Fibroblast growth factor receptor

Overview
NameFibroblast growth factor receptor
Smed IDSMED30030751
Length (bp)1847
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Fibroblast growth factor receptor (SMED30030751) t-SNE clustered cells

Violin plots show distribution of expression levels for Fibroblast growth factor receptor (SMED30030751) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Fibroblast growth factor receptor (SMED30030751) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Fibroblast growth factor receptor (SMED30030751) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30030751

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30030751SMESG000022068.1 SMESG000022067.1 SmedASXL_016449SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
gutSMED30030751SMESG000022068.1 SMESG000022067.1 SMED30030751smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30030751SMESG000022068.1 SMESG000022067.1 SMED30030751smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30030751SMESG000022068.1 SMESG000022067.1 SMED30030751smed_20140614PMID:27523733
Lei et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30030751SMESG000022068.1 SMESG000022067.1 SMED30030751smed_20140614PMID:27523733
Lei et al., 2016		whole organism asexual adult fluorescence in situ hybridization evidence
neoblastSMED30030751SMESG000022068.1 SMED_21601_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30030751SMESG000022068.1 SMED_21601_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 189.889 bits (481), Expect = 3.449e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  398 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 670
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 189.889 bits (481), Expect = 4.032e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  398 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 670
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 189.504 bits (480), Expect = 4.662e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  396 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 668
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 189.889 bits (481), Expect = 7.354e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  477 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 749
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 189.889 bits (481), Expect = 8.356e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  485 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 757
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 174.866 bits (442), Expect = 7.627e-46
Identity = 105/281 (37.37%), Postives = 150/281 (53.38%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSG---NFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ----------------LSP------------SNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA-CN-YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDII 1701
             G FGEV+  KAT    +N    VAVK LK +A      + + E +    +G+H+N+++ IG       + +V+E  K+G+L + L+A +                L P             N  +R L QF   VA GM +L+S  +IHRDLAARNV V +  VLKI DFGL+R+  CN YYR+   G++PI+W+ALE+L    Y+  SD+WS+G+LLWEI +LG TPY  +    L  +L   G R   P  C   +Y++M   W     ERP+F  I+
Sbjct:  648 EGAFGEVW--KATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANL-KEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIV 925
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 174.866 bits (442), Expect = 7.627e-46
Identity = 105/281 (37.37%), Postives = 150/281 (53.38%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSG---NFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ----------------LSP------------SNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA-CN-YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDII 1701
             G FGEV+  KAT    +N    VAVK LK +A      + + E +    +G+H+N+++ IG       + +V+E  K+G+L + L+A +                L P             N  +R L QF   VA GM +L+S  +IHRDLAARNV V +  VLKI DFGL+R+  CN YYR+   G++PI+W+ALE+L    Y+  SD+WS+G+LLWEI +LG TPY  +    L  +L   G R   P  C   +Y++M   W     ERP+F  I+
Sbjct:  648 EGAFGEVW--KATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANL-KEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIV 925
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 174.866 bits (442), Expect = 7.627e-46
Identity = 105/281 (37.37%), Postives = 150/281 (53.38%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSG---NFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ----------------LSP------------SNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA-CN-YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDII 1701
             G FGEV+  KAT    +N    VAVK LK +A      + + E +    +G+H+N+++ IG       + +V+E  K+G+L + L+A +                L P             N  +R L QF   VA GM +L+S  +IHRDLAARNV V +  VLKI DFGL+R+  CN YYR+   G++PI+W+ALE+L    Y+  SD+WS+G+LLWEI +LG TPY  +    L  +L   G R   P  C   +Y++M   W     ERP+F  I+
Sbjct:  648 EGAFGEVW--KATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANL-KEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIV 925
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 174.866 bits (442), Expect = 7.627e-46
Identity = 105/281 (37.37%), Postives = 150/281 (53.38%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSG---NFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ----------------LSP------------SNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA-CN-YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDII 1701
             G FGEV+  KAT    +N    VAVK LK +A      + + E +    +G+H+N+++ IG       + +V+E  K+G+L + L+A +                L P             N  +R L QF   VA GM +L+S  +IHRDLAARNV V +  VLKI DFGL+R+  CN YYR+   G++PI+W+ALE+L    Y+  SD+WS+G+LLWEI +LG TPY  +    L  +L   G R   P  C   +Y++M   W     ERP+F  I+
Sbjct:  648 EGAFGEVW--KATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANL-KEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIV 925
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 174.866 bits (442), Expect = 7.646e-46
Identity = 105/281 (37.37%), Postives = 150/281 (53.38%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSG---NFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ----------------LSP------------SNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA-CN-YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDII 1701
             G FGEV+  KAT    +N    VAVK LK +A      + + E +    +G+H+N+++ IG       + +V+E  K+G+L + L+A +                L P             N  +R L QF   VA GM +L+S  +IHRDLAARNV V +  VLKI DFGL+R+  CN YYR+   G++PI+W+ALE+L    Y+  SD+WS+G+LLWEI +LG TPY  +    L  +L   G R   P  C   +Y++M   W     ERP+F  I+
Sbjct:  648 EGAFGEVW--KATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANL-KEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIV 925
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Fly
Match: btl (gene:FBgn0285896 transcript:FBtr0100676)

HSP 1 Score: 191.43 bits (485), Expect = 3.112e-51
Identity = 109/319 (34.17%), Postives = 166/319 (52.04%), Query Frame = 1 
Query:  862 NYSFPTDLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKY--TLVAVKLLKH---NAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ-------------------LSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTR--EACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSDCSCN 1740
             Y FP D    S + + +Q       L      G FG V + +A       +   T+VAVK++K    +    + + E ++M  +G H NII  +G  +    + +++EYA +G+L + LK  +                   +S  +  E+ L +F   +A GMEYL+S   IHRDLAARNV VS+ +V+KI DFGL R  +   YYR+   G++PI+W+A ESL  KKY + SD+WS+G+LLWEI + G  PY  +     L   ++ G+R  +P  C L IY +M++ WH  +  RPTF +++     I    S N
Sbjct:  696 EYEFPLD----SNWEIPRQQLSLGSILG----EGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSN 1006
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Fly
Match: btl (gene:FBgn0285896 transcript:FBtr0075778)

HSP 1 Score: 191.43 bits (485), Expect = 3.112e-51
Identity = 109/319 (34.17%), Postives = 166/319 (52.04%), Query Frame = 1 
Query:  862 NYSFPTDLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKY--TLVAVKLLKH---NAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ-------------------LSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTR--EACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSDCSCN 1740
             Y FP D    S + + +Q       L      G FG V + +A       +   T+VAVK++K    +    + + E ++M  +G H NII  +G  +    + +++EYA +G+L + LK  +                   +S  +  E+ L +F   +A GMEYL+S   IHRDLAARNV VS+ +V+KI DFGL R  +   YYR+   G++PI+W+A ESL  KKY + SD+WS+G+LLWEI + G  PY  +     L   ++ G+R  +P  C L IY +M++ WH  +  RPTF +++     I    S N
Sbjct:  696 EYEFPLD----SNWEIPRQQLSLGSILG----EGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSN 1006
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0300549)

HSP 1 Score: 184.496 bits (467), Expect = 1.270e-49
Identity = 102/254 (40.16%), Postives = 150/254 (59.06%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVH---GKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELK 1713
            GEFG+V LG     N+K     VAVK+LK       F+ E  +M  L +HDN++K+IG +     + +V EY   GSL++ L++         ++I+  F  D ASGMEYL +  ++HRDLAARNV +SE  V K+ DFGL RE C     ++ GK+PI+W A E+L   ++S  SD+WSFGILLWEI+S G+ PY  +     L D++ H   G +   P  C   IY +M++ W    ++RPTF ++ ++L+
Sbjct:  480 GEFGDVMLG--ILRNEK-----VAVKMLKDEGAVQKFLAEASVMTTL-EHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQII--FAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREEC---YNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIP----LADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQ 716
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0300547)

HSP 1 Score: 184.496 bits (467), Expect = 1.270e-49
Identity = 102/254 (40.16%), Postives = 150/254 (59.06%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVH---GKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELK 1713
            GEFG+V LG     N+K     VAVK+LK       F+ E  +M  L +HDN++K+IG +     + +V EY   GSL++ L++         ++I+  F  D ASGMEYL +  ++HRDLAARNV +SE  V K+ DFGL RE C     ++ GK+PI+W A E+L   ++S  SD+WSFGILLWEI+S G+ PY  +     L D++ H   G +   P  C   IY +M++ W    ++RPTF ++ ++L+
Sbjct:  480 GEFGDVMLG--ILRNEK-----VAVKMLKDEGAVQKFLAEASVMTTL-EHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQII--FAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREEC---YNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIP----LADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQ 716
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Fly
Match: Csk (gene:FBgn0262081 transcript:FBtr0300548)

