Gonadotropin-releasing hormone receptor
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030787 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: GNRHR (gonadotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4421]) HSP 1 Score: 103.605 bits (257), Expect = 3.132e-24 Identity = 94/353 (26.63%), Postives = 165/353 (46.74%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG-----FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL-SDKMVVICLITV-WSLSTIFSIPQMKLNKVL----LGPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 +P L KI+VT+ F++S N FLLK ++ T + KG L+ HL +A+L T++ + + +WN+T QWY GE+LCK++ + + S + +++ I +DR I R L S+ V ++ + W LS++F+ PQ+ + +++ K F QC + + Y F F++PL ++L C K+ F L+ +L Q +P++ L QSK + RA+ K+L ++ + ++ TPY++ LG+ FD ++N D ++H+FF + LN F+P+IYGYF+ Sbjct: 28 LPTLTLSGKIRVTVTFFLFLLSATFNAS---FLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICN--------------AKIIFTLTRVLHQ-----------------------------DPHELQLNQSKNN-IPRARLKTLKMTVAFATSFTVCWTPYYV------LGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFS 327
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: AVPR1B (arginine vasopressin receptor 1B [Source:HGNC Symbol;Acc:HGNC:896]) HSP 1 Score: 82.4185 bits (202), Expect = 1.748e-16 Identity = 77/341 (22.58%), Postives = 165/341 (48.39%), Query Frame = 1 Query: 64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI----LNSAFNPIIYGYFNN 1056 +K+++ +L T +++ GN+ L+ L + R+ S+ + +LHL + DL+V + +L + +W++T ++ G ++LC+ +K+ + LS +STY++ + +DR + +RS + + + + W L+ IFS+PQ+ L +V+ G + + + R Y + F+LP+ ++ CY I I K + + ++ + + + TL+ + + GL + + +SRAK +++ ++ I++ Y+ P+ + +Q V+D N+ ++ ++ F +S+ LNS NP IY FN+ Sbjct: 34 AKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSR----MHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWA----DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLK-VKTQAWRVGGGGWRTWDRPSPSTLAATTR-GLPSRVSSINT----------------ISRAKIRTVKMTFVIVLAYIACWAPF---FSVQMWSVWDK--NAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNS 343
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: GNRHR (gonadotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4421]) HSP 1 Score: 78.9518 bits (193), Expect = 4.138e-16 Identity = 54/170 (31.76%), Postives = 91/170 (53.53%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFN----KLIL-HLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL-SDKMVVICLIT-VWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRN 531 +P L KI+VT+ F++S N FLLK ++ T + KG KL+L HL +A+L T++ + + +WN+T QWY GE+LCK++ + + S + +++ I +DR I R L S+ V ++ W LS++F+ PQ+ L+ + QC+N Sbjct: 28 LPTLTLSGKIRVTVTFFLFLLSATFNAS---FLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHH---PSFHHADLQCKN 191
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: NPSR1 (neuropeptide S receptor 1 [Source:HGNC Symbol;Acc:HGNC:23631]) HSP 1 Score: 77.0258 bits (188), Expect = 7.093e-15 Identity = 80/358 (22.35%), Postives = 159/358 (44.41%), Query Frame = 1 Query: 85 LLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV----ETRVYPFVCII--LAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI-------LNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQ 1113 L F+ ++VGN V L +R++++ +F + L I D ++ +LT+ W T + +++C+++++ + + +STY++ ++ IDR I+ + +K + ++ WSLS +FSIP + ++ G K+ N E++ + ++ P++ I+ L + +PL +I YG ++ TI + S + +S L N R +S+AK K++ S II+ ++ +PY++ FD + N L + F+ S+ LNSA NP+IY F++ P R ++ Q ++ F+ Sbjct: 56 LWVLFVFTIVGNSVVLFSTWRRKKKSRMTF-----FVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTL----IIFG--KRTL---SNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIK-------------------SKTYETVISNCSDGKLCSSYN-----------------RGLISKAKIKAIKYSIIIILAFICCWSPYFL---------FDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFR 354
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Match: NPSR1 (neuropeptide S receptor 1 [Source:HGNC Symbol;Acc:HGNC:23631]) HSP 1 Score: 73.1738 bits (178), Expect = 1.510e-13 Identity = 78/352 (22.16%), Postives = 156/352 (44.32%), Query Frame = 1 Query: 85 LLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV----ETRVYPFVCII--LAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI-------LNSAFNPIIYGYFNNLWFLPPRIRKYQK 1095 L F+ ++VGN V L +R++++ +F + L I D ++ +LT+ W T + +++C+++++ + + +STY++ ++ IDR I+ + +K + ++ WSLS +FSIP + ++ G K+ N E++ + ++ P++ I+ L + +PL +I YG ++ TI + S + +S L N R +S+AK K++ S II+ ++ +PY++ FD + N L + F+ S+ LNSA NP+IY F++ P R+ + ++ Sbjct: 56 LWVLFVFTIVGNSVVLFSTWRRKKKSRMTF-----FVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTL----IIFG--KRTL---SNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIK-------------------SKTYETVISNCSDGKLCSSYN-----------------RGLISKAKIKAIKYSIIIILAFICCWSPYFL---------FDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCRVIRLRQ 348
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: gnrr-1 (GoNadotropin-Releasing hormone Receptor (GnRHR) related [Source:UniProtKB/TrEMBL;Acc:H1ZUW9]) HSP 1 Score: 88.5817 bits (218), Expect = 4.728e-19 Identity = 83/331 (25.08%), Postives = 155/331 (46.83%), Query Frame = 1 Query: 88 LTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRV---YPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 L FI++ VGN+ +FL+ R Q + + + L+LH+ IA L VT++ + E + N W+ G+V+C++ KF + S ++ I +DR I +R+R+ +MV W++S + S PQ+ L K P + QC + + V + V II ++ PL V + CY I+ I ++ +++G EKE++ + ++ L ++ + L +AK ++L ++ I++ ++ TPY ++ FL L D I ++ + + ++LNSA +P +YGYF+ Sbjct: 28 LALFILAFVGNVT--MFLILCRNQLVK-VRRVHSLLLHMNIAHLLVTLVVMPKEILHNYMVAWFAGDVMCRICKFFDVFAISLSMNVLICITLDRFYSIFFPLYAMRARKSVQRMVSF----AWTISFVTSAPQLYLFKTATHPCFDWYTQCVSKNFIGELSNDVVFFFSIVNIIQVYIAPLFVTVVCYSLILWRISRKSKLVG-------------------------------EKESE-----KSSELLLRRNGQNNLEKAKSRTLKMTFVIVLAFIFCWTPYSILMFLHFLRHTDWIPK----DIRKFIYAFAVLNSAISPYLYGYFS 311
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: gnrr-1 (GoNadotropin-Releasing hormone Receptor (GnRHR) related [Source:UniProtKB/TrEMBL;Acc:H1ZUW9]) HSP 1 Score: 88.5817 bits (218), Expect = 5.064e-19 Identity = 83/331 (25.08%), Postives = 155/331 (46.83%), Query Frame = 1 Query: 88 LTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRV---YPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 L FI++ VGN+ +FL+ R Q + + + L+LH+ IA L VT++ + E + N W+ G+V+C++ KF + S ++ I +DR I +R+R+ +MV W++S + S PQ+ L K P + QC + + V + V II ++ PL V + CY I+ I ++ +++G EKE++ + ++ L ++ + L +AK ++L ++ I++ ++ TPY ++ FL L D I ++ + + ++LNSA +P +YGYF+ Sbjct: 28 LALFILAFVGNVT--MFLILCRNQLVK-VRRVHSLLLHMNIAHLLVTLVVMPKEILHNYMVAWFAGDVMCRICKFFDVFAISLSMNVLICITLDRFYSIFFPLYAMRARKSVQRMVSF----AWTISFVTSAPQLYLFKTATHPCFDWYTQCVSKNFIGELSNDVVFFFSIVNIIQVYIAPLFVTVVCYSLILWRISRKSKLVG-------------------------------EKESE-----KSSELLLRRNGQNNLEKAKSRTLKMTFVIVLAFIFCWTPYSILMFLHFLRHTDWIPK----DIRKFIYAFAVLNSAISPYLYGYFS 311
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: gnrr-5 (GoNadotropin-Releasing hormone Receptor (GnRHR) related [Source:UniProtKB/TrEMBL;Acc:O44536]) HSP 1 Score: 69.707 bits (169), Expect = 1.051e-12 Identity = 55/175 (31.43%), Postives = 89/175 (50.86%), Query Frame = 1 Query: 67 KIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLIL---HLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRV--QVIIRSRRLSDKMVVIC---LITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRV 564 +IK+ + + + IV +G + L+ L + R S++ K ++++L L +ADL L++ + IW +T QWYGGE LC+ F SF ++++IA I IDRV I S K + C L W L+ + S+PQ + P++ +F QC I M E R+ Sbjct: 30 RIKIEVCI-YVIVFFIGGPLNLMALSRSLRAFSRTHKAKSQILLLRITLNLADLMTLFLYVPKQIIWLITYQWYGGEFLCRACAFFSTFSFYLNSFVIACIAIDRVFGAYNISSLNAHRKAYIRCRNLLGCGWVLAFLLSLPQAVVFTT-TSPYENIDFKQCATIFMIFLHEKRI 202
