Small conductance calcium-activated potassium channel protein

Overview
NameSmall conductance calcium-activated potassium channel protein
Smed IDSMED30030809
Length (bp)1589
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Small conductance calcium-activated potassium channel protein (SMED30030809) t-SNE clustered cells

Violin plots show distribution of expression levels for Small conductance calcium-activated potassium channel protein (SMED30030809) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Small conductance calcium-activated potassium channel protein (SMED30030809) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Small conductance calcium-activated potassium channel protein (SMED30030809) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30030809

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30030809h1SMcG0004969 SmedASXL_012274SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parenchymaSMED30030809h1SMcG0004969 dd_Smed_v4_10277_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
prepharyngeal regionSMED30030809h1SMcG0004969 dd_Smed_v6_10277_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30030809h1SMcG0004969 OX_Smed_1.0.11703ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 337.806 bits (865), Expect = 6.447e-109
Identity = 177/384 (46.09%), Postives = 268/384 (69.79%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTI 1372
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K++++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M   I
Sbjct:  115 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKASLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMI 493          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 335.495 bits (859), Expect = 7.882e-108
Identity = 177/383 (46.21%), Postives = 268/383 (69.97%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAI---RRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K++++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    +  KH+R+ LQAI   R++R +K +Q K++D   ++V++ + Q  M
Sbjct:  128 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKASLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQARKLRSVKMEQRKLNDQANTLVDLAKTQNIM 505          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN3 (potassium calcium-activated channel subfamily N member 3 [Source:HGNC Symbol;Acc:HGNC:6292])

HSP 1 Score: 337.035 bits (863), Expect = 8.215e-107
Identity = 178/380 (46.84%), Postives = 267/380 (70.26%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS  L     K ++FS + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM+  RIL I LE+L+C IHP PG +       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +R CE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  264 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLY---SKDSMFS-LALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAF-SYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVM 638          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 337.806 bits (865), Expect = 1.642e-106
Identity = 176/380 (46.32%), Postives = 267/380 (70.26%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K++++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M
Sbjct:  327 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKASLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIM 701          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN1 (potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290])

HSP 1 Score: 328.561 bits (841), Expect = 8.530e-106
Identity = 173/382 (45.29%), Postives = 263/382 (68.85%), Query Frame = 2
Query:  239 NVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAI---RRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            NVG RL  R+ LF+KRK +SD  LIF MFGI++M+T  ELS  +     K +++S   LK  IS +T +LL  ++ YH+ +IQLFM+DNG +DWR+AM+  R+ +I LEL +C IHP PG +       L   +   S++   +DVLLS+PMFLR +++ RV++LHS+++ DAS++S+GALN+I FN  F+ K+LM++    VL       ++ A+W +R CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ +L  K    R  KH+R+ LQAI   +R+R +K +Q K++D   ++ ++ + Q  M
Sbjct:   88 NVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYT---KESLYS-FALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWTARLAF-TYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQVQRLRSVKIEQGKLNDQANTLTDLAKTQTVM 464          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 285.034 bits (728), Expect = 2.065e-88
Identity = 152/379 (40.11%), Postives = 246/379 (64.91%), Query Frame = 2
Query:  290 NVSDLCLIFSMFGILLMITYIEL--SIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNI--SISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACE----SYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYR---NQVYMQKTIESTQ 1384
            +VSD  L F++ GI+LMI   EL  +  +  G+  S++     LK FI FTT  LL F+ ++H I+IQLFM  N  +DW +A+S  R   IGLELLIC++ P P       +  +    N+     ++  ++V LS+ MF R + +CRV++LHS+++ DAS++S+  LNR++FN  FI K+LM++    +L     FL++ A W +R CE    +    N +++ +S+W++AITFL+VGYGD+VP++ CG++++++TGI G   +++VVAV+ARKLEL+RAE +VHNF+   +L+KQLKH+AANV++E W + K++KL  K    +  KH+R+ L AI  +R ++ DQ K+++N +S+ ++ +   N   +   + STQ
Sbjct:  216 HVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL-----LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLP-------IEFIAPFMNDRFHDKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLVEKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQ 582          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 285.419 bits (729), Expect = 2.525e-88
Identity = 152/379 (40.11%), Postives = 246/379 (64.91%), Query Frame = 2
Query:  290 NVSDLCLIFSMFGILLMITYIEL--SIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNI--SISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACE----SYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYR---NQVYMQKTIESTQ 1384
            +VSD  L F++ GI+LMI   EL  +  +  G+  S++     LK FI FTT  LL F+ ++H I+IQLFM  N  +DW +A+S  R   IGLELLIC++ P P       +  +    N+     ++  ++V LS+ MF R + +CRV++LHS+++ DAS++S+  LNR++FN  FI K+LM++    +L     FL++ A W +R CE    +    N +++ +S+W++AITFL+VGYGD+VP++ CG++++++TGI G   +++VVAV+ARKLEL+RAE +VHNF+   +L+KQLKH+AANV++E W + K++KL  K    +  KH+R+ L AI  +R ++ DQ K+++N +S+ ++ +   N   +   + STQ
Sbjct:  243 HVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL-----LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLP-------IEFIAPFMNDRFHDKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLVEKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQ 609          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 284.648 bits (727), Expect = 2.571e-88
Identity = 152/379 (40.11%), Postives = 246/379 (64.91%), Query Frame = 2
Query:  290 NVSDLCLIFSMFGILLMITYIEL--SIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNI--SISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACE----SYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYR---NQVYMQKTIESTQ 1384
            +VSD  L F++ GI+LMI   EL  +  +  G+  S++     LK FI FTT  LL F+ ++H I+IQLFM  N  +DW +A+S  R   IGLELLIC++ P P       +  +    N+     ++  ++V LS+ MF R + +CRV++LHS+++ DAS++S+  LNR++FN  FI K+LM++    +L     FL++ A W +R CE    +    N +++ +S+W++AITFL+VGYGD+VP++ CG++++++TGI G   +++VVAV+ARKLEL+RAE +VHNF+   +L+KQLKH+AANV++E W + K++KL  K    +  KH+R+ L AI  +R ++ DQ K+++N +S+ ++ +   N   +   + STQ
Sbjct:  223 HVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL-----LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLP-------IEFIAPFMNDRFHDKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLVEKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQ 589          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 284.648 bits (727), Expect = 2.711e-88
Identity = 152/379 (40.11%), Postives = 246/379 (64.91%), Query Frame = 2
Query:  290 NVSDLCLIFSMFGILLMITYIEL--SIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNI--SISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACE----SYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYR---NQVYMQKTIESTQ 1384
            +VSD  L F++ GI+LMI   EL  +  +  G+  S++     LK FI FTT  LL F+ ++H I+IQLFM  N  +DW +A+S  R   IGLELLIC++ P P       +  +    N+     ++  ++V LS+ MF R + +CRV++LHS+++ DAS++S+  LNR++FN  FI K+LM++    +L     FL++ A W +R CE    +    N +++ +S+W++AITFL+VGYGD+VP++ CG++++++TGI G   +++VVAV+ARKLEL+RAE +VHNF+   +L+KQLKH+AANV++E W + K++KL  K    +  KH+R+ L AI  +R ++ DQ K+++N +S+ ++ +   N   +   + STQ
Sbjct:  223 HVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL-----LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLP-------IEFIAPFMNDRFHDKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLVEKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQ 589          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 285.034 bits (728), Expect = 3.338e-88
Identity = 152/379 (40.11%), Postives = 246/379 (64.91%), Query Frame = 2
Query:  290 NVSDLCLIFSMFGILLMITYIEL--SIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNI--SISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACE----SYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYR---NQVYMQKTIESTQ 1384
            +VSD  L F++ GI+LMI   EL  +  +  G+  S++     LK FI FTT  LL F+ ++H I+IQLFM  N  +DW +A+S  R   IGLELLIC++ P P       +  +    N+     ++  ++V LS+ MF R + +CRV++LHS+++ DAS++S+  LNR++FN  FI K+LM++    +L     FL++ A W +R CE    +    N +++ +S+W++AITFL+VGYGD+VP++ CG++++++TGI G   +++VVAV+ARKLEL+RAE +VHNF+   +L+KQLKH+AANV++E W + K++KL  K    +  KH+R+ L AI  +R ++ DQ K+++N +S+ ++ +   N   +   + STQ
Sbjct:  223 HVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHL-----LKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCPLP-------IEFIAPFMNDRFHDKTLYAVNVFLSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLVEKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQ 589          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301949)