HSP 1 Score: 184.496 bits (467), Expect = 1.270e-49
Identity = 102/254 (40.16%), Postives = 150/254 (59.06%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVH---GKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELK 1713
            GEFG+V LG     N+K     VAVK+LK       F+ E  +M  L +HDN++K+IG +     + +V EY   GSL++ L++         ++I+  F  D ASGMEYL +  ++HRDLAARNV +SE  V K+ DFGL RE C     ++ GK+PI+W A E+L   ++S  SD+WSFGILLWEI+S G+ PY  +     L D++ H   G +   P  C   IY +M++ W    ++RPTF ++ ++L+
Sbjct:  480 GEFGDVMLG--ILRNEK-----VAVKMLKDEGAVQKFLAEASVMTTL-EHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQII--FAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREEC---YNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIP----LADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQ 716
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Zebrafish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 182.956 bits (463), Expect = 1.468e-51
Identity = 101/277 (36.46%), Postives = 157/277 (56.68%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLS-----------PSNT---NERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
             G FG+V + +A   + +  NK   VAVK+LK +       + + E ++M  +G H NII  +G       + +++EYA  G+L   L+A +             P+ T    + + C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+  N  YY++   G++P++W+A E+L  + Y+  SD+WS+G+LLWEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y IM++ WH + S+RPTF  ++ +   + S
Sbjct:   50 EGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAY--QVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRVLS 323
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Zebrafish
Match: fgfr1b (fibroblast growth factor receptor 1b [Source:ZFIN;Acc:ZDB-GENE-060503-14])

HSP 1 Score: 187.193 bits (474), Expect = 2.263e-50
Identity = 103/269 (38.29%), Postives = 157/269 (58.36%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ------------LSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA--CNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILEL 1710
            G FG+V +G+A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++E+A  G+L   L+A +            L   + + + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + ++RPTF  ++ +L
Sbjct:  406 GCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPHGMEYCYNPDPLPIESMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDL 673
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Zebrafish
Match: fgfr1b (fibroblast growth factor receptor 1b [Source:ZFIN;Acc:ZDB-GENE-060503-14])

HSP 1 Score: 186.808 bits (473), Expect = 3.716e-50
Identity = 104/274 (37.96%), Postives = 158/274 (57.66%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ------------LSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA--CNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V +G+A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++E+A  G+L   L+A +            L   + + + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + ++RPTF  ++ +L    S
Sbjct:  432 GCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPHGMEYCYNPDPLPIESMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDLDRTLS 704
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Zebrafish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 185.267 bits (469), Expect = 5.726e-50
Identity = 101/270 (37.41%), Postives = 154/270 (57.04%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAF------------QLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILEL 1710
             G FG+V + +A   + +  N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++E+A  G+L   L+              Q+   N + + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L
Sbjct:  359 EGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDL 627
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Zebrafish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 185.267 bits (469), Expect = 5.726e-50
Identity = 101/270 (37.41%), Postives = 154/270 (57.04%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAF------------QLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILEL 1710
             G FG+V + +A   + +  N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++E+A  G+L   L+              Q+   N + + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L
Sbjct:  359 EGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDL 627
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Xenopus
Match: tirap (toll-interleukin 1 receptor (TIR) domain containing adaptor protein [Source:Xenbase;Acc:XB-GENE-920263])

HSP 1 Score: 189.504 bits (480), Expect = 1.546e-51
Identity = 105/274 (38.32%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNERIL-------CQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG+V + +A   + +  NK T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +P+   +++L       C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I
Sbjct:  324 GCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPTCAPDQLLSFKDLVSCAY--QVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-MEELFKLLKEGHRMDKPTTCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRI 594
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Xenopus
Match: tirap (toll-interleukin 1 receptor (TIR) domain containing adaptor protein [Source:Xenbase;Acc:XB-GENE-920263])

HSP 1 Score: 189.504 bits (480), Expect = 1.918e-51
Identity = 105/274 (38.32%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNERIL-------CQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG+V + +A   + +  NK T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +P+   +++L       C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I
Sbjct:  341 GCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPTCAPDQLLSFKDLVSCAY--QVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-MEELFKLLKEGHRMDKPTTCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRI 611
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Xenopus
Match: tirap (toll-interleukin 1 receptor (TIR) domain containing adaptor protein [Source:Xenbase;Acc:XB-GENE-920263])

HSP 1 Score: 189.119 bits (479), Expect = 1.936e-51
Identity = 105/274 (38.32%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNERIL-------CQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG+V + +A   + +  NK T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +P+   +++L       C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I
Sbjct:  313 GCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPTCAPDQLLSFKDLVSCAY--QVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-MEELFKLLKEGHRMDKPTTCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRI 583
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Xenopus
Match: c1orf84 (chromosome 1 open reading frame 84 [Source:Xenbase;Acc:XB-GENE-6041758])

HSP 1 Score: 188.734 bits (478), Expect = 6.817e-51
Identity = 152/533 (28.52%), Postives = 253/533 (47.47%), Query Frame = 1 
Query:  268 LSFKHVCPTDLGIYQCMIVHDYIDSSDISNMNVITKQVVYKPIKIEIIFNHLDKPCLNSNIRLRCNVTPRAFDVQLFMR------RNNQFIGRKMKKFIRCKNKTVTMFDNSPIEYKISNATINDSGIYYCQALYDY--QYSKMINLKFQQCS-NKSDGYLQFNTLIVGLMIGLFLPLFALVLFCI--KKRVGSKITPKYGKALGVDSQNYSFPTDLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFN-DKNKYTL-VAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA---FQLSPSNTNERI---------LCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI--------YSDCSCNLVRY 1752
            L  + V P+D GIY C++ +++   +   +++VI +   ++PI ++          +  +    C V     D Q  +R      +N    G     +I+   ++     ++ +  K+ N T  D+G Y C A+ +Y  + +K   L       N    Y++      G+ I     +F +V+ C+  + R G+K             +N++ P          L K +             G FG+V + +A   + D+ K ++ VAVK+LK +A      + + E ++M  +G H NII  +G       + +++EYA  G+L   L+A    ++  S    R+         L      +A GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+  N  YY++   G++P++W+A E+L  + Y+  SD+WSFG+L+WEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y +M+  WH I S RPTF  ++ +L  I        Y D S  L +Y
Sbjct:  185 LIMESVVPSDKGIYTCIVENEHGSINHTYHLDVIERSS-HRPI-LQAGLPANTTAMVGGDAEFVCKVY---SDAQPHIRWVRYIEKNGSRFGVDGLPYIKVLKRSGINSSSAEV-LKLYNVTEEDAGEYIC-AVSNYIGEANKSAWLTVDPGEDNPVPYYMEIGIYSAGIFI-----IFCMVVICVVCRMRQGAK-----------KKKNFTGP------PVLTLGKPLG-----------EGCFGQVVMAEALGIDKDRPKESVTVAVKMLKDDATEKDLADLVSEMEMMKIIGKHKNIINLLGACTQGGTLYVIVEYAAKGNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDVNNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAIPSHRPTFKQLVEDLDRILTLTTNEEYLDLSAPLEQY 676
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Xenopus
Match: tirap (toll-interleukin 1 receptor (TIR) domain containing adaptor protein [Source:Xenbase;Acc:XB-GENE-920263])

HSP 1 Score: 189.889 bits (481), Expect = 7.054e-51
Identity = 105/274 (38.32%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNERIL-------CQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG+V + +A   + +  NK T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +P+   +++L       C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I
Sbjct:  471 GCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPTCAPDQLLSFKDLVSCAY--QVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-MEELFKLLKEGHRMDKPTTCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRI 741
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Mouse
Match: Fgfr1 (fibroblast growth factor receptor 1 [Source:MGI Symbol;Acc:MGI:95522])

HSP 1 Score: 189.889 bits (481), Expect = 2.636e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  398 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 670
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Mouse
Match: Fgfr1 (fibroblast growth factor receptor 1 [Source:MGI Symbol;Acc:MGI:95522])

HSP 1 Score: 189.889 bits (481), Expect = 2.636e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  398 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 670
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Mouse
Match: Fgfr1 (fibroblast growth factor receptor 1 [Source:MGI Symbol;Acc:MGI:95522])

HSP 1 Score: 189.889 bits (481), Expect = 2.768e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  398 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 670
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Mouse
Match: Fgfr1 (fibroblast growth factor receptor 1 [Source:MGI Symbol;Acc:MGI:95522])

HSP 1 Score: 189.889 bits (481), Expect = 6.348e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  487 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 759
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Mouse
Match: Fgfr1 (fibroblast growth factor receptor 1 [Source:MGI Symbol;Acc:MGI:95522])

HSP 1 Score: 189.504 bits (480), Expect = 6.692e-51
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  485 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 757
[Close]
BLAST of Fibroblast growth factor receptor vs. UniProt/SwissProt
Match: sp|Q8MY86|FGFR1_DUGJA (Fibroblast growth factor receptor 1 OS=Dugesia japonica OX=6161 GN=FGFR1 PE=2 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 1.101e-52
Identity = 101/263 (38.40%), Postives = 155/263 (58.94%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGN---FIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSP-------SNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG VY G A    +++    VAVK+++ +    N   F+ E +IM ++G H N+I+ +G       + +++E A  G+L + ++A             N    ILC + + +A GM YL+S +++HRDL+ARN+ V E + +KI DFGLTR    YYR+  +G +P++W+A E+LL KKY+T SD+WS+GILLWEIF+LG +PY  +    ++ DLI  G +N +P      IY +MQ  W   +  RP F +I+  L DI
Sbjct:  560 GAFGMVYEGIANDIGNRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQIARGMTYLASRSVVHRDLSARNILVGEHFEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVV-DLIRKGFQNPKPELANFEIYRLMQHCWSLSSENRPNFFEIVEILIDI 821
[Close]
BLAST of Fibroblast growth factor receptor vs. UniProt/SwissProt
Match: sp|Q09147|FGFR2_DROME (Fibroblast growth factor receptor homolog 2 OS=Drosophila melanogaster OX=7227 GN=btl PE=2 SV=3)