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8]) HSP 1 Score: 69.3218 bits (168), Expect = 1.209e-12 Identity = 54/208 (25.96%), Postives = 99/208 (47.60%), Query Frame = 1 Query: 37 DPMPNFDLHSKIKVT---ILLTFFIVSVVGNIVTLIFLLKRRR-QTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIP---QMKLNKV--LLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCY 627 D P+ + VT + L F++ ++GN L +K R+ QT Q N IL+LC +++ + + L I N+ QW+ +CKLI + S ST+ ++ I +DR +++R ++LS + ++ + +W +S + +P M + K+ L G + E + + + Y F+ +I FL P A + CY Sbjct: 14 DKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQ-----NIFILNLCASNVLMCLTSLPITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRYNLVVRPHKQKLSSRSAMMIALLIWVISVVVCMPYGWYMDVEKLNGLCGEYCSEHWPLAEVR-------KGYTFLVLITQFLFPFATMAFCY 209
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8]) HSP 1 Score: 68.9366 bits (167), Expect = 1.503e-12 Identity = 54/208 (25.96%), Postives = 99/208 (47.60%), Query Frame = 1 Query: 37 DPMPNFDLHSKIKVT---ILLTFFIVSVVGNIVTLIFLLKRRR-QTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIP---QMKLNKV--LLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCY 627 D P+ + VT + L F++ ++GN L +K R+ QT Q N IL+LC +++ + + L I N+ QW+ +CKLI + S ST+ ++ I +DR +++R ++LS + ++ + +W +S + +P M + K+ L G + E + + + Y F+ +I FL P A + CY Sbjct: 39 DKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQ-----NIFILNLCASNVLMCLTSLPITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRYNLVVRPHKQKLSSRSAMMIALLIWVISVVVCMPYGWYMDVEKLNGLCGEYCSEHWPLAEVR-------KGYTFLVLITQFLFPFATMAFCY 234
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: CrzR (gene:FBgn0036278 transcript:FBtr0075989) HSP 1 Score: 110.538 bits (275), Expect = 6.433e-26 Identity = 100/353 (28.33%), Postives = 163/353 (46.18%), Query Frame = 1 Query: 37 DPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK---RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDR---VQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV-ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYW--MVYFL-----QHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 D P +KV +L + S++GN++T+ + K RR + ++ L+ HL IAD+ VT ++ E W T QW E+ CKL+K + S STY++ IG+DR V+ ++S ++ + + L + LS + S+PQ + V GP+ +EFYQC + + ++Y ++ FLLPL ++ G Y ST +T+S+SEK K + P + +++ + +AK KSL IS III +L TPY+ M+ F+ + LG D+L F+ + NS NP+IYG F+ Sbjct: 109 DHAPQLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCHRL-LGGTYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTADWQEQMYATFTLVFTFLLPLCILFGTY------------------------------MSTFRTISSSEKMFQGSKLANYSTAKLPTQT----NRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMMIMFMFLNPDKRLG----------DDLQDAIFFFGMSNSLVNPLIYGAFH 416
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: CrzR (gene:FBgn0036278 transcript:FBtr0330069) HSP 1 Score: 110.153 bits (274), Expect = 9.039e-26 Identity = 100/353 (28.33%), Postives = 163/353 (46.18%), Query Frame = 1 Query: 37 DPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK---RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDR---VQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV-ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYW--MVYFL-----QHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 D P +KV +L + S++GN++T+ + K RR + ++ L+ HL IAD+ VT ++ E W T QW E+ CKL+K + S STY++ IG+DR V+ ++S ++ + + L + LS + S+PQ + V GP+ +EFYQC + + ++Y ++ FLLPL ++ G Y ST +T+S+SEK K + P + +++ + +AK KSL IS III +L TPY+ M+ F+ + LG D+L F+ + NS NP+IYG F+ Sbjct: 109 DHAPQLSRSGLLKVYVLAVMALFSLLGNLLTIWNIYKTRISRRNSRHTWSAIYSLMFHLSIADVLVTWFCIIGEAAWCYTVQWLANELTCKLVKLFQMFSLYLSTYVLVLIGVDRWIAVKYPMKSLNMAKRCHRL-LGGTYILSLVLSLPQFFIFHVARGPFVEEFYQCVTHGFYTADWQEQMYATFTLVFTFLLPLCILFGTY------------------------------MSTFRTISSSEKMFQGSKLANYSTAKLPTQT----NRQRLIHKAKMKSLRISVVIIIAFLICWTPYYVMMIMFMFLNPDKRLG----------DDLQDAIFFFGMSNSLVNPLIYGAFH 416
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: AkhR (gene:FBgn0025595 transcript:FBtr0332331) HSP 1 Score: 95.9005 bits (237), Expect = 2.488e-21 Identity = 65/241 (26.97%), Postives = 115/241 (47.72%), Query Frame = 1 Query: 52 FDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG---FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGL 762 F+ ++ +T+ F++S +GN L L KRR +G + +++HL IADL VT+L + E +W T QW +++C+L+ F R S+Y++ I +DR I++ + S I L W S + SIPQ L + P ++QC +S + ++Y + + PL + + CYG I + I ++ Q + L ++ + S + LS ++K L Sbjct: 34 FNDGHRLSITVYSILFVISTIGNSTVLYLLTKRR------LRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRV------LKDVIAERFRRSNDDVLSRAKKRTL 262
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: AkhR (gene:FBgn0025595 transcript:FBtr0079309) HSP 1 Score: 95.9005 bits (237), Expect = 2.488e-21 Identity = 65/241 (26.97%), Postives = 115/241 (47.72%), Query Frame = 1 Query: 52 FDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG---FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGL 762 F+ ++ +T+ F++S +GN L L KRR +G + +++HL IADL VT+L + E +W T QW +++C+L+ F R S+Y++ I +DR I++ + S I L W S + SIPQ L + P ++QC +S + ++Y + + PL + + CYG I + I ++ Q + L ++ + S + LS ++K L Sbjct: 34 FNDGHRLSITVYSILFVISTIGNSTVLYLLTKRR------LRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRV------LKDVIAERFRRSNDDVLSRAKKRTL 262
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Match: AkhR (gene:FBgn0025595 transcript:FBtr0079308) HSP 1 Score: 95.9005 bits (237), Expect = 2.488e-21 Identity = 65/241 (26.97%), Postives = 115/241 (47.72%), Query Frame = 1 Query: 52 FDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG---FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGL 762 F+ ++ +T+ F++S +GN L L KRR +G + +++HL IADL VT+L + E +W T QW +++C+L+ F R S+Y++ I +DR I++ + S I L W S + SIPQ L + P ++QC +S + ++Y + + PL + + CYG I + I ++ Q + L ++ + S + LS ++K L Sbjct: 34 FNDGHRLSITVYSILFVISTIGNSTVLYLLTKRR------LRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRV------LKDVIAERFRRSNDDVLSRAKKRTL 262
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr4 (gonadotropin releasing hormone receptor 4 [Source:ZFIN;Acc:ZDB-GENE-050419-76]) HSP 1 Score: 97.4413 bits (241), Expect = 8.902e-22 Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F + +K++V I T VS V N+ L ++ S LI++L +ADL VT + + + WN+T QW G++ C+L+ F + ++ S ++ I +DR I+ + + K I L W++S + S+PQM L + F QC R +K + ET ++ F+C+ FL+PLA+++ CY I++ I ++ G +S +KE + + + +A+ ++L +S I+ +++ TPY+++ Y+ + +T+ +S L+H F + N+ +PI YG F Sbjct: 41 LPTFSMAAKVRVIITFTLCAVSAVCNLGVLWAASTNNKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWLAGDLACRLLMFLKLVAMYSCAFVTVVISLDRQSAILNPLAINKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTITVPANFTQCTTRGSFVKHWQETIYNMFTFICL---FLIPLAIMICCYTRILVEISRRMTK-GNIS----------------------------------------SKEVHLRRSHSNIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLPEDLEETVSHS----LTHMLFIFGLFNAILDPITYGLF 333
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr4 (gonadotropin releasing hormone receptor 4 [Source:ZFIN;Acc:ZDB-GENE-050419-76]) HSP 1 Score: 97.4413 bits (241), Expect = 8.902e-22 Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F + +K++V I T VS V N+ L ++ S LI++L +ADL VT + + + WN+T QW G++ C+L+ F + ++ S ++ I +DR I+ + + K I L W++S + S+PQM L + F QC R +K + ET ++ F+C+ FL+PLA+++ CY I++ I ++ G +S +KE + + + +A+ ++L +S I+ +++ TPY+++ Y+ + +T+ +S L+H F + N+ +PI YG F Sbjct: 41 LPTFSMAAKVRVIITFTLCAVSAVCNLGVLWAASTNNKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWLAGDLACRLLMFLKLVAMYSCAFVTVVISLDRQSAILNPLAINKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTITVPANFTQCTTRGSFVKHWQETIYNMFTFICL---FLIPLAIMICCYTRILVEISRRMTK-GNIS----------------------------------------SKEVHLRRSHSNIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLPEDLEETVSHS----LTHMLFIFGLFNAILDPITYGLF 333
