Gonadotropin-releasing hormone receptor

Overview
NameGonadotropin-releasing hormone receptor
Smed IDSMED30030787
Length (bp)1242
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Gonadotropin-releasing hormone receptor (SMED30030787) t-SNE clustered cells

Violin plots show distribution of expression levels for Gonadotropin-releasing hormone receptor (SMED30030787) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Gonadotropin-releasing hormone receptor (SMED30030787) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Gonadotropin-releasing hormone receptor (SMED30030787) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30030787

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30030787h1SMcG0010558 dd_Smed_v6_75337_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: GNRHR (gonadotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4421])

HSP 1 Score: 103.605 bits (257), Expect = 3.132e-24
Identity = 94/353 (26.63%), Postives = 165/353 (46.74%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG-----FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL-SDKMVVICLITV-WSLSTIFSIPQMKLNKVL----LGPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            +P   L  KI+VT+    F++S   N     FLLK ++ T +  KG        L+ HL +A+L  T++ +  + +WN+T QWY GE+LCK++ + +  S  +  +++  I +DR   I R   L S+  V   ++ + W LS++F+ PQ+ + +++         K F QC  +     +     Y F      F++PL ++L C                K+ F L+ +L Q                             +P++  L QSK   + RA+ K+L ++ +   ++    TPY++      LG+   FD  ++N   D ++H+FF  + LN  F+P+IYGYF+
Sbjct:   28 LPTLTLSGKIRVTVTFFLFLLSATFNAS---FLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICN--------------AKIIFTLTRVLHQ-----------------------------DPHELQLNQSKNN-IPRARLKTLKMTVAFATSFTVCWTPYYV------LGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFS 327          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: AVPR1B (arginine vasopressin receptor 1B [Source:HGNC Symbol;Acc:HGNC:896])

HSP 1 Score: 82.4185 bits (202), Expect = 1.748e-16
Identity = 77/341 (22.58%), Postives = 165/341 (48.39%), Query Frame = 1
Query:   64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI----LNSAFNPIIYGYFNN 1056
            +K+++ +L T  +++  GN+  L+ L +  R+ S+     +  +LHL + DL+V +  +L + +W++T ++ G ++LC+ +K+ + LS  +STY++  + +DR   +   +RS +   +   + +   W L+ IFS+PQ+    L +V+ G    + +     +       R Y     +  F+LP+ ++  CY  I   I K  + +   ++ +     +     +  TL+ + + GL  + +                    +SRAK +++ ++  I++ Y+    P+   + +Q   V+D   N+  ++ ++  F +S+    LNS  NP IY  FN+
Sbjct:   34 AKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSR----MHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWA----DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLK-VKTQAWRVGGGGWRTWDRPSPSTLAATTR-GLPSRVSSINT----------------ISRAKIRTVKMTFVIVLAYIACWAPF---FSVQMWSVWDK--NAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNS 343          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: GNRHR (gonadotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4421])

HSP 1 Score: 78.9518 bits (193), Expect = 4.138e-16
Identity = 54/170 (31.76%), Postives = 91/170 (53.53%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFN----KLIL-HLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL-SDKMVVICLIT-VWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRN 531
            +P   L  KI+VT+    F++S   N     FLLK ++ T +  KG      KL+L HL +A+L  T++ +  + +WN+T QWY GE+LCK++ + +  S  +  +++  I +DR   I R   L S+  V   ++   W LS++F+ PQ+ L+      +     QC+N
Sbjct:   28 LPTLTLSGKIRVTVTFFLFLLSATFNAS---FLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHH---PSFHHADLQCKN 191          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: NPSR1 (neuropeptide S receptor 1 [Source:HGNC Symbol;Acc:HGNC:23631])

HSP 1 Score: 77.0258 bits (188), Expect = 7.093e-15
Identity = 80/358 (22.35%), Postives = 159/358 (44.41%), Query Frame = 1
Query:   85 LLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV----ETRVYPFVCII--LAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI-------LNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQ 1113
            L   F+ ++VGN V L    +R++++  +F      +  L I D    ++ +LT+  W  T  +   +++C+++++ + +   +STY++ ++ IDR   I+   +    +K   + ++  WSLS +FSIP +    ++ G  K+      N E++ +     ++   P++ I+  L + +PL +I   YG ++ TI  +                   S +    +S      L    N                 R  +S+AK K++  S  II+ ++   +PY++         FD + N  L   +   F+ S+       LNSA NP+IY  F++    P R ++ Q  ++ F+
Sbjct:   56 LWVLFVFTIVGNSVVLFSTWRRKKKSRMTF-----FVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTL----IIFG--KRTL---SNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIK-------------------SKTYETVISNCSDGKLCSSYN-----------------RGLISKAKIKAIKYSIIIILAFICCWSPYFL---------FDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFR 354          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: NPSR1 (neuropeptide S receptor 1 [Source:HGNC Symbol;Acc:HGNC:23631])

HSP 1 Score: 73.1738 bits (178), Expect = 1.510e-13
Identity = 78/352 (22.16%), Postives = 156/352 (44.32%), Query Frame = 1
Query:   85 LLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV----ETRVYPFVCII--LAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI-------LNSAFNPIIYGYFNNLWFLPPRIRKYQK 1095
            L   F+ ++VGN V L    +R++++  +F      +  L I D    ++ +LT+  W  T  +   +++C+++++ + +   +STY++ ++ IDR   I+   +    +K   + ++  WSLS +FSIP +    ++ G  K+      N E++ +     ++   P++ I+  L + +PL +I   YG ++ TI  +                   S +    +S      L    N                 R  +S+AK K++  S  II+ ++   +PY++         FD + N  L   +   F+ S+       LNSA NP+IY  F++    P R+ + ++
Sbjct:   56 LWVLFVFTIVGNSVVLFSTWRRKKKSRMTF-----FVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTL----IIFG--KRTL---SNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIK-------------------SKTYETVISNCSDGKLCSSYN-----------------RGLISKAKIKAIKYSIIIILAFICCWSPYFL---------FDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCRVIRLRQ 348          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: gnrr-1 (GoNadotropin-Releasing hormone Receptor (GnRHR) related [Source:UniProtKB/TrEMBL;Acc:H1ZUW9])

HSP 1 Score: 88.5817 bits (218), Expect = 4.728e-19
Identity = 83/331 (25.08%), Postives = 155/331 (46.83%), Query Frame = 1
Query:   88 LTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRV---YPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            L  FI++ VGN+   +FL+  R Q  +  +  + L+LH+ IA L VT++ +  E + N    W+ G+V+C++ KF    +   S  ++  I +DR   I      +R+R+   +MV       W++S + S PQ+ L K    P    + QC +      +   V   +  V II  ++ PL V + CY  I+  I ++ +++G                               EKE++     + ++  L ++ +  L +AK ++L ++  I++ ++   TPY ++ FL  L   D I      ++  + +  ++LNSA +P +YGYF+
Sbjct:   28 LALFILAFVGNVT--MFLILCRNQLVK-VRRVHSLLLHMNIAHLLVTLVVMPKEILHNYMVAWFAGDVMCRICKFFDVFAISLSMNVLICITLDRFYSIFFPLYAMRARKSVQRMVSF----AWTISFVTSAPQLYLFKTATHPCFDWYTQCVSKNFIGELSNDVVFFFSIVNIIQVYIAPLFVTVVCYSLILWRISRKSKLVG-------------------------------EKESE-----KSSELLLRRNGQNNLEKAKSRTLKMTFVIVLAFIFCWTPYSILMFLHFLRHTDWIPK----DIRKFIYAFAVLNSAISPYLYGYFS 311          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: gnrr-1 (GoNadotropin-Releasing hormone Receptor (GnRHR) related [Source:UniProtKB/TrEMBL;Acc:H1ZUW9])

HSP 1 Score: 88.5817 bits (218), Expect = 5.064e-19
Identity = 83/331 (25.08%), Postives = 155/331 (46.83%), Query Frame = 1
Query:   88 LTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRV---YPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            L  FI++ VGN+   +FL+  R Q  +  +  + L+LH+ IA L VT++ +  E + N    W+ G+V+C++ KF    +   S  ++  I +DR   I      +R+R+   +MV       W++S + S PQ+ L K    P    + QC +      +   V   +  V II  ++ PL V + CY  I+  I ++ +++G                               EKE++     + ++  L ++ +  L +AK ++L ++  I++ ++   TPY ++ FL  L   D I      ++  + +  ++LNSA +P +YGYF+
Sbjct:   28 LALFILAFVGNVT--MFLILCRNQLVK-VRRVHSLLLHMNIAHLLVTLVVMPKEILHNYMVAWFAGDVMCRICKFFDVFAISLSMNVLICITLDRFYSIFFPLYAMRARKSVQRMVSF----AWTISFVTSAPQLYLFKTATHPCFDWYTQCVSKNFIGELSNDVVFFFSIVNIIQVYIAPLFVTVVCYSLILWRISRKSKLVG-------------------------------EKESE-----KSSELLLRRNGQNNLEKAKSRTLKMTFVIVLAFIFCWTPYSILMFLHFLRHTDWIPK----DIRKFIYAFAVLNSAISPYLYGYFS 311          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: gnrr-5 (GoNadotropin-Releasing hormone Receptor (GnRHR) related [Source:UniProtKB/TrEMBL;Acc:O44536])

HSP 1 Score: 69.707 bits (169), Expect = 1.051e-12
Identity = 55/175 (31.43%), Postives = 89/175 (50.86%), Query Frame = 1
Query:   67 KIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLIL---HLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRV--QVIIRSRRLSDKMVVIC---LITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRV 564
            +IK+ + + + IV  +G  + L+ L +  R  S++ K  ++++L    L +ADL    L++  + IW +T QWYGGE LC+   F    SF  ++++IA I IDRV     I S     K  + C   L   W L+ + S+PQ  +      P++  +F QC  I M    E R+
Sbjct:   30 RIKIEVCI-YVIVFFIGGPLNLMALSRSLRAFSRTHKAKSQILLLRITLNLADLMTLFLYVPKQIIWLITYQWYGGEFLCRACAFFSTFSFYLNSFVIACIAIDRVFGAYNISSLNAHRKAYIRCRNLLGCGWVLAFLLSLPQAVVFTT-TSPYENIDFKQCATIFMIFLHEKRI 202          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8])

HSP 1 Score: 69.3218 bits (168), Expect = 1.209e-12
Identity = 54/208 (25.96%), Postives = 99/208 (47.60%), Query Frame = 1
Query:   37 DPMPNFDLHSKIKVT---ILLTFFIVSVVGNIVTLIFLLKRRR-QTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIP---QMKLNKV--LLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCY 627
            D  P+      + VT   + L  F++ ++GN   L   +K R+ QT Q     N  IL+LC +++ + +  L    I N+  QW+    +CKLI   +  S   ST+ ++ I +DR  +++R   ++LS +  ++  + +W +S +  +P    M + K+  L G +  E +    +        + Y F+ +I  FL P A +  CY
Sbjct:   14 DKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQ-----NIFILNLCASNVLMCLTSLPITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRYNLVVRPHKQKLSSRSAMMIALLIWVISVVVCMPYGWYMDVEKLNGLCGEYCSEHWPLAEVR-------KGYTFLVLITQFLFPFATMAFCY 209          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8])

HSP 1 Score: 68.9366 bits (167), Expect = 1.503e-12
Identity = 54/208 (25.96%), Postives = 99/208 (47.60%), Query Frame = 1
Query:   37 DPMPNFDLHSKIKVT---ILLTFFIVSVVGNIVTLIFLLKRRR-QTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIP---QMKLNKV--LLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCY 627
            D  P+      + VT   + L  F++ ++GN   L   +K R+ QT Q     N  IL+LC +++ + +  L    I N+  QW+    +CKLI   +  S   ST+ ++ I +DR  +++R   ++LS +  ++  + +W +S +  +P    M + K+  L G +  E +    +        + Y F+ +I  FL P A +  CY
Sbjct:   39 DKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQ-----NIFILNLCASNVLMCLTSLPITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRYNLVVRPHKQKLSSRSAMMIALLIWVISVVVCMPYGWYMDVEKLNGLCGEYCSEHWPLAEVR-------KGYTFLVLITQFLFPFATMAFCY 234          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: CrzR (gene:FBgn0036278 transcript:FBtr0075989)