HSP 1 Score: 191.43 bits (485), Expect = 3.119e-50
Identity = 109/319 (34.17%), Postives = 166/319 (52.04%), Query Frame = 1 
Query:  862 NYSFPTDLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKY--TLVAVKLLKH---NAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ-------------------LSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTR--EACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSDCSCN 1740
             Y FP D    S + + +Q       L      G FG V + +A       +   T+VAVK++K    +    + + E ++M  +G H NII  +G  +    + +++EYA +G+L + LK  +                   +S  +  E+ L +F   +A GMEYL+S   IHRDLAARNV VS+ +V+KI DFGL R  +   YYR+   G++PI+W+A ESL  KKY + SD+WS+G+LLWEI + G  PY  +     L   ++ G+R  +P  C L IY +M++ WH  +  RPTF +++     I    S N
Sbjct:  696 EYEFPLD----SNWEIPRQQLSLGSILG----EGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSN 1006
[Close]
BLAST of Fibroblast growth factor receptor vs. UniProt/SwissProt
Match: sp|P11362|FGFR1_HUMAN (Fibroblast growth factor receptor 1 OS=Homo sapiens OX=9606 GN=FGFR1 PE=1 SV=3)

HSP 1 Score: 189.889 bits (481), Expect = 4.152e-50
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  487 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 759
[Close]
BLAST of Fibroblast growth factor receptor vs. UniProt/SwissProt
Match: sp|P16092|FGFR1_MOUSE (Fibroblast growth factor receptor 1 OS=Mus musculus OX=10090 GN=Fgfr1 PE=1 SV=2)

HSP 1 Score: 189.889 bits (481), Expect = 4.441e-50
Identity = 108/274 (39.42%), Postives = 160/274 (58.39%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNE-----RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +PS+  E     + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  487 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 759
[Close]
BLAST of Fibroblast growth factor receptor vs. UniProt/SwissProt
Match: sp|Q91285|FGFR1_PLEWA (Fibroblast growth factor receptor 1 OS=Pleurodeles waltl OX=8319 GN=FGFR1 PE=2 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 7.863e-50
Identity = 105/276 (38.04%), Postives = 162/276 (58.70%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA-------FQLSPSNTNERIL-------CQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V +G+A   + +  N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A       +  +P + ++ +L       C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L  I +
Sbjct:  483 GCFGQVVMGEAIGLDKEKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKDLVSCAY--QVARGMEYLASKKCIHRDLAARNVLVTEDSVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVA 755
[Close]
BLAST of Fibroblast growth factor receptor vs. TrEMBL
Match: B0XJJ2 (Testis-specific serine/threonine-protein kinase 6 OS=Culex quinquefasciatus OX=7176 GN=6053788 PE=3 SV=1)

HSP 1 Score: 209.149 bits (531), Expect = 8.766e-56
Identity = 138/418 (33.01%), Postives = 215/418 (51.44%), Query Frame = 1 
Query:  598 KISNATINDSGIYYCQALYDYQYSKMINLK------FQQCSNKSDGYLQFNTLI-VGLMIGLFLPLFALVLFC---IKK----RVGSKITPKYGKALGVDSQNYSFPT--------------------DLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPS-------NTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELK 1713
            K  N + +D+G Y C+A Y   Y K + ++      F Q  N+S     +  L+ V L+I   +  F +  +C   +KK    R+   +T     A G  S+++  P                     DL  +   +L  ++    + L K+LG G FG V  GKA+ F +      VAVK+L+ N       + + E +IM  +G H N+I  +G  +    + +++EYA +G+L N L+ F+   S         + + L  F + +A+GMEYLSS+  IHRDLAARN+ VSE +V+KI DFGL R+  +  YYR++  GKVPIRW+A ESL    + + +D+WSFG+LLWEI +LG  PY  ++    L   +  G R  +P  C   +Y++M++ W     +RP+F  I+  LK
Sbjct:  176 KFENVSFSDAGWYICKAFY---YEKELYIEVANRSVFLQVVNESSEVPLYAILVPVMLLILALMVGFVIYFYCQTQLKKTYYERLIKVVTVSRNAAQG-SSESFQMPVVKIEKHRTVMVQNDAYDSLPDLEYEFPVDLRWELPRQRIVLGKLLGEGAFGRVVQGKASGFAEGANSIPVAVKMLRENHTDEDVKDLVCELEIMKMIGKHPNVISLVGCCSNKGPLYVIIEYATHGNLKNFLRGFRFEGSFDKLDKQAISVQRLVTFALQIATGMEYLSSIKCIHRDLAARNILVSEGYVMKIADFGLARDVQDHEYYRKMTAGKVPIRWMAPESLENFFFDSRTDVWSFGVLLWEIMTLGAQPYQNISAWEHLLQHLKEGNRLKEPTQCPWNVYSVMKECWQITPEQRPSFGGIVERLK 589
[Close]
BLAST of Fibroblast growth factor receptor vs. TrEMBL
Match: R7TUN2 (Protein kinase domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_220531 PE=3 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 2.083e-55
Identity = 137/410 (33.41%), Postives = 211/410 (51.46%), Query Frame = 1 
Query:  601 ISNATINDSGIYYC---QALYDYQYSKMINLKFQQCSNKSDGYLQFNTLIVGLMIGLFLPLFALVLFCIKKRVGSKITPKYGKA--------LGVDSQNYSFPTDL-ITQSTFNLSKQMXXXXXXXXXXXXSGE--FGEVYLGKATSF-NDKNKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLS-PSNTNE--------------RILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTR--EACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            I N   N SG Y C    +  D   S  + +   + +  S+       +++G    L L    L  FC+ +R   + TP   K         + ++  N    +D+ +++    L ++ +    KL      GE  FG V   +AT    DK +   VAVK LK +A      + + E ++M  +G H NII  +G       + +++E+A +G+L + LK+ +L  P   N               R L  FG  VA GMEYL+S   IHRDLAARNV V + +++KI DFGLTR   + +YYR+  +G++P++W+A E+L  +KY+  SD+WS+G+LLWEIFSLG  PY  V  + +L DL+  G R  +P+   L IYN+M + WH    +RP+FTD+  +L  I +
Sbjct:   43 IENVQYNHSGWYTCFVGNSFGDDHTSAWLTV-VPEATVASNHQSTIVAIVIGCCCFLVLAFVVLTGFCVYRRKLLQETPAKRKEPLIRVMPQVRIEGGNRRVMSDISLSEYEIPLDEEWEFPRDKLKIGEPLGEGAFGVVIAAEATGITGDKQRTITVAVKKLKCDATDRELADLVQEMEMMKIIGRHRNIINLLGCCTQSGPLFVIVEFAPHGNLRDFLKSRRLDLPPGCNTGLVRRPNHNKSLSFRDLVSFGYQVARGMEYLASRMCIHRDLAARNVLVGDEYIVKIADFGLTRNIPSQDYYRKTTDGRLPVKWMAPEALFDRKYTVKSDVWSYGVLLWEIFSLGGNPYPSVP-VEMLFDLLRDGHRMERPLHSSLEIYNLMLECWHENPGQRPSFTDLKDDLDRILA 450
[Close]
BLAST of Fibroblast growth factor receptor vs. TrEMBL
Match: A0A2P2ICI7 (Fibroblast growth factor receptor 2-like (Fragment) OS=Hirondellea gigas OX=1518452 PE=2 SV=1)

HSP 1 Score: 205.682 bits (522), Expect = 3.742e-55
Identity = 117/287 (40.77%), Postives = 168/287 (58.54%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSF-NDKNKYTLVAVKLLKH---NAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLS-------------PSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTR--EACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELK--------DIYSDCSCN 1740
            G FG+V+  KA  + NDK  YT VAVK+LK    +A   + + E ++M  +G H NII  IG       + +V+EYA  G+L + L++ Q S             P  T +R L  F   VA GM+YL++   +HRDLAARNV V +  VLKI DFGL R  ++ +YYR+ +EG++P++W+A E+L  + Y++MSD+W+FGILLWEI SLG TPY  V  +  L D++  G R  +P+ C    YN+M+  W   A +RPTF +I++ L         + Y D SC 
Sbjct:  209 GAFGKVH--KAELYPNDKKLYTTVAVKMLKEGHTDAELMDLVSEMEMMKIIGTHQNIINLIGCCTQDGPLYVVVEYAHYGNLRDFLRSSQPSALGYECAVDMDTRPCLT-QRDLIAFAYQVARGMDYLAAKKCVHRDLAARNVLVCQDRVLKIADFGLARDIQSQDYYRKTSEGRLPVKWMAPEALFKRVYTSMSDVWAFGILLWEIMSLGGTPYPSVPSVEELFDILQRGHRMQKPIHCHQDTYNLMRNCWRYNAIDRPTFREILVALSKQLSMVTNEEYLDLSCT 492
[Close]
BLAST of Fibroblast growth factor receptor vs. TrEMBL
Match: A0A1J1J525 (Fibroblast growth factor receptor OS=Clunio marinus OX=568069 GN=CLUMA_CG020474 PE=3 SV=1)

