr-31 [Source:UniProtKB/Swiss-Prot;Acc:Q18192])

HSP 1 Score: 101.679 bits (252), Expect = 3.935e-22
Identity = 48/116 (41.38%), Postives = 69/116 (59.48%), Query Frame = 3 
Query:  786 KPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQAD 1133
            +P  + P V S    N G   C VCG   + LHY V+AC GCKGFFRR++  K +Y C+ + NC ++   R  C+ CR+Q C+ AGMD  +V  D+++  K    K+ R+K+KQ D
Sbjct:   62 RPSDKQPTVSSGGSQN-GDSVCAVCGDGIAKLHYGVLACYGCKGFFRRTLTGKYRYACRFSNNCIVDKFQRNSCRYCRFQRCIQAGMDPKAVRPDRDQTGKQ---KVPRIKKKQID 173
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Fly
Match: usp (gene:FBgn0003964 transcript:FBtr0333803)

HSP 1 Score: 102.064 bits (253), Expect = 2.606e-22
Identity = 41/82 (50.00%), Postives = 58/82 (70.73%), Query Frame = 3 
Query:  846 FCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKN 1091
             C +CG +ASG HY V +CEGCKGFF+R+V+K L Y C+ N NC I+   R +CQ CR+Q CL  GM  ++V ++++R A+N
Sbjct:  103 LCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARN 184
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Fly
Match: usp (gene:FBgn0003964 transcript:FBtr0070346)

HSP 1 Score: 102.064 bits (253), Expect = 2.606e-22
Identity = 41/82 (50.00%), Postives = 58/82 (70.73%), Query Frame = 3 
Query:  846 FCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKN 1091
             C +CG +ASG HY V +CEGCKGFF+R+V+K L Y C+ N NC I+   R +CQ CR+Q CL  GM  ++V ++++R A+N
Sbjct:  103 LCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARN 184
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Fly
Match: Eip78C (gene:FBgn0004865 transcript:FBtr0078306)

HSP 1 Score: 102.834 bits (255), Expect = 3.969e-22
Identity = 46/83 (55.42%), Postives = 58/83 (69.88%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNEL 1097
            CKVCG KASG HY V +CEGCKGFFRRS+QK+++Y C  +G C +   NR +CQ CR++ CL+AGM  DSV   +  K   EL
Sbjct:  363 CKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRCLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVRYGRVPKRSREL 445
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Fly
Match: Eip78C (gene:FBgn0004865 transcript:FBtr0306158)

HSP 1 Score: 102.834 bits (255), Expect = 3.969e-22
Identity = 46/83 (55.42%), Postives = 58/83 (69.88%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNEL 1097
            CKVCG KASG HY V +CEGCKGFFRRS+QK+++Y C  +G C +   NR +CQ CR++ CL+AGM  DSV   +  K   EL
Sbjct:  363 CKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRCLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVRYGRVPKRSREL 445
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Fly
Match: Eip78C (gene:FBgn0004865 transcript:FBtr0306157)

HSP 1 Score: 102.834 bits (255), Expect = 3.969e-22
Identity = 46/83 (55.42%), Postives = 58/83 (69.88%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNEL 1097
            CKVCG KASG HY V +CEGCKGFFRRS+QK+++Y C  +G C +   NR +CQ CR++ CL+AGM  DSV   +  K   EL
Sbjct:  363 CKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRCLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVRYGRVPKRSREL 445
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Zebrafish
Match: thrab (thyroid hormone receptor alpha b [Source:ZFIN;Acc:ZDB-GENE-060613-1])

HSP 1 Score: 139.813 bits (351), Expect = 2.710e-35
Identity = 106/364 (29.12%), Postives = 175/364 (48.08%), Query Frame = 3 
Query:  687 PEQESDNKCNNSDNRLIKSSPDPEAPFGRGKNGKPLTRS--PFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKL--KYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            P+++  N+    + R +      + P  + KN +   +S   ++PSY++ +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +G C I+   R +CQ CR++ C+  GM +D VLDD +R AK  LI+ NR KRK+ +   +   R            +       + +Q          + E   QS +       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L SG +   +  LK+  L    + ++   K  A+ +L  +E+A+L  + L+ ++       E +E+     L AFE
Sbjct:    5 PKEQDPNQSEGEEKRWL------DGPKRKRKNSQCSVKSMSGYIPSYLEKDEP---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYDGCCIIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRRLIEENREKRKKEEMVKTLQNRPEPTSSEWELIRVVTEAHRHTNAQGSHWKQKRKFLPEDIGQSPVAPTSDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-SGEMAVKREQLKNGGLGVVSDAIFDLGKSLAQFNLDDTEVALLQAVLLMSSDRTGLTCVEKIEKCQEMYLLAFE 349
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Zebrafish
Match: thrab (thyroid hormone receptor alpha b [Source:ZFIN;Acc:ZDB-GENE-060613-1])

HSP 1 Score: 139.043 bits (349), Expect = 4.619e-35
Identity = 100/324 (30.86%), Postives = 159/324 (49.07%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKL--KYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY++ +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +G C I+   R +CQ CR++ C+  GM +D VLDD +R AK  LI+ NR KRK+ +   +   R            +       + +Q          + E   QS +       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L SG +   +  LK+  L    + ++   K  A+ +L  +E+A+L  + L+ ++       E +E+     L AFE
Sbjct:   33 SGYIPSYLEKDEP---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYDGCCIIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRRLIEENREKRKKEEMVKTLQNRPEPTSSEWELIRVVTEAHRHTNAQGSHWKQKRKFLPEDIGQSPVAPTSDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-SGEMAVKREQLKNGGLGVVSDAIFDLGKSLAQFNLDDTEVALLQAVLLMSSDRTGLTCVEKIEKCQEMYLLAFE 343
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Zebrafish
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 136.732 bits (343), Expect = 3.042e-34
Identity = 103/323 (31.89%), Postives = 163/323 (50.46%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASES------QTKSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQM--LTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR +R++ +   +   R     +      +      A+ +      Q +  L  + V KEA  +      + +  E  +V     SQ   +      RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     E +E+   + L AFE
Sbjct:   21 YIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENRERRRREELQKTVWDRPEPTQEEWEMIRVVTEAHMATNAQGNHWKQKRKFLSAVGV-KEAKPEDIGSAPIVNAPEGNKVDIEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLTSVERIERCQEEFLLAFE 338
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Zebrafish
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 136.732 bits (343), Expect = 3.042e-34
Identity = 103/323 (31.89%), Postives = 163/323 (50.46%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASES------QTKSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQM--LTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR +R++ +   +   R     +      +      A+ +      Q +  L  + V KEA  +      + +  E  +V     SQ   +      RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     E +E+   + L AFE
Sbjct:   21 YIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENRERRRREELQKTVWDRPEPTQEEWEMIRVVTEAHMATNAQGNHWKQKRKFLSAVGV-KEAKPEDIGSAPIVNAPEGNKVDIEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLTSVERIERCQEEFLLAFE 338
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Zebrafish
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 136.732 bits (343), Expect = 3.042e-34
Identity = 103/323 (31.89%), Postives = 163/323 (50.46%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASES------QTKSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQM--LTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR +R++ +   +   R     +      +      A+ +      Q +  L  + V KEA  +      + +  E  +V     SQ   +      RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     E +E+   + L AFE
Sbjct:   21 YIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENRERRRREELQKTVWDRPEPTQEEWEMIRVVTEAHMATNAQGNHWKQKRKFLSAVGV-KEAKPEDIGSAPIVNAPEGNKVDIEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLTSVERIERCQEEFLLAFE 338
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Xenopus
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:Xenbase;Acc:XB-GENE-991673])

HSP 1 Score: 141.739 bits (356), Expect = 5.165e-36
Identity = 101/328 (30.79%), Postives = 163/328 (49.70%), Query Frame = 3 
Query:  789 PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            P + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S  Q+     +      +      A+ +Q          + E   Q+ I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +   L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:    2 PSSMSGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVSEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLTSVERIEKCQEGFLLAFE 316
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Xenopus
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:Xenbase;Acc:XB-GENE-991673])

HSP 1 Score: 140.198 bits (352), Expect = 1.475e-35
Identity = 100/325 (30.77%), Postives = 161/325 (49.54%), Query Frame = 3 
Query:  798 RSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            R  ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S  Q+     +      +      A+ +Q          + E   Q+ I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +   L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:    7 RGGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVSEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLTSVERIEKCQEGFLLAFE 318
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Xenopus
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:Xenbase;Acc:XB-GENE-991673])