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr4 (gonadotropin releasing hormone receptor 4 [Source:ZFIN;Acc:ZDB-GENE-050419-76]) HSP 1 Score: 97.4413 bits (241), Expect = 8.902e-22 Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F + +K++V I T VS V N+ L ++ S LI++L +ADL VT + + + WN+T QW G++ C+L+ F + ++ S ++ I +DR I+ + + K I L W++S + S+PQM L + F QC R +K + ET ++ F+C+ FL+PLA+++ CY I++ I ++ G +S +KE + + + +A+ ++L +S I+ +++ TPY+++ Y+ + +T+ +S L+H F + N+ +PI YG F Sbjct: 41 LPTFSMAAKVRVIITFTLCAVSAVCNLGVLWAASTNNKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWLAGDLACRLLMFLKLVAMYSCAFVTVVISLDRQSAILNPLAINKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTITVPANFTQCTTRGSFVKHWQETIYNMFTFICL---FLIPLAIMICCYTRILVEISRRMTK-GNIS----------------------------------------SKEVHLRRSHSNIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLPEDLEETVSHS----LTHMLFIFGLFNAILDPITYGLF 333
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: avpr1ab (arginine vasopressin receptor 1Ab [Source:ZFIN;Acc:ZDB-GENE-041210-105]) HSP 1 Score: 94.7449 bits (234), Expect = 6.552e-21 Identity = 89/357 (24.93%), Postives = 166/357 (46.50%), Query Frame = 1 Query: 25 NYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQ---MKLNKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSI----LNSAFNPIIYGYFNN 1056 N +TDP + +K+++T+L F+V+VVGN+ L+ + ++++S+ + I HL +ADL V +L + W +T ++YG + LC+++K + L +STY++ + +DR I +++ + + I + + W S + S PQ L+++ G + Y C F+E R Y + FL+P+ +++ CYGFI +I K ++ T + + + K+G+ K + S +SRAK +++ ++ I++ Y+ P++ V Q V+D N D+ + LS LNS NP IY F+ Sbjct: 11 NNTTDPFGRNEDVAKMEITVLSVTFLVAVVGNLCVLLAMHNTKKKSSR----MHLFIKHLSLADLVVAFFQVLPQLCWEITYRFYGPDFLCRIVKHLQVLGMFASTYMMVMMTLDRYIAICHPLKTLQQPTRRAYIMICSTWLCSLLLSTPQYFIFSLSEIQNG---SDVYDC----WGHFIEPWGIRAYITWITVGIFLIPVVILMICYGFICHSIWKNFKC------------------KTKRGAAHNPKSGMIGKAS--------------VSSVTIISRAKLRTVKMTFVIVLAYIVCWAPFFTV---QMWSVWDE--NFSWDDSENAAVTLSALLASLNSCCNPWIYMLFSG 319
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: gnrhr2 (gonadotropin releasing hormone receptor 2 [Source:ZFIN;Acc:ZDB-GENE-090128-3]) HSP 1 Score: 93.2041 bits (230), Expect = 2.445e-20 Identity = 91/364 (25.00%), Postives = 163/364 (44.78%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVV--ICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQI 1116 +P F S+++VT+ L +S N+ L +R+ S +I +L ADL VT + + T+ +WN+T QW G++ C+ + F + ++ S ++ I +DR I+ ++ M + L W++S + SIPQ+ + V+ K+F QC S + Y FLLPL +++ CY I+ I K+ +TE L NK L +SK + +A+ ++L ++ I+++++ TPY+M+ Y+ G+ +T+ S LSH F +LN+ +PIIYG F R R+ ++ + F++ Sbjct: 37 LPRFTAASQVRVTLTLVLCALSACCNLAVLYSANNNQRKRSH----VRLIITNLAAADLLVTFVVMPTDAVWNITLQWRAGDLACRTLMFLKLVAMYSCAFVTVVISLDRQAAILNPLSINKAMRRNKVLLGVAWTMSVVLSIPQVFVFHVVEIDSPKQFVQCTTYGSFSSRWQETFYNMFTFTFLFLLPLFIMISCYTRILFEISKK----------------------------------MTEDR------LLSNKVQLRRSKNN-IPKARMRTLKMTVVIVLSFMVCWTPYYMLGLWYWFSPAGLEETVSQS----LSHILFIFGLLNACLDPIIYGLFTVPLCRGMRHRQREQNIVAFEL 351
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: nrg3 (neuregulin 3 [Source:Xenbase;Acc:XB-GENE-984146]) HSP 1 Score: 99.7525 bits (247), Expect = 1.460e-22 Identity = 88/348 (25.29%), Postives = 155/348 (44.54%), Query Frame = 1 Query: 37 DP--MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV---ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 DP P F L +K++V + FF+++ N+ L + +R ++ LIL L +ADL VT L + + +WN+ QWY GE+ CK++ FG+ + S+ ++ I +DR I+ S + + I L T W S + + PQ+ L ++ P F QC SF + Y F+ PL V++ CY I+ I KQ M+H K L +SK +S+A+ K+L ++ I+++++ TPY+++ Y+ Q ++N + L+H F +L++ +P++YG + Sbjct: 29 DPWTEPTFTLAAKVRVGVTCCFFLIASFSNVAVLCSISGKRCKSH-----LRVLILSLSVADLLVTFLVMPLDALWNVMVQWYAGELSCKVLNFGKLFAMYSAALVLVVISLDRHWAILYPLSFTSAGQRNRIMLWTAWITSLLLASPQLFLFRLRTAP-GVNFTQCAT--HGSFTQHWQETAYNMFTFCTLFVTPLVVMIVCYTRILWEIGKQ---------------MKH-------------------------------KNELARSKNDLISKARLKTLKMTLVIVVSFMVCWTPYYLLGLWYWFQ-----PEMINQTPEYLNHSLFLFGLLHTCTDPLVYGLY 317
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: ccbe1 (collagen and calcium binding EGF domains 1 [Source:Xenbase;Acc:XB-GENE-920172]) HSP 1 Score: 97.0561 bits (240), Expect = 1.620e-21 Identity = 90/345 (26.09%), Postives = 152/345 (44.06%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDE-----LSHWFFWLSILNSAFNPIIYGYF 1050 +P F +K +V I F +S N+ + R+ + LIL+L ADL VT + + + IWN+T QW G++ C+++ F + LS S ++ I IDR I+ +S+ K I L W +S + S+PQ+ L + + F QC R + + ET VY V + FLLPL +++ CY I+I I ++ K L+ KE YL +K + +A+ ++L +S I+ +++ TPY++ LG++ ++E L+H F ++N+ +PI YG F Sbjct: 44 LPTFSPAAKARVIITFVIFALSAFCNLAVVWASTNTSRKKRSHVR---ILILNLTTADLLVTFIVMPLDAIWNITVQWQAGDLACRILMFLKLLSMYSCAFVTVVISIDRQSAILNPLGISEAKKRNKIMLSVAWLMSILLSLPQLFLFHTVTITEPQNFTQCTTRGSFQEHWQET-VYNMVSFVCLFLLPLLIMISCYSRILIEISRRM-----------------------------SKGALSSKE----VYLRRSKN--------NIPKARMRTLKMSIVIVSSFIICWTPYYL------LGLWYWFYPEAMEERVSQSLTHILFIFGLVNACLDPITYGLF 337
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: gnrhr (gonadotropin releasing hormone receptor [Source:NCBI gene;Acc:100135417]) HSP 1 Score: 94.7449 bits (234), Expect = 1.076e-20 Identity = 87/356 (24.44%), Postives = 157/356 (44.10%), Query Frame = 1 Query: 13 VTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKL-DELSHWFFWLSILNSAFNPIIYGYFN 1053 +T+ N +P F +KI+V I F+ S N+ L + + R+ S LI++L ADL +T++ + + +WN+T QWY G++ C+++ F + + SS ++ I +DR ++ + D K I L WSLS + +IPQ+ + + F QC + ++ + +Y FLLPL +++ CY I++ I +H +S++ L N + RA+ ++L +S I++T++ TPY++ LG++ + + K+ LSH F +LN+ +PIIYG F Sbjct: 30 ITLLNDKAFVLPIFSTAAKIRVAITCILFVFSTCFNVAALWTITYKYRKKSH----IRILIINLVAADLFITLVVMPLDAVWNVTLQWYAGDLACRVLMFLKLAAMYSSAFVTVVISLDRQAAVLNPLGIRDAKKKNKIMLCVAWSLSYLLAIPQLFVFHTVSRSEPVHFVQCATVGSFQAHWQETIYNMFTFFCLFLLPLLIMVFCYARILMEI----------------------THKMKAACVSSKEIDLRRSSNN-------------------IPRARMRTLKMSLVIVLTFIVCWTPYYL------LGIWYWFSPEMLTKEKVPPSLSHILFLFGLLNTCLDPIIYGLFT 334
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: AVPR1A (arginine vasopressin receptor 1A [Source:NCBI gene;Acc:100488869]) HSP 1 Score: 86.6557 bits (213), Expect = 5.724e-18 Identity = 88/360 (24.44%), Postives = 158/360 (43.89%), Query Frame = 1 Query: 4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWK-KEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVN--SKLDELSHWFFWLSILNSAFNPIIYGYFNN 1056 N + + + DP + +KI++ IL F+ +V+GN LI L K +++TS+ + I HL +ADL+V +L + W +T ++ G ++LC+++K + +S Y++ + DR I +++ + K + +I+ W +S + SIPQ + P E Y C F++ R Y F++P+A++ CYGFI I + Q K ++ ++ LSTS + T +SRAK +++ ++ I+ Y+ P+++V Q V+D D + L LNS NP IY +F+ Sbjct: 30 NSSSSQIDPTADPYVRNEALAKIEIAILAIIFVAAVLGNCSVLIGLYKSKKKTSR----MHLFIKHLSLADLAVAFFQVLPQLCWEVTYRFRGPDILCRIVKHLQVFGMFASAYMLVVMTADRYIAICHPLKTLQQPTKRSYVMIISAWIISFLLSIPQYFI--FSFSPVNGSEVYDC----WAHFIQPWGARAYITWMTASIFVVPVAILTTCYGFICYNIWRNIQCKTKRE--------ENEGRKSHGLLSTSVSSVKT------------------------ISRAKIRTVKMTLVIVTAYILCWAPFFIV---QMRSVWDKNFEWTDSEDIATTVTALLGSLNSCCNPWIYMFFSG 344
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: AVPR1B (arginine vasopressin receptor 1B [Source:NCBI gene;Acc:100487856]) HSP 1 Score: 84.3445 bits (207), Expect = 3.374e-17 Identity = 91/372 (24.46%), Postives = 180/372 (48.39%), Query Frame = 1 Query: 25 NYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVC-------IILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFF----WLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKP 1098 NY TDP N DL +K +V +L +++ N++ L + +RR++ ++ + I+HL DL+V + +L + IW++T ++ G ++LC+ +K+ + +S +STY++ + IDR + +++ + K + + W LS I S+PQ+ + + KE Q + + + + R YP+ + F +P+ ++L CY I I K + GK+ + +G+ ++E+ + P++ S R +SRAK +++ ++ I+++Y+ TP++ V Q V+D NS ++ + + F L+ L+S NP IY +N+ P R +P Sbjct: 19 NY-TDPR-NEDL-AKAEVALLGAILVITTGSNLIVLFAIYQRRKKMTR----MHLFIVHLTFTDLAVALFQILPQMIWDITFRFIGSDILCRAVKYTQVMSMFASTYMLMMMTIDRYIAVCHPLKTLQQPSKQAYLMIGGTWILSCILSLPQIFIFSM------KEISQGAGV-IDCWADFR-YPWGAKAYITWITVSIFFVPVGILLLCYSLICCEICKNLK--GKM-----------------------QTSGVGQRESN--GQVVPSR---VSSIRT-ISRAKIRTVKMTFVIVLSYILCWTPFFSV---QMWSVWDE--NSPDEDSTDFAFTITMLLASLSSCSNPWIYMCYNS----PQLCRGTSRP 335
