Prominin (Prom) protein, putative
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030797 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Prominin (Prom) protein, putative vs. TrEMBL
Match: A0A5J4N486 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0003829 PE=4 SV=1) HSP 1 Score: 265.388 bits (677), Expect = 1.844e-70 Identity = 229/873 (26.23%), Postives = 396/873 (45.36%), Query Frame = 1 Query: 346 ILNNAQTVHDGGLINSILQNVQIL-----NNSNVKRD--IMPYVVSSRMTGGYVAALFFGILWILALISAMVY--------------MFYLY-FKRPNSNTNRKPIRRQFLAVRSFFAKGDKNSFSFVYSXXXXXXXXXXXXXXXXXCFCLTNANQIHRSIGESAQSYNA----------NSTAKPNAIL-PALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQELYPRV---MNPTFRLFDFIGEIRNSFKQLPDCDEGCKQFEAFF--NQPFAEVEGFPETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAV--LFVPIFL----GIVVLFFAL-SVATSLHVWPEKRPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQP-IVVTHNDT---------RLVLDEHINRFLQVNLPKIA----KSMPKSEFPLPKP--RNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKEP----MAITTFMDNVDKYISHYVININDPVMKNKLNQDQ-KKMMLLFEQFNL-------ITDRVRNIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLML 2745 I++ Q DGGL+ +L NV L +NS+ D ++ +V+++ GYV ++ FG++W + L VY + YL P + + P A R + S + Q ++ +I A+ + + ++Q+H +I S A T P L P L ++L R Y S F + +T VD++IQAT+ MQ +FN L +LGV N F+ G + N V+ S +++ T + ++ + R + RL G + C C+ A F N P +FA + FV +N+T ESV AQ G+ + + +T++ M ++I ++R+M + W + K + L+D + KL + +V+ K S SG+ LA+ +F I L GI L V L +R + G+++ LAL ML+ + FL GG + TE CRYL +Q ++V D LD HIN F+ + I K++P P+P P R+ +Y L C++N IL A++AI DTA+L+ PE++ +FI++GR+++++SL D ++ P + + L A +L F ++ EE K+P T + I +++ + + + D Y + V++++L+ DQ K+ +Q + + + ++ + P + L SL + +++NKT L + N+ FD I TP ++A ++ +FGP++M+++G CR + EA+Q C+ +V LN +W G V + T I S L+L Sbjct: 11 IVDRTQPNLDGGLLTFVLNNVVRLPGSEQDNSSTTEDHTVVSHVITTFARTGYVLSITFGLIWTILLGLTGVYICCQGRQKKKHSNGLVYLAEAGGPVTEVDTPPHNSSGWAFRE--KRTQLQSHWLCLAIQFILFIILAVLLSTGVLLGFATSSQLHANIASSPTHEEAVGRLLNSAELEHTDPPRTYLFPRLLRALAQTRAYFSEFVYYTKNHTTPIVDQLIQATEAMQDRMTNEFNTILFDKLGVSNAFELGDALGNSVISLIRHSMSIVEQDTAF----KQHFDRFKIELQTWLRLITTYGPKSDD----TSCTARCQFLRAAFTGNLTVRHDTFMPSFTFAIALKFVTTDRNQTAESVQAQINQGKILAARQLTETKQIMAERINIPKSIRDMVDQQWDAIGSQMSKAIHLVDQLASKL-TRSVAPKVSSGSGVALALGCIFWSILLLLTIGIAWLIIHYHCVPNGLRSRERRRVRAVAAFGLFI----LALCMLLAMIFFLVGGYLSTEACRYLNPSQKKVIVVKRDAPKDTYTKELMFPLDSHINEFVNHHWVIITSLAEKAVPPGGKPMPLPHIRSPIYALSHNCRENMGILGAMDAIRDFDTASLNDPELSDRFIKIGREIMLDSLRAIDVNELFPKETDEQLAMAGRLDDF-IVNFEEIRGKLPATYLSIRSSDDESGNYKLYSEEDMWETWDAY--------QNEVLRDRLSTDQWTKLAAATQQVRIRLVNLGSVVSTIDGHLKDLAKAEKVGPTLTQLQTSLFHVKEVMSNKTALIEQANQLFDKHIAAKTPDEAAKLITQFGPQLMAEVGRCRRLHEAFQDVNSAVCEGVVSLLNGFWFVYGWVAFVGTLITSFGLLLL 859