HSP 1 Score: 110.538 bits (275), Expect = 6.433e-26
Identity = 100/353 (28.33%), Postives = 163/353 (46.18%), Query Frame = 1
Query:   37 DPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK---RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDR---VQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV-ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYW--MVYFL-----QHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            D  P       +KV +L    + S++GN++T+  + K    RR +  ++     L+ HL IAD+ VT   ++ E  W  T QW   E+ CKL+K  +  S   STY++  IG+DR   V+  ++S  ++ +   + L   + LS + S+PQ  +  V  GP+ +EFYQC      +   + ++Y    ++  FLLPL ++ G Y                               ST +T+S+SEK     K   +     P +     +++  + +AK KSL IS  III +L   TPY+  M+ F+     + LG          D+L    F+  + NS  NP+IYG F+
Sbjct:  109 DHAPQLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCHRL-LGGTYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTADWQEQMYATFTLVFTFLLPLCILFGTY------------------------------MSTFRTISSSEKMFQGSKLANYSTAKLPTQT----NRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMMIMFMFLNPDKRLG----------DDLQDAIFFFGMSNSLVNPLIYGAFH 416          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: CrzR (gene:FBgn0036278 transcript:FBtr0330069)

HSP 1 Score: 110.153 bits (274), Expect = 9.039e-26
Identity = 100/353 (28.33%), Postives = 163/353 (46.18%), Query Frame = 1
Query:   37 DPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK---RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDR---VQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV-ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYW--MVYFL-----QHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            D  P       +KV +L    + S++GN++T+  + K    RR +  ++     L+ HL IAD+ VT   ++ E  W  T QW   E+ CKL+K  +  S   STY++  IG+DR   V+  ++S  ++ +   + L   + LS + S+PQ  +  V  GP+ +EFYQC      +   + ++Y    ++  FLLPL ++ G Y                               ST +T+S+SEK     K   +     P +     +++  + +AK KSL IS  III +L   TPY+  M+ F+     + LG          D+L    F+  + NS  NP+IYG F+
Sbjct:  109 DHAPQLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCHRL-LGGTYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTADWQEQMYATFTLVFTFLLPLCILFGTY------------------------------MSTFRTISSSEKMFQGSKLANYSTAKLPTQT----NRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMMIMFMFLNPDKRLG----------DDLQDAIFFFGMSNSLVNPLIYGAFH 416          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: AkhR (gene:FBgn0025595 transcript:FBtr0332331)

HSP 1 Score: 95.9005 bits (237), Expect = 2.488e-21
Identity = 65/241 (26.97%), Postives = 115/241 (47.72%), Query Frame = 1
Query:   52 FDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG---FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGL 762
            F+   ++ +T+    F++S +GN   L  L KRR       +G    + +++HL IADL VT+L +  E +W  T QW   +++C+L+ F R      S+Y++  I +DR   I++  + S     I L   W  S + SIPQ  L  +   P    ++QC      +S  + ++Y    +   +  PL + + CYG I + I ++ Q +      L  ++ +    S +  LS ++K  L
Sbjct:   34 FNDGHRLSITVYSILFVISTIGNSTVLYLLTKRR------LRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRV------LKDVIAERFRRSNDDVLSRAKKRTL 262          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: AkhR (gene:FBgn0025595 transcript:FBtr0079309)

HSP 1 Score: 95.9005 bits (237), Expect = 2.488e-21
Identity = 65/241 (26.97%), Postives = 115/241 (47.72%), Query Frame = 1
Query:   52 FDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG---FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGL 762
            F+   ++ +T+    F++S +GN   L  L KRR       +G    + +++HL IADL VT+L +  E +W  T QW   +++C+L+ F R      S+Y++  I +DR   I++  + S     I L   W  S + SIPQ  L  +   P    ++QC      +S  + ++Y    +   +  PL + + CYG I + I ++ Q +      L  ++ +    S +  LS ++K  L
Sbjct:   34 FNDGHRLSITVYSILFVISTIGNSTVLYLLTKRR------LRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRV------LKDVIAERFRRSNDDVLSRAKKRTL 262          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: AkhR (gene:FBgn0025595 transcript:FBtr0079308)

HSP 1 Score: 95.9005 bits (237), Expect = 2.488e-21
Identity = 65/241 (26.97%), Postives = 115/241 (47.72%), Query Frame = 1
Query:   52 FDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG---FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGL 762
            F+   ++ +T+    F++S +GN   L  L KRR       +G    + +++HL IADL VT+L +  E +W  T QW   +++C+L+ F R      S+Y++  I +DR   I++  + S     I L   W  S + SIPQ  L  +   P    ++QC      +S  + ++Y    +   +  PL + + CYG I + I ++ Q +      L  ++ +    S +  LS ++K  L
Sbjct:   34 FNDGHRLSITVYSILFVISTIGNSTVLYLLTKRR------LRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRV------LKDVIAERFRRSNDDVLSRAKKRTL 262          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr4 (gonadotropin releasing hormone receptor 4 [Source:ZFIN;Acc:ZDB-GENE-050419-76])

HSP 1 Score: 97.4413 bits (241), Expect = 8.902e-22
Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F + +K++V I  T   VS V N+  L       ++ S        LI++L +ADL VT + +  +  WN+T QW  G++ C+L+ F + ++  S  ++   I +DR   I+   +   + K   I L   W++S + S+PQM L   +       F QC  R   +K + ET   ++ F+C+   FL+PLA+++ CY  I++ I ++    G +S                                        +KE   +   + + +A+ ++L +S  I+ +++   TPY+++   Y+     + +T+ +S    L+H  F   + N+  +PI YG F
Sbjct:   41 LPTFSMAAKVRVIITFTLCAVSAVCNLGVLWAASTNNKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWLAGDLACRLLMFLKLVAMYSCAFVTVVISLDRQSAILNPLAINKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTITVPANFTQCTTRGSFVKHWQETIYNMFTFICL---FLIPLAIMICCYTRILVEISRRMTK-GNIS----------------------------------------SKEVHLRRSHSNIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLPEDLEETVSHS----LTHMLFIFGLFNAILDPITYGLF 333          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr4 (gonadotropin releasing hormone receptor 4 [Source:ZFIN;Acc:ZDB-GENE-050419-76])

HSP 1 Score: 97.4413 bits (241), Expect = 8.902e-22
Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F + +K++V I  T   VS V N+  L       ++ S        LI++L +ADL VT + +  +  WN+T QW  G++ C+L+ F + ++  S  ++   I +DR   I+   +   + K   I L   W++S + S+PQM L   +       F QC  R   +K + ET   ++ F+C+   FL+PLA+++ CY  I++ I ++    G +S                                        +KE   +   + + +A+ ++L +S  I+ +++   TPY+++   Y+     + +T+ +S    L+H  F   + N+  +PI YG F
Sbjct:   41 LPTFSMAAKVRVIITFTLCAVSAVCNLGVLWAASTNNKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWLAGDLACRLLMFLKLVAMYSCAFVTVVISLDRQSAILNPLAINKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTITVPANFTQCTTRGSFVKHWQETIYNMFTFICL---FLIPLAIMICCYTRILVEISRRMTK-GNIS----------------------------------------SKEVHLRRSHSNIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLPEDLEETVSHS----LTHMLFIFGLFNAILDPITYGLF 333          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr4 (gonadotropin releasing hormone receptor 4 [Source:ZFIN;Acc:ZDB-GENE-050419-76])

HSP 1 Score: 97.4413 bits (241), Expect = 8.902e-22
Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F + +K++V I  T   VS V N+  L       ++ S        LI++L +ADL VT + +  +  WN+T QW  G++ C+L+ F + ++  S  ++   I +DR   I+   +   + K   I L   W++S + S+PQM L   +       F QC  R   +K + ET   ++ F+C+   FL+PLA+++ CY  I++ I ++    G +S                                        +KE   +   + + +A+ ++L +S  I+ +++   TPY+++   Y+     + +T+ +S    L+H  F   + N+  +PI YG F
Sbjct:   41 LPTFSMAAKVRVIITFTLCAVSAVCNLGVLWAASTNNKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWLAGDLACRLLMFLKLVAMYSCAFVTVVISLDRQSAILNPLAINKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTITVPANFTQCTTRGSFVKHWQETIYNMFTFICL---FLIPLAIMICCYTRILVEISRRMTK-GNIS----------------------------------------SKEVHLRRSHSNIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLPEDLEETVSHS----LTHMLFIFGLFNAILDPITYGLF 333          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: avpr1ab (arginine vasopressin receptor 1Ab [Source:ZFIN;Acc:ZDB-GENE-041210-105])

HSP 1 Score: 94.7449 bits (234), Expect = 6.552e-21
Identity = 89/357 (24.93%), Postives = 166/357 (46.50%), Query Frame = 1
Query:   25 NYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQ---MKLNKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI----LNSAFNPIIYGYFNN 1056
            N +TDP    +  +K+++T+L   F+V+VVGN+  L+ +   ++++S+     +  I HL +ADL V    +L +  W +T ++YG + LC+++K  + L   +STY++  + +DR   I   +++ +   +   I + + W  S + S PQ     L+++  G    + Y C       F+E    R Y     +  FL+P+ +++ CYGFI  +I K ++                    T +  + + K+G+  K +               S    +SRAK +++ ++  I++ Y+    P++ V   Q   V+D   N   D+  +    LS     LNS  NP IY  F+ 
Sbjct:   11 NNTTDPFGRNEDVAKMEITVLSVTFLVAVVGNLCVLLAMHNTKKKSSR----MHLFIKHLSLADLVVAFFQVLPQLCWEITYRFYGPDFLCRIVKHLQVLGMFASTYMMVMMTLDRYIAICHPLKTLQQPTRRAYIMICSTWLCSLLLSTPQYFIFSLSEIQNG---SDVYDC----WGHFIEPWGIRAYITWITVGIFLIPVVILMICYGFICHSIWKNFKC------------------KTKRGAAHNPKSGMIGKAS--------------VSSVTIISRAKLRTVKMTFVIVLAYIVCWAPFFTV---QMWSVWDE--NFSWDDSENAAVTLSALLASLNSCCNPWIYMLFSG 319          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr2 (gonadotropin releasing hormone receptor 2 [Source:ZFIN;Acc:ZDB-GENE-090128-3])

HSP 1 Score: 93.2041 bits (230), Expect = 2.445e-20
Identity = 91/364 (25.00%), Postives = 163/364 (44.78%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVV--ICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQI 1116
            +P F   S+++VT+ L    +S   N+  L      +R+ S        +I +L  ADL VT + + T+ +WN+T QW  G++ C+ + F + ++  S  ++   I +DR   I+    ++  M    + L   W++S + SIPQ+ +  V+     K+F QC       S  +   Y        FLLPL +++ CY  I+  I K+                                  +TE        L  NK  L +SK   + +A+ ++L ++  I+++++   TPY+M+   Y+    G+ +T+  S    LSH  F   +LN+  +PIIYG F        R R+ ++  + F++
Sbjct:   37 LPRFTAASQVRVTLTLVLCALSACCNLAVLYSANNNQRKRSH----VRLIITNLAAADLLVTFVVMPTDAVWNITLQWRAGDLACRTLMFLKLVAMYSCAFVTVVISLDRQAAILNPLSINKAMRRNKVLLGVAWTMSVVLSIPQVFVFHVVEIDSPKQFVQCTTYGSFSSRWQETFYNMFTFTFLFLLPLFIMISCYTRILFEISKK----------------------------------MTEDR------LLSNKVQLRRSKNN-IPKARMRTLKMTVVIVLSFMVCWTPYYMLGLWYWFSPAGLEETVSQS----LSHILFIFGLLNACLDPIIYGLFTVPLCRGMRHRQREQNIVAFEL 351          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: nrg3 (neuregulin 3 [Source:Xenbase;Acc:XB-GENE-984146])