HSP 1 Score: 344.739 bits (883), Expect = 1.374e-112
Identity = 176/374 (47.06%), Postives = 257/374 (68.72%), Query Frame = 2
Query:  239 NVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQ 1351
            NVG RL KRK LF+KRK +SD  L+  MFGI++M+   ELS     G      F +  LK  IS +T +LL  ++ YH++++QLFMIDN  +DWR+AM+  RI  IGLEL IC IHP PG +  +    L   +  I   +VP DV LSLPMFLR +++CRV++LHS+L+ DAS++S+GALNRI+FN  F+ K+LM++    VL   +  L++ ASW +R CE +  + H +  +SMW+ AITFL VGYGD+VP + CG+ I++  G+ G GCTAL+VAV++RKLEL+RAE +VHNF++  +L+K+LK+AAANV++E WL++K+ +L  +    R   H+R+ L AI  +R++K DQ K+ DN  ++ ++ + Q
Sbjct:   62 NVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELS---SAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQ 432          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0300467)

HSP 1 Score: 343.969 bits (881), Expect = 3.063e-112
Identity = 178/376 (47.34%), Postives = 260/376 (69.15%), Query Frame = 2
Query:  239 NVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQ--LFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQ 1351
            NVG RL KRK LF+KRK +SD  L+  MFGI++M+   ELS     G      F +  LK  IS +T +LL  ++ YH++++Q  LFMIDN  +DWR+AM+  RI  IGLEL IC IHP PG +  +    L   +  I   +VP DV LSLPMFLR +++CRV++LHS+L+ DAS++S+GALNRI+FN  F+ K+LM++    VL   +  L++ ASW +R CE +  + H +  ++MW+IAITFL+VG+GD+VP + CG+ I+V TGI G GCTAL+VAV++RKLEL+RAE +VHNF++  +L+K+LK+AAANV++E WL++K+ +L  +    R   H+R+ L AI  +R++K DQ K+ DN  ++ ++ + Q
Sbjct:   62 NVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELS---SAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQ 434          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301952)

HSP 1 Score: 344.354 bits (882), Expect = 9.208e-112
Identity = 176/374 (47.06%), Postives = 257/374 (68.72%), Query Frame = 2
Query:  239 NVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQ 1351
            NVG RL KRK LF+KRK +SD  L+  MFGI++M+   ELS     G      F +  LK  IS +T +LL  ++ YH++++QLFMIDN  +DWR+AM+  RI  IGLEL IC IHP PG +  +    L   +  I   +VP DV LSLPMFLR +++CRV++LHS+L+ DAS++S+GALNRI+FN  F+ K+LM++    VL   +  L++ ASW +R CE +  + H +  +SMW+ AITFL VGYGD+VP + CG+ I++  G+ G GCTAL+VAV++RKLEL+RAE +VHNF++  +L+K+LK+AAANV++E WL++K+ +L  +    R   H+R+ L AI  +R++K DQ K+ DN  ++ ++ + Q
Sbjct:   62 NVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELS---SAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQ 432          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301954)

HSP 1 Score: 345.51 bits (885), Expect = 5.900e-111
Identity = 176/374 (47.06%), Postives = 257/374 (68.72%), Query Frame = 2
Query:  239 NVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQ 1351
            NVG RL KRK LF+KRK +SD  L+  MFGI++M+   ELS     G      F +  LK  IS +T +LL  ++ YH++++QLFMIDN  +DWR+AM+  RI  IGLEL IC IHP PG +  +    L   +  I   +VP DV LSLPMFLR +++CRV++LHS+L+ DAS++S+GALNRI+FN  F+ K+LM++    VL   +  L++ ASW +R CE +  + H +  +SMW+ AITFL VGYGD+VP + CG+ I++  G+ G GCTAL+VAV++RKLEL+RAE +VHNF++  +L+K+LK+AAANV++E WL++K+ +L  +    R   H+R+ L AI  +R++K DQ K+ DN  ++ ++ + Q
Sbjct:  225 NVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELS---SAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQ 595          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0344555)

HSP 1 Score: 344.739 bits (883), Expect = 2.895e-110
Identity = 178/376 (47.34%), Postives = 260/376 (69.15%), Query Frame = 2
Query:  239 NVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQ--LFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQ 1351
            NVG RL KRK LF+KRK +SD  L+  MFGI++M+   ELS     G      F +  LK  IS +T +LL  ++ YH++++Q  LFMIDN  +DWR+AM+  RI  IGLEL IC IHP PG +  +    L   +  I   +VP DV LSLPMFLR +++CRV++LHS+L+ DAS++S+GALNRI+FN  F+ K+LM++    VL   +  L++ ASW +R CE +  + H +  ++MW+IAITFL+VG+GD+VP + CG+ I+V TGI G GCTAL+VAV++RKLEL+RAE +VHNF++  +L+K+LK+AAANV++E WL++K+ +L  +    R   H+R+ L AI  +R++K DQ K+ DN  ++ ++ + Q
Sbjct:   62 NVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELS---SAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQ 434          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:ZFIN;Acc:ZDB-GENE-100921-56])

HSP 1 Score: 334.724 bits (857), Expect = 7.785e-106
Identity = 165/362 (45.58%), Postives = 256/362 (70.72%), Query Frame = 2
Query:  293 VSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKG-SNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQG--DNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +SD  LIF MFGI++M+   ELS  +     KS+++S + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM++ R+L+I LEL++  +HP PG  + K +   +   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN++HFN  F+ K+LM++    VL      L++ A+W +R CE Y    D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    R  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  310 LSDYALIFGMFGIVVMVIETELSWGVYS---KSSMYS-LALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELIVSAVHPVPG--DFKFMWRARLAFSYAPSQAEADLDMVLSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLMKKIDHSRVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVM 665          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:ZFIN;Acc:ZDB-GENE-100921-56])

HSP 1 Score: 334.724 bits (857), Expect = 7.785e-106
Identity = 165/362 (45.58%), Postives = 256/362 (70.72%), Query Frame = 2
Query:  293 VSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKG-SNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQG--DNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +SD  LIF MFGI++M+   ELS  +     KS+++S + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM++ R+L+I LEL++  +HP PG  + K +   +   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN++HFN  F+ K+LM++    VL      L++ A+W +R CE Y    D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    R  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  310 LSDYALIFGMFGIVVMVIETELSWGVYS---KSSMYS-LALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELIVSAVHPVPG--DFKFMWRARLAFSYAPSQAEADLDMVLSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLMKKIDHSRVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVM 665          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn1a (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a [Source:ZFIN;Acc:ZDB-GENE-070912-703])

HSP 1 Score: 327.791 bits (839), Expect = 1.008e-105
Identity = 173/388 (44.59%), Postives = 265/388 (68.30%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQ 1384
            K++G +L  R+ LF+KRK +SD  LIF MFGI++M+T  ELS + +   + S  F+   LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LELL+C IHP PG +       L   +   S++   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL       ++ A+W +R CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L K++K+ AANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M   +   Q
Sbjct:   75 KDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFA---LKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIHPIPGQYVFTWTARLA-FTYVPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQ 457          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 327.405 bits (838), Expect = 1.598e-105
Identity = 173/388 (44.59%), Postives = 265/388 (68.30%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQ 1384
            K++G +L  R+ LF+KRK +SD  LIF MFGI++M+T  ELS + +   + S  F+   LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RIL I LELL+C IHP PG +       L   +   S++   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL       ++ A+W +  CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L K++K+ AANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M   +   Q
Sbjct:   76 KDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFA---LKCLISLSTVILLCLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIHPIPGQYVFTWTARLA-FTYTPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVHVCERYHDKVEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQ 458          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn2 (potassium calcium-activated channel subfamily N member 2 [Source:ZFIN;Acc:ZDB-GENE-091116-41])

HSP 1 Score: 325.479 bits (833), Expect = 1.615e-104
Identity = 174/380 (45.79%), Postives = 263/380 (69.21%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQG--DNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K +++S + LK  IS +T +LL  +I YH+ +IQLFM+DN  +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y    D   +F  +MW+I+ITFLT+GYGDMVP + CGK + ++TGI G GCTALVVAV+A+KLEL++AE +VHNF++  +L+K++K+ AANV++E WL++K  KL  K    +  KH+R+ LQAI ++R +K +Q K++D   S+V++ + Q  M
Sbjct:  101 QNIGQKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYGKESLYS-LALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSKTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNMDVTSNFLGAMWLISITFLTIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETWLIYKNTKLVRKMDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANSLVDLAKTQNVM 475          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: KCNN2 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 [Source:NCBI gene;Acc:100145581])

HSP 1 Score: 339.347 bits (869), Expect = 1.628e-108
Identity = 177/380 (46.58%), Postives = 266/380 (70.00%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K +++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    R  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M
Sbjct:  197 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKGSLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYTPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIM 571          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: KCNN2 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 [Source:NCBI gene;Acc:100145581])