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Gnrhr (gonadotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:95790]) HSP 1 Score: 100.523 bits (249), Expect = 3.087e-23 Identity = 87/353 (24.65%), Postives = 161/353 (45.61%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK--RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL---GPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 +P + KI+VT+ F++S N L+ L K ++R+ + L+ HL +A+L T++ + + +WN+T QWY GE LCK++ + + S + +++ I +DR I + + +L M+ + W LS +F+ PQ+ + +++ G F QC + + Y F F++PL ++L C K+ F L+ +L Q +P K L QSK + RA+ ++L ++ + +++ TPY++ LG+ FD ++N + ++H+FF + LN F+P+IYGYF+ Sbjct: 28 LPTLTVSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITQPLAVQSNSKLEQSMISL----AWILSIVFAGPQLYIFRMIYLADGSGPTVFSQCVTHCSFPQWWHQAFYNFFTFGCLFIIPLLIMLICN--------------AKIIFALTRVLHQ-----------------------------DPRKLQLNQSKNN-IPRARLRTLKMTVAFATSFVVCWTPYYV------LGIWYWFDPEMLNRVSEPVNHFFFLFAFLNPCFDPLIYGYFS 326
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Npsr1 (neuropeptide S receptor 1 [Source:MGI Symbol;Acc:MGI:2441738]) HSP 1 Score: 84.3445 bits (207), Expect = 1.894e-17 Identity = 83/357 (23.25%), Postives = 162/357 (45.38%), Query Frame = 1 Query: 85 LLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV----ETRVYPFVCII--LAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFW------LSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQ 1113 L F+V++VGN V L +R+R++ +F + L I D ++ +LT+ IW T + +++C+++++ + + +STY++ ++ IDR I+ + +K + + WSLS +FSIP + ++ G K+ N E++ + ++ P++ I+ L + +PLA+I YG ++ TI M+ +H T +S L N R +S+AK K++ S II+ ++ +PY++ L + V L + F+ L LNSA NP+IY F++ P ++++ Q ++ ++ Sbjct: 56 LWVLFVVTIVGNSVVLFSTCRRKRKSRMTF-----FVTQLAITDSFTGLINILTDIIWRFTGDFMAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQAKVLIGIAWSLSFLFSIPTL----IIFG--KRTL---SNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLAIISVIYGLVIRTI-----------------WMKSKTHET--VISNCSDGKLCCSYN-----------------RGLISKAKIKAIKYSIVIILAFICCWSPYFLFDILDNFNV--------LPDTKERFYASVIIQNLPALNSAINPLIYCIFSSSICSPCKMQRSQDSRMTYR 354
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Avpr1a (arginine vasopressin receptor 1A [Source:MGI Symbol;Acc:MGI:1859216]) HSP 1 Score: 81.6481 bits (200), Expect = 2.268e-16 Identity = 85/345 (24.64%), Postives = 158/345 (45.80%), Query Frame = 1 Query: 64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMK----SFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKA--GLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDT--IVNSKLDELSHWFFWLSILNSAFNPIIYGYFNN 1056 +K++VT+L F+V+V+GN L+ L + R+TS+ + I HL +ADL+V +L + W++T ++ G + LC+++K + + +S+Y++ + DR + +++ + + + + W LS + SIPQ + V+ EF + + +F+ TR Y F++P+ ++ CYGFI I + + KT S K G E F++ L S +SRAK +++ ++ I+ Y+ TP+++V Q V+DT + + + L+ LNS NP IY +F+ Sbjct: 51 AKLEVTVLAVIFVVAVLGNSSVLLALHRTPRKTSR----MHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGPDWLCRVVKHLQVFAMFASSYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAASWGLSFVLSIPQYFIFSVI------EFEVNNGTKAQDCWATFIPPWGTRAYVTWMTSGVFVVPVIILGTCYGFICYHIWRNVR---------------------GKTASRQSKGGKGSGEAAGPFHKGLLVTPCV---SSVKSISRAKIRTVKMTFVIVSAYILCWTPFFIV---QMWSVWDTNFVWTDSENPSTTITALLASLNSCCNPWIYMFFSG 358
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Gnrhr (gonadotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:95790]) HSP 1 Score: 77.7962 bits (190), Expect = 9.298e-16 Identity = 54/216 (25.00%), Postives = 104/216 (48.15%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK--RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL---GPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILK 654 +P + KI+VT+ F++S N L+ L K ++R+ + L+ HL +A+L T++ + + +WN+T QWY GE LCK++ + + S + +++ I +DR I + + +L M+ + W LS +F+ PQ+ + +++ G F QC + + Y F F++PL ++L C I+ + + Sbjct: 28 LPTLTVSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITQPLAVQSNSKLEQSMISL----AWILSIVFAGPQLYIFRMIYLADGSGPTVFSQCVTHCSFPQWWHQAFYNFFTFGCLFIIPLLIMLICNAKIIFALTR 239
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Oxtr (oxytocin receptor [Source:MGI Symbol;Acc:MGI:109147]) HSP 1 Score: 77.7962 bits (190), Expect = 3.211e-15 Identity = 58/221 (26.24%), Postives = 114/221 (51.58%), Query Frame = 1 Query: 25 NYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRS-RRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQM 666 N + P + ++++V +L +++ GN L+ L R + S+ F F K HL IADL V + +L + +W++T ++YG ++LC+L+K+ + + +STYL+ + +DR I +RS RR +D++ V + W + S+PQ+ L +V G + C + ++ + + Y + +++P+ V+ CYG I I + ++ Sbjct: 26 NLTAGPPRRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFF-FMK---HLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAV---LATWLGCLVASVPQVHIFSLREVADG-----VFDCWAVFIQPW-GPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRL 233
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|Q8CH60|GNRHR_CAVPO (Gonadotropin-releasing hormone receptor OS=Cavia porcellus OX=10141 GN=GNRHR PE=2 SV=2) HSP 1 Score: 112.079 bits (279), Expect = 1.528e-26 Identity = 97/354 (27.40%), Postives = 164/354 (46.33%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG-----FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL---GPWKKE-FYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDE-LSHWFFWLSILNSAFNPIIYGYFN 1053 +P L KI+VT+ F+VS N FLLK ++ T + KG L+ HL +A+L T++ + + +WN+T QWY GE+LCK++ + + S + +++ I +DR I R +R+L M + W LS++ + PQ+ + K++ GP + E F QC + + Y F I F++PL ++L C K+ F L+ +L Q + NK L QSK + RA+ ++L ++ + +++ TPY Y L FD + ++ E ++H+FF + LN F+P+IYGYF+ Sbjct: 28 LPTLTLSGKIRVTVTFFLFLVSTTLNAS---FLLKLQKWTQKKEKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKILSYLKLFSMYAPAFMMVVISLDRSMAITRPLPVQSNRKLEQSMTGL----AWGLSSVLAGPQLYIFKMIHLENGPGQTEVFSQCVTHCSFPQWWHQAFYNFFTFICLFIIPLLIMLICN--------------AKIIFTLTQVLQQ-----------------------------DSNKLQLNQSKNN-IPRARLRTLKMTVAFAASFIVCWTPY---YVLGLWYWFDPGMLHRMSEPVNHFFFLFAFLNPCFDPLIYGYFS 327
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|P49922|GNRHR_PIG (Gonadotropin-releasing hormone receptor OS=Sus scrofa OX=9823 GN=GNRHR PE=2 SV=2) HSP 1 Score: 106.301 bits (264), Expect = 1.733e-24 Identity = 92/356 (25.84%), Postives = 162/356 (45.51%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK--RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVL----LGPWKKEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 +P L KI+VT+ F++S N L+ L K +R++ + L+ HL +A+L T++ + + +WN+T QWY GE LCK++ + + S + +++ I +DR I R + RL M+ + W LS+IF+ PQ+ + +++ + F QC + SF + Y F F++PL ++L C IM T+ + Q +P+ L QSK + RA+ ++L ++ + +++ TPY++ LG+ FD +VN D ++H+FF + LN F+P+IYGYF+ Sbjct: 28 LPTLTLSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQRKEKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLAVKSNSRLGRFMIGL----AWLLSSIFAGPQLYIFRMIHLADSSGQTEGFSQC--VTHGSFPQWWHQAFYNFFTFSCLFIIPLLIMLICNAKIMFTLTRVLQQ-------------------------------------------DPHNLQLNQSKNN-IPRARLRTLKMTVAFAASFIVCWTPYYV------LGIWYWFDPEMVNRVSDPVNHFFFLFAFLNPCFDPLIYGYFS 327
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|P30968|GNRHR_HUMAN (Gonadotropin-releasing hormone receptor OS=Homo sapiens OX=9606 GN=GNRHR PE=1 SV=1) HSP 1 Score: 103.605 bits (257), Expect = 1.504e-23 Identity = 94/353 (26.63%), Postives = 165/353 (46.74%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKG-----FNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL-SDKMVVICLITV-WSLSTIFSIPQMKLNKVL----LGPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 +P L KI+VT+ F++S N FLLK ++ T + KG L+ HL +A+L T++ + + +WN+T QWY GE+LCK++ + + S + +++ I +DR I R L S+ V ++ + W LS++F+ PQ+ + +++ K F QC + + Y F F++PL ++L C K+ F L+ +L Q +P++ L QSK + RA+ K+L ++ + ++ TPY++ LG+ FD ++N D ++H+FF + LN F+P+IYGYF+ Sbjct: 28 LPTLTLSGKIRVTVTFFLFLLSATFNAS---FLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICN--------------AKIIFTLTRVLHQ-----------------------------DPHELQLNQSKNN-IPRARLKTLKMTVAFATSFTVCWTPYYV------LGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFS 327
