Tripartite motif-containing protein 2

Overview


Name	Tripartite motif-containing protein 2
Smed ID	SMED30030752
Length (bp)	2122

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Tripartite motif-containing protein 2 (SMED30030752) t-SNE clustered cells

Violin plots show distribution of expression levels for Tripartite motif-containing protein 2 (SMED30030752) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tripartite motif-containing protein 2 (SMED30030752) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tripartite motif-containing protein 2 (SMED30030752) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30030752

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
cephalic ganglia	SMED30030752	SMESG000023375.1	dd_Smed_v4_8395_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30030752	SMESG000023375.1	dd_Smed_v4_8395_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30030752	SMESG000023375.1	dd_Smed_v4_8395_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Human
Match: TRIM56 (tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028])

HSP 1 Score: 128.257 bits (321), Expect = 5.072e-30
Identity = 75/285 (26.32%), Postives = 127/285 (44.56%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNN--RKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL------------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQ----EIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIR 1242
            L + +  + L CKICLE  + PK+L CLHT+C +CL           + +D     CP CR+   +P  GV     NF V  L +++K R  +  DL + +      C +C  +        A  +C+DC+  LC+ C + HR T+ T  H + DL                   C  HP E++RF C+PC   +C  C  + H DH      EAV   +  +E  L+       E+ +   ++   +  + +       Q++E A  ++  +  ++ ++L ++R
Sbjct:   10 LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCL----------AQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKAR--ACGDLRAGKPA----CALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLR 278

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Human
Match: TRIM56 (tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028])

HSP 1 Score: 121.709 bits (304), Expect = 8.909e-30
Identity = 73/280 (26.07%), Postives = 124/280 (44.29%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNN--RKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL------------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEI 1239
            L + +  + L CKICLE  + PK+L CLHT+C +CL           + +D     CP CR+   +P  GV     NF V  L +++K R  +  DL + +      C +C  +        A  +C+DC+  LC+ C + HR T+ T  H + DL                   C  HP E++RF C+PC   +C  C  + H DH      EAV   +  +E        +++  +  L ++    ++ K    +++E A+++  ++      +L  +
Sbjct:   10 LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCL----------AQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKAR--ACGDLRAGKPA----CALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEG-------LLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRAL 266

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Human
Match: TRIM45 (tripartite motif containing 45 [Source:HGNC Symbol;Acc:HGNC:19018])

HSP 1 Score: 104.76 bits (260), Expect = 9.116e-23
Identity = 75/322 (23.29%), Postives = 137/322 (42.55%), Query Frame = 1

Query:  475 CKICLENYKQPKSLSCLHTFCAECLEN-------HIQG--EVTYKKYSDYREF-----------TCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKIN----NVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVIL 1347
            C +CL  +K P+ L CLHT C  CLE         I+G    T  + S ++E             CP+C  +  LPMGGV+ L  + +  +   +   R +               C +C       RE + +C  C   LC  C + HR+ K T  H++ DL        I   ++C +HP E +R FC+ C   +C  C   EH +H     +  + K+   + + L  +Q  +   E  L++I+     +++ +++    ++  +   I  I     +LL+++ ++       +   K+ +E  L++++      E +L
Sbjct:   29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEG----------QGLVCDLCND-----REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Human
Match: TRIM45 (tripartite motif containing 45 [Source:HGNC Symbol;Acc:HGNC:19018])

HSP 1 Score: 104.76 bits (260), Expect = 9.231e-23
Identity = 75/322 (23.29%), Postives = 137/322 (42.55%), Query Frame = 1

Query:  475 CKICLENYKQPKSLSCLHTFCAECLEN-------HIQG--EVTYKKYSDYREF-----------TCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKIN----NVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVIL 1347
            C +CL  +K P+ L CLHT C  CLE         I+G    T  + S ++E             CP+C  +  LPMGGV+ L  + +  +   +   R +               C +C       RE + +C  C   LC  C + HR+ K T  H++ DL        I   ++C +HP E +R FC+ C   +C  C   EH +H     +  + K+   + + L  +Q  +   E  L++I+     +++ +++    ++  +   I  I     +LL+++ ++       +   K+ +E  L++++      E +L
Sbjct:   29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEG----------QGLVCDLCND-----REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Human
Match: TRIM2 (tripartite motif containing 2 [Source:HGNC Symbol;Acc:HGNC:15974])

HSP 1 Score: 96.2857 bits (238), Expect = 6.288e-20
Identity = 79/326 (24.23%), Postives = 133/326 (40.80%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRH-----------KESQLLEEIRNLYG----------DNMIDIIESKSVMENQLSELKNTCNMAEVILQRK 1356
            + ++I  + LIC ICLE YK PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L +NF + +L +++++   S     +EES+                E  T       L C N                             H    + F+C+ C+  +C  CT  EH++H      + V ++K+ ++ QL    +       +L +I++  Q I    +Q+    + ++ +I             ++S LL E+   YG          D ++   ES     N  ++  N     EV+L +K
Sbjct:   12 VVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGS----NAEESSI--------------LETVTAVAAGKPLSCPN-----------------------------HDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNK-------RLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKK 275

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Celegans
Match: nhl-2 (NHL (Ring finger b-box coiled coil) domain containing [Source:UniProtKB/TrEMBL;Acc:Q19818])

HSP 1 Score: 75.485 bits (184), Expect = 8.165e-14
Identity = 90/400 (22.50%), Postives = 166/400 (41.50%), Query Frame = 1

Query:  271 EKKHERPMSWI------PTSDFLKTFNGDTLGSNLNDAEIFKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAEC----LENHIQGE---VTYKKYSDYREFTC----PLCRKRTTLPMGGVRKLP-----------DNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSL---FDLNIEN------DVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRN----LYGDNMIDIIESKSVMENQLSEL--KNTCNMAEV 1341
            +K  +RP S +      P +    T N  T   +LN  +  +STS SP    +               +D+   C  C +++++P+ L CLH+ C +C    L+ H+Q +   +  KK +      C    P  ++R T P  GV + P             +V A L + ++  +    ++    +     C  C+     ++EA   C  CS  LC NCT  H    + Q H++    DL           V+C  H  + +R+ C  C+   C  C   +H +H+I   NE V+          +  +++ S  +    K NN    + S  ++ +++  +  +  +++  +  EE+RN     Y  ++ D+ E++   E+ + E+  K+  N A V
Sbjct:    2 KKAADRPTSAVNGRHESPATSTNNTQNSGT--PSLNGQDPLRSTSSSPLFGTE------------PLPEDDHASCPYCQQDFRKPRVLDCLHSMCEDCIIAQLDGHLQAKSAAIEEKKRATAAMLDCELETPKVKERPTPP--GVIRCPICSQESHVGNDVRYVHAMLLDFVRLAEMKEVEVEKMVAHHRKPCTACKS----EQEAIAFCDQCSSDLCENCTTAHTVMNLFQGHTVTTFADLRQPGAHPELRQVMCSTH-NQHMRYLCAACETAACKQCLEVDHLNHKIIDINELVIN---------AIREDVTSTVDRVEKKYNNSVADMNSLPDKSQQLNEQYEIA-KYRVDKHYEELRNSIEEAYQKSVNDLEEARIRQESNIDEMYRKSQVNEARV 370

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Celegans
Match: nhl-1 (RING finger protein nhl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q03601])

HSP 1 Score: 68.1662 bits (165), Expect = 1.658e-11
Identity = 41/135 (30.37%), Postives = 66/135 (48.89%), Query Frame = 1

Query:  460 DELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEM-IKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIH 861
            ++LL C ICL+ YKQPK L C HTFC  CLE+           + +R   CP CR    +P  GV+    N+ +    E+ ++   +S  ++  EE    +  + C K+ + K + +  C  C +  C+ C + H
Sbjct:   38 EQLLTCPICLDRYKQPKLLPCQHTFCYPCLESCAD--------TLHRNLKCPECRAEHNIPYDGVKAFQPNYTLTGFLEIHLQATPESAAEI--EEYIHRYNLERC-KICDEKADCE-PCAHCDRKACKECRQTH 160

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Celegans
Match: nhl-1 (RING finger protein nhl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q03601])

HSP 1 Score: 68.1662 bits (165), Expect = 1.784e-11
Identity = 41/135 (30.37%), Postives = 66/135 (48.89%), Query Frame = 1

Query:  460 DELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEM-IKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIH 861
            ++LL C ICL+ YKQPK L C HTFC  CLE+           + +R   CP CR    +P  GV+    N+ +    E+ ++   +S  ++  EE    +  + C K+ + K + +  C  C +  C+ C + H
Sbjct:   38 EQLLTCPICLDRYKQPKLLPCQHTFCYPCLESCAD--------TLHRNLKCPECRAEHNIPYDGVKAFQPNYTLTGFLEIHLQATPESAAEI--EEYIHRYNLERC-KICDEKADCE-PCAHCDRKACKECRQTH 160

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Celegans
Match: arc-1 (E3 ubiquitin-protein ligase arc-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09654])

HSP 1 Score: 56.225 bits (134), Expect = 5.449e-8
Identity = 78/339 (23.01%), Postives = 133/339 (39.23%), Query Frame = 1

Query:  475 CKICLENY------KQPKSLS-CLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFE-------MIKKRKDSVT-DLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIEND--VICKIHPEESVRFFCK--PCQA---CICVLC-TFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQII------------KSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIES-KSVMENQLSELKNTCNMAE--------VILQRKD 1359
            C +C E Y      K P+ L+ C HT C  C  + I G  +           CP  R  T +P G ++ L  NF +  L E       +++K  + V  D  S+E   N  C       + +  A   C  C   LC  C+E    T V  +H    L  +    V C++H    V F CK   C      +C++C  +  H  H      + V   +  + + L    E+  Q E   + +++++ +I            + T  +++    +L   +   E   +E + + Y  N ++ +++ K  +E   S++ NTC   +         IL RKD
Sbjct:    6 CNVCNEEYSARDPLKCPRVLTGCGHTICHNCAIS-IAGRNS--------SIFCPFDRTATQIPGGDLQNLKKNFALLELLEKIADGGGLLEKSGEVVKFDRYSKERLLNLECD-----EDSEHVAVIYCTVCDSNLCERCSESTHSTNVLSKHRRIPLTEKPPPLVHCRLHSSYVVEFVCKELSCDTESPLMCMMCRDYGRHKGHSHVLIEKEVEDLREKVREHLG---ELSKQSETIGNALHSIDSVIHELTPGQEDGSLEETRQEVRNHFRRLRTALDRDEEDAVETV-DRYARNRVESLQTQKERLEAISSKIGNTCTTLQKALIMERGKILDRKD 326

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Celegans
Match: nhl-3 (NHL (Ring finger b-box coiled coil) domain containing [Source:UniProtKB/TrEMBL;Acc:H2L0K3])

HSP 1 Score: 51.6026 bits (122), Expect = 1.667e-6
Identity = 30/115 (26.09%), Postives = 51/115 (44.35%), Query Frame = 1

Query:  445 AQEIQDELLICKICLENY----KQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIK-KRKDSVTDLTSEESTTNFFCQIC 774
              +  +  L C  CL  Y    ++PK L C H+ C  C+    +        +      CPLCR+   +P GGV   P  F +  L ++++ +RKD V   ++  +    +C+ C
Sbjct:   15 VDDFSETFLTCSTCLYTYDGNTRKPKLLPCSHSVCLFCVTQLAE----LSPETQPPTLRCPLCREVCPIPAGGVILFPAAFFINQLLDVMQIQRKDVVPSCSNHPTDQLLYCETC 125

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Fly
Match: mei-P26 (gene:FBgn0026206 transcript:FBtr0474151)

HSP 1 Score: 101.679 bits (252), Expect = 8.553e-22
Identity = 78/331 (23.56%), Postives = 143/331 (43.20%), Query Frame = 1

Query:  454 IQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYS--------DYRE---------FTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLF-----------DLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEH--SDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMAS------KLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAE 1338
            I+D   +CK+C      P+ LSCLH FC +CL+  +  +               D  E           CP+C++ T L   G++ LP +++V ++ ++        ++L SE    +  C  C+     K EA ++C DC+  LC  C   H+  +  + H +             L I   V C  H  E+++++C  CQ   C  C  ++H  SDH       A    ++D+E+ LS + +    C    S + +    ++S  + +++         K +LE    + Q+L E+  L+ D  + I++    MEN + +L++     +
Sbjct:  154 IKDGDKLCKLCSLRLVMPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSEHQNRLSAVFIECPVCKQETPLGPKGIKALPCDYIVTNILDL--------SNLESE----HIVCTSCKS----KEEAISRCNDCANFLCNGCDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSENLKYYCFTCQVPTCNDCLLSDHKGSDHHYETATVAEQAVRADLEETLSDTLKKADYCNDAGSNLGSALTELQSQHDTVRQQIEDAYKCYKRMLE--SIKDQMLNELGRLHSDRELKIMDLMQSMENTMGKLQHAAQFGQ 466