HSP 1 Score: 338.961 bits (868), Expect = 1.504e-107
Identity = 177/380 (46.58%), Postives = 266/380 (70.00%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K +++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    R  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M
Sbjct:  276 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKGSLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYTPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIM 650          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: KCNN2 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 [Source:NCBI gene;Acc:100145581])

HSP 1 Score: 338.576 bits (867), Expect = 2.638e-107
Identity = 177/380 (46.58%), Postives = 266/380 (70.00%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K +++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    R  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M
Sbjct:  287 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKGSLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYTPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIM 661          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 330.872 bits (847), Expect = 5.247e-107
Identity = 177/387 (45.74%), Postives = 267/387 (68.99%), Query Frame = 2
Query:  215 GEKMSMLKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            G+K +  +NVG +L  R+ LF+KRK +SD  LIF MFGI++M+T  ELS + +   + S  F+   LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LEL +C IHP PG ++      L       S++   ID++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL       ++ A+W +R CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +LSK++K+AAANV++E WL++K+ KL  K    +  KH+R+ LQAI  +R +K +Q K++D   ++V++ + Q  M
Sbjct:   72 GQKKN--QNVGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFA---LKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIHPIPGQYSFTWTARLA-FFYTTSVANADIDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETWLIYKHTKLVRKIDHAKVRKHQRKFLQAIHLLRSVKMEQRKLNDQANTLVDLAKTQNVM 451          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 330.872 bits (847), Expect = 6.658e-107
Identity = 177/387 (45.74%), Postives = 267/387 (68.99%), Query Frame = 2
Query:  215 GEKMSMLKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            G+K +  +NVG +L  R+ LF+KRK +SD  LIF MFGI++M+T  ELS + +   + S  F+   LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LEL +C IHP PG ++      L       S++   ID++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL       ++ A+W +R CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +LSK++K+AAANV++E WL++K+ KL  K    +  KH+R+ LQAI  +R +K +Q K++D   ++V++ + Q  M
Sbjct:   64 GQKKN--QNVGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFA---LKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIHPIPGQYSFTWTARLA-FFYTTSVANADIDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETWLIYKHTKLVRKIDHAKVRKHQRKFLQAIHLLRSVKMEQRKLNDQANTLVDLAKTQNVM 443          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 [Source:MGI Symbol;Acc:MGI:2153182])

HSP 1 Score: 337.421 bits (864), Expect = 5.305e-109
Identity = 176/380 (46.32%), Postives = 267/380 (70.26%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K++++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M
Sbjct:  110 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKASLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIM 484          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 [Source:MGI Symbol;Acc:MGI:2153182])

HSP 1 Score: 337.421 bits (864), Expect = 5.305e-109
Identity = 176/380 (46.32%), Postives = 267/380 (70.26%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K++++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M
Sbjct:  110 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKASLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIM 484          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn1 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 [Source:MGI Symbol;Acc:MGI:1933993])

HSP 1 Score: 330.872 bits (847), Expect = 6.188e-107
Identity = 163/376 (43.35%), Postives = 250/376 (66.49%), Query Frame = 2
Query:  290 NVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVP------IDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQ 1384
             +SD  LIF MFGI++M+T  ELS     G        +  LK  IS +T +LL  +I YH+ +IQLF++DNG +DWR+AM+  R+ +I LEL++C IHP PG +           +  ++ S+VP      +DVLLS+PMFLR +++ RV++LHS+++ DAS++S+GALNR+ FN  F+ K+LM++    VL       ++ A+W +R CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ +L  K    R  KH+R+ LQAI ++R +K +Q KV+D   ++ E+ + Q    + +   Q
Sbjct:  103 RLSDYALIFGMFGIVVMVTETELSW----GVYTKESLCSFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSLISLELVVCAIHPVPGHYRFTW-------TARLAFSLVPSAAEADLDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSVSSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQGRVRKHQRKFLQAIHQLRSVKIEQGKVNDQANTLAELAKAQSIAYEVVSELQ 467          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn1 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 [Source:MGI Symbol;Acc:MGI:1933993])

HSP 1 Score: 330.872 bits (847), Expect = 6.188e-107
Identity = 163/376 (43.35%), Postives = 250/376 (66.49%), Query Frame = 2
Query:  290 NVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVP------IDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQ---RALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQ 1384
             +SD  LIF MFGI++M+T  ELS     G        +  LK  IS +T +LL  +I YH+ +IQLF++DNG +DWR+AM+  R+ +I LEL++C IHP PG +           +  ++ S+VP      +DVLLS+PMFLR +++ RV++LHS+++ DAS++S+GALNR+ FN  F+ K+LM++    VL       ++ A+W +R CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ +L  K    R  KH+R+ LQAI ++R +K +Q KV+D   ++ E+ + Q    + +   Q
Sbjct:  103 RLSDYALIFGMFGIVVMVTETELSW----GVYTKESLCSFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSLISLELVVCAIHPVPGHYRFTW-------TARLAFSLVPSAAEADLDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSVSSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQGRVRKHQRKFLQAIHQLRSVKIEQGKVNDQANTLAELAKAQSIAYEVVSELQ 467          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:MGI Symbol;Acc:MGI:2153183])

HSP 1 Score: 335.88 bits (860), Expect = 1.203e-106
Identity = 178/380 (46.84%), Postives = 267/380 (70.26%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS  L     K ++FS + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM+  RIL I LE+L+C IHP PG +       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +R CE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  265 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLY---SKDSMFS-LALKCLISLSTVILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAF-SYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRGVKMEQRKLSDQANTLVDLSKMQNVM 639          
BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|Q9H2S1|KCNN2_HUMAN (Small conductance calcium-activated potassium channel protein 2 OS=Homo sapiens OX=9606 GN=KCNN2 PE=1 SV=2)

HSP 1 Score: 337.806 bits (865), Expect = 3.096e-108
Identity = 177/384 (46.09%), Postives = 268/384 (69.79%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTI 1372
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K++++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M   I
Sbjct:  115 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKASLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMI 493          
BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|P70604|KCNN2_RAT (Small conductance calcium-activated potassium channel protein 2 OS=Rattus norvegicus OX=10116 GN=Kcnn2 PE=1 SV=1)

HSP 1 Score: 337.806 bits (865), Expect = 3.780e-108
Identity = 177/384 (46.09%), Postives = 268/384 (69.79%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTI 1372
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K++++S + LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LE+L+C IHP PG++       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K  KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M   I
Sbjct:  116 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYDKASLYS-LALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLA-FSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMI 494          
BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|Q7KVW5|KCNN_DROME (Small conductance calcium-activated potassium channel protein OS=Drosophila melanogaster OX=7227 GN=SK PE=2 SV=2)

HSP 1 Score: 345.125 bits (884), Expect = 2.292e-107
Identity = 176/374 (47.06%), Postives = 257/374 (68.72%), Query Frame = 2
Query:  239 NVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQ 1351
            NVG RL KRK LF+KRK +SD  L+  MFGI++M+   ELS     G      F +  LK  IS +T +LL  ++ YH++++QLFMIDN  +DWR+AM+  RI  IGLEL IC IHP PG +  +    L   +  I   +VP DV LSLPMFLR +++CRV++LHS+L+ DAS++S+GALNRI+FN  F+ K+LM++    VL   +  L++ ASW +R CE +  + H +  +SMW+ AITFL VGYGD+VP + CG+ I++  G+ G GCTAL+VAV++RKLEL+RAE +VHNF++  +L+K+LK+AAANV++E WL++K+ +L  +    R   H+R+ L AI  +R++K DQ K+ DN  ++ ++ + Q
Sbjct:  467 NVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELS---SAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQ 837          
BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|P58392|KCNN3_PIG (Small conductance calcium-activated potassium channel protein 3 OS=Sus scrofa OX=9823 GN=KCNN3 PE=2 SV=1)

HSP 1 Score: 337.035 bits (863), Expect = 2.549e-106
Identity = 178/380 (46.84%), Postives = 267/380 (70.26%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS  L     K ++FS + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM+  RIL I LE+L+C IHP PG +       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +R CE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  257 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLY---SKDSMFS-LALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAF-SYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVM 631          
BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|Q9UGI6|KCNN3_HUMAN (Small conductance calcium-activated potassium channel protein 3 OS=Homo sapiens OX=9606 GN=KCNN3 PE=1 SV=2)

HSP 1 Score: 337.035 bits (863), Expect = 3.945e-106
Identity = 178/380 (46.84%), Postives = 267/380 (70.26%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESY--QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS  L     K ++FS + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM+  RIL I LE+L+C IHP PG +       L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +R CE Y  Q D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  264 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLY---SKDSMFS-LALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAF-SYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVM 638          
BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A1I8FZC7 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020603g1 PE=4 SV=1)