HSP 1 Score: 140.198 bits (352), Expect = 1.671e-35
Identity = 103/322 (31.99%), Postives = 162/322 (50.31%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXX----XXXXXXXXXXXXXXEVA-GKEASESQTKSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQM--LTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S  Q         +         VA   + S  + K   +LI   KE+  +   +  + +  E  +V     SQ   +      RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +   L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:    5 YIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVSEAHVATNAQGSHWKQKRKFLLI---KESRSEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLTSVERIEKCQEGFLLAFE 319
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Xenopus
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:Xenbase;Acc:XB-GENE-991673])

HSP 1 Score: 139.813 bits (351), Expect = 2.495e-35
Identity = 100/325 (30.77%), Postives = 161/325 (49.54%), Query Frame = 3 
Query:  798 RSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            R  ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S  Q+     +      +      A+ +Q          + E   Q+ I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +   L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:   10 RVGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVSEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLTSVERIEKCQEGFLLAFE 321
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Xenopus
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:Xenbase;Acc:XB-GENE-991673])

HSP 1 Score: 139.813 bits (351), Expect = 3.094e-35
Identity = 100/324 (30.86%), Postives = 161/324 (49.69%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S  Q+     +      +      A+ +Q          + E   Q+ I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +   L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:   27 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVSEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLTSVERIEKCQEGFLLAFE 337
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Mouse
Match: Thra (thyroid hormone receptor alpha [Source:MGI Symbol;Acc:MGI:98742])

HSP 1 Score: 139.428 bits (350), Expect = 5.103e-35
Identity = 107/356 (30.06%), Postives = 173/356 (48.60%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK--------PL--TRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK        PL  + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCPLKSSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Mouse
Match: Thra (thyroid hormone receptor alpha [Source:MGI Symbol;Acc:MGI:98742])

HSP 1 Score: 139.428 bits (350), Expect = 5.136e-35
Identity = 107/356 (30.06%), Postives = 173/356 (48.60%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK--------PL--TRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK        PL  + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCPLKSSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Mouse
Match: Thra (thyroid hormone receptor alpha [Source:MGI Symbol;Acc:MGI:98742])

HSP 1 Score: 138.272 bits (347), Expect = 3.581e-34
Identity = 107/356 (30.06%), Postives = 173/356 (48.60%), Query Frame = 3 
Query:  735 IKSSPDPEAPFGRGKNGK--------PL--TRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++   DPE    R  +GK        PL  + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    8 VECGSDPEENSARSPDGKRKRKNGQCPLKSSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Mouse
Match: Thrb (thyroid hormone receptor beta [Source:MGI Symbol;Acc:MGI:98743])

HSP 1 Score: 130.568 bits (327), Expect = 1.278e-31
Identity = 101/339 (29.79%), Postives = 166/339 (48.97%), Query Frame = 3 
Query:  756 EAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            E PF + ++     +  ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S   +    D+             A+ +Q          + E   Q+ I       KV++  F    ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD + + L L +G +  ++  LK+  L    + ++      +  +L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:   93 EKPFPQVQSPPHSQKKGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFE 418
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Mouse
Match: Thrb (thyroid hormone receptor beta [Source:MGI Symbol;Acc:MGI:98743])

HSP 1 Score: 128.642 bits (322), Expect = 4.445e-31
Identity = 98/322 (30.43%), Postives = 159/322 (49.38%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S   +    D+             A+ +Q          + E   Q+ I       KV++  F    ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD + + L L +G +  ++  LK+  L    + ++      +  +L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:   96 YIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFE 404
[Close]
BLAST of Thyroid hormone receptor vs. UniProt/SwissProt
Match: sp|Q02965|THB_LITCT (Thyroid hormone receptor beta OS=Lithobates catesbeianus OX=8400 GN=thrb PE=2 SV=2)

HSP 1 Score: 142.51 bits (358), Expect = 1.276e-35
Identity = 100/328 (30.49%), Postives = 164/328 (50.00%), Query Frame = 3 
Query:  789 PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            P + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   +  Q+     +      +      A+ +Q          + E   Q+ I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:    2 PSSMSGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDELQKTLVQKPEPTPEEWELIQVVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDTEVALLQAVLLMSSDRPGLSSVERIEKCQEGFLLAFE 316
[Close]
BLAST of Thyroid hormone receptor vs. UniProt/SwissProt
Match: sp|P18117|THBA_XENLA (Thyroid hormone receptor beta-A OS=Xenopus laevis OX=8355 GN=thrb-a PE=1 SV=1)

HSP 1 Score: 142.124 bits (357), Expect = 1.869e-35
Identity = 101/328 (30.79%), Postives = 163/328 (49.70%), Query Frame = 3 
Query:  789 PLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            P + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+ NR KR++ +   S  Q+     +      +      A+ +Q          + E   Q+ I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +   L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:    2 PSSMSGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDNKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLASVERIEKCQEGFLLAFE 316
[Close]
BLAST of Thyroid hormone receptor vs. UniProt/SwissProt
Match: sp|P18119|THBB_XENLA (Thyroid hormone receptor beta-B OS=Xenopus laevis OX=8355 GN=thrb-b PE=2 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 3.798e-34
Identity = 101/324 (31.17%), Postives = 160/324 (49.38%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C   GM  D VLDD +R AK +LI+ NR KR++ +   S  QR     +      +      A+ +Q          + E   Q+ I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +   L  +E+A+L  + L+ ++ P     E +E+     L AFE
Sbjct:   47 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCKTVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSIVQRPEPTQEEWELIQVVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLSSVERIEKCQEGFLLAFE 357
[Close]
BLAST of Thyroid hormone receptor vs. UniProt/SwissProt
Match: sp|Q28570|THA_SHEEP (Thyroid hormone receptor alpha OS=Ovis aries OX=9940 GN=THRA PE=2 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 7.383e-34
Identity = 105/361 (29.09%), Postives = 174/361 (48.20%), Query Frame = 3 
Query:  690 EQESDNKCNNSDNRLIKSSPDPEAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++ S  +C +        SPD +     G+     + S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +  C I+   R +CQ CR++ C+  GM +D VLDD +R AK +LI+ NR +R++ +   S  QR     +      +      ++ +Q          + +   QS I       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L SG +   +  LK+  L    + +++  K  +  +L  +E+A+L  + L+  +       + +E+     L AFE
Sbjct:    3 QKPSKVECGSDPEESSTRSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQ---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTL-SGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFE 350
[Close]
BLAST of Thyroid hormone receptor vs. UniProt/SwissProt
Match: sp|Q9W6N4|THA_HIPHI (Thyroid hormone receptor alpha OS=Hippoglossus hippoglossus OX=8267 GN=thra PE=2 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 1.392e-33
Identity = 99/322 (30.75%), Postives = 161/322 (50.00%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNN-----TPEPLEQIYTQLLAAFE 1718
            ++PSY++ +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQ CR++ C++ GM +D VLDD +R AK  LI+ NR KRK+ +   +   R            +       + +Q  S       + +   Q  +       KV++  F E     + I +  +T     RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +   +  LK+  L    + ++   K  A+ +L  +E+A++  + L+ ++     + E +EQ     L AFE
Sbjct:   48 YIPSYLEKDEP---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPAYSCKYEGCCIIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRRLIEENREKRKREEMVRTLQVRPEPDTAEWELIRMATDAHRHTNAQGSSWKQKRKFLSDDIGQGPMVPTSDGDKVDLEAFSEF----TKIMTPAIT-----RVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVKREQLKNGGLGVVSDAIFDLGKSLAQFNLDDTEVALMQAVLLMSSDRSGLTSLEKIEQCQEAYLLAFE 356
[Close]
BLAST of Thyroid hormone receptor vs. TrEMBL
Match: T1E1D3 (TR-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 200.29 bits (508), Expect = 1.643e-50
Identity = 118/327 (36.09%), Postives = 165/327 (50.46%), Query Frame = 3 
Query:  768 GRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQAD----------------FNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTK--------SLLVLIDVMKEAFEQSFI-KVEVAHFLEIQQVPSSIQSQ-----MLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHLEPLWQFAKRAAEHHLTQSEMAILTGLALL 1658
            GRG++GK L R PF+PSYMDPN GP  C VC + ASG HY+VMACEGCKGFFRR+VQ  L Y CK +  C I   NR +CQECRW+ CL  GM  D VL D+ R+AK ELI  NR K+  +D                 N+  S      +     + ++ A  E   S+T+        S   L+ ++ +    S I K ++     IQ    +   Q     ++      RV +FA  IP   +L+L  Q  L+ N   DIICL  ++ Y+     +KL  G  +       HK +EP + FA R +  ++   E++++  L LL
Sbjct:  186 GRGRHGKALARHPFIPSYMDPNNGPHLCVVCKHNASGFHYRVMACEGCKGFFRRTVQNNLVYSCKFSNKCDIQPHNRAQCQECRWRKCLEVGMAKDLVLSDEARRAKKELIAANRAKKITSDKSSNKGSNEFRDPCSPGNNDKSPFIISEEDERLIKQIKNAFDETDTSKTEINIDFGDASNSQLLHIIVDHHVTSLIMKCDIVDDANIQSAKFNFSQQFNILVIIVEPMMQRVISFAFMIPKFIQLSLNDQVVLLKNASFDIICLRNSMNYEKHNRDMKLEPGFTITKDLSSFHKLVEPTYIFASRISYLNMDCVEVSLMAALTLL 512
[Close]
BLAST of Thyroid hormone receptor vs. TrEMBL
Match: A0A0S1Z201 (Thyroid hormone receptor beta OS=Haliotis diversicolor OX=36095 GN=THRB PE=2 SV=1)