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Fly
Match: mei-P26 (gene:FBgn0026206 transcript:FBtr0333474)

HSP 1 Score: 101.679 bits (252), Expect = 9.677e-22
Identity = 78/331 (23.56%), Postives = 143/331 (43.20%), Query Frame = 1

Query:  454 IQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYS--------DYRE---------FTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLF-----------DLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEH--SDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMAS------KLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAE 1338
            I+D   +CK+C      P+ LSCLH FC +CL+  +  +               D  E           CP+C++ T L   G++ LP +++V ++ ++        ++L SE    +  C  C+     K EA ++C DC+  LC  C   H+  +  + H +             L I   V C  H  E+++++C  CQ   C  C  ++H  SDH       A    ++D+E+ LS + +    C    S + +    ++S  + +++         K +LE    + Q+L E+  L+ D  + I++    MEN + +L++     +
Sbjct:  154 IKDGDKLCKLCSLRLVMPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSEHQNRLSAVFIECPVCKQETPLGPKGIKALPCDYIVTNILDL--------SNLESE----HIVCTSCKS----KEEAISRCNDCANFLCNGCDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSENLKYYCFTCQVPTCNDCLLSDHKGSDHHYETATVAEQAVRADLEETLSDTLKKADYCNDAGSNLGSALTELQSQHDTVRQQIEDAYKCYKRMLE--SIKDQMLNELGRLHSDRELKIMDLMQSMENTMGKLQHAAQFGQ 466

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Fly
Match: mei-P26 (gene:FBgn0026206 transcript:FBtr0340341)

HSP 1 Score: 101.679 bits (252), Expect = 9.677e-22
Identity = 78/331 (23.56%), Postives = 143/331 (43.20%), Query Frame = 1

Query:  454 IQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYS--------DYRE---------FTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLF-----------DLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEH--SDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMAS------KLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAE 1338
            I+D   +CK+C      P+ LSCLH FC +CL+  +  +               D  E           CP+C++ T L   G++ LP +++V ++ ++        ++L SE    +  C  C+     K EA ++C DC+  LC  C   H+  +  + H +             L I   V C  H  E+++++C  CQ   C  C  ++H  SDH       A    ++D+E+ LS + +    C    S + +    ++S  + +++         K +LE    + Q+L E+  L+ D  + I++    MEN + +L++     +
Sbjct:  154 IKDGDKLCKLCSLRLVMPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSEHQNRLSAVFIECPVCKQETPLGPKGIKALPCDYIVTNILDL--------SNLESE----HIVCTSCKS----KEEAISRCNDCANFLCNGCDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSENLKYYCFTCQVPTCNDCLLSDHKGSDHHYETATVAEQAVRADLEETLSDTLKKADYCNDAGSNLGSALTELQSQHDTVRQQIEDAYKCYKRMLE--SIKDQMLNELGRLHSDRELKIMDLMQSMENTMGKLQHAAQFGQ 466

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Fly
Match: mei-P26 (gene:FBgn0026206 transcript:FBtr0333473)

HSP 1 Score: 101.679 bits (252), Expect = 9.688e-22
Identity = 78/331 (23.56%), Postives = 143/331 (43.20%), Query Frame = 1

Query:  454 IQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYS--------DYRE---------FTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLF-----------DLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEH--SDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMAS------KLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAE 1338
            I+D   +CK+C      P+ LSCLH FC +CL+  +  +               D  E           CP+C++ T L   G++ LP +++V ++ ++        ++L SE    +  C  C+     K EA ++C DC+  LC  C   H+  +  + H +             L I   V C  H  E+++++C  CQ   C  C  ++H  SDH       A    ++D+E+ LS + +    C    S + +    ++S  + +++         K +LE    + Q+L E+  L+ D  + I++    MEN + +L++     +
Sbjct:  154 IKDGDKLCKLCSLRLVMPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSEHQNRLSAVFIECPVCKQETPLGPKGIKALPCDYIVTNILDL--------SNLESE----HIVCTSCKS----KEEAISRCNDCANFLCNGCDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSENLKYYCFTCQVPTCNDCLLSDHKGSDHHYETATVAEQAVRADLEETLSDTLKKADYCNDAGSNLGSALTELQSQHDTVRQQIEDAYKCYKRMLE--SIKDQMLNELGRLHSDRELKIMDLMQSMENTMGKLQHAAQFGQ 466

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Fly
Match: mei-P26 (gene:FBgn0026206 transcript:FBtr0071303)

HSP 1 Score: 101.679 bits (252), Expect = 9.688e-22
Identity = 78/331 (23.56%), Postives = 143/331 (43.20%), Query Frame = 1

Query:  454 IQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYS--------DYRE---------FTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLF-----------DLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEH--SDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMAS------KLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAE 1338
            I+D   +CK+C      P+ LSCLH FC +CL+  +  +               D  E           CP+C++ T L   G++ LP +++V ++ ++        ++L SE    +  C  C+     K EA ++C DC+  LC  C   H+  +  + H +             L I   V C  H  E+++++C  CQ   C  C  ++H  SDH       A    ++D+E+ LS + +    C    S + +    ++S  + +++         K +LE    + Q+L E+  L+ D  + I++    MEN + +L++     +
Sbjct:  154 IKDGDKLCKLCSLRLVMPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSEHQNRLSAVFIECPVCKQETPLGPKGIKALPCDYIVTNILDL--------SNLESE----HIVCTSCKS----KEEAISRCNDCANFLCNGCDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSENLKYYCFTCQVPTCNDCLLSDHKGSDHHYETATVAEQAVRADLEETLSDTLKKADYCNDAGSNLGSALTELQSQHDTVRQQIEDAYKCYKRMLE--SIKDQMLNELGRLHSDRELKIMDLMQSMENTMGKLQHAAQFGQ 466

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Zebrafish
Match: trim2a (tripartite motif containing 2a [Source:ZFIN;Acc:ZDB-GENE-050327-99])

HSP 1 Score: 106.301 bits (264), Expect = 3.053e-23
Identity = 71/275 (25.82%), Postives = 118/275 (42.91%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRH----KESQLLEEIRNLYG 1254
            + ++I  + LIC ICL+ Y  PK L CLHTFC  CL+N+I         S     +CP+CR+ + LP  GV  L  NF + +L E++KK  +S                    L+    +A         L C N                             H    + F+C PC+  +C  CT  EH++H      + + ++K+ +++QL   +  + + E  L  ++ + Q + S ++ I+EM      E++     ++S LL E+   YG
Sbjct:   12 VVRQIDKQFLICSICLDRYNNPKVLPCLHTFCERCLQNYIP--------SHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMEVLKKSPNS-------------------NLSEDYTDAINGVATGQPLSCPN-----------------------------HGGNVMEFYCPPCETAMCEECTSGEHAEHATVPLKDVLEQHKASLQEQLDAVKNRLPEIESALEVLSEILQQLSSQKSSIEEMIHATFEELQKTLNVRKSVLLMELEVNYG 230

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Zebrafish
Match: trim24 (tripartite motif containing 24 [Source:ZFIN;Acc:ZDB-GENE-030131-5913])

HSP 1 Score: 98.9821 bits (245), Expect = 7.414e-21
Identity = 78/281 (27.76%), Postives = 122/281 (43.42%), Query Frame = 1

Query:  472 ICKICLENY--KQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSL----------FDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINN----VEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMI 1266
            +C +C  ++  ++PK L CLH+FC  CL  H     T           CP+C++        V  L DNF V          KDSV       ST    CQ+C   ++   EA   C++C + LC  C + H++ K T+ H++             + +  V C IH +E ++ FC+ C    C  C   +H DH      +A   +K  +E      QE     E   + INN    V++  K+  N+IK+    LI+EI  K   L+ ++  +  D+ I
Sbjct:   50 VCPVCKLSFSSREPKLLPCLHSFCKRCLPAHSSPAGTTSTAKQLSMIRCPVCQQECM----DVEVL-DNFFV----------KDSVE---VPSSTMEKSCQLCMSCDDNT-EASGFCVECVEFLCVTCIDAHQRVKFTRDHTVRQITEMSSEAMGASTQKPVFCDIHRQEPLKLFCETCDRLTCRDCQLLKHKDHNYQFLEDAYRNHKEHLENMTCQLQEKKKAIEDVTNTINNGLQQVDENRKTVANEIKKSICNLIMEINRKGKLLVNQLEAITKDHEI 311

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Zebrafish
Match: trim3a (tripartite motif containing 3a [Source:ZFIN;Acc:ZDB-GENE-080522-4])

HSP 1 Score: 95.5153 bits (236), Expect = 8.575e-20
Identity = 61/273 (22.34%), Postives = 119/273 (43.59%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTEN----QIKEMASKLILEIRHKESQLLEEIRNL 1248
            + ++I  + L+C ICLE+Y  PK L CLHTFC  CL+N+I  +            +CP+CR+ + LP  GV  L +NF + +L E++++ +D     T  E+++               E+         L C N                             H  + + F+C+ C+  +C+ CT  EH +H      + + ++K+ ++ QL   +  + Q    +  +N + + +   +N    +I     +L   +  +++ L+ ++ N+
Sbjct:   16 VVRQIDKQFLVCSICLEHYHNPKVLPCLHTFCERCLQNYIPPQSL--------TLSCPVCRQTSILPEKGVAALQNNFFITNLMEVLQREQD----CTRSEASSGL-------------ESAGAATYAPPLSCPN-----------------------------HEGKVMEFYCESCETAMCLECTEGEHREHVTVPLRDVLEQHKAALKNQLDAIRNRLPQLTAAIELVNEISKQLTDRKNEAVTEISNTFEELEKALHQRKTTLITDLENI 234

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Zebrafish
Match: ftr56 (finTRIM family, member 56 [Source:ZFIN;Acc:ZDB-GENE-030131-2801])

HSP 1 Score: 94.3597 bits (233), Expect = 1.040e-19
Identity = 77/267 (28.84%), Postives = 130/267 (48.69%), Query Frame = 1

Query:  463 ELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIE-NDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHE-ITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQII-KSTENQIKE---MASKLILEIRHKESQLLEEIRN 1245
            E   C +CLE  K P ++ C H++C  C+ ++   E       + R ++CP CR+ T  P   + K   N ++A + E +KK K     + + +         C     RK +A   C+ C    C+N  E H      ++H+L D      ++IC+ H ++ +  +C+  Q CIC+LC  +EH DHE ++   E   K K   E Q  F Q+I  + E KL ++N   +I  +S +  +K+   + S+LI  I  K S++ + IR+
Sbjct:    9 EQFSCPVCLELLKNPVAIPCGHSYCMSCITDYWHHE------DEKRVYSCPQCRQ-TFSPRPALNK---NTMLAEVVEQLKKTKHHTAAVPAGDGDVE-----CDSCTGRKHKAIKSCLVCLNSYCQNHLEQHENLFKGKRHNLIDATGRLQEMICRKH-DKLLEIYCRTDQRCICMLCMVDEHKDHETVSTSAERTEKQKQLGEIQRKFQQQIQKR-ERKLQELNEAVKIHERSAQTAVKDSERVFSELIRSIERKRSEVTQMIRD 258

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Zebrafish
Match: trim45 (tripartite motif containing 45 [Source:ZFIN;Acc:ZDB-GENE-070912-389])

HSP 1 Score: 89.7373 bits (221), Expect = 3.137e-18
Identity = 65/265 (24.53%), Postives = 111/265 (41.89%), Query Frame = 1

Query:  472 ICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYRE-----------FTCPLCRKRTTLPMGGVRKLP-DNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIR 1209
            +C +C   Y++PK L CLHTFCA+C+   ++     +   D R              CP C     LP  GV  L  D+  +  +F       +SV             C +C   +  KR     C  C   LC  C++ HR+ K T  HS+  L        +   ++C +HP + +R FC+PC   +C+ C    H +H  +  +E + +Y   I   L      +   + +L+++    + + +++  ++     L  EIR
Sbjct:   26 VCGVCNRMYREPKILPCLHTFCADCVRQ-LEPFSVRRVNGDRRSPGEDNSGSGSTILCPQCDSEVDLPPSGVDGLTTDHLALDEVFTETLVVNNSV------------LCDLCSDSDAGKR-----CEVCCVNLCDFCSQAHRRQKRTSSHSIQTLQELKSQGRLTRPILCSLHPGQELRLFCEPCDLTVCLECAATFHREHHCSSTHEVISRYGDRIRDLL------VRSLKPRLARLEESLRRVDTSQEAMQARTDTLAGEIR 266

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Xenopus
Match: actr6 (ARP6 actin related protein 6 homolog [Source:Xenbase;Acc:XB-GENE-5860964])