HSP 1 Score: 461.84 bits (1187), Expect = 5.776e-156
Identity = 232/419 (55.37%), Postives = 313/419 (74.70%), Query Frame = 2
Query:  149 SMQTSTHQSPTRPRRSVFKLDPGEKMSMLKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFS-----AMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISI-SIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQT 1387
            SM  S++ S    +   +K +         NVGARLA+RK LF +RK ++DL L F+M GI+LMI   EL +        +N+F+     ++I+K  IS TT +LL F+ WYH +DI++FMIDN ++DWRLA+++SR   + LELL+C +HP PG H +++  L+   +  + +  ++PIDV+ SLPMFLRF++VCRV+MLHS+LYQDAS+QSLGALNRIHFNF FIFKSLM+LY EYVLT M  FLF+WASWA+RACE Y G  H +F +SMW+ AITFLTVGYGD+VP S CG+ I+V+TG+FG G TALVVAVLARKLELSRAE YVHNFVI +EL KQ+KHAAAN++KEGWL +KYKK G   + LKH+RRLL +I RIR+L+ DQ +++D+++S+ E++RNQ +M  ++ + Q+
Sbjct:   24 SMNGSSYGSSVGEQPKTYKYE---------NVGARLARRKELFVRRKLIADLSLFFAMLGIVLMIVETELCM--------ANVFNKGQPGSIIVKSLISITTAILLGFITWYHYLDIKVFMIDNSIDDWRLAITMSRGFHLALELLVCAVHPIPGQHEVQM--LVYDDTKRVRLLQVIPIDVIFSLPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGQEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKKAGNTGKTLKHQRRLLHSIHRIRDLRGDQKRLADSSVSLTEMHRNQAFMMTSLTTVQS 423          
BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A267GF91 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023081g1 PE=4 SV=1)

HSP 1 Score: 461.455 bits (1186), Expect = 1.267e-155
Identity = 230/385 (59.74%), Postives = 299/385 (77.66%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISI-SIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQT 1387
            +NVGARLA+RK LF +RK ++DL L F+M GI++MI   EL I    G        ++++K  IS +T +LL F+ WYH +DI++FMIDN M+DWRLA++LSR   + +ELL+C IHP PG H +++  L    +N++ +   +PIDV+ SLPMFLRF++VCRV+MLHS+LYQDAS+QSLGALNRIHFNF FIFKSLM+LY EYVLT M  FLF+WASWA+RACE Y G  H +F +SMW+ AITFLTVGYGD+VP S CG+ I+V+TG+FG G TALVVAVLARKLELSRAE YVHNFVI +EL KQ+KHAAAN++KEGWL +KYK+ G   + LKH+RRLL +I RIREL+NDQ +++D+++S+ E+YRNQ +M   + S Q 
Sbjct:   53 ENVGARLARRKELFVRRKLIADLSLFFAMLGIVMMIIETELCI---AGIFNKAGAGSIVMKSLISVSTAILLGFISWYHYLDIKVFMIDNSMDDWRLAITLSRGFHLAMELLVCAIHPIPGQHMVQM--LAYDNTNSVRLMQAIPIDVIFSLPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGPEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKRAGNATKTLKHQRRLLHSIHRIRELRNDQKRLADSSVSLTEMYRNQGFMLTGLASVQA 432          
BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A1I8ITN7 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 456.447 bits (1173), Expect = 3.459e-154
Identity = 217/367 (59.13%), Postives = 283/367 (77.11%), Query Frame = 2
Query:  293 VSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISI-SIVPIDVLLSLPMFLRFFMVCRVLMLHSQ-LYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQT 1387
            ++DL L F+M GI++MI   EL I    G        ++++K  IS +T +LL F+ WYH +DI++FMIDN M+DWRLA++LSR   + +ELL+C IHP PG H +++  L    +N++ +   +PIDV+ SLPMFLRF++VCRV+MLHS+ LYQDAS+QSLGALNRIHFNF FIFKSLM+LY EYVLT M  FLF+WASWA+RACE Y G  H +F +SMW+ AITFLTVGYGD+VP S CG+ I+V+TG+FG G TALVVAVLARKLELSRAE YVHNFVI +EL KQ+KHAAAN++KEGWL +KYK+ G   + LKH+RRLL +I RIREL+NDQ +++D+++S+ E+YRNQ +M   + S Q 
Sbjct:   42 IADLSLFFAMLGIVMMIIETELCI---AGIFNKAGAGSIVMKSLISVSTAILLGFISWYHYLDIKVFMIDNSMDDWRLAITLSRGFHLAMELLVCAIHPIPGQHMVQM--LAYDNTNSVRLMQAIPIDVIFSLPMFLRFYLVCRVMMLHSRRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGPEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKRAGNATKTLKHQRRLLHSIHRIRELRNDQKRLADSSVSLTEMYRNQGFMLTGLASVQA 403          
BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A1I8IEB4 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 451.44 bits (1160), Expect = 6.163e-153
Identity = 213/357 (59.66%), Postives = 276/357 (77.31%), Query Frame = 2
Query:  320 MFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISI-SIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQT 1387
            M GI++MI   EL I    G        ++++K  IS +T +LL F+ WYH +DI++FMIDN M+DWRLA++LSR   + +ELL+C IHP PG H +++  L    +N++ +   +PIDV+ SLPMFLRF++VCRV+MLHS+LYQDAS+QSLGALNRIHFNF FIFKSLM+LY EYVLT M  FLF+WASWA+RACE Y G  H +F +SMW+ AITFLTVGYGD+VP S CG+ I+V+TG+FG G TALVVAVLARKLELSRAE YVHNFVI +EL KQ+KHAAAN++KEGWL +KYK+ G   + LKH+RRLL +I RIREL+NDQ +++D+++S+ E+YRNQ +M   + S Q 
Sbjct:    1 MLGIVMMIIETELCI---AGIFNKAGAGSIVMKSLISVSTAILLGFISWYHYLDIKVFMIDNSMDDWRLAITLSRGFHLAMELLVCAIHPIPGQHMVQM--LAYDNTNSVRLMQAIPIDVIFSLPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGPEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKRAGNATKTLKHQRRLLHSIHRIRELRNDQKRLADSSVSLTEMYRNQGFMLTGLASVQA 352          
BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A1I8FX22 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 425.631 bits (1093), Expect = 8.788e-143
Identity = 207/357 (57.98%), Postives = 266/357 (74.51%), Query Frame = 2
Query:  320 MFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISI-SIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQT 1387
            M GI++MI   EL I    G        ++++K  IS +T +LL F+ WYH +DI++FMIDN M+DWRLA++LSR   + +ELL+C IHP PG H +++  L    +N++ +   +PIDV+ SLPMFLRF++VCRV+MLHS+LYQDAS+QSLGALNRIHFNF FIFKSLM+LY EYVLT M  FLF+WASWA+RACE Y G  H +F +SMW+ AITFLTVGYGD+VP S CG+ I+V+TG+FG G TALVVAVLARKLELSRAE YVHNFVI +EL KQ+KHAAAN++KEGWL +KYK+ G   + LKH+RRLL +I RIR     ++     T+ + E+YRNQ +M   + S Q 
Sbjct:    1 MLGIVMMIIETELCI---AGIFNKAGAGSIVMKSLISVSTAILLGFISWYHYLDIKVFMIDNSMDDWRLAITLSRGFHLAMELLVCAIHPIPGQHMVQM--LAYDNTNSVRLMQAIPIDVIFSLPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGPEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKRAGNATKTLKHQRRLLHSIHRIRSYATIRN--GWRTVRLTEMYRNQGFMLTGLASVQA 350          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:ZFIN;Acc:ZDB-GENE-100921-56])

HSP 1 Score: 335.495 bits (859), Expect = 9.848e-107
Identity = 176/381 (46.19%), Postives = 270/381 (70.87%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNI-SISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQG--DNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS  +     KS+++S + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM++ R+L+I LELL+  +HP PG  + K V   +     I S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN++HFN  F+ K+LM++    VL      L++ A+W +R CE Y    D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    R  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  244 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVY---SKSSMYS-LALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELLVSAVHPVPG--DFKFVWRARLAFTYIPSQAEADLDMVLSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLMKKIDHSRVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVM 618          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn2 (potassium calcium-activated channel subfamily N member 2 [Source:ZFIN;Acc:ZDB-GENE-091116-41])