HSP 1 Score: 206.453 bits (524), Expect = 6.056e-54
Identity = 112/305 (36.72%), Postives = 170/305 (55.74%), Query Frame = 1 
Query:  865 YSFPTDL---ITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKYTLVAVKLLKH---NAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLK----------AFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            Y FP DL     ++   L K +             G FG+V +  A       + T+VAVK+LK    +    + + E ++M  +G H NII  +G       + +++EYA +G+L + L+          A +       ++ L  F   +A GMEYL+S   IHRDLAARNV VS+ +V+KI DFGL R+    +YYR+  +G++P++W+A ESL  K Y T SD+WS+GILLWEI +LG TPY  +  +  L +L+  G+R  +P  C + IY +M++TWH    ERP+F++I+ +L  I S
Sbjct:  385 YEFPIDLNWEFPRAQLELGKNLG-----------EGAFGKVVMAHANGLVKTGQTTIVAVKMLKEGHTDEDVKDLVCEMEVMKMIGTHINIINLLGCCCQDGPLFVIVEYAPHGNLRDFLRKHRPNSYADNAQEKEKQTLTQKDLVSFAYQIARGMEYLASRKCIHRDLAARNVLVSDDFVMKIADFGLARDIHTQDYYRKTTDGRLPVKWMAPESLFDKVYDTQSDVWSYGILLWEIMTLGGTPYPSIPSVKNLFELLKKGERMEKPALCSIDIYMLMRETWHWHPMERPSFSEIVEDLDKILS 678
[Close]
BLAST of Fibroblast growth factor receptor vs. TrEMBL
Match: A0A1J1J6U3 (Fibroblast growth factor receptor OS=Clunio marinus OX=568069 GN=CLUMA_CG020474 PE=3 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 6.673e-54
Identity = 112/305 (36.72%), Postives = 170/305 (55.74%), Query Frame = 1 
Query:  865 YSFPTDL---ITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKYTLVAVKLLKH---NAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLK----------AFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            Y FP DL     ++   L K +             G FG+V +  A       + T+VAVK+LK    +    + + E ++M  +G H NII  +G       + +++EYA +G+L + L+          A +       ++ L  F   +A GMEYL+S   IHRDLAARNV VS+ +V+KI DFGL R+    +YYR+  +G++P++W+A ESL  K Y T SD+WS+GILLWEI +LG TPY  +  +  L +L+  G+R  +P  C + IY +M++TWH    ERP+F++I+ +L  I S
Sbjct:  390 YEFPIDLNWEFPRAQLELGKNLG-----------EGAFGKVVMAHANGLVKTGQTTIVAVKMLKEGHTDEDVKDLVCEMEVMKMIGTHINIINLLGCCCQDGPLFVIVEYAPHGNLRDFLRKHRPNSYADNAQEKEKQTLTQKDLVSFAYQIARGMEYLASRKCIHRDLAARNVLVSDDFVMKIADFGLARDIHTQDYYRKTTDGRLPVKWMAPESLFDKVYDTQSDVWSYGILLWEIMTLGGTPYPSIPSVKNLFELLKKGERMEKPALCSIDIYMLMRETWHWHPMERPSFSEIVEDLDKILS 683
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Cavefish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 188.734 bits (478), Expect = 5.240e-51
Identity = 105/269 (39.03%), Postives = 156/269 (57.99%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DK-NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAF------------QLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILEL 1710
            G FG+V +G+    + DK N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++E+A  G+L   L+A             Q+   N + + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH I S+RPTF  ++ +L
Sbjct:  399 GCFGQVVMGEVLGMDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDRPTTCTHELYMMMRDCWHAIPSQRPTFKQLVEDL 666
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Cavefish
Match: fgfr2 (fibroblast growth factor receptor 2 [Source:NCBI gene;Acc:352940])

HSP 1 Score: 185.267 bits (469), Expect = 1.144e-49
Identity = 103/274 (37.59%), Postives = 157/274 (57.30%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFN-DKNKYTL-VAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQL--------------SPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG+V + +A   + DK K  + VAVK+LK +A      + + E ++M  +G H NII  +G       + +++EYA  G+L   L+A +                P    + + C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+  N  YY++   G++P++W+A E+L  + Y+  SD+WSFG+L+WEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y +M+  WH I+S+RPTF  ++ +L  I
Sbjct:  454 GCFGQVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTY--QVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTNDLYMMMKDCWHAISSQRPTFKQLVEDLDRI 724
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Cavefish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 185.267 bits (469), Expect = 1.859e-49
Identity = 134/445 (30.11%), Postives = 212/445 (47.64%), Query Frame = 1 
Query:  589 IEYKISNATINDSGIYYCQA---LYDYQYSKMINLKFQQCS-NKSDGYLQFNTLIVGLMIGLFL----------------------PLFALVLFCIKKRVG----------------SKITPKYGKALGVDSQNYSFPTDL---ITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLS-----------PSNT---NERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            +   +SN T  D+G Y+C A   L   + S  + L+      +K D Y  F  LI G +  LF+                      P+  L  F +K++V                 ++++   G  L   S+    P+D      +S   L K +             G FG+V + +A   + +  NK   VAVK+LK +       + + E ++M  +G H NII  +G       + +++EYA  G+L   L+A +             P+ T    + + C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+  N  YY++   G++P++W+A E+L  + Y+  SD+WS+G+LLWEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y IM++ WH + S+RPTF  ++ +   + S
Sbjct:  328 VRLALSNVTEEDTGQYWCSASNFLGKSELSFWLTLRRPAVELDKEDDYANF--LISGTVCVLFVFTIVIIILCRLRMSTQKTLPTPPVQKLSKFPLKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSE-LELPSDPKWEFPRSKLTLGKALG-----------EGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAY--QVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRVLS 755
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Cavefish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 183.726 bits (465), Expect = 5.845e-49
Identity = 101/276 (36.59%), Postives = 157/276 (56.88%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLS-----------PSNT---NERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V + +A   + +  NK   VAVK+LK +       + + E ++M  +G H NII  +G       + +++EYA  G+L   L+A +             P+ T    + + C +   VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+  N  YY++   G++P++W+A E+L  + Y+  SD+WS+G+LLWEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y IM++ WH + S+RPTF  ++ +   + S
Sbjct:  484 GCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAY--QVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRVLS 756
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Cavefish
Match: met (MET proto-oncogene, receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-041014-1])

HSP 1 Score: 171.014 bits (432), Expect = 1.359e-48
Identity = 87/215 (40.47%), Postives = 134/215 (62.33%), Query Frame = 1 
Query: 1108 HDNIIKYIGFINLPDKIA--IVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEG--KVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSDCS 1734
            H N++  +G I LP + +  +V+ Y K+G L N ++    +P+  +   L  FG+ VA GMEYL+S   +HRDLAARN  + E + +K+ DFGL R+  +  YY   N+   K+P++W+ALESL   K++T SD+WSFG+LLWE+ + G  PY +V     +T  ++ G+R LQP FC  A+YN+M + WH     RPTF++++  +  I+S  S
Sbjct:    6 HPNVLSLLG-ICLPSEGSPLVVLPYMKHGDLRNFIRDETHNPTVKD---LMGFGLQVAKGMEYLASKKFVHRDLAARNCMLDESYTVKVADFGLARDVYDKEYYSVHNKSGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFD-ITVFLLQGRRLLQPEFCPDALYNVMIECWHPKPERRPTFSELVSRISAIFSSFS 215
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Sea Lamprey
Match: fgfr2 (fibroblast growth factor receptor 2 [Source:NCBI gene;Acc:352940])

HSP 1 Score: 187.963 bits (476), Expect = 4.464e-52
Identity = 105/292 (35.96%), Postives = 164/292 (56.16%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPSGNF---IMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA---------FQLSPSNTNERI----LCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREA--CNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI--------YSDCSCNLVRY 1752
            G FG+V + +A   + +  N+   VAVK+LK +A   +    + E ++M N+G H NII  +G       + +++E+A  G+L   L+A         F+ + +   E++    L  F   VA GMEYL+S   IHRDLAARNV V++  V+KI DFGL R+    +YY++ + G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y +M+  W  + S RPTF  ++ +L  I        Y D S  L +Y
Sbjct:  285 GCFGQVVMAEALGIDKEKPNRSLRVAVKMLKEDATDKDLYDLVSEMEMMKNIGKHKNIINLLGACTQGGPLYVIVEFAAKGNLREFLRARRPPGTEYTFEGAAAAQGEQLSIKELVSFTYQVARGMEYLASKKCIHRDLAARNVLVTDDNVMKIADFGLARDVNYIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDRPALCSTELYMMMKDCWAAVPSHRPTFKQLVEDLDRILTMTAQEEYLDLSAPLEQY 575
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Sea Lamprey
Match: NTRK2 (neurotrophic receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:8032])

HSP 1 Score: 173.711 bits (439), Expect = 4.496e-49
Identity = 90/269 (33.46%), Postives = 151/269 (56.13%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLK--HNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLK-----------AFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
             G FG+VYL + +S +   +  LVA K LK   +    +F  E +++ NL  H++I+++ G     + + +V EY KNG L   L+           A Q  P   ++  +   G  +A+GM YL+S + +HRDLA RN  V    V+KIGDFG++R+  + +YYR      +PIRW+  ES++Y+K++  SD+WS G++LWEIF+ G+ P++++++  ++ D I  G+   +P  C + +Y +M   WH     R    DI+  L+ +
Sbjct:   84 EGAFGKVYLAECSSLDVGQEPMLVAAKTLKDLSDGARKDFYREAELLTNL-QHEHIVRFYGVCVEGEPLIMVFEYMKNGDLNKFLRLRGPDAVFMGDAPQAEPRLLSQAQMLNMGSQIAAGMAYLASQHFVHRDLATRNCLVGAGLVVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTADSDVWSLGVVLWEIFTYGKQPWYQLSNTEVI-DCICQGRVLERPRSCPMEVYELMLGCWHREPQHRLGIKDILARLESL 350
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Sea Lamprey
Match: fer (fer (fps/fes related) tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-060526-234])