HSP 1 Score: 97.4413 bits (241), Expect = 2.716e-20
Identity = 69/282 (24.47%), Postives = 119/282 (42.20%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRH-----------KESQLLEEIRNLYG 1254
            + ++I  + LIC ICL+ YK PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L +NF + +L +++++  D+      EES+          L      A  K + C                                    H    + F+C+ C+  +C  CT  EH++H      + V ++K+ ++ QL   ++       +L +I++  Q +    NQ+    + ++ EI             ++S LL E+   YG
Sbjct:   12 VVRQIDKQFLICSICLDRYKNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVSALQNNFFITNLMDVLQRSPDNGI----EESSI---------LETVSAVAAGKPLSCPN----------------------------------HDGNVMEFYCQSCETAMCQDCTGGEHAEHPTVPLKDVVEQHKAALQAQLDAVKK-------RLPEIDSALQCVSEIVNQLASQKTSIVEEIHSTFDDLQKTLNVRKSVLLMELEVNYG 231

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Xenopus
Match: actr6 (ARP6 actin related protein 6 homolog [Source:Xenbase;Acc:XB-GENE-5860964])

HSP 1 Score: 97.0561 bits (240), Expect = 2.943e-20
Identity = 69/282 (24.47%), Postives = 119/282 (42.20%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRH-----------KESQLLEEIRNLYG 1254
            + ++I  + LIC ICL+ YK PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L +NF + +L +++++  D+      EES+          L      A  K + C                                    H    + F+C+ C+  +C  CT  EH++H      + V ++K+ ++ QL   ++       +L +I++  Q +    NQ+    + ++ EI             ++S LL E+   YG
Sbjct:   12 VVRQIDKQFLICSICLDRYKNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVSALQNNFFITNLMDVLQRSPDNGI----EESSI---------LETVSAVAAGKPLSCPN----------------------------------HDGNVMEFYCQSCETAMCQDCTGGEHAEHPTVPLKDVVEQHKAALQAQLDAVKK-------RLPEIDSALQCVSEIVNQLASQKTSIVEEIHSTFDDLQKTLNVRKSVLLMELEVNYG 231

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Xenopus
Match: actr6 (ARP6 actin related protein 6 homolog [Source:Xenbase;Acc:XB-GENE-5860964])

HSP 1 Score: 97.0561 bits (240), Expect = 3.303e-20
Identity = 69/282 (24.47%), Postives = 119/282 (42.20%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRH-----------KESQLLEEIRNLYG 1254
            + ++I  + LIC ICL+ YK PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L +NF + +L +++++  D+      EES+          L      A  K + C                                    H    + F+C+ C+  +C  CT  EH++H      + V ++K+ ++ QL   ++       +L +I++  Q +    NQ+    + ++ EI             ++S LL E+   YG
Sbjct:   25 VVRQIDKQFLICSICLDRYKNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVSALQNNFFITNLMDVLQRSPDNGI----EESSI---------LETVSAVAAGKPLSCPN----------------------------------HDGNVMEFYCQSCETAMCQDCTGGEHAEHPTVPLKDVVEQHKAALQAQLDAVKK-------RLPEIDSALQCVSEIVNQLASQKTSIVEEIHSTFDDLQKTLNVRKSVLLMELEVNYG 244

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Xenopus
Match: trim45 (tripartite motif containing 45 [Source:NCBI gene;Acc:496435])

HSP 1 Score: 93.2041 bits (230), Expect = 3.132e-19
Identity = 57/235 (24.26%), Postives = 95/235 (40.43%), Query Frame = 1

Query:  475 CKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFT--CPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLN-------IENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQII 1152
            C  C + + QP+ L CLHT C  CL          K +S    ++  CP+C     LP GGV +L  +++  +   + + +   +             C +CR+    KR     C +C   +C  C + HR+ K T  H L  L        +     C +HP E++  FC+PC    C  C    H  H++    E    ++  + + L  ++  I Q E  L  +    + +
Sbjct:   16 CPQCQQPFCQPRILPCLHTLCGGCLAKLEPFSALGKGHSAGTHWSVLCPVCDSEVALPAGGVEELLPDWLAEAEVLLAQVQSGGLA----------LPCDLCREGQAEKR-----CQECKVNVCEFCCQAHRRQKRTAAHPLHPLQDLSLGTILPPAPCCTLHPLEALGLFCEPCTVPCCRDCAIGHHRGHDLRPAAECAGGHRESLLRALQEAEPHIEQLEAALGGVQEAGKAL 235

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Xenopus
Match: TRIM33 (tripartite motif containing 33 [Source:NCBI gene;Acc:733764])

HSP 1 Score: 88.9669 bits (219), Expect = 1.541e-17
Identity = 80/302 (26.49%), Postives = 131/302 (43.38%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENY-KQPKSLSCLHTFCAECL---ENHIQGEVTYKKYSDYREFT---CPLCRKRTTLPMGGVRK--LPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLF---DLNIEN-------DVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINN----VEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIE 1278
            L   + D   +CK+ L++   +PK L CLH+FC  CL   E  +   +      D ++     CP+CR+         R+  L DN+ V    E+      S TD  SE        Q+C    +    A   C++C + LC+ C E H++ K T+ H +    D++ E+        V C +H +E ++ FC+ C    C  C   EH +H      EA    K  IE  L+   E  +      +++ N    V +  K  E +IK     LI EI  K   LL+++ ++  +  I +++
Sbjct:  214 LVVNLLDTCAVCKLSLQSRDSEPKLLPCLHSFCRRCLPEPERQLSVPLPGGTNGDIQQVGVIRCPVCRQE-------CRQIDLVDNYFVKDTSEV-----PSSTDEKSE--------QVCTSCEDNA-SAVGFCVECGEWLCKTCIEAHQRVKFTKDHIITKKEDVSSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLESVTKERQIKLVQ 494

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Mouse
Match: Trim56 (tripartite motif-containing 56 [Source:MGI Symbol;Acc:MGI:2685298])

HSP 1 Score: 125.946 bits (315), Expect = 2.053e-29
Identity = 80/290 (27.59%), Postives = 132/290 (45.52%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLEN-HIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKR--EAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL------------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQI------IKSTENQIKEMASKLILEIRHKESQLLEEIRNL 1248
            L + +  + L CKICLE    PK+L CLHT+C +CL    I G+V            CP CR+   +P  GV     NF V  L +++K R     D+ S + T    C +C  +  +     A  +C+DC+  LC+ C + HR ++ T +H + DL                   C  HP E++ F C+PC   +C  C    H DH      EAV   K  +E+ L+     +   E++ +++   E +        S   Q++E A +++  +  ++ ++L ++R L
Sbjct:   10 LLEALSSDFLACKICLEQLHTPKTLPCLHTYCQDCLAQLDIGGQV-----------RCPECREIVPVPAEGVAAFKTNFFVNGLLDLVKARAPG--DVHSGKPT----CALCPLVGGKSSGGPATARCLDCADDLCQACADGHRCSRQTHKHRVVDLVGYRAGWYDEEARERQASQCPQHPGEALCFLCQPCSQLLCKDCRLGPHIDHPCLPLAEAVRSRKPGLEELLAGVDSNL--VELEATRVAEKEALALLREQAASVGTQVEEAAERILKSLLAQKQEVLGQLRAL 280

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Mouse
Match: Trim56 (tripartite motif-containing 56 [Source:MGI Symbol;Acc:MGI:2685298])

HSP 1 Score: 108.227 bits (269), Expect = 3.059e-26
Identity = 68/217 (31.34%), Postives = 98/217 (45.16%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLEN-HIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKR--EAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL------------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAV 1047
            L + +  + L CKICLE    PK+L CLHT+C +CL    I G+V            CP CR+   +P  GV     NF V  L +++K R     D+ S + T    C +C  +  +     A  +C+DC+  LC+ C + HR ++ T +H + DL                   C  HP E++ F C+PC   +C  C    H DH      EAV
Sbjct:   10 LLEALSSDFLACKICLEQLHTPKTLPCLHTYCQDCLAQLDIGGQV-----------RCPECREIVPVPAEGVAAFKTNFFVNGLLDLVKARAPG--DVHSGKPT----CALCPLVGGKSSGGPATARCLDCADDLCQACADGHRCSRQTHKHRVVDLVGYRAGWYDEEARERQASQCPQHPGEALCFLCQPCSQLLCKDCRLGPHIDHPCLPLAEAV 209

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Mouse
Match: Trim45 (tripartite motif-containing 45 [Source:MGI Symbol;Acc:MGI:1918187])

HSP 1 Score: 102.064 bits (253), Expect = 7.069e-22
Identity = 79/349 (22.64%), Postives = 143/349 (40.97%), Query Frame = 1

Query:  400 HSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLEN-------HIQG--EVTYKKYSDYRE-----------FTCPLCRKRTTLPMGGVRKLPDNFVVAS--LFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKI----NNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVIL 1347
            H +Q+ N     GK           C  CL  +K P+ L CLHT C  CLE         I+G    T  + S +++             CP+C  +  LP+GGV+ L  + +  +  L E ++                   C +C       RE + +C  C   LC  C + HR+ K T  H++ DL        +   ++C  HP E +R FC+ C   +C  C   EH +H     +  + K+   + + L  +Q  +   E  L++I    N +++ +++    ++  +   I  I     +LL+++ ++       +   K+ +E  L++++      E +L
Sbjct:   13 HKLQDANASGSSGKTH---------CPTCLRLFKVPRLLPCLHTVCTTCLEKLDPFSVVDIRGGDSDTSSEGSVFQDPELCSLQPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVLLENLRGEGQ------------GLVCDLCSD-----REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSQVGKPILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLRDTQPHVEALEDALAQIKSVNNALQERVEAVAADVRTFSEGYIKAIEEHRDKLLQQLDDIRIQRETALQLQKAQLEQLLADMRTGVEFTEHLL 335

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Mouse
Match: Trim45 (tripartite motif-containing 45 [Source:MGI Symbol;Acc:MGI:1918187])

HSP 1 Score: 100.523 bits (249), Expect = 1.545e-21
Identity = 81/350 (23.14%), Postives = 145/350 (41.43%), Query Frame = 1

Query:  400 HSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLEN-------HIQG--EVTYKKYSDYRE-----------FTCPLCRKRTTLPMGGVRKLPDNFVVAS--LFEMIKKRKDS-VTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKI----NNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVIL 1347
            H +Q+ N     GK           C  CL  +K P+ L CLHT C  CLE         I+G    T  + S +++             CP+C  +  LP+GGV+ L  + +  +  L E ++      V DL S+                  RE + +C  C   LC  C + HR+ K T  H++ DL        +   ++C  HP E +R FC+ C   +C  C   EH +H     +  + K+   + + L  +Q  +   E  L++I    N +++ +++    ++  +   I  I     +LL+++ ++       +   K+ +E  L++++      E +L
Sbjct:   13 HKLQDANASGSSGKTH---------CPTCLRLFKVPRLLPCLHTVCTTCLEKLDPFSVVDIRGGDSDTSSEGSVFQDPELCSLQPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVLLENLRGEGQGLVCDLCSD------------------REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSQVGKPILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLRDTQPHVEALEDALAQIKSVNNALQERVEAVAADVRTFSEGYIKAIEEHRDKLLQQLDDIRIQRETALQLQKAQLEQLLADMRTGVEFTEHLL 335

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Mouse
Match: Trim45 (tripartite motif-containing 45 [Source:MGI Symbol;Acc:MGI:1918187])

HSP 1 Score: 100.523 bits (249), Expect = 1.545e-21
Identity = 81/350 (23.14%), Postives = 145/350 (41.43%), Query Frame = 1

Query:  400 HSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLEN-------HIQG--EVTYKKYSDYRE-----------FTCPLCRKRTTLPMGGVRKLPDNFVVAS--LFEMIKKRKDS-VTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKI----NNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVIL 1347
            H +Q+ N     GK           C  CL  +K P+ L CLHT C  CLE         I+G    T  + S +++             CP+C  +  LP+GGV+ L  + +  +  L E ++      V DL S+                  RE + +C  C   LC  C + HR+ K T  H++ DL        +   ++C  HP E +R FC+ C   +C  C   EH +H     +  + K+   + + L  +Q  +   E  L++I    N +++ +++    ++  +   I  I     +LL+++ ++       +   K+ +E  L++++      E +L
Sbjct:   13 HKLQDANASGSSGKTH---------CPTCLRLFKVPRLLPCLHTVCTTCLEKLDPFSVVDIRGGDSDTSSEGSVFQDPELCSLQPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVLLENLRGEGQGLVCDLCSD------------------REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSQVGKPILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLRDTQPHVEALEDALAQIKSVNNALQERVEAVAADVRTFSEGYIKAIEEHRDKLLQQLDDIRIQRETALQLQKAQLEQLLADMRTGVEFTEHLL 335