HSP 1 Score: 325.865 bits (834), Expect = 4.441e-105
Identity = 173/380 (45.53%), Postives = 263/380 (69.21%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K +++S + LK  IS +T +LL  +I YH+ +IQLFM+DN  +DWR+AM+  RI  I LE+L+C IHP PG +       L     + S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  +  +  +F  +MW+I+ITFLT+GYGDMVP + CGK + ++TGI G GCTALVVAV+A+KLEL++AE +VHNF++  +L+K++K+ AANV++E WL++K  KL  K    R  KH+R+ LQAI ++R +K +Q K++D   S+V++ + Q  M
Sbjct:   84 QNIGQKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYGKESLYS-LALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIHPIPGKYTFTWTARLAFYYTS-SKTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNQDVTSNFLGAMWLISITFLTIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETWLIYKNTKLVRKMDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANSLVDLAKTQNIM 458          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 258.455 bits (659), Expect = 2.074e-79
Identity = 160/387 (41.34%), Postives = 251/387 (64.86%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIF-GVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQ 1384
            K++G +L  R+ LF+KRK +SD  LIF MFGI++M+T  ELS + +   + S  F+   LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RIL I LELL+C IHP PG +       L   +   S++   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL       ++ A+W +R    +   N L    ++W++ + F  +  G  VP     KA++ +   F G GCTALVVAV+ARKLEL++AE +VHNF++  +L K++K+ AANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M   +   Q
Sbjct:   76 KDIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFA---LKCLISLSTLILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIHPIPGHYVFTWTARL-AFTYAPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVFLFWYPQNILPI--ALWLVYVIFSKLQTGSSVP---FWKAVAFLLQPFRGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQ 452          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn4 (potassium calcium-activated channel subfamily N member 4 [Source:NCBI gene;Acc:103046778])

HSP 1 Score: 257.684 bits (657), Expect = 2.229e-79
Identity = 145/360 (40.28%), Postives = 226/360 (62.78%), Query Frame = 2
Query:  317 SMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHP---FPGSHNLKIVNLLKKGSNNISISI--------VPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERR-LLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +M GILLMI + EL   +    Q  +I+ A+ +   ISF+T  LL+ +I +H  DI+LF+ID+   DWR+AM+ +R+L I LELL+C +HP   + G      V +LK  S+   I +        + I++LLS  MFLR ++V R ++LHS++   AS +S+G+LN I+F F F+ K LM+ Y    L   I   +L A+W +R CE        D   ++W+IAITFLTVGYGD+ P ++CGK + + TG+ GV CTA++VAV+ +KL L++ E +VH F++ +++SK++++AAANV++E WL+H+  +        +H +R LL+AIR  R L+  Q K+ D T  MV++ + Q+ M
Sbjct:   78 AMLGILLMIGHAELCPAVY---QPGSIY-AISINGLISFSTGCLLILIIAFHYKDIRLFIIDHNQVDWRIAMTTNRVLGISLELLVCAVHPVASYLGPDVGVQVPVLKWNSSVTPICLCQSHRETWLEIELLLSGLMFLRLYLVHRAILLHSKVLLSASYRSIGSLNNINFTFRFVLKVLMNKYPARTLLVFIMLFWLSAAWMLRLCERQAEVETGDMGTALWLIAITFLTVGYGDVSPCTSCGKVVCLFTGVMGVACTAMLVAVVTKKLALNKGEKHVHFFMMDIQISKEIRNAAANVLRECWLLHRTTQAKNNNGEHRHHQRCLLEAIRVFRHLRLKQRKLRDYTSEMVDLSKMQMIM 433          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnq1.1 (potassium voltage-gated channel subfamily Q member 1 [Source:NCBI gene;Acc:103046994])

HSP 1 Score: 50.0618 bits (118), Expect = 4.634e-6
Identity = 47/178 (26.40%), Postives = 75/178 (42.13%), Query Frame = 2
Query:  698 LRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFL-WASWAIRACE--SYQGDNHLDF---FDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKH------AAANVVKEGW 1195
            +RF  + R+L +  Q          G   R+  +  FI +       E + T  I FL L +AS+ +   E  +  GD   +F    D++W   +T  T+GYGD VPQ+  GK I     +F +   AL   +L               F + V+  ++ KH      AAA +++  W
Sbjct:  184 IRFLQILRMLHVDRQ----------GGTWRLLGSVVFIHRQ------ELITTLYIGFLALIFASYFVYLAEKDAVDGDGVTEFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIGSCFSVFAISFFALPAGILG------------SGFALKVQQKQRQKHFNRQIPAAACLIQTSW 333          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010066.1 (pep scaffold:Pmarinus_7.0:GL480376:18291:27660:1 gene:ENSPMAG00000009109.1 transcript:ENSPMAT00000010066.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 189.889 bits (481), Expect = 6.972e-58
Identity = 88/188 (46.81%), Postives = 131/188 (69.68%), Query Frame = 2
Query:  485 QLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGI 1042
            QLF++DNG +DWR+AM+  RI  IGLELLIC IHP PG++       L     + S+    +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I FN  F+ K+LM++    VL      L++ A+W +RACE Y     +  +F  +MW+I+ITFLT+GYGDMVP + CG+ + ++TGI
Sbjct:    1 QLFIVDNGADDWRIAMTYQRIFNIGLELLICAIHPIPGNYTFMWTARLAFTYVS-SVKEADVDIVLSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDPQDITSNFLAAMWLISITFLTIGYGDMVPHTYCGRGVCLLTGI 187          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006566.1 (pep scaffold:Pmarinus_7.0:GL476463:190204:191544:-1 gene:ENSPMAG00000005936.1 transcript:ENSPMAT00000006566.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 2.558e-6
Identity = 43/132 (32.58%), Postives = 62/132 (46.97%), Query Frame = 2
Query:  698 LRFFMVCRVLML--HSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLD-FFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLA 1084
            +R   VCR+L L  HSQ  Q   A++L A           F+ +++L    +  A+   LF   + AI   E    + H +   D+ W   +T  TVGYGDM P +  GK +  M  + GV   AL V V+A
Sbjct:  308 MRLLRVCRILKLSRHSQALQ-VLAKTLRA----------SFQEIVTLL---IFVAIAVVLF---ASAIYFAEVGADEAHFNSVPDAFWWAVVTLTTVGYGDMTPVTLPGKLVGSMCALTGVLLIALPVPVIA 422          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 48.1358 bits (113), Expect = 2.990e-6
Identity = 44/179 (24.58%), Postives = 73/179 (40.78%), Query Frame = 2
Query:  698 LRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWAS----WAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKH------AAANVVKEGWLVH 1204
            +RF  + R+L +  Q          G   R+  +  FI +       E + T  I FL L  S    +     E+ + +    + D++W   +T  T+GYGD VPQ+  GK I+    +F +   AL   +L               F + V+  ++ KH      AAA +++  W  H
Sbjct:   71 IRFLQILRMLHVDRQ----------GGTWRLLGSVVFIHRQ------ELITTLYIGFLGLIFSSYFVYLAEKDEAREKNEFASYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGS------------GFALKVQQKQRQKHFNRQIPAAATLIQSLWRCH 221          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Match: EDO47671 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLC9])

HSP 1 Score: 49.2914 bits (116), Expect = 2.434e-6
Identity = 43/142 (30.28%), Postives = 59/142 (41.55%), Query Frame = 2
Query:  698 LRFFMVCRV--LMLHSQLYQD------ASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNH--LDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKL 1093
            LR   + R+  L+ HS+  QD       S   LG +  I+F    +F S+M  YAE                          DN   +   ++MW   IT  T GYGD+VP++  GK I     I GV   AL V +L  K+
Sbjct:  254 LRILRIVRIFKLLRHSRRLQDLTQTVRGSTTELGLILFIYFVLVIVFSSVM-YYAE------------------------MQDNPKFVSIPEAMWYAVITTTTTGYGDIVPETALGKVIGSACCILGVLVVALPVPILQIKV 370          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Match: EDO42724 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0S6])

HSP 1 Score: 49.2914 bits (116), Expect = 2.508e-6
Identity = 27/67 (40.30%), Postives = 32/67 (47.76%), Query Frame = 2
Query:  902 CESY-QGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLEL 1099
            CE    G   +D   S W   +T  TVGYGDM PQS  GK I  +  + GV   AL V V+     L
Sbjct:  320 CEKKIPGTKFVDIPSSFWWAVVTMTTVGYGDMAPQSPSGKFIGSLCAVCGVLTIALPVPVIVNNFSL 386          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Match: EDO45172 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTZ3])

HSP 1 Score: 48.1358 bits (113), Expect = 6.564e-6
Identity = 27/86 (31.40%), Postives = 43/86 (50.00%), Query Frame = 2
Query:  941 DSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLAR-----------KLELSRAEMYVHNFVISVELSKQLKH 1165
            +S W   IT  TVGYGDM P++  GK I     IFGV   AL ++V+             +L+L + +  +H   ++  + +Q+ H
Sbjct:  345 ESFWWSLITMTTVGYGDMTPRTWEGKIIGGACAIFGVLMVALPISVIGSNFSLYYAHAQARLKLPKKKTKIHFDTLATAMPRQVCH 430          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Match: EDO49636 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFP0])