BLAST of Prominin (Prom) protein, putative vs. TrEMBL
Match: A0A183WSI6 (Uncharacterized protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS15089 PE=4 SV=1) HSP 1 Score: 259.225 bits (661), Expect = 2.491e-68 Identity = 223/880 (25.34%), Postives = 405/880 (46.02%), Query Frame = 1 Query: 331 SFANIILNNAQTVHDGGLINSILQNVQILNNSNV---------------KRDIMPYVVSSRMTGGYVAALFFGILW--ILALISAMVYMFYLYFKRPNS-------------NTNRKPIRRQFLAVRS----FFAKGDKNSFSFV-YSXXXXXXXXXXXXXXXXXCFCLTNANQIH----------RSIGESAQSYNANST-AKPNAILPALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQEL------YPRVMNPTFRLFDFIGEIRNSFKQLPDCDEGCKQFEA-FFNQPFAEVEGF-PETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAVLFVPIFLGIVVLFFALSVATSLHVWPEK---RPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQPIV-VTHND---------TRLVLDEHINRFLQVNLPKIAK-SMPKSEFPLPKPRNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKEPMAITTFMDNVDKYISHYVININDPVMK----NKLNQDQKKMMLLFEQFNLITDRVRNIFSNMKYIPSIK---PVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLML 2745 S AN I++ AQ DGG+I IL N+ L + + I +++S+ GY + +LW IL +I+ + K+ + NT+R+ I L S F+ ++ S++ + Q ++ + AI + + T + Q+H S+G + T I P L + L IR Y+S F + + V E+IQAT+ MQ +FN L +GV F+ G + VV + A++ + ++ + L + R++N D+ +C + C + F N + F PE +FA + F+ +N+T ES+ AQ HG++ N+ + +T+ M ++I ++RNMT + W ++ ++ ID I + + + ++S K S S L L + + F +++ + + H P + + + +++G + LA+ +++ L +L GG + TE CRY+ Q ++ VT D T L +D HIN F+ N P I S S P+P R+ +YG++ C+ N+ IL A+++I+ D AL+ P+++ +F+ +G++++I SL + +M P + D+L AS+L F ++ EE ++P+ + I + + +D++ K Y +I + NKLN +K+ Q + I +++I N+ + S+K P+V L L + I+NNKT L + FD I TP+++ ++ ++GPK+MSK+G CR ++ A + C+ V LN +W +G V L+ T I++ L+L Sbjct: 6 SSANAIVSRAQPSLDGGIITFILNNLVHLPTPDSSSPSSSNQTTTTSDSEVTITHHILSTYSRTGYALGIVCAVLWSIILIIIACSTCRRRKHIKKHSETLIYLAPTDNHVLNTSRQTINTGSLTHHSSKSTFYRTRERLQSSWICLAIQFALLTLLAILLGTAVILGFTASGQLHTNLITTPIHEESVGRLLTIGELDITNPDKRHIFPRLLRGLAQIRAYISEFVPQTKIDIEPIVKELIQATEKMQDRMTNEFNAILFNDIGVTEAFQLGDILGGHVVTLINKYTAIVESNKEFKNIFDRLKVEFQSWLRLVNADSPQNDY------------NCVDQCSVLRSTFMNNVSVRPDSFMPEINFAIALKFLTTDRNQTAESIQAQLNHGKELANQQLERTKSMMAEKINIPESIRNMTNKQWDQIGSQLSDVLSRIDQIFIMI-TRSISPKVSSASSLFLTLNLIFWFSILLITIGLIWLIIRYHFVPAELGLQARNRVRLGASVGYFILAISIILACLFYLIGGYLYTEGCRYINPEQNMINVTDYDPTHQNYIQKTMLPVDAHINAFINRNWPAIVSISSQLSSMPVPHIRSPIYGILHNCRDNQGILQAMDSIKDFDMKALNDPQMSERFVNLGKEIMINSLESINVDEMFPKETDDNLAMASRLDDF-IVNYEEVRLQLPKYYLSIQSPTDEAGNFTLWSVDDMWKAWEMYYTDILSYRLSVEQMNKLNSATEKVRRTLIQLDSI---IKDIDENLIVLSSLKKSAPLVMKLQNRLIDLKAIMNNKTHLIHRAVQLFDENIKAKTPEEAMNLIVEYGPKIMSKVGQCRRVYSAVDDVNNAVCNGFVSVLNGFWFLMGWVTLIGTLIITFSLLLL 868