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BLAST of Tripartite motif-containing protein 2 vs. UniProt/SwissProt
Match: sp|E1BD59|TRI56_BOVIN (E3 ubiquitin-protein ligase TRIM56 OS=Bos taurus OX=9913 GN=TRIM56 PE=2 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 6.432e-31
Identity = 75/280 (26.79%), Postives = 124/280 (44.29%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKR--EAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL------------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEI 1239
            L + +  + L CKICLE  + PK+L CLHT+C +CL    +G              CP CR+   +P  GV     NF V  L +++K R     DL + +      C +C  +        A  +C+DC+  LC+ C + HR T+ T  H + DL                   C  HP E++RF C+PC   +C  C  + H DH      EAV   +  +E       E+++  +  L+++       K    +++E A+K++ ++     ++L  +
Sbjct:   10 LLEALSSDFLACKICLEQLRVPKTLPCLHTYCQDCLAQLAEGS----------RLRCPECRESVPVPPAGVAAFKTNFFVNGLLDLVKARAGG--DLRAGKPA----CALCPLMGGASAGGPATARCLDCADDLCQACADGHRCTRQTHSHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLE-------ELLAGVDNNLAELEATRLAEKEALARLREQAAKVVTQVEEASERVLRAL 266

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BLAST of Tripartite motif-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q9BRZ2|TRI56_HUMAN (E3 ubiquitin-protein ligase TRIM56 OS=Homo sapiens OX=9606 GN=TRIM56 PE=1 SV=3)

HSP 1 Score: 128.257 bits (321), Expect = 2.436e-29
Identity = 75/285 (26.32%), Postives = 127/285 (44.56%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNN--RKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL------------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQ----EIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIR 1242
            L + +  + L CKICLE  + PK+L CLHT+C +CL           + +D     CP CR+   +P  GV     NF V  L +++K R  +  DL + +      C +C  +        A  +C+DC+  LC+ C + HR T+ T  H + DL                   C  HP E++RF C+PC   +C  C  + H DH      EAV   +  +E  L+       E+ +   ++   +  + +       Q++E A  ++  +  ++ ++L ++R
Sbjct:   10 LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCL----------AQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKAR--ACGDLRAGKPA----CALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLR 278

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BLAST of Tripartite motif-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q80VI1|TRI56_MOUSE (E3 ubiquitin-protein ligase TRIM56 OS=Mus musculus OX=10090 GN=Trim56 PE=1 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 1.338e-28
Identity = 80/290 (27.59%), Postives = 132/290 (45.52%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLEN-HIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKR--EAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL------------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQI------IKSTENQIKEMASKLILEIRHKESQLLEEIRNL 1248
            L + +  + L CKICLE    PK+L CLHT+C +CL    I G+V            CP CR+   +P  GV     NF V  L +++K R     D+ S + T    C +C  +  +     A  +C+DC+  LC+ C + HR ++ T +H + DL                   C  HP E++ F C+PC   +C  C    H DH      EAV   K  +E+ L+     +   E++ +++   E +        S   Q++E A +++  +  ++ ++L ++R L
Sbjct:   10 LLEALSSDFLACKICLEQLHTPKTLPCLHTYCQDCLAQLDIGGQV-----------RCPECREIVPVPAEGVAAFKTNFFVNGLLDLVKARAPG--DVHSGKPT----CALCPLVGGKSSGGPATARCLDCADDLCQACADGHRCSRQTHKHRVVDLVGYRAGWYDEEARERQASQCPQHPGEALCFLCQPCSQLLCKDCRLGPHIDHPCLPLAEAVRSRKPGLEELLAGVDSNL--VELEATRVAEKEALALLREQAASVGTQVEEAAERILKSLLAQKQEVLGQLRAL 280

[Close]

BLAST of Tripartite motif-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q5BIM1|TRI45_BOVIN (Tripartite motif-containing protein 45 OS=Bos taurus OX=9913 GN=TRIM45 PE=2 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 3.381e-23
Identity = 78/322 (24.22%), Postives = 136/322 (42.24%), Query Frame = 1

Query:  475 CKICLENYKQPKSLSCLHTFCAECLEN-------HIQG--EVTYKKYSDYREFT-----------CPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINN----VEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVIL 1347
            C +C+  +K P+ L CLHT C  CLE         I+G    T  + S ++E             CP+C  +  LPMGGV+ L  + +  +   +   R +               C +C       RE + +C  C   LCR C + HR+ K T  H++ DL        I   ++C  HP E +R FC+ C   +C  C   EH +H     +  + K+   + + L  +Q  +   E  L++I      V++ +K+    I+  +   I  I     +LL+++ ++       +   K+ +E  L++++      E +L
Sbjct:   29 CPLCMGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGESDTSSEGSVFQELKPRALQPQIGILCPVCDAQVDLPMGGVKALTIDHLAMNDVMLESLRGEG----------QGLVCDLCSD-----REVEKRCQTCKANLCRFCCQAHRRQKKTTYHTMVDLKDLKGYSQIGKPILCPAHPAEELRLFCELCDRPVCRDCVVGEHREHPCDFTSNVIHKHGDSVRELLRGTQPHVEALEEALAQIKGTNSAVQERVKAVAADIRTFSEGYIKAIEEHRDKLLKQLEDIRVQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335

[Close]

BLAST of Tripartite motif-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q9H8W5|TRI45_HUMAN (Tripartite motif-containing protein 45 OS=Homo sapiens OX=9606 GN=TRIM45 PE=1 SV=2)

HSP 1 Score: 104.76 bits (260), Expect = 4.433e-22
Identity = 75/322 (23.29%), Postives = 137/322 (42.55%), Query Frame = 1

Query:  475 CKICLENYKQPKSLSCLHTFCAECLEN-------HIQG--EVTYKKYSDYREF-----------TCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKIN----NVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVIL 1347
            C +CL  +K P+ L CLHT C  CLE         I+G    T  + S ++E             CP+C  +  LPMGGV+ L  + +  +   +   R +               C +C       RE + +C  C   LC  C + HR+ K T  H++ DL        I   ++C +HP E +R FC+ C   +C  C   EH +H     +  + K+   + + L  +Q  +   E  L++I+     +++ +++    ++  +   I  I     +LL+++ ++       +   K+ +E  L++++      E +L
Sbjct:   29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEG----------QGLVCDLCND-----REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLL 335

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BLAST of Tripartite motif-containing protein 2 vs. TrEMBL
Match: A0A0L8HBK4 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22018098mg PE=4 SV=1)

HSP 1 Score: 395.586 bits (1015), Expect = 2.248e-126
Identity = 217/450 (48.22%), Postives = 291/450 (64.67%), Query Frame = 1

Query:  433 GGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNF-FCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDXXXXXXXXXXXXXXXXXXXXPENELPLSVMKEVKFIPGVFEFGCLQDMDRP-----MLTRPNFRIFNDYMSQEIP--KPDQKCVETQTDIE------------------ITKPNTASKSISTIPVQIANKAVNTRTRVIQ 1704
            G KLAQEI DE L CKICLE +K PK L CLHTFC +C+ENH+  E TYKKYSDYREFTCPLCRKRT LP+GGV+KLPDNF+V+SL E++ +++ S            F FC IC+ +N + REA +KC+DC+KLLC+ C E+H++TKVT+ HSLFD+ IE D+ CK H EE VRF+C+PCQACICVLCTFNEH DHEIT F++AVVKYK  I++ L   ++ I+  + ++  +   + +IK  E +I ++A   I EIR KE  L+EE+ +LYG  +++ I  K  M++ L  LKNTCN+ E++L+ KDIELLLL+ ++QEKL    ++   ELP +V K++ F PG  + G ++D DRP     M  R +     DY  ++ P   P      TQT+ E                     P    KSIST  V+   KAVNTR+R +Q
Sbjct:    8 GNKLAQEIHDEFLTCKICLEGFKNPKCLDCLHTFCEQCIENHVMSECTYKKYSDYREFTCPLCRKRTNLPIGGVKKLPDNFLVSSLGEVVARQRPS-----------KFPFCDICKMVNRKHREASSKCLDCNKLLCKPCVELHKETKVTKSHSLFDVEIEKDIECKEHKEEVVRFYCEPCQACICVLCTFNEHKDHEITNFSDAVVKYKDSIQRLLESCKDRINVYDTQIDTLGRCDTLIKDAEQKIHDVAIAFIAEIRSKEKTLVEELHSLYGSEVMEYINRKVEMQSNLESLKNTCNLTELVLKGKDIELLLLKNQVQEKLSCLSEIELKELPNTVCKQILFTPGSIDLGTIEDPDRPKPKVSMQPRRSLSA-ADYWREKSPTRAPPTSSTSTQTEKEDKSQKLREAAIQTEVEETPAPPGADDKSISTDKVETEEKAVNTRSRSLQ 445

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BLAST of Tripartite motif-containing protein 2 vs. TrEMBL
Match: A0A1S3IWQ5 (E3 ubiquitin-protein ligase TRIM56 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106168199 PE=4 SV=1)

HSP 1 Score: 393.275 bits (1009), Expect = 1.360e-124
Identity = 218/488 (44.67%), Postives = 308/488 (63.11%), Query Frame = 1

Query:  352 NLNDAEIFKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNF-FCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDXXXXXXXXXXXXXXXXXXXXPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRP--NFRIFNDYMSQEI----PKPDQKCVETQTDIEIT------------KPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLI 1758
             ++ ++I KS S  P        +    GKLAQEI +E L CKICLE YK+PKSL+CLHTFC  C+ENH   E +YKKYS+YR+FTCPLCRKRT LP GGV+ LPDNF+VASL E+I ++K            T F FC IC+ +  + REA +KC+DC+KLLC+ C E+HR+TKVT+ HS+FD+ IE DV CK HPEE VRF+C+PC+ C+CVLCTFNEH DH+I+ F++AV+ YK  I++ L+  ++ + + E +L  +   ++ +K  E +I++++ + I EIR +E QL+EE+ NLYG  +++ I  K+ M+  L  LK+TCN+ E+IL+ KDIELLLL+ ++QEKL     L    LP +V K+V+F+PG  + G +QDMDRP+        R F+   S E      +P+ +  +TQTD  IT            KPNT  K+ +T+P  +    + T        P   S    + + NLI
Sbjct:   36 GISPSDIEKSDSPEPTKEYTPILMANSAGKLAQEINEEFLTCKICLETYKEPKSLNCLHTFCESCIENHAMSESSYKKYSEYRDFTCPLCRKRTHLPTGGVKALPDNFLVASLTEVITRQK-----------PTKFPFCDICKLVAKKHREASSKCLDCAKLLCKQCVEVHRETKVTKNHSIFDVEIEKDVECKDHPEEVVRFYCEPCETCVCVLCTFNEHKDHDISNFSDAVMTYKDSIQKLLNGCKDKLDKHEQQLDTLAKADKSLKQAEQKIRDVSIQFISEIRTREKQLIEELHNLYGPALMEFIHRKADMQITLEGLKSTCNLTELILKGKDIELLLLKNQVQEKLRNLSDLDLKPLPPTVGKQVQFVPGALDMGYIQDMDRPLSMSKIRARRAFSSSSSTEYRDMQEQPEVRTTDTQTDSSITSASNCEKTTMTDKPNTNDKNCATVPPTVITVGLQTDV----PSPENTSANVVDVTVNLI 508

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BLAST of Tripartite motif-containing protein 2 vs. TrEMBL
Match: K1QSK1 (Tripartite motif-containing protein 56 OS=Crassostrea gigas OX=29159 GN=CGI_10008577 PE=4 SV=1)

HSP 1 Score: 392.504 bits (1007), Expect = 1.585e-124
Identity = 219/474 (46.20%), Postives = 306/474 (64.56%), Query Frame = 1