HSP 1 Score: 189.504 bits (480), Expect = 2.208e-49
Identity = 118/354 (33.33%), Postives = 188/354 (53.11%), Query Frame = 3 
Query:  804 PFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFIKVEVAHF----LEIQQVPSSIQSQMLTREYAN---RVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHK---HLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNN-----TPEPLEQIYTQLLAAFELLMA----GQPIRNSKLLIAIFSDLQALTNRLFE 1808
            P++PSYMD   GP  C VC   A+G HY+ M CEGCKGFFRR++QK LKY CK NGNC I+   R +CQECR+Q C+  GM  D VL++++RKAK +LI+ NR +RK+ +           +              E    + +SL+  I     A+E + IK     F     +  Q   +   Q L         +V  FA+ +PG  +LN+  Q  L+ + C++++CL  A  +DA    L LP+G  +    + K      +EP+++FA   A+  L Q+E+A+L  + L+ ++      PE +E++   +L A++  +A     QP+  +K+L+ + +DL+ ++ R  E
Sbjct:   34 PYIPSYMDLTNGPEPCVVCSDAATGYHYRCMTCEGCKGFFRRTIQKNLKYHCKWNGNCVIDKTTRNQCQECRFQKCVRVGMATDLVLNERQRKAKRKLIEENRERRKRDNIKGLRLDTPDNV-------------PEHMSDRDRSLIADI---CGAYEATRIKAPNIRFPLPEYDTSQTSEAEAWQQLAEVMTPSIVKVVEFAKGVPGFVQLNVDDQILLLKSCCMEVMCLRAACRFDARTQALILPNGLTVHKSALHKGSLGVLVEPIFEFALGLAKLELDQTEVALLAAVLLMQSDRSGLKEPEAVEKLQDAILGAYKRYIAENRPHQPVHWAKVLMKV-TDLRTISTRHAE 370
[Close]
BLAST of Thyroid hormone receptor vs. TrEMBL
Match: A0A0F6V015 (Thyroid hormone receptor OS=Crassostrea gigas OX=29159 PE=2 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 7.774e-48
Identity = 125/365 (34.25%), Postives = 204/365 (55.89%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFIKVEVAHFLE----IQQVPSSIQ--SQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNN-----TPEPLEQIYTQLLAAFELLMAG----QPIRNSKLLIAIFSDLQALTNRLFE--LHAPLGHQ 1832
            +P++PSYMD   GP  C VCG  A+G HY+ M CEGCKGFFRR++QK L+Y CK N  C I+ ++R +CQECR++ CLN GM  D VL++K+RKAK +LI+ NR KRKQ +         +                   +S T++   +I  +  A+EQ+ +KV +   +     I   P + Q  ++ +T     +V  FA+ +PG  +L +  Q  L+ + C++I+CL  A  YD EK+ + + +G  L  +  LK + L    EP+++FA   ++  L ++E+A+L  + L+ ++      PE +E++   +L AF+  +A     QP+  +K+L+ + +DL+ ++ R  E  L   L HQ
Sbjct:  115 TPYIPSYMDLANGPEPCVVCGDAATGYHYRCMTCEGCKGFFRRTIQKNLQYHCKWNKMCSIDKNSRNQCQECRFRKCLNVGMATDLVLNEKQRKAKRKLIEENREKRKQDNVKVKPKPTEACN----------------HDSLTETDKTIITEVTSAYEQTAVKVPIKEPVSQDDLISSDPEAWQQLAEAMTPSIV-KVVEFAKNVPGFIQLFVDDQILLLKSCCMEIMCLRAACRYDPEKETITMHNGVCL-HKSQLKSEGLGLLVEPIFEFAVGLSKLKLDKTELALLAAVLLMQSDRSGLKEPEAVEKLQDSILGAFKRYIATKRPHQPVHWAKILMKV-TDLRTISTRHAERVLCIRLDHQ 460
[Close]
BLAST of Thyroid hormone receptor vs. TrEMBL
Match: A0A4Y5MV01 (Thyroid hormone receptor OS=Mytilus coruscus OX=42192 GN=TR PE=2 SV=1)

HSP 1 Score: 186.808 bits (473), Expect = 8.408e-48
Identity = 116/355 (32.68%), Postives = 201/355 (56.62%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFIKV-----EVAHFLEIQQVPSSIQ--SQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHK---HLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNN-----TPEPLEQIYTQLLAAFELLMA----GQPIRNSKLLIAIFSDLQALTNRLFE 1808
            +P++PSYMD + GP  C VC   A+G HY+ M CEGCKGFFRR++QK L+Y CK N +C I+   R +CQ CR++ CL  GM VD VL++K+R+AK +LI+ NR KR+   F    S+   L                  E  T +  +LI+ + +A++Q+ + +     EV +       P + Q  ++ +T     +V  FA+ +PG  +L +  Q  L+ + CL+++CL  A  YDAEK+ L + +G L++   +        +EP+++FA   ++  L ++E+++L+ + L+ ++      PE +E++  ++L AF+  +A     QP+  +K+L+ + +DL+ ++ R  E
Sbjct:   94 TPYIPSYMDLSQGPEPCVVCTDAATGYHYRCMTCEGCKGFFRRTIQKNLQYHCKWNQSCIIDKTTRNQCQYCRFKKCLYVGMAVDLVLNEKQRRAKRKLIEDNRKKRQTDGFKPKASEDGCL-----------------HELMTDNDRLLINEIVQAYDQTNVTLPPKGSEVENSDPAPHSPEAWQKMAEAMTPSIV-KVVEFAKGVPGFIQLYVDDQILLLKSCCLEVMCLRAACRYDAEKETLLMHNGMLINKSQIKSEGLGVLVEPIFEFAVGLSKLQLDKTELSLLSAVLLMQSDRSGLKEPEAVEKLQDEILGAFKRYVAEKRPHQPVHWAKILMKV-TDLRTISTRHAE 429
[Close]
BLAST of Thyroid hormone receptor vs. TrEMBL
Match: A0A210PHY2 (Thyroid hormone receptor alpha OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT24186 PE=3 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 1.432e-43
Identity = 116/365 (31.78%), Postives = 186/365 (50.96%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQMLTREYAN-----------------RVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHK---HLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNN-----TPEPLEQIYTQLLAAFELLMAG----QPIRNSKLLIAIFSDLQALTNRLFE 1808
            +P++PSYMD   GP  C VCG  A+G HY+ M CEGCKGFFRR++QK L+Y CK N NC I+   R +CQECR++ C+  GM  D VL++K+RKAK +LI+ NR KRK                             EA +  TKS L   D + +      +  EV +  E        + Q ++    N                 +V  FA+ +PG  +L +  Q  L+ + C++I+CL  A  YD +++ L + +G  L    +        +EP+++FA   A+  L ++E+A+L  + L+ ++      PE +E++   +L AF+  +A     QP+  +K+L+ + +DL+ ++ R  E
Sbjct:  102 TPYIPSYMDMTNGPEPCVVCGDAATGYHYRCMTCEGCKGFFRRTIQKNLQYHCKWNSNCIIDKTTRNQCQECRYRKCVQVGMATDLVLNEKQRKAKRKLIEDNRDKRK----------------------------TEAQKVTTKSDLCPHDSLTD--NDKLLIAEVVNAYECSATKIQTKGQGMSCTDTNDPEAWQQLADAMTPSIVKVVEFAKGVPGFIQLYVDDQILLLKSCCMEIMCLRAACKYDQDQETLTMHNGMTLHKSQIKAEGLGILVEPIFEFAVGLAKLDLDKTELALLAAVLLMQSDRSGLKEPEAVEKLQDDVLGAFKRYVAVKRPLQPVHWAKILMKV-TDLRTISTRHAE 435
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Cavefish
Match: vdra (vitamin D receptor [Source:NCBI gene;Acc:103045919])