BLAST of Prominin (Prom) protein, putative vs. TrEMBL
Match: A0A074ZPJ9 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_05281 PE=4 SV=1) HSP 1 Score: 254.988 bits (650), Expect = 8.230e-67 Identity = 225/885 (25.42%), Postives = 399/885 (45.08%), Query Frame = 1 Query: 346 ILNNAQTVHDGGLI----NSILQ-------NVQILNNSNVKRDIMPYVVSSRMTGGYVAALFFGILWILALISAMVYMFYLYFKRPNSNTNRKPIRRQFLAVRSFFAKG--------------DKNSFSFVYSXXXXXXXXXXXXXXXXXCFCL-------------TNANQIH----------RSIGE---SAQSYNANSTAKPNAILPALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQELYPRVMNPTFRLFDFIGEIRNSFKQLPD--CDEGCKQF-EAFFNQPFAEVEGF-PETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAV------LFVPIFLGIVVLFFAL-SVATSLHVWPEKRPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQPIV--VTHN--------DTRLVLDEHINRFLQVNLPKIA----KSMPKSEFPLPKP--RNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKE------PMAITTFMDNVDKYISH-YVININDPVMKNKLNQDQKKMMLLFEQFNLITDRVRNIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLML 2745 I++ Q DGGL+ N+I+Q NV + + RD +V+S+ GY A+ G+LWI+ L++A V++ + RK R+ + + G K S Y + + ++ FCL T ++Q+H +IG SA+ + +S+ + + P L ++L +R YLS F N + +TA V+E+I+AT+ MQ +FN L ++GV F G + + V+ S A++ T + L ++ I N L D C C+ + F A + F P +FA + FV +N+T E+V AQ G+ +K + +T++ M ++I ++ +M + W + K ++ ID + + + +V+ K S S + LAV LF+ + +GI L V L+ R S G L+ A+ ML + FL G +E+CRYL Q +V V H+ +T LD HIN FL + P+I ++ P P+P P R+ +Y L CQ++ +L A +AI + +L+ PE++A+F+ +GR+++++SL DP +M P + + L A +L F ++ EE + +P T +++ +E P D D Y + Y + V K + Q ++ L N+ T + + + + VV SL +L K+ ++++K L ++ + F+ I +TP ++A ++ +GPK+M+++G CR ++EA + ++ C +V +N W G + L+ T ++SI L+L Sbjct: 11 IISYTQPSLDGGLLAYAFNNIVQLPTAKQANVSFYSPKHTVRD---HVLSTYARTGYAVAVTSGLLWIILLLTAAVFLCF--------QCRRKARRKTAMVYLTDMTSGVMEANMPMLVMDAAPKRSSKPFYKRREQLQSHWSCLAIQFFLFCLLTVLLGTGVLLGFTVSSQLHANLASPPTHEEAIGRLLTSAELEHVDSSK--SHVFPRLLRALAQVRAYLSEFVQNTKNHTAPAVEELIRATEQMQDGMTNEFNALLFDKIGVSEAFAQGDLLGSSVISLITHSMAVVEQDTSVKAHFERF-------KIELQTWLRLINNYGPSLTDGNCTGQCRWLHDTFAGNLTARPDSFMPPFTFAIALKFVTTDRNQTAETVQAQLNQGKILADKQLIETKKIMAERINIPKSIGDMIDQRWDMLGSQLGKAIQAIDQAALMV-TRSVAPKVSSGSTIALAVGCIFWSLFLLLTVGITWLLIHYHCVPGKLNRHDRHRVRSVASCG----LVLFAISMLFAVILFLSAGYAYSEVCRYLDPGQKMVTVVRHDTLKGTYTSETVFTLDSHINEFLNQHWPEIEAIALRATPPGSKPMPIPHIRSPVYALTHNCQQDMGVLQAFDAIRDFNMTSLNDPEMSARFVNIGREIMMDSLRSIDPNEMFPAETDEQLAMAGRLDDF-IVNFEELRQNLPTT--YVSVRGTEEDSVNYRPYPEKAMWDAWDAYRTIIYPSLTTEQVQKIEFATQQVRLGLTQMAANIKT--IDGHLTELSKAKKVSHVVVSLQANLAKLKSLMSDKPRLLEVAVKLFEENIAANTPDEAAKLVVTYGPKLMAEVGRCRRLYEATRDVTESVCGGVVTVMNGVWFVAGWITLVGT-VISIFGLLL 864