Query:  433 GGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNF-FCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDXXXXXXXXXXXXXXXXXXXXPENELPLSVMKEVKFIPGVFEFGCLQDMD-------------------RPMLTRPN--FRIFNDYMS--QEIPKPDQKCVETQTDI--EITKPNTASKSISTIPVQIANKAVNTRTRV------IQQKPRTNSVQF--TNGSSN 1752
            G KLAQEI DE L CKICLE YK PK L CLHTFC +C++NHI  E TYKKYSDYREFTCPLCRKRT LP+GGV+KLPDNF+V+SL E++++++ S            F FC IC+ +N + REA +KC+DC+KLLC+ C E+H++TKVT+ HS+FD+ IE D+ CK H EE VRF+C+PC+ACICVLCTFNEH DHEITQF+EAVVKYK +I   L   +E IS  + +L  ++  E +I++TE ++++ A + I +IR KE +L++++  +YG +++D +  ++ M+  +  LK+TC++ E++L+ KDIELLLL+K++QEKL    ++   ELP +V K + FIPG  + G L+D D                   R +   P   +R F+      +E  KP       QTD+    T   T  K++ T  V +  K VNTR+R       IQ  PR++S     TNG +N
Sbjct:   56 GNKLAQEINDEFLTCKICLEGYKSPKCLDCLHTFCEQCIDNHIMNECTYKKYSDYREFTCPLCRKRTQLPLGGVKKLPDNFLVSSLSELVQRQRPS-----------KFPFCDICKLVNRKHREATSKCLDCNKLLCKQCVEMHKETKVTKNHSIFDVEIEKDIECKEHSEEVVRFYCEPCEACICVLCTFNEHKDHEITQFSEAVVKYKENISCLLDDCKEKISTYDTQLEALSKCETVIRTTEQKVRDTAIQFIADIRTKEKKLIDDLHEIYGSDVMDYVSKRNDMQANVDSLKSTCSLTELVLRGKDIELLLLKKQVQEKLSGLSQIELRELPKTVEKSITFIPGGLDMGSLEDADSSQPGKIRTQRTFASIGSQRSVAAEPPKFYRTFSTQTEDVEEPGKPAFADTYVQTDVFGSGTNGETTDKAVETDKVDLQEKGVNTRSRSLQSVSGIQPIPRSSSRDDNNTNGETN 518

[Close]

BLAST of Tripartite motif-containing protein 2 vs. TrEMBL
Match: A0A1S3IYJ9 (E3 ubiquitin-protein ligase TRIM56 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106168199 PE=4 SV=1)

HSP 1 Score: 389.808 bits (1000), Expect = 6.146e-124
Identity = 213/461 (46.20%), Postives = 298/461 (64.64%), Query Frame = 1

Query:  433 GGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNF-FCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDXXXXXXXXXXXXXXXXXXXXPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRP--NFRIFNDYMSQEI----PKPDQKCVETQTDIEIT------------KPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLI 1758
             GKLAQEI +E L CKICLE YK+PKSL+CLHTFC  C+ENH   E +YKKYS+YR+FTCPLCRKRT LP GGV+ LPDNF+VASL E+I ++K            T F FC IC+ +  + REA +KC+DC+KLLC+ C E+HR+TKVT+ HS+FD+ IE DV CK HPEE VRF+C+PC+ C+CVLCTFNEH DH+I+ F++AV+ YK  I++ L+  ++ + + E +L  +   ++ +K  E +I++++ + I EIR +E QL+EE+ NLYG  +++ I  K+ M+  L  LK+TCN+ E+IL+ KDIELLLL+ ++QEKL     L    LP +V K+V+F+PG  + G +QDMDRP+        R F+   S E      +P+ +  +TQTD  IT            KPNT  K+ +T+P  +    + T        P   S    + + NLI
Sbjct:    5 AGKLAQEINEEFLTCKICLETYKEPKSLNCLHTFCESCIENHAMSESSYKKYSEYRDFTCPLCRKRTHLPTGGVKALPDNFLVASLTEVITRQK-----------PTKFPFCDICKLVAKKHREASSKCLDCAKLLCKQCVEVHRETKVTKNHSIFDVEIEKDVECKDHPEEVVRFYCEPCETCVCVLCTFNEHKDHDISNFSDAVMTYKDSIQKLLNGCKDKLDKHEQQLDTLAKADKSLKQAEQKIRDVSIQFISEIRTREKQLIEELHNLYGPALMEFIHRKADMQITLEGLKSTCNLTELILKGKDIELLLLKNQVQEKLRNLSDLDLKPLPPTVGKQVQFVPGALDMGYIQDMDRPLSMSKIRARRAFSSSSSTEYRDMQEQPEVRTTDTQTDSSITSASNCEKTTMTDKPNTNDKNCATVPPTVITVGLQTDV----PSPENTSANVVDVTVNLI 450

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BLAST of Tripartite motif-containing protein 2 vs. TrEMBL
Match: A0A1I8HGK2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 379.407 bits (973), Expect = 2.575e-120
Identity = 189/404 (46.78%), Postives = 279/404 (69.06%), Query Frame = 1

Query:  433 GGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKRE-AQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDXXXXXXXXXXXXXXXXXXXXPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFR------------IFNDYMSQEIPKPDQKCVETQTD 1605
             GKL QEI DE L+CKIC+  +K PK LSCLHTFC  C+ENHI  E  YKKYSDYREFTCPLCRKRT LP+GG +KLPDNF++++L + + +++ S         T++  C IC+ +  R +E A +KC+DC+KLLCR C E H++TKVT+ H++FD+  E D+ICK HP+E VRF+C+PCQAC+C++C FNEH +HE++ F+EAVVKYK+DIE  L+  +  I   E  + ++N+ E+ I   E +I+E+A + + +IR++E QL++E+ NLYG   +++I  K+ +++ L  LK+TC + E++LQ KDIELLLL++E+Q+KL       + +LP ++ KE++F+PG  E G +QDMD+P  ++  FR               D + QE  +P+ +  ETQT+
Sbjct:   59 AGKLVQEIHDEFLVCKICMSPFKTPKCLSCLHTFCEVCIENHIASEAAYKKYSDYREFTCPLCRKRTQLPVGGAKKLPDNFLISNLSDTMDRQQKS--------GTSSASCDICKMVGRRAKEQASSKCLDCNKLLCRACVEQHKETKVTRDHAIFDVETEKDIICKDHPDEVVRFYCEPCQACVCIICAFNEHKEHEVSNFSEAVVKYKADIEAVLADCKSKIGVYEKYMERVNSTERQITEAEKKIRELAIEFVADIRNREKQLIDEVHNLYGKQTMEVIGRKAELQSALETLKSTCALTEIVLQGKDIELLLLKREVQDKLSSLSMAMQIDLPKTMSKEIRFLPGHIELGSIQDMDKPNASK--FRSCIISNSSFSSLNSIDTVGQE-EQPELQSTETQTE 451

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Cavefish
Match: trim2a (tripartite motif containing 2 [Source:NCBI gene;Acc:103036279])

HSP 1 Score: 101.293 bits (251), Expect = 9.455e-22
Identity = 73/313 (23.32%), Postives = 132/313 (42.17%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSEL-------KNTCNMAEVIL 1347
            + ++I  + LIC ICL+ Y  PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L E++K+  DS                                               R  + T   S+  +     + C  H    + F+C PC+  +C  CT  EH++H      + + ++K+ +++QL   ++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG         + V++ QL+ L       +++C+  E  L
Sbjct:   12 VVRQIDKQFLICSICLDRYDNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMEVLKRGPDS----------------------------------------------GRGDERTGLDSIESVATGQPLSCPNHGGNVMEFYCPPCETAMCEECTSGEHAEHATVPLKDVLEQHKASLQEQLDAVKQRLPEIDSALQVLSEILQQLTNQKSLIEDDIHATFDELQKTLNVRKSVLLMELEVNYG-------LKQKVLQTQLASLLQGQDGMRSSCSFTEQAL 263

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Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSEL-------KNTCNMAEVIL 1347
            + ++I  + LIC ICL+ Y  PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L E++K+  DS                                               R  + T   S+  +     + C  H    + F+C PC+  +C  CT  EH++H      + + ++K+ +++QL   ++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG         + V++ QL+ L       +++C+  E  L
Sbjct:   12 VVRQIDKQFLICSICLDRYDNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMEVLKRGPDS----------------------------------------------GRGDERTGLDSIESVATGQPLSCPNHGGNVMEFYCPPCETAMCEECTSGEHAEHATVPLKDVLEQHKASLQEQLDAVKQRLPEIDSALQVLSEILQQLTNQKSLIEDDIHATFDELQKTLNVRKSVLLMELEVNYG-------LKQKVLQTQLASLLQGQDGMRSSCSFTEQAL 263

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Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSEL-------KNTCNMAEVIL 1347
            + ++I  + LIC ICL+ Y  PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L E++K+  DS                                               R  + T   S+  +     + C  H    + F+C PC+  +C  CT  EH++H      + + ++K+ +++QL   ++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG         + V++ QL+ L       +++C+  E  L
Sbjct:   12 VVRQIDKQFLICSICLDRYDNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMEVLKRGPDS----------------------------------------------GRGDERTGLDSIESVATGQPLSCPNHGGNVMEFYCPPCETAMCEECTSGEHAEHATVPLKDVLEQHKASLQEQLDAVKQRLPEIDSALQVLSEILQQLTNQKSLIEDDIHATFDELQKTLNVRKSVLLMELEVNYG-------LKQKVLQTQLASLLQGQDGMRSSCSFTEQAL 263

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Cavefish
Match: trim2a (tripartite motif containing 2 [Source:NCBI gene;Acc:103036279])

HSP 1 Score: 101.293 bits (251), Expect = 1.012e-21
Identity = 73/313 (23.32%), Postives = 132/313 (42.17%), Query Frame = 1

Query:  442 LAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSEL-------KNTCNMAEVIL 1347
            + ++I  + LIC ICL+ Y  PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L E++K+  DS                                               R  + T   S+  +     + C  H    + F+C PC+  +C  CT  EH++H      + + ++K+ +++QL   ++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG         + V++ QL+ L       +++C+  E  L
Sbjct:   12 VVRQIDKQFLICSICLDRYDNPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMEVLKRGPDS----------------------------------------------GRGDERTGLDSIESVATGQPLSCPNHGGNVMEFYCPPCETAMCEECTSGEHAEHATVPLKDVLEQHKASLQEQLDAVKQRLPEIDSALQVLSEILQQLTNQKSLIEDDIHATFDELQKTLNVRKSVLLMELEVNYG-------LKQKVLQTQLASLLQGQDGMRSSCSFTEQAL 263

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Cavefish
Match: trim45 (tripartite motif-containing protein 45-like [Source:NCBI gene;Acc:111189320])

HSP 1 Score: 97.0561 bits (240), Expect = 1.259e-20
Identity = 72/303 (23.76%), Postives = 128/303 (42.24%), Query Frame = 1

Query:  388 KSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECL--------------------ENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVAS--LFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDL-------NIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIR 1209
            + P   + N  ++   G  A +++    +C++C   +++PK L CLHTFCA+C+                    E   +G+V            CP C     LP  GV  L  + +     L E +   +  + DL SE S     C++C             C++    LC  C++ HR+ K T  HS+  L        +   V+C +HP + +R FC+PC   +C+ C    H DH+ +  ++ + ++   I + +S S         +LS++    + ++ ++  +K     L  EIR
Sbjct:   14 REPGAGLSNSAVRE-NGSAAGDVRSSRAVCRVCSRLFREPKLLPCLHTFCADCIRQLETFSAPGAGGGRSRAGAEGPARGQVPLT-------VLCPECDSEVDLPSSGVDGLTTDHLALDEVLMETLLMERSVLCDLCSE-SDAGKRCEVC-------------CLN----LCDFCSQAHRRQKRTSSHSIHSLEDLKSQGRLSRPVLCSLHPGQELRLFCEPCDLAVCLECAAVFHRDHQCSPTHDVINQHGDCIRELVSGSL------RPRLSRLEEAMRRVEISKEALKIRTDSLASEIR 284

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010730.1 (pep scaffold:Pmarinus_7.0:GL485872:9458:10706:1 gene:ENSPMAG00000009719.1 transcript:ENSPMAT00000010730.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 1.506e-12
Identity = 34/89 (38.20%), Postives = 47/89 (52.81%), Query Frame = 1

Query:  460 DELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYR-EFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSV 723
            +E L C +C   ++ P+ L C HTFC  CLE+ +QG +    +   R  F CP CR    LP+ G   LP NF   SL  ++ K + SV
Sbjct:    5 EEELTCPVCYSLFEDPRVLPCSHTFCRGCLEDILQGSLHLSPWRPLRTPFKCPSCRHVCELPLTGFTSLPVNF---SLRNIVDKYRTSV 90

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005270.1 (pep scaffold:Pmarinus_7.0:GL480405:17764:25842:-1 gene:ENSPMAG00000004750.1 transcript:ENSPMAT00000005270.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 9.015e-10
Identity = 55/228 (24.12%), Postives = 91/228 (39.91%), Query Frame = 1

Query:  475 CKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCR----KRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEE---STTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKV-TQQHSLFDLNIENDV-ICKIHPEESVRFFCKPCQACICVLCTFNEH-SDHEITQFNEAVVKYKSDIE---QQLSFSQEIISQCEIK 1119
            C +CL+ +  P +L C H+FC  C+E H      ++         CP CR    KR  L        P   ++A L +    R        S +   S+      +C      +  A   C+ C    C     +H +T   T+QH L +L     + +C  H    + FFC+   AC+C  C  +     H + +   AV   + D++   Q+L   Q  +S+ +I+
Sbjct:   14 CSVCLDMFITPCTLPCGHSFCRSCIETH------WRVNCARGGCDCPQCRHVFHKRPALQT----STPLASIIAQLGQRCPFRAADALAFISADPARSSPPALSSLCGLCTMSRVPAAKACLTCEVSFCGEHLRMHDETAAFTRQHRLLELPAAVALGVCGRH-GRPLEFFCRSDLACVCAACVNDGLCQGHAVEELQLAVGGAQMDLKQKRQKLKIKQMTVSKSKIE 230