HSP 1 Score: 121.324 bits (303), Expect = 3.469e-29
Identity = 92/320 (28.75%), Postives = 145/320 (45.31%), Query Frame = 3 
Query:  813 PSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEA-----SESQTKSLLVLIDVMKEAFEQSF-------IKVEVAHFLEIQQ----VPSSIQSQM-----------LTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKL--PSGRLLDSQFVLKHKH----LEPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP 1673
            P   D N  P  C VCG KA+G H+  M CEGCKGFFRRS+++K  + C  NG+C I  DNR  CQ CR + C++ GM  + +L D+E + K ELI    LKRK+                       E A +EA     S+ QT+ +  L++   + ++ S+       + +  +  L + Q     P S +              L      +V  FA+ IPG ++L  + Q +L+ +  ++II L +  ++  E        P  +   +  V K  H    LEPL +F     + ++ + E  +L  + LL  + P
Sbjct:   13 PDEFDRN-APRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGSCTITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKKELI----LKRKE-----------------------EEAAREAQKPRLSDEQTQIISTLVEAHHKTYDDSYSDFARFRVSLNFSSLLSMYQEGTGSPDSSEDDNSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCITD-VTKAGHTLELLEPLVKFQVGLKKLNMHEEEHVLLMAICLLSPDRP 303
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Cavefish
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 120.168 bits (300), Expect = 1.286e-28
Identity = 98/326 (30.06%), Postives = 158/326 (48.47%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKL--KYVCKLNGNCPINSDNRTKCQECRWQLCLN--AGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+   A      VLDD +R AK +LI+ NR +R++ +   +   R     +      +      A+ +Q          + E   Q  I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     E +E+     L AFE
Sbjct:   58 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVVAWPQTVMVLDDSKRLAKRKLIEENRERRRREELQKTVWDRPEPSQEEWELIRIVTEAHMATNAQGNHWKQKRKFLPEDIGQGPIVNAPEGSKVDIEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLTSVERIERCQEDFLLAFE 370
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Cavefish
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 119.783 bits (299), Expect = 1.414e-28
Identity = 98/326 (30.06%), Postives = 158/326 (48.47%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLN--AGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+   A      VLDD +R AK +LI+ NR +R++ +   +   R     +      +      A+ +Q          + E   Q  I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     E +E+     L AFE
Sbjct:   28 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVVAWPQTVMVLDDSKRLAKRKLIEENRERRRREELQKTVWDRPEPSQEEWELIRIVTEAHMATNAQGNHWKQKRKFLPEDIGQGPIVNAPEGSKVDIEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLTSVERIERCQEDFLLAFE 340
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Cavefish
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 119.398 bits (298), Expect = 1.591e-28
Identity = 100/327 (30.58%), Postives = 161/327 (49.24%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKL--KYVCKLNGNCPINSDNRTKCQECRWQLCLN--AGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQT------KSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQM--LTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+   A      VLDD +R AK +LI+ NR +R++ +   +   R     +      +      A+ +Q       +  L  + V KE   +   +  + +  E  +V     SQ   +      RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     E +E+     L AFE
Sbjct:   20 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVVAWPQTVMVLDDSKRLAKRKLIEENRERRRREELQKTVWDRPEPSQEEWELIRIVTEAHMATNAQGNHWKQKRKFLSAVGV-KETKPEDIGQGPIVNAPEGSKVDIEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLTSVERIERCQEDFLLAFE 341
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Cavefish
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 119.783 bits (299), Expect = 1.602e-28
Identity = 98/326 (30.06%), Postives = 158/326 (48.47%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLN--AGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+   A      VLDD +R AK +LI+ NR +R++ +   +   R     +      +      A+ +Q          + E   Q  I       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     E +E+     L AFE
Sbjct:   30 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVVAWPQTVMVLDDSKRLAKRKLIEENRERRRREELQKTVWDRPEPSQEEWELIRIVTEAHMATNAQGNHWKQKRKFLPEDIGQGPIVNAPEGSKVDIEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLTSVERIERCQEDFLLAFE 342
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Sea Lamprey
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 142.895 bits (359), Expect = 4.093e-37
Identity = 110/352 (31.25%), Postives = 168/352 (47.73%), Query Frame = 3 
Query:  741 SSPDPEAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSF---IKVEVAHFLEIQQVPSSIQS------QMLTREYA------NRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            SS   +AP    ++G    +  ++PSY+D N     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G+C I+   R +CQECR+Q C+  GM  D VLDD +R AK  LI+ NR +RKQ +                 +  +E  G    E +   L+        A    +    +  V++ L  + V SS+        Q  T   A       RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E D L L +G +   +  LK+  L    + ++   +  A   L  +E+A+L  + L+  + P     + +E++    L A E
Sbjct:   10 SSSSCDAP---KRDGSKKHKGAYMPSYLDKNEP---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYACKYEGSCIIDRITRNQCQECRYQKCIAVGMASDLVLDDSKRLAKRRLIEENRQRRKQDE---------------KRRNVIERPGPSDKEWELIQLVTAAHCTTNAQGSQWKEHRRFLVSNCLGPESVLSSLDGDDKVDLQAFTHFTAIITPSITRVVDFAKKLPMFTELPCEDQIVLLKGCCMEIMSLRAAVRYDPESDTLTL-NGEVAVKKEQLKNGGLGLVSDAIFDLGRSLAAFSLDDTEVALLQAVLLMSTDRPGLVNVDKVEKLQDTYLLALE 339
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Sea Lamprey
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:30607])

HSP 1 Score: 107.457 bits (267), Expect = 3.740e-25
Identity = 49/96 (51.04%), Postives = 64/96 (66.67%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAK 1088
            ++PSY+        C VCG KA+G HY  + CEGCKGFFRR++QK L   YVCK +  C ++  NR +CQECR++ CL  GM  D VLDD++R AK
Sbjct:    1 YIPSYLLEGQP---CAVCGDKATGYHYHCITCEGCKGFFRRTIQKSLHVMYVCKFSETCTVDRINRNQCQECRFKKCLAVGMVTDLVLDDRKRVAK 93

HSP 2 Score: 48.1358 bits (113), Expect = 6.278e-6
Identity = 40/154 (25.97%), Postives = 77/154 (50.00%), Query Frame = 3 
Query: 1371 NRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNN-----TPEPLEQIYTQLLAAFELLMA----GQPIRNSKLLIAIFSDLQALT 1793
             RV +FA+ + G  EL  + Q  L+   C++I+ L  A+ YDA+ D L L +G +   +  LKH  L    + +++  +      L  +E+A+L  + L+ ++      P+ ++ +  + L AFE  +       P    KLL+ + +DL+ ++
Sbjct:  220 TRVVDFAKKLTGFLELPCEDQIILLKGCCMEIMSLRAAVRYDADSDTLTL-NGEVAVRRQQLKHGGLGDISDSIFELGRSLVSFELDDTEVALLQAVLLVSSDRAGLSRPDKVDWMQERYLLAFERYVQRRKHSMPFFWPKLLMKV-TDLRLIS 371
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000201.1 (pep scaffold:Pmarinus_7.0:GL476657:122907:137950:1 gene:ENSPMAG00000000180.1 transcript:ENSPMAT00000000201.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.145 bits (261), Expect = 2.412e-24
Identity = 88/346 (25.43%), Postives = 146/346 (42.20%), Query Frame = 3 
Query:  840 PFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSF-----------------IKVEVAHFL------EIQQVPSSIQSQM----------------LTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEK-------DHLKLPSGRLLDSQFVLKHKHLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP--------EPLEQIYTQLLAAF 1715
            P  C VCG KA+G H+  M CEGCKGFFRRS+++   + C   G C I  DNR  CQ CR + C + GM  + ++ ++E + K E+I    +KRK  D                   + EV   +  E Q + +  LI+  ++ ++ S+                  +     FL      ++ ++P +  S                  L      +V  FA+ IPG KEL  + Q SL+    ++II L +  ++  E        +  K   G ++ +   L  + LEPL +F     +  L ++E  +L  + L   + P        E +++  T+ L A+
Sbjct:   24 PKVCGVCGDKATGYHFNAMTCEGCKGFFRRSMKRSASFTCPFEGKCNITKDNRRHCQACRLKRCRDIGMMKELIMTEEEVQRKKEII----MKRKLED------------------SAREVHTPQLLEEQERLIATLIEAHRKTYDASYSDFSQFRPPKRGDGSPECRNATNPFLMSLLNSDMDELPKASASGAEAAAGDELSMLPHLADLVSYSIQKVIGFAKMIPGFKELCTEDQISLLKASAIEIIILRSNESFTMEDNSWTCGSNEFKYQIGDVMQAGHKL--ELLEPLVKFQVNMKKLDLHEAEHVLLMAICLFSPDRPGVQDRCRVEEVQEHLTETLRAY 345
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004045.1 (pep scaffold:Pmarinus_7.0:GL477450:33951:67473:1 gene:ENSPMAG00000003695.1 transcript:ENSPMAT00000004045.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 97.4413 bits (241), Expect = 7.894e-24
Identity = 42/101 (41.58%), Postives = 61/101 (60.40%), Query Frame = 3 
Query:  831 NTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQAD 1133
            +  P  C VCG +A+G H+  M CEGCKGFFRRS+++   + C  +G C I  DNR  CQ CR + C + GM  + ++ ++E + K E+I    +KRK  D
Sbjct:   18 DNAPRICGVCGDRATGYHFNAMTCEGCKGFFRRSMKRSASFTCPFDGRCSITKDNRRHCQSCRLKRCKDIGMMKELIMTEEELQRKKEMI----MKRKMED 114
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006803.1 (pep scaffold:Pmarinus_7.0:GL479639:153667:156574:-1 gene:ENSPMAG00000006138.1 transcript:ENSPMAT00000006803.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 94.3597 bits (233), Expect = 1.957e-22
Identity = 42/83 (50.60%), Postives = 55/83 (66.27%), Query Frame = 3 
Query:  822 MDPNTGPF-----FCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVD 1055
            +DP +G       FC VCG +ASG HY  ++CEGCKGFF+RSV+K LKY C+ + +C IN  +R +CQ CR Q C N GM  +
Sbjct:  113 VDPASGLLKLPVEFCVVCGDRASGRHYGAVSCEGCKGFFKRSVRKNLKYTCRGSQDCVINKHHRNRCQYCRLQKCFNVGMKTE 195
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Nematostella
Match: EDO39982 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8G8])