BLAST of Prominin (Prom) protein, putative vs. TrEMBL
Match: H2KNI2 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CLF_100222 PE=4 SV=1) HSP 1 Score: 254.603 bits (649), Expect = 1.139e-66 Identity = 223/882 (25.28%), Postives = 396/882 (44.90%), Query Frame = 1 Query: 346 ILNNAQTVHDGGLINSILQNVQIL---NNSNV-----KRDIMPYVVSSRMTGGYVAALFFGILWILALISAMVYMFYLYFKRPNSNTNRKPIRRQFLAVRSFFAKG--------------DKNSFSFVYSXXXXXXXXXXXXXXXXXCFCL-------------TNANQIHRSIGE-------------SAQSYNANSTAKPNAILPALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQELYPRVMNPTFRLFDFIGEIRNSFKQLPD--CDEGCKQF-EAFFNQPFAEVEGF-PETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAV------LFVPIFLGIVVLFFAL-SVATSLHVWPEKRPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQPIV--VTHN--------DTRLVLDEHINRFLQVNLPKIA----KSMPKSEFPLPKP--RNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKE------PMAITTFMDNVDKYIS-HYVININDPVMKNKLNQDQKKMMLLFEQFNLITDRVRNIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLML 2745 I++ Q DGGL+ L N+ L +NV K + +V+S+ GY A+ G+LWI+ L++A V++ + RK R+ + + G K S Y + + ++ FCL T ++Q+H S+ SA+ + +S+ + + P L ++L +R YLS F N + +TA V+E+I+AT+ MQ +FN L ++GV F G + + V+ S A++ T + L ++ I N L D C + C + F A + F P +FA + FV +N+T E+V AQ G+ +K + +T++ M ++I ++ +M E W + K ++ ID + + + +V+ K S S + LAV LF+ + +GI L V + L+ R S G L+ A+ M + FL G +E+CRYL Q +V V H+ +T LD HIN FL + P+I ++ P P+P P R+ +Y + C++N +L A +AI + +L+ PE++A+F+ +GR+++++SL DP +M P + + L A +L F ++ EE + +P T +++ +E P D D Y + Y + V K + Q ++ L N+ T + +++ + VV SL +L K+ ++++K L +I + F+ I TP ++A ++ +GPK+M+++G CR ++EA + ++ C +V +N W G + L+ T ++SI L+L Sbjct: 11 IISYTQPSLDGGLLAYALNNIVQLPTAKQANVSFYSPKHTVRDHVLSTYARTGYAVAVTSGLLWIILLLTAAVFLCF--------QCRRKARRKTGMVYLADMTSGVMEANMPMLVMDAAPKRSSKPFYKRREQLQSHWSCLAVQFFLFCLLTVLLGTGVLLGFTVSSQLHASLASPPTHEEAIGRLLTSAELEHVDSSK--SHVFPRLLRALAQVRAYLSEFVQNTKNHTAPVVEELIRATERMQDGMTNEFNALLFDKIGVSEAFAQGDLLGSSVISLITHSMAVVEQDTSVKAHFERF-------KIELQTWLRLINNYGPSLTDGNCTDQCHLLHDTFTGNLTARPDSFMPPFTFAIALKFVTTDRNQTAETVQAQLNQGKILADKQLTETKKIMAERINIPKSIGDMIDERWDMLGPQLGKAIQAIDQAALMV-TRSVAPKVSSGSTIALAVGCIFWSLFLLLTVGITWLLIHYHCVPSKLNRHDRHRVRSVASCG----LVLFAISMSFAVILFLSAGYAYSEVCRYLDPGQKMVTVVRHDTLKGTYTSETVFPLDSHINEFLNQHWPEIEAIALRAAPAGNKPMPLPHIRSPIYAVTHNCRQNMGVLQAFDAIRDFNMTSLNDPEMSARFVNIGREIMMDSLRSIDPNEMFPAETDEQLAMAGRLDDF-IVNFEELRQNLPTT--YVSVRGTEEDSVNYRPYPEKAMWDAWDAYRTIIYPSLTAEQVQKIEFATQQVRLGLTQMAANIKT--IDGHLTDLSKAKKVGHVVVSLQANLAKLKSLMSDKPRLLEIAVKLFEENIAAKTPDEAAKLVVTYGPKLMAEVGRCRRLYEATRDVTESACGGVVTVMNGVWFVAGWITLVGT-VISIFGLLL 864
