Protein kinase C and casein kinase substrate in neurons protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30030763 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Human
Match: PACSIN1 (protein kinase C and casein kinase substrate in neurons 1 [Source:HGNC Symbol;Acc:HGNC:8570]) HSP 1 Score: 281.952 bits (720), Expect = 2.034e-88 Identity = 158/496 (31.85%), Postives = 266/496 (53.63%), Query Frame = 3 Query: 114 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 MS+S++ E + ++FW++ Y +T++R+++ ++LC D+ N +Q+R +IEK+Y L W+ +W +E G +YGS ++ W EA+++S+LH++++ L+++ V+NWQ++ +HK + KE K E F AQKPWAKK+K++ KK YH CK + + N+ + S++ EQ KK+++K+ K ++D +K + Y+ L ++ +Y+E M +VF + Q E++R+ F K + I++ LNL+EN + +Y+ E I+ D D+ + G P + PQFEE+ +L H+ +KK+ GV LT + +++ ++GD G S++S G +T + E+ +P S ET +P D V+VRALYDY G E+DEL+ K GD KL +EDEQGWC+G+ D G++GLYPANY E + Sbjct: 1 MSSSYD-EASLAPEETTDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMG--GFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTTKKEKQPKKAEGVALTNAT-GAVESTSQAGDRG------SVSSYDRGQPYATEWSDDESGNPFGGS------------------------------------------ETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 444
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Human
Match: PACSIN1 (protein kinase C and casein kinase substrate in neurons 1 [Source:HGNC Symbol;Acc:HGNC:8570]) HSP 1 Score: 281.952 bits (720), Expect = 2.034e-88 Identity = 158/496 (31.85%), Postives = 266/496 (53.63%), Query Frame = 3 Query: 114 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 MS+S++ E + ++FW++ Y +T++R+++ ++LC D+ N +Q+R +IEK+Y L W+ +W +E G +YGS ++ W EA+++S+LH++++ L+++ V+NWQ++ +HK + KE K E F AQKPWAKK+K++ KK YH CK + + N+ + S++ EQ KK+++K+ K ++D +K + Y+ L ++ +Y+E M +VF + Q E++R+ F K + I++ LNL+EN + +Y+ E I+ D D+ + G P + PQFEE+ +L H+ +KK+ GV LT + +++ ++GD G S++S G +T + E+ +P S ET +P D V+VRALYDY G E+DEL+ K GD KL +EDEQGWC+G+ D G++GLYPANY E + Sbjct: 1 MSSSYD-EASLAPEETTDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMG--GFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTTKKEKQPKKAEGVALTNAT-GAVESTSQAGDRG------SVSSYDRGQPYATEWSDDESGNPFGGS------------------------------------------ETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 444
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Human
Match: PACSIN1 (protein kinase C and casein kinase substrate in neurons 1 [Source:HGNC Symbol;Acc:HGNC:8570]) HSP 1 Score: 281.952 bits (720), Expect = 2.034e-88 Identity = 158/496 (31.85%), Postives = 266/496 (53.63%), Query Frame = 3 Query: 114 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 MS+S++ E + ++FW++ Y +T++R+++ ++LC D+ N +Q+R +IEK+Y L W+ +W +E G +YGS ++ W EA+++S+LH++++ L+++ V+NWQ++ +HK + KE K E F AQKPWAKK+K++ KK YH CK + + N+ + S++ EQ KK+++K+ K ++D +K + Y+ L ++ +Y+E M +VF + Q E++R+ F K + I++ LNL+EN + +Y+ E I+ D D+ + G P + PQFEE+ +L H+ +KK+ GV LT + +++ ++GD G S++S G +T + E+ +P S ET +P D V+VRALYDY G E+DEL+ K GD KL +EDEQGWC+G+ D G++GLYPANY E + Sbjct: 1 MSSSYD-EASLAPEETTDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMG--GFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTTKKEKQPKKAEGVALTNAT-GAVESTSQAGDRG------SVSSYDRGQPYATEWSDDESGNPFGGS------------------------------------------ETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 444
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Human
Match: PACSIN2 (protein kinase C and casein kinase substrate in neurons 2 [Source:HGNC Symbol;Acc:HGNC:8571]) HSP 1 Score: 280.796 bits (717), Expect = 5.585e-88 Identity = 165/487 (33.88%), Postives = 267/487 (54.83%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC+D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ F EAE +S+LH +++ L++D ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS IY + E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q S+ S + S K+ + P+ ++ E+++P S++ D + P + ++ TE V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQ-SLPSKPSSVSSYEKTQSYPTDWSDD-------ESNNPFSST-------DANGDSNPF------------------DDDATSGTE--------------VRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 444
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Human
Match: PACSIN2 (protein kinase C and casein kinase substrate in neurons 2 [Source:HGNC Symbol;Acc:HGNC:8571]) HSP 1 Score: 280.796 bits (717), Expect = 5.585e-88 Identity = 165/487 (33.88%), Postives = 267/487 (54.83%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC+D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ F EAE +S+LH +++ L++D ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS IY + E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q S+ S + S K+ + P+ ++ E+++P S++ D + P + ++ TE V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKATDGVTLTGINQTGDQ-SLPSKPSSVSSYEKTQSYPTDWSDD-------ESNNPFSST-------DANGDSNPF------------------DDDATSGTE--------------VRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 444
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Celegans
Match: sdpn-1 (SynDaPiN (Synaptic dynamin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q6AHQ8]) HSP 1 Score: 197.593 bits (501), Expect = 1.992e-56 Identity = 138/488 (28.28%), Postives = 236/488 (48.36%), Query Frame = 3 Query: 171 FWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQK-ILNLSENKNLTDIYQNFENTIQTLDPDS---DIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLT-AVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSS-----PLSTSALRRLEP-DLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSD-EDYVQVR---ALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 FW++ Y ++R ++ + D C M ++R EIE YS L + + KW ++++ + GS K W EA +S +H ++ LIDDI + +++ H S + KE + +E F+ AQKPW K + KM + +Y+ C+ +S V +N DTS+S + K E+ K +++ ++ K Y +L LN N Y+E M VF Q E +R F + + Q+ N+ N ++ ++Q E +I++ D ++ D+AQWS + G D P F EY+ E+ +I+ + + + GV LT +N + S S ++ + + G + S +TS+ ST+ + +P + PP P S+ +S TETP +S + D E++ + LYDY E DE+ L++G++ L + D GWC G+ G VGL+PA+Y + Sbjct: 10 FWEVGSYKHNVKRFKDGVEQLDDYCKMSRERAEIEAKYSKMLSQHAEKWRAHVDRTVSAGSVKTVWNELIGEATALSRVHNSLKDCLIDDIVNETTTYRKNSLHTSVF--KGPKEIREIEDHFEKAQKPWKKLVDKMEDKRGKYYNVCRQEKSALVNLQNCQTDTSVSPDAATKFRERHEKLKEEVQRTKVDYQKTLTNLNEYKNVYMEAMAHVFKMCQEKEMDRSQFLIGIVQKTQRHYANIIRNSQMSGLHQQLEQSIRSADSEAVKRDLAQWSSVNGVDAFSEWPSFVEYSPEIRNIAARGGSTKDAGGVILTRQINRSEDIPSTHSNTLPSVAVNTASSHEDVGKSSPKSSSESDTSTFDSRKHNSTANKYKNQPQNTTQIQPP--PVGWHPSDGP--------DSPPLSTETP--DSAKYGDFEEFTTSKPAVVLYDYAPAEGDEIALRKGEMIEVLTEPDSLGWCTGRVSGNVGLFPASYVQ 483
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Celegans
Match: sdpn-1 (SynDaPiN (Synaptic dynamin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q6AHQ8]) HSP 1 Score: 197.593 bits (501), Expect = 1.992e-56 Identity = 138/488 (28.28%), Postives = 236/488 (48.36%), Query Frame = 3 Query: 171 FWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQK-ILNLSENKNLTDIYQNFENTIQTLDPDS---DIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLT-AVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSS-----PLSTSALRRLEP-DLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSD-EDYVQVR---ALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 FW++ Y ++R ++ + D C M ++R EIE YS L + + KW ++++ + GS K W EA +S +H ++ LIDDI + +++ H S + KE + +E F+ AQKPW K + KM + +Y+ C+ +S V +N DTS+S + K E+ K +++ ++ K Y +L LN N Y+E M VF Q E +R F + + Q+ N+ N ++ ++Q E +I++ D ++ D+AQWS + G D P F EY+ E+ +I+ + + + GV LT +N + S S ++ + + G + S +TS+ ST+ + +P + PP P S+ +S TETP +S + D E++ + LYDY E DE+ L++G++ L + D GWC G+ G VGL+PA+Y + Sbjct: 10 FWEVGSYKHNVKRFKDGVEQLDDYCKMSRERAEIEAKYSKMLSQHAEKWRAHVDRTVSAGSVKTVWNELIGEATALSRVHNSLKDCLIDDIVNETTTYRKNSLHTSVF--KGPKEIREIEDHFEKAQKPWKKLVDKMEDKRGKYYNVCRQEKSALVNLQNCQTDTSVSPDAATKFRERHEKLKEEVQRTKVDYQKTLTNLNEYKNVYMEAMAHVFKMCQEKEMDRSQFLIGIVQKTQRHYANIIRNSQMSGLHQQLEQSIRSADSEAVKRDLAQWSSVNGVDAFSEWPSFVEYSPEIRNIAARGGSTKDAGGVILTRQINRSEDIPSTHSNTLPSVAVNTASSHEDVGKSSPKSSSESDTSTFDSRKHNSTANKYKNQPQNTTQIQPP--PVGWHPSDGP--------DSPPLSTETP--DSAKYGDFEEFTTSKPAVVLYDYAPAEGDEIALRKGEMIEVLTEPDSLGWCTGRVSGNVGLFPASYVQ 483
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Celegans
Match: sdpn-1 (SynDaPiN (Synaptic dynamin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q6AHQ8]) HSP 1 Score: 197.208 bits (500), Expect = 3.667e-56 Identity = 138/488 (28.28%), Postives = 236/488 (48.36%), Query Frame = 3 Query: 171 FWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQK-ILNLSENKNLTDIYQNFENTIQTLDPDS---DIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLT-AVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSS-----PLSTSALRRLEP-DLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSD-EDYVQVR---ALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 FW++ Y ++R ++ + D C M ++R EIE YS L + + KW ++++ + GS K W EA +S +H ++ LIDDI + +++ H S + KE + +E F+ AQKPW K + KM + +Y+ C+ +S V +N DTS+S + K E+ K +++ ++ K Y +L LN N Y+E M VF Q E +R F + + Q+ N+ N ++ ++Q E +I++ D ++ D+AQWS + G D P F EY+ E+ +I+ + + + GV LT +N + S S ++ + + G + S +TS+ ST+ + +P + PP P S+ +S TETP +S + D E++ + LYDY E DE+ L++G++ L + D GWC G+ G VGL+PA+Y + Sbjct: 16 FWEVGSYKHNVKRFKDGVEQLDDYCKMSRERAEIEAKYSKMLSQHAEKWRAHVDRTVSAGSVKTVWNELIGEATALSRVHNSLKDCLIDDIVNETTTYRKNSLHTSVF--KGPKEIREIEDHFEKAQKPWKKLVDKMEDKRGKYYNVCRQEKSALVNLQNCQTDTSVSPDAATKFRERHEKLKEEVQRTKVDYQKTLTNLNEYKNVYMEAMAHVFKMCQEKEMDRSQFLIGIVQKTQRHYANIIRNSQMSGLHQQLEQSIRSADSEAVKRDLAQWSSVNGVDAFSEWPSFVEYSPEIRNIAARGGSTKDAGGVILTRQINRSEDIPSTHSNTLPSVAVNTASSHEDVGKSSPKSSSESDTSTFDSRKHNSTANKYKNQPQNTTQIQPP--PVGWHPSDGP--------DSPPLSTETP--DSAKYGDFEEFTTSKPAVVLYDYAPAEGDEIALRKGEMIEVLTEPDSLGWCTGRVSGNVGLFPASYVQ 489