HSP 1 Score: 101.293 bits (251), Expect = 3.721e-23
Identity = 77/295 (26.10%), Postives = 134/295 (45.42%), Query Frame = 3 
Query:  843 FFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVL------IDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDA---EKDHLKLPSGRLLDSQFVLKHKHLEPLW---------QFAKRAAEHHLTQSEMAILTGLALLVNNTP 1673
              C VC  KA+G HY V  CEGCKGFF+R+VQK+L+Y C+ N +C IN   R +CQ CR++ C+ +GM   +V DD+    ++    +   ++K+        +       SS +      G  + E + + L+ +      +DV+ ++  +       A F   + +    Q          +V  + + +PG +EL L+ Q +L+    +D+      L Y +   + D L    G +L+     K + LE  W         +F  +    ++  +E + L+GL LL  + P
Sbjct:    2 LLCVVCNDKATGYHYGVFTCEGCKGFFKRTVQKQLEYTCRGNQDCDINQHTRNRCQYCRFEKCVKSGMLKQAVRDDRTPGGRHRHASLQDHRQKKQKLQGKAPKELPQNGLSSPEGPDTPEGVVSKEDENEFLIYIQQLRHDVDVIPDSPVKPPEGSPAAGFSVDKLMQYGYQE-------LYQVIQWGKNVPGFRELKLEDQITLLKTSFMDLNVF--RLAYRSICCDPDSLMFAKGIILN-----KPQCLEMGWSMDLTETTLEFCAKLRNLNMDVNEFSCLSGLVLLSPDAP 282
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Nematostella
Match: EDO27017 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAF5])

HSP 1 Score: 93.9745 bits (232), Expect = 2.426e-21
Identity = 40/96 (41.67%), Postives = 61/96 (63.54%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADF 1136
            C +CG ++SG HY V +CEGCK FF+R+VQK+L+Y C  + +C I+ +NR +CQ CR+Q CL  GM  ++V +D+    +  +  +  LK     F
Sbjct:   14 CAICGDRSSGFHYGVQSCEGCKSFFKRTVQKQLQYACVESKSCQIDKNNRIRCQYCRFQKCLALGMLKEAVREDRAPGGRPRIKSLIGLKENAETF 109
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Nematostella
Match: EDO42195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S286])

HSP 1 Score: 94.3597 bits (233), Expect = 7.307e-21
Identity = 59/214 (27.57%), Postives = 107/214 (50.00%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLV--LIDVMKEAFEQ---SFIKVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICL 1475
            C +CG ++SG HY V +CEGCK FF+R+VQK+L+Y C  + +C I+ +NR +CQ CR+Q CL  GM  ++V +D+    +  +  +                               +  KE +E+   S L+  LI    +A  +    ++++ +     +  V + ++   LT +    V N+A+ +PG  +++ + Q SL+S   L+++ L
Sbjct:   14 CAICGDRSSGFHYGVQSCEGCKSFFKRTVQKQLQYACVESKSCQIDKNNRIRCQYCRFQKCLALGMLKEAVREDRAPGGRPRIKSL-------------------------------IGLKENAETFVSSELIIQLIQARPDAIPKRRPDYLELGLNDMCPLNPVEAIME---LTLQEVEHVINWAKRVPGFCDVDKEDQISLLSEGLLEVLIL 193
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Nematostella
Match: EDO42936 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S012])

HSP 1 Score: 93.5893 bits (231), Expect = 1.528e-20
Identity = 44/97 (45.36%), Postives = 59/97 (60.82%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINR----LKRKQ 1127
            C+VCG +ASG HY VM C+GC+GFF+RSV++ L Y CK   +CPI+   R +CQ CR + C    M+ D+V    ER  +   I+ N     LKRK 
Sbjct:    4 CRVCGDRASGKHYGVMTCDGCRGFFKRSVRRNLAYQCKEKNDCPIDVARRNQCQACRLRKCFEMNMNRDAV--QHERAPRTSQIRQNSQSKPLKRKH 98
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Nematostella
Match: EDO38995 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBF2])

HSP 1 Score: 93.5893 bits (231), Expect = 1.967e-20
Identity = 39/85 (45.88%), Postives = 61/85 (71.76%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIK 1103
            CKVCG   +G HY V+ACEGCKGFF+R+V+K L Y C+ + +C I+  +R +CQ+CR+  CL AGM  ++V  +++  A ++L++
Sbjct:   13 CKVCGDNGTGKHYGVVACEGCKGFFKRTVRKNLIYTCRGSNDCFIDKVHRNRCQKCRFVKCLTAGMKKEAVQCERKPLAASQLVR 97
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Medaka
Match: thra (thyroid hormone receptor alpha [Source:NCBI gene;Acc:100049275])

HSP 1 Score: 138.658 bits (348), Expect = 6.259e-35
Identity = 99/322 (30.75%), Postives = 159/322 (49.38%), Query Frame = 3 
Query:  807 FVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            ++PSY++ +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK +G C I+   R +CQ CR++ C++ GM +D VLDD +R AK  LI+ NR KRK+ +   S   R            +       + +Q          + E   QS +       KV++  F E  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L SG +   +  LK+  L    + ++   K  A+ +L  +E+A+L  + L+ ++       + +E+     L AFE
Sbjct:   43 YIPSYLEKDEP---CVVCGDKATGYHYRCITCEGCKGFFRRTIQKSLHPSYSCKYDGCCIIDKITRNQCQLCRFKKCIDVGMAMDLVLDDSKRVAKRRLIEENREKRKKEEMVKSLQTRPEPTVDEWDLIRMVTEAHRNTNAQGAQWKQKRKFLPEKIGQSPVAPTSDGDKVDLEAFSEFTKIITPA---------ITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAIRYDPESETLTL-SGEMAVKREQLKNGGLGVVSDAIFDLGKSLAQFNLDDTEVALLQAVLLMSSDRSGLTCVDKIEKCQETYLLAFE 351
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Medaka
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:100049254])

HSP 1 Score: 135.961 bits (341), Expect = 3.281e-34
Identity = 100/339 (29.50%), Postives = 165/339 (48.67%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIK---------------INRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+                +RL+  Q +++       +    ++     +   K  S++  K      +   E F QS +       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     + +E+   + L AFE
Sbjct:    2 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDGKRLAKRKLIEENRERRRKEELQKTAWDRLEPTQEEWDLIRLVTEAHTTTNAQGSHWKQKRKFLSQAGGK------ETKPEDFGQSSVVSSPDGNKVDIEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRDQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLSSTDRIERCQEEFLLAFE 321
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Medaka
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:100049254])