HSP 1 Score: 99.7525 bits (247), Expect = 1.460e-22
Identity = 88/348 (25.29%), Postives = 155/348 (44.54%), Query Frame = 1
Query:   37 DP--MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV---ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            DP   P F L +K++V +   FF+++   N+  L  +  +R ++         LIL L +ADL VT L +  + +WN+  QWY GE+ CK++ FG+  +  S+  ++  I +DR   I+   S   + +   I L T W  S + + PQ+ L ++   P    F QC      SF    +   Y        F+ PL V++ CY  I+  I KQ               M+H                               K  L +SK   +S+A+ K+L ++  I+++++   TPY+++   Y+ Q       ++N   + L+H  F   +L++  +P++YG +
Sbjct:   29 DPWTEPTFTLAAKVRVGVTCCFFLIASFSNVAVLCSISGKRCKSH-----LRVLILSLSVADLLVTFLVMPLDALWNVMVQWYAGELSCKVLNFGKLFAMYSAALVLVVISLDRHWAILYPLSFTSAGQRNRIMLWTAWITSLLLASPQLFLFRLRTAP-GVNFTQCAT--HGSFTQHWQETAYNMFTFCTLFVTPLVVMIVCYTRILWEIGKQ---------------MKH-------------------------------KNELARSKNDLISKARLKTLKMTLVIVVSFMVCWTPYYLLGLWYWFQ-----PEMINQTPEYLNHSLFLFGLLHTCTDPLVYGLY 317          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: ccbe1 (collagen and calcium binding EGF domains 1 [Source:Xenbase;Acc:XB-GENE-920172])

HSP 1 Score: 97.0561 bits (240), Expect = 1.620e-21
Identity = 90/345 (26.09%), Postives = 152/345 (44.06%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDE-----LSHWFFWLSILNSAFNPIIYGYF 1050
            +P F   +K +V I    F +S   N+  +       R+     +    LIL+L  ADL VT + +  + IWN+T QW  G++ C+++ F + LS  S  ++   I IDR   I+    +S+  K   I L   W +S + S+PQ+ L   +     + F QC  R    + + ET VY  V  +  FLLPL +++ CY  I+I I ++                               K  L+ KE     YL  +K          + +A+ ++L +S  I+ +++   TPY++      LG++       ++E     L+H  F   ++N+  +PI YG F
Sbjct:   44 LPTFSPAAKARVIITFVIFALSAFCNLAVVWASTNTSRKKRSHVR---ILILNLTTADLLVTFIVMPLDAIWNITVQWQAGDLACRILMFLKLLSMYSCAFVTVVISIDRQSAILNPLGISEAKKRNKIMLSVAWLMSILLSLPQLFLFHTVTITEPQNFTQCTTRGSFQEHWQET-VYNMVSFVCLFLLPLLIMISCYSRILIEISRRM-----------------------------SKGALSSKE----VYLRRSKN--------NIPKARMRTLKMSIVIVSSFIICWTPYYL------LGLWYWFYPEAMEERVSQSLTHILFIFGLVNACLDPITYGLF 337          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: gnrhr (gonadotropin releasing hormone receptor [Source:NCBI gene;Acc:100135417])

HSP 1 Score: 94.7449 bits (234), Expect = 1.076e-20
Identity = 87/356 (24.44%), Postives = 157/356 (44.10%), Query Frame = 1
Query:   13 VTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKL-DELSHWFFWLSILNSAFNPIIYGYFN 1053
            +T+ N     +P F   +KI+V I    F+ S   N+  L  +  + R+ S        LI++L  ADL +T++ +  + +WN+T QWY G++ C+++ F +  +  SS ++   I +DR   ++    + D  K   I L   WSLS + +IPQ+ +   +       F QC  +   ++  +  +Y        FLLPL +++ CY  I++ I                      +H       +S++  L    N                    + RA+ ++L +S  I++T++   TPY++      LG++     + +   K+   LSH  F   +LN+  +PIIYG F 
Sbjct:   30 ITLLNDKAFVLPIFSTAAKIRVAITCILFVFSTCFNVAALWTITYKYRKKSH----IRILIINLVAADLFITLVVMPLDAVWNVTLQWYAGDLACRVLMFLKLAAMYSSAFVTVVISLDRQAAVLNPLGIRDAKKKNKIMLCVAWSLSYLLAIPQLFVFHTVSRSEPVHFVQCATVGSFQAHWQETIYNMFTFFCLFLLPLLIMVFCYARILMEI----------------------THKMKAACVSSKEIDLRRSSNN-------------------IPRARMRTLKMSLVIVLTFIVCWTPYYL------LGIWYWFSPEMLTKEKVPPSLSHILFLFGLLNTCLDPIIYGLFT 334          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: AVPR1A (arginine vasopressin receptor 1A [Source:NCBI gene;Acc:100488869])

HSP 1 Score: 86.6557 bits (213), Expect = 5.724e-18
Identity = 88/360 (24.44%), Postives = 158/360 (43.89%), Query Frame = 1
Query:    4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWK-KEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVN--SKLDELSHWFFWLSILNSAFNPIIYGYFNN 1056
            N   +  + + DP    +  +KI++ IL   F+ +V+GN   LI L K +++TS+     +  I HL +ADL+V    +L +  W +T ++ G ++LC+++K  +     +S Y++  +  DR   I   +++ +   K   + +I+ W +S + SIPQ  +      P    E Y C       F++    R Y        F++P+A++  CYGFI   I +  Q   K          ++    ++  LSTS  +  T                        +SRAK +++ ++  I+  Y+    P+++V   Q   V+D         D  +     L  LNS  NP IY +F+ 
Sbjct:   30 NSSSSQIDPTADPYVRNEALAKIEIAILAIIFVAAVLGNCSVLIGLYKSKKKTSR----MHLFIKHLSLADLAVAFFQVLPQLCWEVTYRFRGPDILCRIVKHLQVFGMFASAYMLVVMTADRYIAICHPLKTLQQPTKRSYVMIISAWIISFLLSIPQYFI--FSFSPVNGSEVYDC----WAHFIQPWGARAYITWMTASIFVVPVAILTTCYGFICYNIWRNIQCKTKRE--------ENEGRKSHGLLSTSVSSVKT------------------------ISRAKIRTVKMTLVIVTAYILCWAPFFIV---QMRSVWDKNFEWTDSEDIATTVTALLGSLNSCCNPWIYMFFSG 344          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: AVPR1B (arginine vasopressin receptor 1B [Source:NCBI gene;Acc:100487856])

HSP 1 Score: 84.3445 bits (207), Expect = 3.374e-17
Identity = 91/372 (24.46%), Postives = 180/372 (48.39%), Query Frame = 1
Query:   25 NYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVC-------IILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFF----WLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKP 1098
            NY TDP  N DL +K +V +L    +++   N++ L  + +RR++ ++     +  I+HL   DL+V +  +L + IW++T ++ G ++LC+ +K+ + +S  +STY++  + IDR   +   +++ +   K   + +   W LS I S+PQ+ +  +      KE  Q   + +  + + R YP+          +  F +P+ ++L CY  I   I K  +  GK+                       + +G+ ++E+     + P++     S R  +SRAK +++ ++  I+++Y+   TP++ V   Q   V+D   NS  ++ + + F     L+ L+S  NP IY  +N+    P   R   +P
Sbjct:   19 NY-TDPR-NEDL-AKAEVALLGAILVITTGSNLIVLFAIYQRRKKMTR----MHLFIVHLTFTDLAVALFQILPQMIWDITFRFIGSDILCRAVKYTQVMSMFASTYMLMMMTIDRYIAVCHPLKTLQQPSKQAYLMIGGTWILSCILSLPQIFIFSM------KEISQGAGV-IDCWADFR-YPWGAKAYITWITVSIFFVPVGILLLCYSLICCEICKNLK--GKM-----------------------QTSGVGQRESN--GQVVPSR---VSSIRT-ISRAKIRTVKMTFVIVLSYILCWTPFFSV---QMWSVWDE--NSPDEDSTDFAFTITMLLASLSSCSNPWIYMCYNS----PQLCRGTSRP 335          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Gnrhr (gonadotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:95790])

HSP 1 Score: 100.523 bits (249), Expect = 3.087e-23
Identity = 87/353 (24.65%), Postives = 161/353 (45.61%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK--RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL---GPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            +P   +  KI+VT+    F++S   N   L+ L K  ++R+  +       L+ HL +A+L  T++ +  + +WN+T QWY GE LCK++ + +  S  +  +++  I +DR   I +      + +L   M+ +     W LS +F+ PQ+ + +++    G     F QC  +     +     Y F      F++PL ++L C                K+ F L+ +L Q                             +P K  L QSK   + RA+ ++L ++ +   +++   TPY++      LG+   FD  ++N   + ++H+FF  + LN  F+P+IYGYF+
Sbjct:   28 LPTLTVSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITQPLAVQSNSKLEQSMISL----AWILSIVFAGPQLYIFRMIYLADGSGPTVFSQCVTHCSFPQWWHQAFYNFFTFGCLFIIPLLIMLICN--------------AKIIFALTRVLHQ-----------------------------DPRKLQLNQSKNN-IPRARLRTLKMTVAFATSFVVCWTPYYV------LGIWYWFDPEMLNRVSEPVNHFFFLFAFLNPCFDPLIYGYFS 326          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Npsr1 (neuropeptide S receptor 1 [Source:MGI Symbol;Acc:MGI:2441738])

HSP 1 Score: 84.3445 bits (207), Expect = 1.894e-17
Identity = 83/357 (23.25%), Postives = 162/357 (45.38%), Query Frame = 1
Query:   85 LLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV----ETRVYPFVCII--LAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFW------LSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQ 1113
            L   F+V++VGN V L    +R+R++  +F      +  L I D    ++ +LT+ IW  T  +   +++C+++++ + +   +STY++ ++ IDR   I+   +    +K   + +   WSLS +FSIP +    ++ G  K+      N E++ +     ++   P++ I+  L + +PLA+I   YG ++ TI                  M+  +H T   +S      L    N                 R  +S+AK K++  S  II+ ++   +PY++   L +  V        L +    F+       L  LNSA NP+IY  F++    P ++++ Q  ++ ++
Sbjct:   56 LWVLFVVTIVGNSVVLFSTCRRKRKSRMTF-----FVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTL----IIFG--KRTL---SNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTI-----------------WMKSKTHET--VISNCSDGKLCCSYN-----------------RGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNV--------LPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYR 354          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Avpr1a (arginine vasopressin receptor 1A [Source:MGI Symbol;Acc:MGI:1859216])

HSP 1 Score: 81.6481 bits (200), Expect = 2.268e-16
Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1
Query:   64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMK----SFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKA--GLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDT--IVNSKLDELSHWFFWLSILNSAFNPIIYGYFNN 1056
            +K++VT+L   F+V+V+GN   L+ L +  R+TS+     +  I HL +ADL+V    +L +  W++T ++ G + LC+++K  +  +  +S+Y++  +  DR   +   +++ +   +   + +   W LS + SIPQ  +  V+      EF      + +    +F+    TR Y        F++P+ ++  CYGFI   I +  +                      KT S   K   G  E    F++ L         S    +SRAK +++ ++  I+  Y+   TP+++V   Q   V+DT  +     +  +     L+ LNS  NP IY +F+ 
Sbjct:   51 AKLEVTVLAVIFVVAVLGNSSVLLALHRTPRKTSR----MHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGPDWLCRVVKHLQVFAMFASSYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAASWGLSFVLSIPQYFIFSVI------EFEVNNGTKAQDCWATFIPPWGTRAYVTWMTSGVFVVPVIILGTCYGFICYHIWRNVR---------------------GKTASRQSKGGKGSGEAAGPFHKGLLVTPCV---SSVKSISRAKIRTVKMTFVIVSAYILCWTPFFIV---QMWSVWDTNFVWTDSENPSTTITALLASLNSCCNPWIYMFFSG 358          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Gnrhr (gonadotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:95790])

HSP 1 Score: 77.7962 bits (190), Expect = 9.298e-16
Identity = 54/216 (25.00%), Postives = 104/216 (48.15%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK--RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL---GPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILK 654
            +P   +  KI+VT+    F++S   N   L+ L K  ++R+  +       L+ HL +A+L  T++ +  + +WN+T QWY GE LCK++ + +  S  +  +++  I +DR   I +      + +L   M+ +     W LS +F+ PQ+ + +++    G     F QC  +     +     Y F      F++PL ++L C   I+  + +
Sbjct:   28 LPTLTVSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITQPLAVQSNSKLEQSMISL----AWILSIVFAGPQLYIFRMIYLADGSGPTVFSQCVTHCSFPQWWHQAFYNFFTFGCLFIIPLLIMLICNAKIIFALTR 239          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Oxtr (oxytocin receptor [Source:MGI Symbol;Acc:MGI:109147])