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Sea Lamprey
Match: trim59 (tripartite motif containing 59 [Source:ZFIN;Acc:ZDB-GENE-060724-2])

HSP 1 Score: 57.3806 bits (137), Expect = 3.842e-9
Identity = 27/89 (30.34%), Postives = 49/89 (55.06%), Query Frame = 1

Query:  460 DELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYRE----FTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRK 714
            +E L C +C   +++P+ L C HTFC  CLE+ +Q   T +++  +R       CP CR    +P  G+  LP N+ + ++ E  ++++
Sbjct:    5 EEDLTCPVCFSLFEEPRVLPCSHTFCRRCLESVLQA--TVEQFPLWRALRVPLKCPSCRHMFDMPSAGLSYLPLNYSLVAIVEKYRRQQ 91

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004722.1 (pep scaffold:Pmarinus_7.0:GL477448:190469:194693:-1 gene:ENSPMAG00000004305.1 transcript:ENSPMAT00000004722.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 1.109e-7
Identity = 24/84 (28.57%), Postives = 40/84 (47.62%), Query Frame = 1

Query:  799 EAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIEND----------VICKIHPEESVRFFCKPCQACICVLCTFNEHSDH 1020
            +A+  C++C + LCR C E H++ K T+ H++   +   D          V C +H  E ++ FC+ C    C  C    H +H
Sbjct:   48 DAEGFCVECLEWLCRTCIEAHQRVKFTKDHAIRRKDDAQDDAAGMATLRPVYCPVHRREPLKLFCETCDRLTCRDCQLLGHKEH 131

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000299.1 (pep scaffold:Pmarinus_7.0:GL484837:4300:10751:-1 gene:ENSPMAG00000000266.1 transcript:ENSPMAT00000000299.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.447 bits (119), Expect = 1.194e-6
Identity = 60/252 (23.81%), Postives = 100/252 (39.68%), Query Frame = 1

Query:  469 LICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCR------KRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSV------------------TDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPE--ESVRFFCKPCQACIC-VLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVE 1143
            L C IC + Y+ P  L+C H+FC EC+           K  ++    CP CR       R  +     RKL  NF +A++ E     K S                     L  ++ + N    +C      KR+A   C  C+  +C+   E H    VT +H +  +     V  ++ PE  E ++ +C    AC+C V C   +H  HE+   +E     K       +    +     +K++K++++E
Sbjct:    8 LTCPICFQYYRDPVILNCKHSFCRECI----------LKTWEHGPSNCPHCRMLFFFMDRQEME----RKLEKNFQLANIVESFASLKLSTPAPKPAPKKKKSSKSVASVVLVPKDVSVNNTPIMCDWCVGAKRQAVKTCQLCAVSMCQEHLEPHL-VNVTFRHHIL-VKPCKPVKHRLCPEHREPLKMYCTQDNACVCTVCCIAGKHRGHELMPIDEFATSKKK------TMYLNVYGNVSLKVNKLSHLE 237

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Nematostella
Match: EDO47715 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLM1])

HSP 1 Score: 122.479 bits (306), Expect = 6.063e-29
Identity = 70/282 (24.82%), Postives = 134/282 (47.52%), Query Frame = 1

Query:  451 EIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLN-----------IENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKE----MASKLILEIRHKESQLLEEIRNLY 1251
            ++ + LL C ICLE Y+ PK L CLHTFC  CL+  IQ        S      CP CR    +P  GV  L  NF + ++ + +           +  ++   FC  C   N     A ++CI+C + LC  C   H++TK+T++H +  LN           +   ++C +H  E +++FC+ C   +C  C   +H +H      +   K++S++   +  +++ +++ +  + K+ +  + +     +I++       + I  I+ +E +LL ++ N++
Sbjct:    8 KLSEHLLKCPICLETYRTPKVLPCLHTFCQHCLKGMIQ--------SGENIIVCPTCRCEVCVPKEGVSALSTNFFINNMLDFLS---------VALSNSKPIFCTNCEDRNT----ASSRCIECMEFLCEQCVAAHKRTKLTKEHEILALNELQGQPEVQDKLHRPLVCSVHDNEVLKYFCETCDEPVCRECLIIDHREHRYGYLKDVDKKHRSEVGVLVMSTKKKLARLKEAIDKVTDTRKRLDCKAEEIRQEVMRHTQRCIEVIQEREQELLTQVNNIH 268

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Nematostella
Match: EDO34308 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPQ3])

HSP 1 Score: 119.013 bits (297), Expect = 7.807e-28
Identity = 78/319 (24.45%), Postives = 148/319 (46.39%), Query Frame = 1

Query:  439 KLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFD-----------LNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIK----STENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQ 1350
            ++ ++I D+L +C ICL+   +P+ L C+HTFC  C++     + +          TCP CRK T +P  GV  L  NF V  + ++++ + D +     E       C+ C   N     A ++C+DC+K LC  C   H++   T  H +             L+  +   CK H    +++FC  C   IC +CT  EH +H+     EA+   ++DI+  L  ++  I   +  L K++ + + +K    +   +I +     +  +   E++LL+++  ++      +   K  +E +L +L   C+ A+ + +
Sbjct:    6 EVLEQINDQL-VCAICLDRLVEPRLLICMHTFCTPCIQRISNNDASAS-------LTCPTCRKETPIPETGVESLHLNFFVNQMLDVVRHKADELKKEIRETRR----CEGCEN-NEEADVATSRCVDCNKPLCTTCVADHKRVHATLDHRVIAISEGEEGEDQALDKYSLTFCKYHTRNVIKYFCITCDEAICRVCTILEHREHQYVYPKEALPLRRNDIQGLLEKAKSRIPLLKGTLKKVDAMSRRLKDCHQALAKEIHQNTQARVKALIEGENELLKQLAGVHLAKQKVLGLQKDSIELELGKLTGCCDFADNVFK 311

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Nematostella
Match: EDO47716 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLM3])

HSP 1 Score: 110.153 bits (274), Expect = 5.710e-27
Identity = 64/254 (25.20%), Postives = 120/254 (47.24%), Query Frame = 1

Query:  451 EIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLN-----------IENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKE 1179
            ++ + LL C ICLE Y+ PK L CLHTFC  CL+  IQ        S      CP CR    +P  GV  L  NF + ++ + +           +  ++   FC  C   N     A ++CI+C + LC  C   H++TK+T++H +  LN           +   ++C +H  E +++FC+ C   +C  C   +H +H      +   K++S++   +  +++ +++ +  + K+ +  + +     +I++
Sbjct:    8 KLSEHLLKCPICLETYRTPKVLPCLHTFCQHCLKGMIQ--------SGENIIVCPTCRCEVCVPKEGVSALSTNFFINNMLDFLS---------VALSNSKPIFCTNCEDRNT----ASSRCIECMEFLCEQCVAAHKRTKLTKEHEILALNELQGQPEVQDKLHRPLVCSVHDNEVLKYFCETCDEPVCRECLIIDHREHRYGYLKDVDKKHRSEVGVLVMSTKKKLARLKEAIDKVTDTRKRLDCKAEEIRQ 240

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BLAST of Tripartite motif-containing protein 2 vs. Ensembl Nematostella
Match: EDO49584 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGQ9])

HSP 1 Score: 105.916 bits (263), Expect = 1.199e-23
Identity = 72/314 (22.93%), Postives = 131/314 (41.72%), Query Frame = 1

Query:  469 LICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLN-----------IENDVICKIHPEESVRFFCKPCQACICVLCTFNEHS--DHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNV----EQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKD 1359
            L C +C E +  P+ L CLHTFC  CLEN +               +CP CR    L   G+     NFVV ++ ++   R                 C  C +    K  A  +CI+C   LC +C   H + ++T+ H +  +            +   + C  H  E +R+FC+ C   IC  CT   HS  +H+ TQ  + + K  + I+  +   +  I   E     +  V    E   +  ++++++   +++  ++ +E  ++ E+ ++       +   +  +EN+L  L  TC   E +L+  +
Sbjct:   69 LFCPLCHEMFANPRLLPCLHTFCKRCLENLVP--------PRSHTLSCPSCRLDVALGERGINGFAPNFVVTTMIDVAAVRN---------HDQKPILCSSCEE----KLPAAARCIECMDFLCYDCRNAHMRLRLTKTHRVVSIEELRSSSHPEDLLHRPIFCSDHGHEKLRYFCESCDQAICRECTMTTHSTANHKYTQLTDTIDKQTNSIQTLVEKLRRKIPAVEQSTKDVEEVTCRLEARAEVAKSEVQKCFPRILKILQDREKSMMNEVESVVRQKSNVLSMQQERLENELKRLSITCTFTEQVLRHGN 361

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Nematostella
Match: EDO30616 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0A2])

HSP 1 Score: 98.5969 bits (244), Expect = 1.629e-22
Identity = 65/250 (26.00%), Postives = 117/250 (46.80%), Query Frame = 1

Query:  445 AQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYR-EFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLN---------IENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTE 1164
            ++ ++DE+  C +C+E++  P+ L CLH+FC  CLE           +S+ R +  CPLC+    +    V  L  NF++ S+  ++         LTSE+S     CQ+C    +    AQ +C +C   +C  C   H++ +  Q H++  L+         +     C  H  E ++ FC+ C+  IC  CT  +H +H+    ++ + + K          +EI+ + +   SKI ++EQ +   E
Sbjct:    6 SRRLEDEV-TCSLCIEHFNDPRVLPCLHSFCRHCLEE-------LAVHSEGRGKLVCPLCKAEFQISPADVSSLKVNFMINSIISVLPL-------LTSEDSKKKTVCQMC----DSGDPAQGRCNECDHFVCEQCISAHKRFRPLQHHTILSLDEIKSGKLLAMSKASFCTKHEGEVLKLFCESCKEVICRDCTVVDHKNHDYLFTSDVIAREK----------EEILERAKKVTSKITDIEQAMALVE 226

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Medaka
Match: trim2a (tripartite motif containing 2 [Source:NCBI gene;Acc:101163547])

HSP 1 Score: 104.76 bits (260), Expect = 7.725e-23
Identity = 72/282 (25.53%), Postives = 125/282 (44.33%), Query Frame = 1

Query:  421 IQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYG 1254
            I +I   + ++I  + LIC ICL+ Y+ PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L +++++  D+     S+E T          LNN        C+   +LL                             C  H    + F+C PC+  +C  CT  EH +H      + V ++K+ ++ QL  +++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG
Sbjct:    5 ISSIPSPVFRQIDKQFLICSICLDRYENPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMDVLQRAPDNC----SQEDTI---------LNN------IACVATGQLLS----------------------------CPNHGGSVMEFYCPPCETAMCQECTSGEHGEHPTVPLRDVVEQHKASLQDQLDVAKKRLPEIDSALHMLSEILQQLTNQKSLIEDDIHTTFDELQKTLNVRKSVLLMELEVNYG 231

[Close]

Query:  421 IQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYG 1254
            I +I   + ++I  + LIC ICL+ Y+ PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L +++++  D+     S+E T          LNN        C+   +LL                             C  H    + F+C PC+  +C  CT  EH +H      + V ++K+ ++ QL  +++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG
Sbjct:    5 ISSIPSPVFRQIDKQFLICSICLDRYENPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMDVLQRAPDNC----SQEDTI---------LNN------IACVATGQLLS----------------------------CPNHGGSVMEFYCPPCETAMCQECTSGEHGEHPTVPLRDVVEQHKASLQDQLDVAKKRLPEIDSALHMLSEILQQLTNQKSLIEDDIHTTFDELQKTLNVRKSVLLMELEVNYG 231

[Close]

Query:  421 IQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYG 1254
            I +I   + ++I  + LIC ICL+ Y+ PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L +++++  D+     S+E T          LNN        C+   +LL                             C  H    + F+C PC+  +C  CT  EH +H      + V ++K+ ++ QL  +++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG
Sbjct:    5 ISSIPSPVFRQIDKQFLICSICLDRYENPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMDVLQRAPDNC----SQEDTI---------LNN------IACVATGQLLS----------------------------CPNHGGSVMEFYCPPCETAMCQECTSGEHGEHPTVPLRDVVEQHKASLQDQLDVAKKRLPEIDSALHMLSEILQQLTNQKSLIEDDIHTTFDELQKTLNVRKSVLLMELEVNYG 231

[Close]