BLAST of Prominin (Prom) protein, putative vs. TrEMBL
Match: A0A419PG13 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CSKR_671s PE=4 SV=1) HSP 1 Score: 253.447 bits (646), Expect = 3.310e-66 Identity = 223/882 (25.28%), Postives = 395/882 (44.78%), Query Frame = 1 Query: 346 ILNNAQTVHDGGLINSILQNVQIL---NNSNV-----KRDIMPYVVSSRMTGGYVAALFFGILWILALISAMVYMFYLYFKRPNSNTNRKPIRRQFLAVRSFFAKG--------------DKNSFSFVYSXXXXXXXXXXXXXXXXXCFCL-------------TNANQIHRSIGE-------------SAQSYNANSTAKPNAILPALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQELYPRVMNPTFRLFDFIGEIRNSFKQLPD--CDEGCKQF-EAFFNQPFAEVEGF-PETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAV------LFVPIFLGIVVLFFAL-SVATSLHVWPEKRPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQPIV--VTHN--------DTRLVLDEHINRFLQVNLPKIA----KSMPKSEFPLPKP--RNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKE------PMAITTFMDNVDKYIS-HYVININDPVMKNKLNQDQKKMMLLFEQFNLITDRVRNIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLML 2745 I++ Q DGGL+ L N+ L +NV K + +V+S+ GY A+ G+LWI+ L++A V++ + RK R+ + + G K S Y + + ++ FCL T ++Q+H S+ SA+ + +S+ + + P L ++L +R YLS F N + +TA V+E+I+AT+ MQ +FN L ++GV F G + + V+ S A++ T + L ++ I N L D C C + F A + F P +FA + FV +N+T E+V AQ G+ +K + +T++ M ++I ++ +M E W + K ++ ID + + + +V+ K S S + LAV LF+ + +GI L V + L+ R S G L+ A+ M + FL G +E+CRYL Q +V V H+ +T LD HIN FL + P+I ++ P P+P P R+ +Y + C++N +L A +AI + +L+ PE++A+F+ +GR+++++SL DP +M P + + L A +L F ++ EE + +P T +++ +E P D D Y + Y + V K + Q ++ L N+ T + +++ + VV SL +L K+ ++++K L +I + F+ I TP ++A ++ +GPK+M+++G CR ++EA + ++ C +V +N W G + L+ T ++SI L+L Sbjct: 11 IISYTQPSLDGGLLAYALNNIVQLPTAKQANVSFYSPKHTVRDHVLSTYARTGYAVAVTSGLLWIILLLTAAVFLCF--------QCRRKARRKTGMVYLADMTSGVMEANMPMLVMDAAPKRSSKPFYKRREQLQSHWSCLAVQFFLFCLLTVLLGTGVLLGFTVSSQLHASLASPPTHEEAIGRLLTSAELEHVDSSK--SHVFPRLLRALAQVRAYLSEFVQNTKNHTAPVVEELIRATERMQDGMTNEFNALLFDKIGVSEAFAQGDLLGSSVISLITHSMAVVEQDTSVKAHFERF-------KIELQTWLRLINNYGPSLTDGNCTGQCHLLHDTFTGNLTARPDSFMPPFTFAIALKFVTTDRNQTAETVQAQLNQGKILADKQLTETKKIMAERINIPKSIGDMIDERWDMLGPQLGKAIQAIDQAALMV-TRSVAPKVSSGSTIALAVGCIFWSLFLLLTVGITWLLIHYHCVPSKLNRHDRHRVRSVASCG----LVLFAISMSFAVILFLSAGYAYSEVCRYLDPGQKMVTVVRHDTLKGTYTSETVFPLDSHINEFLNQHWPEIEAIALRAAPAGNKPMPLPHIRSPIYAVTHNCRQNMGVLQAFDAIRDFNMTSLNDPEMSARFVNIGREIMMDSLRSIDPNEMFPAETDEQLAMAGRLDDF-IVNFEELRQNLPTT--YVSVRGTEEDSVNYRPYPEKAMWDAWDAYRTIIYPSLTAEQVQKIEFATQQVRLGLTQMAANIKT--IDGHLTDLSKAKKVGHVVVSLQANLAKLKSLMSDKPRLLEIAVKLFEENIAAKTPDEAAKLVVTYGPKLMAEVGRCRRLYEATRDVTESACGGVVTVMNGVWFVAGWITLVGT-VISIFGLLL 