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Celegans
Match: abi-1 (ABl Interactor homolog [Source:UniProtKB/TrEMBL;Acc:Q10929]) HSP 1 Score: 53.9138 bits (128), Expect = 1.891e-7 Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 3 Query: 1431 QVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 +VR LYDY +EDELTL++ + Y L+ D+ W +G DG GL+P NY V Sbjct: 416 KVRVLYDYDAAKEDELTLRENAIVYVLKKNDDD-WYEGVLDGVTGLFPGNYVVPV 469
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Celegans
Match: abi-1 (ABl Interactor homolog [Source:UniProtKB/TrEMBL;Acc:Q10929]) HSP 1 Score: 53.9138 bits (128), Expect = 1.891e-7 Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 3 Query: 1431 QVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 +VR LYDY +EDELTL++ + Y L+ D+ W +G DG GL+P NY V Sbjct: 416 KVRVLYDYDAAKEDELTLRENAIVYVLKKNDDD-WYEGVLDGVTGLFPGNYVVPV 469
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Fly
Match: Synd (gene:FBgn0053094 transcript:FBtr0334725) HSP 1 Score: 319.701 bits (818), Expect = 1.186e-102 Identity = 177/485 (36.49%), Postives = 272/485 (56.08%), Query Frame = 3 Query: 156 AGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMAS-PSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISS---NKSVTRNDHRQNS---ISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 AG ++FW+ Y +T +R+E+ KLC D+ +IQ+R +IEK Y+ SL WS KW +E G EYG+T+ W G E+E ISD+H ++ L +D+ + ++ WQ+E++H + + +KE K LE F AQKPWAK L K+ + K +YH CK RS Q +NA D+S+S +Q+KKM ++++K++ +K + Y+ ++ E+ + Y+E+MT VF K Q EK R+ FFK + + L+L++ ++L IY+ F +TI D D+ WS +G + + P F EYT+E I+K + +T +N + +S+ K+ ++ S + AS S T S ++TS + + + ++ N SVT + + ++ E V + E V V+ALYDY G E DELT KQGD+F KLEDEDEQGWCKG+ +GRVGLYPANY E Sbjct: 12 AGSDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLM---QIKERKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEFRDIAKGNKSKEALPAAPITLINQRPVAEDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATAASAASNRNSSVTNGNGKVDANPFDEEEEWDESDNVLVDNGEPGVPVKALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMNGRVGLYPANYVE 493
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Fly
Match: Synd (gene:FBgn0053094 transcript:FBtr0334724) HSP 1 Score: 319.701 bits (818), Expect = 1.186e-102 Identity = 177/485 (36.49%), Postives = 272/485 (56.08%), Query Frame = 3 Query: 156 AGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMAS-PSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISS---NKSVTRNDHRQNS---ISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 AG ++FW+ Y +T +R+E+ KLC D+ +IQ+R +IEK Y+ SL WS KW +E G EYG+T+ W G E+E ISD+H ++ L +D+ + ++ WQ+E++H + + +KE K LE F AQKPWAK L K+ + K +YH CK RS Q +NA D+S+S +Q+KKM ++++K++ +K + Y+ ++ E+ + Y+E+MT VF K Q EK R+ FFK + + L+L++ ++L IY+ F +TI D D+ WS +G + + P F EYT+E I+K + +T +N + +S+ K+ ++ S + AS S T S ++TS + + + ++ N SVT + + ++ E V + E V V+ALYDY G E DELT KQGD+F KLEDEDEQGWCKG+ +GRVGLYPANY E Sbjct: 12 AGSDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLM---QIKERKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEFRDIAKGNKSKEALPAAPITLINQRPVAEDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATAASAASNRNSSVTNGNGKVDANPFDEEEEWDESDNVLVDNGEPGVPVKALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMNGRVGLYPANYVE 493
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Fly
Match: Synd (gene:FBgn0053094 transcript:FBtr0083966) HSP 1 Score: 316.62 bits (810), Expect = 1.750e-101 Identity = 175/484 (36.16%), Postives = 266/484 (54.96%), Query Frame = 3 Query: 156 AGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISS---NKSVTRNDHRQNS---ISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 AG ++FW+ Y +T +R+E+ KLC D+ +IQ+R +IEK Y+ SL WS KW +E G EYG+T+ W G E+E ISD+H ++ L +D+ + ++ WQ+E++H + + +KE K LE F AQKPWAK L K+ + K +YH CK RS Q +NA D+S+S +Q+KKM ++++K++ +K + Y+ ++ E+ + Y+E+MT VF K Q EK R+ FFK + + L+L++ ++L IY+ F +TI D D+ WS +G + + P F EYT+E I+K + +T +N + + S + AS S T S ++TS + + + ++ N SVT + + ++ E V + E V V+ALYDY G E DELT KQGD+F KLEDEDEQGWCKG+ +GRVGLYPANY E Sbjct: 12 AGSDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLM---QIKERKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEFRDIAKGNKSKEALPAAPITLINQRPVAEDVHEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATAASAASNRNSSVTNGNGKVDANPFDEEEEWDESDNVLVDNGEPGVPVKALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMNGRVGLYPANYVE 492
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Fly
Match: Abp1 (gene:FBgn0036372 transcript:FBtr0075819) HSP 1 Score: 56.225 bits (134), Expect = 5.164e-8 Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 3 Query: 1431 QVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKG-KKDGRVGLYPANYAEIV 1595 + RALYDY +E E+T GD+ ++ DE GW +G DG GL+PANY EI+ Sbjct: 476 RARALYDYQAADETEITFDPGDVITHIDQIDE-GWWQGLGPDGTYGLFPANYVEII 530
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Fly
Match: Abi (gene:FBgn0020510 transcript:FBtr0307076) HSP 1 Score: 51.6026 bits (122), Expect = 1.260e-6 Identity = 22/53 (41.51%), Postives = 34/53 (64.15%), Query Frame = 3 Query: 1431 QVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 +V A+YDY ++DEL+ ++ + Y L+ D+ GW +G DG GL+P NY E Sbjct: 418 KVVAIYDYYADKDDELSFQESSVLYVLKKNDD-GWWEGVMDGVTGLFPGNYVE 469
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Zebrafish
Match: pacsin1b (protein kinase C and casein kinase substrate in neurons 1b [Source:NCBI gene;Acc:619246]) HSP 1 Score: 306.22 bits (783), Expect = 5.279e-98 Identity = 171/482 (35.48%), Postives = 266/482 (55.19%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSF--NMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+E+ ++LC D+ + IQ+R +IEK+YS L WS +W +E G +YG+ ++ WL EAE++S+LH++++ L+++ V+NWQ++ +HK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ + S++ +Q KK++EK+ K + D +K K Y+ SL+ELN +Y+E M VF++ Q E++R+ F + + ++ LNL+E+++ +Y+ E TI + D+ +S ++G + PQFEE+ +L H+ISKK+ N GVTLT V + G +P TG S S+ N + S+ S +D PP + +N +P D V+VRALYDY G E+DELT K GD KLEDEDEQGWCKG+ D G++GLYPANY E V Sbjct: 15 TDSFWEVGNYKRTVKRIEDGHRLCNDMMSCIQERAKIEKAYSQQLTDWSKRWRQLVERGPQYGTLERAWLAVMTEAEKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQMMG--GFKETKEADEGFRKAQKPWAKKLKELETAKKTYHMACKEEKIASAREANSKGEASVTTDQQKKLQEKVDKCKNDVQKAKEKYEKSLDELNKCTPQYMENMEVVFDQCQQFEEKRLNFLREVLLDTKRHLNLTESQSYATVYRELERTIVSASAQEDLKWFSSVHGPGMHMNWPQFEEFNPDLSHAISKKEKVKRNHDGVTLTQV-----------------THGAEHGTPQTGDRGSVSSYEKNQQYSAEWS-----------DDEQPPTAAQSASETNGG---------------------NPFEEDSKGVRVRALYDYEGQEQDELTFKAGDELTKLEDEDEQGWCKGRLDSGQLGLYPANYVEPV 445
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Zebrafish
Match: pacsin1b (protein kinase C and casein kinase substrate in neurons 1b [Source:NCBI gene;Acc:619246]) HSP 1 Score: 306.22 bits (783), Expect = 5.279e-98 Identity = 171/482 (35.48%), Postives = 266/482 (55.19%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSF--NMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+E+ ++LC D+ + IQ+R +IEK+YS L WS +W +E G +YG+ ++ WL EAE++S+LH++++ L+++ V+NWQ++ +HK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ + S++ +Q KK++EK+ K + D +K K Y+ SL+ELN +Y+E M VF++ Q E++R+ F + + ++ LNL+E+++ +Y+ E TI + D+ +S ++G + PQFEE+ +L H+ISKK+ N GVTLT V + G +P TG S S+ N + S+ S +D PP + +N +P D V+VRALYDY G E+DELT K GD KLEDEDEQGWCKG+ D G++GLYPANY E V Sbjct: 15 TDSFWEVGNYKRTVKRIEDGHRLCNDMMSCIQERAKIEKAYSQQLTDWSKRWRQLVERGPQYGTLERAWLAVMTEAEKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQMMG--GFKETKEADEGFRKAQKPWAKKLKELETAKKTYHMACKEEKIASAREANSKGEASVTTDQQKKLQEKVDKCKNDVQKAKEKYEKSLDELNKCTPQYMENMEVVFDQCQQFEEKRLNFLREVLLDTKRHLNLTESQSYATVYRELERTIVSASAQEDLKWFSSVHGPGMHMNWPQFEEFNPDLSHAISKKEKVKRNHDGVTLTQV-----------------THGAEHGTPQTGDRGSVSSYEKNQQYSAEWS-----------DDEQPPTAAQSASETNGG---------------------NPFEEDSKGVRVRALYDYEGQEQDELTFKAGDELTKLEDEDEQGWCKGRLDSGQLGLYPANYVEPV 445
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Zebrafish
Match: pacsin1b (protein kinase C and casein kinase substrate in neurons 1b [Source:NCBI gene;Acc:619246]) HSP 1 Score: 306.22 bits (783), Expect = 5.279e-98 Identity = 171/482 (35.48%), Postives = 266/482 (55.19%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSF--NMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+E+ ++LC D+ + IQ+R +IEK+YS L WS +W +E G +YG+ ++ WL EAE++S+LH++++ L+++ V+NWQ++ +HK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ + S++ +Q KK++EK+ K + D +K K Y+ SL+ELN +Y+E M VF++ Q E++R+ F + + ++ LNL+E+++ +Y+ E TI + D+ +S ++G + PQFEE+ +L H+ISKK+ N GVTLT V + G +P TG S S+ N + S+ S +D PP + +N +P D V+VRALYDY G E+DELT K GD KLEDEDEQGWCKG+ D G++GLYPANY E V Sbjct: 15 TDSFWEVGNYKRTVKRIEDGHRLCNDMMSCIQERAKIEKAYSQQLTDWSKRWRQLVERGPQYGTLERAWLAVMTEAEKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQMMG--GFKETKEADEGFRKAQKPWAKKLKELETAKKTYHMACKEEKIASAREANSKGEASVTTDQQKKLQEKVDKCKNDVQKAKEKYEKSLDELNKCTPQYMENMEVVFDQCQQFEEKRLNFLREVLLDTKRHLNLTESQSYATVYRELERTIVSASAQEDLKWFSSVHGPGMHMNWPQFEEFNPDLSHAISKKEKVKRNHDGVTLTQV-----------------THGAEHGTPQTGDRGSVSSYEKNQQYSAEWS-----------DDEQPPTAAQSASETNGG---------------------NPFEEDSKGVRVRALYDYEGQEQDELTFKAGDELTKLEDEDEQGWCKGRLDSGQLGLYPANYVEPV 445
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Zebrafish