Query:  421 IQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKS----TENQIKEMASKLILEIRHKESQLLEEIRNLYG 1254
            I +I   + ++I  + LIC ICL+ Y+ PK L CLHTFC  CL+N+I         +     +CP+CR+ + LP  GV  L  NF + +L +++++  D+     S+E T          LNN        C+   +LL                             C  H    + F+C PC+  +C  CT  EH +H      + V ++K+ ++ QL  +++ + + +  L  ++ + Q + +     E+ I     +L   +  ++S LL E+   YG
Sbjct:    5 ISSIPSPVFRQIDKQFLICSICLDRYENPKVLPCLHTFCERCLQNYIP--------AHSLTLSCPVCRQTSILPEKGVAALQSNFFITNLMDVLQRAPDNC----SQEDTI---------LNN------IACVATGQLLS----------------------------CPNHGGSVMEFYCPPCETAMCQECTSGEHGEHPTVPLRDVVEQHKASLQDQLDVAKKRLPEIDSALHMLSEILQQLTNQKSLIEDDIHTTFDELQKTLNVRKSVLLMELEVNYG 231

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Medaka
Match: ENSORLT00000003321.2 (tripartite motif-containing protein 16-like [Source:NCBI gene;Acc:101166829])

HSP 1 Score: 96.2857 bits (238), Expect = 2.478e-20
Identity = 80/313 (25.56%), Postives = 154/313 (49.20%), Query Frame = 1

Query:  421 IQAIGGKLAQE---IQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTL-PMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSE---ESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFD--LNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINN-VEQIIKSTENQI---KEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKN 1320
            ++    ++AQ    +  E L C ICL+  K+P ++ C H++C +C++ H   +     +S      CP CRK   L P+     L  N ++A L E +KK     T+L S+       +  C +C   + RK +A   C+DC    C    + H      Q+H L D   N++ + IC +H +E ++ +C+  Q  IC LC  +EH  HE        ++ +  +++     Q+ I  CE  + K+   VE I  + +  +   +E+ S++I  ++++ S++ ++IR+   D +  +++ +  +E ++ +LK+
Sbjct:    9 VRCFRAEMAQRGLLLDQENLSCSICLDVLKEPVTVPCGHSYCMDCIKTHWDEDDQRGNHS------CPQCRKTFFLRPV-----LEKNIMLAELVEELKK-----TELRSDLCYAGPEDVSCDVC---SGRKMKAVKSCLDCLASYCEEHLQPHSVAPALQKHKLVDPSRNLQQN-ICSLH-DEVMKIYCRTDQQNICYLCLMDEHKGHETVSAATERMEKQKKLQETRQQIQQKIQDCEQAVKKLQQEVEDINTAADKSVEDSEEIFSEMIRLLQNRSSEVKQQIRSQQDDEVNRVLDLQEKLEQEIRDLKS 300

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Planmine SMEST
Match: SMESG000023375.1 (SMESG000023375.1)

HSP 1 Score: 1124 bits (2906), Expect = 0.000e+0
Identity = 584/586 (99.66%), Postives = 585/586 (99.83%), Query Frame = 1

Query:  211 RIYRRRFGKPSGMLLSYNSNEKKHERPMSWIPTSDFLKTFNGDTLGSNLNDAEIFKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDXXXXXXXXXXXXXXXXXXXXPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFRIFNDYMSQEIPKPDQKCVETQTDIEITKPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLIEIQPITSNEGKIMFVNSDKXXXXXXXXXXXXQAEKSKSNDTKDLIITASEILNDFIAQVNLETEDAAKLD 1968
            RIYRRRFGKPSGMLLSYNSNEKKHERPMSWIPTSDFLKTFNGDTLGSNLNDAE FKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTS+ESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDIELLLLQKEIQEKLLESQKLPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFRIFNDYMSQEIPKPDQKCVETQTDIEITKPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLIEIQPITSNEGKIMFVNSDKLLLSPSTRRRLSQAEKSKSNDTKDLIITASEILNDFIAQVNLETEDAAKLD
Sbjct:    8 RIYRRRFGKPSGMLLSYNSNEKKHERPMSWIPTSDFLKTFNGDTLGSNLNDAENFKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSDESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDIELLLLQKEIQEKLLESQKLPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFRIFNDYMSQEIPKPDQKCVETQTDIEITKPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLIEIQPITSNEGKIMFVNSDKLLLSPSTRRRLSQAEKSKSNDTKDLIITASEILNDFIAQVNLETEDAAKLD 593

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Planmine SMEST
Match: SMESG000023375.1 (SMESG000023375.1)

HSP 1 Score: 1030.01 bits (2662), Expect = 0.000e+0
Identity = 542/544 (99.63%), Postives = 543/544 (99.82%), Query Frame = 1

Query:  337 DTLGSNLNDAEIFKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDXXXXXXXXXXXXXXXXXXXXPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFRIFNDYMSQEIPKPDQKCVETQTDIEITKPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLIEIQPITSNEGKIMFVNSDKXXXXXXXXXXXXQAEKSKSNDTKDLIITASEILNDFIAQVNLETEDAAKLD 1968
            DTLGSNLNDAE FKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTS+ESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDIELLLLQKEIQEKLLESQKLPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFRIFNDYMSQEIPKPDQKCVETQTDIEITKPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLIEIQPITSNEGKIMFVNSDKLLLSPSTRRRLSQAEKSKSNDTKDLIITASEILNDFIAQVNLETEDAAKLD
Sbjct:   15 DTLGSNLNDAENFKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSDESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEIRNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDIELLLLQKEIQEKLLESQKLPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFRIFNDYMSQEIPKPDQKCVETQTDIEITKPNTASKSISTIPVQIANKAVNTRTRVIQQKPRTNSVQFTNGSSNLIEIQPITSNEGKIMFVNSDKLLLSPSTRRRLSQAEKSKSNDTKDLIITASEILNDFIAQVNLETEDAAKLD 558

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Planmine SMEST
Match: SMESG000035122.1 (SMESG000035122.1)

HSP 1 Score: 62.003 bits (149), Expect = 1.284e-9
Identity = 59/237 (24.89%), Postives = 94/237 (39.66%), Query Frame = 1

Query:  472 ICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHS----------------LFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKIN 1134
            +C+IC     +P  L CLH F   C+   I+ ++      DY +  CP C   T L        P N    +LF +   + DS     SE++ T   C +C            KC DC+ ++C  C  +H++  + Q H+                +  L+    V C IH E  +  FC  C   +C  C   +H +HEI    E       D++  +       ++C+I   K+N
Sbjct:   21 LCEICENRLSEPILLPCLHVFDKNCILG-IENDLL-----DYSQIKCPKCDFTTVLS----NSQPLN---VNLFNV---KLDSKHKDESEDNETK--CILC----TNDEIGVYKCSDCAGIICERCRILHKEVVIFQSHNNVQELTQKDRDNIKDVVKSLSDNKPVKCPIHKESHIDSFCFKCCTGLCTKCKIIDHKNHEIIPLEEIFESINKDLDSSM-------AKCKITKDKLN 228

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Planmine SMEST
Match: SMESG000035122.1 (SMESG000035122.1)

HSP 1 Score: 62.003 bits (149), Expect = 1.403e-9
Identity = 59/237 (24.89%), Postives = 94/237 (39.66%), Query Frame = 1

Query:  472 ICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHS----------------LFDLNIENDVICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKIN 1134
            +C+IC     +P  L CLH F   C+   I+ ++      DY +  CP C   T L        P N    +LF +   + DS     SE++ T   C +C            KC DC+ ++C  C  +H++  + Q H+                +  L+    V C IH E  +  FC  C   +C  C   +H +HEI    E       D++  +       ++C+I   K+N
Sbjct:   27 LCEICENRLSEPILLPCLHVFDKNCILG-IENDLL-----DYSQIKCPKCDFTTVLS----NSQPLN---VNLFNV---KLDSKHKDESEDNETK--CILC----TNDEIGVYKCSDCAGIICERCRILHKEVVIFQSHNNVQELTQKDRDNIKDVVKSLSDNKPVKCPIHKESHIDSFCFKCCTGLCTKCKIIDHKNHEIIPLEEIFESINKDLDSSM-------AKCKITKDKLN 234

[Close]

BLAST of Tripartite motif-containing protein 2 vs. Planmine SMEST
Match: SMESG000059098.1 (SMESG000059098.1)

HSP 1 Score: 60.077 bits (144), Expect = 5.476e-9
Identity = 65/297 (21.89%), Postives = 124/297 (41.75%), Query Frame = 1

Query:  427 AIGGKLAQEIQDELLICKICLENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTLPMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNNRKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQH--------------SLFDLNIEND--VICKIHPEESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFSQEIISQCEIKLSKINNVEQIIKSTENQ----IKEMASKLILEIRHKESQLLEEIRNLYGD 1257
            A GG L  + Q+   IC  C  ++ +P  L+CLH F   CL    + E T    S +   TCP C  ++   +  ++     + + S     K+   S  D        +F C +C        +++ KC+DC+ LLC  C  +H++ K    H               L   ++ ++  V C++H E     +C  C    C  C  ++H+DH      +   K +  I   +    +     +I + K+NN    + ++ ++    I+E+ ++    I   +++ L++ + L+ D
Sbjct:   17 AEGGSLENK-QELPTICSQCKNSFSEPVVLNCLHIFDRGCLS---KFECTD---SIFPVVTCPKCHMQSG-SLSSLKPYITQYAIES-----KEINVSTIDFN------DFKCVLCTS----GEDSKYKCVDCAGLLCERCKILHKEVKFLNSHLEVEELTDEDKTNIKLLKKHLADNKPVKCEVHCERKYTNYCIQCGMLACSRCLLSDHADHSTVLLQDFPEKIRFRIGNYIENCIKAEEMNKIAIEKLNNALMEVNNSHDENKTHIEEVCNEWKTAIDDIKTEYLKKNKELHDD 290

The following BLAST results are available for this feature:

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Human
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Celegans
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Fly
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Zebrafish
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Xenopus
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Mouse
BLAST of Tripartite motif-containing protein 2 vs. UniProt/SwissProt
BLAST of Tripartite motif-containing protein 2 vs. TrEMBL
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Cavefish
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Sea Lamprey
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Yeast
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Nematostella
BLAST of Tripartite motif-containing protein 2 vs. Ensembl Medaka
BLAST of Tripartite motif-containing protein 2 vs. Planmine SMEST

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TRIM56	5.072e-30	26.32	tripartite motif containing 56 [Source:HGNC Symbol...	[more]
TRIM56	8.909e-30	26.07	tripartite motif containing 56 [Source:HGNC Symbol...	[more]
TRIM45	9.116e-23	23.29	tripartite motif containing 45 [Source:HGNC Symbol...	[more]
TRIM45	9.231e-23	23.29	tripartite motif containing 45 [Source:HGNC Symbol...	[more]
TRIM2	6.288e-20	24.23	tripartite motif containing 2 [Source:HGNC Symbol;...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nhl-2	8.165e-14	22.50	NHL (Ring finger b-box coiled coil) domain contain...	[more]
nhl-1	1.658e-11	30.37	RING finger protein nhl-1 [Source:UniProtKB/Swiss...	[more]
nhl-1	1.784e-11	30.37	RING finger protein nhl-1 [Source:UniProtKB/Swiss...	[more]
arc-1	5.449e-8	23.01	E3 ubiquitin-protein ligase arc-1 [Source:UniProt...	[more]
nhl-3	1.667e-6	26.09	NHL (Ring finger b-box coiled coil) domain contain...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mei-P26	8.553e-22	23.56	gene:FBgn0026206 transcript:FBtr0474151	[more]
mei-P26	9.677e-22	23.56	gene:FBgn0026206 transcript:FBtr0333474	[more]
mei-P26	9.677e-22	23.56	gene:FBgn0026206 transcript:FBtr0340341	[more]
mei-P26	9.688e-22	23.56	gene:FBgn0026206 transcript:FBtr0333473	[more]
mei-P26	9.688e-22	23.56	gene:FBgn0026206 transcript:FBtr0071303	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trim2a	3.053e-23	25.82	tripartite motif containing 2a [Source:ZFIN;Acc:ZD...	[more]
trim24	7.414e-21	27.76	tripartite motif containing 24 [Source:ZFIN;Acc:ZD...	[more]
trim3a	8.575e-20	22.34	tripartite motif containing 3a [Source:ZFIN;Acc:ZD...	[more]
ftr56	1.040e-19	28.84	finTRIM family, member 56 [Source:ZFIN;Acc:ZDB-GEN...	[more]
trim45	3.137e-18	24.53	tripartite motif containing 45 [Source:ZFIN;Acc:ZD...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
actr6	2.716e-20	24.47	ARP6 actin related protein 6 homolog [Source:Xenba...	[more]
actr6	2.943e-20	24.47	ARP6 actin related protein 6 homolog [Source:Xenba...	[more]
actr6	3.303e-20	24.47	ARP6 actin related protein 6 homolog [Source:Xenba...	[more]
trim45	3.132e-19	24.26	tripartite motif containing 45 [Source:NCBI gene;A...	[more]
TRIM33	1.541e-17	26.49	tripartite motif containing 33 [Source:NCBI gene;A...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Trim56	2.053e-29	27.59	tripartite motif-containing 56 [Source:MGI Symbol;...	[more]
Trim56	3.059e-26	31.34	tripartite motif-containing 56 [Source:MGI Symbol;...	[more]
Trim45	7.069e-22	22.64	tripartite motif-containing 45 [Source:MGI Symbol;...	[more]
Trim45	1.545e-21	23.14	tripartite motif-containing 45 [Source:MGI Symbol;...	[more]
Trim45	1.545e-21	23.14	tripartite motif-containing 45 [Source:MGI Symbol;...	[more]