HSP 1 Score: 170.244 bits (430), Expect = 4.527e-45
Identity = 103/260 (39.62%), Postives = 136/260 (52.31%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE-------ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILEL 1710
            G FGEVY G+      K     VAVK    N        F+ME  I+    +H N+++ IG       + IVME  + G  L  L+      S  +   L  +    A+GM YL S N IHRDLAARN  V E  VLKI DFG++R+       A    RQI     PI+W A E+L Y  Y+TMSD+WS+GILLWEIFSLG +PY   ++  +  + +  G R   P  C   IY++M + W   A +RPTFT++  EL
Sbjct:  567 GNFGEVYAGRL-----KASGVPVAVKACHENLSQDLKNRFLMEARILKRY-NHPNVVRLIGVCTRRTPVYIVMELVRGGDFLTFLRR---EGSRLSVPQLLNYSEQAAAGMAYLESHNCIHRDLAARNCLVGEASVLKISDFGMSRQQADGVYLATGVMRQI-----PIKWTAPEALHYGTYTTMSDVWSYGILLWEIFSLGSSPYPGWSN-KMACEQVASGYRMPPPAVCPDGIYSLMLRCWEFHAEQRPTFTELHREL 811
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009736.1 (pep scaffold:Pmarinus_7.0:GL479388:5844:12989:-1 gene:ENSPMAG00000008798.1 transcript:ENSPMAT00000009736.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.91 bits (385), Expect = 6.968e-43
Identity = 82/225 (36.44%), Postives = 129/225 (57.33%), Query Frame = 1 
Query: 1066 NFIMEKDIMANLGDHDNIIKYIGF-INLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YY--RQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
             F+ E  +M N   H+N++  +G  + L     +V+ Y K+G L + L+    +P+  +   L  FG+ VA GMEYL+S   +HRDLAARN  + E + +K+ DFGL R+  N  YY  R     K+PI+W+ALESL  ++++T SD+WSFG+LLWE+ + G  PY +V     +   +  G+R  QP +C   ++  M   W   A +RP F +++  L+ + S
Sbjct:    9 QFLREGLLMKNF-QHENVLSLLGICMPLHGTPLVVLPYMKHGDLGHFLRQETHNPTVKD---LIGFGLQVARGMEYLASKKFVHRDLAARNCMLDESYTVKVADFGLARDIYNKEYYSIRNHQRAKLPIKWIALESLQTQRFTTKSDVWSFGVLLWELQTRGAPPYPDVDPFD-MARFLRQGRRLPQPEYCPDELFERMLDCWGPTAGDRPGFPELVRRLELLQS 228
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7])

HSP 1 Score: 157.147 bits (396), Expect = 3.805e-42
Identity = 104/262 (39.69%), Postives = 138/262 (52.67%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNA-PSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGK----VPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSD 1728
            +G FGEV+ G        N  TLVAVK LK  A     FI E  IM  L  H N+I+     +  + I I+ E  ++GSLL+ L+          E  L      +A+GM YL S N IHRDLAARN+ V E  V K+ DFGL R     Y    EGK    VPI+W A E++ + ++S  SD+WSFGILL+E+ + G+ PY E+ ++ +L  L   G R  QP  C    Y+IM + W+    ERPTF  +   L    SD
Sbjct:  197 AGMFGEVWQGLW------NNSTLVAVKTLKPGAMKKEEFIGEAQIMKQL-RHANLIQLYAVCSQEEPIYIITELMRHGSLLDYLRGPLGKQLKAPE--LVDMARQIAAGMAYLESQNYIHRDLAARNILVGEGKVCKVADFGLARIIKVRYEDEYEGKAGAKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELITYGRMPYPEMGNMEVLKQLD-RGYRMPQPDNCPPLFYSIMLECWNKKEEERPTFETLQWRLDYFDSD 448
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 86.2705 bits (212), Expect = 4.936e-18
Identity = 71/208 (34.13%), Postives = 110/208 (52.88%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYT--LVAVK-LLKHNAPSGNFIM-EKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISL 1572
            G +G VY  KA      NK+T  +VA+K ++  N    N IM E  ++ NL +H+NI+KY GFI    ++ I++EY  NGSL  L+     S +  +E     +      G++YL    +IHRD+ A N+ +S    +K+ DFG++    N       G   + W+A E L  +  ST+SDIWS G  + E+ +    PYH +TD ++
Sbjct:   34 GSYGVVY--KAI-----NKHTDQVVAIKEVVYENDEELNDIMAEISLLKNL-NHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISR---SSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVS-TIVNSSALTLAGT--LNWMAPEILGNRGASTLSDIWSLGATVVEMLT-KNPPYHNLTDANI 226
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 82.4185 bits (202), Expect = 9.074e-17
Identity = 55/199 (27.64%), Postives = 105/199 (52.76%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQIN-EGKVPIRWLALESLLYKK-YSTMSDIWSFGILLWEIFSLGQTPY 1548
            +GE   V   +   ++ +N+  L  V+ L+          E   + +L DH NI++Y+GF N  +  ++ +EY   GS+ +L++ +       +E ++      V  G+ YL S  ++HRD+ A N+ + +  + KI DFG++R++ + Y   +   +  + W+A E +  K+ YS   DIWS G ++ E+F+ G+ P+
Sbjct: 1197 TGEMMAVKQVEVPKYSSQNEAILSTVEALRS---------EVSTLKDL-DHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMY----GRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPW 1380
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 74.7146 bits (182), Expect = 6.884e-15
Identity = 60/227 (26.43%), Postives = 106/227 (46.70%), Query Frame = 1 
Query:  958 SGEFGEVYL------GKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVF 1620
            +G FG V+L      G+  +     K  +V +K ++H         ++  M  L +H  +I+  G       I +VM+Y + G L +LL+  Q  P+     +   +  +V   +EYL + N+I+RDL   N+ +     +KI DFG  +E       +        ++A E +  K Y+   D WS G+L++E+ + G TP+++ T +    + I+ GK    P F
Sbjct:   78 TGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTN-------DERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNP----VAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTP---DYIAPEVITTKPYNKSVDWWSLGVLIYEMLA-GYTPFYDTTPMKTY-EKILQGKVVYPPYF 288
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 74.7146 bits (182), Expect = 7.661e-15
Identity = 55/204 (26.96%), Postives = 102/204 (50.00%), Query Frame = 1 
Query:  958 SGEFGEVYL------GKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYH 1551
            +G FG V+L      G+  +     K+T+V +K ++H         ++  M ++  H  II+  G      ++ +VM+Y + G L +LL+  Q  P+     +   +  +V   +EYL S ++I+RDL   N+ + +   +KI DFG  +   +    +     P  ++A E +  K Y+   D WSFG+L++E+ + G TP++
Sbjct:   96 TGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTN-------DERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPN----PVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTL--CGTP-DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLA-GYTPFY 284
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473])

HSP 1 Score: 74.7146 bits (182), Expect = 1.638e-14
Identity = 56/215 (26.05%), Postives = 97/215 (45.12%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTL------------VAVKLLK-HNAPSGNFIMEKDIMANLGDHDNIIKYI-GFINLPDKIAIVMEYAKNGSLLNLLKAFQLS-----PSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPY 1548
            G  G VYL K      +N                VA+K ++    P    IM + ++ N    +NI+ ++  +I   +++ ++MEY + G L ++L A   S      S  NE  +     +   G+++L +  +IHRD+ + N+ ++   ++KI DFG   E      +         W+A E +  K Y    D+WS GI+L E+   G+ PY
Sbjct:  369 GASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIE-GEPPY 582
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Nematostella
Match: EDO49315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA0])

HSP 1 Score: 184.111 bits (466), Expect = 6.510e-53
Identity = 101/270 (37.41%), Postives = 155/270 (57.41%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSG---NFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQ--------LSPSNTNERI-LCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
             G FG+V   +A   +  +  T VAVK+LK +A      + + E ++M ++G H NII  +G       + +++EYA+ G+L   L+  +        + P+ T   + L  F   +A GMEYL+S   IHRDLAARN+ V++  +LKI DFGL R+  N  YYR+  +G++P++W+A E+L  + Y+T SD+WSFGI++WEI + G TPY  V  I  L  L+  G R  +PV C   +Y IM+  W+     RPTFT ++    D+ +
Sbjct:   67 EGAFGKVMRAEAFGLHGNSACTTVAVKMLKEDATEQELFDLVSEMEVMKSIGKHINIINLLGTCTQHGPLFVLVEYARWGNLRQFLRDRRPVKDYDDVMEPAETLTLLNLMTFCYQIAKGMEYLASRKCIHRDLAARNILVADDNILKIADFGLARDVHNVDYYRKTTDGRLPVKWMAFEALFDRVYTTQSDVWSFGIVVWEIITFGGTPYPGVP-IEKLCMLLNTGYRMERPVNCSKELYEIMRNCWNENPEARPTFTSLVQAFDDLVA 335
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Nematostella
Match: EDO40994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5K8])

HSP 1 Score: 185.652 bits (470), Expect = 1.019e-52
Identity = 113/301 (37.54%), Postives = 170/301 (56.48%), Query Frame = 1 
Query:  826 PKYGKALGVDSQNYSFPTDLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            P  G+ + +D  NY+ P + +     N +K++    LKL K++G GEFG+VY  K T          VA+K LK  + S   G+F+ E  +M    D  N+I   G ++    + IV E+  NGSL N LK      S  +   L      +ASGM+YLS MN +HRDLAARN+ V+E  V K+ DFGL+RE  +   + + GK+P+RW A E++ Y+K+ST SD+WS+GILLWE FS  + PY + ++  ++ D +  G R   P+ C   I+ IM + W    ++RP+F  I+ +L  +
Sbjct:   26 PTCGQRVYIDPSNYNDPEEALR----NFAKELDKRWLKLEKVIGGGEFGDVY--KGTLKRPGENTIPVAIKTLKQGSTSKNRGDFLSEASVMGQFCD-PNVIFLEGVVSKTHPLMIVTEFMSNGSLDNFLKKMD---SKLSLIQLMGMARGIASGMKYLSEMNFVHRDLAARNILVTETLVCKVADFGLSRELEDSAYETSGGKIPVRWTAPEAIKYRKFSTSSDVWSYGILLWETFSFAERPYWDWSNFEVM-DRVETGYRLPPPMSCPKVIHQIMLECWDADRTKRPSFALIVKQLDSL 315
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Nematostella
Match: EDO49191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA4])