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2596]) HSP 1 Score: 284.263 bits (726), Expect = 6.243e-89 Identity = 162/479 (33.82%), Postives = 269/479 (56.16%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETE--TPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAE 1589 ++FW++ Y ++++R+++ N+LC D+ + + +R IEKSYS+ L W+ +W +E G +YG+ ++ W EAE++SDLH +++ L+ + ++NWQ++ +HK + KE K E F AQKPWAKKLK+M KK YH CK ++ + ++ D S + Q KK++EK+ K +++ +K K Y+ SL +L+ +Y+E M +VF + Q E +R++FFK + +++ L+LS N T +Y ++TIQ DP D+ + +G + PQFEE++ +L+ ++S+++ GVTLTA++ N Q+S S S + +P + + +S ++ E + +A P + + ++ N S+ + P +E P S E V VRA+YDY G E+DEL+ K GD KL +EDEQGWCKG+ +G VGLYPANY E Sbjct: 14 DSFWEVGNYKRSVKRVDDGNRLCNDLMSCLHERARIEKSYSTQLTDWAKRWRQTIEKGPQYGTVERAWCALMTEAEKVSDLHMEVKAALMAEDFEKIKNWQKDAYHKQMIG--GFKETKEAEDGFRKAQKPWAKKLKEMETMKKAYHTACKEEKTATSRENSSKLDNSNPEAQ-KKLQEKVEKCQQEVQKTKERYEKSLEDLDKVTPQYMENMEQVFEQWQQFEGKRLSFFKEVLLEVKQHLDLSSNHKYTTVYHTLQDTIQGADPQEDLKWFRSNHGPGMTMNWPQFEEWSMDLNRTLSRRETKRRPAEGVTLTAISHNPEQSSRVSSVPAVSSSEAACLNPFDDDDDDEDEDEEPVVTHTHSSPVKHEEAVAQTAAVEKAPAPAAITAADDDDDEESGNPFSSSSANGNPFEEEP--STEMCVPVRAVYDYEGQEQDELSFKAGDELVKLSEEDEQGWCKGRLSNGTVGLYPANYVE 487
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Zebrafish
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2596]) HSP 1 Score: 283.878 bits (725), Expect = 9.825e-89 Identity = 164/480 (34.17%), Postives = 268/480 (55.83%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQN---SISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAE 1589 ++FW++ Y ++++R+++ N+LC D+ + + +R IEKSYS+ L W+ +W +E G +YG+ ++ W EAE++SDLH +++ L+ + ++NWQ++ +HK + KE K E F AQKPWAKKLK+M KK YH CK ++ + ++ D S + Q KK++EK+ K +++ +K K Y+ SL +L+ +Y+E M +VF + Q E +R++FFK + +++ L+LS N T +Y ++TIQ DP D+ + +G + PQFEE++ +L+ ++S+++ GVTLTA++ N Q+S S S + +P + + +S ++ E + SA K + + +D S S+ P +E P S E V VRA+YDY G E+DEL+ K GD KL +EDEQGWCKG+ +G VGLYPANY E Sbjct: 14 DSFWEVGNYKRSVKRVDDGNRLCNDLMSCLHERARIEKSYSTQLTDWAKRWRQTIEKGPQYGTVERAWCALMTEAEKVSDLHMEVKAALMAEDFEKIKNWQKDAYHKQMIG--GFKETKEAEDGFRKAQKPWAKKLKEMETMKKAYHTACKEEKTATSRENSSKLDNSNPEAQ-KKLQEKVEKCQQEVQKTKERYEKSLEDLDKVTPQYMENMEQVFEQWQQFEGKRLSFFKEVLLEVKQHLDLSSNHKYTTVYHTLQDTIQGADPQEDLKWFRSNHGPGMTMNWPQFEEWSMDLNRTLSRRETKRRPAEGVTLTAISHNPEQSSRVSSVPAVSSSEAACLNPFDDDDDDEDEDEEPVVTHTHSSPVKHEEAVAQTSAAVEKAPAPAAITAADDDDDEESGNPFSSSSANGNPFEEEP--STEMCVPVRAVYDYEGQEQDELSFKAGDELVKLSEEDEQGWCKGRLSNGTVGLYPANYVE 488
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Xenopus
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:NCBI gene;Acc:496460]) HSP 1 Score: 294.278 bits (752), Expect = 9.056e-93 Identity = 170/492 (34.55%), Postives = 280/492 (56.91%), Query Frame = 3 Query: 138 GETSNSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLE-PDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 G +S GV ++FW++ Y +T++R+++ ++LC+D+ N I +R +IEK+Y+ L +W+ +W +E G +YG+ ++ W EAE++S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK YH CK + + N+ D +++ EQLKK+++K+ KS++DS+K K Y+ +L +L+G +Y+E M +VF + Q E +R+ FF+ + ++K L+LS + +IY+ E I++ D D+ + G + PQFEE++ +L+ ++ GVTLT ++ QA +++ + S+ + PS A+ P + E + ++ + ++ + D P + SN T ND +S P E + E V+VRALYDY G E DEL+ K G+ K+EDEDEQGWCKG+ D G+VGLYPANY E V Sbjct: 3 GTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCIHERAKIEKAYAQQLTEWAKRWKQLVERGPQYGTVEKAWHNLMTEAEKVSELHLEVKNALMNEDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAYHAACKEEKLATSRETNSKADPAMNPEQLKKLQDKVEKSKQDSQKTKEKYEKALKDLDGTTPQYMENMEQVFEQCQQFEDKRLRFFREVLLEVEKHLDLSNVDSYANIYRELEYAIKSADATEDLKWFRNNNGPGMSMNWPQFEEWSADLNRTLSRREKKKPTDGVTLTGISQAGEQAPVQNKHSSHLSV---QSVPS----ANNPFEDEEDTGSINETENKKTKNVGSYDKTYPAE-WSDDESNNPFTANDANGDS------NPFDEDAPGATE--VRVRALYDYEGQELDELSFKAGEELTKIEDEDEQGWCKGRLDGGQVGLYPANYVESV 476
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Xenopus
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:NCBI gene;Acc:496460]) HSP 1 Score: 293.893 bits (751), Expect = 1.127e-92 Identity = 167/491 (34.01%), Postives = 270/491 (54.99%), Query Frame = 3 Query: 138 GETSNSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 G +S GV ++FW++ Y +T++R+++ ++LC+D+ N I +R +IEK+Y+ L +W+ +W +E G +YG+ ++ W EAE++S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK YH CK + + N+ D +++ EQLKK+++K+ KS++DS+K K Y+ +L +L+G +Y+E M +VF + Q E +R+ FF+ + ++K L+LS + +IY+ E I++ D D+ + G + PQFEE++ +L+ ++ GVTLT ++ QA +++ + + + P + +F S D P + SN T ND +S P E + E V+VRALYDY G E DEL+ K G+ K+EDEDEQGWCKG+ D G+VGLYPANY E V Sbjct: 3 GTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCIHERAKIEKAYAQQLTEWAKRWKQLVERGPQYGTVEKAWHNLMTEAEKVSELHLEVKNALMNEDFEKIKNWQKEAFHKQMM--GGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAYHAACKEEKLATSRETNSKADPAMNPEQLKKLQDKVEKSKQDSQKTKEKYEKALKDLDGTTPQYMENMEQVFEQCQQFEDKRLRFFREVLLEVEKHLDLSNVDSYANIYRELEYAIKSADATEDLKWFRNNNGPGMSMNWPQFEEWSADLNRTLSRREKKKPTDGVTLTGISQAGEQAPVQNKHSRYVPLAVASVPPPRFVSHHSCTFIHSVGS--------------YDKTYPAE-WSDDESNNPFTANDANGDS------NPFDEDAPGATE--VRVRALYDYEGQELDELSFKAGEELTKIEDEDEQGWCKGRLDGGQVGLYPANYVESV 468
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Xenopus
Match: sult6b1.4 (sulfotransferase family 6B member 1 gene 4 [Source:Xenbase;Acc:XB-GENE-5735978]) HSP 1 Score: 280.796 bits (717), Expect = 6.922e-88 Identity = 164/477 (34.38%), Postives = 255/477 (53.46%), Query Frame = 3 Query: 171 FWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 FW+ Y +T++R+E+ N+LC D+ + ++R +IEKSY+ L WS KW + LE G +YG+ ++ W F AE++S++H ++R +L D+ VR+WQ+E FHK + +E+K E F AQKPW KKLK + KK YH K R+ V+ ++ D+++SQEQL+K+ +++ K ++++K K +Y+ +L ELN RY+E+M + F Q E++R+ FFK M K L+LS + + ++ +IQT D D+ W +G + PQFEE++ E +ISKK+ + N VTLT + + +R T + + G S T+ + T +P S + ED +P KS+ N + + V+VRALYDY G E DEL+ G+ K+ EDEQGWC+G+ GR+GLYPANY E V Sbjct: 15 FWEAGNYRQTVKRIEDGNRLCNDLVSCFRERAKIEKSYAQQLSDWSNKWRTSLEKGPQYGTLEKSWQAFLTAAEKLSEIHTELRNQLWDEDSGKVRDWQKEAFHKQMIG--GFRESKEAEESFSKAQKPWVKKLKDVEVAKKRYHVARKDERAAQVREDHSKADSTVSQEQLRKLRDRVEKCNQEADKTKGVYEKALEELNRYNPRYMEDMEQAFESCQEAEQKRLCFFKEMLLDFHKHLDLSSKDSFHVLNKDLHQSIQTADDQQDLKWWRNTHGPSMAMNWPQFEEWSPETQRTISKKERSNKNVEEVTLTGI-LPARDGVSAGTPTQQLNRGFSY------TDEDQDFYATLTDTPHSDTGKDDASEWSEDDSP----------KKSMDSNGREVSQVEG-----------------VRVRALYDYAGQEADELSFTAGEELMKIGSEDEQGWCRGRLLSGRIGLYPANYVEGV 455
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Xenopus
Match: PACSIN1 (protein kinase C and casein kinase substrate in neurons 1 [Source:NCBI gene;Acc:100494558]) HSP 1 Score: 279.256 bits (713), Expect = 1.631e-87 Identity = 163/481 (33.89%), Postives = 259/481 (53.85%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLY-GADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW+L Y +T++R+++ ++LC D+ + +QDR +IEK+YS L W+ +W +E G +YG+ ++ W EAE I +LH++++ L+ + VRNWQ+E +HK + KE++ E F AQKPWAKK+K++ KK YH CK + + + D S++ +QL+K+++K+ K ++D +K + Y+ L+++ +Y+E M VF + Q ME++R+ F K I+ LNLSE+ + +YQ E TIQ+ D D+ +W ++Y G + PQFEE+ ++ H+I++K+ G LT V + + +S + GD G S T+A T ++ D E P + SN P +E V+VRALYDY G E+DEL+ K G+ KLEDEDEQGWC+G+ D GR GLYPANY E + Sbjct: 9 TDSFWELGHYKRTVKRIDDGHRLCNDLMSCLQDRAKIEKAYSQQLTDWAKRWRQLIEKGPQYGTLERAWGALLTEAERIGELHQEVKNHLVSEDMEKVRNWQKESYHKQMMG--GFKESREAEEGFRKAQKPWAKKMKEVEAAKKTYHMACKEEKLASSREASGKADASVTADQLRKLQDKVEKCKQDVQKAQERYEKILDDIQKFTPQYMESMDLVFEQCQQMEEKRLVFLKEALLDIKHHLNLSESSSYAAVYQELEQTIQSSDVQEDL-RWFRVYHGPGMHMNWPQFEEWNPDVTHTIARKE-KTKKTEGAVLTNVAVTTENSS-QGGDRGS-------VSSYDRTQAYTADWS-----------------DDEGGNSSSYP--TADSNGGA---------------NPFEEEGALR----VRVRALYDYEGQEQDELSFKAGEELTKLEDEDEQGWCRGQLDSGRQGLYPANYVESI 439
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Xenopus
Match: sult6b1.4 (sulfotransferase family 6B member 1 gene 4 [Source:Xenbase;Acc:XB-GENE-5735978]) HSP 1 Score: 275.018 bits (702), Expect = 7.070e-86 Identity = 162/481 (33.68%), Postives = 252/481 (52.39%), Query Frame = 3 Query: 171 FWDLK----QYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 FW+++ Y +T++R+E+ N+LC D+ + ++R +IEKSY+ L WS KW + LE G +YG+ ++ W F AE++S++H ++R +L D+ VR+WQ+E FHK + +E+K E F AQKPW KKLK + KK YH K R+ V+ ++ D+++SQEQL+K+ +++ K ++++K K +Y+ +L ELN RY+E+M + F Q E++R+ FFK M K L+LS + + ++ +IQT D D+ W +G + PQFEE++ E +ISKK+ + N VTLT + RD G A TP+ + + + D + + P +S+ SN S + V+VRALYDY G E DEL+ G+ K+ EDEQGWC+G+ GR+GLYPANY E V Sbjct: 15 FWEVRGSAGNYRQTVKRIEDGNRLCNDLVSCFRERAKIEKSYAQQLSDWSNKWRTSLEKGPQYGTLEKSWQAFLTAAEKLSEIHTELRNQLWDEDSGKVRDWQKEAFHKQMIG--GFRESKEAEESFSKAQKPWVKKLKDVEVAKKRYHVARKDERAAQVREDHSKADSTVSQEQLRKLRDRVEKCNQEADKTKGVYEKALEELNRYNPRYMEDMEQAFESCQEAEQKRLCFFKEMLLDFHKHLDLSSKDSFHVLNKDLHQSIQTADDQQDLKWWRNTHGPSMAMNWPQFEEWSPETQRTISKKERSNKNVEEVTLTGIL------------PARD-----------GVSAGTPTQQLNRGTG---------KDDASEWSEDDSPKKSMDSN-----------------------GREVSQVEGVRVRALYDYAGQEADELSFTAGEELMKIGSEDEQGWCRGRLLSGRIGLYPANYVEGV 438
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Mouse
Match: Pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:MGI Symbol;Acc:MGI:1345153]) HSP 1 Score: 293.123 bits (749), Expect = 2.632e-92 Identity = 165/490 (33.67%), Postives = 278/490 (56.73%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEAS--TPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETET-PIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ EAE +S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K+ Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS + IY+ E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q +G++ G +++ PS +++ S+N + S++ E + + ++ ++ S +++ +S A ++ P E E V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVDGVTLTGINQTGDQ-------SGQNKPGSNLSVPSNPAQSTQLQSSYNPFEDEDDTGSSISEKEDIKAKNVSSYEKTQTYPTDWSDDESNNPFSSTDANGDSNPFDEDTTSGTE--VRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Mouse