HSP 1 Score: 48.1358 bits (113), Expect = 9.059e-6
Identity = 23/96 (23.96%), Postives = 49/96 (51.04%), Query Frame = 2
Query:  941 DSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK 1228
            D++W++ +T  T+G+GD+VP S   + +     I G+   AL ++V+   L+L+  E  +  ++   +  ++    AA  ++  W   ++ K   K
Sbjct:  412 DTVWMMVVTMTTLGFGDIVPVSVVARGLVGFASILGIFLMALFISVVHEYLQLTNQEKRILAYIEKADHQQEKMEKAAACIQSCWRYRQFVKRHMK 507          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn3 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101156116])

HSP 1 Score: 336.265 bits (861), Expect = 8.275e-107
Identity = 175/380 (46.05%), Postives = 268/380 (70.53%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQG--DNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS  +     KS+++S + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM++ R+L+I LELL+  +HP PG    +    L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN++HFN  F+ K+LM++    VL      L++ A+W +R CE Y    D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    R  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  229 QNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVY---SKSSMYS-LALKCLISLSTVILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELLVSAVHPVPGDFKFQWRARLAF-SYAPSQAEADLDMVLSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLMKKIDHSRVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVM 603          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn3 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101156116])

HSP 1 Score: 336.65 bits (862), Expect = 4.070e-106
Identity = 166/361 (45.98%), Postives = 254/361 (70.36%), Query Frame = 2
Query:  293 VSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQG--DNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +SD  LIF MFGI++M+   ELS  +     KS+++S + LK  IS +T +LL  +I YH+ ++QLF+IDNG +DWR+AM++ R+L+I LELL+  +HP PG    +    L   S   S +   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN++HFN  F+ K+LM++    VL      L++ A+W +R CE Y    D   +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L+K++K+AAANV++E WL++K+ KL  K    R  KH+R+ LQAI ++R +K +Q K+SD   ++V++ + Q  M
Sbjct:  335 LSDYALIFGMFGIVVMVIETELSWGVYS---KSSMYS-LALKCLISLSTVILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELLVSAVHPVPGDFKFQWRARLAF-SYAPSQAEADLDMVLSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLMKKIDHSRVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVM 690          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn2 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101174204])

HSP 1 Score: 326.635 bits (836), Expect = 1.636e-105
Identity = 174/386 (45.08%), Postives = 266/386 (68.91%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVP------IDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K +++S + LK  IS +T +LL  +I YH+ +IQLFM+DN  +DWR+AM+  RI  I LE+L+C IHP PG++           +  ++ S VP      +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  +  +  +F  +MW+I+ITFLT+GYGDMVP + CGK + ++TGI G GCTALVVAV+A+KLEL++AE +VHNF++  +L+K++K+ AANV++E WL++K  KL  K    R  KH+R+ LQAI ++R +K +Q K++D   S+V++ + Q  M
Sbjct:   65 QNIGEKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYGKESLYS-LALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFT-------WTARLAYSYVPSRTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNQDITSNFLGAMWLISITFLTIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETWLIYKNTKLVRKMDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANSLVDLAKTQNIM 439          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn1a (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101164003])

HSP 1 Score: 328.946 bits (842), Expect = 2.993e-105
Identity = 164/369 (44.44%), Postives = 251/369 (68.02%), Query Frame = 2
Query:  293 VSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQ 1384
            +SD  LIF MFGI++M+T  ELS + +   + S  F+   LK  IS +T +LL  +I YH+ +IQLFM+DNG +DWR+AM+  RI  I LELL+C IHP PG +       L   +   S++   +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL       ++ A+W +R CE Y     +  +F  +MW+I+ITFL++GYGDMVP + CGK + ++TGI G GCTALVVAV+ARKLEL++AE +VHNF++  +L K++K+ AANV++E WL++K+ KL  K    +  KH+R+ LQAI ++R +K +Q K++D   ++V++ + Q  M   +   Q
Sbjct:  165 LSDYALIFGMFGIVVMVTETELS-WGVYTKESSYSFA---LKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIHPIPGQYVFTWTARLA-FTYTPSVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQ 528          
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn2 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101174204])

HSP 1 Score: 327.405 bits (838), Expect = 4.092e-104
Identity = 175/386 (45.34%), Postives = 265/386 (68.65%), Query Frame = 2
Query:  236 KNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVP------IDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHL--DFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWK---QRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYM 1360
            +N+G +L  R+ LF+KRK +SD  LIF MFGI++M+   ELS        K +++S + LK  IS +T +LL  +I YH+ +IQLFM+DN  +DWR+AM+  RI  I LE+L+C IHP PG++       L       + S VP      +D++LS+PMFLR +++ RV++LHS+L+ DAS++S+GALN+I+FN  F+ K+LM++    VL      L++ A+W +RACE Y  +  +  +F  +MW+I+ITFLT+GYGDMVP + CGK + ++TGI G GCTALVVAV+A+KLEL++AE +VHNF++  +L+K++K+ AANV++E WL++K  KL  K    R  KH+R+ LQAI ++R +K +Q K++D   S+V++ + Q  M
Sbjct:  211 QNIGEKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS---WGAYGKESLYS-LALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARL-------AYSYVPSRTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNQDITSNFLGAMWLISITFLTIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETWLIYKNTKLVRKMDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANSLVDLAKTQNIM 585          
BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000060715.1 (SMESG000060715.1)

HSP 1 Score: 818.535 bits (2113), Expect = 0.000e+0
Identity = 413/413 (100.00%), Postives = 413/413 (100.00%), Query Frame = 2
Query:  152 MQTSTHQSPTRPRRSVFKLDPGEKMSMLKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQTT 1390
            MQTSTHQSPTRPRRSVFKLDPGEKMSMLKNVGARLAKRKLLFKKRKNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQTT
Sbjct:    1 MQTSTHQSPTRPRRSVFKLDPGEKMSMLKNVGARLAKRKLLFKKRKNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTIESTQTT 413          
BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000036688.1 (SMESG000036688.1)

HSP 1 Score: 358.992 bits (920), Expect = 1.261e-119
Identity = 194/419 (46.30%), Postives = 283/419 (67.54%), Query Frame = 2
Query:  116 EQSSSDFDNTFSMQTSTHQSPTRPRRSVFKLDPGEKMSMLKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTI 1372
            E S S +  T++ +   ++ P  P+   F ++   K  + +NVG++LA RK  F KR+ ++DL L+F+  GI++M+   E +I    G                    +    FL+WYH I I++FM+DN ++DW LAMS+S +L + +EL+IC IHP P  +  ++ N+    S++ S+                 ++ CRV       YQDASAQSLGALNRIHFNF FIFKSLM++Y EYVLT +I  LF+WASWA+RACE Y  +   +FF+ MW++AITFL+VGYG++VP+S CG++I+V+TGIFG GCTALVVAVLARKLELSRAE YVHNFV+ +EL KQ+KHAA NV+KEGWLV K K+ G +  AL+H+RRLL++IR+IR+LKN++ +++DN ++++E++ +Q  + +++
Sbjct:   15 ENSVSKYYQTYTNEVCNNEKPENPK--PFHVN---KREIFENVGSKLAYRKSRFYKRRLIADLSLVFAALGIIIMVADTEFAISGKYG------------------IDYGASRFLVWYHKICIEIFMLDNSIDDWHLAMSVSTVLGLAIELIICSIHPIPVDY-FQVNNVTTIDSSHQSM----------------LYLDCRV-------YQDASAQSLGALNRIHFNFRFIFKSLMNVYPEYVLTLLILILFIWASWALRACEIYHLELRDNFFNCMWVVAITFLSVGYGEIVPESYCGRSIAVLTGIFGAGCTALVVAVLARKLELSRAEKYVHNFVMDIELDKQMKHAAINVIKEGWLVFKNKRSGTRNIALEHQRRLLRSIRKIRDLKNERKRLADNAVNLLEVHHSQSCLSESV 386          
BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000076156.1 (SMESG000076156.1)