HSP 1 Score: 135.961 bits (341), Expect = 3.281e-34
Identity = 100/339 (29.50%), Postives = 165/339 (48.67%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIK---------------INRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+                +RL+  Q +++       +    ++     +   K  S++  K      +   E F QS +       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     + +E+   + L AFE
Sbjct:    2 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDGKRLAKRKLIEENRERRRKEELQKTAWDRLEPTQEEWDLIRLVTEAHTTTNAQGSHWKQKRKFLSQAGGK------ETKPEDFGQSSVVSSPDGNKVDIEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRDQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLSSTDRIERCQEEFLLAFE 321
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Medaka
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:100049254])

HSP 1 Score: 135.961 bits (341), Expect = 3.281e-34
Identity = 100/339 (29.50%), Postives = 165/339 (48.67%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIK---------------INRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+                +RL+  Q +++       +    ++     +   K  S++  K      +   E F QS +       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     + +E+   + L AFE
Sbjct:    2 SGYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDGKRLAKRKLIEENRERRRKEELQKTAWDRLEPTQEEWDLIRLVTEAHTTTNAQGSHWKQKRKFLSQAGGK------ETKPEDFGQSSVVSSPDGNKVDIEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRDQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLSSTDRIERCQEEFLLAFE 321
[Close]
BLAST of Thyroid hormone receptor vs. Ensembl Medaka
Match: thrb (thyroid hormone receptor beta [Source:NCBI gene;Acc:100049254])

HSP 1 Score: 135.191 bits (339), Expect = 5.169e-34
Identity = 100/339 (29.50%), Postives = 165/339 (48.67%), Query Frame = 3 
Query:  801 SPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLK--YVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIK---------------INRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFI-------KVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHL----EPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTP-----EPLEQIYTQLLAAFE 1718
            S ++PSY+D +     C VCG KA+G HY+ + CEGCKGFFRR++QK L   Y CK  G C I+   R +CQECR++ C+  GM  D VLDD +R AK +LI+                +RL+  Q +++       +    ++     +   K  S++  K      +   E F QS +       KV++  F +  ++ +             RV +FA+ +P   EL  + Q  L+   C++I+ L  A+ YD E + L L +G +  ++  LK+  L    + ++      +  +L  SE+A+L  + LL ++ P     + +E+   + L AFE
Sbjct:    2 SCYIPSYLDKDE---LCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLNPTYACKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDGKRLAKRKLIEENRERRRKEELQKTAWDRLEPTQEEWDLIRLVTEAHTTTNAQGSHWKQKRKFLSQAGGK------ETKPEDFGQSSVVSSPDGNKVDIEAFSQFTKIITPA---------ITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTL-NGEMAVTRDQLKNGGLGVVSDAIFDLGVSLSSFNLDDSEVALLQAVILLSSDRPGLSSTDRIERCQEEFLLAFE 321
[Close]
BLAST of Thyroid hormone receptor vs. Planmine SMEST
Match: SMESG000059170.1 (SMESG000059170.1)

HSP 1 Score: 1078.93 bits (2789), Expect = 0.000e+0
Identity = 576/596 (96.64%), Postives = 577/596 (96.81%), Query Frame = 3 
Query:  228 MESKNSLSSIIPFSTIQPRNSIVPQLPQTILCKLLQKSSTETSDIINSNSSCKKTFDFVDNSSKICFKLKSEPKTSFSSSDGIFSNFSINTSSKNLAIDSHIPSIEMTDLQSTSVFSQNTIIAKYASLSPSEAVKLNPKKRLLQRHLLEKAIEPEQESDNKCNNSDNRLIKSSPDPEAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNXXXXXXXXXXXXXXXXXXXEVAGKEASESQTKSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTPEPLEQIYTQLLAAFELLMAGQPIRNSKLLIAIFSDLQALTNRLFELHAPLGHQXXXXXXXXXXXXXXXXXXXXXIGLNLGHMIANPYLVDDGTKRPKRSTPPSIYAFSYTDKNM 2015
            MESKNSLSSIIPFSTIQPRNSIVPQLPQTILCKLLQKSSTETSDIINSNSSCKKTFDFVDNSSKICFKLKSEPKTSFSSSDGIF              +SHIPSIEMTDLQSTSVFSQNTIIAKYASLSPSEAVKLNPKKRLLQRHLLEKAIEPEQESDNKCNNSDNRLIKSSPDPEAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNSSFSQRSSLLDKSSSQESLEVAGKEASESQTKSLLVLIDVMKEAFEQSFIKVE     EIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTPEPLEQIYTQLLAAFELLMAGQPIRNSKLLIAIFSDLQALTNRLFELHAPLGHQLLFDVDIDLLSSDSSVTNSSNIGLNLGHMIANPYLVDDGTKRPKRSTPPSIYAFSYTDKNM
Sbjct:    1 MESKNSLSSIIPFSTIQPRNSIVPQLPQTILCKLLQKSSTETSDIINSNSSCKKTFDFVDNSSKICFKLKSEPKTSFSSSDGIF--------------NSHIPSIEMTDLQSTSVFSQNTIIAKYASLSPSEAVKLNPKKRLLQRHLLEKAIEPEQESDNKCNNSDNRLIKSSPDPEAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFNSSFSQRSSLLDKSSSQESLEVAGKEASESQTKSLLVLIDVMKEAFEQSFIKVE-----EIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTPEPLEQIYTQLLAAFELLMAGQPIRNSKLLIAIFSDLQALTNRLFELHAPLGHQLLFDVDIDLLSSDSSVTNSSNIGLNLGHMIANPYLVDDGTKRPKRSTPPSIYAFSYTDKNM 577
[Close]
BLAST of Thyroid hormone receptor vs. Planmine SMEST
Match: SMESG000077902.1 (SMESG000077902.1)

HSP 1 Score: 233.032 bits (593), Expect = 2.130e-65
Identity = 137/393 (34.86%), Postives = 202/393 (51.40%), Query Frame = 3 
Query:  756 EAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQAD---------------------FNXXXXXXXXXXXXXXXXXXXEVAGKEAS----------------ESQTKSLLVLIDVMKEAFEQSFIKVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLKAQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHLEPLWQFAKRAAEHHLTQSEMAILTGLALLVNNTPE-----PLEQIYTQLLAAFELLMAGQPI----RNSKLLIAIFSDLQALTN 1796
            +AP+GRGK+GK L R+PF+PSYMDPNTGP  C VC + ASG HY+VMACEGCKGFFRR+VQ  LKY CK N NC I   NR +CQECRW+ CL+ GM  D VL D+ RKAK ELI  NR K+   D                     F         +     + E  +   KE+                 E    SL++  D++    + S I+    ++ E   + SSI   +L      ++ NFA  +P   EL +  Q  L+ N C DI+CL  ++ +D +   L+L +G ++    V K+K +EP + FA+R ++ ++ Q+E++++  LAL+  +         +E +   +L + +  M         R S+L   I  +L++ TN
Sbjct:  200 QAPYGRGKHGKALARNPFIPSYMDPNTGPHLCVVCKHNASGFHYRVMACEGCKGFFRRTVQNNLKYSCKFNNNCVIQPHNRAQCQECRWKKCLSVGMAKDLVLSDEARKAKKELIAANRAKKLVGDRSKDSTNNSEQSSDGDCYKKSFTLPEEDEQFICRVKKAFEETDFYAKESPTNFQNSSINHILQCIVEYHVTSLIIKCDII----DDSNIQGAKFNYSETFNILSSIVEPIL-----RKIINFAILLPNFLELTINDQIILLKNACFDIVCLRNSMNFDNKTQSLQLATGCVVSKNDVKKYKLIEPTYVFARRISKLNMDQTEISLMAALALISCDRLGLQDFMKVESLQDDILKSIDSYMKHNSFDNTHRQSELYATILPELRSTTN 583
[Close]
BLAST of Thyroid hormone receptor vs. Planmine SMEST
Match: SMESG000076268.1 (SMESG000076268.1)