Match: Pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:MGI Symbol;Acc:MGI:1345153]) HSP 1 Score: 293.123 bits (749), Expect = 2.632e-92 Identity = 165/490 (33.67%), Postives = 278/490 (56.73%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEAS--TPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETET-PIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ EAE +S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K+ Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS + IY+ E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q +G++ G +++ PS +++ S+N + S++ E + + ++ ++ S +++ +S A ++ P E E V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVDGVTLTGINQTGDQ-------SGQNKPGSNLSVPSNPAQSTQLQSSYNPFEDEDDTGSSISEKEDIKAKNVSSYEKTQTYPTDWSDDESNNPFSSTDANGDSNPFDEDTTSGTE--VRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Mouse
Match: Pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:MGI Symbol;Acc:MGI:1345153]) HSP 1 Score: 293.123 bits (749), Expect = 2.632e-92 Identity = 165/490 (33.67%), Postives = 278/490 (56.73%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEAS--TPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETET-PIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ EAE +S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K+ Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS + IY+ E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q +G++ G +++ PS +++ S+N + S++ E + + ++ ++ S +++ +S A ++ P E E V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVDGVTLTGINQTGDQ-------SGQNKPGSNLSVPSNPAQSTQLQSSYNPFEDEDDTGSSISEKEDIKAKNVSSYEKTQTYPTDWSDDESNNPFSSTDANGDSNPFDEDTTSGTE--VRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Mouse
Match: Pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:MGI Symbol;Acc:MGI:1345153]) HSP 1 Score: 293.123 bits (749), Expect = 2.632e-92 Identity = 165/490 (33.67%), Postives = 278/490 (56.73%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEAS--TPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETET-PIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ EAE +S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K+ Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS + IY+ E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q +G++ G +++ PS +++ S+N + S++ E + + ++ ++ S +++ +S A ++ P E E V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVDGVTLTGINQTGDQ-------SGQNKPGSNLSVPSNPAQSTQLQSSYNPFEDEDDTGSSISEKEDIKAKNVSSYEKTQTYPTDWSDDESNNPFSSTDANGDSNPFDEDTTSGTE--VRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Mouse
Match: Pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:MGI Symbol;Acc:MGI:1345153]) HSP 1 Score: 293.123 bits (749), Expect = 2.632e-92 Identity = 165/490 (33.67%), Postives = 278/490 (56.73%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEAS--TPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETET-PIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ EAE +S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K+ Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS + IY+ E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q +G++ G +++ PS +++ S+N + S++ E + + ++ ++ S +++ +S A ++ P E E V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVDGVTLTGINQTGDQ-------SGQNKPGSNLSVPSNPAQSTQLQSSYNPFEDEDDTGSSISEKEDIKAKNVSSYEKTQTYPTDWSDDESNNPFSSTDANGDSNPFDEDTTSGTE--VRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. UniProt/SwissProt
Match: sp|Q07840|EM13_ECHMU (Antigen EM13 OS=Echinococcus multilocularis OX=6211 GN=EM13 PE=2 SV=1) HSP 1 Score: 329.717 bits (844), Expect = 1.888e-106 Identity = 181/451 (40.13%), Postives = 275/451 (60.98%), Query Frame = 3 Query: 249 MIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTND---SGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDL-EDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSD-----EDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYP 1574 MIQ+R +IEK+Y+S+L K++ + +L +G+EYG+ G +EAE+ ++LH ++ LI+ +Q ++NWQRE+FHKS++ ++KE K+ +SEF+ AQK W K K +N+CKKEY CK VRS VQ +NA N+ + EQL+K+E+KLRK + EK + Y+ +L+ L+ RY+E+MT+VFNK+QA E+ER+ +FK ++Q++L++S NL+ I+ T+ +D D+D+ +WS YG D + P F+EY+ E+ ++ KK + D GVTLT++ +I S D G P GT T S + ++SP+ T+A D + A P S++ + +IS E + ++++P + D V +RALYDY+GVE DEL+ GDLF KLEDEDEQGWCKG+KDGRVGLYP Sbjct: 1 MIQERADIEKAYASNLRKFAARLEMFLRTGVEYGTATNILSGLAKEAEDNAELHSNIAAGLINPVQLGIKNWQRENFHKSSIS-TSIKEVKNFDSEFENAQKTWYKHYKNVNRCKKEYFHACKTVRSLQVQVQNAKNEPFGTPEQLRKIEDKLRKGIMEEEKTRKAYEEALSSLSDVTPRYIEDMTQVFNKAQAFERERIIYFKEQALQMQEVLDISAKPNLSQIFVGLRETVAKVDADADLKKWSLAYGVDMAPNFPVFQEYSPEMSALGKKGRSALADGSSGGVTLTSLK------TITSPDRG---------GPIPGT---TDSGSNISTSPVHTTAYGSNSYDHGSEGATPSDYTSSVNGAAA---------AISKEKQR-VEDTPPYPDFVDDGRPGVPIRALYDYVGVEADELSFNSGDLFEKLEDEDEQGWCKGRKDGRVGLYP 422
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. UniProt/SwissProt
Match: sp|Q07839|EG13_ECHGR (Antigen EG13 OS=Echinococcus granulosus OX=6210 GN=EG13 PE=2 SV=1) HSP 1 Score: 317.39 bits (812), Expect = 7.438e-102 Identity = 175/457 (38.29%), Postives = 265/457 (57.99%), Query Frame = 3 Query: 249 MIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQ-------LKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTND---SGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSD-----EDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYP 1574 MIQ+R +IEK+Y+S+L K++ + +L +G+EYG+ G +EAE+ ++LH ++ LI+ +Q ++NWQRE+FHKS++ ++KE K+ +SEF+ AQK W K K +N+CKKEY CK VRS VQ +NA N+ + EQ L+KME+KLRK + EK + Y+ +++ L+ RY+E+MT+VFNK+QA E+ER+ +FK ++Q +L++S NL+ I+ T+ +D D+D+ +WS YG D + P F+EY+ E+ ++ KK + D GVTLT++ K+ SP G P ++ S +STS P + SV + ++S E + ++++P + D V +RALYDY+GVE DEL+ GDLF KLEDEDEQGWCKG+KDGRVGLYP Sbjct: 1 MIQERADIEKAYASNLRKFAARLEMFLRTGVEYGTATNILSGLAKEAEDNAELHSNIAAGLINPVQLGIKNWQRENFHKSSIS-TSIKEVKNFDSEFENAQKTWYKHYKNVNRCKKEYFHACKTVRSLQVQVQNAKNEPFGTPEQQAQRGKELRKMEDKLRKGIMEEEKTRKAYEEAISSLSDVTPRYIEDMTQVFNKAQAFERERIVYFKEQALQMQAVLDISAKPNLSQIFVELRETVAKVDADADLKKWSLAYGVDMAPNFPVFQEYSPEMSALGKKGRSALADGSSGGVTLTSL--------------------KTFTSPDRG--GPIPG-TTDSGSNISTS-----------------PVHTTDYTSSV---NGAAAAVSKEKQR-VEDTPPYPDFVDDGRPGVPIRALYDYVGVEADELSFNSGDLFEKLEDEDEQGWCKGRKDGRVGLYP 412
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. UniProt/SwissProt
Match: sp|Q4V920|PACN1_DANRE (Protein kinase C and casein kinase substrate in neurons protein 1 OS=Danio rerio OX=7955 GN=pacsin1b PE=1 SV=1) HSP 1 Score: 306.22 bits (783), Expect = 3.985e-97 Identity = 171/482 (35.48%), Postives = 266/482 (55.19%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSF--NMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+E+ ++LC D+ + IQ+R +IEK+YS L WS +W +E G +YG+ ++ WL EAE++S+LH++++ L+++ V+NWQ++ +HK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ + S++ +Q KK++EK+ K + D +K K Y+ SL+ELN +Y+E M VF++ Q E++R+ F + + ++ LNL+E+++ +Y+ E TI + D+ +S ++G + PQFEE+ +L H+ISKK+ N GVTLT V + G +P TG S S+ N + S+ S +D PP + +N +P D V+VRALYDY G E+DELT K GD KLEDEDEQGWCKG+ D G++GLYPANY E V Sbjct: 15 TDSFWEVGNYKRTVKRIEDGHRLCNDMMSCIQERAKIEKAYSQQLTDWSKRWRQLVERGPQYGTLERAWLAVMTEAEKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQMMG--GFKETKEADEGFRKAQKPWAKKLKELETAKKTYHMACKEEKIASAREANSKGEASVTTDQQKKLQEKVDKCKNDVQKAKEKYEKSLDELNKCTPQYMENMEVVFDQCQQFEEKRLNFLREVLLDTKRHLNLTESQSYATVYRELERTIVSASAQEDLKWFSSVHGPGMHMNWPQFEEFNPDLSHAISKKEKVKRNHDGVTLTQV-----------------THGAEHGTPQTGDRGSVSSYEKNQQYSAEWS-----------DDEQPPTAAQSASETNGG---------------------NPFEEDSKGVRVRALYDYEGQEQDELTFKAGDELTKLEDEDEQGWCKGRLDSGQLGLYPANYVEPV 445
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. UniProt/SwissProt
Match: sp|Q9WVE8|PACN2_MOUSE (Protein kinase C and casein kinase substrate in neurons protein 2 OS=Mus musculus OX=10090 GN=Pacsin2 PE=1 SV=1) HSP 1 Score: 293.123 bits (749), Expect = 1.841e-91 Identity = 165/490 (33.67%), Postives = 278/490 (56.73%), Query Frame = 3 Query: 150 NSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEAS--TPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETET-PIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 +S GV ++FW++ Y +T++R+++ ++LC D+ N + +R IEK+Y+ L +W+ +W +E G +YG+ ++ W+ EAE +S+LH +++ L+++ ++NWQ+E FHK + KE K E F AQKPWAKKLK++ KK +H CK + + N+ D S++ EQLKK+++K+ K ++D K K+ Y+ SL EL+ +Y+E M +VF + Q E++R+ FF+ + +QK L+LS + IY+ E +I+ D D+ + +G + PQFEE++ +L+ ++ GVTLT +N Q +G++ G +++ PS +++ S+N + S++ E + + ++ ++ S +++ +S A ++ P E E V+VRALYDY G E DEL+ K GD K+EDEDEQGWCKG+ D G+VGLYPANY E + Sbjct: 7 DSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMG--GFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFEEWSADLNRTLSRREKKKAVDGVTLTGINQTGDQ-------SGQNKPGSNLSVPSNPAQSTQLQSSYNPFEDEDDTGSSISEKEDIKAKNVSSYEKTQTYPTDWSDDESNNPFSSTDANGDSNPFDEDTTSGTE--VRVRALYDYEGQEHDELSFKAGDELTKIEDEDEQGWCKGRLDSGQVGLYPANYVEAI 485
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. UniProt/SwissProt