HSP 1 Score: 291.967 bits (746), Expect = 2.369e-90
Identity = 163/388 (42.01%), Postives = 261/388 (67.27%), Query Frame = 2
Query:  233 LKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKG-NQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKKGSNNISISI---VPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACE-SYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRALK---HERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQVYMQKTI 1372
            +K+VG RL +RK L++KR  +SD  L F++FGIL+M+   EL   L  G  +KS+I+S ++LK  IS +T +LL  ++ YH++ IQLF  D+ +EDWR+A++   +  + LELLIC IHP PG+ N+    +  K    +S+       I+ +L++PM LRF+M+ R L+LHS++++DA ++S+GA+N++ F+  FI K+LM++    VL   I  L++  SW +R CE +     H +  + MW+IA+TFL++GYGD+VP + CG+ I++  G+ G  CTAL+VAV ARKLELS+AE +V  F++  +++K+LK+ AANV++E WL++KY KL     A K   H+R+ L+AI  +R+LK DQ K  DN+ ++V++ + Q  + +T+
Sbjct:  276 MKSVGYRLGRRKELYEKRMRISDFSLSFAIFGILVMVIDTEL---LWAGIYRKSSIYS-ILLKSLISISTIILLGLILAYHALVIQLFSCDDCIEDWRIAITWQSVAQLLLELLICSIHPIPGNFNISQYFVTPKFKGVLSVDDRLESMIEPILAVPMLLRFYMIFRSLLLHSRMFRDAGSRSIGAMNKVSFDTRFILKTLMTMCPGTVLLTFILTLWILLSWTMRMCEINTDSPKHANMLNCMWLIAVTFLSIGYGDIVPHTNCGRGIAISAGVMGSACTALLVAVFARKLELSKAEKHVTQFMLENQMTKKLKYYAANVLRETWLIYKYTKLVKHVNASKVRTHQRKFLKAIHGLRKLKIDQRKFQDNSNTLVDLAKTQNNIYETV 659          
BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000063214.1 (SMESG000063214.1)

HSP 1 Score: 285.034 bits (728), Expect = 8.439e-88
Identity = 161/397 (40.55%), Postives = 255/397 (64.23%), Query Frame = 2
Query:  167 HQSPTR---PRRSVFKLDPGEKMSMLKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKK------GSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRAL---KHERRLLQAIRRIRELKNDQSKVSDNT 1321
            H +PT+   PRR   KL   + M   K VG RL KRK L ++RK +SD  + F++FGI++M+  +EL    MK  +K + +S   LK  I  +T ML+  +++YH I++++  +D+ +EDWRL +SL RI  + LE+LIC IHPFPG       N+L K      G   IS  +V  D++L + MF R ++  R ++LHS+L  D  ++S+GA+N+++F+ +F+ K++M+LY   VL   I  + L +SW +  CE+     H D F+S+W+I ITFL++GYGD+ P + CG+ +S+  G+ G  CTALVVAV A++LEL++AE +V +F++  +LSK LK+ AANV++E WL++KY KL      +   KH+R+ L+AI  +R++K++  K+ D +
Sbjct:  242 HSTPTKSTEPRRP--KLCRNKSM---KTVGFRLGKRKTLLEQRKKISDFSVGFALFGIVVMVIELELCDN-MKLYEKKDFYS-YFLKSLIGLSTLMLIGLIVFYHFIEVKILSLDDSIEDWRLTLSLRRIFQLILEILICAIHPFPG-------NILFKWSIYLAGKKQISDRLVSFDIILGICMFSRLYLFYRSMLLHSRLLSDVGSRSIGAMNKVNFDISFLIKTMMTLYPVRVLFVFILTVILISSWILHTCENAYDSFHADMFNSIWLICITFLSIGYGDVFPHTVCGRIVSISNGLMGCACTALVVAVFAKRLELTKAERHVMDFMMENQLSKNLKYYAANVLRETWLLYKYTKLTENVNIMKIWKHQRKFLRAIYGLRKMKSELRKLEDES 624          
BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000063214.1 (SMESG000063214.1)