BLAST of Tripartite motif-containing protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|E1BD59\|TRI56_BOVIN	6.432e-31	26.79	E3 ubiquitin-protein ligase TRIM56 OS=Bos taurus O...	[more]
sp\|Q9BRZ2\|TRI56_HUMAN	2.436e-29	26.32	E3 ubiquitin-protein ligase TRIM56 OS=Homo sapiens...	[more]
sp\|Q80VI1\|TRI56_MOUSE	1.338e-28	27.59	E3 ubiquitin-protein ligase TRIM56 OS=Mus musculus...	[more]
sp\|Q5BIM1\|TRI45_BOVIN	3.381e-23	24.22	Tripartite motif-containing protein 45 OS=Bos taur...	[more]
sp\|Q9H8W5\|TRI45_HUMAN	4.433e-22	23.29	Tripartite motif-containing protein 45 OS=Homo sap...	[more]

BLAST of Tripartite motif-containing protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0L8HBK4	2.248e-126	48.22	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
A0A1S3IWQ5	1.360e-124	44.67	E3 ubiquitin-protein ligase TRIM56 isoform X1 OS=L...	[more]
K1QSK1	1.585e-124	46.20	Tripartite motif-containing protein 56 OS=Crassost...	[more]
A0A1S3IYJ9	6.146e-124	46.20	E3 ubiquitin-protein ligase TRIM56 isoform X2 OS=L...	[more]
A0A1I8HGK2	2.575e-120	46.78	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trim2a	9.455e-22	23.32	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
trim2a	9.455e-22	23.32	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
trim2a	9.455e-22	23.32	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
trim2a	1.012e-21	23.32	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
trim45	1.259e-20	23.76	tripartite motif-containing protein 45-like [Sourc...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000010730.1	1.506e-12	38.20	pep scaffold:Pmarinus_7.0:GL485872:9458:10706:1 ge...	[more]
ENSPMAT00000005270.1	9.015e-10	24.12	pep scaffold:Pmarinus_7.0:GL480405:17764:25842:-1 ...	[more]
trim59	3.842e-9	30.34	tripartite motif containing 59 [Source:ZFIN;Acc:ZD...	[more]
ENSPMAT00000004722.1	1.109e-7	28.57	pep scaffold:Pmarinus_7.0:GL477448:190469:194693:-...	[more]
ENSPMAT00000000299.1	1.194e-6	23.81	pep scaffold:Pmarinus_7.0:GL484837:4300:10751:-1 g...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47715	6.063e-29	24.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34308	7.807e-28	24.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47716	5.710e-27	25.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49584	1.199e-23	22.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30616	1.629e-22	26.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trim2a	7.725e-23	25.53	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
trim2a	7.725e-23	25.53	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
trim2a	7.725e-23	25.53	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
trim2a	7.725e-23	25.53	tripartite motif containing 2 [Source:NCBI gene;Ac...	[more]
ENSORLT00000003321.2	2.478e-20	25.56	tripartite motif-containing protein 16-like [Sourc...	[more]

BLAST of Tripartite motif-containing protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000023375.1	0.000e+0	99.66	SMESG000023375.1	[more]
SMESG000023375.1	0.000e+0	99.63	SMESG000023375.1	[more]
SMESG000035122.1	1.284e-9	24.89	SMESG000035122.1	[more]
SMESG000035122.1	1.403e-9	24.89	SMESG000035122.1	[more]
SMESG000059098.1	5.476e-9	21.89	SMESG000059098.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30030752 ID=SMED30030752|Name=Tripartite motif-containing protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2122bp
CAAAATTACACACAAAGTTTTTTGCGATATGTTCGCCTAATAACTAGGTA
TTGATTTTAACACTAAAATATTCAGAAATAAGCAATGAATCATTAGGGGA
TTACACAATATAGACCAATATCGAATCAGCATGAATAAAAAAAATTCCCC
ATAAATCTGAGCATTAGTTTTAAATCTTTTAGTATTTCTATGACAGAAGA
ATCTTCATCTCGAATATATCGCAGAAGATTTGGAAAACCTTCAGGAATGC
TATTGTCTTACAATTCTAATGAAAAAAAGCATGAAAGACCAATGTCTTGG
ATACCAACCAGTGATTTTTTGAAGACATTCAATGGCGATACATTGGGAAG
TAATTTAAATGATGCAGAAATTTTTAAATCTACTTCTAAAAGTCCAGCAC
ATTCAGTTCAAAATGAAAATATTCAAGCAATAGGAGGGAAATTAGCTCAA
GAAATTCAAGATGAATTATTAATATGTAAGATTTGTCTTGAAAATTACAA
GCAACCAAAAAGCCTTTCTTGTTTACATACATTTTGTGCTGAATGCCTTG
AAAATCATATACAAGGTGAAGTAACCTATAAAAAATACAGTGATTACAGG
GAATTTACTTGTCCACTATGCCGAAAGAGAACTACGTTACCAATGGGTGG
TGTACGAAAATTACCGGACAATTTTGTTGTTGCCAGTCTTTTTGAGATGA
TTAAAAAAAGAAAAGATTCAGTGACTGATTTGACCAGTGAGGAATCTACT
ACTAATTTCTTTTGTCAAATTTGTCGAAAATTGAACAACAGAAAAAGAGA
GGCTCAAACAAAATGCATTGATTGTAGCAAACTTTTATGTCGTAATTGCA
CAGAGATTCATCGACAAACCAAAGTTACTCAACAACATTCATTGTTTGAT
TTGAATATTGAGAATGATGTAATTTGTAAAATTCACCCTGAGGAGTCGGT
TAGGTTTTTTTGTAAACCCTGTCAAGCTTGTATATGCGTATTGTGCACAT
TCAACGAGCATAGTGACCATGAAATTACTCAATTTAACGAAGCCGTTGTG
AAATATAAGTCAGACATTGAACAACAACTTAGTTTCTCTCAGGAAATTAT
TTCTCAATGTGAAATTAAACTTTCTAAAATAAATAATGTGGAACAGATCA
TTAAATCTACAGAAAATCAGATAAAGGAGATGGCATCAAAACTTATACTG
GAGATAAGACACAAAGAAAGTCAACTGTTGGAAGAAATACGAAATCTTTA
TGGTGACAATATGATTGACATAATCGAATCAAAGTCTGTCATGGAAAATC
AACTGTCAGAATTAAAGAACACGTGCAACATGGCTGAAGTCATTTTACAA
AGAAAAGATATTGAGTTGTTATTATTGCAAAAAGAAATCCAAGAGAAATT
GTTGGAATCACAAAAGTTGCCTGAAAACGAGTTGCCGCTATCTGTAATGA
AAGAAGTCAAATTCATTCCGGGAGTTTTTGAGTTTGGTTGCTTGCAAGAT
ATGGACAGGCCAATGCTAACTAGACCGAATTTCCGGATTTTCAACGACTA
CATGTCTCAAGAAATACCGAAACCTGATCAGAAGTGTGTGGAAACTCAAA
CAGATATAGAAATTACAAAACCTAACACAGCTTCAAAGTCTATCTCAACA
ATACCGGTTCAAATTGCTAATAAAGCAGTGAATACACGTACAAGAGTCAT
TCAACAGAAACCTCGAACGAATTCTGTTCAATTTACTAACGGTTCATCGA
ATCTTATTGAGATTCAACCGATCACATCTAATGAAGGAAAAATAATGTTC
GTGAATTCCGACAAATTGCTCCTTTCGCCTTCGACTCGCCGACGACTATC
TCAGGCTGAAAAGTCAAAATCAAATGACACAAAAGATCTAATTATTACCG
CTTCTGAAATTCTGAATGATTTTATTGCCCAAGTGAATTTGGAAACAGAA
GATGCTGCCAAATTAGACTAAATATCTCGAAAGTACCGGTGAAATCTTCG
TTTCCGTTGTTGATTACATTGTCAAATAAGACATTTATTTGACTCCTCTT
ATGTATAATATGTGACTGACTTCTCTTTTGTATTAGTGTGATAAAATATT
GTTAGAATAATCAAACCTTTAT

protein sequence of SMED30030752-orf-1

>SMED30030752-orf-1 ID=SMED30030752-orf-1|Name=SMED30030752-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=594bp
MTEESSSRIYRRRFGKPSGMLLSYNSNEKKHERPMSWIPTSDFLKTFNGD
TLGSNLNDAEIFKSTSKSPAHSVQNENIQAIGGKLAQEIQDELLICKICL
ENYKQPKSLSCLHTFCAECLENHIQGEVTYKKYSDYREFTCPLCRKRTTL
PMGGVRKLPDNFVVASLFEMIKKRKDSVTDLTSEESTTNFFCQICRKLNN
RKREAQTKCIDCSKLLCRNCTEIHRQTKVTQQHSLFDLNIENDVICKIHP
EESVRFFCKPCQACICVLCTFNEHSDHEITQFNEAVVKYKSDIEQQLSFS
QEIISQCEIKLSKINNVEQIIKSTENQIKEMASKLILEIRHKESQLLEEI
RNLYGDNMIDIIESKSVMENQLSELKNTCNMAEVILQRKDIELLLLQKEI
QEKLLESQKLPENELPLSVMKEVKFIPGVFEFGCLQDMDRPMLTRPNFRI
FNDYMSQEIPKPDQKCVETQTDIEITKPNTASKSISTIPVQIANKAVNTR
TRVIQQKPRTNSVQFTNGSSNLIEIQPITSNEGKIMFVNSDKLLLSPSTR
RRLSQAEKSKSNDTKDLIITASEILNDFIAQVNLETEDAAKLD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001841	Znf_RING
IPR000315	Znf_B-box
IPR013083	Znf_RING/FYVE/PHD
IPR027370	Znf-RING_LisH
IPR017907	Znf_RING_CS

Vocabulary: **molecular function**
Term	Definition
GO:0008270	zinc ion binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 314..334
None	No IPR available	GENE3D	G3DSA:3.30.40.90		coord: 169..237 e-value: 1.1E-5 score: 27.3
None	No IPR available	GENE3D	G3DSA:3.30.40.200		coord: 238..302 e-value: 9.2E-13 score: 49.7
None	No IPR available	PANTHER	PTHR25462	FAMILY NOT NAMED	coord: 86..546
None	No IPR available	PANTHER	PTHR25462:SF261		coord: 86..546
None	No IPR available	SUPERFAMILY	SSF57845	B-box zinc-binding domain	coord: 242..299
None	No IPR available	SUPERFAMILY	SSF57850	RING/U-box	coord: 91..171
IPR001841	Zinc finger, RING-type	SMART	SM00184	ring_2	coord: 192..264 e-value: 18.0 score: 0.4 coord: 96..144 e-value: 1.0E-7 score: 41.6
IPR001841	Zinc finger, RING-type	PROSITE	PS50089	ZF_RING_2	coord: 96..145 score: 12.327
IPR000315	B-box-type zinc finger	SMART	SM00336	bboxneu5	coord: 187..238 e-value: 1.6 score: 5.3 coord: 241..282 e-value: 5.3E-7 score: 39.3
IPR000315	B-box-type zinc finger	PFAM	PF00643	zf-B_box	coord: 243..280 e-value: 4.8E-9 score: 36.2
IPR000315	B-box-type zinc finger	PROSITE	PS50119	ZF_BBOX	coord: 241..282 score: 11.405
IPR000315	B-box-type zinc finger	PROSITE	PS50119	ZF_BBOX	coord: 187..238 score: 9.584
IPR000315	B-box-type zinc finger	CDD	cd00021	BBOX	coord: 244..277 e-value: 4.33165E-10 score: 53.0599
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 83..168 e-value: 9.2E-17 score: 62.0
IPR027370	RING-type zinc-finger, LisH dimerisation motif	PFAM	PF13445	zf-RING_UBOX	coord: 96..142 e-value: 3.6E-10 score: 39.7
IPR017907	Zinc finger, RING-type, conserved site	PROSITE	PS00518	ZF_RING_1	coord: 111..120

Main menu

Tripartite motif-containing protein 2

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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