Match: sp|Q9DDA9|PACN2_XENLA (Protein kinase C and casein kinase substrate in neurons protein 2 OS=Xenopus laevis OX=8355 GN=pacsin2 PE=2 SV=1) HSP 1 Score: 291.582 bits (745), Expect = 4.322e-91 Identity = 165/496 (33.27%), Postives = 275/496 (55.44%), Query Frame = 3 Query: 138 GETSNSAGV----NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSM--GKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEP---DLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 G +S GV ++FW++ Y +T++R+++ ++LC D+ N I +R IEK Y+ L +W+ +W +E G +YG+ ++ W EAE++S+LH +++ L+++ ++NWQ+E FHK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ D +++ EQLKK+++K+ KS++DS+K K Y+ SL +L+G +Y+E M +VF + Q E +R++FF+ + ++K L+LS ++ IY+ E I++ D D+ + +G + PQFE+++ +L+ ++ GVTLT ++ + Q+SI++ + S+ +S +P E + E + + + P ++S P P + N P E + + E V+VRALYDY G E DEL+ K G+ K+EDEDEQGWCKG+ + G+VGLYPANY E V Sbjct: 3 GTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCNDLMNCIHERARIEKVYAQQLTEWAKRWKQLVERGPQYGTVEKAWHNLMTEAEKVSELHLEVKNALMNEDFEKIKNWQKEAFHKQMMG--GFKETKEADDGFRKAQKPWAKKLKEVEAAKKSYHAACKEEKLATSRETNSKADPAMNPEQLKKLQDKVEKSKQDSQKTKEKYEKSLKDLDGTTPQYMENMEQVFEQCQQFEDKRLSFFREVLLEVEKHLDLSNVESYASIYRELEYAIKSADAMEDLKWFRNNHGPGMSMNWPQFEDWSADLNRTLSRREKKKPTDGVTLTGISQSGEQSSIQNQHSSHLSVQSAQSTNNPFEDEEETVSINETENKKIENVGSYEKTHPAEWSDDESNNPFNPSDTNGDN------------------NPFDEDALTTLE--VRVRALYDYDGQELDELSFKAGEELTKIEDEDEQGWCKGRLEGGQVGLYPANYVESV 476
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. TrEMBL
Match: G4V9S3 (Putative membrane traffic protein OS=Schistosoma mansoni OX=6183 GN=Smp_140490 PE=4 SV=1) HSP 1 Score: 401.364 bits (1030), Expect = 6.158e-131 Identity = 211/507 (41.62%), Postives = 311/507 (61.34%), Query Frame = 3 Query: 135 EGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSI-SKKKLNLTN-DSGVTLTAVNMNSRQASIRSGDT----------GRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDE----------DYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 E E NS+ ++FW+ ++Y +T++R++ A KLC ++C MIQ+R E+EK+YSS+L KWS++W S+L+SG+EYGS W G C+EAE +S+ H+++R LID+IQT+V+ WQ+EHFHKS+LPPQ LKE K E +F+IAQK W+K+LKK++ KKEY+Q CK RS VQ +NA +D S + EQLKK +EKL K+EKD + ++ Y +L +LN + +RYVEEMTKVFN++Q E+ER++FFK +F+ + LN+ + IY +I D ++D+ WS +G D PF +PQFEEY+ +L I SKK+ LT+ ++ VTLT + M S S + + S+ S + G N +T++P A + KP + + + + + P++ +E + V+VRALYDY+G + DE++ GD F KLE+ D+QGWCKG+KDGRVGLYPANY E Sbjct: 6 EYEDQNSSNASSFWECREYHRTVKRVDAAYKLCNELCLMIQERAELEKAYSSNLKKWSSRWLSFLDSGLEYGSGSSPWKGLCKEAEAVSNAHQNVRNILIDEIQTEVKQWQKEHFHKSSLPPQTLKETKQFEQDFEIAQKQWSKRLKKVHTTKKEYYQACKTERSLQVQVRNAKSDPSGTAEQLKKTQEKLAKAEKDVHRTRDAYKIALADLNTESSRYVEEMTKVFNRTQDFERERLSFFKEIFNSLHSALNVCAKVDYDSIYNELAESISQCDVEADLNLWSSNHGVDMPFVSPQFEEYSPDLAYITSKKRATLTDPNAPVTLTNITMISHPFDNESDEITSNNSKSNNNHNKKLDNSIVSSANGR-------NHDTNNPFDDKA-----------STNTKPTNGVKAGEYAMSSSSAAAFAGGGDGSV---DPIYFEEINDATYDDGREGVKVRALYDYVGQDGDEISFLAGDTFEKLEEPDDQGWCKGRKDGRVGLYPANYVE 491
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. TrEMBL
Match: A0A504YA41 (Adaptor protein pacsin OS=Fasciola gigantica OX=46835 GN=FGIG_01093 PE=4 SV=1) HSP 1 Score: 394.43 bits (1012), Expect = 3.000e-128 Identity = 199/488 (40.78%), Postives = 305/488 (62.50%), Query Frame = 3 Query: 150 NSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQ------LKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTND--SGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 N ++FWD + + KT++R E ANKLC+++ MI +R E+E+ Y+++L +W+ +W S+L+SG YG+ W G C+EAE IS+ H+D+R L D+IQ +++WQ+EHFHK++LPPQ+LKE+K E +FD AQKPWAK++KK+NQCKK+Y+Q CKM RS VQ +NA ND + + EQ LKKM++K +KSEK+ E+ + Y ++L+ L+ D RY+EEMT VF+++Q E+ER+ FFK +F+ + + LN++ + IY++ E +I +D ++D+ WS +G D P PQFEEY+ EL +IS KK + ++ SGVTLT + + + + + ++ TP F+ + P + + +P ED P ++ + ++ D+ ++ + I VRALYDY G E+DE++ GD F KLE+ D+QGWCKG+KDGRVGLYPANYAE Sbjct: 10 NGLSASSFWDFRGHQKTVKRAEVANKLCSELSLMIHERAELERVYAANLKRWTARWLSFLDSGFVYGTGISPWKGLCQEAEAISNAHQDIRNVLTDEIQPGLKHWQKEHFHKTSLPPQSLKESKQFEQDFDQAQKPWAKRMKKVNQCKKDYYQACKMERSLQVQVQNAKNDPNGTPEQMEVDPKLKKMQDKWKKSEKEVERTRAAYTNALSGLDADNPRYLEEMTAVFSRTQDFERERLIFFKDLFANLHQALNVTTKADFNVIYRDLEESIAKMDIEADLNWWSANHGVDMPAVLPQFEEYSPELTAISSKKRSTVSETNSGVTLTGITPVISSPEVIPNRPSQAQIETNHNMNGLNSDIHTP-FDDGLTGPPTPTTPVGAQP--EDGGQVSAPVGDLTGHDEISDADYYASATYDDGRPGIP------------VRALYDYTGQEDDEISFVAGDRFEKLEEADDQGWCKGRKDGRVGLYPANYAE 482
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. TrEMBL
Match: A0A4E0RQB9 (Adaptor protein pacsin OS=Fasciola hepatica OX=6192 GN=D915_001138 PE=4 SV=1) HSP 1 Score: 392.504 bits (1007), Expect = 1.638e-127 Identity = 198/488 (40.57%), Postives = 306/488 (62.70%), Query Frame = 3 Query: 150 NSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQ------LKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTND--SGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 N ++FWD + + KT++R E ANKLC+++ MI +R E+E+ Y+++L +W+ +W S+L+SG YG++ W G C+EAE IS+ H+D+R L D+IQ +++WQ+EHFHK++LPPQ+LKE+K E +FD AQKPWAK++KK+NQCKK+Y+Q CKM RS VQ +NA ND + + EQ LKKM++K +KSEK+ E+ + Y ++L+ L+ D RY+EEMT VF+++Q E++R+ FFK +F+ + + LN++ + IY++ E +I +D ++D+ WS +G D P PQFEEY+ EL +IS KK + ++ SGVTLT + + + + + ++ TP F+ + P + + +P ED P ++ + ++ D+ ++ + I VRALYDY G E+DE++ GD F KLE+ D+QGWCKG+KDGRVGLYPANYAE Sbjct: 10 NGLSASSFWDFRGHQKTVKRAEVANKLCSELSLMIHERAELERVYAANLKRWTARWLSFLDSGFVYGTSISPWKGLCQEAEAISNAHQDIRNVLTDEIQPGLKHWQKEHFHKTSLPPQSLKESKQFEQDFDQAQKPWAKRMKKVNQCKKDYYQACKMERSLQVQVQNAKNDPNGTPEQMEVDPKLKKMQDKWKKSEKEVERTRAAYTNALSGLDADNPRYLEEMTAVFSRTQDFERDRLIFFKDLFANLHQALNVTTKADFNVIYRDLEESIAKMDIEADLNWWSVNHGVDMPAVLPQFEEYSPELTAISSKKRSTVSETNSGVTLTGITPVISSPEVIPNRPSQAQIETNHNMNGLNSDIHTP-FDDGLTGPPTPTTPVGAQP--EDGGQVSVPVGDMTGHDEISDADYYASATYDDGRPGIP------------VRALYDYTGQEDDEISFVAGDRFEKLEEADDQGWCKGRKDGRVGLYPANYAE 482
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. TrEMBL
Match: A0A430QRV4 (Protein kinase C and casein kinase substrate in neurons protein OS=Schistosoma bovis OX=6184 GN=DC041_0004309 PE=4 SV=1) HSP 1 Score: 390.578 bits (1002), Expect = 4.163e-126 Identity = 216/534 (40.45%), Postives = 316/534 (59.18%), Query Frame = 3 Query: 135 EGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILN-----------------------------------------LSENKNLTD-IYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSIS-KKKLNLTN-DSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTE----ASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEI 1592 E E NS+ ++FW+ ++Y +T++R++ A KLC ++C MIQ+R E+EK+YSS+L KWS++W S+L+SG+EYGS W G C+EAE +S+ H+++R LIDDIQT V+ WQ+EHFHKS+LPPQ LKE K E +F++AQK W+K+LKK++ KKEY+Q CK RS VQ +NA +D S + EQLKK +EKL K+EKD + ++ Y +L +LN + +RYVEEMTKVFN++Q E+ER++FFK +F+ + LN L EN D IY +I D ++D+ WS +G D PF +PQFEEY+ +L I+ KK+ LT+ DS VTLT + M S S + ++ + + + +E +S N +T++P +P +A ++SS + I + I ++ + V+VRALYDY+G + DE++ GD F KLE+ D+QGWCKG+KDGRVGLYPANY E+ Sbjct: 6 EYEDQNSSNASSFWECREYHRTVKRVDAAYKLCNELCLMIQERAELEKAYSSNLKKWSSRWLSFLDSGLEYGSGSSPWKGLCKEAEAVSNAHQNVRNILIDDIQTGVKQWQKEHFHKSSLPPQTLKETKQFEQDFELAQKQWSKRLKKVHTTKKEYYQACKTERSLQVQVRNAKSDPSGTAEQLKKTQEKLAKAEKDVYRTRDAYKMALADLNTESSRYVEEMTKVFNRTQDFERERLSFFKDIFNSLHGALNVCAKVNNNNNNNNNNNNNNNNNNNNSSSNNNNNNYRNDIFFLVENIFSYDSIYSELAESISQCDVEADLNLWSSNHGVDMPFVSPQFEEYSPDLAYITGKKRATLTDPDSPVTLTNITMISHPFDHESNEITSNNSRSNNNNHNKKSENTIVSSANGRNSDTNNPFDDKVSTNRKPTNGVNA----SVYAMSSGSAAAFAGDGDGGIDSMYTEEINDATYDDGREGVKVRALYDYVGQDGDEISFVAGDTFEKLEEPDDQGWCKGRKDGRVGLYPANYVEL 535
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. TrEMBL
Match: A0A564XWN1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS511 PE=4 SV=1) HSP 1 Score: 375.555 bits (963), Expect = 1.321e-121 Identity = 197/488 (40.37%), Postives = 301/488 (61.68%), Query Frame = 3 Query: 147 SNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTND--SGVTLTAVNMNS---RQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 +++A +FW+ QY++T++R++NANKLC+++ MIQ+R +IE++Y+++L K++++ ++L+SGIEYG+ G +EA + +DLH ++ T LI+ +QT ++NWQ+E+FHKS++ ++KE KS ++EF+ AQK W K K++N+CKKEY CK VRS VQ +NA N+ + EQL++ME+KL+K+ + EK + Y +++ LN RY+++MT+VFNK+QA EK+R+ +FK +Q++L++S NL I+ ++TI +D D+D+ +WS LYG D P + P F+EY+ EL ++ KK + D SGVTLT++ M S R + DT + S+ +T T P+ E + L PDL D P P +RALYDY+GVE DEL+ KQGDLF KLEDEDEQGWCKG+KDGRVGLYPANY +++ Sbjct: 10 ADNATTVSFWEPNQYIRTVKRVDNANKLCSELSIMIQERSDIERAYAANLQKFASRLETFLKSGIEYGTGSNLISGLAKEARDTADLHSNIATDLINPVQTGIKNWQKENFHKSSIS-SSIKEVKSFDAEFENAQKTWYKNYKQVNKCKKEYFHACKAVRSLQVQVQNAKNEPFGTPEQLRRMEDKLKKATTEEEKTRKAYLDAISALNDVTPRYMDDMTQVFNKAQAFEKKRIEYFKQQVLAMQEVLDVSSKSNLPKIFAEMKDTISKVDADADLKKWSLLYGVDMPTNFPAFQEYSPELCALGKKGKSAVADTNSGVTLTSMKMISSPERPTNAGVTDTALTAGYNSLNGGTTSTVVQQPTAITENVA---------LYPDLIDDGRPGVP-----------------------------------------IRALYDYVGVESDELSFKQGDLFEKLEDEDEQGWCKGRKDGRVGLYPANYVQVL 446
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Cavefish
Match: pacsin1b (protein kinase C and casein kinase substrate in neurons protein 1 [Source:NCBI gene;Acc:103037534]) HSP 1 Score: 294.278 bits (752), Expect = 1.733e-93 Identity = 166/482 (34.44%), Postives = 261/482 (54.15%), Query Frame = 3 Query: 159 GVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSD-EDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ ++LC D+ N I +R +IEK+Y+ L WS +W +E G +YG+ ++ W+ E E++S+LH++++ L+++ V+NWQ++ +HK + KE K E F AQKPWAKKLK++ KK YH CK + + N+ +T EQ KK++EK+ K + D +K K Y+ +L+EL +Y+E M VF + Q E++R++F + + +++ LNL+EN++ IY++ E TI + D+ +S +G + PQFEEY +L H+ISKK+ N GVTLT V +GD A+P TG S S++ + S +D Q + ET +P D V+VRALYDY G E+DEL+ + GD KLEDED+QGWCKG+ D G++GLYPANY E + Sbjct: 14 ATDSFWEVGNYKRTVKRIDDGHRLCNDLMNCIHERAKIEKAYAQQLTDWSKRWRQLVEKGPQYGTVERGWITVMTETEKVSELHQEVKNNLLNEDLEKVKNWQKDSYHKQIMG--GFKETKEAEEGFKKAQKPWAKKLKELETAKKAYHMACKEEKLASTREANSKGETPAPAEQQKKLQEKVEKCKNDVQKAKEKYEKALDELGKCTPQYMENMEGVFEQCQQFEEKRLSFVREVLLDVKRHLNLTENQSYATIYRDLERTITSASAQEDLKWFSNNHGPGMHMNWPQFEEYNPDLTHAISKKEKVKKNHDGVTLTHV--------TPAGD---------HATPPTGDRGSVSSYDK-------------------------------NQGYSAEWSDEDQPAAQQAAETNGGNNPFEEDVSKGVRVRALYDYEGQEQDELSFRAGDELTKLEDEDDQGWCKGRLDSGQLGLYPANYVEPI 445