HSP 1 Score: 98.2117 bits (243), Expect = 3.315e-21
Identity = 41/97 (42.27%), Postives = 67/97 (69.07%), Query Frame = 3 
Query:  849 CKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQADFN 1139
            C+VCG +ASG HY V++C+GC+GFF+RSV++ L+YVCK +  CP++   R +CQ CR++ CL+  M+ D+V  ++  ++ N      R  +K++D N
Sbjct:   34 CRVCGDRASGKHYGVLSCDGCRGFFKRSVRRNLEYVCKESNVCPVDVARRNQCQACRFKKCLSVKMNRDAVQHERAPRSYNH----KRDNQKESDIN 126
[Close]
BLAST of Thyroid hormone receptor vs. Planmine SMEST
Match: SMESG000054304.1 (SMESG000054304.1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.105e-19
Identity = 49/112 (43.75%), Postives = 62/112 (55.36%), Query Frame = 3 
Query:  738 KSSPDPEAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDK 1073
            KS P+      R K G+P    P  P  ++       C VC  KA+GLHY VM CEGCKGFF+RS+Q +  Y C+ N NC IN + R  CQ CR + C   GM  + V DD+
Sbjct:   26 KSEPEKCEVSTRRKPGRPPKIHP--PGTINGILAE--CAVCQDKATGLHYSVMTCEGCKGFFKRSIQAEKAYKCRNNNNCVINKETRNACQACRIRRCFEKGMKENLVRDDR 133
[Close]
BLAST of Thyroid hormone receptor vs. Planmine SMEST
Match: SMESG000054304.1 (SMESG000054304.1)

HSP 1 Score: 93.5893 bits (231), Expect = 1.950e-19
Identity = 49/112 (43.75%), Postives = 62/112 (55.36%), Query Frame = 3 
Query:  738 KSSPDPEAPFGRGKNGKPLTRSPFVPSYMDPNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNCPINSDNRTKCQECRWQLCLNAGMDVDSVLDDK 1073
            KS P+      R K G+P    P  P  ++       C VC  KA+GLHY VM CEGCKGFF+RS+Q +  Y C+ N NC IN + R  CQ CR + C   GM  + V DD+
Sbjct:  179 KSEPEKCEVSTRRKPGRPPKIHP--PGTINGILAE--CAVCQDKATGLHYSVMTCEGCKGFFKRSIQAEKAYKCRNNNNCVINKETRNACQACRIRRCFEKGMKENLVRDDR 286
The following BLAST results are available for this feature:
BLAST of Thyroid hormone receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
THRA1.892e-3429.49thyroid hormone receptor alpha [Source:HGNC Symbol... [more]
THRA1.892e-3429.49thyroid hormone receptor alpha [Source:HGNC Symbol... [more]
THRA4.791e-3429.49thyroid hormone receptor alpha [Source:HGNC Symbol... [more]
THRA1.968e-3329.49thyroid hormone receptor alpha [Source:HGNC Symbol... [more]
THRA1.968e-3329.49thyroid hormone receptor alpha [Source:HGNC Symbol... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sex-12.248e-2256.25Steroid hormone receptor family member cnr14 [Sou... [more]
sex-12.248e-2256.25Steroid hormone receptor family member cnr14 [Sou... [more]
nhr-312.993e-2241.38Nuclear hormone receptor family member nhr-31 [So... [more]
nhr-313.935e-2241.38Nuclear hormone receptor family member nhr-31 [So... [more]
nhr-313.935e-2241.38Nuclear hormone receptor family member nhr-31 [So... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
usp2.606e-2250.00gene:FBgn0003964 transcript:FBtr0333803[more]
usp2.606e-2250.00gene:FBgn0003964 transcript:FBtr0070346[more]
Eip78C3.969e-2255.42gene:FBgn0004865 transcript:FBtr0078306[more]
Eip78C3.969e-2255.42gene:FBgn0004865 transcript:FBtr0306158[more]
Eip78C3.969e-2255.42gene:FBgn0004865 transcript:FBtr0306157[more]
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BLAST of Thyroid hormone receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
thrab2.710e-3529.12thyroid hormone receptor alpha b [Source:ZFIN;Acc:... [more]
thrab4.619e-3530.86thyroid hormone receptor alpha b [Source:ZFIN;Acc:... [more]
thrb3.042e-3431.89thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb3.042e-3431.89thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb3.042e-3431.89thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mmel15.165e-3630.79membrane metallo-endopeptidase-like 1 [Source:Xenb... [more]
mmel11.475e-3530.77membrane metallo-endopeptidase-like 1 [Source:Xenb... [more]
mmel11.671e-3531.99membrane metallo-endopeptidase-like 1 [Source:Xenb... [more]
mmel12.495e-3530.77membrane metallo-endopeptidase-like 1 [Source:Xenb... [more]
mmel13.094e-3530.86membrane metallo-endopeptidase-like 1 [Source:Xenb... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Thra5.103e-3530.06thyroid hormone receptor alpha [Source:MGI Symbol;... [more]
Thra5.136e-3530.06thyroid hormone receptor alpha [Source:MGI Symbol;... [more]
Thra3.581e-3430.06thyroid hormone receptor alpha [Source:MGI Symbol;... [more]
Thrb1.278e-3129.79thyroid hormone receptor beta [Source:MGI Symbol;A... [more]
Thrb4.445e-3130.43thyroid hormone receptor beta [Source:MGI Symbol;A... [more]
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BLAST of Thyroid hormone receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q02965|THB_LITCT1.276e-3530.49Thyroid hormone receptor beta OS=Lithobates catesb... [more]
sp|P18117|THBA_XENLA1.869e-3530.79Thyroid hormone receptor beta-A OS=Xenopus laevis ... [more]
sp|P18119|THBB_XENLA3.798e-3431.17Thyroid hormone receptor beta-B OS=Xenopus laevis ... [more]
sp|Q28570|THA_SHEEP7.383e-3429.09Thyroid hormone receptor alpha OS=Ovis aries OX=99... [more]
sp|Q9W6N4|THA_HIPHI1.392e-3330.75Thyroid hormone receptor alpha OS=Hippoglossus hip... [more]
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BLAST of Thyroid hormone receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1E1D31.643e-5036.09TR-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
A0A0S1Z2012.208e-4933.33Thyroid hormone receptor beta OS=Haliotis diversic... [more]
A0A0F6V0157.774e-4834.25Thyroid hormone receptor OS=Crassostrea gigas OX=2... [more]
A0A4Y5MV018.408e-4832.68Thyroid hormone receptor OS=Mytilus coruscus OX=42... [more]
A0A210PHY21.432e-4331.78Thyroid hormone receptor alpha OS=Mizuhopecten yes... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
vdra3.469e-2928.75vitamin D receptor [Source:NCBI gene;Acc:103045919... [more]
thrb1.286e-2830.06thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb1.414e-2830.06thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb1.591e-2830.58thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb1.602e-2830.06thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
thrb4.093e-3731.25thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb3.740e-2551.04thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
ENSPMAT00000000201.12.412e-2425.43pep scaffold:Pmarinus_7.0:GL476657:122907:137950:1... [more]
ENSPMAT00000004045.17.894e-2441.58pep scaffold:Pmarinus_7.0:GL477450:33951:67473:1 g... [more]
ENSPMAT00000006803.11.957e-2250.60pep scaffold:Pmarinus_7.0:GL479639:153667:156574:-... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroid hormone receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO399823.721e-2326.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO270172.426e-2141.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO421957.307e-2127.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO429361.528e-2045.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO389951.967e-2045.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Thyroid hormone receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
thra6.259e-3530.75thyroid hormone receptor alpha [Source:NCBI gene;A... [more]
thrb3.281e-3429.50thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb3.281e-3429.50thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb3.281e-3429.50thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
thrb5.169e-3429.50thyroid hormone receptor beta [Source:NCBI gene;Ac... [more]
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BLAST of Thyroid hormone receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000059170.10.000e+096.64SMESG000059170.1[more]
SMESG000077902.12.130e-6534.86SMESG000077902.1[more]
SMESG000076268.13.315e-2142.27SMESG000076268.1[more]
SMESG000054304.11.105e-1943.75SMESG000054304.1[more]
SMESG000054304.11.950e-1943.75SMESG000054304.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030948 ID=SMED30030948|Name=Thyroid hormone receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=2380bp
TCTGCCTACCACTTAATTATGTAACACAAGCAGCATAAATTTTTCGTTTC
GATCTACTTTTATACTGATTGAGTTAATGTTTACTGATTGGTTAATTCTG
AGGTTAACCGTAGGTTGATTTACACTTTAAGATTCTCACCTGAATTTATT
TATTGTACATCGGAAATTTATCTGCAAATTCCAAATTCAGTATCAATTTA
ACCGATTTTATGATTTGAGATAACAGAATGGAGTCGAAAAATTCTCTTTC
ATCAATAATACCATTTTCCACAATTCAACCCAGGAATTCCATTGTACCTC
AATTACCTCAGACAATTCTGTGCAAATTATTACAGAAAAGTTCAACGGAA
ACATCAGACATTATAAATAGCAATTCCAGTTGTAAAAAAACTTTTGATTT
TGTTGACAATTCTTCGAAAATTTGCTTCAAATTAAAATCGGAGCCGAAAA
CTTCCTTCAGTTCGTCAGATGGAATTTTCAGTAATTTTTCGATTAATACC
AGCTCTAAAAATTTAGCAATAGATTCTCATATTCCATCAATAGAAATGAC
AGATTTACAGTCCACTTCTGTTTTTTCACAAAACACCATTATTGCCAAAT
ATGCATCTCTTTCACCAAGTGAGGCTGTGAAATTAAATCCGAAGAAGAGG
CTTTTACAAAGACATTTATTAGAAAAAGCTATAGAACCTGAACAGGAAAG
TGACAATAAATGCAACAATAGTGATAATAGATTGATTAAGTCTTCACCAG
ATCCGGAAGCTCCGTTTGGTCGAGGAAAAAATGGTAAACCTTTAACAAGA
AGCCCTTTTGTTCCAAGTTATATGGATCCAAATACTGGTCCTTTTTTTTG
TAAAGTATGTGGTTACAAAGCATCTGGTTTGCATTACAAAGTAATGGCAT
GCGAAGGATGTAAAGGTTTTTTTCGACGATCGGTTCAAAAAAAATTGAAA
TATGTTTGTAAATTGAATGGAAATTGTCCGATAAATTCTGACAATCGCAC
CAAATGTCAAGAATGTCGATGGCAGTTGTGTCTCAATGCGGGAATGGATG
TTGATTCGGTTCTCGATGACAAAGAACGAAAAGCTAAAAACGAGTTAATA
AAAATAAATCGATTAAAACGTAAACAAGCCGATTTCAATTCGTCTTTTTC
ACAACGCTCAAGTCTACTAGACAAATCATCATCTCAAGAATCATTGGAAG
TAGCTGGAAAAGAAGCATCTGAATCACAAACAAAATCATTATTGGTGTTG
ATAGACGTAATGAAAGAAGCTTTTGAACAATCATTTATTAAAGTTGAGGT
AGCTCATTTTTTGGAAATTCAACAGGTTCCAAGTAGTATTCAAAGTCAAA
TGTTGACTCGGGAATATGCGAACCGAGTAGCCAATTTTGCAAGAACGATT
CCAGGGATTAAGGAATTGAATTTAAAAGCGCAGAATTCTCTAGTAAGCAA
CCGTTGTTTGGATATCATTTGTCTGTGCACAGCGTTGACCTACGATGCCG
AGAAGGATCATCTGAAGTTGCCCAGTGGCAGGTTGCTAGATTCGCAGTTT
GTTCTCAAACACAAGCACCTCGAACCATTATGGCAGTTTGCCAAGAGAGC
GGCCGAACATCATTTAACTCAGTCAGAAATGGCAATTTTAACTGGATTAG
CTTTGTTGGTTAATAACACTCCTGAGCCTCTTGAACAAATTTATACGCAA
CTGCTTGCTGCTTTTGAGCTTCTTATGGCCGGTCAGCCGATTCGTAATTC
TAAATTGCTCATTGCGATTTTCTCGGATTTACAAGCTTTAACAAATCGTT
TGTTTGAGCTGCATGCTCCATTGGGCCATCAACTTCTATTTGATGTGGAC
ATAGACCTGTTGAGCAGTGATTCCTCAGTAACAAACTCGTCTAATATCGG
TTTGAATCTTGGCCACATGATTGCAAATCCGTATTTAGTTGATGACGGAA
CGAAAAGACCGAAGCGATCAACACCACCTTCAATATATGCGTTTTCGTAT
ACTGACAAGAATATGTAAATCATTGAGTCATAGAATGCTAGGGAAATATA
TTGTATAGATTTGATTCATTGCATTTTTAGACATGTCGATAACATCACTG
AAGATCGCTCCAGGGCGCAGAAACTGGATCAACTGTTATTTTCTTAATTA
AATAATGTATGTGAAAACGAAAACACGATTAGTGCCGTTAATTTATTATG
CTATTAAAAAACTCAATAATAGTCACAGAAACCCTGGCTCAGTTTCAATG
ACGTTTACCTAGGATTAACGTCCTAATAGACAGGGACATGGCACCGGAAT
TATAGCTTTCTTTTATTTATAAAATTATTACTGAGTTTCGTTAAGCCTTG
AGTCATGTTTTTATACATTATGCACGGCAG
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protein sequence of SMED30030948-orf-1