HSP 1 Score: 77.7962 bits (190), Expect = 3.211e-15
Identity = 58/221 (26.24%), Postives = 114/221 (51.58%), Query Frame = 1
Query:   25 NYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRS-RRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQM 666
            N +  P    +  ++++V +L     +++ GN   L+ L   R + S+ F  F K   HL IADL V +  +L + +W++T ++YG ++LC+L+K+ + +   +STYL+  + +DR   I   +RS RR +D++ V   +  W    + S+PQ+    L +V  G      + C  + ++ +   + Y     +  +++P+ V+  CYG I   I +  ++
Sbjct:   26 NLTAGPPRRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFF-FMK---HLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAV---LATWLGCLVASVPQVHIFSLREVADG-----VFDCWAVFIQPW-GPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRL 233          
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|Q8CH60|GNRHR_CAVPO (Gonadotropin-releasing hormone receptor OS=Cavia porcellus OX=10141 GN=GNRHR PE=2 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 1.528e-26
Identity = 97/354 (27.40%), Postives = 164/354 (46.33%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG-----FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL---GPWKKE-FYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDE-LSHWFFWLSILNSAFNPIIYGYFN 1053
            +P   L  KI+VT+    F+VS   N     FLLK ++ T +  KG        L+ HL +A+L  T++ +  + +WN+T QWY GE+LCK++ + +  S  +  +++  I +DR   I R      +R+L   M  +     W LS++ + PQ+ + K++    GP + E F QC  +     +     Y F   I  F++PL ++L C                K+ F L+ +L Q                             + NK  L QSK   + RA+ ++L ++ +   +++   TPY   Y L     FD  +  ++ E ++H+FF  + LN  F+P+IYGYF+
Sbjct:   28 LPTLTLSGKIRVTVTFFLFLVSTTLNAS---FLLKLQKWTQKKEKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKILSYLKLFSMYAPAFMMVVISLDRSMAITRPLPVQSNRKLEQSMTGL----AWGLSSVLAGPQLYIFKMIHLENGPGQTEVFSQCVTHCSFPQWWHQAFYNFFTFICLFIIPLLIMLICN--------------AKIIFTLTQVLQQ-----------------------------DSNKLQLNQSKNN-IPRARLRTLKMTVAFAASFIVCWTPY---YVLGLWYWFDPGMLHRMSEPVNHFFFLFAFLNPCFDPLIYGYFS 327          
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|P49922|GNRHR_PIG (Gonadotropin-releasing hormone receptor OS=Sus scrofa OX=9823 GN=GNRHR PE=2 SV=2)

HSP 1 Score: 106.301 bits (264), Expect = 1.733e-24
Identity = 92/356 (25.84%), Postives = 162/356 (45.51%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK--RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVL----LGPWKKEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            +P   L  KI+VT+    F++S   N   L+ L K  +R++  +       L+ HL +A+L  T++ +  + +WN+T QWY GE LCK++ + +  S  +  +++  I +DR   I R      + RL   M+ +     W LS+IF+ PQ+ + +++         + F QC  +   SF +      Y F      F++PL ++L C   IM T+ +  Q                                            +P+   L QSK   + RA+ ++L ++ +   +++   TPY++      LG+   FD  +VN   D ++H+FF  + LN  F+P+IYGYF+
Sbjct:   28 LPTLTLSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQRKEKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLAVKSNSRLGRFMIGL----AWLLSSIFAGPQLYIFRMIHLADSSGQTEGFSQC--VTHGSFPQWWHQAFYNFFTFSCLFIIPLLIMLICNAKIMFTLTRVLQQ-------------------------------------------DPHNLQLNQSKNN-IPRARLRTLKMTVAFAASFIVCWTPYYV------LGIWYWFDPEMVNRVSDPVNHFFFLFAFLNPCFDPLIYGYFS 327          
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|P30968|GNRHR_HUMAN (Gonadotropin-releasing hormone receptor OS=Homo sapiens OX=9606 GN=GNRHR PE=1 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 1.504e-23
Identity = 94/353 (26.63%), Postives = 165/353 (46.74%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG-----FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL-SDKMVVICLITV-WSLSTIFSIPQMKLNKVL----LGPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            +P   L  KI+VT+    F++S   N     FLLK ++ T +  KG        L+ HL +A+L  T++ +  + +WN+T QWY GE+LCK++ + +  S  +  +++  I +DR   I R   L S+  V   ++ + W LS++F+ PQ+ + +++         K F QC  +     +     Y F      F++PL ++L C                K+ F L+ +L Q                             +P++  L QSK   + RA+ K+L ++ +   ++    TPY++      LG+   FD  ++N   D ++H+FF  + LN  F+P+IYGYF+
Sbjct:   28 LPTLTLSGKIRVTVTFFLFLLSATFNAS---FLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICN--------------AKIIFTLTRVLHQ-----------------------------DPHELQLNQSKNN-IPRARLKTLKMTVAFATSFTVCWTPYYV------LGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFS 327          
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|Q2V2K5|GNRHR_OCTVU (Gonadotropin-releasing hormone receptor OS=Octopus vulgaris OX=6645 GN=GNRHR PE=2 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 2.580e-23
Identity = 97/350 (27.71%), Postives = 166/350 (47.43%), Query Frame = 1
Query:   25 NYSTDPMPN---FDLHSKIKVTILLTFFIVSVVGN--IVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKE-FYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            N ++ P+P+   FD     K+ +L T F++S  GN  ++  IF ++  R T QS      LIL+L IADL V+   +L + IW+ T +W  G  +CK++K+        STY+  +I +DR   I+   SR  +   V I +   W LS IFSIPQ  + +     +++  F+QCR+    +  + ++Y    +IL F++PL +++  Y  I+ TI+K  +              Q H    +  +S +  +  +    Q   +L                RA+ +S  +S+ I+  ++   TPY++++       +D   NS+      +FF L   N   NP+IYG F
Sbjct:   15 NITSTPLPDAPRFDNVYVSKLCVLGTVFVISFFGNTLVIIQIFRIRGSRSTIQS------LILNLAIADLMVSFFNILMDIIWSATVEWLAGNTMCKIMKYLTVFGLHLSTYITVSIALDRCFAILSPMSRSKAPLRVRIMITMAWVLSAIFSIPQAVIFQEQRKMFRQGMFHQCRD-SYNALWQKQLYSASSLILLFVIPLIIMVTSYLLILKTIVKTSR--------------QFH----DTPISPTSMSCYSVNHGQIRTHL--------------FERARKRSSRMSAVIVAAFILCWTPYYIIFLGFAFFQWD---NSR---TVIYFFTLGTSNCMLNPLIYGAF 319          
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|Q19PY9|GNRHR_BOSMU (Gonadotropin-releasing hormone receptor OS=Bos mutus grunniens OX=30521 GN=GNRHR PE=3 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 2.851e-23
Identity = 90/353 (25.50%), Postives = 163/353 (46.18%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK-----RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL----GPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            +P   L  KI+VT+    F++S + N     FLLK     +R++  +       L+ HL +A+L  T++ +  + +WN+T QWY GE+LCK++ + +  S  +  +++  I +DR   I +  + + + K+    +   W LS+IF+ PQ+ +  ++         + F QC  +     +     Y F      F++PL +++ C                K+ F L+ +L Q                             +P+K  L QSK   + RA+ ++L ++ +   ++    TPY++      LG+   FD  +VN   D ++H+FF  + LN  FNP+IYGYF+
Sbjct:   28 LPTLTLSGKIRVTVTFFLFLLSTIFNTS---FLLKLQNWTQRKEKRKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITKPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGMIHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMVICN--------------AKIIFTLTRVLHQ-----------------------------DPHKLQLNQSKNN-IPRARLRTLKMTVAFATSFTVCWTPYYV------LGIWYWFDPDMVNRVSDPVNHFFFLFAFLNPCFNPLIYGYFS 327          
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A291FE86 (Gonadotropin-releasing hormone receptor 1 OS=Platynereis dumerilii OX=6359 PE=2 SV=1)

HSP 1 Score: 153.68 bits (387), Expect = 1.728e-38
Identity = 106/343 (30.90%), Postives = 169/343 (49.27%), Query Frame = 1
Query:   40 PMPNFDLHSKIKVTILLTFFIVSVVGNIVTLI--FLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEM-KSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            P P  +  S IK ++L T F++S+VGN  TL+  F ++RRR T       N LI+HL  ADL VT    L ++IW  T QW  G ++CKL+K+ +      STY++  I IDR   I+   SR  + + V + +IT W LS IFS PQ  +  V  GP+   +YQC       +  + ++Y  +  +L F++PL +++  Y  I  TI K+ + + K   + S   +     +    LS +                 P +  LFQ       +AK KSL +++ I++ ++   +PY++++    L    T +  +L   S W F     NS  NP+IY  F+
Sbjct:   72 PPPTANRMSTIKTSVLSTLFVISLVGNTATLVQMFRMRRRRST------INTLIMHLATADLIVTFFCFLADSIWVTTVQWLAGNIMCKLVKWLQVFGLYLSTYIVVIIAIDRAYAILDPMSRNKAPRRVRLMIITAWVLSAIFSAPQAYIFSVQRGPYSAPYYQCVTFGAYNARWQEQMYSIISALLMFIIPLIIMITAYMLIFTTIAKKSRDLKKGILIRSSCCISETEQAAADMLSQA-----------------PVRGELFQ-------KAKVKSLKMTTLIVLAFIICWSPYYVIF----LAYTFTDMTPQLKYASMWIFCFGTGNSLLNPLIYSAFH 380          
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A1C6ZYI2 (Corazonin receptor OS=Crassostrea gigas OX=29159 PE=2 SV=1)