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Cavefish
Match: pacsin1b (protein kinase C and casein kinase substrate in neurons protein 1 [Source:NCBI gene;Acc:103037534]) HSP 1 Score: 294.278 bits (752), Expect = 1.733e-93 Identity = 166/482 (34.44%), Postives = 261/482 (54.15%), Query Frame = 3 Query: 159 GVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSD-EDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ ++LC D+ N I +R +IEK+Y+ L WS +W +E G +YG+ ++ W+ E E++S+LH++++ L+++ V+NWQ++ +HK + KE K E F AQKPWAKKLK++ KK YH CK + + N+ +T EQ KK++EK+ K + D +K K Y+ +L+EL +Y+E M VF + Q E++R++F + + +++ LNL+EN++ IY++ E TI + D+ +S +G + PQFEEY +L H+ISKK+ N GVTLT V +GD A+P TG S S++ + S +D Q + ET +P D V+VRALYDY G E+DEL+ + GD KLEDED+QGWCKG+ D G++GLYPANY E + Sbjct: 14 ATDSFWEVGNYKRTVKRIDDGHRLCNDLMNCIHERAKIEKAYAQQLTDWSKRWRQLVEKGPQYGTVERGWITVMTETEKVSELHQEVKNNLLNEDLEKVKNWQKDSYHKQIMG--GFKETKEAEEGFKKAQKPWAKKLKELETAKKAYHMACKEEKLASTREANSKGETPAPAEQQKKLQEKVEKCKNDVQKAKEKYEKALDELGKCTPQYMENMEGVFEQCQQFEEKRLSFVREVLLDVKRHLNLTENQSYATIYRDLERTITSASAQEDLKWFSNNHGPGMHMNWPQFEEYNPDLTHAISKKEKVKKNHDGVTLTHV--------TPAGD---------HATPPTGDRGSVSSYDK-------------------------------NQGYSAEWSDEDQPAAQQAAETNGGNNPFEEDVSKGVRVRALYDYEGQEQDELSFRAGDELTKLEDEDDQGWCKGRLDSGQLGLYPANYVEPI 445
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Cavefish
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons protein 2 [Source:NCBI gene;Acc:103038884]) HSP 1 Score: 294.278 bits (752), Expect = 8.200e-93 Identity = 165/493 (33.47%), Postives = 275/493 (55.78%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPI--------------KESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ N+LC D+ N I +R IEK+Y+ L +W+ +W +E G +YG+ ++ W EAE++SDLH +++ L+ + V+NWQ++ +HK + KE K + F AQKPWAKKLK+++ KK YH CK + + + +++ + E KK+++K+ K ++D +K K Y+ SL EL+ +Y+E M +VF + Q E +R++FFK + +++ L+LS N +YQN E++IQ D + D+ + +G P + PQFEE++ +L+ ++S+++ +D VTLT +N ++GD + S+A PS+ F+ + P ++ + P+ + +K+ + + Q+ ET P SPV S V VRALYDY G E+DEL+ K GD F K+ +ED+QGWCKG+ KDG VGLYPANY E + Sbjct: 15 DSFWEIGNYKRTVKRVDDGNRLCNDLMNCIHERARIEKAYAQQLTEWAKRWRQLIEKGPQYGTVERAWCALMTEAEKVSDLHMEVKAALMAEDFEKVKNWQKDAYHKQMI--GGFKETKEADDGFRKAQKPWAKKLKEVDTTKKVYHTACKEEKLATSRENTSKLESNTNPEAQKKLQDKVEKCQQDVQKTKERYEKSLEELDKVTPQYMENMEQVFEQCQQFEDKRLSFFKELLLEVKQHLDLSTNHKFQTVYQNLEDSIQAADAEEDLKWFRSNHGPGMPMNWPQFEEWSIDLNRTLSRREKKKPSDE-VTLTGIN--------QTGDRPAKTNNNSLAVPSSTEPVGLNPFDDDDEEEEEEEV-----PAVQPKSSPVNVKKEEVISKTASSVEKTQDWSDEETGNPFGADSNGNGNPFEDEPNSPVIS----VPVRALYDYEGQEQDELSFKAGDEFTKIGEEDDQGWCKGRLKDGTVGLYPANYVEDI 487
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Cavefish
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons protein 2 [Source:NCBI gene;Acc:103038884]) HSP 1 Score: 283.878 bits (725), Expect = 1.106e-88 Identity = 165/509 (32.42%), Postives = 275/509 (54.03%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFE----------------EYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPI--------------KESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ N+LC D+ N I +R IEK+Y+ L +W+ +W +E G +YG+ ++ W EAE++SDLH +++ L+ + V+NWQ++ +HK + KE K + F AQKPWAKKLK+++ KK YH CK + + + +++ + E KK+++K+ K ++D +K K Y+ SL EL+ +Y+E M +VF + Q E +R++FFK + +++ L+LS N +YQN E++IQ D + D+ + +G P + PQFE E++ +L+ ++S+++ +D VTLT +N ++GD + S+A PS+ F+ + P ++ + P+ + +K+ + + Q+ ET P SPV S V VRALYDY G E+DEL+ K GD F K+ +ED+QGWCKG+ KDG VGLYPANY E + Sbjct: 15 DSFWEIGNYKRTVKRVDDGNRLCNDLMNCIHERARIEKAYAQQLTEWAKRWRQLIEKGPQYGTVERAWCALMTEAEKVSDLHMEVKAALMAEDFEKVKNWQKDAYHKQMI--GGFKETKEADDGFRKAQKPWAKKLKEVDTTKKVYHTACKEEKLATSRENTSKLESNTNPEAQKKLQDKVEKCQQDVQKTKERYEKSLEELDKVTPQYMENMEQVFEQCQQFEDKRLSFFKELLLEVKQHLDLSTNHKFQTVYQNLEDSIQAADAEEDLKWFRSNHGPGMPMNWPQFEKVDFSRPRFHKRKSIIEWSIDLNRTLSRREKKKPSDE-VTLTGIN--------QTGDRPAKTNNNSLAVPSSTEPVGLNPFDDDDEEEEEEEV-----PAVQPKSSPVNVKKEEVISKTASSVEKTQDWSDEETGNPFGADSNGNGNPFEDEPNSPVIS----VPVRALYDYEGQEQDELSFKAGDEFTKIGEEDDQGWCKGRLKDGTVGLYPANYVEDI 503
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Cavefish
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons protein 2 [Source:NCBI gene;Acc:103038884]) HSP 1 Score: 272.707 bits (696), Expect = 6.130e-85 Identity = 162/495 (32.73%), Postives = 263/495 (53.13%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFE----------------EYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ N+LC D+ N I +R IEK+Y+ L +W+ +W +E G +YG+ ++ W EAE++SDLH +++ L+ + V+NWQ++ +HK + KE K + F AQKPWAKKLK+++ KK YH CK + + + +++ + E KK+++K+ K ++D +K K Y+ SL EL+ +Y+E M +VF + Q E +R++FFK + +++ L+LS N +YQN E++IQ D + D+ + +G P + PQFE E++ +L+ ++S+++ +D VTLT +N TG D K+ + ++ E + + ET +P + P ED SPV S V VRALYDY G E+DEL+ K GD F K+ +ED+QGWCKG+ KDG VGLYPANY E + Sbjct: 15 DSFWEIGNYKRTVKRVDDGNRLCNDLMNCIHERARIEKAYAQQLTEWAKRWRQLIEKGPQYGTVERAWCALMTEAEKVSDLHMEVKAALMAEDFEKVKNWQKDAYHKQMIG--GFKETKEADDGFRKAQKPWAKKLKEVDTTKKVYHTACKEEKLATSRENTSKLESNTNPEAQKKLQDKVEKCQQDVQKTKERYEKSLEELDKVTPQYMENMEQVFEQCQQFEDKRLSFFKELLLEVKQHLDLSTNHKFQTVYQNLEDSIQAADAEEDLKWFRSNHGPGMPMNWPQFEKVDFSRPRFHKRKSIIEWSIDLNRTLSRREKKKPSDE-VTLTGINQ-----------TG-DRPAKTNNNSASSVEKTQDWSDEETGNPFGADSNGNGNP-FEDEP----------------------------------NSPVIS----VPVRALYDYEGQEQDELSFKAGDEFTKIGEEDDQGWCKGRLKDGTVGLYPANYVEDI 455
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Sea Lamprey
Match: pacsin3 (protein kinase C and casein kinase substrate in neurons 3 [Source:ZFIN;Acc:ZDB-GENE-040426-984]) HSP 1 Score: 157.147 bits (396), Expect = 1.693e-44 Identity = 88/247 (35.63%), Postives = 144/247 (58.30%), Query Frame = 3 Query: 333 SGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLID-DIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKK 1067 +G +YGS W G EA+ +S LH DMRT+L+ DI+T ++ WQ++ FHK + KE K E F AQKPWAKKLK+++ KK Y CK + + ++ + D + + +K+ EK+ + + + +K K+ Y L +LN +Y+E+M VF++ Q E +R++FFKS+ S ++ L+LS N IY+ + I ++DP+ D+ + GA P + P FEEY+ + + +ISK+ Sbjct: 1 AGPQYGSVATAWKGLMNEADNVSTLHVDMRTQLMSKDIET-IKGWQKDAFHKQMI--GGFKETKEAEDNFRKAQKPWAKKLKEVDANKKLYQAACKEEKLAESRDNQSKTDPAQPPDVQRKLAEKVERCKAEVQKSKDRYQKVLVDLNLANPKYMEDMELVFDQCQEAEGKRLSFFKSVLSSVKVHLDLSNNDKFAAIYRELQQDISSIDPEEDLKWFRNTMGAGMPMNWPAFEEYSPDTNRTISKR 244
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000643.1 (pep scaffold:Pmarinus_7.0:GL477040:74682:76763:1 gene:ENSPMAG00000000580.1 transcript:ENSPMAT00000000643.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 147.132 bits (370), Expect = 2.175e-41 Identity = 75/199 (37.69%), Postives = 118/199 (59.30%), Query Frame = 3 Query: 150 NSAGVNT----FWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEK 734 + AGV T FW++ Y +T+RR+++ +LC D+ IQ+R +IEK YS L W+ KW + +E G +YGS ++ W EA+ +SDLH +MR ++ ++ ++NWQ++ FHK + KE K E F AQKPWAKKLK++ KK YH CK R + + +D + +Q KK+ +K+ K +D++K Sbjct: 7 DCAGVETSSESFWEVGNYKRTVRRIDDGYRLCNDLMACIQERAKIEKVYSQQLTDWTKKWKTLIERGPQYGSMERAWQALMTEADRVSDLHHEMRNQINNEDLEKIKNWQKDTFHKQLIG--GFKETKEAEDGFRKAQKPWAKKLKELEVLKKAYHLACKEERLAVSRETSTKSDPAAPPDQAKKLSDKVEKCRQDTQK 203
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Sea Lamprey
Match: ABI1 (abl interactor 1 [Source:HGNC Symbol;Acc:HGNC:11320]) HSP 1 Score: 54.6842 bits (130), Expect = 3.482e-8 Identity = 23/65 (35.38%), Postives = 41/65 (63.08%), Query Frame = 3 Query: 1404 PVFSDEDYVQ-VRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 P ++ + Y++ V A+YDY+ ++DEL+ +G + Y + D+ GW +G +G GL+P NY E + Sbjct: 386 PEWAPKIYIEKVVAVYDYVQDKDDELSFHEGSIIYVVRKNDD-GWYEGATNGHTGLFPGNYVEPI 449
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Sea Lamprey
Match: ABI1 (abl interactor 1 [Source:HGNC Symbol;Acc:HGNC:11320]) HSP 1 Score: 54.299 bits (129), Expect = 4.330e-8 Identity = 24/65 (36.92%), Postives = 43/65 (66.15%), Query Frame = 3 Query: 1404 PVFSDEDYVQ-VRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 P ++ + Y++ V A+YDY +EDEL+ ++G + Y ++ D+ GW +G +G+ GL+P NY E + Sbjct: 386 PPWAPKSYLEKVVAVYDYNKDKEDELSFQEGSIIYVIKKNDD-GWYEGTMNGQTGLFPGNYVEPI 449
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Sea Lamprey
Match: DBNL (drebrin like [Source:HGNC Symbol;Acc:HGNC:2696]) HSP 1 Score: 50.8322 bits (120), Expect = 5.144e-7 Identity = 22/54 (40.74%), Postives = 31/54 (57.41%), Query Frame = 3 Query: 1434 VRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 RALYDY ++ E++ GDL +E D+ W DG G++PANY E+V Sbjct: 302 ARALYDYQAADDTEISFDPGDLISNIEQIDDGWWNGSGPDGSRGMFPANYVELV 355
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Yeast
Match: LSB3 (Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication [Source:SGD;Acc:S000002968]) HSP 1 Score: 51.9878 bits (123), Expect = 1.579e-7 Identity = 22/53 (41.51%), Postives = 33/53 (62.26%), Query Frame = 3 Query: 1440 ALYDYIGVEEDELTLKQGDLFYKLEDEDEQG-WCKGKKDGRVGLYPANYAEIV 1595 ALY + G E +L ++GD+ L+ D Q W G+ +GR G++PANY E+V Sbjct: 407 ALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVELV 459