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|Q2V2K5|GNRHR_OCTVU (Gonadotropin-releasing hormone receptor OS=Octopus vulgaris OX=6645 GN=GNRHR PE=2 SV=1) HSP 1 Score: 104.375 bits (259), Expect = 2.580e-23 Identity = 97/350 (27.71%), Postives = 166/350 (47.43%), Query Frame = 1 Query: 25 NYSTDPMPN---FDLHSKIKVTILLTFFIVSVVGN--IVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKE-FYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 N ++ P+P+ FD K+ +L T F++S GN ++ IF ++ R T QS LIL+L IADL V+ +L + IW+ T +W G +CK++K+ STY+ +I +DR I+ SR + V I + W LS IFSIPQ + + +++ F+QCR+ + + ++Y +IL F++PL +++ Y I+ TI+K + Q H + +S + + + Q +L RA+ +S +S+ I+ ++ TPY++++ +D NS+ +FF L N NP+IYG F Sbjct: 15 NITSTPLPDAPRFDNVYVSKLCVLGTVFVISFFGNTLVIIQIFRIRGSRSTIQS------LILNLAIADLMVSFFNILMDIIWSATVEWLAGNTMCKIMKYLTVFGLHLSTYITVSIALDRCFAILSPMSRSKAPLRVRIMITMAWVLSAIFSIPQAVIFQEQRKMFRQGMFHQCRD-SYNALWQKQLYSASSLILLFVIPLIIMVTSYLLILKTIVKTSR--------------QFH----DTPISPTSMSCYSVNHGQIRTHL--------------FERARKRSSRMSAVIVAAFILCWTPYYIIFLGFAFFQWD---NSR---TVIYFFTLGTSNCMLNPLIYGAF 319
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|Q19PY9|GNRHR_BOSMU (Gonadotropin-releasing hormone receptor OS=Bos mutus grunniens OX=30521 GN=GNRHR PE=3 SV=1) HSP 1 Score: 102.834 bits (255), Expect = 2.851e-23 Identity = 90/353 (25.50%), Postives = 163/353 (46.18%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLK-----RRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLL----GPWKKEFYQC-RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGV---FD-TIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 +P L KI+VT+ F++S + N FLLK +R++ + L+ HL +A+L T++ + + +WN+T QWY GE+LCK++ + + S + +++ I +DR I + + + + K+ + W LS+IF+ PQ+ + ++ + F QC + + Y F F++PL +++ C K+ F L+ +L Q +P+K L QSK + RA+ ++L ++ + ++ TPY++ LG+ FD +VN D ++H+FF + LN FNP+IYGYF+ Sbjct: 28 LPTLTLSGKIRVTVTFFLFLLSTIFNTS---FLLKLQNWTQRKEKRKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITKPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGMIHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMVICN--------------AKIIFTLTRVLHQ-----------------------------DPHKLQLNQSKNN-IPRARLRTLKMTVAFATSFTVCWTPYYV------LGIWYWFDPDMVNRVSDPVNHFFFLFAFLNPCFNPLIYGYFS 327
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A291FE86 (Gonadotropin-releasing hormone receptor 1 OS=Platynereis dumerilii OX=6359 PE=2 SV=1) HSP 1 Score: 153.68 bits (387), Expect = 1.728e-38 Identity = 106/343 (30.90%), Postives = 169/343 (49.27%), Query Frame = 1 Query: 40 PMPNFDLHSKIKVTILLTFFIVSVVGNIVTLI--FLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEM-KSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 P P + S IK ++L T F++S+VGN TL+ F ++RRR T N LI+HL ADL VT L ++IW T QW G ++CKL+K+ + STY++ I IDR I+ SR + + V + +IT W LS IFS PQ + V GP+ +YQC + + ++Y + +L F++PL +++ Y I TI K+ + + K + S + + LS + P + LFQ +AK KSL +++ I++ ++ +PY++++ L T + +L S W F NS NP+IY F+ Sbjct: 72 PPPTANRMSTIKTSVLSTLFVISLVGNTATLVQMFRMRRRRST------INTLIMHLATADLIVTFFCFLADSIWVTTVQWLAGNIMCKLVKWLQVFGLYLSTYIVVIIAIDRAYAILDPMSRNKAPRRVRLMIITAWVLSAIFSAPQAYIFSVQRGPYSAPYYQCVTFGAYNARWQEQMYSIISALLMFIIPLIIMITAYMLIFTTIAKKSRDLKKGILIRSSCCISETEQAAADMLSQA-----------------PVRGELFQ-------KAKVKSLKMTTLIVLAFIICWSPYYVIF----LAYTFTDMTPQLKYASMWIFCFGTGNSLLNPLIYSAFH 380
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A1C6ZYI2 (Corazonin receptor OS=Crassostrea gigas OX=29159 PE=2 SV=1) HSP 1 Score: 149.443 bits (376), Expect = 4.296e-37 Identity = 107/343 (31.20%), Postives = 174/343 (50.73%), Query Frame = 1 Query: 31 STDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI-EMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 + PMP S +K +L+ F +S +GN TLI + + R++ S N LI++L +ADL VT + E +W +T QW G +CK+++F + L STY+ I +DR VII SR + + V I +I W LS +FSIPQ L V GP+K++FYQC +I S ++Y C+I+ F LPL +++ YG I TI ++ + G+ ++ S+S+++ E +G + + L +AK K+L +S I+I + PY++V+ G + ++ S + L+ ++ + NS NPIIYG F Sbjct: 51 TESPMPPTFQDSLVKTVVLILLFTISFIGNTATLIQMYRVRKRRST----INTLIVNLAVADLIVTFFCMAAEAVWALTVQWVAGVAMCKMLRFIQGTGLLVSTYITVVISLDRCCVIIDPISRNKAPQRVRIMIIMSWFLSALFSIPQALLFSVHRGPFKEDFYQCVDILGYPSPAYKKLYNIFCMIIQFFLPLTLMIIAYGLIFFTISRKSKEFGE---------PENVSNSSDQ----REHSGRS------------------HVRSGLLRKAKRKALRMSLFIVIAFFVCWLPYYVVFTGFAFGHWTSLDPSLMSGLT----FVGLTNSILNPIIYGAF 354
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: V4BCY4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_103088 PE=4 SV=1) HSP 1 Score: 145.206 bits (365), Expect = 5.995e-36 Identity = 108/362 (29.83%), Postives = 173/362 (47.79%), Query Frame = 1 Query: 46 PNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRS--RRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFV---ETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPR---IRKYQKPKII 1107 P FD + K + T F+++ +GN+ TLI + + R + S N LI++L I DL + E IW T QWYGG +CK+IKF + S STY+ IG+DR I+ R+ + V ++ W S +FSIPQ + V GP+K++FYQC + M S+ + VY +L F++PL +I YG I TI ++ + K + T +T S ++ + N L +AK KSL +S I++ ++ TPY++++ ++ I N ++ L W F+L + N+ NP+IYG F PR +R ++ KI+ Sbjct: 29 PTFDDIAMTKCIVFGTMFVIAFIGNVATLIQMYRMRHRKST----INTLIVNLAIGDLFIVCFCFPVEGIWAATVQWYGGTAMCKIIKFIQVFSLYLSTYVTVAIGLDRCVAILDPMRRKSAPTRVRTMIMLAWFFSALFSIPQAIIFNVRRGPFKEDFYQC--VTMGSYPNAWQEEVYSIASFLLMFVIPLVIIGTAYGLIFSTIARKSKEFIK-------------KNPTVRTTSYNDIQRGPVRSN-------------------LLRKAKRKSLRMSIVIVVVFVMCWTPYYVIFICLTFLDWEEI-NPRIYRLVLWLFFLGMSNAVMNPLIYGAFQICKVHTPRSVHLRAFRSHKIL 351
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A193KUK2 (GCR073 OS=Schmidtea mediterranea OX=79327 GN=gcr073 PE=2 SV=1) HSP 1 Score: 142.51 bits (358), Expect = 1.288e-34 Identity = 113/366 (30.87%), Postives = 187/366 (51.09%), Query Frame = 1 Query: 22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI---LKQYQMIGKLSFMLSPLLMQHHSHSTNK-------TLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELS-HWFFWLSI-------LNSAFNPIIYG 1044 N + +P+F+ ++ K L F +S++GN T+ F LK ++++ S++ ++I+ L AD+ V + F+LT+ IWN+ W GG LCKL+K G+ S STY+++ + +DR I + S + K+++ICL W S + +IPQ+ L GPWK FYQC + + ++ VYP V +L L+P+ +++ CY I+ TI K+Y+ ++ + H TN+ S S T N+ + ++ L K+ +SRAK K+ +S+ II +L PYW+ Y V T+ N++L + + W+S+ LNSAFNPIIYG Sbjct: 6 NNLTLPKIPSFNGYNLFKSVFFLVVFFISILGNTHTIFFTLKLQKRSKLSYRSLYRMIMQLAFADILVCLFFVLTQAIWNIFVSWRGGSFLCKLMKMGQAFSIYLSTYIMSLVSLDRAIAICKPIHHLHSWNRNIKIIIICL---WIYSFLLAIPQVLLFDAYRGPWKTVTFYQCTTSDNLNILQMYVYPLVYCVLILLIPIGILVTCYTVIIHTINVRSKEYEEHNSVTILFHQPKSDDCEHLTNQFPFYDDAKHSGSNNDNETIVINRISENSNNFQKLLSHKKQQLMSRAKIKTYRMSAIIISCFLLCWLPYWVYY------VLITLKNARLIKFTLGKNIWISVFIQSLASLNSAFNPIIYG 362
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Match: A0A3G9D4B1 (Gonadotropin-releasing hormone receptor OS=Mizuhopecten yessoensis OX=6573 GN=gnrhr PE=2 SV=1) HSP 1 Score: 140.198 bits (352), Expect = 1.502e-33 Identity = 112/399 (28.07%), Postives = 189/399 (47.37%), Query Frame = 1 Query: 31 STDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETR-VYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLV---LKHPLKVRRP 1209 ST P P F+ ++ +L F++S +GN TLI + + R++ S N LI++L IADL V + E W +T Q+ G +CK++++ + FL STY+ I +DR VI+ SR + + V + W LS +FS+PQ+ + VL GP+K++FYQC +I + + +Y C+ + F++PL +++ YG I TI ++ + N T S G + N L +AK K+L +S I+I ++ PY++++ G ++ + S + LS + + NS NPIIYG F ++ K +P+++ W+T + K N +I LLV K ++R P Sbjct: 68 STSP-PVFNDAYMVETIVLSALFLISFIGNTATLIQMYRMRKRRST----INTLIVNLAIADLIVAFFCMAAEAFWTVTIQFLAGNAMCKILRYIQVFGFLLSTYITVVISLDRCCVILDPISRNKAPQRVRFMIGVSWLLSALFSVPQLLVFSVLRGPFKEDFYQCVDIASYPHPQYKWMYNIFCLFVQFMIPLGIMIAAYGLIFCTISRKSK-----------------EFRGNDTTSNKNDLGRGQVRNN------------------LLKKAKRKALRMSIFIVIAFVVCWFPYYVLFTGNAFGQWEELSPSLMAGLST----MGLSNSMLNPIIYGAF--------QLCKVHRPRLV----WRTVVS--KPSGNDSIYLLVKEGEKASFRIRTP 408
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: gnrhr4 (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:103034933]) HSP 1 Score: 100.138 bits (248), Expect = 1.107e-22 Identity = 86/346 (24.86%), Postives = 152/346 (43.93%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV----YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F +K +V I T VS N+ L R+ S LI++L +ADL VT + + + WN+T QW G+ C+L+ F + ++ S ++ I +DR I+ +S+ K I L W++S + S+PQM + + F QC R +K + ET ++ FVC+ FLLPL +++ CY I++ I ++ G +S +KE + ++ +A+ ++L +S I+ +++ TPY+++ +FL D + + L+H F + N+ +PI YG F Sbjct: 40 LPTFSAAAKARVIITFTLCAVSAACNLAVLWAASTSTRRKSH----VRILIINLTVADLLVTFIVMPVDAAWNITVQWLAGDFACRLLMFLKLVAMYSCAFVTVVISLDRHSAILNPLAISEAKKKSKIMLSAAWAMSIVLSVPQMFIFHTVTITVPANFTQCTTRGSFVKHWQETLYNMFTFVCL---FLLPLVIMIFCYTRILLEISQRLSK-GNIS----------------------------------------SKEVHLRRSNNYIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLP-----DDLEETVSHSLTHMLFIFGLFNAILDPITYGLF 332