HSP 1 Score: 149.443 bits (376), Expect = 4.296e-37
Identity = 107/343 (31.20%), Postives = 174/343 (50.73%), Query Frame = 1
Query:   31 STDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +  PMP     S +K  +L+  F +S +GN  TLI + + R++ S      N LI++L +ADL VT   +  E +W +T QW  G  +CK+++F +    L STY+   I +DR  VII   SR  + + V I +I  W LS +FSIPQ  L  V  GP+K++FYQC +I    S    ++Y   C+I+ F LPL +++  YG I  TI ++ +  G+          ++ S+S+++     E +G +                    +   L +AK K+L +S  I+I +     PY++V+     G + ++  S +  L+    ++ + NS  NPIIYG F
Sbjct:   51 TESPMPPTFQDSLVKTVVLILLFTISFIGNTATLIQMYRVRKRRST----INTLIVNLAVADLIVTFFCMAAEAVWALTVQWVAGVAMCKMLRFIQGTGLLVSTYITVVISLDRCCVIIDPISRNKAPQRVRIMIIMSWFLSALFSIPQALLFSVHRGPFKEDFYQCVDILGYPSPAYKKLYNIFCMIIQFFLPLTLMIIAYGLIFFTISRKSKEFGE---------PENVSNSSDQ----REHSGRS------------------HVRSGLLRKAKRKALRMSLFIVIAFFVCWLPYYVVFTGFAFGHWTSLDPSLMSGLT----FVGLTNSILNPIIYGAF 354          
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: V4BCY4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_103088 PE=4 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 5.995e-36
Identity = 108/362 (29.83%), Postives = 173/362 (47.79%), Query Frame = 1
Query:   46 PNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRS--RRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV---ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPR---IRKYQKPKII 1107
            P FD  +  K  +  T F+++ +GN+ TLI + + R + S      N LI++L I DL +       E IW  T QWYGG  +CK+IKF +  S   STY+   IG+DR   I+    R+ +   V   ++  W  S +FSIPQ  +  V  GP+K++FYQC  + M S+    +  VY     +L F++PL +I   YG I  TI ++ +   K              + T +T S ++      + N                    L +AK KSL +S  I++ ++   TPY++++       ++ I N ++  L  W F+L + N+  NP+IYG F       PR   +R ++  KI+
Sbjct:   29 PTFDDIAMTKCIVFGTMFVIAFIGNVATLIQMYRMRHRKST----INTLIVNLAIGDLFIVCFCFPVEGIWAATVQWYGGTAMCKIIKFIQVFSLYLSTYVTVAIGLDRCVAILDPMRRKSAPTRVRTMIMLAWFFSALFSIPQAIIFNVRRGPFKEDFYQC--VTMGSYPNAWQEEVYSIASFLLMFVIPLVIIGTAYGLIFSTIARKSKEFIK-------------KNPTVRTTSYNDIQRGPVRSN-------------------LLRKAKRKSLRMSIVIVVVFVMCWTPYYVIFICLTFLDWEEI-NPRIYRLVLWLFFLGMSNAVMNPLIYGAFQICKVHTPRSVHLRAFRSHKIL 351          
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A193KUK2 (GCR073 OS=Schmidtea mediterranea OX=79327 GN=gcr073 PE=2 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 1.288e-34
Identity = 113/366 (30.87%), Postives = 187/366 (51.09%), Query Frame = 1
Query:   22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI---LKQYQMIGKLSFMLSPLLMQHHSHSTNK-------TLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELS-HWFFWLSI-------LNSAFNPIIYG 1044
             N +   +P+F+ ++  K    L  F +S++GN  T+ F LK ++++  S++   ++I+ L  AD+ V + F+LT+ IWN+   W GG  LCKL+K G+  S   STY+++ + +DR   I      + S   + K+++ICL   W  S + +IPQ+ L     GPWK   FYQC   +  + ++  VYP V  +L  L+P+ +++ CY  I+ TI    K+Y+    ++ +          H TN+         S S     T   N+  +     ++ L   K+  +SRAK K+  +S+ II  +L    PYW+ Y      V  T+ N++L + +     W+S+       LNSAFNPIIYG
Sbjct:    6 NNLTLPKIPSFNGYNLFKSVFFLVVFFISILGNTHTIFFTLKLQKRSKLSYRSLYRMIMQLAFADILVCLFFVLTQAIWNIFVSWRGGSFLCKLMKMGQAFSIYLSTYIMSLVSLDRAIAICKPIHHLHSWNRNIKIIIICL---WIYSFLLAIPQVLLFDAYRGPWKTVTFYQCTTSDNLNILQMYVYPLVYCVLILLIPIGILVTCYTVIIHTINVRSKEYEEHNSVTILFHQPKSDDCEHLTNQFPFYDDAKHSGSNNDNETIVINRISENSNNFQKLLSHKKQQLMSRAKIKTYRMSAIIISCFLLCWLPYWVYY------VLITLKNARLIKFTLGKNIWISVFIQSLASLNSAFNPIIYG 362          
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A3G9D4B1 (Gonadotropin-releasing hormone receptor OS=Mizuhopecten yessoensis OX=6573 GN=gnrhr PE=2 SV=1)

HSP 1 Score: 140.198 bits (352), Expect = 1.502e-33
Identity = 112/399 (28.07%), Postives = 189/399 (47.37%), Query Frame = 1
Query:   31 STDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETR-VYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLV---LKHPLKVRRP 1209
            ST P P F+    ++  +L   F++S +GN  TLI + + R++ S      N LI++L IADL V    +  E  W +T Q+  G  +CK++++ +   FL STY+   I +DR  VI+   SR  + + V   +   W LS +FS+PQ+ +  VL GP+K++FYQC +I      + + +Y   C+ + F++PL +++  YG I  TI ++ +                     N T S     G  +  N                    L +AK K+L +S  I+I ++    PY++++     G ++ +  S +  LS     + + NS  NPIIYG F        ++ K  +P+++    W+T  +  K   N +I LLV    K   ++R P
Sbjct:   68 STSP-PVFNDAYMVETIVLSALFLISFIGNTATLIQMYRMRKRRST----INTLIVNLAIADLIVAFFCMAAEAFWTVTIQFLAGNAMCKILRYIQVFGFLLSTYITVVISLDRCCVILDPISRNKAPQRVRFMIGVSWLLSALFSVPQLLVFSVLRGPFKEDFYQCVDIASYPHPQYKWMYNIFCLFVQFMIPLGIMIAAYGLIFCTISRKSK-----------------EFRGNDTTSNKNDLGRGQVRNN------------------LLKKAKRKALRMSIFIVIAFVVCWFPYYVLFTGNAFGQWEELSPSLMAGLST----MGLSNSMLNPIIYGAF--------QLCKVHRPRLV----WRTVVS--KPSGNDSIYLLVKEGEKASFRIRTP 408          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: gnrhr4 (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:103034933])

HSP 1 Score: 100.138 bits (248), Expect = 1.107e-22
Identity = 86/346 (24.86%), Postives = 152/346 (43.93%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV----YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F   +K +V I  T   VS   N+  L       R+ S        LI++L +ADL VT + +  +  WN+T QW  G+  C+L+ F + ++  S  ++   I +DR   I+    +S+  K   I L   W++S + S+PQM +   +       F QC  R   +K + ET   ++ FVC+   FLLPL +++ CY  I++ I ++    G +S                                        +KE   +    ++ +A+ ++L +S  I+ +++   TPY+++    +FL      D +  +    L+H  F   + N+  +PI YG F
Sbjct:   40 LPTFSAAAKARVIITFTLCAVSAACNLAVLWAASTSTRRKSH----VRILIINLTVADLLVTFIVMPVDAAWNITVQWLAGDFACRLLMFLKLVAMYSCAFVTVVISLDRHSAILNPLAISEAKKKSKIMLSAAWAMSIVLSVPQMFIFHTVTITVPANFTQCTTRGSFVKHWQETLYNMFTFVCL---FLLPLVIMIFCYTRILLEISQRLSK-GNIS----------------------------------------SKEVHLRRSNNYIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLP-----DDLEETVSHSLTHMLFIFGLFNAILDPITYGLF 332          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: gnrhr4 (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:103034933])

HSP 1 Score: 100.138 bits (248), Expect = 1.132e-22
Identity = 86/346 (24.86%), Postives = 152/346 (43.93%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV----YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F   +K +V I  T   VS   N+  L       R+ S        LI++L +ADL VT + +  +  WN+T QW  G+  C+L+ F + ++  S  ++   I +DR   I+    +S+  K   I L   W++S + S+PQM +   +       F QC  R   +K + ET   ++ FVC+   FLLPL +++ CY  I++ I ++    G +S                                        +KE   +    ++ +A+ ++L +S  I+ +++   TPY+++    +FL      D +  +    L+H  F   + N+  +PI YG F
Sbjct:   47 LPTFSAAAKARVIITFTLCAVSAACNLAVLWAASTSTRRKSH----VRILIINLTVADLLVTFIVMPVDAAWNITVQWLAGDFACRLLMFLKLVAMYSCAFVTVVISLDRHSAILNPLAISEAKKKSKIMLSAAWAMSIVLSVPQMFIFHTVTITVPANFTQCTTRGSFVKHWQETLYNMFTFVCL---FLLPLVIMIFCYTRILLEISQRLSK-GNIS----------------------------------------SKEVHLRRSNNYIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLP-----DDLEETVSHSLTHMLFIFGLFNAILDPITYGLF 339          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: ENSAMXT00000039545.1 (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:103037789])

HSP 1 Score: 98.5969 bits (244), Expect = 2.180e-22
Identity = 86/348 (24.71%), Postives = 158/348 (45.40%), Query Frame = 1
Query:   46 PNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053
            P F   ++ +V   L  F+ + V N+  LI + + R +   S      LI+ L +ADL +T + +  + +WN+T QWYGG+ LCKL+ F +  +  +S +++  I +DR   I+       + R + +M    LI  WSLS +   PQ+ + + +    + +F QC  +   SF E     VY     +  +++PL V+  CY  I+I I +Q                +H             KAG               +  L +S+   + +A+ K+L ++  I+++++   TPY+++   Y+ Q       ++    + + H  F    LN+  +P+IYG + 
Sbjct:   36 PAFTRAAQFRVAATLVLFLFAAVSNLALLISVSRGRGRRLASH--LRPLIISLVVADLMMTFIVMPLDMVWNVTVQWYGGDGLCKLLSFLKLFAMQASAFILVVISLDRHHAILHPLDSLNAHRRNRRM----LILAWSLSLLLGSPQLFIFRTIKAE-RVDFTQC--VTHGSFRERWQETVYNMFHFVTLYVIPLLVMSCCYTHILIEINRQ----------------EH-----------KNKAG---------------ESCLRRSRTDMIPKARMKTLKMTIIIVMSFIVCWTPYYLLGIWYWFQ-----PEMLKVTPEYVHHLLFVFGNLNTCCDPVIYGLYT 327          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: gnrhr1 (gonadotropin releasing hormone receptor 1 [Source:ZFIN;Acc:ZDB-GENE-090128-2])

HSP 1 Score: 92.0485 bits (227), Expect = 3.924e-20
Identity = 81/346 (23.41%), Postives = 156/346 (45.09%), Query Frame = 1
Query:   46 PNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIE--MKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            P F   ++ +V   L  F+ + + N+  L+ + + R +   S      LI  L +ADL +T + +  + +WN+T QWY G+ +CKL+ F +  +  S+ +++  + +DR   I+       + R + KM    L+T W+LS + + PQ+ + + +      +F QC       K + ET  Y     +  ++ PL V+  CY  I++ I                          N+ ++ S+  G            EP    L +S    + +A+ K+L ++  I+ +++   TPY+++   Y+ Q       ++    + + H FF    LN+  +P+IYG+F
Sbjct:   31 PTFTTAARFRVVATLVLFVFAAISNLSVLLSVTRGRGRRLASH--LRPLIGSLALADLVMTFVVMPLDAVWNVTVQWYAGDAMCKLLCFLKLFAMHSAAFILVVVSLDRHHAILHPLDALDAGRRNRKM----LMTAWTLSVVLASPQLFIFRAIKAE-GVDFVQCATHGRFQKHWQET-AYNMFQFVTLYVFPLLVMSFCYTRILVEI--------------------------NRQMNRSKDKG------------EP---CLRRSGMDMIPKARMKTLKMTIIIVASFVICWTPYYLLGIWYWFQ-----PQMLQVIPEYVHHIFFVFGNLNTCCDPVIYGFF 322          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: oxtr (isotocin receptor [Source:NCBI gene;Acc:103033855])