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Yeast
Match: LSB1 (Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication [Source:SGD;Acc:S000003368]) HSP 1 Score: 46.2098 bits (108), Expect = 4.895e-6 Identity = 22/57 (38.60%), Postives = 36/57 (63.16%), Query Frame = 3 Query: 1419 EDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 E+YV+ ALYD+ ++ +L+LK GD LE W +GK + ++G++PANY + Sbjct: 55 EEYVE--ALYDFEAQQDGDLSLKTGDKIQVLEKISPD-WYRGKSNNKIGIFPANYVK 108
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Yeast
Match: YSC84 (Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058]) HSP 1 Score: 46.9802 bits (110), Expect = 6.105e-6 Identity = 19/52 (36.54%), Postives = 32/52 (61.54%), Query Frame = 3 Query: 1440 ALYDYIGVEEDELTLKQGDLFYKLEDEDEQG-WCKGKKDGRVGLYPANYAEI 1592 ALY++ G + +L K+GD+ L+ D Q W G+ +G+ G++PANY + Sbjct: 416 ALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTNGKEGIFPANYVRV 467
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Nematostella
Match: EDO42689 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K6]) HSP 1 Score: 235.343 bits (599), Expect = 2.499e-71 Identity = 147/485 (30.31%), Postives = 239/485 (49.28%), Query Frame = 3 Query: 141 ETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 E + +A ++FWD+ Y +T++R+++ +KLC + M+ +R EIE YS+ L W+ KW +++G EYGS ++ + G EA + +H R L++D+ V+ W+ +++ KS + +KEA E F AQKPWAK L K+ + +K YH K A +D ++ QE+ KK+ + + K+ +D +K ++ Y+ L ++ D RY +MT+ F + QA E++R FFK + L++S + I+ + T Q D D+ WS+L+G P + P+FEE EL+ D + S+R G TG + + E S PS+N ++P + D E S P S++ T D P D+ V V ALYDY E+DEL+ K G++ KL + D+QGWC+G+ + R GL+PA Y E + Sbjct: 11 EETLTASSDSFWDVGNYKRTVKRVDDGSKLCDEFMKMVTERAEIEARYSAKLKVWAKKWEEVIKAGSEYGSMEEAFKGAVDEANSRASVHTQCRDDLLNDVVELVKKWKGDNYQKSMFQWKQVKEA---EEGFARAQKPWAKLLMKVMRSRKAYHNAAKATEQAKKLQIEASSDPNVPQEKFKKLTDAVEKARRDMQKCEDKYNDRLENISKDNPRYERDMTEQFERCQAFEQKRKDFFKDALMKYHSCLDVSRKSEFSGIFLHMSTTFQMADSSKDLDYWSRLHGVAMPKNWPRFEELPSELN-------RRPYDEDL----------HGSMRRG-TG--------SYENAALEYSAPSYNQVQAAPQQYN-------DAEQSNP--------FSHQDSTEEDE------------FGAIPPPMDDLAVPVLALYDYEAAEDDELSFKAGEIVTKLSERDDQGWCRGRINHRTGLFPAEYVEAL 439
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Nematostella
Match: EDO41940 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2R6]) HSP 1 Score: 187.963 bits (476), Expect = 2.601e-55 Identity = 98/289 (33.91%), Postives = 160/289 (55.36%), Query Frame = 3 Query: 168 TFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNK--NAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQF 1028 +FW + Y +T+RR+++ KLC D M+ +R EIE Y++ L WS KW L G EYGS K W+ EAE+++ +H ++++ L+ + V W+ ++HKS L + KE K+ E F AQ+PWAK+ + + KK Y+ C R+ D K N+ + ++ ++Q+KK +EKL KSE++ ++ Y ++ ++ +Y E+M VF+K QA E ER AFFK + LN+ + T IY N + +P +D+ W+ YG D P P++ Sbjct: 1 SFWQVNNYKRTVRRVDDGAKLCDDFMKMVSERAEIEALYAAKLQAWSRKWLDLLNKGPEYGSCKDSWVHVTSEAEQVAQVHINLQSTLLSRVHESVAAWKGANYHKSLL---SWKETKNAEEGFSKAQRPWAKRYDDVLKSKKAYYAAC---RARDQAEKLYNSSDPNTMKEDQIKKTKEKLMKSEREVSTTQDKYKEAVRDITNYNPKYKEDMCFVFDKLQAFEGERKAFFKQTMQGLCNALNVQQ---FTQIYNELSNKFEKTEPTADLGWWASTYGTDMPIKWPEY 280
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Nematostella
Match: EDO43872 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXM7]) HSP 1 Score: 70.8626 bits (172), Expect = 5.753e-13 Identity = 109/516 (21.12%), Postives = 214/516 (41.47%), Query Frame = 3 Query: 168 TFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKN-------AVNDTSIS--QEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGAD-FPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSF-NMETSSPLST-------------SALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIK--ESP--------------VFSDEDYV--QVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 +FW+ K Y + + + C +I + +R +IE SY+ SL K S K L + G+ K W E +D+H+ + +L + + K+ + Q+ K K +E E + A K ++ +L + K H + K V + Q ++ AV+D I+ + ++KK E KS+KD ++ + + E ++Y + K +E+ER+ K MFS +L + L +Y++ ++ + P D+ + + G+ P ++ Y ++L N+ +N++ I + + ++ K+ T ++TP + N ET + ++ ++ +L+ L +P + + TR+ +Q ++ + P+ +SP F + V Q +A+YDY + DELT+ GD+ D GW +G + + G++PA+Y E Sbjct: 7 SFWEQKGYEELRKSCRQGSDFCKEIAAIFNERSKIELSYADSLSKLSVKAQKLLAKDV-VGTLKSSWEKISWNIESEADIHRTLANQLHGEAAKQI---------KAFVETQS-KTRKPVEVEVEKAYKNFSDRLSDSLKKKGASHSKSKEVETLHDQMEDTKQGKGKAVSDKDITKLEAKIKKGMESAIKSDKDYREMYMKTERTRLEWEATMSKYCQTCEK-------LEEERVGHLKDMFSLYGNML-AAVIPELQQVYESIQHEASQISPKEDVNTIADVKGSPRGPSEQTLYDCYEEDLE----------NNFNFERRKEALNAK-IKILASELEKEKKAKTGVVNLMDTYSATPEYCNQETQNDVAMQITHVNAVIDSLQASSYKLQCSLAKLTGNSQPQHPLMDYITSTRD--KQGTVQSTLRKPLDLVKSPGGYESDDQLDDEFDDFQPDGTVLCQCKAIYDYQATQSDELTIHPGDIITVTARLD-NGWWQGDLNNQQGIFPASYVE 489
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Nematostella
Match: EDO34808 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNC2]) HSP 1 Score: 70.0922 bits (170), Expect = 6.684e-13 Identity = 103/501 (20.56%), Postives = 205/501 (40.92%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTI------RRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEA-KSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQ-----------LKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLY--GADFPFSTPQFEEY-----TQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAE 1589 V+ FW ++ T +R+ + + C ++ ++ R +IE+ Y SL + + TS E+ E G+ K W E E I H + +L+D ++ ++ ++ +N KE K LE +Q+ + +++ K+ Y Q+C+ + D K +V+ + +E+ +K +R + S + + Y +S+ L+ + EM N Q +E+ER+AF ++ + +++ K + ++Y+ +++ + D DI + + G++ P S +E Y +Q+ +S +N+ +LT RD + + P A+ P+ E ++ L T+ + + PP KP + P E Y RALY+Y + EL+ K D+ L +ED+ WC G+ +G+ G++P + + Sbjct: 5 VDCFWG-TEFTSTAGFDALSKRMRDGKQTCQEMEEFVKQRADIEEKYGKSLMRLAK--TS--EAKDEIGTLKSSWDSLRNETENIGKAHVALAQQLLDSLEKGLQEFR-----------ENQKETRKKLEDSVKRSQRNKKTCYENLHKLKRTYEQKCREKEAADDALKKSVSMAAKDEEKTLHSSIVYGHTTEKAPVLVRSPKLSSVEHDSAYQTSVRVLDDTRVVWEREMATCCNVFQNLEEERIAFLRNWMWLYANLGSINCVK-VDEMYEVVRQSLEGCNVDQDIKLFISMRQTGSERP-SHIDYENYYMVQSSQKTSPLSGGSVNIGGPIPGSLTH---------------SRDMV--QVGRPGGRLPAALPAVPTEENADLYTT--------VNEVLPPQKPTARV---------------------------PARPKERY--FRALYEYEAQGDQELSFKASDIIRFLYEEDDT-WCCGELNGKKGMFPKEFVD 432
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Nematostella
Match: EDO38710 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC74]) HSP 1 Score: 51.6026 bits (122), Expect = 1.623e-7 Identity = 28/71 (39.44%), Postives = 43/71 (60.56%), Query Frame = 3 Query: 1389 PIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDE--DEQGWCKGKKDGRVGLYPANYAEIV 1595 P K+ P ++E ++ + YDY EDEL LK GD+ ++ E D GW +G+ DG+ GL+P N+ EI+ Sbjct: 147 PEKQPP--AEEPVLRAKVTYDYEQQNEDELELKVGDIITIVKKEVFDTPGWMEGELDGKTGLFPDNFVEIL 215
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Medaka
Match: pacsin1b (protein kinase C and casein kinase substrate in neurons protein 1 [Source:NCBI gene;Acc:101158350]) HSP 1 Score: 297.36 bits (760), Expect = 1.132e-94 Identity = 169/481 (35.14%), Postives = 265/481 (55.09%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDY-VQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ N+LC D+ N IQ+R +IEK+Y+ L +WS +W ++ G +YG+ ++ W+ EA+++SDLH+D++ LI+ V+NWQ++ +HK + KE K E F AQKPWAKKLK++ KK YH CK R + N+ + S+ EQ KK++EKL K ++DS+K + Y+ +L EL+ +Y E M +VF + Q E+ R++F K + ++ LNL+EN++ +Y++ E TI + P D+ +S +G + PQFEEY +L HSI+KK+ + + LT V + + + + GD G S +A TPS +D Q + ++ ++T +P D V+VRALYDY G E+DELT K G+ KLEDEDEQGWCKG+ D G++GLYPANY E + Sbjct: 14 TDSFWEVGNYKRTVKRIDDGNRLCNDLMNCIQERAKIEKAYAQQLTEWSKRWRQMVDRGPQYGTVERAWMALMTEADKVSDLHQDVKNSLINLDFEKVKNWQKDSYHKQMMG--GFKETKEAEEGFKKAQKPWAKKLKELEAAKKSYHMTCKEERLAVTREANSRAEASVPAEQQKKLQEKLDKCKQDSQKAREKYEKALEELSNSTPQYTESMEQVFEQCQQFEERRLSFIKEVLLDVKHHLNLTENQSYAAVYRDLEQTISSASPQEDLRWFSSSHGPGMHMNWPQFEEYNPDLAHSIAKKE-KIGKGDKIKLTHVTPSVQHS--QGGDRGS-------VSSYEKNQAYTPSTEW---------------------------------------SDEDQMAPNSGSDTNGGSNPFEEDVGRGVRVRALYDYEGQEQDELTFKAGEELTKLEDEDEQGWCKGRLDNGKLGLYPANYVEAI 443
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Medaka
Match: pacsin1b (protein kinase C and casein kinase substrate in neurons protein 1 [Source:NCBI gene;Acc:101158350]) HSP 1 Score: 297.36 bits (760), Expect = 1.132e-94 Identity = 169/481 (35.14%), Postives = 265/481 (55.09%), Query Frame = 3 Query: 162 VNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQEL-HSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDY-VQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKD-GRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ N+LC D+ N IQ+R +IEK+Y+ L +WS +W ++ G +YG+ ++ W+ EA+++SDLH+D++ LI+ V+NWQ++ +HK + KE K E F AQKPWAKKLK++ KK YH CK R + N+ + S+ EQ KK++EKL K ++DS+K + Y+ +L EL+ +Y E M +VF + Q E+ R++F K + ++ LNL+EN++ +Y++ E TI + P D+ +S +G + PQFEEY +L HSI+KK+ + + LT V + + + + GD G S +A TPS +D Q + ++ ++T +P D V+VRALYDY G E+DELT K G+ KLEDEDEQGWCKG+ D G++GLYPANY E + Sbjct: 14 TDSFWEVGNYKRTVKRIDDGNRLCNDLMNCIQERAKIEKAYAQQLTEWSKRWRQMVDRGPQYGTVERAWMALMTEADKVSDLHQDVKNSLINLDFEKVKNWQKDSYHKQMMG--GFKETKEAEEGFKKAQKPWAKKLKELEAAKKSYHMTCKEERLAVTREANSRAEASVPAEQQKKLQEKLDKCKQDSQKAREKYEKALEELSNSTPQYTESMEQVFEQCQQFEERRLSFIKEVLLDVKHHLNLTENQSYAAVYRDLEQTISSASPQEDLRWFSSSHGPGMHMNWPQFEEYNPDLAHSIAKKE-KIGKGDKIKLTHVTPSVQHS--QGGDRGS-------VSSYEKNQAYTPSTEW---------------------------------------SDEDQMAPNSGSDTNGGSNPFEEDVGRGVRVRALYDYEGQEQDELTFKAGEELTKLEDEDEQGWCKGRLDNGKLGLYPANYVEAI 443