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: gnrhr4 (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:103034933]) HSP 1 Score: 100.138 bits (248), Expect = 1.132e-22 Identity = 86/346 (24.86%), Postives = 152/346 (43.93%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV----YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F +K +V I T VS N+ L R+ S LI++L +ADL VT + + + WN+T QW G+ C+L+ F + ++ S ++ I +DR I+ +S+ K I L W++S + S+PQM + + F QC R +K + ET ++ FVC+ FLLPL +++ CY I++ I ++ G +S +KE + ++ +A+ ++L +S I+ +++ TPY+++ +FL D + + L+H F + N+ +PI YG F Sbjct: 47 LPTFSAAAKARVIITFTLCAVSAACNLAVLWAASTSTRRKSH----VRILIINLTVADLLVTFIVMPVDAAWNITVQWLAGDFACRLLMFLKLVAMYSCAFVTVVISLDRHSAILNPLAISEAKKKSKIMLSAAWAMSIVLSVPQMFIFHTVTITVPANFTQCTTRGSFVKHWQETLYNMFTFVCL---FLLPLVIMIFCYTRILLEISQRLSK-GNIS----------------------------------------SKEVHLRRSNNYIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLP-----DDLEETVSHSLTHMLFIFGLFNAILDPITYGLF 339
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: ENSAMXT00000039545.1 (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:103037789]) HSP 1 Score: 98.5969 bits (244), Expect = 2.180e-22 Identity = 86/348 (24.71%), Postives = 158/348 (45.40%), Query Frame = 1 Query: 46 PNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFN 1053 P F ++ +V L F+ + V N+ LI + + R + S LI+ L +ADL +T + + + +WN+T QWYGG+ LCKL+ F + + +S +++ I +DR I+ + R + +M LI WSLS + PQ+ + + + + +F QC + SF E VY + +++PL V+ CY I+I I +Q +H KAG + L +S+ + +A+ K+L ++ I+++++ TPY+++ Y+ Q ++ + + H F LN+ +P+IYG + Sbjct: 36 PAFTRAAQFRVAATLVLFLFAAVSNLALLISVSRGRGRRLASH--LRPLIISLVVADLMMTFIVMPLDMVWNVTVQWYGGDGLCKLLSFLKLFAMQASAFILVVISLDRHHAILHPLDSLNAHRRNRRM----LILAWSLSLLLGSPQLFIFRTIKAE-RVDFTQC--VTHGSFRERWQETVYNMFHFVTLYVIPLLVMSCCYTHILIEINRQ----------------EH-----------KNKAG---------------ESCLRRSRTDMIPKARMKTLKMTIIIVMSFIVCWTPYYLLGIWYWFQ-----PEMLKVTPEYVHHLLFVFGNLNTCCDPVIYGLYT 327
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: gnrhr1 (gonadotropin releasing hormone receptor 1 [Source:ZFIN;Acc:ZDB-GENE-090128-2]) HSP 1 Score: 92.0485 bits (227), Expect = 3.924e-20 Identity = 81/346 (23.41%), Postives = 156/346 (45.09%), Query Frame = 1 Query: 46 PNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR------SRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIE--MKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMV---YFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 P F ++ +V L F+ + + N+ L+ + + R + S LI L +ADL +T + + + +WN+T QWY G+ +CKL+ F + + S+ +++ + +DR I+ + R + KM L+T W+LS + + PQ+ + + + +F QC K + ET Y + ++ PL V+ CY I++ I N+ ++ S+ G EP L +S + +A+ K+L ++ I+ +++ TPY+++ Y+ Q ++ + + H FF LN+ +P+IYG+F Sbjct: 31 PTFTTAARFRVVATLVLFVFAAISNLSVLLSVTRGRGRRLASH--LRPLIGSLALADLVMTFVVMPLDAVWNVTVQWYAGDAMCKLLCFLKLFAMHSAAFILVVVSLDRHHAILHPLDALDAGRRNRKM----LMTAWTLSVVLASPQLFIFRAIKAE-GVDFVQCATHGRFQKHWQET-AYNMFQFVTLYVFPLLVMSFCYTRILVEI--------------------------NRQMNRSKDKG------------EP---CLRRSGMDMIPKARMKTLKMTIIIVASFVICWTPYYLLGIWYWFQ-----PQMLQVIPEYVHHIFFVFGNLNTCCDPVIYGFF 322
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: oxtr (isotocin receptor [Source:NCBI gene;Acc:103033855]) HSP 1 Score: 87.0409 bits (214), Expect = 2.221e-18 Identity = 61/222 (27.48%), Postives = 114/222 (51.35%), Query Frame = 1 Query: 31 STDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRS-RRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVE---TRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQM 666 + +P+ + +K++V +L ++ GN+ L+ L R T + HL IADL V + +L + IW++T ++YG ++LC+L+K+ + + +STY++ + +DR + +RS RR +D++ V+C W LS IFS+PQ+ L +V G Y C FV+ + Y + +++P+ ++ CYG I I + ++ Sbjct: 35 TVNPLKRNEEVAKVEVAVLALVLFFALAGNLCVLLAL----RTTKHGPSRMYYFMKHLSIADLVVAVFQVLPQLIWDITFRFYGPDLLCRLVKYLQIVGMFASTYMLVLMSVDRCLAVCQPLRSLRRRTDRLYVLC---SWLLSLIFSVPQVGIFSLREVGAG-----VYDCWG----DFVQPWGAKAYITWISLTVYVVPVGILSACYGLISFKIWQNVRL 240
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010165.1 (pep scaffold:Pmarinus_7.0:GL493405:1402:3508:1 gene:ENSPMAG00000009199.1 transcript:ENSPMAT00000010165.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.1965 bits (217), Expect = 2.682e-20 Identity = 60/208 (28.85%), Postives = 103/208 (49.52%), Query Frame = 1 Query: 64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI-----IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQ 663 ++ +V FI + + N+ L + R+T + LI++L ADL +T + + + +W++TTQWY GE C+L+ F R L+ SS ++ I +DR I I + +K + L W LS + ++PQ+ L V K F QC + +FVE +Y + F+LPL +++ CY I++ I K+ + Sbjct: 51 TQFRVISTFALFIFAAISNLTVLCTISHNHRKTKSHVR---ILIVNLTTADLLITFIVMPLDAVWHITTQWYAGEFACRLLMFLRLLAMYSSAFITVVISLDRHSAILNPLGIGKAKAKNKTM---LSVAWVLSVLLAVPQLFLFHVKSPKGNKNFVQC--VTHGNFVEQWHHNLYYMFTFVFLFILPLFIMIFCYCRILLEISKRMR 250
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001380.1 (pep scaffold:Pmarinus_7.0:GL477135:197258:202768:-1 gene:ENSPMAG00000001242.1 transcript:ENSPMAT00000001380.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.5817 bits (218), Expect = 1.778e-19 Identity = 63/228 (27.63%), Postives = 113/228 (49.56%), Query Frame = 1 Query: 4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKL-------NKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQ 657 ++ T+ S + + +K+++ +L V++VGN+ L+ L+ R++TS+ + I+HL IADL V +L + IW +T ++ G + LC+ IK+ + L +STY++ +G+DR I +R+ R S K + W LS +FS+PQ + N ++ W EF + T+ Y F++P+ +++ CYG I I K Sbjct: 30 SINATLNGSSQHALDRNEEVAKVEIALLSIILFVAIVGNVCVLLALINTRKKTSR----MHLFIMHLSIADLVVAFFQVLPQLIWKITYRFNGSDFLCRAIKYLQILGMFASTYVLIMMGLDRYIAICHPLRTLRQSSKQSYQMIFVSWFLSMLFSLPQAFIFSMSEVENSGIIDCW-AEFIKPWG--------TKAYITWMTGSVFIIPVIILIWCYGMITFAIWKN 244
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010781.1 (pep scaffold:Pmarinus_7.0:GL479461:3925:14587:-1 gene:ENSPMAG00000009764.1 transcript:ENSPMAT00000010781.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 72.0182 bits (175), Expect = 3.037e-14 Identity = 90/353 (25.50%), Postives = 159/353 (45.04%), Query Frame = 1 Query: 22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHW--FFWLSILNSAFNPIIYGYFNN 1056 N S + + +K+++TIL +VVGN L+ LL +++TS+ + I+HL IADL V +L + IW +T ++ G ++LC+ +K+ + L +STY+ +IR+ + S + ++ W +S +FS+PQ L +V G Y C +FVE + Y + F+ P+AV+L CYG I I + M + + + ++T+ + ++ N +S+AK ++ ++ II+ Y+ TP+++V Q V+D S E S + L+ LNS NP IY +F+ Sbjct: 23 ANASESTLSRDEDLAKVEITILAIILCAAVVGNACVLLALLSTKKKTSR----MHLFIMHLSIADLVVAFFQVLPQLIWEVTFRFNGSDILCRTVKYLQILGMFASTYM-----------LIRTIQQSSTQSYMMILVSWLVSFLFSVPQAYIFSLREVQQG---TGVYDC----WAAFVEPWGLKAYVTWTAVAVFVAPVAVLLWCYGMITAEIWRN---------MRAKMERRGGRDGPVAPVATATASRVSSVRN--------------------ISKAKIRTTKMTFVIIVVYVFCWTPFFLV---QMWSVWD---GSAPFEGSAFTIVMLLASLNSCTNPWIYMFFSG 318
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: si:dkey-178o16.4 (si:dkey-178o16.4 [Source:ZFIN;Acc:ZDB-GENE-131127-163]) HSP 1 Score: 70.0922 bits (170), Expect = 1.161e-13 Identity = 39/141 (27.66%), Postives = 73/141 (51.77%), Query Frame = 1 Query: 64 SKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVII-----RSRRLSDKMVVICLITVWSLSTIFSIPQ 471 ++ +V +L F + +GN V L L +RR+ S+ + ++HLC+ADL V +L + W++T + + C+ IK+ + + +STY+I +DR Q + +R++ +C VW +S + S+PQ Sbjct: 23 ARAEVAVLFAMFACTTLGNSVLLTALYRRRKHASR----MHVFMVHLCLADLVVAFFQVLPQLAWDITDVFLASDFACRFIKYMQIVGMFASTYMIVGTTVDRYQAVCFPMVTFKKRMAYWNAPVC--AVWVVSLLLSVPQ 157