HSP 1 Score: 189.889 bits (481), Expect = 1.358e-52
Identity = 103/267 (38.58%), Postives = 152/267 (56.93%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTN-------ERI----LCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILEL 1710
             G FG V    A    +      VAVK+LK +A      + + E ++M  +G H NII  IG       + +V+EYA  G+L   L+A +  P   N       E++    L  F   VA GMEYL S   IHRDLAARNV VS+  V+KI DFGL R+    +YYR+  +G++P++W+ALE+L  + Y+  SD+W++GIL+WEI + G +PY  +  +  L +L+  G R  QPV C+  +Y +M + WH   ++RPTF +I+ E+
Sbjct:  331 EGAFGRVVKADAIGLPNMPYRCNVAVKMLKEDATEHELADLVSEMEVMKTIGQHVNIINLIGACTQKGPLFVVVEYASQGNLRQFLRARRPIPEYANPLTEPPREKLKLVDLVSFSYQVARGMEYLESKKCIHRDLAARNVLVSDNHVIKIADFGLARDIHDIDYYRKTTDGRLPVKWMALEALFDRVYTAQSDVWAYGILMWEIVTFGGSPYPGIP-LWKLFELLKEGYRMEQPVNCQDDVYALMLRCWHENPNQRPTFAEIVKEM 596
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Nematostella
Match: EDO37886 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEI8])

HSP 1 Score: 179.489 bits (454), Expect = 1.105e-51
Identity = 105/277 (37.91%), Postives = 157/277 (56.68%), Query Frame = 1 
Query:  958 SGEFGEVYLGKAT-----SFNDK-NKYTLVAVKLLKHNAPSGNF---IMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA----FQLSPSNTNERILCQFGI--------DVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            SG FG+V   +A      S  DK ++ T VAVK+LK NA   ++     E  IM +LG+H NII  +G     + + +++EYAK+G+LL  L+     ++ +   T      +F +         +A GM++L+S   IHRDLAARNV V E + LKIGDFGL R+    + Y +   G +P++W+A E+L  ++YS+ +D+W+FG++LWEI +LG +PY  V  +  L D I  GKR  QP  C   IY IM   W      RPTF +++  ++ I
Sbjct:   23 SGAFGQVIKAEAIGILSLSARDKTSEATTVAVKMLKENASESDYKDLASELKIMIHLGEHKNIINLLGACTRGENLMLILEYAKHGNLLQFLRTRRDIYEPTWKKTTFNPKTEFTLADQVVDAYQIAQGMDFLASKKCIHRDLAARNVLVDEGYALKIGDFGLARDIYKTDLYVKKGAGLLPVKWMAPEALFDREYSSKTDVWAFGVVLWEILTLGGSPYPGVP-LEQLLDYINEGKRMAQPRDCPPEIYAIMCDCWSLEQDRRPTFAELVRRIERI 298
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Nematostella
Match: EDO33736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRD7])

HSP 1 Score: 180.259 bits (456), Expect = 6.228e-51
Identity = 113/299 (37.79%), Postives = 161/299 (53.85%), Query Frame = 1 
Query:  850 VDSQNYSFPTDLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGN---FIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYR------QINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            +D  NY  P     ++  +++K++    LKL  I+G GEF +VY G  T  N+      VAVK+LK  +   N   F +E  IM    DH N+I   G I     + I+ E+ +NGSL N LK+   +        L   G  VA+GM YLS MN IHRDLAARN+ VS+    K+ DFGL+RE  +         Q   GK+P+RW A E++ Y+K+S+ SD+WS+GILLWEI S G+ PY    +  ++ D +  G R   P+ C   I+N+M   W    + RP F DI+    ++
Sbjct:    3 IDPSNYGDPM----EALMSVAKEINKDDLKLEIIIGGGEFADVYRGVLT--NEDKTQEKVAVKILKPGSSHKNREDFCVEASIMGQF-DHPNVIALKGVITRTRPMMIITEFLENGSLDNFLKS---NDGRLTTLQLVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSRELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVM-DRVEGGYRLPAPMKCPKVIHNLMLDCWDKEKTSRPKFADIVRRFDEV 290
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Medaka
Match: fgfr1 (fibroblast growth factor receptor 1 [Source:NCBI gene;Acc:100125448])

HSP 1 Score: 190.274 bits (482), Expect = 3.546e-51
Identity = 133/420 (31.67%), Postives = 208/420 (49.52%), Query Frame = 1 
Query:  562 TVTMFDNSPI-EYKISNATINDSGIYYCQALY--DYQYSKMINLKFQQCSNKSDGYLQFNTLIVGLMIGLFLPL------------FALVLFCIKKRVGSKITPKYGKALGVDSQNYSFPTDL---ITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAF------------QLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILEL 1710
            TVT +D + + +Y  ++ T  + GIY C   +      +  + +K +  S KSD    FN+ +    +   +PL             + V+     R+ S  +P      GV    Y  P D    + +    L K +             G FG+V +G+    + +  N+ T VAVK+LK +A      + I E ++M  +G H NII  +G       + +++EYA  G+L   L+A             Q+S    + + L      VA GMEYL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S+RPTF  ++ +L
Sbjct:  368 TVTKYDPAAVTQYPPTSHTYLEVGIY-CAGFFFIAVMVAIAVIIKIRSTSKKSD----FNSQLAVHKLAKSIPLRRQVSVDSSSSNHSGVMLVRPSRLSSSASPMLS---GV--SEYELPQDPRWEVPRDKLVLGKPLG-----------EGCFGQVMMGEVLGLDKEKPNRVTNVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPDQVSVETMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDL 765
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Medaka
Match: ENSORLT00000000391.2 (fibroblast growth factor receptor 1-A [Source:NCBI gene;Acc:101155126])

HSP 1 Score: 184.111 bits (466), Expect = 1.865e-49
Identity = 108/291 (37.11%), Postives = 155/291 (53.26%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKN--KYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAF------------QLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI--------YSDCSCNLVRY 1752
            G FG+V L +A   +     + T VAVK+LK +A      + I E ++M  +G H NII  +G       + +V+EYA  G+L   L+A             Q        R L      VA GM YL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S RPTF  ++ +L           Y D S  L++Y
Sbjct:  399 GCFGQVVLAEAVGLDRSKPARLTKVAVKMLKADASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQEGPLYVVVEYASKGNLREYLRARRPVGGEYWSGARQPLLGGVEIRELVSAAYQVARGMSYLASKKCIHRDLAARNVLVTEDDVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMEKPSACTQELYLMMRDCWHAVPSRRPTFQQLVEDLDRTLSLMSNQEYLDLSVPLIQY 688
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Medaka
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:100049424])

HSP 1 Score: 182.956 bits (463), Expect = 3.372e-49
Identity = 99/275 (36.00%), Postives = 154/275 (56.00%), Query Frame = 1 
Query:  958 SGEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKA------------FQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
             G FG+V + +A   + +  NK   VA K+LK +A      + + E ++M  +G H NII  +G       + +++E+A  G+L   L+A             ++       + L      VA GMEYL+S   IHRDLAARNV V++  V+KI DFGL R+  N  YY++   G++P++W+A E+L  + Y+  SD+WS+G+LLWEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y IM++ WH + S+RPTF  ++ +L  I S
Sbjct:  357 EGCFGQVVMAEAIGIDKEKPNKPLTVAAKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEFASKGNLREYLRARRPPGMDYSFDTCKIPDEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDLDRILS 630
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Medaka
Match: ENSORLT00000040527.1 (fibroblast growth factor receptor 1-A [Source:NCBI gene;Acc:101155126])

HSP 1 Score: 182.956 bits (463), Expect = 6.087e-49
Identity = 104/274 (37.96%), Postives = 149/274 (54.38%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKN--KYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAF------------QLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTRE--ACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V L +A   +     + T VAVK+LK +A      + I E ++M  +G H NII  +G       + +V+EYA  G+L   L+A             Q        R L      VA GM YL+S   IHRDLAARNV V+E  V+KI DFGL R+    +YY++   G++P++W+A E+L  + Y+  SD+WSFG+LLWEIF+LG +PY  V  +  L  L+  G R  +P  C   +Y +M+  WH + S RPTF  ++ +L    S
Sbjct:  399 GCFGQVVLAEAVGLDRSKPARLTKVAVKMLKADASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQEGPLYVVVEYASKGNLREYLRARRPVGGEYWSGARQPLLGGVEIRELVSAAYQVARGMSYLASKKCIHRDLAARNVLVTEDDVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMEKPSACTQELYLMMRDCWHAVPSRRPTFQQLVEDLDRTLS 671
[Close]
BLAST of Fibroblast growth factor receptor vs. Ensembl Medaka
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:100049424])