HSP 1 Score: 87.0409 bits (214), Expect = 2.221e-18
Identity = 61/222 (27.48%), Postives = 114/222 (51.35%), Query Frame = 1
Query:   31 STDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRS-RRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQM 666
            + +P+   +  +K++V +L      ++ GN+  L+ L    R T          + HL IADL V +  +L + IW++T ++YG ++LC+L+K+ + +   +STY++  + +DR   +   +RS RR +D++ V+C    W LS IFS+PQ+    L +V  G      Y C       FV+    + Y     +  +++P+ ++  CYG I   I +  ++
Sbjct:   35 TVNPLKRNEEVAKVEVAVLALVLFFALAGNLCVLLAL----RTTKHGPSRMYYFMKHLSIADLVVAVFQVLPQLIWDITFRFYGPDLLCRLVKYLQIVGMFASTYMLVLMSVDRCLAVCQPLRSLRRRTDRLYVLC---SWLLSLIFSVPQVGIFSLREVGAG-----VYDCWG----DFVQPWGAKAYITWISLTVYVVPVGILSACYGLISFKIWQNVRL 240          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010165.1 (pep scaffold:Pmarinus_7.0:GL493405:1402:3508:1 gene:ENSPMAG00000009199.1 transcript:ENSPMAT00000010165.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.1965 bits (217), Expect = 2.682e-20
Identity = 60/208 (28.85%), Postives = 103/208 (49.52%), Query Frame = 1
Query:   64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI-----IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQ 663
            ++ +V      FI + + N+  L  +    R+T    +    LI++L  ADL +T + +  + +W++TTQWY GE  C+L+ F R L+  SS ++   I +DR   I     I   +  +K +   L   W LS + ++PQ+ L  V      K F QC  +   +FVE     +Y     +  F+LPL +++ CY  I++ I K+ +
Sbjct:   51 TQFRVISTFALFIFAAISNLTVLCTISHNHRKTKSHVR---ILIVNLTTADLLITFIVMPLDAVWHITTQWYAGEFACRLLMFLRLLAMYSSAFITVVISLDRHSAILNPLGIGKAKAKNKTM---LSVAWVLSVLLAVPQLFLFHVKSPKGNKNFVQC--VTHGNFVEQWHHNLYYMFTFVFLFILPLFIMIFCYCRILLEISKRMR 250          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001380.1 (pep scaffold:Pmarinus_7.0:GL477135:197258:202768:-1 gene:ENSPMAG00000001242.1 transcript:ENSPMAT00000001380.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.5817 bits (218), Expect = 1.778e-19
Identity = 63/228 (27.63%), Postives = 113/228 (49.56%), Query Frame = 1
Query:    4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKL-------NKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQ 657
            ++  T+   S   +   +  +K+++ +L     V++VGN+  L+ L+  R++TS+     +  I+HL IADL V    +L + IW +T ++ G + LC+ IK+ + L   +STY++  +G+DR   I   +R+ R S K     +   W LS +FS+PQ  +       N  ++  W  EF +           T+ Y        F++P+ +++ CYG I   I K 
Sbjct:   30 SINATLNGSSQHALDRNEEVAKVEIALLSIILFVAIVGNVCVLLALINTRKKTSR----MHLFIMHLSIADLVVAFFQVLPQLIWKITYRFNGSDFLCRAIKYLQILGMFASTYVLIMMGLDRYIAICHPLRTLRQSSKQSYQMIFVSWFLSMLFSLPQAFIFSMSEVENSGIIDCW-AEFIKPWG--------TKAYITWMTGSVFIIPVIILIWCYGMITFAIWKN 244          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010781.1 (pep scaffold:Pmarinus_7.0:GL479461:3925:14587:-1 gene:ENSPMAG00000009764.1 transcript:ENSPMAT00000010781.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.0182 bits (175), Expect = 3.037e-14
Identity = 90/353 (25.50%), Postives = 159/353 (45.04%), Query Frame = 1
Query:   22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHW--FFWLSILNSAFNPIIYGYFNN 1056
             N S   +   +  +K+++TIL      +VVGN   L+ LL  +++TS+     +  I+HL IADL V    +L + IW +T ++ G ++LC+ +K+ + L   +STY+           +IR+ + S     + ++  W +S +FS+PQ     L +V  G      Y C      +FVE    + Y     +  F+ P+AV+L CYG I   I +          M + +  +         ++T+  + ++   N                    +S+AK ++  ++  II+ Y+   TP+++V   Q   V+D    S   E S +     L+ LNS  NP IY +F+ 
Sbjct:   23 ANASESTLSRDEDLAKVEITILAIILCAAVVGNACVLLALLSTKKKTSR----MHLFIMHLSIADLVVAFFQVLPQLIWEVTFRFNGSDILCRTVKYLQILGMFASTYM-----------LIRTIQQSSTQSYMMILVSWLVSFLFSVPQAYIFSLREVQQG---TGVYDC----WAAFVEPWGLKAYVTWTAVAVFVAPVAVLLWCYGMITAEIWRN---------MRAKMERRGGRDGPVAPVATATASRVSSVRN--------------------ISKAKIRTTKMTFVIIVVYVFCWTPFFLV---QMWSVWD---GSAPFEGSAFTIVMLLASLNSCTNPWIYMFFSG 318          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: si:dkey-178o16.4 (si:dkey-178o16.4 [Source:ZFIN;Acc:ZDB-GENE-131127-163])

HSP 1 Score: 70.0922 bits (170), Expect = 1.161e-13
Identity = 39/141 (27.66%), Postives = 73/141 (51.77%), Query Frame = 1
Query:   64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVII-----RSRRLSDKMVVICLITVWSLSTIFSIPQ 471
            ++ +V +L   F  + +GN V L  L +RR+  S+     +  ++HLC+ADL V    +L +  W++T  +   +  C+ IK+ + +   +STY+I    +DR Q +        +R++     +C   VW +S + S+PQ
Sbjct:   23 ARAEVAVLFAMFACTTLGNSVLLTALYRRRKHASR----MHVFMVHLCLADLVVAFFQVLPQLAWDITDVFLASDFACRFIKYMQIVGMFASTYMIVGTTVDRYQAVCFPMVTFKKRMAYWNAPVC--AVWVVSLLLSVPQ 157          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008459.1 (pep scaffold:Pmarinus_7.0:GL478345:24256:33787:1 gene:ENSPMAG00000007650.1 transcript:ENSPMAT00000008459.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 1.432e-13
Identity = 72/319 (22.57%), Postives = 131/319 (41.07%), Query Frame = 1
Query:  115 GNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIV--NSKLDELSHWFFWLSILNSAFNPIIYGYFNN 1056
            GN   L+ L + RR+ S+     N  + HL +ADL+V    +L +  W++T ++ G + LC+L+K+ + +   +STY++           +R R    K     +   W+LS + S PQ+    L +V  G      + C   +       R Y     +  ++ P+ ++  CYG I++ I +  ++  +  +   P   Q  S   ++  S                                +SRAK +++ ++  II+ Y+   TP+   + +Q    +D     +   D        LS LNS  NP IY  F+ 
Sbjct:   62 GNGSVLLALSRTRRKASR----MNLFVKHLSVADLAVAAFQVLPQLSWDVTFRFRGPDALCRLVKYLQVVGMFASTYVL----------TLRRRGEPRKQAHAMVACAWALSALLSTPQVVIFSLREVEEG-----VFDCW-ADFGQPWGMRAYVTWITVSVYVAPVLILAACYGAILLEICRNLRLKTRGRYPKDPRGSQSQSPVCSRVSSVR-----------------------------CISRAKVRTIKMTLVIIVVYVVCWTPF---FVIQMWAAWDETAPDDDSSDPTYTIVMLLSSLNSCTNPWIYMSFSG 328          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO39861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8Q1])

HSP 1 Score: 66.6254 bits (161), Expect = 4.106e-12
Identity = 84/372 (22.58%), Postives = 158/372 (42.47%), Query Frame = 1
Query:    4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC----RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHST-------NKTLSTSEK----------AGLTEKENQFY-QYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSK---LDELSHWFFWLSILNSAFNPIIYG 1044
            NL  T    +T      D    ++ T+     + SVVGN + +  ++    +   ++     L  +L IA+L V+ +FLL   I+     W  G+ +C L    + LS L  T+ +A I I R  VI        K   + ++ +W  +T  + P    +K+++ P+  + Y C        + SF   R Y  V  +L ++LP+ +++  YG +   +      I  +   L+  +    +HST       N  +  SE           AG  +   QF+  + + + + ++++    L   +   L +  +II+ ++    PY + YFL++   FD +   K         + F ++ L SA +P+ YG
Sbjct:   14 NLTSTEPASATTEYEESDEMRYLRFTLFGVISLASVVGNAIIIKSVISIPYKKPLTYT----LTTNLAIAEL-VSTIFLLMLVIYEEIKTWPFGDFMCHLTSPIQILSGLVVTWSMALISIHRFVVITSPGSQYIKKQELLMVLLWLAATAITFPLFMYSKMVMSPFDPDTYWCFVLFPGDSLSSFPSYRTYHMVRFMLNYILPIVIMIAAYGALGFRLKYHIAFIRTVHSELT--VPNSGTHSTGAVTVNGNTDIEASEPNNDNNNDVILAGTKDPSRQFHASFSQTSSDVVYEN---LLIDLESDLLRMIYAIILIFVVCYIPYQVFYFLEY---FDVVSYQKWRYFTVCRRYIFLITCLPSALHPLCYG 372          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO36138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJL3])

HSP 1 Score: 63.929 bits (154), Expect = 3.046e-11
Identity = 82/353 (23.23%), Postives = 148/353 (41.93%), Query Frame = 1
Query:  100 IVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI----EMKSF--VETRVYPFVCIILAFLLPLAVILGCYGFIMITIL-------------------------KQYQMIGKLSFML-----SPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYG 1044
            I S++GN V +  + +   +   ++     L+ ++ +A+L  T+L   + + +     W  GE+LC +I   + LS L +T  +A I + R +V    RR+  S K +   +I++W+++   ++P    +  ++ P +K  Y C  +    ++K F   E R Y  +     F++P  V++  YG + + +                           Q Q  G +S  L     SP   Q   H  N + ST E+A    +E               Q KR  +S  +   L +   II+ +L    PY + + L++ GV +       D    + F L+   SA +PI YG
Sbjct:   48 IASLLGNSVVIKTVFENSLRKPMTYY----LVSNMAVAELIGTVLVPFSYS-YQEIFHWPFGELLCHIIAPLQVLSVLVTTTSLAAIALHRYKVFTSPRRVRVSGKTITCTIISLWAIAFFITLPSFLYHSHVISPTQKGKYWCLELVPGDQLKDFPSPELRKYYMIRFFCNFVIPACVMMFSYGVVSLQLRFHRNRAVRDVEMETGSDRTRETSASTQPQQQGTVSMELHEVVRSPPHAQQPQH--NASNSTREQA---TRERA-------------QRKRQAISGLETDLLKMIYLIILIFLVCYFPYQIFFLLEYFGVMNYKNWQYFDITRIYVFLLTCFPSAIHPICYG 377          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO36453 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIH9])

HSP 1 Score: 60.4622 bits (145), Expect = 3.138e-10
Identity = 46/161 (28.57%), Postives = 83/161 (51.55%), Query Frame = 1
Query:    4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTET-IWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRR--LSDKMVVICLITVWSLSTIFSIPQMK 477
            +L  T ++ +TDP+ +  L + IK+T+    F+VS  GN +  I +LKR++  + +    N  IL+L +ADL++T + +  +  +  M   W  G V+CK++   + L+  +S Y +  + + R   I+   R  LS       +I +W LS +   P M 
Sbjct:   16 SLDNTSESGTTDPVGSNHLRT-IKLTLYTLIFLVSAAGNTLVCIVILKRKKMKTVT----NYFILNLAVADLALTCICIPFDIPVQEMGYIWPYGAVMCKVLYPLQTLTLFASVYTLTAVSLTRYWAIVHPLRKQLSVSKAKTLVIAIWVLSLLPVAPYMN 171          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO36377 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIX0])

HSP 1 Score: 60.4622 bits (145), Expect = 4.242e-10
Identity = 57/202 (28.22%), Postives = 95/202 (47.03%), Query Frame = 1
Query:   52 FDLHSKIKVTILLTF-FIVSVVGN--IVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGG---EVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRR--LSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGF 633
            F    +I +TI  +  F+V++VGN  +V ++      R T+      N LI ++ +ADL +T         + +T  W+GG   + LCK     +  S   S + +  I +DR   II   +  L+ K+V   ++ +W+ +  F+ P   + KV L   K   Y C  +  +S    R Y  V  I  +++PLA+IL  Y F
Sbjct:   19 FPADIQIGLTIFASLIFVVALVGNSIVVYIVCSCNHMRNTT------NILIANMAVADLWITFDIPYVIKWFYITDTWFGGGFGDFLCKFCHSAQAGSVACSVFTLVCISLDRSFAIIFPMKVILTRKIVKFMILGIWAATIAFTTPIFLITKVHL---KNGVYVCNELWEESGQSERHYIAVYTITTYIIPLALILIMYIF 211          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO41654 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3S0])

HSP 1 Score: 56.6102 bits (135), Expect = 4.520e-9
Identity = 54/219 (24.66%), Postives = 99/219 (45.21%), Query Frame = 1
Query:  103 VSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFL-LTETIWNMTTQWYGG---EVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRS--RRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLS 741
            VS +GN + +   + RR+      + F++LI+++ +ADL  TI  +    + + +  +W+ G   E  CK + FG N+S  +S + +A I +DR   I     R LS + V   + T+W ++ +         +V+ GP   + Y  ++         ++   V  +L +  PL   +G    IMI  L Q +  G  S  +   + +    S  K L+
Sbjct:    1 VSAIGNAMVIRHAVARRKLR----RSFDRLIINMAVADLLDTIFGVPYNISYFYIGLRWFPGTLGEFTCKFLNFGTNISITASVFTLAAIAVDRYFAIAHCAKRPLSLRSVRYIIATIWVIACMVFSSDYYRFRVIDGP-NGDVYCLQDANAWGKKAVQIDYIVKFVLNYAFPL-FAMGILYSIMIRYLWQTRGPGYASDSIERRVHEQRKRSVKKLLA 213          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: GNRHR (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:101167607])