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008459.1 (pep scaffold:Pmarinus_7.0:GL478345:24256:33787:1 gene:ENSPMAG00000007650.1 transcript:ENSPMAT00000008459.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.4774 bits (171), Expect = 1.432e-13 Identity = 72/319 (22.57%), Postives = 131/319 (41.07%), Query Frame = 1 Query: 115 GNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQM---KLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIV--NSKLDELSHWFFWLSILNSAFNPIIYGYFNN 1056 GN L+ L + RR+ S+ N + HL +ADL+V +L + W++T ++ G + LC+L+K+ + + +STY++ +R R K + W+LS + S PQ+ L +V G + C + R Y + ++ P+ ++ CYG I++ I + ++ + + P Q S ++ S +SRAK +++ ++ II+ Y+ TP+ + +Q +D + D LS LNS NP IY F+ Sbjct: 62 GNGSVLLALSRTRRKASR----MNLFVKHLSVADLAVAAFQVLPQLSWDVTFRFRGPDALCRLVKYLQVVGMFASTYVL----------TLRRRGEPRKQAHAMVACAWALSALLSTPQVVIFSLREVEEG-----VFDCW-ADFGQPWGMRAYVTWITVSVYVAPVLILAACYGAILLEICRNLRLKTRGRYPKDPRGSQSQSPVCSRVSSVR-----------------------------CISRAKVRTIKMTLVIIVVYVVCWTPF---FVIQMWAAWDETAPDDDSSDPTYTIVMLLSSLNSCTNPWIYMSFSG 328
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO39861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8Q1]) HSP 1 Score: 66.6254 bits (161), Expect = 4.106e-12 Identity = 84/372 (22.58%), Postives = 158/372 (42.47%), Query Frame = 1 Query: 4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQC----RNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHST-------NKTLSTSEK----------AGLTEKENQFY-QYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSK---LDELSHWFFWLSILNSAFNPIIYG 1044 NL T +T D ++ T+ + SVVGN + + ++ + ++ L +L IA+L V+ +FLL I+ W G+ +C L + LS L T+ +A I I R VI K + ++ +W +T + P +K+++ P+ + Y C + SF R Y V +L ++LP+ +++ YG + + I + L+ + +HST N + SE AG + QF+ + + + + ++++ L + L + +II+ ++ PY + YFL++ FD + K + F ++ L SA +P+ YG Sbjct: 14 NLTSTEPASATTEYEESDEMRYLRFTLFGVISLASVVGNAIIIKSVISIPYKKPLTYT----LTTNLAIAEL-VSTIFLLMLVIYEEIKTWPFGDFMCHLTSPIQILSGLVVTWSMALISIHRFVVITSPGSQYIKKQELLMVLLWLAATAITFPLFMYSKMVMSPFDPDTYWCFVLFPGDSLSSFPSYRTYHMVRFMLNYILPIVIMIAAYGALGFRLKYHIAFIRTVHSELT--VPNSGTHSTGAVTVNGNTDIEASEPNNDNNNDVILAGTKDPSRQFHASFSQTSSDVVYEN---LLIDLESDLLRMIYAIILIFVVCYIPYQVFYFLEY---FDVVSYQKWRYFTVCRRYIFLITCLPSALHPLCYG 372
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO36138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJL3]) HSP 1 Score: 63.929 bits (154), Expect = 3.046e-11 Identity = 82/353 (23.23%), Postives = 148/353 (41.93%), Query Frame = 1 Query: 100 IVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRL--SDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNI----EMKSF--VETRVYPFVCIILAFLLPLAVILGCYGFIMITIL-------------------------KQYQMIGKLSFML-----SPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYG 1044 I S++GN V + + + + ++ L+ ++ +A+L T+L + + + W GE+LC +I + LS L +T +A I + R +V RR+ S K + +I++W+++ ++P + ++ P +K Y C + ++K F E R Y + F++P V++ YG + + + Q Q G +S L SP Q H N + ST E+A +E Q KR +S + L + II+ +L PY + + L++ GV + D + F L+ SA +PI YG Sbjct: 48 IASLLGNSVVIKTVFENSLRKPMTYY----LVSNMAVAELIGTVLVPFSYS-YQEIFHWPFGELLCHIIAPLQVLSVLVTTTSLAAIALHRYKVFTSPRRVRVSGKTITCTIISLWAIAFFITLPSFLYHSHVISPTQKGKYWCLELVPGDQLKDFPSPELRKYYMIRFFCNFVIPACVMMFSYGVVSLQLRFHRNRAVRDVEMETGSDRTRETSASTQPQQQGTVSMELHEVVRSPPHAQQPQH--NASNSTREQA---TRERA-------------QRKRQAISGLETDLLKMIYLIILIFLVCYFPYQIFFLLEYFGVMNYKNWQYFDITRIYVFLLTCFPSAIHPICYG 377
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO36453 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIH9]) HSP 1 Score: 60.4622 bits (145), Expect = 3.138e-10 Identity = 46/161 (28.57%), Postives = 83/161 (51.55%), Query Frame = 1 Query: 4 NLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTET-IWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRR--LSDKMVVICLITVWSLSTIFSIPQMK 477 +L T ++ +TDP+ + L + IK+T+ F+VS GN + I +LKR++ + + N IL+L +ADL++T + + + + M W G V+CK++ + L+ +S Y + + + R I+ R LS +I +W LS + P M Sbjct: 16 SLDNTSESGTTDPVGSNHLRT-IKLTLYTLIFLVSAAGNTLVCIVILKRKKMKTVT----NYFILNLAVADLALTCICIPFDIPVQEMGYIWPYGAVMCKVLYPLQTLTLFASVYTLTAVSLTRYWAIVHPLRKQLSVSKAKTLVIAIWVLSLLPVAPYMN 171
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO36377 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIX0]) HSP 1 Score: 60.4622 bits (145), Expect = 4.242e-10 Identity = 57/202 (28.22%), Postives = 95/202 (47.03%), Query Frame = 1 Query: 52 FDLHSKIKVTILLTF-FIVSVVGN--IVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGG---EVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRR--LSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGF 633 F +I +TI + F+V++VGN +V ++ R T+ N LI ++ +ADL +T + +T W+GG + LCK + S S + + I +DR II + L+ K+V ++ +W+ + F+ P + KV L K Y C + +S R Y V I +++PLA+IL Y F Sbjct: 19 FPADIQIGLTIFASLIFVVALVGNSIVVYIVCSCNHMRNTT------NILIANMAVADLWITFDIPYVIKWFYITDTWFGGGFGDFLCKFCHSAQAGSVACSVFTLVCISLDRSFAIIFPMKVILTRKIVKFMILGIWAATIAFTTPIFLITKVHL---KNGVYVCNELWEESGQSERHYIAVYTITTYIIPLALILIMYIF 211
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO41654 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3S0]) HSP 1 Score: 56.6102 bits (135), Expect = 4.520e-9 Identity = 54/219 (24.66%), Postives = 99/219 (45.21%), Query Frame = 1 Query: 103 VSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFL-LTETIWNMTTQWYGG---EVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRS--RRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLS 741 VS +GN + + + RR+ + F++LI+++ +ADL TI + + + + +W+ G E CK + FG N+S +S + +A I +DR I R LS + V + T+W ++ + +V+ GP + Y ++ ++ V +L + PL +G IMI L Q + G S + + + S K L+ Sbjct: 1 VSAIGNAMVIRHAVARRKLR----RSFDRLIINMAVADLLDTIFGVPYNISYFYIGLRWFPGTLGEFTCKFLNFGTNISITASVFTLAAIAVDRYFAIAHCAKRPLSLRSVRYIIATIWVIACMVFSSDYYRFRVIDGP-NGDVYCLQDANAWGKKAVQIDYIVKFVLNYAFPL-FAMGILYSIMIRYLWQTRGPGYASDSIERRVHEQRKRSVKKLLA 213
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: GNRHR (gonadotropin-releasing hormone II receptor-like [Source:NCBI gene;Acc:101167607]) HSP 1 Score: 96.2857 bits (238), Expect = 2.488e-21 Identity = 85/352 (24.15%), Postives = 154/352 (43.75%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI-----IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETR------VYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F +K++V I S N+ L ++ S LI++L +ADL VT + + + +WN+T QW G+ C+L+ F + + S ++ I +DR I I R+ ++++ LI W++S I S+PQ+ L + + +EF QC SFV R ++ F C+ FLLPL +++ CY I I K+ + ++N P+ E + + + +A+ ++L +S I+++++ TPY++ LG++ D + L+H F +LN+ +P+IYG F Sbjct: 52 LPTFSTAAKVRVIITFILCGFSAFFNLAVLWAAQSDGKRKSH----VKVLIINLTVADLLVTFIVMPLDAVWNITVQWLAGDFACRLLMFLKLQAMYSCAFVTVVISLDRQSAILNPLAINKARMRNRVM---LIAAWAMSVILSVPQIFLFHNVTIIYPEEFTQCAT--RGSFVSHRHETAYNLFTFACL---FLLPLVIMITCYTRIFCEISKRLK-----------------------------------RDNL------PSSELHLRCSKNNIPKARMRTLKMSIVIVLSFIICWTPYYL------LGLWYWFSPDDLEGKVSHSLTHILFIFGLLNACLDPVIYGLF 344
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: gnrh-r3 (gonadotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100125529]) HSP 1 Score: 95.5153 bits (236), Expect = 2.587e-21 Identity = 87/349 (24.93%), Postives = 156/349 (44.70%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVET------RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDE-----LSHWFFWLSILNSAFNPIIYGYF 1050 +P F +K++V I T VS V N++ L K ++ S LI++L +ADL VT + + + WN+T QW G++ C+L+ F + ++ S ++ I +DR I+ +S+ + I L W+ S I S+PQM + + + F QC SFV+ ++ FVC+ FLLPL +++ CY I++ I + + M+S + SH+ + +A+ ++L +S I+ +++ TPY++ LG++ + K++E L+H F + N+ +PI YG F Sbjct: 32 LPTFSTAAKVRVIITFTLCAVSAVCNLLVLWAAGKGGKRKSH----VRILIMNLTVADLLVTFIVMPVDAAWNITVQWQAGDLACRLLMFMKLVAMYSCAFVTVVISLDRQSAILNPLGISEAKRKSKIMLTVAWTTSVILSLPQMFIFHNVTITVPENFTQC--TTHGSFVQRWQETLYNMFTFVCL---FLLPLVIMIFCYTRILVEISSRIAR----NNMVSRDIHLRRSHNN-------------------------------------IPKARMRTLKMSIVIVTSFIICWTPYYL------LGLWYWLFPEKMEETVSHSLTHMLFIFGLFNACLDPITYGLF 324