864
BLAST of Prominin (Prom) protein, putative vs. Ensembl Sea Lamprey
Match: prom1b (prominin 1 b [Source:ZFIN;Acc:ZDB-GENE-031003-1]) HSP 1 Score: 51.9878 bits (123), Expect = 9.096e-7 Identity = 87/384 (22.66%), Postives = 148/384 (38.54%), Query Frame = 1 Query: 1654 SALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQPIVVTHNDTRLVLDEHINRFLQV-NLPKIAKSMPKSEFPLPKPRNVLYGLIKKCQKNEPILAAINA-----IESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAID----TEESIRKVPRTPIFI-------TTNNGKEPMAITTFMDNVDKYIS--HY----VININDPVMKNKLNQDQKKMMLLFEQFNLITDRVRNIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVF 2736 +A+ G+ S IF L+MLV T TF+ GG VE C+ L D+++ +F NL K +P F P + G+ C+ N+ I +A ++SL ++ +KF + L K+L P +K SL + G+ K ID T E + + + + + NN + A+ + I HY ++N + + LN Q+ + L + + D++ +SL + +II KT + I YF++ + KF + +K+ C+P+ S C ++ LNA+W LG + L I SI+F Sbjct: 482 NAVSSGVAFSFIFSWLLMLVVTFTFVLGGNVEKLFCQALA----------------DKNLFKFFDTPNLFKPKHLLPGVLFNKPDLNMTIEGVYSDCKMNKGIYSAFQLSNLFNLDSLLNMTQYTNDITSKFDPINANL--------SDMKLLEPSVKQSLLDFATTGIDK-IDFSAFTAELNKGITKVDLLLFADELSEKANNLPQSGALANALRGHAASIRWIHYNQVVLLNSSMSTLNKSLNSLQRTSLALQSEITEVIDKL--------------DTAQSLINNNASQVIIGETKTYMKTIIG-YFESYVT----------WTKF--SISNKVATCKPVSNLVDSVDIIACSYVMDSLNAFWFGLGWATVFL--IPSIIF 811
BLAST of Prominin (Prom) protein, putative vs. Planmine SMEST
Match: SMESG000010133.1 (SMESG000010133.1) HSP 1 Score: 1682.92 bits (4357), Expect = 0.000e+0 Identity = 833/843 (98.81%), Postives = 838/843 (99.41%), Query Frame = 1 Query: 325 MESFANIILNNAQTVHDGGLINSILQNVQILNNSNVKRDIMPYVVSSRMTGGYVAALFFGILWILALISAMVYMFYLYFKRPNSNTNRKPIRRQFLAVRSFFAKGDKNSFSFVYSXXXXXXXXXXXXXXXXXCFCLTNANQIHRSIGESAQSYNANSTAKPNAILPALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQELYPRVMNPTFRLFDFIGEIRNSFKQLPDCDEGCKQFEAFFNQPFAEVEGFPETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAVLFVPIFLGIVVLFFALSVATSLHVWPEKRPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQPIVVTHNDTRLVLDEHINRFLQVNLPKIAKSMPKSEFPLPKPRNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKEPMAITTFMDNVDKYISHYVININDPVMKNKLNQDQKKMMLLFEQFNLITDRVRNIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLMLNSSGQDSSLPYEADKEKEANVAKSLIKENELESTKV 