HSP 1 Score: 183.341 bits (464), Expect = 7.921e-49
Identity = 100/274 (36.50%), Postives = 157/274 (57.30%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDK--NKYTLVAVKLLKHNAPS---GNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSN--------TNERI----LCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACN--YYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYS 1725
            G FG+V + +A   + +  NK   VA K+LK +A      + + E ++M  +G H NII  +G       + +++E+A  G+L   L+A +    +         +E++    L      VA GMEYL+S   IHRDLAARNV V++  V+KI DFGL R+  N  YY++   G++P++W+A E+L  + Y+  SD+WS+G+LLWEIF+LG +PY  +  +  L  L+  G R  +P  C   +Y IM++ WH + S+RPTF  ++ +L  I S
Sbjct:  489 GCFGQVVMAEAIGIDKEKPNKPLTVAAKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEFASKGNLREYLRARRPPGMDYSFDTCKIPDEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDLDRILS 761
[Close]
BLAST of Fibroblast growth factor receptor vs. Planmine SMEST
Match: SMESG000022068.1 (SMESG000022068.1)

HSP 1 Score: 837.025 bits (2161), Expect = 0.000e+0
Identity = 418/419 (99.76%), Postives = 418/419 (99.76%), Query Frame = 1 
Query:  499 MRRNNQFIGRKMKKFIRCKNKTVTMFDNSPIEYKISNATINDSGIYYCQALYDYQYSKMINLKFQQCSNKSDGYLQFNTLIVGLMIGLFLPLFALVLFCIKKRVGSKITPKYGKALGVDSQNYSFPTDLITQSTFNLSKQMXXXXXXXXXXXXSGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSDCSCNLVRYE 1755
            MRRNNQFIGRKMKKFIRCKNKTVTMFDNSPIEYKISNATINDSGIYYCQALYDYQYSKMINL FQQCSNKSDGYLQFNTLIVGLMIGLFLPLFALVLFCIKKRVGSKITPKYGKALGVDSQNYSFPTDLITQSTFNLSKQMKLGTLKLIKILGSGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSDCSCNLVRYE
Sbjct:    1 MRRNNQFIGRKMKKFIRCKNKTVTMFDNSPIEYKISNATINDSGIYYCQALYDYQYSKMINLTFQQCSNKSDGYLQFNTLIVGLMIGLFLPLFALVLFCIKKRVGSKITPKYGKALGVDSQNYSFPTDLITQSTFNLSKQMKLGTLKLIKILGSGEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDIYSDCSCNLVRYE 419
[Close]
BLAST of Fibroblast growth factor receptor vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 196.823 bits (499), Expect = 1.163e-53
Identity = 101/263 (38.40%), Postives = 155/263 (58.94%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGN---FIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPS-------NTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG VY G       K  +T VAVK+++ +    N   F+ E +IM ++G H N+I+ +G       + +++E A  G+L + +++     S       N    IL  +   +A+GM YL+S +++HRDL+ARN+ V E + +KI DFGLTR    YYR+  +G +P++W+A E+LL KKY+T SD+WS+GILLWEIF+LG  PY  +    ++ D+I  G +N QP      IY++MQ  W+     RP F +I+  L+DI
Sbjct:  552 GAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENLTASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVV-DVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETLQDI 813
[Close]
BLAST of Fibroblast growth factor receptor vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 196.823 bits (499), Expect = 1.232e-53
Identity = 101/263 (38.40%), Postives = 155/263 (58.94%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGN---FIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPS-------NTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG VY G       K  +T VAVK+++ +    N   F+ E +IM ++G H N+I+ +G       + +++E A  G+L + +++     S       N    IL  +   +A+GM YL+S +++HRDL+ARN+ V E + +KI DFGLTR    YYR+  +G +P++W+A E+LL KKY+T SD+WS+GILLWEIF+LG  PY  +    ++ D+I  G +N QP      IY++MQ  W+     RP F +I+  L+DI
Sbjct:  531 GAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENLTASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVV-DVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETLQDI 792
[Close]
BLAST of Fibroblast growth factor receptor vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 196.823 bits (499), Expect = 1.369e-53
Identity = 101/263 (38.40%), Postives = 155/263 (58.94%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGN---FIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPS-------NTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG VY G       K  +T VAVK+++ +    N   F+ E +IM ++G H N+I+ +G       + +++E A  G+L + +++     S       N    IL  +   +A+GM YL+S +++HRDL+ARN+ V E + +KI DFGLTR    YYR+  +G +P++W+A E+LL KKY+T SD+WS+GILLWEIF+LG  PY  +    ++ D+I  G +N QP      IY++MQ  W+     RP F +I+  L+DI
Sbjct:  548 GAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENLTASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVV-DVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETLQDI 809
[Close]
BLAST of Fibroblast growth factor receptor vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 196.438 bits (498), Expect = 1.565e-53
Identity = 101/263 (38.40%), Postives = 155/263 (58.94%), Query Frame = 1 
Query:  961 GEFGEVYLGKATSFNDKNKYTLVAVKLLKHNAPSGN---FIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNLLKAFQLSPS-------NTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEFWVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSFGILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQKTWHTIASERPTFTDIILELKDI 1719
            G FG VY G       K  +T VAVK+++ +    N   F+ E +IM ++G H N+I+ +G       + +++E A  G+L + +++     S       N    IL  +   +A+GM YL+S +++HRDL+ARN+ V E + +KI DFGLTR    YYR+  +G +P++W+A E+LL KKY+T SD+WS+GILLWEIF+LG  PY  +    ++ D+I  G +N QP      IY++MQ  W+     RP F +I+  L+DI
Sbjct:  548 GAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENLTASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVV-DVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETLQDI 809
The following BLAST results are available for this feature:
BLAST of Fibroblast growth factor receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FGFR13.449e-5139.42fibroblast growth factor receptor 1 [Source:HGNC S... [more]
FGFR14.032e-5139.42fibroblast growth factor receptor 1 [Source:HGNC S... [more]
FGFR14.662e-5139.42fibroblast growth factor receptor 1 [Source:HGNC S... [more]
FGFR17.354e-5139.42fibroblast growth factor receptor 1 [Source:HGNC S... [more]
FGFR18.356e-5139.42fibroblast growth factor receptor 1 [Source:HGNC S... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egl-157.627e-4637.37Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-157.627e-4637.37Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-157.627e-4637.37Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-157.627e-4637.37Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-157.646e-4637.37Myoblast growth factor receptor egl-15 [Source:Un... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
btl3.112e-5134.17gene:FBgn0285896 transcript:FBtr0100676[more]
btl3.112e-5134.17gene:FBgn0285896 transcript:FBtr0075778[more]
Csk1.270e-4940.16gene:FBgn0262081 transcript:FBtr0300549[more]
Csk1.270e-4940.16gene:FBgn0262081 transcript:FBtr0300547[more]
Csk1.270e-4940.16gene:FBgn0262081 transcript:FBtr0300548[more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr31.468e-5136.46fibroblast growth factor receptor 3 [Source:NCBI g... [more]
fgfr1b2.263e-5038.29fibroblast growth factor receptor 1b [Source:ZFIN;... [more]
fgfr1b3.716e-5037.96fibroblast growth factor receptor 1b [Source:ZFIN;... [more]
fgfr1a5.726e-5037.41fibroblast growth factor receptor 1a [Source:NCBI ... [more]
fgfr1a5.726e-5037.41fibroblast growth factor receptor 1a [Source:NCBI ... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tirap1.546e-5138.32toll-interleukin 1 receptor (TIR) domain containin... [more]
tirap1.918e-5138.32toll-interleukin 1 receptor (TIR) domain containin... [more]
tirap1.936e-5138.32toll-interleukin 1 receptor (TIR) domain containin... [more]
c1orf846.817e-5128.52chromosome 1 open reading frame 84 [Source:Xenbase... [more]
tirap7.054e-5138.32toll-interleukin 1 receptor (TIR) domain containin... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fgfr12.636e-5139.42fibroblast growth factor receptor 1 [Source:MGI Sy... [more]
Fgfr12.636e-5139.42fibroblast growth factor receptor 1 [Source:MGI Sy... [more]
Fgfr12.768e-5139.42fibroblast growth factor receptor 1 [Source:MGI Sy... [more]
Fgfr16.348e-5139.42fibroblast growth factor receptor 1 [Source:MGI Sy... [more]
Fgfr16.692e-5139.42fibroblast growth factor receptor 1 [Source:MGI Sy... [more]
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BLAST of Fibroblast growth factor receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8MY86|FGFR1_DUGJA1.101e-5238.40Fibroblast growth factor receptor 1 OS=Dugesia jap... [more]
sp|Q09147|FGFR2_DROME3.119e-5034.17Fibroblast growth factor receptor homolog 2 OS=Dro... [more]
sp|P11362|FGFR1_HUMAN4.152e-5039.42Fibroblast growth factor receptor 1 OS=Homo sapien... [more]
sp|P16092|FGFR1_MOUSE4.441e-5039.42Fibroblast growth factor receptor 1 OS=Mus musculu... [more]
sp|Q91285|FGFR1_PLEWA7.863e-5038.04Fibroblast growth factor receptor 1 OS=Pleurodeles... [more]
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BLAST of Fibroblast growth factor receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
B0XJJ28.766e-5633.01Testis-specific serine/threonine-protein kinase 6 ... [more]
R7TUN22.083e-5533.41Protein kinase domain-containing protein OS=Capite... [more]
A0A2P2ICI73.742e-5540.77Fibroblast growth factor receptor 2-like (Fragment... [more]
A0A1J1J5256.056e-5436.72Fibroblast growth factor receptor OS=Clunio marinu... [more]
A0A1J1J6U36.673e-5436.72Fibroblast growth factor receptor OS=Clunio marinu... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr1a5.240e-5139.03fibroblast growth factor receptor 1a [Source:NCBI ... [more]
fgfr21.144e-4937.59fibroblast growth factor receptor 2 [Source:NCBI g... [more]
fgfr31.859e-4930.11fibroblast growth factor receptor 3 [Source:NCBI g... [more]
fgfr35.845e-4936.59fibroblast growth factor receptor 3 [Source:NCBI g... [more]
met1.359e-4840.47MET proto-oncogene, receptor tyrosine kinase [Sour... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr24.464e-5235.96fibroblast growth factor receptor 2 [Source:NCBI g... [more]
NTRK24.496e-4933.46neurotrophic receptor tyrosine kinase 2 [Source:HG... [more]
fer4.527e-4539.62fer (fps/fes related) tyrosine kinase [Source:ZFIN... [more]
ENSPMAT00000009736.16.968e-4336.44pep scaffold:Pmarinus_7.0:GL479388:5844:12989:-1 g... [more]
frk3.805e-4239.69fyn-related Src family tyrosine kinase [Source:ZFI... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
CDC154.936e-1834.13Protein kinase of the Mitotic Exit Network; locali... [more]
BCK19.074e-1727.64MAPKKK acting in the protein kinase C signaling pa... [more]
TPK26.884e-1526.43cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK37.661e-1526.96cAMP-dependent protein kinase catalytic subunit; p... [more]
SKM11.638e-1426.05Member of the PAK family of serine/threonine prote... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO493156.510e-5337.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO409941.019e-5237.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO491911.358e-5238.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO378861.105e-5137.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO337366.228e-5137.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Fibroblast growth factor receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr13.546e-5131.67fibroblast growth factor receptor 1 [Source:NCBI g... [more]
ENSORLT00000000391.21.865e-4937.11fibroblast growth factor receptor 1-A [Source:NCBI... [more]
fgfr33.372e-4936.00fibroblast growth factor receptor 3 [Source:NCBI g... [more]
ENSORLT00000040527.16.087e-4937.96fibroblast growth factor receptor 1-A [Source:NCBI... [more]
fgfr37.921e-4936.50fibroblast growth factor receptor 3 [Source:NCBI g... [more]
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BLAST of Fibroblast growth factor receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000022068.10.000e+099.76SMESG000022068.1[more]
SMESG000054557.11.163e-5338.40SMESG000054557.1[more]
SMESG000054557.11.232e-5338.40SMESG000054557.1[more]
SMESG000054557.11.369e-5338.40SMESG000054557.1[more]
SMESG000054557.11.565e-5338.40SMESG000054557.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30030751 ID=SMED30030751|Name=Fibroblast growth factor receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1847bp
ATCAACTAATTTTTCGTTTATATTCGGAAATAATCACAATTATGAATTTG
GATTTATTAATGATAAAGTAGAACTTTTTGTGATAGATAAAGATGGGCCA
TTTGAAATGTCATGTTCTTATTATACCAATAGTGCTAAAGATTATAAAGT
GAAATGGCTGAAATCATTAGAGGAAATTTCGGAAGATCTATTATTTCTAA
TTATGTTGAACAAGTAAATTGTACTGATGGATTAGTTAATTCTTCAGTAC
TTTGTTTCAACCACATCCTTTCATTTAAACATGTCTGTCCAACAGATCTG
GGTATTTATCAATGCATGATAGTTCATGATTATATTGATAGTAGTGACAT
TTCCAACATGAACGTGATTACTAAACAAGTTGTATATAAACCAATTAAAA
TAGAAATTATTTTTAATCATTTGGACAAGCCATGTTTGAATTCTAATATC
CGCTTACGATGCAATGTAACACCAAGAGCTTTTGATGTTCAATTATTTAT
GCGCCGGAATAACCAATTTATTGGAAGAAAGATGAAAAAGTTTATAAGAT
GCAAAAATAAAACTGTTACCATGTTTGACAATAGCCCTATTGAATATAAG
ATCAGTAATGCCACAATCAATGATTCCGGGATATACTATTGCCAAGCATT
GTACGATTACCAGTATTCCAAAATGATCAATCTCAAATTTCAGCAGTGTT
CTAATAAATCTGATGGATATTTACAATTTAATACATTAATTGTCGGTTTA
ATGATTGGCTTATTCTTGCCTTTGTTTGCTTTGGTACTATTTTGCATAAA
AAAGAGAGTGGGTTCCAAAATAACACCTAAATACGGAAAAGCTTTGGGTG
TTGATTCTCAGAATTATAGTTTTCCCACAGATCTTATTACGCAATCTACA
TTTAATCTCTCTAAACAAATGAAACTGGGTACATTGAAGCTAATTAAAAT
TCTTGGTTCGGGCGAGTTCGGTGAAGTTTATCTCGGTAAAGCCACGAGTT
TTAATGATAAAAACAAATATACATTGGTTGCTGTTAAGTTATTAAAACAT
AACGCACCAAGCGGGAATTTTATAATGGAAAAAGATATTATGGCTAATTT
GGGTGACCATGATAACATTATCAAATACATTGGTTTCATTAATTTACCAG
ATAAAATTGCAATTGTTATGGAATATGCTAAAAATGGCAGTTTGTTAAAT
TTACTAAAAGCATTTCAGCTTTCACCTTCTAACACAAATGAACGTATATT
ATGCCAATTTGGTATCGATGTGGCCTCTGGAATGGAATATTTATCTTCAA
TGAATTTGATTCACAGGGATCTGGCTGCGAGAAATGTTTTTGTTTCTGAA
TTTTGGGTTTTGAAAATTGGAGATTTTGGATTAACAAGAGAAGCTTGCAA
TTATTATCGTCAAATTAACGAAGGTAAAGTCCCTATTCGCTGGCTTGCTT
TAGAATCTTTGCTTTACAAAAAATATTCAACAATGAGTGATATATGGTCA
TTTGGTATTTTACTCTGGGAAATATTTTCTCTTGGACAAACACCTTATCA
TGAAGTAACAGACATAAGTTTATTAACTGATCTTATTGTACATGGGAAAA
GAAACCTTCAGCCAGTATTTTGTAGATTGGCAATATACAATATCATGCAA
AAAACTTGGCATACTATAGCATCAGAAAGGCCTACATTTACTGATATTAT
TTTGGAACTGAAAGATATATATTCCGATTGTTCTTGTAATCTAGTCCGCT
ACGAGTGATATTTTAAACGATAATAACTTTTCAGTCTTTTTTAAATGCAT
TTTATAATTTTTGTATTTTTTAAAATAAATTTGGTTTTAATAAAAAA
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protein sequence of SMED30030751-orf-1