HSP 1 Score: 96.2857 bits (238), Expect = 2.488e-21
Identity = 85/352 (24.15%), Postives = 154/352 (43.75%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI-----IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETR------VYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F   +K++V I       S   N+  L       ++ S        LI++L +ADL VT + +  + +WN+T QW  G+  C+L+ F +  +  S  ++   I +DR   I     I   R+ ++++   LI  W++S I S+PQ+ L   +   + +EF QC      SFV  R      ++ F C+   FLLPL +++ CY  I   I K+ +                                   ++N       P+ E   +  +  + +A+ ++L +S  I+++++   TPY++      LG++     D +       L+H  F   +LN+  +P+IYG F
Sbjct:   52 LPTFSTAAKVRVIITFILCGFSAFFNLAVLWAAQSDGKRKSH----VKVLIINLTVADLLVTFIVMPLDAVWNITVQWLAGDFACRLLMFLKLQAMYSCAFVTVVISLDRQSAILNPLAINKARMRNRVM---LIAAWAMSVILSVPQIFLFHNVTIIYPEEFTQCAT--RGSFVSHRHETAYNLFTFACL---FLLPLVIMITCYTRIFCEISKRLK-----------------------------------RDNL------PSSELHLRCSKNNIPKARMRTLKMSIVIVLSFIICWTPYYL------LGLWYWFSPDDLEGKVSHSLTHILFIFGLLNACLDPVIYGLF 344          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: gnrh-r3 (gonadotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100125529])

HSP 1 Score: 95.5153 bits (236), Expect = 2.587e-21
Identity = 87/349 (24.93%), Postives = 156/349 (44.70%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVET------RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDE-----LSHWFFWLSILNSAFNPIIYGYF 1050
            +P F   +K++V I  T   VS V N++ L    K  ++ S        LI++L +ADL VT + +  +  WN+T QW  G++ C+L+ F + ++  S  ++   I +DR   I+    +S+  +   I L   W+ S I S+PQM +   +     + F QC      SFV+        ++ FVC+   FLLPL +++ CY  I++ I  +       + M+S  +    SH+                                      + +A+ ++L +S  I+ +++   TPY++      LG++  +   K++E     L+H  F   + N+  +PI YG F
Sbjct:   32 LPTFSTAAKVRVIITFTLCAVSAVCNLLVLWAAGKGGKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWQAGDLACRLLMFMKLVAMYSCAFVTVVISLDRQSAILNPLGISEAKRKSKIMLTVAWTTSVILSLPQMFIFHNVTITVPENFTQC--TTHGSFVQRWQETLYNMFTFVCL---FLLPLVIMIFCYTRILVEISSRIAR----NNMVSRDIHLRRSHNN-------------------------------------IPKARMRTLKMSIVIVTSFIICWTPYYL------LGLWYWLFPEKMEETVSHSLTHMLFIFGLFNACLDPITYGLF 324          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: gnrh-r1 (gonadotropin-releasing hormone receptor 1 [Source:NCBI gene;Acc:100125422])

HSP 1 Score: 93.2041 bits (230), Expect = 1.639e-20
Identity = 88/349 (25.21%), Postives = 150/349 (42.98%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKL--NKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F   +K++V I      VS + N   L   +  +R++         LI++L  ADL VT + +  +  WN+T QW  G+  C+ + F +  +  S  ++   I +DR   I+R   +S   +     L   W++S + S+PQM +  N  +  P    F QC  R   +  + ET   ++ F C+   FLLPL++++ CY  I I I KQ                      T K +S+ E      K N                    + +A+ ++L +S  I++ ++   TPY++      LG++     D +       L+H  F   + N+  +PIIYG F
Sbjct:   44 LPTFSTAAKVRVIITFILCGVSTLCNSAVLWAAIGHKRKSH-----VRVLIINLTAADLLVTFIVMPVDAAWNITVQWLAGDAACRFLMFLKLQAMYSCAFVTVVISLDRQSAILRPLSISAAPRRNRSMLTVAWTMSAVLSVPQMFIFHNVTITHP--ANFTQCTTRGSFVTHWQETAYNMFTFTCL---FLLPLSIMIICYTRIFIQISKQM---------------------TKKNVSSDEPHLRCSKNN--------------------IPKARMRTLKMSVVIVVGFIVCWTPYYL------LGLWYWFFPDDLEGKVSHSLTHILFIFGLFNTCLDPIIYGLF 335          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: gnrh-r1 (gonadotropin-releasing hormone receptor 1 [Source:NCBI gene;Acc:100125422])

HSP 1 Score: 93.2041 bits (230), Expect = 1.639e-20
Identity = 88/349 (25.21%), Postives = 150/349 (42.98%), Query Frame = 1
Query:   43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKL--NKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            +P F   +K++V I      VS + N   L   +  +R++         LI++L  ADL VT + +  +  WN+T QW  G+  C+ + F +  +  S  ++   I +DR   I+R   +S   +     L   W++S + S+PQM +  N  +  P    F QC  R   +  + ET   ++ F C+   FLLPL++++ CY  I I I KQ                      T K +S+ E      K N                    + +A+ ++L +S  I++ ++   TPY++      LG++     D +       L+H  F   + N+  +PIIYG F
Sbjct:   44 LPTFSTAAKVRVIITFILCGVSTLCNSAVLWAAIGHKRKSH-----VRVLIINLTAADLLVTFIVMPVDAAWNITVQWLAGDAACRFLMFLKLQAMYSCAFVTVVISLDRQSAILRPLSISAAPRRNRSMLTVAWTMSAVLSVPQMFIFHNVTITHP--ANFTQCTTRGSFVTHWQETAYNMFTFTCL---FLLPLSIMIICYTRIFIQISKQM---------------------TKKNVSSDEPHLRCSKNN--------------------IPKARMRTLKMSVVIVVGFIVCWTPYYL------LGLWYWFFPDDLEGKVSHSLTHILFIFGLFNTCLDPIIYGLF 335          
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: v1ar1 (arg8-vasotocin receptor-like [Source:NCBI gene;Acc:101155395])

HSP 1 Score: 91.6633 bits (226), Expect = 7.983e-20
Identity = 66/222 (29.73%), Postives = 116/222 (52.25%), Query Frame = 1
Query:    1 ENLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQ---MKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI 648
            + L    KN+S DP    +  +KI++T+L   F+ +VVGN+  L+ + + RR+ S+     +  + HL +ADL V    +L +  W +T ++YG + LC+++K  + L   +STY++  + +DR   I   +++ +   +   I + + W+ S + S PQ     L++V  G      Y C    M+ +   R Y        FLLP+A+++ CYGFI  TI
Sbjct:   22 QQLGGVKKNHS-DPFGRNEEVAKIEITVLSLAFVAAVVGNVSVLLAMHRTRRKLSR----MHLFMKHLSLADLVVAFFQVLPQLCWEITFRFYGPDFLCRIVKHLQVLGMFASTYMMVMMTLDRYIAICHPLKTLQQPTQRAYIMIGSTWACSLVLSTPQYFIFSLSEVRPG---SAVYDCWGHFMEPW-GLRAYITWITAGIFLLPVAILVFCYGFICRTI 234          
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000002693.1 (SMESG000002693.1)

HSP 1 Score: 805.053 bits (2078), Expect = 0.000e+0
Identity = 403/403 (100.00%), Postives = 403/403 (100.00%), Query Frame = 1
Query:   19 MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLVLKHPLKVRRPTQRVSL 1227
            MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMISSSIIITYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLVLKHPLKVRRPTQRVSL
Sbjct:    1 MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMISSSIIITYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLVLKHPLKVRRPTQRVSL 403          
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000074847.1 (SMESG000074847.1)

HSP 1 Score: 129.413 bits (324), Expect = 1.484e-33
Identity = 97/321 (30.22%), Postives = 164/321 (51.09%), Query Frame = 1
Query:   22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI---LKQYQMIGKLSFMLSPLLMQHHSHSTNK-------TLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFL 933
             N +   +P+F+ ++  K    L  F +S++GN  T+ F LK ++++  S++   ++I+ L  AD+ V + F+LT+ IWN+   W GG  LCKL+K G+  S   STY+++ + +DR   I      + S   + K+++ICL   W  S + +IPQ+ L     GPWK   FYQC   +  + ++  VYP V  +L  L+P+ +++ CY  I+ TI    K+Y+    ++ +          H TN+         S S     T   N+  +     ++ L   K+  +SRAK K+  +S+ II  +L    PYW+ Y L
Sbjct:    6 NNLTLPKIPSFNGYNLFKSVFFLVVFFISILGNTHTIFFTLKLQKRSKLSYRSLYRMIMQLAFADILVCLFFVLTQAIWNIFVSWRGGSFLCKLMKMGQAFSIYLSTYIMSLVSLDRAIAICKPIHHLHSWNRNIKIIIICL---WIYSFLLAIPQVLLFDAYRGPWKTVTFYQCTTSDNLNILQMYVYPLVYCVLILLIPIGILVTCYTVIIHTINVRSKEYEEHNSVTILFHHPKSDDCEHLTNQFPFYDDAKHSGSNNDNETIVINRISENSNNFQKLLSHKKQQLMSRAKIKTYRMSAIIISCFLLCWLPYWVYYVL 323          
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000074847.1 (SMESG000074847.1)

HSP 1 Score: 116.701 bits (291), Expect = 1.490e-29
Identity = 75/244 (30.74%), Postives = 131/244 (53.69%), Query Frame = 1
Query:   22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI---LKQYQMIGKLSFMLSPLLMQHHSHSTNK 732
             N +   +P+F+ ++  K    L  F +S++GN  T+ F LK ++++  S++   ++I+ L  AD+ V + F+LT+ IWN+   W GG  LCKL+K G+  S   STY+++ + +DR   I   I      ++ + I +I +W  S + +IPQ+ L     GPWK   FYQC   +  + ++  VYP V  +L  L+P+ +++ CY  I+ TI    K+Y+    ++ +          H TN+
Sbjct:    6 NNLTLPKIPSFNGYNLFKSVFFLVVFFISILGNTHTIFFTLKLQKRSKLSYRSLYRMIMQLAFADILVCLFFVLTQAIWNIFVSWRGGSFLCKLMKMGQAFSIYLSTYIMSLVSLDRAIAICKPIHHLHSWNRNIKIIIICLWIYSFLLAIPQVLLFDAYRGPWKTVTFYQCTTSDNLNILQMYVYPLVYCVLILLIPIGILVTCYTVIIHTINVRSKEYEEHNSVTILFHHPKSDDCEHLTNQ 249          
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000049782.1 (SMESG000049782.1)

HSP 1 Score: 100.138 bits (248), Expect = 3.591e-23
Identity = 105/366 (28.69%), Postives = 170/366 (46.45%), Query Frame = 1
Query:   19 MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKL--NKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLS-------FMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQ----FYQYLEPNKEFLF----QSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050
            ++NY+ +       + K+K  +LLT F++S+  N+  L F  + RR  S      N LI+HLC AD+   IL +  E +W +T QW     LCK  KF  + S   ST +I  + IDR  VI+   +R    K + I +  ++  S + +I Q+ +        P+   F QC +I +   V+    +V  ++  +  + LPL +I+ CY  I+ T LK      KL+       F   P ++      ++  LS  +      KEN     F +   P     F    +SK     RAK KS+ ++ SI++T++   TPY++VYF++       I      +   + F+   LN+  NPII G F
Sbjct:    9 LRNYTIE----LGWYHKMKFCVLLTMFVMSLGTNVFVLAFAYRIRRIKST----LNILIIHLCYADILAGILCMFGECLWILTIQWNASSWLCKFYKFSISFSISLSTGIICVMSIDRTLVIMYPLNRLKMAKRIKILIGIMYMGSCLINISQVTMFDTAQAPAPYPLPFIQCVHISLFMKVQQWRLKVVFWMHYVFNYALPLIIIIVCYSLIL-TRLKDASRWNKLNNFHQRYCFSKPPSVISMSQECSSSILSCKQ-----SKENNSIILFSKIHSPTSNHSFSHNLKSKNTLFRRAKKKSIKLTFSIVLTFVVCWTPYYIVYFIRSYS--GPIHRFDPRDPGIYSFFFGHLNAIINPIICGVF 358          
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000046683.1 (SMESG000046683.1)