2853 MESFANIILNNAQTVHDGGLINSILQNVQILNNSNVKRDIMPYVVSSRMTGGYVAALFFGILWILALISAMVYMFYLYFKRPNSNTNRKPIRRQFL V++FFAKGDKNSFSFVYSFQIVVIVIF+IPIFLLLCFCLTNANQI SIGESAQSYNANSTAKPNAILPALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQELYPRVMNPTFRLFDFIGEIRNSFKQLPDCDEGCKQFE FFNQPFAEVEGFPETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAVLFVPIFLGIVVLFFALSVATSLHVWPEKRPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQP VVTHNDTRLVLDEHINRFLQVNLPKIAKSMPKSEFPLPKPRNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKEPMAITTFMDNVDKYISHYVI+INDPVMKNKLNQDQKKMMLLFEQFNLITDRV+NIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLMLNSSGQDSSLPYEADKEKEANVAKSLIKENELESTKV Sbjct: 1 MESFANIILNNAQTVHDGGLINSILQNVQILNNSNVKRDIMPYVVSSRMTGGYVAALFFGILWILALISAMVYMFYLYFKRPNSNTNRKPIRRQFLPVKNFFAKGDKNSFSFVYSFQIVVIVIFSIPIFLLLCFCLTNANQIRHSIGESAQSYNANSTAKPNAILPALKKSLYHIRNYLSTFADNARQNTASTVDEIIQATKDMQKETQKDFNKKLMTRLGVENTFKYGQEMTNIVVKFYDISNALLNNQTQYNGVIQELYPRVMNPTFRLFDFIGEIRNSFKQLPDCDEGCKQFETFFNQPFAEVEGFPETSFATSFLFVMKQQNKTRESVIAQTQHGRKEMNKTMAKTEEKMKRLLDIDGTVRNMTGETWTKMEMNFVKIVELIDNITMKLNSDNVSNKASRYSGLLLAVLFVPIFLGIVVLFFALSVATSLHVWPEKRPHSALQIGMYLSLIFLALIMLVCTLTFLYGGKVETELCRYLRTNQPKVVTHNDTRLVLDEHINRFLQVNLPKIAKSMPKSEFPLPKPRNVLYGLIKKCQKNEPILAAINAIESLDTAALSKPEVAAKFIRVGRQLLIESLNETDPKKMLPPDMKDSLQQASQLGMFKAIDTEESIRKVPRTPIFITTNNGKEPMAITTFMDNVDKYISHYVISINDPVMKNKLNQDQKKMMLLFEQFNLITDRVKNIFSNMKYIPSIKPVVKSLSESLDKMLIILNNKTELFKIGNEYFDNIIVKSTPQKSAGIMAKFGPKMMSKLGHCRPIFEAYQSSIDTTCDIIVMKLNAYWLYLGAVGLLLTCILSIVFLMLNSSGQDSSLPYEADKEKEANVAKSLIKENELESTKV 843 The following BLAST results are available for this feature:
BLAST of Prominin (Prom) protein, putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Prominin (Prom) protein, putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Prominin (Prom) protein, putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of Prominin (Prom) protein, putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030797 ID=SMED30030797|Name=Prominin (Prom) protein, putative|organism=Schmidtea mediterranea sexual|type=transcript|length=3485bpback to top protein sequence of SMED30030797-orf-1 >SMED30030797-orf-1 ID=SMED30030797-orf-1|Name=SMED30030797-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=844bp MESFANIILNNAQTVHDGGLINSILQNVQILNNSNVKRDIMPYVVSSRMTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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