HSP 1 Score: 285.034 bits (728), Expect = 8.719e-88
Identity = 161/397 (40.55%), Postives = 255/397 (64.23%), Query Frame = 2
Query:  167 HQSPTR---PRRSVFKLDPGEKMSMLKNVGXXXXXXXXXXXXXXNVSDLCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLLLFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGSHNLKIVNLLKK------GSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQDASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRACESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGVGCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLVHKYKKLGWKQRAL---KHERRLLQAIRRIRELKNDQSKVSDNT 1321
            H +PT+   PRR   KL   + M   K VG RL KRK L ++RK +SD  + F++FGI++M+  +EL    MK  +K + +S   LK  I  +T ML+  +++YH I++++  +D+ +EDWRL +SL RI  + LE+LIC IHPFPG       N+L K      G   IS  +V  D++L + MF R ++  R ++LHS+L  D  ++S+GA+N+++F+ +F+ K++M+LY   VL   I  + L +SW +  CE+     H D F+S+W+I ITFL++GYGD+ P + CG+ +S+  G+ G  CTALVVAV A++LEL++AE +V +F++  +LSK LK+ AANV++E WL++KY KL      +   KH+R+ L+AI  +R++K++  K+ D +
Sbjct:  243 HSTPTKSTEPRRP--KLCRNKSM---KTVGFRLGKRKTLLEQRKKISDFSVGFALFGIVVMVIELELCDN-MKLYEKKDFYS-YFLKSLIGLSTLMLIGLIVFYHFIEVKILSLDDSIEDWRLTLSLRRIFQLILEILICAIHPFPG-------NILFKWSIYLAGKKQISDRLVSFDIILGICMFSRLYLFYRSMLLHSRLLSDVGSRSIGAMNKVNFDISFLIKTMMTLYPVRVLFVFILTVILISSWILHTCENAYDSFHADMFNSIWLICITFLSIGYGDVFPHTVCGRIVSISNGLMGCACTALVVAVFAKRLELTKAERHVMDFMMENQLSKNLKYYAANVLRETWLLYKYTKLTENVNIMKIWKHQRKFLRAIYGLRKMKSELRKLEDES 625          
The following BLAST results are available for this feature:
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNN26.447e-10946.09potassium calcium-activated channel subfamily N me... [more]
KCNN27.882e-10846.21potassium calcium-activated channel subfamily N me... [more]
KCNN38.215e-10746.84potassium calcium-activated channel subfamily N me... [more]
KCNN21.642e-10646.32potassium calcium-activated channel subfamily N me... [more]
KCNN18.530e-10645.29potassium calcium-activated channel subfamily N me... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnl-22.065e-8840.11KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-22.525e-8840.11KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-22.571e-8840.11KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-22.711e-8840.11KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
kcnl-23.338e-8840.11KCNN (Potassium K ChaNNel, calcium activated)-Like... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SK1.374e-11247.06gene:FBgn0029761 transcript:FBtr0301949[more]
SK3.063e-11247.34gene:FBgn0029761 transcript:FBtr0300467[more]
SK9.208e-11247.06gene:FBgn0029761 transcript:FBtr0301952[more]
SK5.900e-11147.06gene:FBgn0029761 transcript:FBtr0301954[more]
SK2.895e-11047.34gene:FBgn0029761 transcript:FBtr0344555[more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnn37.785e-10645.58potassium intermediate/small conductance calcium-a... [more]
kcnn37.785e-10645.58potassium intermediate/small conductance calcium-a... [more]
kcnn1a1.008e-10544.59potassium intermediate/small conductance calcium-a... [more]
kcnn1b1.598e-10544.59potassium intermediate/small conductance calcium-a... [more]
kcnn21.615e-10445.79potassium calcium-activated channel subfamily N me... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNN21.628e-10846.58potassium channel, calcium activated intermediate/... [more]
KCNN21.504e-10746.58potassium channel, calcium activated intermediate/... [more]
KCNN22.638e-10746.58potassium channel, calcium activated intermediate/... [more]
wdr175.247e-10745.74WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10... [more]
wdr176.658e-10745.74WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kcnn25.305e-10946.32potassium intermediate/small conductance calcium-a... [more]
Kcnn25.305e-10946.32potassium intermediate/small conductance calcium-a... [more]
Kcnn16.188e-10743.35potassium intermediate/small conductance calcium-a... [more]
Kcnn16.188e-10743.35potassium intermediate/small conductance calcium-a... [more]
Kcnn31.203e-10646.84potassium intermediate/small conductance calcium-a... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9H2S1|KCNN2_HUMAN3.096e-10846.09Small conductance calcium-activated potassium chan... [more]
sp|P70604|KCNN2_RAT3.780e-10846.09Small conductance calcium-activated potassium chan... [more]
sp|Q7KVW5|KCNN_DROME2.292e-10747.06Small conductance calcium-activated potassium chan... [more]
sp|P58392|KCNN3_PIG2.549e-10646.84Small conductance calcium-activated potassium chan... [more]
sp|Q9UGI6|KCNN3_HUMAN3.945e-10646.84Small conductance calcium-activated potassium chan... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8FZC75.776e-15655.37CaMBD domain-containing protein OS=Macrostomum lig... [more]
A0A267GF911.267e-15559.74CaMBD domain-containing protein OS=Macrostomum lig... [more]
A0A1I8ITN73.459e-15459.13CaMBD domain-containing protein OS=Macrostomum lig... [more]
A0A1I8IEB46.163e-15359.66CaMBD domain-containing protein OS=Macrostomum lig... [more]
A0A1I8FX228.788e-14357.98CaMBD domain-containing protein OS=Macrostomum lig... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnn39.848e-10746.19potassium intermediate/small conductance calcium-a... [more]
kcnn24.441e-10545.53potassium calcium-activated channel subfamily N me... [more]
kcnn1b2.074e-7941.34potassium intermediate/small conductance calcium-a... [more]
kcnn42.229e-7940.28potassium calcium-activated channel subfamily N me... [more]
kcnq1.14.634e-626.40potassium voltage-gated channel subfamily Q member... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000010066.16.972e-5846.81pep scaffold:Pmarinus_7.0:GL480376:18291:27660:1 g... [more]
ENSPMAT00000006566.12.558e-632.58pep scaffold:Pmarinus_7.0:GL476463:190204:191544:-... [more]
kcnq1.12.990e-624.58potassium voltage-gated channel, KQT-like subfamil... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO476712.434e-630.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO427242.508e-640.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO451726.564e-631.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496369.059e-623.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnn38.275e-10746.05small conductance calcium-activated potassium chan... [more]
kcnn34.070e-10645.98small conductance calcium-activated potassium chan... [more]
kcnn21.636e-10545.08small conductance calcium-activated potassium chan... [more]
kcnn1a2.993e-10544.44small conductance calcium-activated potassium chan... [more]
kcnn24.092e-10445.34small conductance calcium-activated potassium chan... [more]
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BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000060715.10.000e+0100.00SMESG000060715.1[more]
SMESG000036688.11.261e-11946.30SMESG000036688.1[more]
SMESG000076156.12.369e-9042.01SMESG000076156.1[more]
SMESG000063214.18.439e-8840.55SMESG000063214.1[more]
SMESG000063214.18.719e-8840.55SMESG000063214.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030809 ID=SMED30030809|Name=Small conductance calcium-activated potassium channel protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1589bp
CTCTGTCGTTAGCATTAGTTACTGCTTAAACCACGCTTTTAATTACCATT
TAAATTTCTGATCCCATTTTATATTCCAAGATTTTTAACTGTAGGAGAAT
TCAATTGCCCACAGAGAACAGTCTTCGTCCGATTTTGACAATACCTTCTC
AATGCAAACGTCTACTCACCAAAGTCCTACGAGACCCCGGCGATCGGTTT
TCAAATTGGATCCAGGCGAGAAAATGTCTATGTTGAAAAATGTTGGTGCA
AGACTTGCAAAGCGGAAATTGTTGTTCAAGAAAAGGAAAAATGTCAGCGA
TTTGTGTTTGATTTTTTCAATGTTCGGCATCTTATTGATGATAACCTACA
TTGAATTGTCCATCTTTCTAATGAAAGGAAATCAGAAATCGAATATCTTT
TCAGCCATGATCCTAAAATTGTTCATTAGTTTCACAACTTTTATGTTGCT
GCTCTTTCTAATATGGTACCATTCGATAGATATTCAACTGTTCATGATAG
ACAATGGAATGGAAGACTGGAGACTTGCGATGTCTTTGTCCAGGATTTTG
GTAATAGGTCTAGAGTTGCTCATCTGCCTTATTCATCCTTTTCCTGGCAG
TCATAATTTAAAAATAGTAAACCTACTGAAAAAGGGATCCAATAACATCA
GTATAAGTATTGTTCCAATTGATGTTCTTCTATCACTTCCTATGTTTTTA
CGATTTTTTATGGTTTGTCGTGTTTTAATGCTTCACAGTCAACTTTATCA
AGACGCATCTGCTCAGAGTTTAGGAGCACTTAATCGAATACATTTCAATT
TCGCATTCATTTTTAAGTCTTTGATGAGCTTGTATGCCGAATATGTTCTA
ACTGCAATGATAACCTTCCTTTTTCTTTGGGCCAGTTGGGCCATTAGAGC
TTGTGAATCTTATCAAGGAGATAATCACCTAGATTTCTTTGATAGCATGT
GGATCATTGCAATAACATTCTTGACAGTTGGGTACGGAGACATGGTCCCA
CAGTCTACTTGTGGAAAAGCCATTTCCGTTATGACTGGAATATTTGGCGT
AGGCTGTACAGCTCTGGTTGTTGCGGTTTTGGCGAGGAAGCTTGAATTGT
CACGCGCTGAAATGTACGTCCATAATTTTGTCATTAGCGTTGAGTTAAGT
AAACAACTGAAACATGCGGCAGCAAATGTTGTCAAAGAAGGCTGGTTGGT
ACACAAGTACAAAAAGCTCGGATGGAAACAGAGAGCCTTGAAACACGAAC
GGCGACTGTTGCAAGCTATTAGACGGATAAGGGAACTGAAAAATGACCAG
TCTAAAGTCAGTGACAATACATTATCAATGGTGGAGATTTATCGTAACCA
GGTCTACATGCAGAAAACAATAGAATCTACTCAAACAACGATATTAGAAA
TTCATAAAAAGATATTTGAAATATAAATCAAAAGTTTTGTTTATTTGTTT
TTTTTAGCGATTTACGATAGCCATTGCTGTGAATGGTTGACGACTTCATC
ATTTTTTCGGTGTAGAGATACTGAATAGATATAGAGACAATCTCAGGCAT
CCATATTTTGTTGTAATACTTTTTGGTTTTGTAGATGTG
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protein sequence of SMED30030809-orf-1

>SMED30030809-orf-1 ID=SMED30030809-orf-1|Name=SMED30030809-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=425bp
MQTSTHQSPTRPRRSVFKLDPGEKMSMLKNVGARLAKRKLLFKKRKNVSD
LCLIFSMFGILLMITYIELSIFLMKGNQKSNIFSAMILKLFISFTTFMLL
LFLIWYHSIDIQLFMIDNGMEDWRLAMSLSRILVIGLELLICLIHPFPGS
HNLKIVNLLKKGSNNISISIVPIDVLLSLPMFLRFFMVCRVLMLHSQLYQ
DASAQSLGALNRIHFNFAFIFKSLMSLYAEYVLTAMITFLFLWASWAIRA
CESYQGDNHLDFFDSMWIIAITFLTVGYGDMVPQSTCGKAISVMTGIFGV
GCTALVVAVLARKLELSRAEMYVHNFVISVELSKQLKHAAANVVKEGWLV
HKYKKLGWKQRALKHERRLLQAIRRIRELKNDQSKVSDNTLSMVEIYRNQ
VYMQKTIESTQTTILEIHKKIFEI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000419prepharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036122CaM-bd_dom_sf
IPR015449K_chnl_Ca-activ_SK
IPR004178CaM-bd_dom
IPR013099K_chnl_dom
Vocabulary: biological process
TermDefinition
GO:0006813potassium ion transport
GO:0071805potassium ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0008076voltage-gated potassium channel complex
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0016286small conductance calcium-activated potassium channel activity
GO:0005516calmodulin binding
GO:0015269calcium-activated potassium channel activity
GO:0005249voltage-gated potassium channel activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 362..382
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 100..313
e-value: 1.5E-18
score: 69.1
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 314..407
e-value: 4.8E-26
score: 92.7
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 183..352
NoneNo IPR availableTMHMMTMhelixcoord: 226..248
NoneNo IPR availableTMHMMTMhelixcoord: 84..106
NoneNo IPR availableTMHMMTMhelixcoord: 52..74
NoneNo IPR availableTMHMMTMhelixcoord: 127..149
NoneNo IPR availableTMHMMTMhelixcoord: 263..282
NoneNo IPR availableTMHMMTMhelixcoord: 164..186
NoneNo IPR availableTMHMMTMhelixcoord: 289..311
IPR015449Potassium channel, calcium-activated, SKPRINTSPR01451SKCHANNELcoord: 138..156
score: 42.11
coord: 34..54
score: 53.06
IPR015449Potassium channel, calcium-activated, SKPFAMPF03530SK_channelcoord: 34..150
e-value: 7.2E-37
score: 125.9
IPR015449Potassium channel, calcium-activated, SKPANTHERPTHR10153SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELcoord: 27..421
IPR004178Calmodulin-binding domainSMARTSM01053CaMBD_2coord: 329..402
e-value: 1.3E-13
score: 61.3
IPR004178Calmodulin-binding domainPFAMPF02888CaMBDcoord: 331..399
e-value: 1.8E-19
score: 69.7
IPR013099Potassium channel domainPFAMPF07885Ion_trans_2coord: 237..314
e-value: 4.8E-16
score: 58.5
IPR036122SK, calmodulin-binding domain superfamilySUPERFAMILYSSF81327Small-conductance potassium channelcoord: 331..404