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Medaka
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:NCBI gene;Acc:101172296]) HSP 1 Score: 280.796 bits (717), Expect = 8.944e-88 Identity = 155/483 (32.09%), Postives = 264/483 (54.66%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETE-TPIKESP---VFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ ++LC+D+ + +R IEKSY+ L +W +W +E G +YGS ++ W C EAE++S+LH +++ +L+ + ++NWQ++ +HK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ +++ + E LKK++EK+ K +++ +K K Y+ SL EL+ +Y+E M +VF + Q E +R+ FFK + +++ L+LS N IY +TI D + D+ + +G P + PQFE+++ +++ ++S+++ GVTLT +N +++ T S+ P+ + F + + + +K S + D N +A + P +E P V S V V+ALYDY G E+DEL+ K GD F K+ +ED+QGWCKG+ KDG +GLYPANY E + Sbjct: 15 DSFWEVGNYKRTVKRVDDGHRLCSDLMTCLHERARIEKSYAQQLTEWGKRWRQLIEKGPQYGSLERAWAALCTEAEKVSELHMEVKAQLMGEDYEKLKNWQKDAYHKQMI--GGFKETKEADDGFRKAQKPWAKKLKEVETMKKTYHAACKEEKLASSRESNSKLESNNNPETLKKLQEKVEKCQQEVQKTKERYEKSLEELDKLTPQYMENMEQVFEQMQQFEDKRICFFKELLLEVKQHLDLSTNHRFQTIYHTLADTITATDVEEDLKWFRFNHGPGMPMNWPQFEDWSIDINRTLSRREKK--KPEGVTLTGINQTGADQPVQAAKT-----SSSLTVPTNTAPVGSNPFEEDEDEEEMAEEPETTVISISVNKEEIKTASSTEKTPDWSDEDTAGNPFAANGDGNPFEEEPASLVIS----VPVKALYDYEGQEQDELSFKAGDEFTKIGEEDDQGWCKGRLKDGHIGLYPANYVEEI 484
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Medaka
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:NCBI gene;Acc:101172296]) HSP 1 Score: 273.863 bits (699), Expect = 7.387e-85 Identity = 158/497 (31.79%), Postives = 260/497 (52.31%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEY-TQELHSISKKK-------LNLT-------NDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETE-TPIKESP---VFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ ++LC+D+ + +R IEKSY+ L +W +W +E G +YGS ++ W C EAE++S+LH +++ +L+ + ++NWQ++ +HK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ +++ + E LKK++EK+ K +++ +K K Y+ SL EL+ +Y+E M +VF + Q E +R+ FFK + +++ L+LS N IY +TI D + D+ + +G P + PQFE + L S ++ +N T GVTLT +N +++ T S+ P+ + F + + + +K S + D N +A + P +E P V S V V+ALYDY G E+DEL+ K GD F K+ +ED+QGWCKG+ KDG +GLYPANY E + Sbjct: 15 DSFWEVGNYKRTVKRVDDGHRLCSDLMTCLHERARIEKSYAQQLTEWGKRWRQLIEKGPQYGSLERAWAALCTEAEKVSELHMEVKAQLMGEDYEKLKNWQKDAYHKQMI--GGFKETKEADDGFRKAQKPWAKKLKEVETMKKTYHAACKEEKLASSRESNSKLESNNNPETLKKLQEKVEKCQQEVQKTKERYEKSLEELDKLTPQYMENMEQVFEQMQQFEDKRICFFKELLLEVKQHLDLSTNHRFQTIYHTLADTITATDVEEDLKWFRFNHGPGMPMNWPQFETLDSSHLASFRRRSILDWSIDINRTLSRREKKKPEGVTLTGINQTGADQPVQAAKT-----SSSLTVPTNTAPVGSNPFEEDEDEEEMAEEPETTVISISVNKEEIKTASSTEKTPDWSDEDTAGNPFAANGDGNPFEEEPASLVIS----VPVKALYDYEGQEQDELSFKAGDEFTKIGEEDDQGWCKGRLKDGHIGLYPANYVEEI 500
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Medaka
Match: pacsin2 (protein kinase C and casein kinase substrate in neurons 2 [Source:NCBI gene;Acc:101172296]) HSP 1 Score: 265.774 bits (678), Expect = 1.808e-82 Identity = 156/483 (32.30%), Postives = 260/483 (53.83%), Query Frame = 3 Query: 165 NTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELH-SISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETE-TPIKESP---VFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGK-KDGRVGLYPANYAEIV 1595 ++FW++ Y +T++R+++ ++LC+D+ + +R IEKSY+ L +W +W +E G +YGS ++ W C EAE++S+LH +++ +L+ + ++NWQ++ +HK + KE K + F AQKPWAKKLK++ KK YH CK + + N+ +++ + E LKK++EK+ K +++ +K K Y+ SL EL+ +Y+E M +VF + Q E +R+ FFK + +++ L+LS N IY +TI D + D+ + +G P + PQFE+++ +++ ++S+++ GVTLT +N T A P ++ + S+++ PD D D N +A + P +E P V S V V+ALYDY G E+DEL+ K GD F K+ +ED+QGWCKG+ KDG +GLYPANY E + Sbjct: 15 DSFWEVGNYKRTVKRVDDGHRLCSDLMTCLHERARIEKSYAQQLTEWGKRWRQLIEKGPQYGSLERAWAALCTEAEKVSELHMEVKAQLMGEDYEKLKNWQKDAYHKQMIG--GFKETKEADDGFRKAQKPWAKKLKEVETMKKTYHAACKEEKLASSRESNSKLESNNNPETLKKLQEKVEKCQQEVQKTKERYEKSLEELDKLTPQYMENMEQVFEQMQQFEDKRICFFKELLLEVKQHLDLSTNHRFQTIYHTLADTITATDVEEDLKWFRFNHGPGMPMNWPQFEDWSIDINRTLSRREKK--KPEGVTLTGINQ---------------------------TGADQP---VQAAKTSSSASSTEKTPDWSDE-------------------DTAGNPFAANGDGNPFEEEPASLVIS----VPVKALYDYEGQEQDELSFKAGDEFTKIGEEDDQGWCKGRLKDGHIGLYPANYVEEI 440
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Planmine SMEST
Match: SMESG000054559.1 (SMESG000054559.1) HSP 1 Score: 1026.16 bits (2652), Expect = 0.000e+0 Identity = 492/494 (99.60%), Postives = 492/494 (99.60%), Query Frame = 3 Query: 114 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEY QELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDS GKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV Sbjct: 1 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYIQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSTGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 494
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Planmine SMEST
Match: SMESG000054559.1 (SMESG000054559.1) HSP 1 Score: 915.605 bits (2365), Expect = 0.000e+0 Identity = 448/494 (90.69%), Postives = 448/494 (90.69%), Query Frame = 3 Query: 114 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEY QELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDS GKSMASPSTGTEASTPSFNMETSSPLSTSALR ESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV Sbjct: 1 MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYIQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGDTGRDSTGKSMASPSTGTEASTPSFNMETSSPLSTSALR--------------------------------------------ESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 450
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Planmine SMEST
Match: SMESG000056577.1 (SMESG000056577.1) HSP 1 Score: 379.793 bits (974), Expect = 7.407e-127 Identity = 208/472 (44.07%), Postives = 290/472 (61.44%), Query Frame = 3 Query: 183 KQYVKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGD-TGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 KQY++TI+RLEN+ KLC D+ MI +R EIEK YSSSL KW+ KW YL+SG EYG+ K W C E+ EI+DLH +RT+LID+ Q +++ WQ++H+HK +P Q KE KSLE+EF+ QKPWAKKLKK KK+Y CK +S ++Q +NA ND++++ +Q+KK+EEK RK+EK+ EK K Y +SLN+L G+ RY+E+M K F K+Q+ME+ER+ +FK F I+ ILNLS+ L +IY++ + I ++ + D+ WS G+ F PQFEEYT EL IS K+ + N GV L V SI + + D +S+ S + PS++ E +P S + +E + SA P S+T D++ V+VRALYDY EEDELTL G++F KL +EDEQGWC G++DG VGLYPANYA+ + Sbjct: 3 KQYMRTIKRLENSYKLCQDLMTMISERAEIEKHYSSSLKKWNGKWMGYLDSGAEYGTAKHGWQSLCTESLEIADLHAIIRTQLIDESQPEIKKWQKDHYHKPAIPTQQFKEVKSLETEFETNQKPWAKKLKKSIIMKKDYFAACKQEKSSNLQLQNAKNDSTVNPDQIKKIEEKYRKAEKEVEKTKASYQASLNDLEGESGRYMEDMEKTFKKAQSMEQERIEYFKETFENIRMILNLSKTDKLHEIYEHCKLGISEMNSEVDLKNWSMTNGSAMVFMIPQFEEYTPELSGISNKRKAVLN-PGVVLKGV------TSIDNDKMSNNDKSNESLNEASKYVDKRLPSYD-EAMNPFSANEENGVE--FKISADPY---------DSITEIDNKPG---------------------VKVRALYDYNSQEEDELTLVAGEIFEKLTEEDEQGWCTGRRDGVVGLYPANYADPI 434
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Planmine SMEST
Match: SMESG000056577.1 (SMESG000056577.1) HSP 1 Score: 373.629 bits (958), Expect = 1.650e-124 Identity = 205/469 (43.71%), Postives = 287/469 (61.19%), Query Frame = 3 Query: 192 VKTIRRLENANKLCTDICNMIQDRVEIEKSYSSSLHKWSTKWTSYLESGIEYGSTKQCWLGFCREAEEISDLHKDMRTRLIDDIQTDVRNWQREHFHKSTLPPQNLKEAKSLESEFDIAQKPWAKKLKKMNQCKKEYHQQCKMVRSYDVQNKNAVNDTSISQEQLKKMEEKLRKSEKDSEKLKNLYDSSLNELNGDCNRYVEEMTKVFNKSQAMEKERMAFFKSMFSRIQKILNLSENKNLTDIYQNFENTIQTLDPDSDIAQWSQLYGADFPFSTPQFEEYTQELHSISKKKLNLTNDSGVTLTAVNMNSRQASIRSGD-TGRDSMGKSMASPSTGTEASTPSFNMETSSPLSTSALRRLEPDLEDSAPPMKPCRSISSNKSVTRNDHRQNSISAETETPIKESPVFSDEDYVQVRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYAEIV 1595 ++TI+RLEN+ KLC D+ MI +R EIEK YSSSL KW+ KW YL+SG EYG+ K W C E+ EI+DLH +RT+LID+ Q +++ WQ++H+HK +P Q KE KSLE+EF+ QKPWAKKLKK KK+Y CK +S ++Q +NA ND++++ +Q+KK+EEK RK+EK+ EK K Y +SLN+L G+ RY+E+M K F K+Q+ME+ER+ +FK F I+ ILNLS+ L +IY++ + I ++ + D+ WS G+ F PQFEEYT EL IS K+ + N GV L V SI + + D +S+ S + PS++ E +P S + +E + SA P S+T D++ V+VRALYDY EEDELTL G++F KL +EDEQGWC G++DG VGLYPANYA+ + Sbjct: 1 MRTIKRLENSYKLCQDLMTMISERAEIEKHYSSSLKKWNGKWMGYLDSGAEYGTAKHGWQSLCTESLEIADLHAIIRTQLIDESQPEIKKWQKDHYHKPAIPTQQFKEVKSLETEFETNQKPWAKKLKKSIIMKKDYFAACKQEKSSNLQLQNAKNDSTVNPDQIKKIEEKYRKAEKEVEKTKASYQASLNDLEGESGRYMEDMEKTFKKAQSMEQERIEYFKETFENIRMILNLSKTDKLHEIYEHCKLGISEMNSEVDLKNWSMTNGSAMVFMIPQFEEYTPELSGISNKRKAVLN-PGVVLKGV------TSIDNDKMSNNDKSNESLNEASKYVDKRLPSYD-EAMNPFSANEENGVE--FKISADPY---------DSITEIDNKPG---------------------VKVRALYDYNSQEEDELTLVAGEIFEKLTEEDEQGWCTGRRDGVVGLYPANYADPI 429
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Planmine SMEST
Match: SMESG000004952.1 (SMESG000004952.1) HSP 1 Score: 48.521 bits (114), Expect = 3.206e-6 Identity = 21/51 (41.18%), Postives = 30/51 (58.82%), Query Frame = 3 Query: 1434 VRALYDYIGVEEDELTLKQGDLFYKLEDEDEQGWCKGKKDGRVGLYPANYA 1586 VRA+Y Y DEL+ ++GDL Y + Q W K + +G+ GL P+NY Sbjct: 17 VRAIYSYEAQSADELSFEEGDLLYIFDMISSQDWWKARANGKEGLIPSNYV 67 The following BLAST results are available for this feature:
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase C and casein kinase substrate in neurons protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30030763 ID=SMED30030763|Name=Protein kinase C and casein kinase substrate in neurons protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1730bpback to top protein sequence of SMED30030763-orf-1 >SMED30030763-orf-1 ID=SMED30030763-orf-1|Name=SMED30030763-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=495bp MSNSFEFEGETSNSAGVNTFWDLKQYVKTIRRLENANKLCTDICNMIQDRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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