>SMED30030948-orf-1 ID=SMED30030948-orf-1|Name=SMED30030948-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=597bp
MESKNSLSSIIPFSTIQPRNSIVPQLPQTILCKLLQKSSTETSDIINSNS
SCKKTFDFVDNSSKICFKLKSEPKTSFSSSDGIFSNFSINTSSKNLAIDS
HIPSIEMTDLQSTSVFSQNTIIAKYASLSPSEAVKLNPKKRLLQRHLLEK
AIEPEQESDNKCNNSDNRLIKSSPDPEAPFGRGKNGKPLTRSPFVPSYMD
PNTGPFFCKVCGYKASGLHYKVMACEGCKGFFRRSVQKKLKYVCKLNGNC
PINSDNRTKCQECRWQLCLNAGMDVDSVLDDKERKAKNELIKINRLKRKQ
ADFNSSFSQRSSLLDKSSSQESLEVAGKEASESQTKSLLVLIDVMKEAFE
QSFIKVEVAHFLEIQQVPSSIQSQMLTREYANRVANFARTIPGIKELNLK
AQNSLVSNRCLDIICLCTALTYDAEKDHLKLPSGRLLDSQFVLKHKHLEP
LWQFAKRAAEHHLTQSEMAILTGLALLVNNTPEPLEQIYTQLLAAFELLM
AGQPIRNSKLLIAIFSDLQALTNRLFELHAPLGHQLLFDVDIDLLSSDSS
VTNSSNIGLNLGHMIANPYLVDDGTKRPKRSTPPSIYAFSYTDKNM*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004879RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003677DNA binding
GO:0004887thyroid hormone receptor activity
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0008270zinc ion binding
GO:0043565sequence-specific DNA binding
GO:0003707steroid hormone receptor activity
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0042025host cell nucleus
GO:0005634nucleus
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000101muscle cell
PLANA:0000478pharynx musculature
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR035500NHR-like_dom_sf
IPR001728ThyrH_rcpt
IPR001628Znf_hrmn_rcpt
IPR013088Znf_NHR/GATA
IPR000536Nucl_hrmn_rcpt_lig-bd
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0043401steroid hormone mediated signaling pathway
GO:0006351transcription, DNA-templated
GO:0030522intracellular receptor signaling pathway
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 279..299
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 154..186
NoneNo IPR availablePANTHERPTHR24082NUCLEAR HORMONE RECEPTORcoord: 166..522
NoneNo IPR availableSUPERFAMILYSSF57716Glucocorticoid receptor-like (DNA-binding domain)coord: 206..289
IPR001728Thyroid hormone receptorPRINTSPR00546THYROIDHORMRcoord: 288..306
score: 32.85
coord: 271..287
score: 58.62
coord: 373..394
score: 22.73
coord: 461..483
score: 24.14
IPR001628Zinc finger, nuclear hormone receptor-typePRINTSPR00047STROIDFINGERcoord: 224..239
score: 63.25
coord: 257..265
score: 51.48
coord: 208..224
score: 50.19
coord: 265..273
score: 44.99
IPR001628Zinc finger, nuclear hormone receptor-typeSMARTSM00399c4goldcoord: 205..276
e-value: 1.3E-33
score: 127.6
IPR001628Zinc finger, nuclear hormone receptor-typePFAMPF00105zf-C4coord: 207..274
e-value: 2.3E-27
score: 95.2
IPR001628Zinc finger, nuclear hormone receptor-typePROSITEPS51030NUCLEAR_REC_DBD_2coord: 205..280
score: 18.665
IPR013088Zinc finger, NHR/GATA-typeGENE3DG3DSA:3.30.50.10coord: 202..308
e-value: 2.4E-31
score: 109.9
IPR035500Nuclear hormone receptor-like domain superfamilyGENE3DG3DSA:1.10.565.10coord: 332..540
e-value: 1.0E-13
score: 53.2
IPR035500Nuclear hormone receptor-like domain superfamilySUPERFAMILYSSF48508Nuclear receptor ligand-binding domaincoord: 332..527
IPR000536Nuclear hormone receptor, ligand-binding domainPROSITEPS51843NR_LBDcoord: 337..551
score: 13.208