>SMED30030751-orf-1 ID=SMED30030751-orf-1|Name=SMED30030751-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=535bp
MAEIIRGNFGRSIISNYVEQVNCTDGLVNSSVLCFNHILSFKHVCPTDLG
IYQCMIVHDYIDSSDISNMNVITKQVVYKPIKIEIIFNHLDKPCLNSNIR
LRCNVTPRAFDVQLFMRRNNQFIGRKMKKFIRCKNKTVTMFDNSPIEYKI
SNATINDSGIYYCQALYDYQYSKMINLKFQQCSNKSDGYLQFNTLIVGLM
IGLFLPLFALVLFCIKKRVGSKITPKYGKALGVDSQNYSFPTDLITQSTF
NLSKQMKLGTLKLIKILGSGEFGEVYLGKATSFNDKNKYTLVAVKLLKHN
APSGNFIMEKDIMANLGDHDNIIKYIGFINLPDKIAIVMEYAKNGSLLNL
LKAFQLSPSNTNERILCQFGIDVASGMEYLSSMNLIHRDLAARNVFVSEF
WVLKIGDFGLTREACNYYRQINEGKVPIRWLALESLLYKKYSTMSDIWSF
GILLWEIFSLGQTPYHEVTDISLLTDLIVHGKRNLQPVFCRLAIYNIMQK
TWHTIASERPTFTDIILELKDIYSDCSCNLVRYE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005007fibroblast growth factor-activated receptor activity
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
GO:0005515protein binding
GO:0000166nucleotide binding
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0008284positive regulation of cell proliferation
GO:0008543fibroblast growth factor receptor signaling pathway
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0018108peptidyl-tyrosine phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR036179Ig-like_dom_sf
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR013783Ig-like_fold
IPR017441Protein_kinase_ATP_BS
IPR008266Tyr_kinase_AS
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom_sf
IPR007110Ig-like_dom
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 372..382
score: 49.42
coord: 285..298
score: 44.65
coord: 436..458
score: 36.25
coord: 325..343
score: 63.3
coord: 391..413
score: 59.21
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 207..464
e-value: 9.4E-78
score: 261.1
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 207..465
e-value: 1.0E-100
score: 350.6
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 200..472
e-value: 1.4E-69
score: 236.1
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 304..475
e-value: 4.5E-50
score: 168.3
coord: 6..141
e-value: 0.63
score: 5.7
coord: 63..309
e-value: 7.1E-14
score: 48.5
NoneNo IPR availablePANTHERPTHR24418TYROSINE-PROTEIN KINASEcoord: 110..470
NoneNo IPR availableCDDcd00192PTKccoord: 211..466
e-value: 2.52647E-102
score: 304.847
NoneNo IPR availableTMHMMTMhelixcoord: 135..157
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 41..137
e-value: 1.8E-6
score: 29.6
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 331..343
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 213..241
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 207..470
score: 36.57
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 186..462
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 41..118