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: gnrh-r1 (gonadotropin-releasing hormone receptor 1 [Source:NCBI gene;Acc:100125422]) HSP 1 Score: 93.2041 bits (230), Expect = 1.639e-20 Identity = 88/349 (25.21%), Postives = 150/349 (42.98%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKL--NKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F +K++V I VS + N L + +R++ LI++L ADL VT + + + WN+T QW G+ C+ + F + + S ++ I +DR I+R +S + L W++S + S+PQM + N + P F QC R + + ET ++ F C+ FLLPL++++ CY I I I KQ T K +S+ E K N + +A+ ++L +S I++ ++ TPY++ LG++ D + L+H F + N+ +PIIYG F Sbjct: 44 LPTFSTAAKVRVIITFILCGVSTLCNSAVLWAAIGHKRKSH-----VRVLIINLTAADLLVTFIVMPVDAAWNITVQWLAGDAACRFLMFLKLQAMYSCAFVTVVISLDRQSAILRPLSISAAPRRNRSMLTVAWTMSAVLSVPQMFIFHNVTITHP--ANFTQCTTRGSFVTHWQETAYNMFTFTCL---FLLPLSIMIICYTRIFIQISKQM---------------------TKKNVSSDEPHLRCSKNN--------------------IPKARMRTLKMSVVIVVGFIVCWTPYYL------LGLWYWFFPDDLEGKVSHSLTHILFIFGLFNTCLDPIIYGLF 335
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: gnrh-r1 (gonadotropin-releasing hormone receptor 1 [Source:NCBI gene;Acc:100125422]) HSP 1 Score: 93.2041 bits (230), Expect = 1.639e-20 Identity = 88/349 (25.21%), Postives = 150/349 (42.98%), Query Frame = 1 Query: 43 MPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSD--KMVVICLITVWSLSTIFSIPQMKL--NKVLLGPWKKEFYQC--RNIEMKSFVET--RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVF-----DTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 +P F +K++V I VS + N L + +R++ LI++L ADL VT + + + WN+T QW G+ C+ + F + + S ++ I +DR I+R +S + L W++S + S+PQM + N + P F QC R + + ET ++ F C+ FLLPL++++ CY I I I KQ T K +S+ E K N + +A+ ++L +S I++ ++ TPY++ LG++ D + L+H F + N+ +PIIYG F Sbjct: 44 LPTFSTAAKVRVIITFILCGVSTLCNSAVLWAAIGHKRKSH-----VRVLIINLTAADLLVTFIVMPVDAAWNITVQWLAGDAACRFLMFLKLQAMYSCAFVTVVISLDRQSAILRPLSISAAPRRNRSMLTVAWTMSAVLSVPQMFIFHNVTITHP--ANFTQCTTRGSFVTHWQETAYNMFTFTCL---FLLPLSIMIICYTRIFIQISKQM---------------------TKKNVSSDEPHLRCSKNN--------------------IPKARMRTLKMSVVIVVGFIVCWTPYYL------LGLWYWFFPDDLEGKVSHSLTHILFIFGLFNTCLDPIIYGLF 335
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Match: v1ar1 (arg8-vasotocin receptor-like [Source:NCBI gene;Acc:101155395]) HSP 1 Score: 91.6633 bits (226), Expect = 7.983e-20 Identity = 66/222 (29.73%), Postives = 116/222 (52.25%), Query Frame = 1 Query: 1 ENLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQ---MKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI 648 + L KN+S DP + +KI++T+L F+ +VVGN+ L+ + + RR+ S+ + + HL +ADL V +L + W +T ++YG + LC+++K + L +STY++ + +DR I +++ + + I + + W+ S + S PQ L++V G Y C M+ + R Y FLLP+A+++ CYGFI TI Sbjct: 22 QQLGGVKKNHS-DPFGRNEEVAKIEITVLSLAFVAAVVGNVSVLLAMHRTRRKLSR----MHLFMKHLSLADLVVAFFQVLPQLCWEITFRFYGPDFLCRIVKHLQVLGMFASTYMMVMMTLDRYIAICHPLKTLQQPTQRAYIMIGSTWACSLVLSTPQYFIFSLSEVRPG---SAVYDCWGHFMEPW-GLRAYITWITAGIFLLPVAILVFCYGFICRTI 234
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000002693.1 (SMESG000002693.1) HSP 1 Score: 805.053 bits (2078), Expect = 0.000e+0 Identity = 403/403 (100.00%), Postives = 403/403 (100.00%), Query Frame = 1 Query: 19 MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLVLKHPLKVRRPTQRVSL 1227 MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMISSSIIITYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLVLKHPLKVRRPTQRVSL Sbjct: 1 MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKKEFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLSFMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMISSSIIITYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYFNNLWFLPPRIRKYQKPKIIFQITWKTKCNKFKKQYNPNISLLVLKHPLKVRRPTQRVSL 403
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000074847.1 (SMESG000074847.1) HSP 1 Score: 129.413 bits (324), Expect = 1.484e-33 Identity = 97/321 (30.22%), Postives = 164/321 (51.09%), Query Frame = 1 Query: 22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI------IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI---LKQYQMIGKLSFMLSPLLMQHHSHSTNK-------TLSTSEKAGLTEKENQFYQYLEPNKEFLFQSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFL 933 N + +P+F+ ++ K L F +S++GN T+ F LK ++++ S++ ++I+ L AD+ V + F+LT+ IWN+ W GG LCKL+K G+ S STY+++ + +DR I + S + K+++ICL W S + +IPQ+ L GPWK FYQC + + ++ VYP V +L L+P+ +++ CY I+ TI K+Y+ ++ + H TN+ S S T N+ + ++ L K+ +SRAK K+ +S+ II +L PYW+ Y L Sbjct: 6 NNLTLPKIPSFNGYNLFKSVFFLVVFFISILGNTHTIFFTLKLQKRSKLSYRSLYRMIMQLAFADILVCLFFVLTQAIWNIFVSWRGGSFLCKLMKMGQAFSIYLSTYIMSLVSLDRAIAICKPIHHLHSWNRNIKIIIICL---WIYSFLLAIPQVLLFDAYRGPWKTVTFYQCTTSDNLNILQMYVYPLVYCVLILLIPIGILVTCYTVIIHTINVRSKEYEEHNSVTILFHHPKSDDCEHLTNQFPFYDDAKHSGSNNDNETIVINRISENSNNFQKLLSHKKQQLMSRAKIKTYRMSAIIISCFLLCWLPYWVYYVL 323
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000074847.1 (SMESG000074847.1) HSP 1 Score: 116.701 bits (291), Expect = 1.490e-29 Identity = 75/244 (30.74%), Postives = 131/244 (53.69%), Query Frame = 1 Query: 22 KNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVI---IRSRRLSDKMVVICLITVWSLSTIFSIPQMKLNKVLLGPWKK-EFYQCRNIEMKSFVETRVYPFVCIILAFLLPLAVILGCYGFIMITI---LKQYQMIGKLSFMLSPLLMQHHSHSTNK 732 N + +P+F+ ++ K L F +S++GN T+ F LK ++++ S++ ++I+ L AD+ V + F+LT+ IWN+ W GG LCKL+K G+ S STY+++ + +DR I I ++ + I +I +W S + +IPQ+ L GPWK FYQC + + ++ VYP V +L L+P+ +++ CY I+ TI K+Y+ ++ + H TN+ Sbjct: 6 NNLTLPKIPSFNGYNLFKSVFFLVVFFISILGNTHTIFFTLKLQKRSKLSYRSLYRMIMQLAFADILVCLFFVLTQAIWNIFVSWRGGSFLCKLMKMGQAFSIYLSTYIMSLVSLDRAIAICKPIHHLHSWNRNIKIIIICLWIYSFLLAIPQVLLFDAYRGPWKTVTFYQCTTSDNLNILQMYVYPLVYCVLILLIPIGILVTCYTVIIHTINVRSKEYEEHNSVTILFHHPKSDDCEHLTNQ 249
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000049782.1 (SMESG000049782.1) HSP 1 Score: 100.138 bits (248), Expect = 3.591e-23 Identity = 105/366 (28.69%), Postives = 170/366 (46.45%), Query Frame = 1 Query: 19 MKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIR--SRRLSDKMVVICLITVWSLSTIFSIPQMKL--NKVLLGPWKKEFYQCRNIEMKSFVET---RVYPFVCIILAFLLPLAVILGCYGFIMITILKQYQMIGKLS-------FMLSPLLMQHHSHSTNKTLSTSEKAGLTEKENQ----FYQYLEPNKEFLF----QSKRAFLSRAKFKSLMXXXXXXXTYLTSRTPYWMVYFLQHLGVFDTIVNSKLDELSHWFFWLSILNSAFNPIIYGYF 1050 ++NY+ + + K+K +LLT F++S+ N+ L F + RR S N LI+HLC AD+ IL + E +W +T QW LCK KF + S ST +I + IDR VI+ +R K + I + ++ S + +I Q+ + P+ F QC +I + V+ +V ++ + + LPL +I+ CY I+ T LK KL+ F P ++ ++ LS + KEN F + P F +SK RAK KS+ ++ SI++T++ TPY++VYF++ I + + F+ LN+ NPII G F Sbjct: 9 LRNYTIE----LGWYHKMKFCVLLTMFVMSLGTNVFVLAFAYRIRRIKST----LNILIIHLCYADILAGILCMFGECLWILTIQWNASSWLCKFYKFSISFSISLSTGIICVMSIDRTLVIMYPLNRLKMAKRIKILIGIMYMGSCLINISQVTMFDTAQAPAPYPLPFIQCVHISLFMKVQQWRLKVVFWMHYVFNYALPLIIIIVCYSLIL-TRLKDASRWNKLNNFHQRYCFSKPPSVISMSQECSSSILSCKQ-----SKENNSIILFSKIHSPTSNHSFSHNLKSKNTLFRRAKKKSIKLTFSIVLTFVVCWTPYYIVYFIRSYS--GPIHRFDPRDPGIYSFFFGHLNAIINPIICGVF 358
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000046683.1 (SMESG000046683.1) HSP 1 Score: 83.9593 bits (206), Expect = 7.482e-18 Identity = 58/164 (35.37%), Postives = 86/164 (52.44%), Query Frame = 1 Query: 19 MKNYS-----TDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRRRQTSQSFKGFNKLILHLCIADLSVTILFLLTETIWNMTTQWYGGEVLCKLIKFGRNLSFLSSTYLIATIGIDRVQVIIRSRRLSDKM------VVICLITVWSLSTIFSIPQMK 477 MKN + T PMP + ++ K T F +SVVGN T+ F+LK R + S +K +L L +AD+SV I F+L I N W G +CK +K + S STY++ I IDRV V IR L + V+IC ++W ++ + S+PQ++ Sbjct: 1 MKNVTSVQNVTIPMPQLNGYNLFKAIFFYTSFSISVVGNFNTIFFILKIYRHSKVSCIHLHKTLLQLALADISVAIFFILNLAILNTLGSWQAGRWVCKFVKVWQAFSIYLSTYVVVFISIDRV-VAIRFPLLHSRCWKRYFNVIIC--SIWLITFVLSLPQIQ 161 The following BLAST results are available for this feature:
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Gonadotropin-releasing hormone receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030787 ID=SMED30030787|Name=Gonadotropin-releasing hormone receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1242bpback to top protein sequence of SMED30030787-orf-1 >SMED30030787-orf-1 ID=SMED30030787-orf-1|Name=SMED30030787-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=410bp ENLKVTMKNYSTDPMPNFDLHSKIKVTILLTFFIVSVVGNIVTLIFLLKRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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