HSP 1 Score: 83.9593 bits (206), Expect = 7.482e-18
Identity = 58/164 (35.37%), Postives = 86/164 (52.44%), Query Frame = 1
Query:   19 MKNYS-----TDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKM------VVICLITVWSLSTIFSIPQMK 477
            MKN +     T PMP  + ++  K     T F +SVVGN  T+ F+LK  R +  S    +K +L L +AD+SV I F+L   I N    W  G  +CK +K  +  S   STY++  I IDRV V IR   L  +       V+IC  ++W ++ + S+PQ++
Sbjct:    1 MKNVTSVQNVTIPMPQLNGYNLFKAIFFYTSFSISVVGNFNTIFFILKIYRHSKVSCIHLHKTLLQLALADISVAIFFILNLAILNTLGSWQAGRWVCKFVKVWQAFSIYLSTYVVVFISIDRV-VAIRFPLLHSRCWKRYFNVIIC--SIWLITFVLSLPQIQ 161          
The following BLAST results are available for this feature:
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GNRHR3.132e-2426.63gonadotropin releasing hormone receptor [Source:HG... [more]
AVPR1B1.748e-1622.58arginine vasopressin receptor 1B [Source:HGNC Symb... [more]
GNRHR4.138e-1631.76gonadotropin releasing hormone receptor [Source:HG... [more]
NPSR17.093e-1522.35neuropeptide S receptor 1 [Source:HGNC Symbol;Acc:... [more]
NPSR11.510e-1322.16neuropeptide S receptor 1 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gnrr-14.728e-1925.08GoNadotropin-Releasing hormone Receptor (GnRHR) re... [more]
gnrr-15.064e-1925.08GoNadotropin-Releasing hormone Receptor (GnRHR) re... [more]
gnrr-51.051e-1231.43GoNadotropin-Releasing hormone Receptor (GnRHR) re... [more]
npr-21.209e-1225.96NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
npr-21.503e-1225.96NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CrzR6.433e-2628.33gene:FBgn0036278 transcript:FBtr0075989[more]
CrzR9.039e-2628.33gene:FBgn0036278 transcript:FBtr0330069[more]
AkhR2.488e-2126.97gene:FBgn0025595 transcript:FBtr0332331[more]
AkhR2.488e-2126.97gene:FBgn0025595 transcript:FBtr0079309[more]
AkhR2.488e-2126.97gene:FBgn0025595 transcript:FBtr0079308[more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gnrhr48.902e-2224.64gonadotropin releasing hormone receptor 4 [Source:... [more]
gnrhr48.902e-2224.64gonadotropin releasing hormone receptor 4 [Source:... [more]
gnrhr48.902e-2224.64gonadotropin releasing hormone receptor 4 [Source:... [more]
avpr1ab6.552e-2124.93arginine vasopressin receptor 1Ab [Source:ZFIN;Acc... [more]
gnrhr22.445e-2025.00gonadotropin releasing hormone receptor 2 [Source:... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nrg31.460e-2225.29neuregulin 3 [Source:Xenbase;Acc:XB-GENE-984146][more]
ccbe11.620e-2126.09collagen and calcium binding EGF domains 1 [Source... [more]
gnrhr1.076e-2024.44gonadotropin releasing hormone receptor [Source:NC... [more]
AVPR1A5.724e-1824.44arginine vasopressin receptor 1A [Source:NCBI gene... [more]
AVPR1B3.374e-1724.46arginine vasopressin receptor 1B [Source:NCBI gene... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gnrhr3.087e-2324.65gonadotropin releasing hormone receptor [Source:MG... [more]
Npsr11.894e-1723.25neuropeptide S receptor 1 [Source:MGI Symbol;Acc:M... [more]
Avpr1a2.268e-1624.64arginine vasopressin receptor 1A [Source:MGI Symbo... [more]
Gnrhr9.298e-1625.00gonadotropin releasing hormone receptor [Source:MG... [more]
Oxtr3.211e-1526.24oxytocin receptor [Source:MGI Symbol;Acc:MGI:10914... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8CH60|GNRHR_CAVPO1.528e-2627.40Gonadotropin-releasing hormone receptor OS=Cavia p... [more]
sp|P49922|GNRHR_PIG1.733e-2425.84Gonadotropin-releasing hormone receptor OS=Sus scr... [more]
sp|P30968|GNRHR_HUMAN1.504e-2326.63Gonadotropin-releasing hormone receptor OS=Homo sa... [more]
sp|Q2V2K5|GNRHR_OCTVU2.580e-2327.71Gonadotropin-releasing hormone receptor OS=Octopus... [more]
sp|Q19PY9|GNRHR_BOSMU2.851e-2325.50Gonadotropin-releasing hormone receptor OS=Bos mut... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A291FE861.728e-3830.90Gonadotropin-releasing hormone receptor 1 OS=Platy... [more]
A0A1C6ZYI24.296e-3731.20Corazonin receptor OS=Crassostrea gigas OX=29159 P... [more]
V4BCY45.995e-3629.83G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A193KUK21.288e-3430.87GCR073 OS=Schmidtea mediterranea OX=79327 GN=gcr07... [more]
A0A3G9D4B11.502e-3328.07Gonadotropin-releasing hormone receptor OS=Mizuhop... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gnrhr41.107e-2224.86gonadotropin-releasing hormone II receptor-like [S... [more]
gnrhr41.132e-2224.86gonadotropin-releasing hormone II receptor-like [S... [more]
ENSAMXT00000039545.12.180e-2224.71gonadotropin-releasing hormone II receptor-like [S... [more]
gnrhr13.924e-2023.41gonadotropin releasing hormone receptor 1 [Source:... [more]
oxtr2.221e-1827.48isotocin receptor [Source:NCBI gene;Acc:103033855][more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000010165.12.682e-2028.85pep scaffold:Pmarinus_7.0:GL493405:1402:3508:1 gen... [more]
ENSPMAT00000001380.11.778e-1927.63pep scaffold:Pmarinus_7.0:GL477135:197258:202768:-... [more]
ENSPMAT00000010781.13.037e-1425.50pep scaffold:Pmarinus_7.0:GL479461:3925:14587:-1 g... [more]
si:dkey-178o16.41.161e-1327.66si:dkey-178o16.4 [Source:ZFIN;Acc:ZDB-GENE-131127-... [more]
ENSPMAT00000008459.11.432e-1322.57pep scaffold:Pmarinus_7.0:GL478345:24256:33787:1 g... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO398614.106e-1222.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361383.046e-1123.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO364533.138e-1028.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO363774.242e-1028.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO416544.520e-924.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GNRHR2.488e-2124.15gonadotropin-releasing hormone II receptor-like [S... [more]
gnrh-r32.587e-2124.93gonadotropin-releasing hormone receptor 3 [Source:... [more]
gnrh-r11.639e-2025.21gonadotropin-releasing hormone receptor 1 [Source:... [more]
gnrh-r11.639e-2025.21gonadotropin-releasing hormone receptor 1 [Source:... [more]
v1ar17.983e-2029.73arg8-vasotocin receptor-like [Source:NCBI gene;Acc... [more]
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BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000002693.10.000e+0100.00SMESG000002693.1[more]
SMESG000074847.11.484e-3330.22SMESG000074847.1[more]
SMESG000074847.11.490e-2930.74SMESG000074847.1[more]
SMESG000049782.13.591e-2328.69SMESG000049782.1[more]
SMESG000046683.17.482e-1835.37SMESG000046683.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030787 ID=SMED30030787|Name=Gonadotropin-releasing hormone receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1242bp
GAAAATTTAAAAGTTACCATGAAGAATTATTCAACTGATCCGATGCCGAA
TTTTGATTTACACAGCAAAATCAAGGTGACAATTTTGTTAACATTTTTCA
TCGTTTCGGTTGTGGGAAATATTGTCACTTTGATTTTTCTATTGAAAAGA
CGTCGACAAACAAGTCAATCTTTCAAAGGTTTTAATAAATTGATTCTCCA
TCTTTGCATTGCCGATTTGTCAGTTACGATTCTTTTCCTCCTAACCGAGA
CTATTTGGAATATGACGACCCAATGGTATGGAGGAGAGGTTCTGTGTAAG
TTGATAAAGTTTGGCCGGAATCTCAGCTTTCTGTCTAGCACTTATTTGAT
TGCCACAATTGGCATAGACCGAGTACAAGTTATAATACGGTCACGTCGGT
TGAGTGATAAAATGGTGGTTATTTGTTTGATAACAGTCTGGAGTCTAAGT
ACAATATTTTCAATTCCCCAGATGAAACTAAACAAAGTACTTCTTGGTCC
ATGGAAAAAAGAATTTTATCAATGCCGCAATATTGAAATGAAATCCTTTG
TCGAAACTCGGGTTTATCCATTTGTTTGTATAATTTTGGCTTTTCTTTTG
CCTTTAGCTGTGATTCTGGGATGTTACGGATTCATAATGATAACAATTTT
AAAGCAATATCAAATGATTGGTAAACTATCGTTCATGCTGAGCCCTCTAT
TGATGCAGCATCACAGTCATTCTACGAACAAAACGTTATCAACATCTGAA
AAGGCAGGTTTAACGGAGAAAGAAAATCAGTTTTACCAATATTTGGAACC
AAATAAAGAATTCCTTTTCCAAAGTAAAAGAGCCTTTCTATCAAGAGCAA
AATTTAAATCTTTAATGATCTCTTCGTCGATTATCATTACATATTTGACA
TCGAGAACCCCTTACTGGATGGTGTATTTTCTTCAGCATCTTGGAGTATT
TGACACGATAGTCAATTCGAAATTGGACGAATTGAGCCATTGGTTCTTTT
GGCTAAGTATTTTGAATTCGGCGTTCAATCCAATTATTTACGGATATTTC
AATAATCTCTGGTTTCTGCCGCCCAGAATTAGAAAATATCAAAAACCGAA
AATTATATTCCAAATCACCTGGAAAACCAAATGTAACAAGTTCAAAAAAC
AGTACAACCCAAATATCAGCTTGCTTGTTCTAAAACATCCTCTAAAGGTT
CGTCGTCCGACTCAAAGAGTTTCTTTATAATATCATTTACTT
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protein sequence of SMED30030787-orf-1

>SMED30030787-orf-1 ID=SMED30030787-orf-1|Name=SMED30030787-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=410bp
ENLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKR
RRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCK
LIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLS
TIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLL
PLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSE
KAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMISSSIIITYLT
SRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF
NNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLVLKHPLKV
RRPTQRVSL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0016500protein-hormone receptor activity
GO:0004930G-protein coupled receptor activity
GO:0004871signal transducer activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000419prepharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007165signal transduction
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 24..48
score: 20.18
coord: 138..159
score: 19.51
coord: 329..355
score: 27.66
coord: 106..128
score: 24.44
coord: 61..82
score: 27.71
coord: 190..213
score: 28.88
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 40..347
e-value: 2.5E-33
score: 115.5
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 18..353
e-value: 1.0E-45
score: 158.2
NoneNo IPR availablePANTHERPTHR24241NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTORcoord: 17..351
NoneNo IPR availablePANTHERPTHR24241:SF163ADIPOKINETIC HORMONE RECEPTOR, ISOFORM Ccoord: 17..351
NoneNo IPR availableCDDcd153847tmA_GnRHR_invertebratecoord: 24..350
e-value: 2.98179E-39
score: 140.265
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 9..352
NoneNo IPR availableTMHMMTMhelixcoord: 190..212
NoneNo IPR availableTMHMMTMhelixcoord: 287..309
NoneNo IPR availableTMHMMTMhelixcoord: 64..86
NoneNo IPR availableTMHMMTMhelixcoord: 139..158
NoneNo IPR availableTMHMMTMhelixcoord: 333..355
NoneNo IPR availableTMHMMTMhelixcoord: 26..48
NoneNo IPR availableTMHMMTMhelixcoord: 108..127
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 39..347
score: 28.536